| Substance Name | Substance Category | Substance Subcategory | Associated Microbe Count |
|---|---|---|---|
| 5-Fluorouracil | Therapeutic Substance | antineoplastic antimetabolite | 1869 |
| Gemcitabine | Therapeutic Substance | chemotherapy | 1635 |
| Trifluridine | Therapeutic Substance | deglycosylation | 1633 |
| Sorivudine | Therapeutic Substance | antiviral | 1514 |
| Rutin | Therapeutic Substance; Herbal Substance | decrease capillary fragility | 1385 |
| Ginsenoside | Therapeutic substance | reproductive system in animal testicles | 1380 |
| Naringin | Herbal Substance | Anti-oxidant, anti-cancer and blood cholesterol lowering effect | 1325 |
| Isoquercetin(uercitin-3-glucoside) | Therapeutic substance | n.a. | 1324 |
| Anthocyanins | Therapeutic substance | Potential anticancer, anti-oxidant and anti-inflammatory | 1323 |
| Amygdalin | Herbal Substance; Dietary Substance | Herbal Substance | 1322 |
| Rebaudioside A | Therapeutic Substance | compound | 1322 |
| Steviol glycosides | Therapeutic Substance | unknown | 1322 |
| Stevioside | Therapeutic Substance | compound | 1322 |
| Capecitabine | Therapeutic Substance | chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers. | 1046 |
| Poncirin | Therapeutic substance | unknown | 574 |
| Aspirin | Therapeutic substance | pain and fever due to various causes | 467 |
| Ketoprofen | Therapeutic Substance; Herbal Substance | anti-inflammatory | 361 |
| Irinotecan | Therapeutic Substance | antineoplastic enzyme inhibitor | 359 |
| Indomethacin | Therapeutic Substance | NSAID | 357 |
| Diclofenac | Therapeutic Substance | anti-inflammatory | 356 |
| Nitrotoluene | Therapeutic substance | compound | 355 |
| Serotonin dopamine | Therapeutic substance | compound | 355 |
| Tryptophan | Therapeutic Substance; Herbal Substance | amino acid commonly found | 298 |
| Mesalazine | Therapeutic Substance | anti-inflammatory | 164 |
| Choline | Therapeutic Substance; Herbal Substance | compound | 156 |
| Amphetamine | Therapeutic Substance | attention-deficit/hyperactivity disorders (ADHD) | 103 |
| Omeprazole | Therapeutic Substance | Approved Drug | 78 |
| Bisacodyl | Therapeutic Substance | Approved Drug | 77 |
| Melphalan | Therapeutic Substance | Approved Drug | 76 |
| Pantoprazole | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 76 |
| Artemisinin | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 75 |
| Diacetamate | Therapeutic Substance | Approved Drug | 72 |
| Danazol | Therapeutic Substance | Approved Drug | 70 |
| Tenatoprazole | Therapeutic Substance | Approved Drug | 70 |
| Entacapone | Therapeutic Substance | Approved Drug | 69 |
| Sulfasalazine | Therapeutic Substance | Approved Drug | 68 |
| Bromocriptine mesylate | Therapeutic Substance | Approved Drug | 67 |
| Mycophenolate mofetil | Therapeutic Substance | Approved Drug | 67 |
| Naringin | Therapeutic Substance | Anti-oxidant, anti-cancer and blood cholesterol lowering effect | 66 |
| Tinidazole | Therapeutic Substance | Approved Drug | 66 |
| Acetaminophen | Therapeutic Substance; Herbal Substance | analgesics | 60 |
| Nitrendipine | Therapeutic Substance | Approved Drug | 60 |
| Phenazopyridine | Therapeutic Substance | Approved Drug | 59 |
| Genistin | Therapeutic substance | Anti-cancer, estrogenic and antiatherosclerotic | 58 |
| Fluoxetine | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 55 |
| Olmesartan medoxomil | Therapeutic Substance | Approved Drug | 49 |
| Racecadotril | Therapeutic Substance | Approved Drug | 40 |
| Levodopa | Therapeutic Substance; Herbal Substance | Parkinson's | 37 |
| Roxatidine acetate | Therapeutic Substance | Approved Drug | 37 |
| Oorethindrone acetate | Therapeutic Substance | Approved Drug | 35 |
| Risperidone | Therapeutic Substance | Approved Drug | 35 |
| Famciclovir | Therapeutic Substance | Approved Drug | 32 |
| Quinapril | Therapeutic Substance | Approved Drug | 32 |
| Riluzole | Therapeutic Substance | Approved Drug | 32 |
| Cetirizine | Therapeutic Substance | Approved Drug | 30 |
| Deflazacort | Therapeutic Substance | Approved Drug | 30 |
| Tolazamide | Therapeutic Substance | Approved Drug | 29 |
| Vilazodone | Therapeutic Substance | Approved Drug | 29 |
| Pranoprofen | Therapeutic Substance | Approved Drug | 28 |
| Lovastatin | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 27 |
| Digoxin | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 26 |
| Levamisole | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 25 |
| Tacrolimus | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 25 |
| Clopidogrel sulfate | Therapeutic Substance | Approved Drug | 24 |
| Digitoxin | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 24 |
| Clemastine fumarate | Therapeutic Substance | Approved Drug | 23 |
| Diflorasone diacetate | Therapeutic Substance | Approved Drug | 23 |
| Levonorgestrel | Therapeutic Substance | Approved Drug | 23 |
| Oxaprozin | Therapeutic Substance | Approved Drug | 23 |
| Trimebutine maleate | Therapeutic Substance | Approved Drug | 23 |
| Benazepril | Therapeutic Substance | Approved Drug | 22 |
| Loperamide | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 22 |
| Megestrol acetate | Therapeutic Substance | Approved Drug | 22 |
| Carisoprodol | Therapeutic Substance | Approved Drug | 21 |
| Famprofazone | Therapeutic Substance | Approved Drug | 21 |
| Idebenone | Therapeutic Substance | Approved Drug | 21 |
| Irinotecan | Therapeutic Substance | Approved Drug | 20 |
| Mebendazole | Therapeutic Substance | Approved Drug | 20 |
| Paliperidone | Therapeutic Substance | Approved Drug | 20 |
| Febuxostat | Therapeutic Substance | Approved Drug | 19 |
| Pidotimod | Therapeutic Substance | Approved Drug | 19 |
| Ramelteon | Therapeutic Substance | Approved Drug | 19 |
| Nateglinide | Therapeutic Substance | Approved Drug | 18 |
| Betamethasone valerate | Therapeutic Substance | Approved Drug | 17 |
| Cyproterone acetate | Therapeutic Substance | Approved Drug | 17 |
| Duloxetine | Therapeutic Substance | Major Depressive Disorder. | 17 |
| Methoxsalen | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 17 |
| Trandolapril | Therapeutic Substance | Approved Drug | 17 |
| Budesonide | Therapeutic Substance | Approved Drug | 16 |
| Carvedilol | Therapeutic Substance | Approved Drug | 16 |
| Fenspiride | Therapeutic Substance | Approved Drug | 16 |
| Indomethacin | Therapeutic Substance | Approved Drug | 16 |
| Irbesartan | Therapeutic Substance | Approved Drug | 16 |
| Procarbazine | Therapeutic Substance | Approved Drug | 16 |
| Ritonavir | Therapeutic Substance | Approved Drug | 16 |
| Valsartan | Therapeutic Substance | Approved Drug | 16 |
| Betamethasone acetate | Therapeutic Substance | Approved Drug | 15 |
| Clonidine | Therapeutic Substance | Approved Drug | 15 |
| Cyclophosphamide | Therapeutic Substance | Approved Drug | 15 |
| diltiazem | Therapeutic Substance | Approved Drug | 15 |
| Fluconazole | Therapeutic Substance | Approved Drug | 15 |
| Linagliptin | Therapeutic Substance | Approved Drug | 15 |
| Mevastatin | Therapeutic Substance | Approved Drug | 15 |
| Nizatidine | Therapeutic Substance | Approved Drug | 15 |
| Ginsenoside Rb1 | Therapeutic Substance; Herbal Substance | Investigational Drug; Medicinal Herbal Compounds | 14 |
| Metformin | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 14 |
| Sulfinpyrazone | Therapeutic Substance | Approved Drug | 14 |
| Voriconazole | Therapeutic Substance | Approved Drug | 14 |
| Colchicine | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 13 |
| Digoxin | Therapeutic Substance; Herbal Substance | cardiac glycoside | 13 |
| Ergonovine maleate | Therapeutic Substance | Approved Drug | 13 |
| Etodolac | Therapeutic Substance | Approved Drug | 13 |
| Finasteride | Therapeutic Substance | Approved Drug | 13 |
| Losartan | Therapeutic Substance | Approved Drug | 13 |
| Mesalazine | Therapeutic Substance | Approved Drug | 13 |
| Metaxalone | Therapeutic Substance | Approved Drug | 13 |
| Telmisartan | Therapeutic Substance | Approved Drug | 13 |
| Ezetimibe | Therapeutic Substance | Approved Drug | 12 |
| Galantamine | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 12 |
| Griseofulvin | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 12 |
| Lovastatin | Therapeutic Substance; Herbal Substance | lower the risk of cardiovascular disease | 12 |
| Naloxone | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 12 |
| Naproxen(+) | Therapeutic Substance | Approved Drug | 12 |
| Neostigmine bromide | Therapeutic Substance | Approved Drug | 12 |
| Rutin | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 12 |
| Sulfasalazine | Therapeutic Substance | anti-inflammatory | 12 |
| Dexamethasone | Therapeutic Substance | Approved Drug | 11 |
| Drospirenone | Therapeutic Substance | Approved Drug | 11 |
| Eszopiclone | Therapeutic Substance | Approved Drug | 11 |
| Fluphenazine | Therapeutic Substance | Approved Drug | 11 |
| Gliclazide | Therapeutic Substance | Approved Drug | 11 |
| Ketorolac tromethamine | Therapeutic Substance | Approved Drug | 11 |
| Oxybutynin chloride | Therapeutic Substance | Approved Drug | 11 |
| Rebamipide | Therapeutic Substance | Approved Drug | 11 |
| Repaglinide | Therapeutic Substance | Approved Drug | 11 |
| Sotalol | Therapeutic Substance | Approved Drug | 11 |
| Zaleplon | Therapeutic Substance | Approved Drug | 11 |
| Zonisamide | Therapeutic Substance | Approved Drug | 11 |
| Dasatinib | Therapeutic Substance | Approved Drug | 10 |
| Ginsenoside Rg3 | Herbal Substance | Medicinal Herbal Compounds | 10 |
| Glipizide | Therapeutic Substance | Approved Drug | 10 |
| Lactulose | Therapeutic Substance | Approved Drug | 10 |
| Lactulose | Therapeutic Substance | laxative | 10 |
| Mifepristone | Therapeutic Substance | Approved Drug | 10 |
| Misoprostol | Therapeutic substance | reduce the risk of NSAID induced gastric ulcers | 10 |
| Montelukast | Therapeutic Substance | Drugs for obstructive airway disease | 10 |
| Paclitaxel | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 10 |
| Praziquantel | Therapeutic substance | Anti-infection | 10 |
| Primaquine phosphate | Therapeutic Substance | Approved Drug | 10 |
| Daidzein | Therapeutic Substance; Herbal Substance | Investigational Drug; Medicinal Herbal Compounds | 9 |
| Duloxetine | Therapeutic Substance | Approved Drug | 9 |
| Mycophenolate mofetil | Therapeutic Substance | inosine monophosphate dehydrogenase inhibitor | 9 |
| Pericyazine | Therapeutic Substance | Approved Drug | 9 |
| Phorbol | Herbal Substance | Medicinal Herbal Compounds | 9 |
| Ranitidine | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 9 |
| Ropinirole | Therapeutic substance | Parkinson's | 9 |
| Sorivudine | Therapeutic Substance | Investigational Drug | 9 |
| Sulindac | Therapeutic Substance | anti-inflammatory | 9 |
| Anagrelide | Therapeutic Substance | Approved Drug | 8 |
| Cimetidine | Therapeutic Substance | Approved Drug | 8 |
| Clofazimine | Therapeutic Substance; Herbal Substance | antimicrobial | 8 |
| Daidzin | Therapeutic Substance; Herbal Substance | Investigational Drug; Medicinal Herbal Compounds | 8 |
| Dicyclomine | Therapeutic Substance | Approved Drug | 8 |
| Dolasetron | Therapeutic substance | antinauseant and antiemetic | 8 |
| Itraconazole | Therapeutic Substance | Approved Drug | 8 |
| Levamisole | Therapeutic Substance; Herbal Substance | Therapeutic Substance; Herbal Substance | 8 |
| Levonorgestrel | Therapeutic Substance | contraception and hormone | 8 |
| Oorgestimate | Therapeutic Substance | Approved Drug | 8 |
| Ramipril | Therapeutic Substance | Approved Drug | 8 |
| Risperidone | Therapeutic Substance | second-generation antipsychotic (SGA) | 8 |
| Spironolactone | Therapeutic substance | diuretic and also antihypertensive effects | 8 |
| Tolcapone | Therapeutic substance | Parkinson's | 8 |
| Bezafibrate | Therapeutic Substance | Approved Drug | 7 |
| Carbetapentane citrate | Therapeutic Substance | Approved Drug | 7 |
| Chlormezanone | Therapeutic Substance | Approved Drug | 7 |
| Fenofibrate | Therapeutic Substance | Approved Drug | 7 |
| Ginsenoside Rb1 | Therapeutic Substance; Herbal Substance | Therapeutic Substance; Herbal Substance | 7 |
| Ginsenoside Rb2 | Herbal Substance | Medicinal Herbal Compounds | 7 |
| Ginsenoside Rc | Herbal Substance | Medicinal Herbal Compounds | 7 |
| Ginsenoside Rg5 | Herbal Substance | Medicinal Herbal Compounds | 7 |
| Hydrocortisone | Therapeutic substance | immune, inflammatory, and neoplastic conditions | 7 |
| Imatinib | Therapeutic Substance | Approved Drug | 7 |
| Nicergoline | Therapeutic Substance | Approved Drug | 7 |
| Olanzapine | Therapeutic Substance | Approved Drug | 7 |
| Ooscapine | Therapeutic Substance | Approved Drug | 7 |
| Secoisolariciresinol | Therapeutic Substance | Investigational Drug | 7 |
| Sulfasalazine | Therapeutic Substance | Approved Drug; Prodrug | 7 |
| Acetaminophen | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 6 |
| Berberine | Herbal Substance | Medicinal Herbal Compounds | 6 |
| Daidzein | Therapeutic Substance; Herbal Substance | a weakly estrogenic compound with potential health | 6 |
| Doxorubicin | Therapeutic Substance | Approved Drug | 6 |
| Ketoconazole | Therapeutic Substance; Herbal Substance | fungal infections | 6 |
| Methamphetamine | Therapeutic Substance | psychostimulant and sympathomimetic | 6 |
| Methotrexate | Therapeutic Substance | Approved Drug | 6 |
| Nafronyl oxalate | Therapeutic Substance | Approved Drug | 6 |
| Naringin | Herbal Substance | Medicinal Herbal Compounds | 6 |
| Nicardipine | Therapeutic substance | effective in the treatment of angina and coronary spasms without showing cardiodepressant effects | 6 |
| Scutellaria baicalensis root | Therapeutic Substance | Investigational Drug | 6 |
| Secoisolariciresinol | Therapeutic Substance | anticancer | 6 |
| Torsemide | Therapeutic substance | loop diuretic | 6 |
| Trihexyphenidyl | Therapeutic Substance | Approved Drug | 6 |
| Amantadine | Therapeutic Substance | Approved Drug | 5 |
| Anti-cytotoxic T-lymphocyte-associated antigen 4(CTLA-4) | Therapeutic substance | negative regulators of T cell proliferation and functions | 5 |
| Balsalazide | Therapeutic Substance | anti-inflammatory | 5 |
| Biperiden | Therapeutic Substance | Approved Drug | 5 |
| CTLA-4 blockade | Therapeutic Substance | Drug Class | 5 |
| Cyclophosphamide | Therapeutic Substance | lymphoma and leukemia | 5 |
| Diosmin | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 5 |
| Doxorubicin | Therapeutic Substance; Herbal Substance | chemotherapeutic | 5 |
| Ergotamine tartrate | Therapeutic Substance | Approved Drug | 5 |
| Ethopropazine | Therapeutic Substance | Approved Drug | 5 |
| Genistein | Therapeutic Substance; Herbal Substance | Investigational Drug; Medicinal Herbal Compounds | 5 |
| Ipilimumab | Therapeutic Substance | a human cytotoxic T-lymphocyte antigen 4 (CTLA-4) blocking antibody used to treat metastatic or unresectable melanoma | 5 |
| Irinotecan | Therapeutic Substance | Approved Drug; Prodrug | 5 |
| Isoaminile | Therapeutic Substance | Approved Drug | 5 |
| Levodopa | Therapeutic Substance | Approved Drug | 5 |
| Mefloquine | Therapeutic Substance | Approved Drug | 5 |
| Metronidazole | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 5 |
| Nitrazepam | Therapeutic Substance | anticonvulsant and hypnotic | 5 |
| Olsalazine | Therapeutic Substance | anti-inflammatory | 5 |
| Phenytoin sodium | Therapeutic Substance | Approved Drug | 5 |
| Pimozide | Therapeutic Substance | Approved Drug | 5 |
| Tadalafil | Therapeutic Substance | Approved Drug | 5 |
| Tretazicar | Therapeutic Substance | Investigational Drug | 5 |
| Acetylsalicylic acid | Therapeutic Substance | Approved Drug | 4 |
| Anti?PD?1 therapy | Therapeutic Substance | Drug Class | 4 |
| Capecitabine | Therapeutic Substance | Approved Drug | 4 |
| Cladribine | Therapeutic Substance; Herbal Substance | chemotherapeutic | 4 |
| Clonazepam | Therapeutic Substance | Central nervous system agents | 4 |
| Daunorubicin | Therapeutic substance | chemotherapeutic | 4 |
| Dipyridamole | Therapeutic Substance | Approved Drug | 4 |
| Doxazosin mesylate | Therapeutic Substance | Approved Drug | 4 |
| Doxorubicin | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 4 |
| Etoposide | Therapeutic Substance | Approved Drug | 4 |
| Fludarabine de phosphate | Therapeutic substance | chemotherapeutic | 4 |
| Fluvoxamine maleate | Therapeutic Substance | Approved Drug | 4 |
| Ginsenoside Re | Herbal Substance | Medicinal Herbal Compounds | 4 |
| Ginsenoside Rf | Herbal Substance | Medicinal Herbal Compounds | 4 |
| Ginsenoside Rg1 | Herbal Substance | Medicinal Herbal Compounds | 4 |
| Metamfetamine | Therapeutic Substance | Approved Drug | 4 |
| Methylphenidate | Therapeutic Substance | Approved Drug | 4 |
| Penbutolol sulfate | Therapeutic Substance | Approved Drug | 4 |
| Rosiglitazone | Therapeutic substance | Anti-diabetics | 4 |
| Sildenafil citrate | Therapeutic Substance | Approved Drug | 4 |
| Sumatriptan succinate | Therapeutic Substance | Approved Drug | 4 |
| Warfarin | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 4 |
| 5-fluorocytosine | Therapeutic Substance | Approved Drug; Prodrug | 3 |
| 5-fluorouracil | Therapeutic Substance | Approved Drug | 3 |
| Acetylsalicylic acid | Therapeutic Substance | Therapeutic Substance | 3 |
| Altretamine | Therapeutic Substance | Approved Drug | 3 |
| Amoxicillin | Therapeutic Substance | Approved Drug | 3 |
| Anastrozole | Therapeutic Substance | Approved Drug | 3 |
| Anti-axis programmed cell death protein 1 (PD-1) and its ligand (PD-L1) | Therapeutic substance | immune checkpoint repressing T cell response | 3 |
| Arsenic | Environmental Substance | Heavy Metals; Toxic Agents | 3 |
| Balsalazide | Therapeutic Substance | Approved Drug | 3 |
| Bicalutamide | Therapeutic Substance | Approved Drug | 3 |
| Brivudine | Therapeutic Substance | Approved Drug | 3 |
| Brivudine | Therapeutic Substance | Therapeutic Substance | 3 |
| Bupropion | Therapeutic Substance | Approved Drug | 3 |
| carboxymethylcellulose | Therapeutic Substance | Approved Drug | 3 |
| Carmustine, Etoposide, Cytarabine and melphalan combination | Therapeutic Substance | Drug Combination | 3 |
| Cephalosporins | Therapeutic Substance | Drug Class | 3 |
| CpG oligodeoxynucleotides | Therapeutic Substance | Drug Class | 3 |
| Cyclobenzaprine | Therapeutic Substance | Approved Drug | 3 |
| Diclofenac | Therapeutic Substance | Approved Drug | 3 |
| Enalapril maleate | Therapeutic Substance | Approved Drug | 3 |
| Gemcitabine | Therapeutic Substance | Approved Drug | 3 |
| Ginsenosides | Therapeutic Substance | Investigational Drug | 3 |
| Glucuronides | Environmental Chemicals | Environmental Substance | 3 |
| Glucuronides | Environmental Substance | Unclassified Environmental Substances | 3 |
| Glycyrrhizin | Herbal Substance | hepatoprotective | 3 |
| Ipsalazide | Therapeutic Substance | unknown | 3 |
| Levodopa | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 3 |
| Lignans | Herbal Substance; Dietary Substance | Medicinal Herbal Compounds; Dietary Compounds | 3 |
| Memantine | Therapeutic Substance | Approved Drug | 3 |
| Methotrexate | Therapeutic Substance | chemotherapeutic | 3 |
| Metoprolol tartrate | Therapeutic Substance | Approved Drug | 3 |
| Metronidazole | Therapeutic Substance; Herbal Substance | antibiotic | 3 |
| Misonidazole | Therapeutic Substance | Tumor Hypoxia | 3 |
| Nabumetone | Therapeutic Substance | Approved Drug | 3 |
| Nevirapine | Therapeutic Substance | Approved Drug | 3 |
| Nitrazepam | Therapeutic Substance | Approved Drug | 3 |
| Olsalazine | Therapeutic Substance | Approved Drug | 3 |
| Oxaliplatin | Therapeutic Substance | chemotherapy agent | 3 |
| Phenoxyethanol | Therapeutic Substance | Approved Drug | 3 |
| PPIs | Therapeutic Substance | Drug Class | 3 |
| Resveratrol | Therapeutic Substance | Approved Drug | 3 |
| Roflumilast | Therapeutic Substance | Drugs for obstructive airway disease | 3 |
| Rosuvastatin | Therapeutic Substance | Approved Drug | 3 |
| Sorivudine | Therapeutic Substance | Approved Drug | 3 |
| Sulindac | Therapeutic Substance | Approved Drug | 3 |
| Sunitinib | Therapeutic Substance | Approved Drug | 3 |
| Tamoxifen | Therapeutic Substance | Approved Drug | 3 |
| Tempol | Therapeutic Substance | Investigational Drug | 3 |
| Thiopurines | Therapeutic Substance | Drug Class | 3 |
| Trans-resveratrol | Therapeutic Substance | Approved Drug | 3 |
| Tretazicar | Therapeutic Substance | Therapeutic Substance | 3 |
| Vorinostat | Therapeutic substance | Anti-cancer | 3 |
| Ziprasidone mesylate | Therapeutic Substance | Approved Drug | 3 |
| 5-fluoro-2'-deoxyuridine | Therapeutic Substance | Approved Drug | 2 |
| 5-fluoro-2'-deoxyuridine | Therapeutic substance | Therapeutic Substance | 2 |
| 5-fluorocytosine | Therapeutic substance | chemotherapeutic | 2 |
| Acarbose | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 2 |
| Acecainide | Therapeutic Substance | Approved Drug | 2 |
| Alfuzosin | Therapeutic Substance | Approved Drug | 2 |
| Altretamine | Therapeutic Substance | Therapeutic Substance | 2 |
| Amiodarone | Therapeutic Substance | anti-arrhythmic | 2 |
| Amiodarone | Therapeutic Substance | Approved Drug | 2 |
| Amlodipine | Therapeutic Substance | Approved Drug | 2 |
| Anti-PD-L1 therapy | Therapeutic Substance | Drug Class | 2 |
| Antibiotic | Therapeutic Substance | Drug Class | 2 |
| Anticancer drugs | Therapeutic Substance | Drug Class | 2 |
| Ara G hydrate | Therapeutic Substance | Approved Drug | 2 |
| Aspartame | Therapeutic Substance; Dietary Substance; Herbal Substance | Dietary Compounds; Artificial Sweetener; Medicinal Herbal Compounds | 2 |
| Baicalin | Herbal Substance | Medicinal Herbal Compounds | 2 |
| Benzthiazide | Therapeutic Substance | Approved Drug | 2 |
| Bromazepam | Therapeutic Substance | Approved Drug | 2 |
| Butyric Acid | Therapeutic Substance | Investigational Drug | 2 |
| Camptothecin | Therapeutic Substance | Approved Drug | 2 |
| Camptothecin | Therapeutic substance | Therapeutic Substance | 2 |
| CB1954 | Therapeutic Substance | Approved Drug | 2 |
| Celecoxib | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 2 |
| Chloramphenicol | Therapeutic Substance; Herbal Substance | bacteriostatic | 2 |
| Choline-containing compounds | Environmental Substance | Unclassified Environmental Substances | 2 |
| Cladribine | Therapeutic Substance | Approved Drug | 2 |
| Clofarabine | Therapeutic Substance | Approved Drug | 2 |
| Clonazepam | Therapeutic Substance | Approved Drug | 2 |
| Cytarabine | Therapeutic Substance | Approved Drug | 2 |
| Daunorubicin | Therapeutic Substance | Approved Drug | 2 |
| Ellagic acid | Therapeutic Substance; Herbal Substance | Investigational Drug; Medicinal Herbal Compounds | 2 |
| Etoposide | Therapeutic Substance; Herbal Substance | Therapeutic Substance | 2 |
| Floxuridine | Therapeutic Substance | Approved Drug | 2 |
| Flucytosine | Therapeutic Substance | Approved Drug | 2 |
| Fludarabine de phosphate | Therapeutic Substance | Approved Drug | 2 |
| Geniposide | Herbal Substance | Medicinal Herbal Compounds | 2 |
| Genistein | Therapeutic Substance; Herbal Substance | antineoplastic and antitumor | 2 |
| Glycyrrhizic acid | Therapeutic Substance | Approved Drug | 2 |
| Hesperidin | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 2 |
| Hydrocortisone acetate | Therapeutic Substance | immune, inflammatory, and neoplastic conditions | 2 |
| Idarubicin | Therapeutic substance | chemotherapeutic | 2 |
| Linoleic acid | Herbal Substance | Medicinal Herbal Compounds | 2 |
| Menadione | Therapeutic substance | chemotherapeutic | 2 |
| Metformin | Therapeutic Substance; Herbal Substance | Cardiac drugs | 2 |
| Methsuximide | Therapeutic Substance | Approved Drug | 2 |
| Methysergide maleate | Therapeutic Substance | Approved Drug | 2 |
| Miglitol | Therapeutic Substance | Approved Drug | 2 |
| Mitoxantrone | Therapeutic substance | chemotherapeutic | 2 |
| Morphine | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 2 |
| Naftopidil | Therapeutic Substance | Approved Drug | 2 |
| Nelarabine | Therapeutic Substance | Approved Drug | 2 |
| Neocarzinostatin | Therapeutic Substance | Approved Drug | 2 |
| Neocarzinostatin | Therapeutic substance | compound | 2 |
| NSAIDs | Therapeutic Substance | compound | 2 |
| NSAIDs | Therapeutic Substance | Drug Class | 2 |
| Omeprazole | Therapeutic Substance | gastric acid-related disorders | 2 |
| Oxcarbazepine | Therapeutic Substance | Approved Drug | 2 |
| Paclitaxel | Therapeutic Substance | Approved Drug | 2 |
| Paclitaxel | Therapeutic Substance; Herbal Substance | chemotherapeutic agent | 2 |
| Paroxetine | Therapeutic Substance | Approved Drug | 2 |
| PD-1 inhibitors | Therapeutic substance | unknown | 2 |
| Pentostatin | Therapeutic Substance | Approved Drug | 2 |
| Phenoxyethanol | Therapeutic Substance | Therapeutic Substance | 2 |
| Picosulfuric acid | Therapeutic Substance | Approved Drug | 2 |
| Picosulfuric acid | Therapeutic Substance | compound | 2 |
| Pioglitazone | Therapeutic Substance | Approved Drug | 2 |
| Puerarin | Therapeutic Substance; Herbal Substance | Investigational Drug; Medicinal Herbal Compounds | 2 |
| Quercetin-3-glucoside | Herbal Substance; Dietary Substance | compound | 2 |
| Quercetin-3-glucoside | Herbal Substance; Dietary Substance | Medicinal Herbal Compounds; Dietary Compounds | 2 |
| Ranitidine | Therapeutic Substance; Herbal Substance | Drugs for acid related disorders | 2 |
| Rifaximin | Therapeutic Substance | Approved Drug | 2 |
| Saccharin | Therapeutic Substance; Dietary Substance; Herbal Substance | Investigational Drug; Dietary Compounds; Artificial Sweetener; Medicinal Herbal Compounds | 2 |
| Secoisolariciresinol diglucoside | Herbal Substance | Medicinal Herbal Compounds | 2 |
| Sennoside A | Herbal Substance | Medicinal Herbal Compounds | 2 |
| Simvastatin | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 2 |
| Simvastatin | Therapeutic Substance; Herbal Substance | Cardiac drugs | 2 |
| Sulfadiazine | Therapeutic Substance | Approved Drug | 2 |
| Sulfanilamide | Therapeutic Substance; Herbal Substance | anti-infective | 2 |
| Sulfanilamide | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 2 |
| Sulphinpyrazone | Therapeutic Substance | anti-inflammatory | 2 |
| Sunitinib | Therapeutic substance | multi-targeted receptor tyrosine kinase (RTK) inhibitor | 2 |
| Tamoxifen | Therapeutic substance | Therapeutic Substance | 2 |
| Tegafur | Therapeutic Substance | Approved Drug | 2 |
| Tegafur | Therapeutic substance | chemotherapeutic | 2 |
| Temozolomide | Therapeutic Substance | antitumor | 2 |
| Temozolomide | Therapeutic Substance | Approved Drug | 2 |
| Thiopurines | Therapeutic substance | compound | 2 |
| Thiothixene | Therapeutic Substance | Approved Drug | 2 |
| Tranilast | Therapeutic Substance | Approved Drug | 2 |
| Tretazicar(CB1954) | Therapeutic substance | chemotherapeutic | 2 |
| Trifluridine | Therapeutic Substance | Approved Drug | 2 |
| Unspecified antibiotic | Therapeutic Substance | Drug Class | 2 |
| Vancomycin | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 2 |
| Vidarabine | Therapeutic substance | antiviral | 2 |
| Vidarabine | Therapeutic Substance | Approved Drug | 2 |
| Vinpocetine | Therapeutic Substance | Approved Drug | 2 |
| Xylitol | Therapeutic Substance; Herbal Substance; Dietary Substance | Approved Drug; Medicinal Herbal Compounds; Dietary Compounds | 2 |
| Zidovudine | Therapeutic Substance | Approved Drug | 2 |
| Zonisamide | Therapeutic Substance | anticonvulsant | 2 |
| 1-b-D-arabinofuranosyl-5-(E)-(2-bromovinyl)uracil | Environmental Substance | Unclassified Environmental Substances | 1 |
| 2,8-DHQ (including 2,4-DHQ) | Environmental Chemicals | Environmental Substance | 1 |
| 2,8-DHQ (including 2,4-DHQ) | Environmental Substance | Human Metabolite | 1 |
| 2-amino-3,6-dihydro-3H-imidazo[4,5-f]quinoline | Environmental Substance | Unclassified Environmental Substances | 1 |
| 2-Amino-3-methylimidazo(4,5-f)quinoline(IQ) | Therapeutic substance | chemicalcompounds | 1 |
| 2-chloro-5-nitro-N-phenylbenzamide | Therapeutic Substance | Investigational Drug | 1 |
| 2-methoxy esterone | Therapeutic substance | Anti-angiogenic | 1 |
| 3,3-dimethyl-1-butanol | Environmental Substance | Unclassified Environmental Substances | 1 |
| 3,4-Dihydro-5-Methyl-Isoquinolinone | Therapeutic Substance | Investigational Drug | 1 |
| 4-Aminosalicylic Acid | Therapeutic Substance | Approved Drug | 1 |
| 5-fluorodeoxyuridine | Therapeutic Substance | Approved Drug | 1 |
| 6-Mercaptopurine-2?deoxyriboside | Therapeutic Substance | Approved Drug | 1 |
| 6-Mercaptopurine-2deoxyriboside | Therapeutic substance | chemotherapeutic | 1 |
| 7-ethyl-10-hydroxycamptothecin | Therapeutic Substance | Investigational Drug | 1 |
| 7-ethyl-10-hydroxycamptothecin | Therapeutic Substance | Therapeutic Substance | 1 |
| 7-ethyl-10-hydroxycamptothecin(SN-38) | Therapeutic substance | antineoplastic | 1 |
| Abacavir Sulfate | Therapeutic Substance | Approved Drug | 1 |
| Abiraterone | Therapeutic Substance | prostate cancer | 1 |
| Acebutolol | Therapeutic Substance | Approved Drug | 1 |
| Acetaminophen | Therapeutic Substance | Approved Drug | 1 |
| Acetohexamide | Therapeutic Substance | Approved Drug | 1 |
| Acitretin | Therapeutic Substance | Approved Drug | 1 |
| Acrivastine | Therapeutic Substance | Approved Drug | 1 |
| Actinomycin | Therapeutic Substance | Approved Drug | 1 |
| Acyclovir Zovirax | Therapeutic Substance | Approved Drug | 1 |
| Adefovir Dipivoxil | Therapeutic Substance | Approved Drug | 1 |
| Aflatoxin B1 | Environmental Chemicals | Carcinogenic mycotoxins | 1 |
| Albendazole | Therapeutic Substance | Approved Drug | 1 |
| Allopurinol | Therapeutic Substance | Approved Drug | 1 |
| Alosetron | Therapeutic Substance | Approved Drug | 1 |
| Alprenolol | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 1 |
| Alternariaspp. toxins | Environmental Chemicals | n.a. | 1 |
| Ambrisentan | Therapeutic Substance | Approved Drug | 1 |
| Amiloride | Therapeutic Substance | Approved Drug | 1 |
| Aminophylline | Therapeutic Substance | Approved Drug | 1 |
| Amitriptyline | Therapeutic Substance | Approved Drug | 1 |
| Amlodipine | Therapeutic Substance | antihypertensive | 1 |
| Amoxapine | Therapeutic Substance | Approved Drug | 1 |
| Amygdalin | Herbal Substance; Dietary Substance | Medicinal Herbal Compounds; Dietary Compounds | 1 |
| Anthocyanidins | Herbal Substance | Herbal Compounds | 1 |
| Anti-TNF antibobies | Therapeutic Substance | Drug Class | 1 |
| Antibiotic | Therapeutic Substance | Therapeutic Substance | 1 |
| Antibiotic (extensive treatment) | Therapeutic Substance | Drug Class | 1 |
| Antidiabetic drugs | Therapeutic Substance | Drug Class | 1 |
| Antiobiotics | Therapeutic Substance | Drug Class | 1 |
| Apomorphine | Therapeutic Substance | Approved Drug | 1 |
| Aprepitant | Therapeutic Substance | Approved Drug | 1 |
| AQ4N | Therapeutic Substance | Approved Drug; Prodrug | 1 |
| AQ4N | Therapeutic substance | Therapeutic Substance | 1 |
| Arabinoxylan-oligosaccharides | Environmental Substance | Unclassified Environmental Substances | 1 |
| Arbutin | Therapeutic Substance | anti-infective | 1 |
| Aripiprazole | Therapeutic Substance | Approved Drug | 1 |
| Arsenic | Environmental Chemicals | Environmental Substance | 1 |
| Artemether | Therapeutic Substance | Approved Drug | 1 |
| Aryl hydrocarbon receptor activator | Environmental Substance | Industrial Chemicals; Pollutants; Toxic Agents | 1 |
| As toxicity | Environmental Chemicals | n.a. | 1 |
| Asenapine Maleate | Therapeutic Substance | Approved Drug | 1 |
| Aspirin | Therapeutic Substance | Approved Drug | 1 |
| Astragali radix | Herbal Substance | Medicinal Herb | 1 |
| Atazanavir | Therapeutic Substance | Approved Drug | 1 |
| Atorvastatin | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 1 |
| Atorvastatin Calcium | Therapeutic Substance | Approved Drug | 1 |
| Atovaquone | Therapeutic Substance | Approved Drug | 1 |
| Azathioprine | Therapeutic Substance | Approved Drug | 1 |
| Azetirelin | Therapeutic Substance | Approved Drug | 1 |
| Azetirelin | Therapeutic Substance | thyrotropin-releasing hormone (TRH) ana-logue | 1 |
| Azithromycin | Therapeutic Substance | Approved Drug | 1 |
| Azo dyes | Environmental Chemicals | Environmental Substance | 1 |
| Azo dyes | Environmental Substance | Industrial Chemicals; Pollutants | 1 |
| B-GOSr (prebiotic oligosaccharide) | Therapeutic Substance | n.a. | 1 |
| Baicalin | Herbal Substance | anti-inflammatory | 1 |
| Balsalazide | Therapeutic Substance | Approved Drug; Prodrug | 1 |
| Banoxantrone(AQ4N) | Therapeutic substance | chemotherapeutic | 1 |
| Benzbromarone | Therapeutic Substance | Approved Drug | 1 |
| Benzodiazepines | Therapeutic substance | unknown | 1 |
| Benztropine Mesylate | Therapeutic Substance | Approved Drug | 1 |
| Berberine | Herbal Substance | antifungal infections and as antidiarrheal | 1 |
| betaLapachone | Therapeutic Substance | Approved Drug | 1 |
| betaLapachone | Therapeutic substance | chemotherapeutic | 1 |
| Betamethasone | Therapeutic Substance | Approved Drug | 1 |
| Bexarotene | Therapeutic Substance | Approved Drug | 1 |
| BILR355 | Therapeutic Substance | Investigational Drug | 1 |
| Bisoprolol Fumarate | Therapeutic Substance | Approved Drug | 1 |
| Bosentan | Therapeutic Substance | Approved Drug | 1 |
| Bromazepam | Therapeutic Substance | anti-anxiety disorders | 1 |
| Brompheniramine Maleate | Therapeutic Substance | Approved Drug | 1 |
| Bumetanide | Therapeutic Substance | Approved Drug | 1 |
| Buspirone | Therapeutic Substance | Approved Drug | 1 |
| Butorphanol-(+)-Tartrate | Therapeutic Substance | Approved Drug | 1 |
| Butyl paraben | Therapeutic substance | compound | 1 |
| Cabergoline | Therapeutic Substance | Approved Drug | 1 |
| Caffeic acid | Herbal Substance | compound | 1 |
| Caffeic acid | Herbal Substance | Medicinal Herbal Compounds | 1 |
| Caffeic acid | Therapeutic Substance | Dietary Compounds | 1 |
| Caffeine | Therapeutic Substance | Approved Drug | 1 |
| Calcitonin | Therapeutic Substance | Approved Drug | 1 |
| Calcitonin | Therapeutic Substance | calcitonin | 1 |
| Calcitriol | Therapeutic Substance | Approved Drug | 1 |
| Calycosin-7-O-b-D-glucoside | Herbal Substance | Medicinal Herbal Compounds | 1 |
| Camylofine dihydrochloride | Therapeutic Substance | Approved Drug | 1 |
| Candesartan | Therapeutic Substance | Approved Drug | 1 |
| Capsaicin | Therapeutic Substance | Approved Drug | 1 |
| Captopril | Therapeutic Substance | Approved Drug | 1 |
| Carbamazepine | Therapeutic Substance | Approved Drug | 1 |
| Carbidopa | Therapeutic Substance | Approved Drug | 1 |
| Carbinoxamine Maleate | Therapeutic Substance | Approved Drug | 1 |
| Carboplatin | Therapeutic Substance | antineoplastic alkylating | 1 |
| Carnitine | Therapeutic Substance | Dietary Compounds | 1 |
| CB954 | Environmental Substance | Unclassified Environmental Substances | 1 |
| Cefditoren Pivoxil | Therapeutic Substance | Approved Drug | 1 |
| Cefoperazone | Therapeutic Substance | Approved Drug | 1 |
| Cefpodoxime Proxetil | Therapeutic Substance | Approved Drug; Antibiotics | 1 |
| Checkpoint inhibitor therapy | Therapeutic Substance | Drug Class | 1 |
| Checkpoint inhibitor therapy | Therapeutic Substance | Therapeutic Substance | 1 |
| Chenodeoxycholic acid | Herbal Substance | Medicinal Herbal Compounds | 1 |
| Chenodiol | Therapeutic Substance | Approved Drug | 1 |
| Chloramphenicol | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 1 |
| Chloroacetic acid | Therapeutic substance | Antioxidant | 1 |
| Chlorogenic acid | Therapeutic Substance | Antioxidant | 1 |
| Chloroquine Diphosphate | Therapeutic Substance | Approved Drug | 1 |
| Chlorothiazide | Therapeutic Substance | Approved Drug | 1 |
| Chlorpheniramine Maleate | Therapeutic Substance | Approved Drug | 1 |
| Chlorpropamide | Therapeutic Substance | Approved Drug | 1 |
| Chlorthalidone | Therapeutic Substance | Approved Drug | 1 |
| Chlorzoxazone | Therapeutic Substance | Approved Drug | 1 |
| Cholic acid | Herbal Substance | Medicinal Herbal Compounds | 1 |
| Choline | Therapeutic Substance | Dietary Compounds | 1 |
| Choline | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 1 |
| Cianidanol | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 1 |
| Cilostazol | Therapeutic Substance | Approved Drug | 1 |
| Cinacalcet | Therapeutic Substance | Approved Drug | 1 |
| Ciprofloxacin | Therapeutic Substance | Approved Drug; Antibiotics | 1 |
| Cisplatin | Therapeutic Substance | Antitumor | 1 |
| Citalopram | Therapeutic Substance | Approved Drug | 1 |
| Clarithromycin | Therapeutic Substance | Approved Drug | 1 |
| Clemizole | Therapeutic Substance | Approved Drug | 1 |
| Clindamycin | Therapeutic Substance | Approved Drug; Antibiotics | 1 |
| Clobazam | Therapeutic Substance | Approved Drug | 1 |
| Clofazimine | Therapeutic Substance | Approved Drug | 1 |
| Clomiphene Citrate | Therapeutic Substance | Approved Drug | 1 |
| Clomipramine | Therapeutic Substance | Approved Drug | 1 |
| Clopidogrel Hydrogen Sulfate | Therapeutic Substance | Approved Drug | 1 |
| Clozapine | Therapeutic Substance | Approved Drug | 1 |
| Codeine | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 1 |
| Codeine | Therapeutic Substance; Herbal Substance | Therapeutic Substance; Herbal Substance | 1 |
| Colchicine | Therapeutic Substance | Approved Drug | 1 |
| Common azole treatment | Therapeutic Substance | Drug Class | 1 |
| Corticosteroids | Therapeutic Substance | Approved Drug | 1 |
| Cortisone Acetate | Therapeutic Substance | Approved Drug | 1 |
| CpG oligodeoxynucleotides | Therapeutic Substance | oligodeoxynucleotides | 1 |
| CpG-oligonucleotide immunotherapy | Therapeutic Substance | Drug Class | 1 |
| Cromolyn | Therapeutic Substance | Approved Drug | 1 |
| Curcumin | Therapeutic Substance; Herbal Substance | Investigational Drug; Medicinal Herbal Compounds | 1 |
| Cycasin | Therapeutic substance | compound | 1 |
| Cyclosporine A | Therapeutic Substance | Approved Drug | 1 |
| Cyproheptadine | Therapeutic Substance | Approved Drug | 1 |
| Cysteine-S-conjugates of xenobiotics | Environmental Substance | Unclassified Environmental Substances | 1 |
| Daidzin | Therapeutic Substance; Herbal Substance | Therapeutic Substance; Herbal Substance | 1 |
| Dantrolene | Therapeutic Substance | Approved Drug | 1 |
| Dapsone | Therapeutic Substance | Approved Drug | 1 |
| Darifenacin | Therapeutic Substance | Approved Drug | 1 |
| Darunavir | Therapeutic Substance | Approved Drug | 1 |
| Dasatinib | Therapeutic Substance | Therapeutic Substance | 1 |
| Deferasirox | Therapeutic Substance | Approved Drug | 1 |
| Delavirdine Mesylate | Therapeutic Substance | Approved Drug | 1 |
| Deleobuvir | Therapeutic Substance | Investigational Drug | 1 |
| Deleobuvir | Therapeutic Substance | under investigation in clinical trial | 1 |
| Demeclocycline | Therapeutic Substance | Approved Drug | 1 |
| Desipramine | Therapeutic Substance | Approved Drug | 1 |
| Desloratadine | Therapeutic Substance | Approved Drug | 1 |
| Desvenlafaxine Succinate Hydrate | Therapeutic Substance | Approved Drug | 1 |
| Dexamethasone | Therapeutic Substance | Therapeutic Substance | 1 |
| Dexchlorpheniramine Maleate | Therapeutic Substance | Approved Drug | 1 |
| Dextromethorphan | Therapeutic Substance | Approved Drug | 1 |
| Diazepam | Therapeutic Substance | Approved Drug | 1 |
| Diazoxide | Therapeutic Substance | Approved Drug | 1 |
| Dienogest | Therapeutic Substance | Approved Drug | 1 |
| Diflunisal | Therapeutic Substance | Approved Drug | 1 |
| Digoxin | Therapeutic Substance | Approved Drug | 1 |
| Digoxin | Therapeutic Substance | Approved Drug; Prodrug | 1 |
| Dihydrodaidzein | Herbal Substance | Medicinal Herbal Compounds | 1 |
| Dihydroxyphenylalanine (DOPA) | Therapeutic Substance | Approved Drug | 1 |
| Dihydroxyphenylalanine (DOPA) | Therapeutic Substance | Therapeutic Substance | 1 |
| Dimenhydrinate | Therapeutic Substance | Approved Drug | 1 |
| Diphenhydramine | Therapeutic Substance | Approved Drug | 1 |
| Diphenylpyraline | Therapeutic Substance | Approved Drug | 1 |
| Disopyramide | Therapeutic Substance | Approved Drug | 1 |
| Dofetilide | Therapeutic Substance | Approved Drug | 1 |
| Dolasetron | Therapeutic Substance | Approved Drug | 1 |
| Donepezil | Therapeutic Substance | Approved Drug | 1 |
| Doxepin | Therapeutic Substance | Approved Drug | 1 |
| Doxifluridine | Therapeutic Substance | deglycosylation | 1 |
| Doxycycline | Therapeutic Substance | Approved Drug; Antibiotics | 1 |
| Dutasteride | Therapeutic Substance | Approved Drug | 1 |
| Efavirenz | Therapeutic Substance | Approved Drug | 1 |
| Ellagic acid | Therapeutic Substance; Herbal Substance | compound | 1 |
| Eltrombopag | Therapeutic Substance | Approved Drug | 1 |
| Eltrombopag | Therapeutic Substance | Eltrombopag is a thrombopoietin receptor agonist used to treat thrombocytopenia or aplastic anemia associated with various etiologies. | 1 |
| Emtricitabine | Therapeutic Substance | Approved Drug | 1 |
| Enalapril | Therapeutic Substance | Approved Drug | 1 |
| Enalaprilat Maleate | Therapeutic Substance | Approved Drug | 1 |
| Enrofloxacin | Therapeutic Substance | Investigational Drug | 1 |
| Epacadostat | Therapeutic Substance | Epacadostat has been used in trials studying the treatment of HL, Melanoma, Glioblastoma, Mucosal Melanoma, and Ovarian Carcinoma, among others. | 1 |
| Epacadostat | Therapeutic Substance | Investigational Drug | 1 |
| Epicatechin | Therapeutic Substance | Investigational Drug | 1 |
| Epimedium grandiflorum top (flavonoids) | Herbal Substance | Medicinal Herb | 1 |
| Eprosartan Mesylate | Therapeutic Substance | Approved Drug | 1 |
| Erlotinib | Therapeutic Substance | Approved Drug | 1 |
| Escitalopram | Therapeutic Substance | Approved Drug | 1 |
| Esomeprazole Potassium | Therapeutic Substance | Approved Drug | 1 |
| Estradiol | Therapeutic Substance | Approved Drug | 1 |
| Estradiol | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 1 |
| Estradiol | Therapeutic Substance; Herbal Substance | Herbal | 1 |
| Estramustine | Therapeutic Substance | Approved Drug | 1 |
| Estrone | Therapeutic Substance | Approved Drug | 1 |
| Estropipate | Therapeutic Substance | Approved Drug | 1 |
| Ethacrynic Acid | Therapeutic Substance | Approved Drug | 1 |
| Ethanol | Therapeutic Substance | compound | 1 |
| Ethinyl Estradiol | Therapeutic Substance | Approved Drug | 1 |
| Ethionamide | Therapeutic Substance | Approved Drug | 1 |
| Ethoxzolamide | Therapeutic Substance | Approved Drug | 1 |
| Etoposide phosphate | Therapeutic substance | chemotherapeutic | 1 |
| Everolimus | Therapeutic Substance | Approved Drug | 1 |
| Exemestane | Therapeutic Substance | Approved Drug | 1 |
| Ezetimibe | Therapeutic Substance | Lipid modifying agents | 1 |
| Famotidine | Therapeutic Substance | Approved Drug | 1 |
| Famotidine | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 1 |
| Felbamate | Therapeutic Substance | Approved Drug | 1 |
| Felodipine | Therapeutic Substance | Approved Drug | 1 |
| Fenfluramine | Therapeutic Substance | Approved Drug | 1 |
| Fenoprofen Calcium | Therapeutic Substance | Approved Drug | 1 |
| Fexofenadine | Therapeutic Substance | Approved Drug | 1 |
| Fingolimod | Therapeutic Substance | Approved Drug | 1 |
| Flavoxate | Therapeutic Substance | Approved Drug | 1 |
| Flecainide Acetate | Therapeutic Substance | Approved Drug | 1 |
| Floxuridine | Therapeutic Substance | Therapeutic Substance | 1 |
| Flucytosine | Therapeutic Substance | antifungals | 1 |
| Fludarabine | Therapeutic Substance | Approved Drug | 1 |
| Fludrocortisone Acetate | Therapeutic Substance | Approved Drug | 1 |
| Fluoxetine | Therapeutic Substance | Approved Drug | 1 |
| Fluoxetine | Therapeutic Substance; Herbal Substance | inhibitor | 1 |
| Flurbiprofen | Therapeutic Substance | Approved Drug | 1 |
| Flutamide | Therapeutic Substance | Approved Drug | 1 |
| Fluvastatin | Therapeutic Substance | Approved Drug | 1 |
| Formoterol | Therapeutic Substance | Approved Drug | 1 |
| Fosinopril | Therapeutic Substance | Approved Drug | 1 |
| Fostamatinib | Therapeutic Substance | Approved Drug | 1 |
| Furosemide | Therapeutic Substance | Approved Drug | 1 |
| Gabapentin | Therapeutic Substance | Approved Drug | 1 |
| Galantamine | Therapeutic Substance | Approved Drug | 1 |
| Gatifloxacin | Therapeutic Substance | Approved Drug | 1 |
| Gefitinib | Therapeutic Substance | Approved Drug | 1 |
| Gemfibrozil | Therapeutic Substance | Approved Drug | 1 |
| Gemifloxacin | Therapeutic Substance | Approved Drug; Antibiotics | 1 |
| Geniposide | Herbal Substance | Geniposide has significant effects on digestive system, cardiovascular system and central nervous system diseases. Geniposide also has certain anti-inflammatory and soft tissue injury effects. | 1 |
| Gliadin | Therapeutic substance | compound | 1 |
| Glimepiride | Therapeutic Substance | Approved Drug | 1 |
| Glucocorticoids | Therapeutic Substance | Drug Class | 1 |
| Glucuronidated compound | Environmental Substance | Unclassified Environmental Substances | 1 |
| Glyburide | Therapeutic Substance | Approved Drug | 1 |
| Glyceryl trinitrate | Therapeutic Substance | angina pectoris | 1 |
| Glycyrrhizin | Herbal Substance | Medicinal Herbal Compounds | 1 |
| Granisetron | Therapeutic Substance | Approved Drug | 1 |
| Grape Seed Polyphenol Extract (GPSE) | Therapeutic substance | unknown | 1 |
| Griseofulvin | Therapeutic Substance | Approved Drug | 1 |
| Guanabenz Acetate | Therapeutic Substance | Approved Drug | 1 |
| Guanfacine | Therapeutic Substance | Approved Drug | 1 |
| Haloperidol | Therapeutic Substance | Approved Drug | 1 |
| Hesperidin | Therapeutic Substance; Herbal Substance | anti-allergy | 1 |
| Hespesidin | Therapeutic substance | Therapeutic Substance; Herbal Substance | 1 |
| Heterocyclic amine 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) | Environmental Substance | Unclassified Environmental Substances | 1 |
| Heterocyclic amines | Environmental Substance | Unclassified Environmental Substances | 1 |
| Heterocyclic aromaticamines (HAAs) | Therapeutic substance | Carcinogenic agents | 1 |
| Hippuric acid | Environmental Chemicals | Environmental Substance | 1 |
| Hippuric acid | Environmental Substance | Industrial Chemicals; Pollutants; Toxic Agents | 1 |
| Hydralazine | Therapeutic Substance | Approved Drug | 1 |
| Hydrazine | Environmental Substance | Industrial Chemicals; Medicinal chemicals | 1 |
| Hydrochlorothiazide | Therapeutic Substance | Approved Drug | 1 |
| Hydrocortisone | Therapeutic Substance | Approved Drug | 1 |
| Hydroflumethiazide | Therapeutic Substance | Approved Drug | 1 |
| Hydroxychloroquine Sulfate | Therapeutic Substance | Approved Drug | 1 |
| Hydroxyzine Dihydrochloride | Therapeutic Substance | Approved Drug | 1 |
| Hypochlorite | Therapeutic Substance | Approved Drug | 1 |
| Ibuprofen | Therapeutic Substance | Approved Drug | 1 |
| Idarubicin | Therapeutic Substance | Approved Drug | 1 |
| Iloperidone | Therapeutic Substance | Approved Drug | 1 |
| Imatinib | Therapeutic Substance | Therapeutic Substance | 1 |
| Imipramine | Therapeutic Substance | Approved Drug | 1 |
| Incretin | Environmental Substance | Human Metabolite | 1 |
| Indapamide | Therapeutic Substance | Approved Drug | 1 |
| Indicine N-oxide | Therapeutic substance | compound | 1 |
| Indigestible polysaccharides | Therapeutic Substance | Dietary Compounds | 1 |
| Indinavir | Therapeutic Substance | Approved Drug | 1 |
| Indole | Environmental Substance | Metabolite | 1 |
| Indole | Therapeutic Substance; Herbal Substance | Investigational Drug | 1 |
| Insulin | Therapeutic Substance | Blood glucose control | 1 |
| Insulin human | Therapeutic Substance | Approved Drug | 1 |
| Ipilimumab | Therapeutic Substance | Approved Drug | 1 |
| Ipsalazide | Therapeutic Substance | Approved Drug | 1 |
| Ipsalazide | Therapeutic Substance | Approved Drug; Prodrug | 1 |
| Irsogladine maleate | Therapeutic Substance | Approved Drug | 1 |
| Isocarboxazid | Therapeutic Substance | Approved Drug | 1 |
| Isosorbide dinitrate | Therapeutic Substance; Herbal Substance | organic nitrates for the treatment of angina pec-toris | 1 |
| Isradipine | Therapeutic Substance | Approved Drug | 1 |
| Kanamycin | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 1 |
| Ketoconazole | Therapeutic Substance | Approved Drug | 1 |
| Ketoprofen | Therapeutic Substance | Approved Drug | 1 |
| Ketoprofen | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 1 |
| Ketotifen Fumarate | Therapeutic Substance | Approved Drug | 1 |
| L-carnitine | Therapeutic Substance | compound | 1 |
| L-tryptophan | Therapeutic Substance | amino acid | 1 |
| L-tyrosine | Therapeutic Substance | Dietary Compounds | 1 |
| Labetalol | Therapeutic Substance | Approved Drug | 1 |
| Lacosamide | Therapeutic Substance | Approved Drug | 1 |
| Lamivudine | Therapeutic Substance | Approved Drug | 1 |
| Lamotrigine | Therapeutic Substance | Approved Drug | 1 |
| Lansoprazole | Therapeutic Substance | Approved Drug | 1 |
| Lapatinib Ditosylate | Therapeutic Substance | Approved Drug | 1 |
| Leflunomide | Therapeutic Substance | Approved Drug | 1 |
| Lenalidomide | Therapeutic Substance | Approved Drug | 1 |
| Letrozole | Therapeutic Substance | Approved Drug | 1 |
| Levocarnitine | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 1 |
| Levocarnitine | Therapeutic Substance; Herbal Substance | Herbal | 1 |
| Levocetirizine Dihydrochloride | Therapeutic Substance | Approved Drug | 1 |
| Levofloxacin | Therapeutic Substance | Approved Drug; Antibiotics | 1 |
| Levosimendan | Therapeutic Substance | Approved Drug | 1 |
| Levosimendan | Therapeutic Substance | Levosimendan is used to manage acutely decompensated congestive heart failur | 1 |
| Lincomycin | Therapeutic Substance | Approved Drug | 1 |
| Linezolid | Therapeutic Substance | Approved Drug | 1 |
| Linoleic acid | Herbal Substance | unknown | 1 |
| Liraglutide | Therapeutic Substance | Approved Drug | 1 |
| Lofexidine | Therapeutic Substance | Approved Drug | 1 |
| Loperamide | Therapeutic Substance | Approved Drug | 1 |
| Loperamide | Therapeutic Substance | Approved Drug; Prodrug | 1 |
| Loperamide oxide | Therapeutic Substance | Antiiarrheal medication | 1 |
| Loperamide oxide | Therapeutic Substance | Investigational Drug | 1 |
| Lopinavir | Therapeutic Substance | Approved Drug | 1 |
| Loratadine | Therapeutic Substance | Approved Drug | 1 |
| Lorazepam | Therapeutic Substance | Approved Drug | 1 |
| Losartan Potassium | Therapeutic Substance | Approved Drug | 1 |
| Lovastatin | Therapeutic Substance | Approved Drug | 1 |
| Lovastatin related compounds | Therapeutic Substance | n.a. | 1 |
| Lovastatine | Therapeutic Substance | Hypolipidemics | 1 |
| Loxapine Succinate | Therapeutic Substance | Approved Drug | 1 |
| Maprotiline | Therapeutic Substance | Approved Drug | 1 |
| Maraviroc | Therapeutic Substance | Approved Drug | 1 |
| Meclizine Dihydrochloride | Therapeutic Substance | Approved Drug | 1 |
| Meclofenamate | Therapeutic Substance | Approved Drug | 1 |
| Medroxyprogesterone Acetate | Therapeutic substance | hormone | 1 |
| Mefenamic Acid | Therapeutic Substance | Approved Drug | 1 |
| Mefenamic Acid | Therapeutic substance | NSAID | 1 |
| Meloxicam | Therapeutic Substance | Approved Drug | 1 |
| Menadione | Therapeutic Substance | Approved Drug | 1 |
| Mepenzolate Bromide | Therapeutic Substance | Approved Drug | 1 |
| Meprobamate | Therapeutic Substance | Approved Drug | 1 |
| Mesalazines | Therapeutic Substance | Approved Drug | 1 |
| Mestranol | Therapeutic Substance | Approved Drug | 1 |
| Metamfetamine | Therapeutic Substance | psychostimulant and sympathomimetic | 1 |
| Metaproterenol Hemisulfate | Therapeutic Substance | Approved Drug | 1 |
| Metformin | Therapeutic Substance | Approved Drug | 1 |
| Methazolamide | Therapeutic Substance | Approved Drug | 1 |
| Methenamine Hippurate | Therapeutic Substance | Approved Drug | 1 |
| Methimazole | Therapeutic Substance | Approved Drug | 1 |
| Methocarbamol | Therapeutic Substance | Approved Drug | 1 |
| Methoxsalen | Therapeutic Substance | Approved Drug | 1 |
| Methylergonovine Maleate | Therapeutic Substance | Approved Drug | 1 |
| Methylmercuric chloride | Therapeutic substance | compound | 1 |
| Methylmercury | Environmental Chemicals | compound | 1 |
| Methylmercury | Environmental Substance | Industrial Chemicals; Pollutants; Toxic Agents | 1 |
| Methylprednisolone | Therapeutic Substance | Approved Drug | 1 |
| Metitepine maleate | Therapeutic Substance | Approved Drug | 1 |
| Metoclopramide | Therapeutic Substance | Approved Drug | 1 |
| Metolazone | Therapeutic Substance | Approved Drug | 1 |
| Metoprolol | Therapeutic Substance | beta-blocker | 1 |
| Metronidazole | Therapeutic Substance | Approved Drug | 1 |
| Metyrapone | Therapeutic Substance | Approved Drug | 1 |
| Mexiletine | Therapeutic Substance | Approved Drug | 1 |
| Miconazole | Therapeutic Substance | Approved Drug | 1 |
| Milnacipran | Therapeutic Substance | Approved Drug | 1 |
| Minocycline | Therapeutic Substance | Approved Drug; Antibiotics | 1 |
| Mirtazapine | Therapeutic Substance | Approved Drug | 1 |
| Misonidazole | Therapeutic Substance | Investigational Drug | 1 |
| Misoprostol | Therapeutic Substance | Approved Drug | 1 |
| Mitomycin C | Therapeutic Substance | Approved Drug | 1 |
| Mitotane | Therapeutic Substance | Approved Drug | 1 |
| Mitoxantrone | Therapeutic Substance | Approved Drug | 1 |
| Modafinil | Therapeutic Substance | Approved Drug | 1 |
| Moexipril | Therapeutic Substance | Approved Drug | 1 |
| Montelukast | Therapeutic Substance | Approved Drug | 1 |
| Morphine | Therapeutic Substance; Herbal Substance | opioid agonist | 1 |
| Moxifloxacin | Therapeutic Substance | Approved Drug | 1 |
| Mycophenolic Acid | Therapeutic Substance | Approved Drug | 1 |
| Nabumetone | Therapeutic Substance | NSAID | 1 |
| Nadolol | Therapeutic Substance | Approved Drug | 1 |
| Naltrexone | Therapeutic Substance | Approved Drug | 1 |
| Naproxen | Therapeutic Substance | Approved Drug | 1 |
| Naratriptan | Therapeutic Substance | Approved Drug | 1 |
| Naringenin | Therapeutic Substance; Herbal Substance | Investigational Drug; Medicinal Herbal Compounds | 1 |
| NaringNnin | Therapeutic substance | compound | 1 |
| Nebivolol | Therapeutic Substance | Approved Drug | 1 |
| Nefazodone | Therapeutic Substance | Approved Drug | 1 |
| Nelfinavir Mesylate | Therapeutic Substance | Approved Drug | 1 |
| Neomycin | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 1 |
| Neoprontosil | Therapeutic Substance | antinfective | 1 |
| Neoprontosil | Therapeutic Substance | Approved Drug | 1 |
| Nicardipine | Therapeutic Substance | Approved Drug | 1 |
| Nifedipine | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 1 |
| Nifedipine | Therapeutic Substance; Herbal Substance | calcium channel blocker | 1 |
| Nilutamide | Therapeutic Substance | Approved Drug | 1 |
| Nimodipine | Therapeutic Substance | Approved Drug | 1 |
| Nisoldipine | Therapeutic Substance | Approved Drug | 1 |
| Nitisinone | Therapeutic Substance | Approved Drug | 1 |
| Nitrobenzodiazepine | Therapeutic Substance | Drug Class | 1 |
| Nitrofurantoin | Therapeutic Substance | Approved Drug | 1 |
| Nitroglycerin | Therapeutic Substance | Approved Drug | 1 |
| Nitroglycerin | Therapeutic Substance | Therapeutic Substance | 1 |
| Nitroglycerin(glyceryl trinitrate) | Therapeutic substance | angina pectoris | 1 |
| Nivolumab | Therapeutic Substance | Anticancer | 1 |
| Nizatidine | Therapeutic Substance | antiulcerotics | 1 |
| Nortriptyline | Therapeutic Substance | Approved Drug | 1 |
| Nystatin | Therapeutic Substance | Approved Drug | 1 |
| Ochratoxin A | Environmental Chemicals | compound | 1 |
| Ofloxacin | Therapeutic Substance | Approved Drug | 1 |
| Olmesartan | Therapeutic Substance | Approved Drug | 1 |
| Olopatadine | Therapeutic Substance | Approved Drug | 1 |
| Olsalazine | Therapeutic Substance | Approved Drug; Prodrug | 1 |
| Ondansetron | Therapeutic Substance | Approved Drug | 1 |
| Orphenadrine citrate | Therapeutic Substance | Approved Drug | 1 |
| Oseltamivir Phosphate | Therapeutic Substance | Approved Drug | 1 |
| Oxaliplatin | Therapeutic Substance | Approved Drug | 1 |
| Oxazepam | Therapeutic Substance | Approved Drug | 1 |
| Oxtriphylline | Therapeutic Substance | Approved Drug | 1 |
| Oxytetracycline | Therapeutic Substance | Approved Drug | 1 |
| Palonosetron | Therapeutic Substance | Approved Drug | 1 |
| Pantoprazole | Therapeutic Substance | Approved Drug | 1 |
| Papaverine | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 1 |
| Paracetamol | Therapeutic substance | first-line therapy in pain | 1 |
| Pazopanib | Therapeutic Substance | Approved Drug | 1 |
| Pectin | Herbal Substance | Medicinal Herbal Compounds | 1 |
| Pedunculagin | Herbal Substance | Medicinal Herbal Compounds | 1 |
| Pemirolast Potassium | Therapeutic Substance | Approved Drug | 1 |
| Pentobarbital | Therapeutic Substance | Approved Drug | 1 |
| Pentoxifylline | Therapeutic Substance | Approved Drug | 1 |
| Perindopril Erbumine | Therapeutic Substance | Approved Drug | 1 |
| Perphenazine | Therapeutic Substance | Approved Drug | 1 |
| Persistent organic pollutant | Environmental Substance | Industrial Chemicals; Pollutants | 1 |
| Phenacetin | Therapeutic Substance | analgesic | 1 |
| Phenacetin | Therapeutic Substance | Approved Drug (Withdrawn) | 1 |
| Phenoxybenzamine | Therapeutic Substance | Approved Drug | 1 |
| Phenylephrine | Therapeutic Substance | Approved Drug | 1 |
| Phenytoin | Therapeutic Substance | Approved Drug | 1 |
| Phosphate or sulfate ester prodrugs | Therapeutic Substance | Drug Class | 1 |
| Phosphatidylcholine | Therapeutic substance | compound | 1 |
| Phospholipase A2 | Therapeutic substance | unknown | 1 |
| Physical activity | Environmental Substance | Unclassified Environmental Substances | 1 |
| Pilocarpine | Therapeutic Substance | Approved Drug | 1 |
| Piroxicam | Therapeutic Substance | Approved Drug | 1 |
| Pitavastatin Calcium | Therapeutic Substance | Approved Drug | 1 |
| Plant-derived glycosides(amygdalin) | Herbal Substance | Medicinal Herbal Compounds | 1 |
| Platinum chemotherapy | Therapeutic Substance | Drug Class | 1 |
| Polyaromatic compounds | Environmental Substance | Unclassified Environmental Substances | 1 |
| Polychemotherapy | Therapeutic Substance | Drug Class | 1 |
| Polyphenols | Herbal Substance; Dietary Substance | Medicinal Herbal Compounds; Dietary Compounds | 1 |
| Polysorbate 80 | Therapeutic Substance | Approved Drug | 1 |
| Polysorbate 81 | Environmental Substance | Industrial Chemicals; Pollutants | 1 |
| polysorbate-80 | Environmental Chemicals | n.a. | 1 |
| Posaconazole | Therapeutic Substance | Approved Drug | 1 |
| Potassium oxonate | Environmental Chemicals | unknown | 1 |
| Potassium oxonate | Environmental Substance | Unclassified Environmental Substances | 1 |
| Pramipexole Dihydrochloride Monohydrate | Therapeutic Substance | Approved Drug | 1 |
| Prasugrel | Therapeutic Substance | Approved Drug | 1 |
| Pravastatin | Therapeutic Substance | Approved Drug | 1 |
| Praziquantel | Therapeutic Substance | Approved Drug | 1 |
| Prazosin | Therapeutic Substance | Approved Drug | 1 |
| Prednisolone | Therapeutic Substance | Approved Drug | 1 |
| Prednisone | Therapeutic Substance | Approved Drug | 1 |
| Primidone | Therapeutic Substance | Approved Drug | 1 |
| Probenecid | Therapeutic Substance | Approved Drug | 1 |
| Procainamide | Therapeutic Substance | Approved Drug | 1 |
| Progesterone | Therapeutic Substance | Approved Drug | 1 |
| Progesterone | Therapeutic substance | hormone | 1 |
| Promethazine | Therapeutic Substance | Approved Drug | 1 |
| Prontosil | Therapeutic Substance | antibacterial | 1 |
| Prontosil | Therapeutic Substance | Approved Drug | 1 |
| Propafenone | Therapeutic Substance | Approved Drug | 1 |
| Propranolol | Therapeutic Substance | Approved Drug | 1 |
| Propylthiouracil | Therapeutic Substance | Approved Drug | 1 |
| Protriptyline | Therapeutic Substance | Approved Drug | 1 |
| Puerarin | Therapeutic Substance; Herbal Substance | Herbal | 1 |
| Pyrazinamide | Therapeutic Substance | Approved Drug | 1 |
| Pyrimethamine | Therapeutic Substance | Approved Drug | 1 |
| Quetiapine Fumarate | Therapeutic Substance | Approved Drug | 1 |
| Quinidine | Therapeutic Substance | Approved Drug | 1 |
| Quinine | Therapeutic Substance | Approved Drug | 1 |
| Rabeprazole | Therapeutic Substance | Approved Drug | 1 |
| Radiation sensitizer misonidazole | Therapeutic Substance | n.a. | 1 |
| Raloxifene | Therapeutic Substance | Approved Drug | 1 |
| Raltegravir | Therapeutic Substance | Approved Drug | 1 |
| Ranolazine | Therapeutic Substance | Approved Drug | 1 |
| Rasagiline Mesylate | Therapeutic Substance | Approved Drug | 1 |
| Reserpine | Therapeutic Substance | Approved Drug | 1 |
| Resveratrol | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 1 |
| Rifabutin | Therapeutic Substance | Approved Drug | 1 |
| Rifampin | Therapeutic Substance | Approved Drug | 1 |
| Rifapentine | Therapeutic Substance | Approved Drug | 1 |
| Rimantadine | Therapeutic Substance | Approved Drug | 1 |
| Rivastigmine Tartrate | Therapeutic Substance | Approved Drug | 1 |
| Rizatriptan benzoate | Therapeutic Substance | Approved Drug | 1 |
| Ropinirole | Therapeutic Substance | Approved Drug | 1 |
| Rosiglitazone | Therapeutic Substance | Approved Drug | 1 |
| Rosuvastatin | Therapeutic Substance | lipid-lowering drug | 1 |
| Rosuvastatin Calcium | Therapeutic Substance | Approved Drug | 1 |
| Rufinamide | Therapeutic Substance | Approved Drug | 1 |
| Salicin | Therapeutic Substance | compound | 1 |
| Saponins | Therapeutic substance | compound | 1 |
| Saquinavir Mesylate | Therapeutic Substance | Approved Drug | 1 |
| Saxagliptin | Therapeutic Substance | Approved Drug | 1 |
| Scopolamine | Therapeutic Substance | Approved Drug | 1 |
| Selegiline | Therapeutic Substance | Approved Drug | 1 |
| Sennosides | Therapeutic Substance | Investigational Drug | 1 |
| Sennosides | Therapeutic Substance | Therapeutic Substance | 1 |
| Sertraline | Therapeutic Substance | Approved Drug | 1 |
| Shikonin | Herbal Substance | Medicinal Herbal Compounds | 1 |
| Simvastatin | Therapeutic Substance | Approved Drug | 1 |
| Sitagliptin | Therapeutic Substance | Approved Drug | 1 |
| Sitagliptin Phosphate | Therapeutic Substance | Approved Drug | 1 |
| Sodium picosulfate | Therapeutic Substance | laxative | 1 |
| Sorafenib Tosylate | Therapeutic Substance | Approved Drug | 1 |
| Soy-derived phytoestrogens | Therapeutic substance | Xeno-estrogens | 1 |
| Spironolactone | Therapeutic Substance | Approved Drug | 1 |
| Streptomycin | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 1 |
| Streptonegrin | Therapeutic Substance | Approved Drug | 1 |
| succinylsulfathiazole | Therapeutic substance | antibacterial | 1 |
| Sulfadiazine | Therapeutic Substance | antibiotic | 1 |
| Sulfamethoxazole | Therapeutic Substance | Approved Drug | 1 |
| Sulfapyridine | Therapeutic Substance | Approved Drug | 1 |
| Sulfinpyrazone | Therapeutic Substance | anti-inflammatory | 1 |
| Sulfonamide antibiotics | Therapeutic Substance | Drug Class | 1 |
| Sulfotransferase | Therapeutic substance | enzyme | 1 |
| Sulfoxide | Environmental Substance | Unclassified Environmental Substances | 1 |
| Sulindac sulfide | Therapeutic Substance; Environmental Substance | Approved Drug | 1 |
| Sulpiride | Therapeutic Substance | Approved Drug | 1 |
| Tacrine | Therapeutic Substance | Approved Drug | 1 |
| Tacrolimus | Therapeutic Substance | Approved Drug | 1 |
| Tacrolimus | Therapeutic Substance; Herbal Substance | reduce the activity of the patient's immune system | 1 |
| Tamsulosin | Therapeutic Substance | Approved Drug | 1 |
| Taurine conjugated bile acid | Environmental Chemicals | Environmental Substance | 1 |
| Taurine conjugated bile acid | Environmental Substance | Human Metabolite | 1 |
| Telbivudine | Therapeutic Substance | Approved Drug | 1 |
| Telithromycin | Therapeutic Substance | Approved Drug; Antibiotics | 1 |
| Temazepam | Therapeutic Substance | Approved Drug | 1 |
| Tenofovir | Therapeutic Substance | Investigational Drug | 1 |
| Terazosin | Therapeutic Substance | Approved Drug | 1 |
| Terbinafine | Therapeutic Substance | Approved Drug | 1 |
| Terbutaline | Therapeutic Substance | Approved Drug | 1 |
| Tetrabenazine | Therapeutic Substance | Approved Drug | 1 |
| Thalidomide | Therapeutic Substance | Approved Drug | 1 |
| Theophylline | Therapeutic Substance | Approved Drug | 1 |
| Thiazolidinediones | Therapeutic Substance | Drug Class | 1 |
| Thioguanine | Therapeutic Substance | Approved Drug | 1 |
| Thioridazine | Therapeutic Substance | Approved Drug | 1 |
| Tiagabine | Therapeutic Substance | Approved Drug | 1 |
| Ticlopidine | Therapeutic Substance | Approved Drug | 1 |
| Tizanidine | Therapeutic Substance | Approved Drug | 1 |
| TMAO | Environmental Substance | Human Metabolite | 1 |
| Tolbutamide | Therapeutic Substance | Approved Drug | 1 |
| Tolcapone | Therapeutic Substance | Approved Drug | 1 |
| Tolmetin sodium dihydrate | Therapeutic Substance | Approved Drug | 1 |
| Tolterodine Tartrate | Therapeutic Substance | Approved Drug | 1 |
| Tolvaptan | Therapeutic Substance | Approved Drug | 1 |
| Topiramate | Therapeutic Substance | Approved Drug | 1 |
| Topotecan | Therapeutic Substance | Approved Drug | 1 |
| Toremifene Base | Therapeutic Substance | Approved Drug | 1 |
| Torsemide | Therapeutic Substance | Approved Drug | 1 |
| Tramadol | Therapeutic Substance | Approved Drug | 1 |
| Tranylcypromine Hemisulfate | Therapeutic Substance | Approved Drug | 1 |
| Trazodone | Therapeutic Substance | Approved Drug | 1 |
| Triamcinolone Acetonide | Therapeutic Substance | Approved Drug | 1 |
| Triamterene | Therapeutic Substance | Approved Drug | 1 |
| Triazolam | Therapeutic Substance | Approved Drug | 1 |
| Trifluoperazine | Therapeutic Substance | Approved Drug | 1 |
| Trimetazidine dihydrochloride | Therapeutic Substance | Approved Drug | 1 |
| Trimethobenzamide | Therapeutic Substance | Approved Drug | 1 |
| Trimethoprim | Therapeutic Substance | Approved Drug | 1 |
| Trimipramine Maleate | Therapeutic Substance | Approved Drug | 1 |
| Trospium Chloride | Therapeutic Substance | Approved Drug | 1 |
| Tryptophan | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 1 |
| Ursodiol | Therapeutic Substance | Approved Drug | 1 |
| Valacyclovir | Therapeutic Substance | Approved Drug | 1 |
| Vardenafil | Therapeutic Substance | Approved Drug | 1 |
| Venlafaxine | Therapeutic Substance | Approved Drug | 1 |
| Verapamil | Therapeutic Substance | Approved Drug | 1 |
| Verapamil | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 1 |
| Vinblastine | Therapeutic Substance | Approved Drug | 1 |
| Vinorelbine | Therapeutic Substance | Approved Drug | 1 |
| Voglibose | Therapeutic Substance | Investigational Drug | 1 |
| Vorinostat | Therapeutic Substance | Approved Drug | 1 |
| Warfarin | Therapeutic Substance | Approved Drug | 1 |
| Wognoside | Herbal Substance | Medicinal Herbal Compounds | 1 |
| Xylose | Therapeutic Substance | nutritional usage | 1 |
| Zafirlukast | Therapeutic Substance | Approved Drug | 1 |
| Zearalenone | Therapeutic substance | compound | 1 |
| Zileuton | Therapeutic Substance | Approved Drug | 1 |
| Ziprasidone hydrochloride | Therapeutic Substance | Approved Drug | 1 |
| Zolmitriptan | Therapeutic Substance | Approved Drug | 1 |
| Substance Name | Substance Category | Substance Subcategory | Associated Microbe Count |
|---|---|---|---|
| Metformin | Therapeutic Substance | Approved Drug | 189 |
| Chloramphenicol | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 38 |
| Chlorhexidine | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 38 |
| Chlortetracycline hydrochloride | Therapeutic Substance | Approved Drug | 38 |
| Demeclocycline hydrochloride | Therapeutic Substance | Approved Drug | 38 |
| Doxycycline hydrochloride | Therapeutic Substance | Approved Drug | 38 |
| Florfenicol | Therapeutic Substance | Approved Drug (veterinary medicine) | 38 |
| Meclocycline sulfosalicylate | Therapeutic Substance | Approved Drug | 38 |
| Methacycline hydrochloride | Therapeutic Substance | Approved Drug | 38 |
| Minocycline hydrochloride | Therapeutic Substance | Approved Drug | 38 |
| Rifabutin | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 38 |
| Tosufloxacin hydrochloride | Therapeutic Substance | Approved Drug | 38 |
| Alexidine dihydrochloride | Therapeutic Substance | Approved Drug | 37 |
| Azithromycin | Therapeutic Substance | Approved Drug | 37 |
| Carbadox | Therapeutic Substance | Approved Drug (veterinary medicine) | 37 |
| Ciprofloxacin hydrochloride monohydrate | Therapeutic Substance | Approved Drug | 37 |
| Clarithromycin | Therapeutic Substance | Approved Drug | 37 |
| Clinafloxacin | Therapeutic Substance | Approved Drug | 37 |
| Clindamycin hydrochloride | Therapeutic Substance | Approved Drug | 37 |
| Furaltadone hydrochloride | Therapeutic Substance | Approved Drug (veterinary medicine) | 37 |
| Furazolidone | Therapeutic Substance | Approved Drug | 37 |
| Linezolid | Therapeutic Substance | Approved Drug | 37 |
| Moxifloxacin | Therapeutic Substance | Approved Drug | 37 |
| Niridazole | Therapeutic Substance | Approved Drug | 37 |
| Oxytetracycline dihydrate | Therapeutic Substance | Approved Drug | 37 |
| Rifampicin | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 37 |
| Rifapentine | Therapeutic Substance | Approved Drug | 37 |
| Rifaximin | Therapeutic Substance | Approved Drug | 37 |
| Tetracycline hydrochloride | Therapeutic Substance | Approved Drug | 37 |
| Thiamphenicol | Therapeutic Substance | Approved Drug | 37 |
| Benzylpenicillin sodium | Therapeutic Substance | Approved Drug | 36 |
| Gatifloxacin | Therapeutic Substance | Approved Drug | 36 |
| Hexachlorophene | Therapeutic Substance | Approved Drug | 36 |
| Nadifloxacin | Therapeutic Substance | Approved Drug | 36 |
| Nifuroxazide | Therapeutic Substance | Approved Drug | 36 |
| Piperacillin sodium salt | Therapeutic Substance | Approved Drug | 36 |
| Sarafloxacin | Therapeutic Substance | Approved Drug | 36 |
| Tylosin | Therapeutic Substance; Herbal Substance | Approved Drug (veterinary medicine); Medicinal Herbal Compounds | 36 |
| Amoxicillin | Therapeutic Substance | Approved Drug | 35 |
| Benzethonium chloride | Therapeutic Substance | Approved Drug | 35 |
| Cefazolin sodium salt | Therapeutic Substance | Approved Drug | 35 |
| Erythromycin | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 35 |
| Josamycin | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 35 |
| Lincomycin hydrochloride | Therapeutic Substance | Approved Drug | 35 |
| Meropenem | Therapeutic Substance | Approved Drug | 35 |
| Niclosamide | Therapeutic Substance | Approved Drug | 35 |
| Novobiocin sodium salt | Therapeutic Substance | Approved Drug (veterinary medicine) | 35 |
| Proton pump inhibitors | Therapeutic Substance | Drug Class | 35 |
| Roxithromycin | Therapeutic Substance | Approved Drug | 35 |
| Spiramycin | Therapeutic Substance | Approved Drug | 35 |
| Thimerosal | Therapeutic Substance | Approved Drug | 35 |
| Ampicillin trihydrate | Therapeutic Substance | Approved Drug | 34 |
| Auranofin | Therapeutic Substance | Approved Drug | 34 |
| Cefoperazone dihydrate | Therapeutic Substance | Approved Drug | 34 |
| Cefotaxime sodium salt | Therapeutic Substance | Approved Drug | 34 |
| Closantel | Therapeutic Substance | Approved Drug (veterinary medicine) | 34 |
| Dirithromycin | Therapeutic Substance | Approved Drug | 34 |
| Fusidic acid sodium salt | Therapeutic Substance | Approved Drug | 34 |
| Nitrofural | Therapeutic Substance | Approved Drug | 34 |
| Thiostrepton | Therapeutic Substance | Approved Drug (veterinary medicine) | 34 |
| Ticarcillin sodium | Therapeutic Substance | Approved Drug | 34 |
| Benzathine benzylpenicillin | Therapeutic Substance | Approved Drug | 33 |
| Methyl benzethonium chloride | Therapeutic Substance | Approved Drug | 33 |
| Monensin sodium salt | Therapeutic Substance | Approved Drug (veterinary medicine) | 33 |
| Ronidazole | Therapeutic Substance | Approved Drug (veterinary medicine) | 33 |
| Talampicillin hydrochloride | Therapeutic Substance | Approved Drug | 33 |
| Troleandomycin | Therapeutic Substance | Approved Drug | 33 |
| Cefdinir | Therapeutic Substance | Approved Drug | 32 |
| Cefoxitin sodium salt | Therapeutic Substance | Approved Drug | 32 |
| Cephalothin sodium salt | Therapeutic Substance | Approved Drug | 32 |
| Diacerein | Therapeutic Substance | Approved Drug | 32 |
| Imipenem | Therapeutic Substance | Approved Drug | 32 |
| Nifurtimox | Therapeutic Substance | Approved Drug | 32 |
| Phenethicillin potassium salt | Therapeutic Substance | Approved Drug | 32 |
| Sparfloxacin | Therapeutic Substance | Approved Drug | 32 |
| Tinidazole | Therapeutic Substance | Approved Drug | 32 |
| Amoxicillin | Therapeutic Substance | Approved Drug; Antibiotics | 31 |
| Ceforanide | Therapeutic Substance | Approved Drug | 31 |
| Chloroxine | Therapeutic Substance | Approved Drug | 31 |
| Ciprofloxacin | Therapeutic Substance | Approved Drug; Antibiotics | 31 |
| Ebselen | Therapeutic Substance | Investigational Drug | 31 |
| Metronidazole | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 31 |
| Moxalactam disodium salt | Therapeutic Substance | Approved Drug | 31 |
| Ornidazole | Therapeutic Substance | Approved Drug | 31 |
| Pentamidine isethionate | Therapeutic Substance | Approved Drug | 31 |
| Rufloxacin | Therapeutic Substance | Approved Drug | 31 |
| Secnidazole | Therapeutic Substance | Approved Drug | 31 |
| Azlocillin sodium salt | Therapeutic Substance | Approved Drug | 30 |
| Bacitracin | Therapeutic Substance | Approved Drug | 30 |
| Cefepime hydrochloride | Therapeutic Substance | Approved Drug | 30 |
| Cefuroxime sodium salt | Therapeutic Substance | Approved Drug | 30 |
| Cyclophosphamide | Therapeutic Substance | Approved Drug | 30 |
| Daunorubicin hydrochloride | Therapeutic Substance | Approved Drug | 30 |
| Merbromin | Therapeutic Substance | Approved Drug | 30 |
| Nitrofurantoin | Therapeutic Substance | Approved Drug | 30 |
| Vancomycin hydrochloride | Therapeutic Substance | Approved Drug | 30 |
| 5-fluorouracil | Therapeutic Substance | Approved Drug | 29 |
| Arsenic | Environmental Substance | Heavy Metals; Toxic Agents | 29 |
| Cefotetan | Therapeutic Substance | Approved Drug | 29 |
| Clindamycin | Therapeutic Substance | Approved Drug; Antibiotics | 29 |
| Clioquinol | Therapeutic Substance | Approved Drug | 29 |
| Dicloxacillin sodium salt hydrate | Therapeutic Substance | Approved Drug | 29 |
| Bisphenol A | Environmental Substance | Industrial Compounds; Bisphenols | 28 |
| Cadmium | Environmental Substance | Heavy Metals; Toxic Agents | 28 |
| Cefmetazole sodium salt | Therapeutic Substance | Approved Drug | 28 |
| Cefotiam hydrochloride | Therapeutic Substance | Approved Drug | 28 |
| Clotrimazole | Therapeutic Substance | Approved Drug | 28 |
| Dequalinium dichloride | Therapeutic Substance | Approved Drug | 28 |
| Isoconazole | Therapeutic Substance | Approved Drug | 28 |
| Triclosan | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 28 |
| Flucloxacillin sodium | Therapeutic Substance | Approved Drug | 27 |
| Miconazole | Therapeutic Substance | Approved Drug | 27 |
| Benzbromarone | Therapeutic Substance | Approved Drug | 26 |
| Ceftazidime pentahydrate | Therapeutic Substance | Approved Drug | 26 |
| Cloxacillin sodium salt | Therapeutic Substance | Approved Drug | 26 |
| Enoxacin | Therapeutic Substance | Approved Drug | 26 |
| Glyphosate | Environmental Substance | Pesticides | 26 |
| Loracarbef | Therapeutic Substance | Approved Drug | 26 |
| Bacampicillin hydrochloride | Therapeutic Substance | Approved Drug | 25 |
| Cefoperazone | Therapeutic Substance | Approved Drug; Antibiotics | 25 |
| Chlorpyrifos | Environmental Substance | Pesticides | 25 |
| Clofazimine | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 25 |
| Nafcillin sodium salt monohydrate | Therapeutic Substance | Approved Drug | 25 |
| Oxacillin sodium | Therapeutic Substance | Approved Drug | 25 |
| Oxethazaine | Therapeutic Substance | Approved Drug | 25 |
| Tioconazole | Therapeutic Substance | Approved Drug | 25 |
| Cefixime | Therapeutic Substance | Approved Drug | 24 |
| Econazole nitrate | Therapeutic Substance | Approved Drug | 24 |
| Lomefloxacin hydrochloride | Therapeutic Substance | Approved Drug | 24 |
| Thonzonium bromide | Therapeutic Substance | Approved Drug | 24 |
| Flumequine | Therapeutic Substance | Approved Drug | 23 |
| Streptozotocin | Therapeutic Substance | Approved Drug | 22 |
| Cefsulodin sodium salt | Therapeutic Substance | Approved Drug | 21 |
| Clarithromycin | Therapeutic Substance | Approved Drug; Antibiotics | 21 |
| Lead | Environmental Substance | Heavy Metals; Toxic Agents | 21 |
| Lymecycline | Therapeutic Substance | Approved Drug | 21 |
| Ofloxacin | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 21 |
| Oxiconazole Nitrate | Therapeutic Substance | Approved Drug | 21 |
| Trimethoprim | Therapeutic Substance | Approved Drug | 21 |
| Floxuridine | Therapeutic Substance | Approved Drug | 20 |
| Norfloxacin | Therapeutic Substance | Approved Drug | 20 |
| Bifonazole | Therapeutic Substance | Approved Drug | 19 |
| Colistin sulfate | Therapeutic Substance | Approved Drug | 19 |
| Doxorubicin hydrochloride | Therapeutic Substance | Approved Drug | 19 |
| Glyphosate-based herbicide | Environmental Substance | Pesticides | 19 |
| Hexestrol | Therapeutic Substance | Approved Drug | 19 |
| Pivampicillin | Therapeutic Substance | Approved Drug | 19 |
| Pyrimethamine | Therapeutic Substance | Approved Drug | 19 |
| Terfenadine | Therapeutic Substance | Approved Drug | 19 |
| Butoconazole nitrate | Therapeutic Substance | Approved Drug | 18 |
| Cefuroxime axetil | Therapeutic Substance | Approved Drug; Antibiotics | 18 |
| Chemotherapy | Therapeutic Substance | Drug Class | 18 |
| Dienestrol | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 18 |
| Laxatives | Therapeutic Substance | Drug Class | 18 |
| Cefaclor hydrate | Therapeutic Substance | Approved Drug | 17 |
| Felodipine | Therapeutic Substance | Approved Drug | 17 |
| Linum usitatissimum | Herbal Substance | Medicinal Herb | 17 |
| Mafenide hydrochloride | Therapeutic Substance | Approved Drug | 17 |
| Pefloxacine | Therapeutic Substance | Approved Drug | 17 |
| Zafirlukast | Therapeutic Substance | Approved Drug | 17 |
| Benzo[a]pyrene | Environmental Substance | Persistent Organic Pollutants | 16 |
| Cefoxitin | Therapeutic Substance | Approved Drug; Antibiotics | 16 |
| Etoposide | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 16 |
| Methotrexate | Therapeutic Substance | Approved Drug | 16 |
| Methylmercury | Environmental Substance | Heavy Metals; Toxic Agents | 16 |
| Propamocarb | Environmental Substance | Pesticides | 16 |
| Sertaconazole nitrate | Therapeutic Substance | Approved Drug | 16 |
| Statins | Therapeutic Substance | Drug Class | 16 |
| Tamoxifen citrate | Therapeutic Substance | Approved Drug | 16 |
| Antibiotics (previous month antibiotics) | Therapeutic Substance | Drug Class | 15 |
| Aspirin | Therapeutic Substance | Approved Drug | 15 |
| Clemizole hydrochloride | Therapeutic Substance | Approved Drug | 15 |
| Diethylstilbestrol | Therapeutic Substance | Approved Drug | 15 |
| Doxycycline | Therapeutic Substance | Approved Drug; Antibiotics | 15 |
| Gegen Qilian decoction | Herbal Substance | TCM Formula | 15 |
| Loratadine | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 15 |
| Pyrvinium pamoate | Therapeutic Substance | Approved Drug | 15 |
| Sulconazole Nitrate | Therapeutic Substance | Approved Drug | 15 |
| Telithromycin | Therapeutic Substance | Approved Drug; Antibiotics | 15 |
| Bepridil hydrochloride | Therapeutic Substance | Approved Drug | 14 |
| Cefepime | Therapeutic Substance | Approved Drug; Antibiotics | 14 |
| Gemcitabine | Therapeutic Substance | Approved Drug | 14 |
| Loracarbef | Therapeutic Substance | Approved Drug; Antibiotics | 14 |
| Meropenem | Therapeutic Substance | Approved Drug; Antibiotics | 14 |
| Norfloxacin | Therapeutic Substance | Approved Drug; Antibiotics | 14 |
| Ofloxacin | Therapeutic Substance | Approved Drug; Antibiotics | 14 |
| Rifaximin | Therapeutic Substance | Approved Drug; Antibiotics | 14 |
| Tazobactam | Therapeutic Substance | Approved Drug | 14 |
| Tiratricol, 3,3',5-triiodothyroacetic acid | Therapeutic Substance | Approved Drug | 14 |
| Amoxicillin/clavulanate | Therapeutic Substance | Approved Drug; Antibiotics | 13 |
| Cefaclor | Therapeutic Substance | Approved Drug; Antibiotics | 13 |
| Cefpodoxime Proxetil | Therapeutic Substance | Approved Drug; Antibiotics | 13 |
| Ceftriaxone | Therapeutic Substance | Approved Drug; Antibiotics | 13 |
| Clarithromycin plus metronidazole | Therapeutic Substance | Approved Drug; Antibiotics | 13 |
| Enilconazole | Environmental Substance | Pesticides | 13 |
| Enilconazole | Therapeutic Substance | Approved Drug (veterinary medicine) | 13 |
| Erythromycin | Therapeutic Substance | Approved Drug; Antibiotics | 13 |
| Mefloquine hydrochloride | Therapeutic Substance | Approved Drug | 13 |
| Penicillin | Therapeutic Substance | Approved Drug; Antibiotics | 13 |
| Thioridazine hydrochloride | Therapeutic Substance | Approved Drug | 13 |
| Ticarcillin/clavulanate | Therapeutic Substance | Approved Drug; Antibiotics | 13 |
| Troglitazone | Therapeutic Substance | Approved Drug | 13 |
| 2,2',4,4'-Tetrabromodiphenyl ether | Environmental Substance | Persistent Organic Pollutants | 12 |
| Amethopterin (R,S) | Therapeutic Substance | Approved Drug | 12 |
| Amoxicillin plus metronidazole | Therapeutic Substance | Approved Drug; Antibiotics | 12 |
| Azaguanine-8 | Therapeutic Substance | Approved Drug | 12 |
| Cefixime | Therapeutic Substance | Approved Drug; Antibiotics | 12 |
| Clinafloxacin | Therapeutic Substance | Approved Drug; Antibiotics | 12 |
| Clomiphene citrate (Z,E) | Therapeutic Substance | Approved Drug | 12 |
| Enoxacin | Therapeutic Substance | Approved Drug; Antibiotics | 12 |
| Glycyrrhiza glabra | Herbal Substance | Medicinal Herb | 12 |
| Lemofloxacin | Therapeutic Substance | Approved Drug; Antibiotics | 12 |
| Lenapenem | Therapeutic Substance | Approved Drug; Antibiotics | 12 |
| Levofloxacin | Therapeutic Substance | Approved Drug; Antibiotics | 12 |
| Mercuric chloride | Environmental Substance | Heavy Metals; Toxic Agents | 12 |
| Minocycline | Therapeutic Substance | Approved Drug; Antibiotics | 12 |
| Moxifloxacin | Therapeutic Substance | Approved Drug; Antibiotics | 12 |
| Nitrofurantoin | Therapeutic Substance | Approved Drug; Antibiotics | 12 |
| Perhexiline maleate | Therapeutic Substance | Approved Drug | 12 |
| Sparfloxacin | Therapeutic Substance | Approved Drug; Antibiotics | 12 |
| Zidovudine | Therapeutic Substance | Approved Drug | 12 |
| Amikacin hydrate | Therapeutic Substance | Approved Drug | 11 |
| Ampicillin | Therapeutic Substance | Approved Drug; Antibiotics | 11 |
| Anthralin | Therapeutic Substance | Approved Drug | 11 |
| Avermectin B1a | Therapeutic Substance | Approved Drug | 11 |
| Bacampicillin | Therapeutic Substance | Approved Drug; Antibiotics | 11 |
| Cichorium intybus | Herbal Substance | Medicinal Herb | 11 |
| Estradiol Valerate | Therapeutic Substance | Approved Drug | 11 |
| Ethopropazine hydrochloride | Therapeutic Substance | Approved Drug | 11 |
| Gemifloxacin | Therapeutic Substance | Approved Drug; Antibiotics | 11 |
| Mercury | Environmental Substance | Heavy Metals; Toxic Agents | 11 |
| Paracetamol | Therapeutic Substance | Approved Drug | 11 |
| PCB congeners (PCB153, PCB138, PCB180) | Environmental Substance | Persistent Organic Pollutants | 11 |
| Promazine hydrochloride | Therapeutic Substance | Approved Drug | 11 |
| Tobramycin | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 11 |
| Trifluridine | Therapeutic Substance | Approved Drug | 11 |
| Zingiber officinale | Herbal Substance | Medicinal Herb | 11 |
| 2,3,7,8-tetrachlorodibenzo-p-dioxin | Environmental Substance | Persistent Organic Pollutants | 10 |
| Amiodarone hydrochloride | Therapeutic Substance | Approved Drug | 10 |
| Aprepitant | Therapeutic Substance | Approved Drug | 10 |
| Astemizole | Therapeutic Substance | Approved Drug | 10 |
| Ceftibuten | Therapeutic Substance | Approved Drug; Antibiotics | 10 |
| Dicumarol | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 10 |
| Efavirenz | Therapeutic Substance | Approved Drug | 10 |
| Fosfomycin | Therapeutic Substance | Approved Drug; Antibiotics | 10 |
| Garenoxacin | Therapeutic Substance | Approved Drug; Antibiotics | 10 |
| Ketoconazole | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 10 |
| Methiothepin maleate | Therapeutic Substance | Approved Drug | 10 |
| Nopal | Herbal Substance | Medicinal Herb | 10 |
| Pinaverium bromide | Therapeutic Substance | Approved Drug | 10 |
| Pivmecillinam | Therapeutic Substance | Approved Drug; Antibiotics | 10 |
| Sitafloxacin | Therapeutic Substance | Approved Drug; Antibiotics | 10 |
| Tigecycline | Therapeutic Substance | Approved Drug; Antibiotics | 10 |
| Tolfenamic acid | Therapeutic Substance | Approved Drug | 10 |
| Vancomycin | Therapeutic Substance | Approved Drug; Antibiotics | 10 |
| 2,3,7,8-tetrachlorodibenzofuran | Environmental Substance | Persistent Organic Pollutants | 9 |
| Azlocillin | Therapeutic Substance | Approved Drug; Antibiotics | 9 |
| Ceftaroline | Therapeutic Substance | Approved Drug; Antibiotics | 9 |
| Diclazuril | Therapeutic Substance | Approved Drug (veterinary medicine) | 9 |
| Dirithromycin | Therapeutic Substance | Approved Drug; Antibiotics | 9 |
| Entacapone | Therapeutic Substance | Approved Drug | 9 |
| Fleroxacin | Therapeutic Substance | Approved Drug | 9 |
| Gatifloxacin | Therapeutic Substance | Approved Drug; Antibiotics | 9 |
| Metixene hydrochloride | Therapeutic Substance | Approved Drug | 9 |
| Metronidazole | Therapeutic Substance | Approved Drug; Antibiotics | 9 |
| Monoethylhexyl phthalate | Environmental Substance | Phthalates | 9 |
| Resveratrol | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 9 |
| Sertindole | Therapeutic Substance | Approved Drug | 9 |
| Stanozolol | Therapeutic Substance | Approved Drug | 9 |
| Toremifene | Therapeutic Substance | Approved Drug | 9 |
| Adalimumab | Therapeutic Substance | Approved Drug | 8 |
| Ceftaroline/avibactam | Therapeutic Substance | Approved Drug; Antibiotics | 8 |
| Ceftazidime/avibactam | Therapeutic Substance | Approved Drug; Antibiotics | 8 |
| Cephalosporanic acid, 7-amino | Therapeutic Substance | Approved Drug | 8 |
| Chlorprothixene hydrochloride | Therapeutic Substance | Approved Drug | 8 |
| Di(2-ethylhexyl) phthlate | Environmental Substance | Phthalates | 8 |
| Diazinon | Environmental Substance | Pesticides | 8 |
| Fendiline hydrochloride | Therapeutic Substance | Approved Drug | 8 |
| Gefitinib | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 8 |
| Infliximab | Therapeutic Substance | Approved Drug | 8 |
| Linezolid | Therapeutic Substance | Approved Drug; Antibiotics | 8 |
| Malathion | Environmental Substance | Pesticides | 8 |
| Meclozine dihydrochloride | Therapeutic Substance | Approved Drug | 8 |
| Montelukast | Therapeutic Substance | Approved Drug | 8 |
| Plantago asiatica L. | Herbal Substance | Medicinal Herb | 8 |
| Protriptyline hydrochloride | Therapeutic Substance | Approved Drug | 8 |
| Solithromycin | Therapeutic Substance | Approved Drug; Antibiotics | 8 |
| Suloctidil | Therapeutic Substance | Approved Drug | 8 |
| Telavancin | Therapeutic Substance | Approved Drug; Antibiotics | 8 |
| Tetrachlorodibenzo-p-dioxin | Environmental Substance | Persistent Organic Pollutants | 8 |
| Tylosin | Environmental Substance | Approved Drug; Antibiotics | 8 |
| Aldicarb | Environmental Substance | Pesticides | 7 |
| Alfacalcidol | Therapeutic Substance | Approved Drug | 7 |
| Apramycin | Therapeutic Substance; Herbal Substance | Approved Drug (veterinary medicine); Medicinal Herbal Compounds | 7 |
| Azathioprine | Therapeutic Substance | Approved Drug | 7 |
| Cefadroxil | Therapeutic Substance | Approved Drug; Antibiotics | 7 |
| Ceftobiprole | Therapeutic Substance | Approved Drug; Antibiotics | 7 |
| Chromium | Environmental Substance | Heavy Metals; Toxic Agents | 7 |
| Lansoprazole | Therapeutic Substance | Approved Drug | 7 |
| Loxapine succinate | Therapeutic Substance | Approved Drug | 7 |
| Magnoloside A | Herbal Substance | Medicinal Herbal Compounds | 7 |
| MCB3837 | Therapeutic Substance | Approved Drug; Antibiotics | 7 |
| Mixture | Therapeutic Substance; Environmental Substance | Approved Drug; Antibiotics | 7 |
| Moricizine hydrochloride | Therapeutic Substance | Approved Drug | 7 |
| Omeprazole | Therapeutic Substance | Approved Drug | 7 |
| p,p'-Dichlorodiphenyldichloroethylene | Environmental Substance | Pesticides | 7 |
| Pentachlorophenol | Environmental Substance | Pesticides | 7 |
| Pimozide | Therapeutic Substance | Approved Drug | 7 |
| Polysaccharide | Herbal Substance | Medicinal Herbal Compounds | 7 |
| Resveratrol | Therapeutic Substance | Approved Drug | 7 |
| Toltrazuril | Therapeutic Substance | Approved Drug (veterinary medicine) | 7 |
| Trimeprazine tartrate | Therapeutic Substance | Approved Drug | 7 |
| Ustekinumab | Therapeutic Substance | Approved Drug | 7 |
| Vancomycin | Environmental Substance | Approved Drug; Antibiotics | 7 |
| Zotepine | Therapeutic Substance | Approved Drug | 7 |
| Zuclopenthixol dihydrochloride | Therapeutic Substance | Approved Drug | 7 |
| Acarbose | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 6 |
| Amoxicillin | Environmental Substance | Approved Drug; Antibiotics | 6 |
| Amoxicillin | Therapeutic Substance; Environmental Substance | Approved Drug; Antibiotics | 6 |
| Anethole-trithione | Therapeutic Substance | Approved Drug | 6 |
| Aztreonam | Therapeutic Substance | Approved Drug | 6 |
| Butenafine Hydrochloride | Therapeutic Substance | Approved Drug | 6 |
| Cefotaxime | Therapeutic Substance | Approved Drug; Antibiotics | 6 |
| Cefotetan | Therapeutic Substance | Approved Drug; Antibiotics | 6 |
| Cefuroxime | Therapeutic Substance | Approved Drug; Antibiotics | 6 |
| Chlorotrianisene | Therapeutic Substance | Approved Drug | 6 |
| Chlorpromazine hydrochloride | Therapeutic Substance | Approved Drug | 6 |
| Chromium (VI) | Environmental Substance | Heavy Metals; Toxic Agents | 6 |
| Epoxiconazole | Environmental Substance | Pesticides | 6 |
| Ertapenem | Therapeutic Substance | Approved Drug; Antibiotics | 6 |
| Ethacrynic acid | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 6 |
| Ganoderma lucidum | Herbal Substance | Medicinal Herb | 6 |
| Hexetidine | Therapeutic Substance | Approved Drug | 6 |
| Hycanthone | Therapeutic Substance | Approved Drug | 6 |
| Lacidipine | Therapeutic Substance | Approved Drug | 6 |
| Latamoxef | Therapeutic Substance | Approved Drug; Antibiotics | 6 |
| Mezlocillin | Therapeutic Substance | Approved Drug; Antibiotics | 6 |
| Paromomycin | Therapeutic Substance | Approved Drug; Antibiotics | 6 |
| PCB mixture | Environmental Substance | Persistent Organic Pollutants | 6 |
| Pimethixene maleate | Therapeutic Substance | Approved Drug | 6 |
| Prochlorperazine dimaleate | Therapeutic Substance | Approved Drug | 6 |
| Promethazine hydrochloride | Therapeutic Substance | Approved Drug | 6 |
| Propidium iodide | Environmental Substance | Unclassified Environmental Substances | 6 |
| Rabeprazole Sodium salt | Therapeutic Substance | Approved Drug | 6 |
| Rosmarinus officinals | Herbal Substance | Medicinal Herb | 6 |
| Saccharin | Environmental Substance | Artificial Sweeteners | 6 |
| Splenda | Environmental Substance | Artificial Sweeteners | 6 |
| SSRI antidepressants | Therapeutic Substance | Drug Class | 6 |
| Streptomycin | Therapeutic Substance | Approved Drug; Antibiotics | 6 |
| Trifluoperazine dihydrochloride | Therapeutic Substance | Approved Drug | 6 |
| Trovafloxacin | Therapeutic Substance | Approved Drug; Antibiotics | 6 |
| Vaccinium myrtillus | Herbal Substance | Medicinal Herb | 6 |
| Vancomycin | Therapeutic Substance; Environmental Substance | Approved Drug; Antibiotics | 6 |
| 5-aminosalicylic acid | Therapeutic Substance | Approved Drug | 5 |
| Anti PD-1 therapy | Therapeutic Substance | Drug Class | 5 |
| Camellia sinensis | Herbal Substance | Medicinal Herb | 5 |
| Carbendazim | Environmental Substance | Pesticides | 5 |
| Cefuroxime axetil than vancomycIn | Therapeutic Substance | Approved Drug; Antibiotics | 5 |
| Cilnidipine | Therapeutic Substance | Approved Drug | 5 |
| Cyclosporin A | Therapeutic Substance | Approved Drug | 5 |
| Dalbavancin | Therapeutic Substance | Approved Drug; Antibiotics | 5 |
| Dichlorodiphenyl-dichloroethylene | Environmental Substance | Pesticides | 5 |
| Ethaverine hydrochloride | Therapeutic Substance | Approved Drug | 5 |
| Fleroxacin | Therapeutic Substance | Approved Drug; Antibiotics | 5 |
| Flucloxacillin | Therapeutic Substance | Approved Drug; Antibiotics | 5 |
| Fluphenazine dihydrochloride | Therapeutic Substance | Approved Drug | 5 |
| Fox River mixture (PCBs mixture) | Environmental Substance | Persistent Organic Pollutants | 5 |
| Halofantrine hydrochloride | Therapeutic Substance | Approved Drug | 5 |
| Hexachlorocyclo hexane | Environmental Substance | Pesticides | 5 |
| Idoxuridine | Therapeutic Substance | Approved Drug | 5 |
| Ivermectin | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 5 |
| Meclofenamic acid sodium salt monohydrate | Therapeutic Substance | Approved Drug | 5 |
| Mixture | Environmental Substance | Approved Drug; Antibiotics | 5 |
| Nickel | Environmental Substance | Heavy Metals; Toxic Agents | 5 |
| Opiates (opioid) | Therapeutic Substance | Drug Class | 5 |
| Parbendazole | Therapeutic Substance | Approved Drug (veterinary medicine) | 5 |
| Permethrin | Environmental Substance | Pesticides | 5 |
| Piperacillin | Therapeutic Substance | Approved Drug; Antibiotics | 5 |
| Prenylamine lactate | Therapeutic Substance | Approved Drug | 5 |
| Quinacrine dihydrochloride dihydrate | Therapeutic Substance | Approved Drug | 5 |
| Rulfoxacin | Therapeutic Substance | Approved Drug; Antibiotics | 5 |
| Spectinomycin dihydrochloride | Therapeutic Substance | Approved Drug | 5 |
| Ticarcillin | Therapeutic Substance | Approved Drug; Antibiotics | 5 |
| Tolnaftate | Therapeutic Substance | Approved Drug | 5 |
| Triclosan | Environmental Substance | Unclassified Environmental Substances | 5 |
| Tricyclic antidepressants | Therapeutic Substance | Drug Class | 5 |
| Tylosin | Therapeutic Substance; Environmental Substance | Approved Drug; Antibiotics | 5 |
| Alpha blockers | Therapeutic Substance | Drug Class | 4 |
| Arsenic and zinc | Environmental Substance | Heavy Metals; Toxic Agents | 4 |
| Azelastine HCl | Therapeutic Substance | Approved Drug | 4 |
| Cefprozil | Therapeutic Substance | Approved Drug; Antibiotics | 4 |
| Cefuroxime axetil followed vancomycin | Therapeutic Substance | Approved Drug; Antibiotics | 4 |
| Cephazolin | Therapeutic Substance | Approved Drug; Antibiotics | 4 |
| Cinoxacin | Therapeutic Substance | Approved Drug | 4 |
| Clofilium tosylate | Therapeutic Substance | Approved Drug | 4 |
| Crude extracts of metabolites from Microcystis aeruginosa | Environmental Substance | Biological Contaminants | 4 |
| Curcumin | Therapeutic Substance; Herbal Substance | Investigational Drug; Medicinal Herbal Compounds | 4 |
| Cyclobenzaprine hydrochloride | Therapeutic Substance | Approved Drug | 4 |
| Diethyl phosphate (metabolite of CPF+ others)(I) | Environmental Substance | Pesticides | 4 |
| Dihydrostreptomycin sulfate | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 4 |
| DMP, DEP, and DBP combined | Environmental Substance | Phthalates | 4 |
| Etomidate | Therapeutic Substance | Approved Drug | 4 |
| Fipronil | Environmental Substance | Pesticides | 4 |
| Flufenamic acid | Therapeutic Substance | Approved Drug | 4 |
| Haloprogin | Therapeutic Substance | Approved Drug | 4 |
| Lidoflazine | Therapeutic Substance | Approved Drug | 4 |
| Mercaptopurine | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 4 |
| Nalidixic acid sodium salt | Therapeutic Substance | Approved Drug | 4 |
| Oligofructose | Herbal Substance | Medicinal Herbal Compounds | 4 |
| Oxolinic acid | Therapeutic Substance | Approved Drug | 4 |
| Perphenazine | Therapeutic Substance | Approved Drug | 4 |
| PFAS: F-53B | Environmental Substance | Persistent Organic Pollutants | 4 |
| Proadifen hydrochloride | Environmental Substance | Unclassified Environmental Substances | 4 |
| Quinupristin/dalfopristin | Therapeutic Substance | Approved Drug; Antibiotics | 4 |
| Roxithromycin | Therapeutic Substance | Approved Drug; Antibiotics | 4 |
| Saquinavir mesylate | Therapeutic Substance | Approved Drug | 4 |
| Teicoplanin | Therapeutic Substance | Approved Drug; Antibiotics | 4 |
| Telmisartan | Therapeutic Substance | Approved Drug | 4 |
| Tenatoprazole | Therapeutic Substance | Approved Drug | 4 |
| Thiamethoxam | Environmental Substance | Pesticides | 4 |
| Thiethylperazine dimalate | Therapeutic Substance | Approved Drug | 4 |
| Vardenafil | Therapeutic Substance | Approved Drug | 4 |
| Vecuronium bromide | Therapeutic Substance | Approved Drug | 4 |
| Zn(ii)-curcumin | Environmental Substance | Nutrient Supplement | 4 |
| Acesulfame potassium | Environmental Substance | Artificial Sweeteners | 3 |
| Amodiaquin dihydrochloride dihydrate | Therapeutic Substance | Approved Drug | 3 |
| aracytine | Therapeutic Substance | Approved Drug | 3 |
| Aripiprazole | Therapeutic Substance | Approved Drug | 3 |
| Asenapine maleate | Therapeutic Substance | Approved Drug | 3 |
| Aspartame | Environmental Substance | Artificial Sweeteners | 3 |
| Atrazine | Environmental Substance | Pesticides | 3 |
| Azithromycin | Therapeutic Substance | Approved Drug; Antibiotics | 3 |
| Beta blockers | Therapeutic Substance | Drug Class | 3 |
| bisphenol A; ethinyl estradiol | Environmental Substance | Industrial Compounds; Bisphenols | 3 |
| carmustine | Therapeutic Substance | Approved Drug | 3 |
| Cinnarizine | Therapeutic Substance | Approved Drug | 3 |
| Cladribine | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 3 |
| DEP; methylparaben; triclosan | Environmental Substance | Phthalates | 3 |
| Epirizole | Therapeutic Substance | Approved Drug | 3 |
| Etoposide | Therapeutic Substance | Approved Drug | 3 |
| Fluorouracil | Therapeutic Substance | Approved Drug | 3 |
| GBR 12909 dihydrochloride | Therapeutic Substance | Approved Drug | 3 |
| Gentamicine sulfate | Therapeutic Substance | Approved Drug | 3 |
| Hexachlorocyclohexane | Environmental Substance | Pesticides | 3 |
| Idebenone | Therapeutic Substance | Approved Drug | 3 |
| Imidacloprid | Environmental Substance | Pesticides | 3 |
| Indatraline hydrochloride | Environmental Substance | Unclassified Environmental Substances | 3 |
| Iohexol | Therapeutic Substance | Approved Drug | 3 |
| Irinotecan | Therapeutic Substance | Approved Drug | 3 |
| Isosorbide dinitrate | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 3 |
| Melphalan | Therapeutic Substance | Approved Drug | 3 |
| Mesoridazine besylate | Therapeutic Substance | Approved Drug | 3 |
| Mifepristone | Therapeutic Substance | Approved Drug | 3 |
| Nalidixic acid | Therapeutic Substance | Approved Drug; Antibiotics | 3 |
| Omega-3 PUFA supplementation | Environmental Substance | Dietary Compounds | 3 |
| Other bisphenols | Environmental Substance | Industrial Compounds; Bisphenols | 3 |
| Penicillin | Therapeutic Substance; Environmental Substance | Approved Drug; Antibiotics | 3 |
| Perfluorobutanesulfonic acid | Environmental Substance | Persistent Organic Pollutants | 3 |
| Pipemidic acid | Therapeutic Substance | Approved Drug | 3 |
| Pomegranate extract | Herbal Substance; Dietary Substance | Herbal Substance; Dietary Substance | 3 |
| Ribavirin | Therapeutic Substance | Approved Drug | 3 |
| Ritipenem acoxil | Therapeutic Substance | Approved Drug; Antibiotics | 3 |
| Saccharin | Therapeutic Substance; Dietary Substance; Herbal Substance | Investigational Drug; Dietary Compounds; Artificial Sweetener; Medicinal Herbal Compounds | 3 |
| Sertraline | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 3 |
| Silybum marianum | Herbal Substance | Medicinal Herb | 3 |
| Simvastatin | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 3 |
| Sodium butyrate | Environmental Substance | Microbiota metabolite | 3 |
| Sucralose | Environmental Substance | Artificial Sweeteners | 3 |
| Sulbactam | Therapeutic Substance | Approved Drug | 3 |
| Thioguanosine | Therapeutic Substance | Approved Drug | 3 |
| Thyroxine (L) | Therapeutic Substance | Approved Drug | 3 |
| Trimethoprim | Therapeutic Substance | Approved Drug; Antibiotics | 3 |
| Acacia catechu | Herbal Substance | Medicinal Herb | 2 |
| ACE inhibitors | Therapeutic Substance | Drug Class | 2 |
| Acenocoumarol | Therapeutic Substance | Approved Drug | 2 |
| Acetopromazine maleate salt | Therapeutic Substance | Approved Drug | 2 |
| Albendazole | Therapeutic Substance | Approved Drug | 2 |
| Aloe vera | Herbal Substance | Medicinal Herb | 2 |
| Aloin | Herbal Substance | Medicinal Herbal Compounds | 2 |
| AMC formula | Herbal Substance | TCM Formula | 2 |
| Amlodipine | Therapeutic Substance | Approved Drug | 2 |
| Amoxapine | Therapeutic Substance | Approved Drug | 2 |
| Atovaquone | Therapeutic Substance | Approved Drug | 2 |
| Bawei Xileisan | Herbal Substance | TCM Formula | 2 |
| Caffeic acid | Herbal Substance | Medicinal Herbal Compounds | 2 |
| Carbamate aldicarb | Environmental Substance | Pesticides | 2 |
| Carbenoxolone disodium salt | Therapeutic Substance | Approved Drug | 2 |
| carboxymethylcellulose or polysorbate-80 | Environmental Substance | Food Additives | 2 |
| Cefadroxil | Therapeutic Substance | Approved Drug | 2 |
| Cephaloridine | Therapeutic Substance | Approved Drug; Antibiotics | 2 |
| Cinnamon essential oil | Environmental Substance | Unclassified Environmental Substances | 2 |
| Ciprofloxacin plus clindamycin | Therapeutic Substance | Approved Drug; Antibiotics | 2 |
| Clavulanate potassium salt | Therapeutic Substance | Approved Drug | 2 |
| Curcuma longa | Herbal Substance | Medicinal Herb | 2 |
| Deoxynivalenol | Environmental Substance | Biological Contaminants | 2 |
| Emulsi?ers (P80 and CMC) | Environmental Substance | Unclassified Environmental Substances | 2 |
| Erlotinib | Therapeutic Substance | Approved Drug | 2 |
| Etanercept | Therapeutic Substance | Approved Drug | 2 |
| Etofenamate | Therapeutic Substance | Approved Drug | 2 |
| Fenbendazole | Therapeutic Substance | Approved Drug | 2 |
| Flunixin meglumine | Therapeutic Substance | Approved Drug (veterinary medicine) | 2 |
| Fluspirilen | Therapeutic Substance | Approved Drug | 2 |
| Folic acid | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 2 |
| Gallic acid | Herbal Substance | Medicinal Herbal Compounds | 2 |
| Glycyrrhiza uralensis | Herbal Substance | Medicinal Herb | 2 |
| Haloperidol | Therapeutic Substance | Approved Drug | 2 |
| Hydrocortisone base | Therapeutic Substance | Approved Drug | 2 |
| lactam | Environmental Substance | Approved Drug; Antibiotics | 2 |
| Leflunomide | Therapeutic Substance | Approved Drug | 2 |
| Loperamide hydrochloride | Therapeutic Substance | Approved Drug | 2 |
| Lynestrenol | Therapeutic Substance | Approved Drug | 2 |
| Manganese | Environmental Substance | Heavy Metals; Toxic Agents | 2 |
| Mebhydroline 1,5-naphtalenedisulfonate | Therapeutic Substance | Approved Drug | 2 |
| Metergoline | Therapeutic Substance | Approved Drug | 2 |
| Mitotane | Therapeutic Substance | Approved Drug | 2 |
| Nicardipine hydrochloride | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 2 |
| Nilutamide | Therapeutic Substance | Approved Drug | 2 |
| Norcyclobenzaprine | Therapeutic Substance | Approved Drug | 2 |
| PCB congeners | Environmental Substance | Persistent Organic Pollutants | 2 |
| PCB-126 | Environmental Substance | Persistent Organic Pollutants | 2 |
| Pefloxacin | Therapeutic Substance | Approved Drug; Antibiotics | 2 |
| Pemirolast potassium | Therapeutic Substance | Approved Drug | 2 |
| Pioglitazone | Therapeutic Substance | Approved Drug | 2 |
| Pivmecillinam hydrochloride | Therapeutic Substance | Approved Drug | 2 |
| Polymyxin E | Therapeutic Substance | Approved Drug; Antibiotics | 2 |
| Pridinol methanesulfonate salt | Therapeutic Substance | Approved Drug | 2 |
| Quercetin | Herbal Substance | Medicinal Herbal Compounds | 2 |
| Racepinephrine HCl | Therapeutic Substance | Approved Drug | 2 |
| Red Ginseng | Herbal Substance | Medicinal Herb | 2 |
| Riluzole hydrochloride | Therapeutic Substance | Approved Drug | 2 |
| saccharin; sucralose; aspartame | Environmental Substance | Noncaloric Artificial Sweeteners (NAS) | 2 |
| Salvia officinalis | Herbal Substance | Medicinal Herb | 2 |
| Semen Coicis | Herbal Substance | Medicinal Herb | 2 |
| Sisomicin sulfate | Therapeutic Substance | Approved Drug | 2 |
| Streptomycin | Environmental Substance | Approved Drug; Antibiotics | 2 |
| Tau-?uvalinate | Environmental Substance | Pesticides | 2 |
| Traffic-related air | Environmental Substance | Environmental Chemicals | 2 |
| Trichlorfon | Environmental Substance | Pesticides | 2 |
| Triflupromazine hydrochloride | Therapeutic Substance | Approved Drug | 2 |
| Trimethoprim/sulfamethoxazole | Therapeutic Substance | Approved Drug; Antibiotics | 2 |
| Urolithin-A | Herbal Substance | Medicinal Herbal Compounds | 2 |
| Vedolizumab | Therapeutic Substance | Approved Drug | 2 |
| Xiao-Qing-Long Tang | Herbal Substance | TCM Formula | 2 |
| Abacavir Sulfate | Therapeutic Substance | Approved Drug | 1 |
| Aflatoxin B1 | Environmental Substance | Biological Contaminants | 1 |
| Alverine citrate salt | Therapeutic Substance | Approved Drug | 1 |
| Amiprilose hydrochloride | Environmental Substance | Unclassified Environmental Substances | 1 |
| Amphotericin B | Therapeutic Substance | Approved Drug | 1 |
| Anidulafungin (LY303366) | Therapeutic Substance | Approved Drug | 1 |
| Antihistamines (H1 inhibitor) | Therapeutic Substance | Drug Class | 1 |
| Antihistamines (H2 inhibitor) | Therapeutic Substance | Drug Class | 1 |
| Antihistamines (H3 inhibitor) | Therapeutic Substance | Drug Class | 1 |
| Antrodia cinnamomea | Herbal Substance | Medicinal Herb | 1 |
| Artemisinin | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 1 |
| Aspartame | Therapeutic Substance; Dietary Substance; Herbal Substance | Dietary Compounds; Artificial Sweetener; Medicinal Herbal Compounds | 1 |
| Atrazine; estradiol; PCB126; PCB153 | Environmental Substance | Persistent Organic Pollutants | 1 |
| Azacytidine-5 | Therapeutic Substance | Approved Drug | 1 |
| Azoxystrobin | Environmental Substance | Pesticides | 1 |
| Benfluorex hydrochloride | Therapeutic Substance | Approved Drug | 1 |
| Benzydamine hydrochloride | Therapeutic Substance | Approved Drug | 1 |
| Berry fruits(cranberries; raspberries) | Environmental Substance | Foods | 1 |
| Betaxolol hydrochloride | Therapeutic Substance | Approved Drug | 1 |
| Bosentan | Therapeutic Substance | Approved Drug | 1 |
| Bromperidol | Therapeutic Substance | Approved Drug | 1 |
| Broxyquinoline | Therapeutic Substance | n.a. | 1 |
| Bufexamac | Therapeutic Substance | Approved Drug | 1 |
| Butamben | Therapeutic Substance | Approved Drug | 1 |
| Butoconazole | Therapeutic Substance | Approved Drug | 1 |
| Butylparaben | Environmental Substance | Unclassified Environmental Substances | 1 |
| Calcium | Therapeutic Substance | Approved Drug | 1 |
| Carvedilol | Therapeutic Substance | Approved Drug | 1 |
| Caspofungin Acetate | Therapeutic substance | n.a. | 1 |
| Cefetamet-pivoxil | Therapeutic Substance | Approved Drug; Antibiotics | 1 |
| Cefpirome | Therapeutic Substance | Approved Drug; Antibiotics | 1 |
| Cetrimonium Bromide (CTAB) | Therapeutic Substance | Phase 2 | 1 |
| Cetylpyridinium Chloride | Therapeutic substance | n.a. | 1 |
| Chlorcyclizine hydrochloride | Therapeutic Substance | Approved Drug | 1 |
| Chlorothalonil | Environmental Substance | Pesticides | 1 |
| Chlorpheniramine maleate | Therapeutic Substance | Approved Drug | 1 |
| Chlorquinaldol | Therapeutic Substance | n.a. | 1 |
| Clomipramine hydrochloride | Therapeutic Substance | Approved Drug | 1 |
| Cloxiquine | Therapeutic substance | n.a. | 1 |
| Cyclamate | Environmental Substance | Artificial Sweeteners | 1 |
| Cyclopenthiazide | Therapeutic Substance | Approved Drug | 1 |
| Cyproheptadine hydrochloride | Therapeutic Substance | Approved Drug | 1 |
| Dacarbazine | Therapeutic Substance | Approved Drug | 1 |
| Dantrolene sodium salt | Therapeutic Substance | Approved Drug | 1 |
| Darifenacin hydrobromide | Therapeutic Substance | Approved Drug | 1 |
| Demecarium bromide | Therapeutic Substance | Approved Drug | 1 |
| Deptropine citrate | Therapeutic Substance | Approved Drug | 1 |
| Dicyclomine hydrochloride | Therapeutic Substance | Approved Drug | 1 |
| Digoxin | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 1 |
| Diloxanide furoate | Therapeutic Substance | Approved Drug | 1 |
| Dimethisoquin hydrochloride | Therapeutic Substance | Approved Drug | 1 |
| Disulfiram | Therapeutic Substance | Approved Drug | 1 |
| Doxazosin mesylate | Therapeutic Substance | Approved Drug | 1 |
| Eburnamonine (-) | Therapeutic Substance | Approved Drug | 1 |
| Estropipate | Therapeutic Substance | Approved Drug | 1 |
| Etretinate | Therapeutic Substance | Approved Drug | 1 |
| Evans Blue | Therapeutic Substance | Approved Drug | 1 |
| Everolimus (RAD001) | Therapeutic Substance | Approved Drug | 1 |
| Fadrozole hydrochloride | Therapeutic Substance | Approved Drug | 1 |
| Famotidine | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 1 |
| Famprofazone | Therapeutic Substance | Approved Drug | 1 |
| Fenbufen | Therapeutic Substance | Approved Drug | 1 |
| Fentiazac | Therapeutic Substance | Approved Drug | 1 |
| Fenticonazole Nitrate | Therapeutic substance | n.a. | 1 |
| Fexofenadine HCl | Therapeutic Substance | Approved Drug | 1 |
| Flucytosine | Therapeutic Substance | antifungals | 1 |
| Flucytosine | Therapeutic Substance | Approved Drug | 1 |
| Fludarabine | Therapeutic Substance | Approved Drug | 1 |
| Flunarizine dihydrochloride | Therapeutic Substance | Approved Drug | 1 |
| Fluorometholone | Therapeutic Substance | Approved Drug | 1 |
| Fluorouracil (5-Fluoracil, 5-FU) | Therapeutic Substance | Approved Drug | 1 |
| Glafenine hydrochloride | Therapeutic Substance | Approved Drug | 1 |
| Gliquidone | Therapeutic Substance | Approved Drug | 1 |
| Guanadrel sulfate | Therapeutic Substance | Approved Drug | 1 |
| Hexachlorocyclohexane | Environmental Substance | Persistent Organic Pollutants | 1 |
| Ibutilide fumarate | Therapeutic Substance | Approved Drug | 1 |
| Imiquimod | Therapeutic Substance | Approved Drug | 1 |
| Iocetamic acid | Therapeutic Substance | Approved Drug | 1 |
| Iopanoic acid | Therapeutic Substance | Approved Drug | 1 |
| Isavuconazole | Therapeutic Substance | Phase 3 | 1 |
| Itraconazole | Therapeutic Substance | Approved Drug | 1 |
| lactam | Therapeutic Substance; Environmental Substance | Approved Drug; Antibiotics | 1 |
| Metformin | Environmental Substance | Approved Drug | 1 |
| Metformin | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 1 |
| Methantheline bromide | Therapeutic Substance | Approved Drug | 1 |
| Methiazole | Therapeutic Substance | Approved Drug | 1 |
| Methotrimeprazine maleat salt | Therapeutic Substance | Approved Drug | 1 |
| Metronidazole | Environmental Substance | Approved Drug; Antibiotics | 1 |
| Metronidazole | Therapeutic Substance; Environmental Substance | Approved Drug; Antibiotics | 1 |
| Micafungin Sodium | Therapeutic substance | n.a. | 1 |
| Miconazole Nitrate | Therapeutic substance | n.a. | 1 |
| Miltefosine | Therapeutic Substance | Approved Drug | 1 |
| Mitoxantrone 2HCl | Therapeutic substance | n.a. | 1 |
| Mometasone furoate | Therapeutic Substance | Approved Drug | 1 |
| N6-methyladenosine | Environmental Substance | Unclassified Environmental Substances | 1 |
| Naftopidil dihydrochloride | Therapeutic Substance | Approved Drug | 1 |
| Natamycin | Therapeutic Substance | Approved Drug | 1 |
| Nefazodone HCl | Therapeutic Substance | Approved Drug | 1 |
| Neotame | Environmental Substance | Artificial Sweeteners | 1 |
| Nicorandil | Therapeutic Substance | Approved Drug | 1 |
| Nicotine | Environmental Substance | Unclassified Environmental Substances | 1 |
| Nimesulide | Therapeutic Substance | Approved Drug | 1 |
| Nimodipine | Therapeutic Substance | Approved Drug | 1 |
| Nitroxoline | Therapeutic Substance | Patented | 1 |
| Norgestimate | Therapeutic Substance | Approved Drug | 1 |
| NSAIDs and sulfasalazine therapy | Therapeutic Substance | Drug Class | 1 |
| Nystatin (Fungicidin) | Therapeutic substance | n.a. | 1 |
| Ochratoxin A | Environmental Substance | Biological Contaminants | 1 |
| Octenidine Dihydrochloride | Therapeutic substance | n.a. | 1 |
| Oil tea | Herbal Substance | Medicinal Herb | 1 |
| Olanexidine Hydrochloride semihydrate | Therapeutic Substance | Registered Drug | 1 |
| Oxaprozin | Therapeutic Substance | Approved Drug | 1 |
| Oxibendazol | Therapeutic Substance | Approved Drug (veterinary medicine) | 1 |
| Paclitaxel | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 1 |
| Penicillin G; erythromycin, or both | Therapeutic Substance; Environmental Substance | Approved Drug; Antibiotics | 1 |
| Perifosine (KRX-0401) | Therapeutic Substance | Phase 1 | 1 |
| Phenformin | Therapeutic Substance | Approved Drug | 1 |
| Phenindione | Therapeutic Substance | Approved Drug | 1 |
| Piroctone Olamine | Therapeutic substance | n.a. | 1 |
| Pizotifen malate | Therapeutic Substance | Approved Drug | 1 |
| Polycyclic aromatic hydrocarbon | Environmental Substance | Persistent Organic Pollutants | 1 |
| Posaconazole | Therapeutic substance | Drug | 1 |
| Potentilla discolor Bunge | Herbal Substance | Medicinal Herb | 1 |
| Pranlukast | Therapeutic Substance | Approved Drug | 1 |
| Prilocaine hydrochloride | Therapeutic Substance | Approved Drug | 1 |
| Quetiapine hemifumarate | Therapeutic Substance | Approved Drug | 1 |
| Qushi Huayu Fang | Herbal Substance | TCM Formula | 1 |
| R(-) Apomorphine hydrochloride hemihydrate | Therapeutic Substance | Approved Drug | 1 |
| Raloxifene hydrochloride | Therapeutic Substance | Approved Drug | 1 |
| Rapamycin (Sirolimus) | Therapeutic Substance | Approved Drug | 1 |
| Reserpine | Therapeutic Substance; Herbal Substance | Approved Drug; Medicinal Herbal Compounds | 1 |
| Ribostamycin sulfate salt | Therapeutic Substance | Approved Drug | 1 |
| Ridaforolimus (Deforolimus, MK-8669) | Therapeutic substance | n.a. | 1 |
| Rifaximin | Environmental Substance | Approved Drug; Antibiotics | 1 |
| Rifaximin | Therapeutic Substance; Environmental Substance | Approved Drug; Antibiotics | 1 |
| Salmeterol | Therapeutic Substance | Approved Drug | 1 |
| Silver nanoparticles | Environmental Substance | Nanoparticles (NPs) | 1 |
| Spiperone | Therapeutic Substance | Approved Drug | 1 |
| Streptomycin | Therapeutic Substance; Environmental Substance | Approved Drug; Antibiotics | 1 |
| Sulfamonomethoxine | Therapeutic Substance | Approved Drug (veterinary medicine) | 1 |
| Sulfasalazine | Therapeutic Substance | Approved Drug | 1 |
| Sulphalene | Therapeutic Substance | Approved Drug; Antibiotics | 1 |
| Sulphasomidine | Therapeutic Substance | Approved Drug; Antibiotics | 1 |
| Sumatriptan succinate | Therapeutic Substance | Approved Drug | 1 |
| Tavaborole (AN-2690) | Therapeutic Substance | n.a. | 1 |
| Temozolomide | Therapeutic Substance | Approved Drug | 1 |
| Temsirolimus (CCI-779, NSC 683864) | Therapeutic Substance | Approved Drug | 1 |
| Terminalia arjuna | Herbal Substance | Medicinal Herb | 1 |
| Testosterone propionate | Therapeutic Substance | Approved Drug | 1 |
| Thiopurines | Therapeutic Substance | Approved Drug | 1 |
| Tracazolate hydrochloride | Environmental Substance | Unclassified Environmental Substances | 1 |
| Trazodone hydrochloride | Therapeutic Substance | Approved Drug | 1 |
| Tribenoside | Therapeutic Substance | Approved Drug | 1 |
| Vitamin D | Therapeutic Substance | Approved Drug | 1 |
| Voriconazole | Therapeutic Substance | Approved Drug | 1 |
| Zileuton | Therapeutic Substance | Approved Drug | 1 |
| Zinc Pyrithione | Therapeutic Substance | Investigational Drug | 1 |
| Ziprasidone Hydrochloride | Therapeutic Substance | Approved Drug | 1 |
| Zotarolimus(ABT-578) | Therapeutic substance | n.a. | 1 |