| DBID |
drug_substrate |
drug_metabolite |
Gene |
Reaction description |
Reaction formula |
SUBSYSTEM |
class_type |
class_level_1 |
class_level_2 |
class_level_3 |
References |
| DB01050 |
1-Hydroxy S-Ibuprofen-Glucuronide |
1-Hydroxy S-Ibuprofen |
UidAc |
1-hydroxy S-ibuprofen beta-glucuronidase |
1-hydroxy S-ibuprofen-glucuronide[c] + h2o[c] -> 1-hydroxy S-ibuprofen[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01050 |
1-Hydroxy S-Ibuprofen-Glucuronide |
1-Hydroxy S-Ibuprofen |
UidAe |
1-hydroxy S-ibuprofen beta-glucuronidase extracellular |
1-hydroxy S-ibuprofen-glucuronide[e] + h2o[e] -> 1-hydroxy S-ibuprofen[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01050 |
1-Hydroxy S-Ibuprofen-Glucuronide |
1-Hydroxy S-Ibuprofen |
UidAe |
1-hydroxy S-ibuprofen beta-glucuronidase extracellular, periplasmatic |
1-hydroxy S-ibuprofen-glucuronide[p] + h2o[p] -> 1-hydroxy S-ibuprofen[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01050 |
1-Hydroxy S-Ibuprofen |
1-Hydroxy S-Ibuprofen |
UidABC |
Predicted glucuronide ABC transporter 1-hydroxy S-ibuprofen |
atp[c] + 1-hydroxy S-ibuprofen[e] + h2o[c] -> adp[c] + 1-hydroxy S-ibuprofen[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
1-Hydroxy S-Ibuprofen |
1-Hydroxy S-Ibuprofen |
UidB |
Transport of D-Glucuronate 1-hydroxy S-ibuprofen |
1-hydroxy S-ibuprofen[e] -> 1-hydroxy S-ibuprofen[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
1-Hydroxy S-Ibuprofen |
1-Hydroxy S-Ibuprofen |
UidB |
Glucuronate transport in via proton symport 1-hydroxy S-ibuprofen |
1-hydroxy S-ibuprofen[e] + h[e] -> 1-hydroxy S-ibuprofen[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
1-Hydroxy S-Ibuprofen |
1-Hydroxy S-Ibuprofen |
n.a. |
beta-glucuronidase reaction product export,1-hydroxy S-ibuprofen |
1-hydroxy S-ibuprofen[c] -> 1-hydroxy S-ibuprofen[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
1-Hydroxy S-Ibuprofen |
1-Hydroxy S-Ibuprofen |
n.a. |
beta-glucuronidase reaction product export,1-hydroxy S-ibuprofen, periplasmatic |
1-hydroxy S-ibuprofen[c] -> 1-hydroxy S-ibuprofen[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
1-Hydroxy S-Ibuprofen |
1-Hydroxy S-Ibuprofen |
n.a. |
1-hydroxy S-ibuprofen diffusion extracellular to periplasm |
1-hydroxy S-ibuprofen[e] <=> 1-hydroxy S-ibuprofen[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
1-Hydroxy S-Ibuprofen-Glucuronide |
1-Hydroxy S-Ibuprofen-Glucuronide |
UidABC |
Predicted glucuronide ABC transporter (in),1-hydroxy S-ibuprofen-glucuronide |
atp[c] + 1-hydroxy S-ibuprofen-glucuronide[e] + h2o[c] -> adp[c] + 1-hydroxy S-ibuprofen-glucuronide[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
1-Hydroxy S-Ibuprofen-Glucuronide |
1-Hydroxy S-Ibuprofen-Glucuronide |
UidB |
Transport of D-Glucuronate (in),1-hydroxy S-ibuprofen-glucuronide |
1-hydroxy S-ibuprofen-glucuronide[e] -> 1-hydroxy S-ibuprofen-glucuronide[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
1-Hydroxy S-Ibuprofen-Glucuronide |
1-Hydroxy S-Ibuprofen-Glucuronide |
UidB |
Glucuronate transport in via proton symport (in),1-hydroxy S-ibuprofen-glucuronide |
1-hydroxy S-ibuprofen-glucuronide[e] + h[e] -> 1-hydroxy S-ibuprofen-glucuronide[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
1-Hydroxy S-Ibuprofen-Glucuronide |
1-Hydroxy S-Ibuprofen-Glucuronide |
UidB |
Glucuronate transport in via proton symport (in),1-hydroxy S-ibuprofen-glucuronide, periplasmatic |
1-hydroxy S-ibuprofen-glucuronide[p] + h[p] -> 1-hydroxy S-ibuprofen-glucuronide[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
1-Hydroxy S-Ibuprofen-Glucuronide |
1-Hydroxy S-Ibuprofen-Glucuronide |
n.a. |
beta-glucuronidase reaction product export 1-hydroxy S-ibuprofen-glucuronide |
1-hydroxy S-ibuprofen-glucuronide[c] -> 1-hydroxy S-ibuprofen-glucuronide[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
1-Hydroxy S-Ibuprofen-Glucuronide |
1-Hydroxy S-Ibuprofen-Glucuronide |
n.a. |
1-hydroxy S-ibuprofen-glucuronide diffusion extracellular to periplasm |
1-hydroxy S-ibuprofen-glucuronide[e] <=> 1-hydroxy S-ibuprofen-glucuronide[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
1'-Oh-Midazolam-Glucuronide |
1'-Oh-Midazolam |
UidAc |
1-OH-midazolam-glucuronide beta-glucuronidase |
1'-OH-midazolam-glucuronide[c] + h2o[c] -> 1'-OH-midazolam[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00683 |
1'-Oh-Midazolam-Glucuronide |
1'-Oh-Midazolam |
UidAe |
1-OH-midazolam-glucuronide beta-glucuronidase extracellular |
1'-OH-midazolam-glucuronide[e] + h2o[e] -> 1'-OH-midazolam[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00683 |
1'-Oh-Midazolam-Glucuronide |
1'-Oh-Midazolam |
UidAe |
1-OH-midazolam-glucuronide beta-glucuronidase extracellular, periplasmatic |
1'-OH-midazolam-glucuronide[p] + h2o[p] -> 1'-OH-midazolam[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00683 |
1'-Oh-Midazolam-Glucuronide |
1'-Oh-Midazolam-Glucuronide |
UidABC |
Predicted glucuronide ABC transporter 1-OH-midazolam-glucuronide |
atp[c] + 1'-OH-midazolam-glucuronide[e] + h2o[c] -> adp[c] + 1'-OH-midazolam-glucuronide[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
1'-Oh-Midazolam-Glucuronide |
1'-Oh-Midazolam-Glucuronide |
UidP |
Transport of D-Glucuronate 1-OH-midazolam-glucuronide |
1'-OH-midazolam-glucuronide[e] -> 1'-OH-midazolam-glucuronide[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
1'-Oh-Midazolam-Glucuronide |
1'-Oh-Midazolam-Glucuronide |
UidB |
Glucuronate transport in via proton symport 1-OH-midazolam-glucuronide |
1'-OH-midazolam-glucuronide[e] + h[e] -> 1'-OH-midazolam-glucuronide[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
1'-Oh-Midazolam-Glucuronide |
1'-Oh-Midazolam-Glucuronide |
UidB |
Glucuronate transport in via proton symport 1-OH-midazolam-glucuronide, periplasmatic |
1'-OH-midazolam-glucuronide[p] + h[p] -> 1'-OH-midazolam-glucuronide[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
1'-Oh-Midazolam-Glucuronide |
1'-Oh-Midazolam-Glucuronide |
n.a. |
1-OH-midazolam-glucuronide diffusion extracellular to periplasm |
1'-OH-midazolam-glucuronide[e] <=> 1'-OH-midazolam-glucuronide[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
1'-Oh-Midazolam |
1'-Oh-Midazolam |
n.a. |
beta-glucuronidase reaction product export 1-OH-midazolam |
1'-OH-midazolam[c] -> 1'-OH-midazolam[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Acidgluc |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Acid |
UidAc |
2-hydroxy-atorvastatin-acyl-glucuronide beta-glucuronidase |
2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin acidgluc[c] + h2o[c] -> 2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin acid[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01076 |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Acidgluc |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Acid |
UidAe |
2-hydroxy-atorvastatin-acyl-glucuronide beta-glucuronidase extracellular |
2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin acidgluc[e] + h2o[e] -> 2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin acid[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01076 |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Acidgluc |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Acid |
UidAe |
2-hydroxy-atorvastatin-acyl-glucuronide beta-glucuronidase extracellular, periplasmatic |
2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin acidgluc[p] + h2o[p] -> 2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin acid[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01076 |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Acidgluc |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Acidgluc |
UidABC |
Predicted glucuronide ABC transporter 2-hydroxy-atorvastatin-acyl-glucuronide |
atp[c] + 2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin acidgluc[e] + h2o[c] -> adp[c] + 2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin acidgluc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Acidgluc |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Acidgluc |
UidP |
Transport of D-Glucuronate 2-hydroxy-atorvastatin-acyl-glucuronide |
2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin acidgluc[e] -> 2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin acidgluc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Acidgluc |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Acidgluc |
UidB |
Glucuronate transport in via proton symport 2-hydroxy-atorvastatin-acyl-glucuronide |
2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin acidgluc[e] + h[e] -> 2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin acidgluc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Acidgluc |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Acidgluc |
UidB |
Glucuronate transport in via proton symport 2-hydroxy-atorvastatin-acyl-glucuronide, periplasmatic |
2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin acidgluc[p] + h[p] -> 2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin acidgluc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Acidgluc |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Acidgluc |
n.a. |
2-hydroxy-atorvastatin-acyl-glucuronide diffusion extracellular to periplasm |
2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin acidgluc[e] <=> 2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin acidgluc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Acid |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Acid |
n.a. |
beta-glucuronidase reaction product export 2-hydroxy-atorvastatin-acid / ortho-hydroxy-atorvastatin acid |
2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin acid[c] -> 2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin acid[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Acid |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Acid |
n.a. |
beta-glucuronidase reaction product export 2-hydroxy-atorvastatin-acid / ortho-hydroxy-atorvastatin acid, periplasmatic |
2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin acid[c] -> 2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin acid[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Acid |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Acid |
n.a. |
2-hydroxy-atorvastatin-acid / ortho-hydroxy-atorvastatin acid diffusion extracellular to periplasm |
2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin acid[e] <=> 2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin acid[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Lactonegluc |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Lactone |
UidAc |
2-hydroxy-atorvastatin-lactone-glucuronide beta-glucuronidase |
2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin lactonegluc[c] + h2o[c] -> 2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin lactone[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01076 |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Lactonegluc |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Lactone |
UidAe |
2-hydroxy-atorvastatin-lactone-glucuronide beta-glucuronidase extracellular |
2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin lactonegluc[e] + h2o[e] -> 2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin lactone[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01076 |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Lactonegluc |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Lactone |
UidAe |
2-hydroxy-atorvastatin-lactone-glucuronide beta-glucuronidase extracellular, periplasmatic |
2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin lactonegluc[p] + h2o[p] -> 2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin lactone[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01076 |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Lactonegluc |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Lactonegluc |
UidABC |
Predicted glucuronide ABC transporter 2-hydroxy-atorvastatin-lactone-glucuronide |
atp[c] + 2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin lactonegluc[e] + h2o[c] -> adp[c] + 2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin lactonegluc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Lactonegluc |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Lactonegluc |
UidP |
Transport of D-Glucuronate 2-hydroxy-atorvastatin-lactone-glucuronide |
2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin lactonegluc[e] -> 2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin lactonegluc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Lactonegluc |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Lactonegluc |
UidB |
Glucuronate transport in via proton symport 2-hydroxy-atorvastatin-lactone-glucuronide |
2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin lactonegluc[e] + h[e] -> 2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin lactonegluc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Lactonegluc |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Lactonegluc |
UidB |
Glucuronate transport in via proton symport 2-hydroxy-atorvastatin-lactone-glucuronide, periplasmatic |
2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin lactonegluc[p] + h[p] -> 2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin lactonegluc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Lactonegluc |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Lactonegluc |
n.a. |
2-hydroxy-atorvastatin-lactone-glucuronide diffusion extracellular to periplasm |
2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin lactonegluc[e] <=> 2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin lactonegluc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Lactone |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Lactone |
n.a. |
beta-glucuronidase reaction product export 2-hydroxy-atorvastatin-lactone / ortho-hydroxy-atorvastatin lactone |
2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin lactone[c] -> 2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin lactone[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Lactone |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Lactone |
n.a. |
beta-glucuronidase reaction product export 2-hydroxy-atorvastatin-lactone / ortho-hydroxy-atorvastatin lactone, periplasmatic |
2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin lactone[c] -> 2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin lactone[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Lactone |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Lactone |
n.a. |
2-hydroxy-atorvastatin-lactone / ortho-hydroxy-atorvastatin lactone diffusion extracellular to periplasm |
2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin lactone[e] <=> 2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin lactone[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
2-Hydroxy S-Ibuprofen-Glucuronide |
2-Hydroxy-S-Ibuprofen |
UidAc |
2-hydroxy-S-ibuprofen beta-glucuronidase |
2-hydroxy S-ibuprofen-glucuronide[c] + h2o[c] -> 2-hydroxy-S-ibuprofen[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01050 |
2-Hydroxy S-Ibuprofen-Glucuronide |
2-Hydroxy-S-Ibuprofen |
UidAe |
2-hydroxy-S-ibuprofen beta-glucuronidase extracellular |
2-hydroxy S-ibuprofen-glucuronide[e] + h2o[e] -> 2-hydroxy-S-ibuprofen[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01050 |
2-Hydroxy S-Ibuprofen-Glucuronide |
2-Hydroxy-S-Ibuprofen |
UidAe |
2-hydroxy-S-ibuprofen beta-glucuronidase extracellular, periplasmatic |
2-hydroxy S-ibuprofen-glucuronide[p] + h2o[p] -> 2-hydroxy-S-ibuprofen[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01050 |
2-Hydroxy-S-Ibuprofen |
2-Hydroxy-S-Ibuprofen |
UidABC |
Predicted glucuronide ABC transporter 2-hydroxy-S-ibuprofen |
atp[c] + 2-hydroxy-S-ibuprofen[e] + h2o[c] -> adp[c] + 2-hydroxy-S-ibuprofen[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
2-Hydroxy-S-Ibuprofen |
2-Hydroxy-S-Ibuprofen |
UidP |
Transport of D-Glucuronate 2-hydroxy-S-ibuprofen |
2-hydroxy-S-ibuprofen[e] -> 2-hydroxy-S-ibuprofen[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
2-Hydroxy-S-Ibuprofen |
2-Hydroxy-S-Ibuprofen |
UidB |
Glucuronate transport in via proton symport 2-hydroxy-S-ibuprofen |
2-hydroxy-S-ibuprofen[e] + h[e] -> 2-hydroxy-S-ibuprofen[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
2-Hydroxy-S-Ibuprofen |
2-Hydroxy-S-Ibuprofen |
UidP |
beta-glucuronidase reaction product export,2-hydroxy-S-ibuprofen, periplasmatic |
2-hydroxy-S-ibuprofen[c] -> 2-hydroxy-S-ibuprofen[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
2-Hydroxy-S-Ibuprofen |
2-Hydroxy-S-Ibuprofen |
n.a. |
2-hydroxy-S-ibuprofen diffusion extracellular to periplasm |
2-hydroxy-S-ibuprofen[e] <=> 2-hydroxy-S-ibuprofen[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
2-Hydroxy S-Ibuprofen-Glucuronide |
2-Hydroxy S-Ibuprofen-Glucuronide |
UidB |
Glucuronate transport in via proton symport (in),2-hydroxy S-ibuprofen-glucuronide, periplasmatic |
2-hydroxy S-ibuprofen-glucuronide[p] + h[p] -> 2-hydroxy S-ibuprofen-glucuronide[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
2-Hydroxy S-Ibuprofen-Glucuronide |
2-Hydroxy S-Ibuprofen-Glucuronide |
n.a. |
beta-glucuronidase reaction product export 2-hydroxy S-ibuprofen-glucuronide |
2-hydroxy S-ibuprofen-glucuronide[c] -> 2-hydroxy S-ibuprofen-glucuronide[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
2-Hydroxy S-Ibuprofen-Glucuronide |
2-Hydroxy S-Ibuprofen-Glucuronide |
n.a. |
2-hydroxy S-ibuprofen-glucuronide diffusion extracellular to periplasm |
2-hydroxy S-ibuprofen-glucuronide[e] <=> 2-hydroxy S-ibuprofen-glucuronide[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00564 |
2-Hydroxycarbamazepine_Glc |
2-Hydroxycarbamazepine |
UidAc |
2-Hydroxy Carbamazepine Glucuronide beta-glucuronidase |
2-Hydroxycarbamazepine_glc[c] + h2o[c] -> 2-Hydroxycarbamazepine[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00564 |
2-Hydroxycarbamazepine_Glc |
2-Hydroxycarbamazepine |
UidAe |
2-Hydroxy Carbamazepine Glucuronide beta-glucuronidase extracellular |
2-Hydroxycarbamazepine_glc[e] + h2o[e] -> 2-Hydroxycarbamazepine[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00564 |
2-Hydroxycarbamazepine_Glc |
2-Hydroxycarbamazepine |
UidAe |
2-Hydroxy Carbamazepine Glucuronide beta-glucuronidase extracellular, periplasmatic |
2-Hydroxycarbamazepine_glc[p] + h2o[p] -> 2-Hydroxycarbamazepine[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00564 |
2-Hydroxycarbamazepine_Glc |
2-Hydroxycarbamazepine_Glc |
UidABC |
Predicted glucuronide ABC transporter 2-Hydroxy Carbamazepine Glucuronide |
atp[c] + 2-Hydroxycarbamazepine_glc[e] + h2o[c] -> adp[c] + 2-Hydroxycarbamazepine_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00564 |
2-Hydroxycarbamazepine_Glc |
2-Hydroxycarbamazepine_Glc |
UidP |
Transport of D-Glucuronate 2-Hydroxy Carbamazepine Glucuronide |
2-Hydroxycarbamazepine_glc[e] -> 2-Hydroxycarbamazepine_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00564 |
2-Hydroxycarbamazepine_Glc |
2-Hydroxycarbamazepine_Glc |
UidB |
Glucuronate transport in via proton symport 2-Hydroxy Carbamazepine Glucuronide |
2-Hydroxycarbamazepine_glc[e] + h[e] -> 2-Hydroxycarbamazepine_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00564 |
2-Hydroxycarbamazepine_Glc |
2-Hydroxycarbamazepine_Glc |
UidB |
Glucuronate transport in via proton symport 2-Hydroxy Carbamazepine Glucuronide, periplasmatic |
2-Hydroxycarbamazepine_glc[p] + h[p] -> 2-Hydroxycarbamazepine_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00564 |
2-Hydroxycarbamazepine_Glc |
2-Hydroxycarbamazepine_Glc |
n.a. |
2-Hydroxy Carbamazepine Glucuronide diffusion extracellular to periplasm |
2-Hydroxycarbamazepine_glc[e] <=> 2-Hydroxycarbamazepine_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00564 |
2-Hydroxycarbamazepine |
2-Hydroxycarbamazepine |
n.a. |
beta-glucuronidase reaction product export 2-Hydroxycarbamazepine |
2-Hydroxycarbamazepine[c] -> 2-Hydroxycarbamazepine[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00564 |
2-Hydroxycarbamazepine |
2-Hydroxycarbamazepine |
n.a. |
beta-glucuronidase reaction product export 2-Hydroxycarbamazepine, periplasmatic |
2-Hydroxycarbamazepine[c] -> 2-Hydroxycarbamazepine[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00564 |
2-Hydroxycarbamazepine |
2-Hydroxycarbamazepine |
n.a. |
2-Hydroxycarbamazepine diffusion extracellular to periplasm |
2-Hydroxycarbamazepine[e] <=> 2-Hydroxycarbamazepine[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00916 |
2-Hydroxymetronidazole_Glc |
2-Hydroxymetronidazole |
UidAc |
2-Hydroxymetronidazole Glucuronide beta-glucuronidase |
2-Hydroxymetronidazole_glc[c] + h2o[c] -> 2-Hydroxymetronidazole[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00916 |
2-Hydroxymetronidazole_Glc |
2-Hydroxymetronidazole |
UidAe |
2-Hydroxymetronidazole Glucuronide beta-glucuronidase extracellular |
2-Hydroxymetronidazole_glc[e] + h2o[e] -> 2-Hydroxymetronidazole[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00916 |
2-Hydroxymetronidazole_Glc |
2-Hydroxymetronidazole |
UidAe |
2-Hydroxymetronidazole Glucuronide beta-glucuronidase extracellular, periplasmatic |
2-Hydroxymetronidazole_glc[p] + h2o[p] -> 2-Hydroxymetronidazole[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00916 |
2-Hydroxymetronidazole_Glc |
2-Hydroxymetronidazole_Glc |
UidABC |
Predicted glucuronide ABC transporter 2-Hydroxymetronidazole Glucuronide |
atp[c] + 2-Hydroxymetronidazole_glc[e] + h2o[c] -> adp[c] + 2-Hydroxymetronidazole_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00916 |
2-Hydroxymetronidazole_Glc |
2-Hydroxymetronidazole_Glc |
UidP |
Transport of D-Glucuronate 2-Hydroxymetronidazole Glucuronide |
2-Hydroxymetronidazole_glc[e] -> 2-Hydroxymetronidazole_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00916 |
2-Hydroxymetronidazole_Glc |
2-Hydroxymetronidazole_Glc |
UidB |
Glucuronate transport in via proton symport 2-Hydroxymetronidazole Glucuronide |
2-Hydroxymetronidazole_glc[e] + h[e] -> 2-Hydroxymetronidazole_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00916 |
2-Hydroxymetronidazole_Glc |
2-Hydroxymetronidazole_Glc |
UidB |
Glucuronate transport in via proton symport 2-Hydroxymetronidazole Glucuronide, periplasmatic |
2-Hydroxymetronidazole_glc[p] + h[p] -> 2-Hydroxymetronidazole_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00916 |
2-Hydroxymetronidazole_Glc |
2-Hydroxymetronidazole_Glc |
n.a. |
2-Hydroxymetronidazole Glucuronide diffusion extracellular to periplasm |
2-Hydroxymetronidazole_glc[e] <=> 2-Hydroxymetronidazole_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00916 |
2-Hydroxymetronidazole |
2-Hydroxymetronidazole |
n.a. |
beta-glucuronidase reaction product export 2-Hydroxymetronidazole |
2-Hydroxymetronidazole[c] -> 2-Hydroxymetronidazole[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00916 |
2-Hydroxymetronidazole |
2-Hydroxymetronidazole |
n.a. |
beta-glucuronidase reaction product export 2-Hydroxymetronidazole, periplasmatic |
2-Hydroxymetronidazole[c] -> 2-Hydroxymetronidazole[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00916 |
2-Hydroxymetronidazole |
2-Hydroxymetronidazole |
n.a. |
2-Hydroxymetronidazole diffusion extracellular to periplasm |
2-Hydroxymetronidazole[e] <=> 2-Hydroxymetronidazole[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01235 |
L-Dopamine |
L-Dopamine |
Tdc |
L-Dopa transport in via proton symport |
L-Dopamine[e] + h[e] -> L-Dopamine[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
3-Hydroxy S-Ibuprofen-Glucuronide |
3-Hydroxy S-Ibuprofen |
UidAc |
3-hydroxy S-ibuprofen beta-glucuronidase |
3-hydroxy S-ibuprofen-glucuronide[c] + h2o[c] -> 3-hydroxy S-ibuprofen[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01050 |
3-Hydroxy S-Ibuprofen-Glucuronide |
3-Hydroxy S-Ibuprofen |
UidAe |
3-hydroxy S-ibuprofen beta-glucuronidase extracellular |
3-hydroxy S-ibuprofen-glucuronide[e] + h2o[e] -> 3-hydroxy S-ibuprofen[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01050 |
3-Hydroxy S-Ibuprofen-Glucuronide |
3-Hydroxy S-Ibuprofen |
UidAe |
3-hydroxy S-ibuprofen beta-glucuronidase extracellular, periplasmatic |
3-hydroxy S-ibuprofen-glucuronide[p] + h2o[p] -> 3-hydroxy S-ibuprofen[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01050 |
3-Hydroxy S-Ibuprofen |
3-Hydroxy S-Ibuprofen |
UidABC |
Predicted glucuronide ABC transporter 3-hydroxy S-ibuprofen |
atp[c] + 3-hydroxy S-ibuprofen[e] + h2o[c] -> adp[c] + 3-hydroxy S-ibuprofen[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
3-Hydroxy S-Ibuprofen |
3-Hydroxy S-Ibuprofen |
UidP |
Transport of D-Glucuronate 3-hydroxy S-ibuprofen |
3-hydroxy S-ibuprofen[e] -> 3-hydroxy S-ibuprofen[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
3-Hydroxy S-Ibuprofen |
3-Hydroxy S-Ibuprofen |
UidB |
Glucuronate transport in via proton symport 3-hydroxy S-ibuprofen |
3-hydroxy S-ibuprofen[e] + h[e] -> 3-hydroxy S-ibuprofen[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
3-Hydroxy S-Ibuprofen |
3-Hydroxy S-Ibuprofen |
UidP |
beta-glucuronidase reaction product export,3-hydroxy S-ibuprofen, periplasmatic |
3-hydroxy S-ibuprofen[c] -> 3-hydroxy S-ibuprofen[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
3-Hydroxy S-Ibuprofen |
3-Hydroxy S-Ibuprofen |
n.a. |
3-hydroxy S-ibuprofen diffusion extracellular to periplasm |
3-hydroxy S-ibuprofen[e] <=> 3-hydroxy S-ibuprofen[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
3-Hydroxy S-Ibuprofen-Glucuronide |
3-Hydroxy S-Ibuprofen-Glucuronide |
UidB |
Glucuronate transport in via proton symport (in),3-hydroxy S-ibuprofen-glucuronide, periplasmatic |
3-hydroxy S-ibuprofen-glucuronide[p] + h[p] -> 3-hydroxy S-ibuprofen-glucuronide[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
3-Hydroxy S-Ibuprofen-Glucuronide |
3-Hydroxy S-Ibuprofen-Glucuronide |
n.a. |
beta-glucuronidase reaction product export 3-hydroxy S-ibuprofen-glucuronide |
3-hydroxy S-ibuprofen-glucuronide[c] -> 3-hydroxy S-ibuprofen-glucuronide[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
3-Hydroxy S-Ibuprofen-Glucuronide |
3-Hydroxy S-Ibuprofen-Glucuronide |
n.a. |
3-hydroxy S-ibuprofen-glucuronide diffusion extracellular to periplasm |
3-hydroxy S-ibuprofen-glucuronide[e] <=> 3-hydroxy S-ibuprofen-glucuronide[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01235 |
L-Dopamine |
Dopamine |
Tdc |
3-Hydroxy-L-Tyrosine Carboxy-Lyase |
L-Dopamine[c] + h[c] -> co2[c] + Dopamine[c] |
Tyrosine metabolism |
Metabolism |
Amino Acids and Derivatives |
Aromatic amino acids and derivatives |
Tyrosine metabolism |
PMID: 30659181 |
| n.a. |
3-Hydroxyphenylacetate |
N.A. |
n.a. |
3-Hydroxyphenylacetate diffusion extracellular to periplasm |
3hphac[e] <=> 3hphac[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Propionate |
N.A. |
n.a. |
3-(3-hydroxy-phenyl)propionate diffusion extracellular to periplasm |
3hpppn[e] <=> 3hpppn[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
3-Methoxy-Acetaminophen |
3-Methoxy-Acetaminophen |
n.a. |
beta-glucuronidase reaction product export 3-methoxy-acetaminophen |
3-methoxy-acetaminophen[c] -> 3-methoxy-acetaminophen[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
3-Methoxy-Acetaminophen |
3-Methoxy-Acetaminophen |
n.a. |
beta-glucuronidase reaction product export 3-methoxy-acetaminophen, periplasmatic |
3-methoxy-acetaminophen[c] -> 3-methoxy-acetaminophen[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
3-Methoxy-Acetaminophen |
3-Methoxy-Acetaminophen |
n.a. |
3-methoxy-acetaminophen diffusion extracellular to periplasm |
3-methoxy-acetaminophen[e] <=> 3-methoxy-acetaminophen[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00564 |
3-Hydroxycarbamazepine_Glc |
3-Hydroxycarbamazepine |
UidAc |
3-Hydroxy Carbamazepine Glucuronide beta-glucuronidase |
3-Hydroxycarbamazepine_glc[c] + h2o[c] -> 3-Hydroxycarbamazepine[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 30724669 |
| DB00564 |
3-Hydroxycarbamazepine_Glc |
3-Hydroxycarbamazepine |
UidAe |
3-Hydroxy Carbamazepine Glucuronide beta-glucuronidase extracellular |
3-Hydroxycarbamazepine_glc[e] + h2o[e] -> 3-Hydroxycarbamazepine[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 30724669 |
| DB00564 |
3-Hydroxycarbamazepine_Glc |
3-Hydroxycarbamazepine |
UidAe |
3-Hydroxy Carbamazepine Glucuronide beta-glucuronidase extracellular, periplasmatic |
3-Hydroxycarbamazepine_glc[p] + h2o[p] -> 3-Hydroxycarbamazepine[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00564 |
3-Hydroxycarbamazepine_Glc |
3-Hydroxycarbamazepine_Glc |
UidABC |
Predicted glucuronide ABC transporter 3-Hydroxy Carbamazepine Glucuronide |
atp[c] + 3-Hydroxycarbamazepine_glc[e] + h2o[c] -> adp[c] + 3-Hydroxycarbamazepine_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00564 |
3-Hydroxycarbamazepine_Glc |
3-Hydroxycarbamazepine_Glc |
UidP |
Transport of D-Glucuronate 3-Hydroxy Carbamazepine Glucuronide |
3-Hydroxycarbamazepine_glc[e] -> 3-Hydroxycarbamazepine_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00564 |
3-Hydroxycarbamazepine_Glc |
3-Hydroxycarbamazepine_Glc |
UidB |
Glucuronate transport in via proton symport 3-Hydroxy Carbamazepine Glucuronide |
3-Hydroxycarbamazepine_glc[e] + h[e] -> 3-Hydroxycarbamazepine_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00564 |
3-Hydroxycarbamazepine_Glc |
3-Hydroxycarbamazepine_Glc |
UidB |
Glucuronate transport in via proton symport 3-Hydroxy Carbamazepine Glucuronide, periplasmatic |
3-Hydroxycarbamazepine_glc[p] + h[p] -> 3-Hydroxycarbamazepine_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00564 |
3-Hydroxycarbamazepine_Glc |
3-Hydroxycarbamazepine_Glc |
n.a. |
3-Hydroxy Carbamazepine Glucuronide diffusion extracellular to periplasm |
3-Hydroxycarbamazepine_glc[e] <=> 3-Hydroxycarbamazepine_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00564 |
3-Hydroxycarbamazepine |
3-Hydroxycarbamazepine |
n.a. |
beta-glucuronidase reaction product export 3-Hydroxycarbamazepine |
3-Hydroxycarbamazepine[c] -> 3-Hydroxycarbamazepine[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00564 |
3-Hydroxycarbamazepine |
3-Hydroxycarbamazepine |
n.a. |
beta-glucuronidase reaction product export 3-Hydroxycarbamazepine, periplasmatic |
3-Hydroxycarbamazepine[c] -> 3-Hydroxycarbamazepine[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00564 |
3-Hydroxycarbamazepine |
3-Hydroxycarbamazepine |
n.a. |
3-Hydroxycarbamazepine diffusion extracellular to periplasm |
3-Hydroxycarbamazepine[e] <=> 3-Hydroxycarbamazepine[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00967 |
3-Hydroxydesloratadine_Glc |
3-Hydroxydesloratadine |
UidAc |
3-Hydroxydesloratadine Glucuronide beta-glucuronidase |
3-Hydroxydesloratadine_glc[c] + h2o[c] -> 3-Hydroxydesloratadine[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00967 |
3-Hydroxydesloratadine_Glc |
3-Hydroxydesloratadine |
UidAe |
3-Hydroxydesloratadine Glucuronide beta-glucuronidase extracellular |
3-Hydroxydesloratadine_glc[e] + h2o[e] -> 3-Hydroxydesloratadine[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00967 |
3-Hydroxydesloratadine_Glc |
3-Hydroxydesloratadine |
UidAe |
3-Hydroxydesloratadine Glucuronide beta-glucuronidase extracellular, periplasmatic |
3-Hydroxydesloratadine_glc[p] + h2o[p] -> 3-Hydroxydesloratadine[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00967 |
3-Hydroxydesloratadine_Glc |
3-Hydroxydesloratadine_Glc |
UidABC |
Predicted glucuronide ABC transporter 3-Hydroxydesloratadine Glucuronide |
atp[c] + 3-Hydroxydesloratadine_glc[e] + h2o[c] -> adp[c] + 3-Hydroxydesloratadine_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00967 |
3-Hydroxydesloratadine_Glc |
3-Hydroxydesloratadine_Glc |
UidP |
Transport of D-Glucuronate 3-Hydroxydesloratadine Glucuronide |
3-Hydroxydesloratadine_glc[e] -> 3-Hydroxydesloratadine_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00967 |
3-Hydroxydesloratadine_Glc |
3-Hydroxydesloratadine_Glc |
UidB |
Glucuronate transport in via proton symport 3-Hydroxydesloratadine Glucuronide |
3-Hydroxydesloratadine_glc[e] + h[e] -> 3-Hydroxydesloratadine_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00967 |
3-Hydroxydesloratadine_Glc |
3-Hydroxydesloratadine_Glc |
UidB |
Glucuronate transport in via proton symport 3-Hydroxydesloratadine Glucuronide, periplasmatic |
3-Hydroxydesloratadine_glc[p] + h[p] -> 3-Hydroxydesloratadine_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00967 |
3-Hydroxydesloratadine_Glc |
3-Hydroxydesloratadine_Glc |
n.a. |
3-Hydroxydesloratadine Glucuronide diffusion extracellular to periplasm |
3-Hydroxydesloratadine_glc[e] <=> 3-Hydroxydesloratadine_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00967 |
3-Hydroxydesloratadine |
3-Hydroxydesloratadine |
n.a. |
beta-glucuronidase reaction product export 3-Hydroxydesloratadine |
3-Hydroxydesloratadine[c] -> 3-Hydroxydesloratadine[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00967 |
3-Hydroxydesloratadine |
3-Hydroxydesloratadine |
n.a. |
beta-glucuronidase reaction product export 3-Hydroxydesloratadine, periplasmatic |
3-Hydroxydesloratadine[c] -> 3-Hydroxydesloratadine[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00967 |
3-Hydroxydesloratadine |
3-Hydroxydesloratadine |
n.a. |
3-Hydroxydesloratadine diffusion extracellular to periplasm |
3-Hydroxydesloratadine[e] <=> 3-Hydroxydesloratadine[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
3-Hydroxy N-Desethylamiodaronedarone (3-Hydroxy_Mdea) (M8)_Glc |
3-Hydroxy N-Desethylamiodaronedarone (3-Hydroxy_Mdea) (M8) |
UidAc |
3-Hydroxy N-Desethylamiodarone Glucuronide (3-Hydroxy_MDEA_Glc) (M15) beta-glucuronidase |
3-Hydroxy N-DesethylAmiodaronedarone (3-Hydroxy_MDEA) (M8)_glc[c] + h2o[c] -> 3-Hydroxy N-DesethylAmiodaronedarone (3-Hydroxy_MDEA) (M8)[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01118 |
3-Hydroxy N-Desethylamiodaronedarone (3-Hydroxy_Mdea) (M8)_Glc |
3-Hydroxy N-Desethylamiodaronedarone (3-Hydroxy_Mdea) (M8) |
UidAe |
3-Hydroxy N-Desethylamiodarone Glucuronide (3-Hydroxy_MDEA_Glc) (M15) beta-glucuronidase extracellular |
3-Hydroxy N-DesethylAmiodaronedarone (3-Hydroxy_MDEA) (M8)_glc[e] + h2o[e] -> 3-Hydroxy N-DesethylAmiodaronedarone (3-Hydroxy_MDEA) (M8)[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01118 |
3-Hydroxy N-Desethylamiodaronedarone (3-Hydroxy_Mdea) (M8)_Glc |
3-Hydroxy N-Desethylamiodaronedarone (3-Hydroxy_Mdea) (M8) |
UidAe |
3-Hydroxy N-Desethylamiodarone Glucuronide (3-Hydroxy_MDEA_Glc) (M15) beta-glucuronidase extracellular, periplasmatic |
3-Hydroxy N-DesethylAmiodaronedarone (3-Hydroxy_MDEA) (M8)_glc[p] + h2o[p] -> 3-Hydroxy N-DesethylAmiodaronedarone (3-Hydroxy_MDEA) (M8)[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01118 |
3-Hydroxy N-Desethylamiodaronedarone (3-Hydroxy_Mdea) (M8)_Glc |
3-Hydroxy N-Desethylamiodaronedarone (3-Hydroxy_Mdea) (M8)_Glc |
UidABC |
Predicted glucuronide ABC transporter 3-Hydroxy N-Desethylamiodarone Glucuronide (3-Hydroxy_MDEA_Glc) (M15) |
atp[c] + 3-Hydroxy N-DesethylAmiodaronedarone (3-Hydroxy_MDEA) (M8)_glc[e] + h2o[c] -> adp[c] + 3-Hydroxy N-DesethylAmiodaronedarone (3-Hydroxy_MDEA) (M8)_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
3-Hydroxy N-Desethylamiodaronedarone (3-Hydroxy_Mdea) (M8)_Glc |
3-Hydroxy N-Desethylamiodaronedarone (3-Hydroxy_Mdea) (M8)_Glc |
UidP |
Transport of D-Glucuronate 3-Hydroxy N-Desethylamiodarone Glucuronide (3-Hydroxy_MDEA_Glc) (M15) |
3-Hydroxy N-DesethylAmiodaronedarone (3-Hydroxy_MDEA) (M8)_glc[e] -> 3-Hydroxy N-DesethylAmiodaronedarone (3-Hydroxy_MDEA) (M8)_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
3-Hydroxy N-Desethylamiodaronedarone (3-Hydroxy_Mdea) (M8)_Glc |
3-Hydroxy N-Desethylamiodaronedarone (3-Hydroxy_Mdea) (M8)_Glc |
UidB |
Glucuronate transport in via proton symport 3-Hydroxy N-Desethylamiodarone Glucuronide (3-Hydroxy_MDEA_Glc) (M15) |
3-Hydroxy N-DesethylAmiodaronedarone (3-Hydroxy_MDEA) (M8)_glc[e] + h[e] -> 3-Hydroxy N-DesethylAmiodaronedarone (3-Hydroxy_MDEA) (M8)_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
3-Hydroxy N-Desethylamiodaronedarone (3-Hydroxy_Mdea) (M8)_Glc |
3-Hydroxy N-Desethylamiodaronedarone (3-Hydroxy_Mdea) (M8)_Glc |
UidB |
Glucuronate transport in via proton symport 3-Hydroxy N-Desethylamiodarone Glucuronide (3-Hydroxy_MDEA_Glc) (M15), periplasmatic |
3-Hydroxy N-DesethylAmiodaronedarone (3-Hydroxy_MDEA) (M8)_glc[p] + h[p] -> 3-Hydroxy N-DesethylAmiodaronedarone (3-Hydroxy_MDEA) (M8)_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
3-Hydroxy N-Desethylamiodaronedarone (3-Hydroxy_Mdea) (M8)_Glc |
3-Hydroxy N-Desethylamiodaronedarone (3-Hydroxy_Mdea) (M8)_Glc |
n.a. |
3-Hydroxy N-Desethylamiodarone Glucuronide (3-Hydroxy_MDEA_Glc) (M15) diffusion extracellular to periplasm |
3-Hydroxy N-DesethylAmiodaronedarone (3-Hydroxy_MDEA) (M8)_glc[e] <=> 3-Hydroxy N-DesethylAmiodaronedarone (3-Hydroxy_MDEA) (M8)_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
3-Hydroxy N-Desethylamiodaronedarone (3-Hydroxy_Mdea) (M8) |
3-Hydroxy N-Desethylamiodaronedarone (3-Hydroxy_Mdea) (M8) |
n.a. |
beta-glucuronidase reaction product export 3-Hydroxy N-Desethylamiodarone (3-Hydroxy_MDEA) (M8) |
3-Hydroxy N-DesethylAmiodaronedarone (3-Hydroxy_MDEA) (M8)[c] -> 3-Hydroxy N-DesethylAmiodaronedarone (3-Hydroxy_MDEA) (M8)[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
3-Hydroxy N-Desethylamiodaronedarone (3-Hydroxy_Mdea) (M8) |
3-Hydroxy N-Desethylamiodaronedarone (3-Hydroxy_Mdea) (M8) |
n.a. |
beta-glucuronidase reaction product export 3-Hydroxy N-Desethylamiodarone (3-Hydroxy_MDEA) (M8), periplasmatic |
3-Hydroxy N-DesethylAmiodaronedarone (3-Hydroxy_MDEA) (M8)[c] -> 3-Hydroxy N-DesethylAmiodaronedarone (3-Hydroxy_MDEA) (M8)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
3-Hydroxy N-Desethylamiodaronedarone (3-Hydroxy_Mdea) (M8) |
3-Hydroxy N-Desethylamiodaronedarone (3-Hydroxy_Mdea) (M8) |
n.a. |
3-Hydroxy N-Desethylamiodarone (3-Hydroxy_MDEA) (M8) diffusion extracellular to periplasm |
3-Hydroxy N-DesethylAmiodaronedarone (3-Hydroxy_MDEA) (M8)[e] <=> 3-Hydroxy N-DesethylAmiodaronedarone (3-Hydroxy_MDEA) (M8)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
3-Hydroxymorphinan_Glc |
3-Hydroxymorphinan |
UidAc |
3-Hydroxymorphinan O-Glucuronide beta-glucuronidase |
3-Hydroxymorphinan_glc[c] + h2o[c] -> 3-Hydroxymorphinan[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
3-Hydroxymorphinan_Glc |
3-Hydroxymorphinan |
UidAe |
3-Hydroxymorphinan O-Glucuronide beta-glucuronidase extracellular |
3-Hydroxymorphinan_glc[e] + h2o[e] -> 3-Hydroxymorphinan[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
3-Hydroxymorphinan_Glc |
3-Hydroxymorphinan |
UidAe |
3-Hydroxymorphinan O-Glucuronide beta-glucuronidase extracellular, periplasmatic |
3-Hydroxymorphinan_glc[p] + h2o[p] -> 3-Hydroxymorphinan[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
3-Hydroxymorphinan_Glc |
3-Hydroxymorphinan_Glc |
UidABC |
Predicted glucuronide ABC transporter 3-Hydroxymorphinan O-Glucuronide |
atp[c] + 3-Hydroxymorphinan_glc[e] + h2o[c] -> adp[c] + 3-Hydroxymorphinan_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
3-Hydroxymorphinan_Glc |
3-Hydroxymorphinan_Glc |
UidP |
Transport of D-Glucuronate 3-Hydroxymorphinan O-Glucuronide |
3-Hydroxymorphinan_glc[e] -> 3-Hydroxymorphinan_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
3-Hydroxymorphinan_Glc |
3-Hydroxymorphinan_Glc |
UidB |
Glucuronate transport in via proton symport 3-Hydroxymorphinan O-Glucuronide |
3-Hydroxymorphinan_glc[e] + h[e] -> 3-Hydroxymorphinan_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
3-Hydroxymorphinan_Glc |
3-Hydroxymorphinan_Glc |
UidB |
Glucuronate transport in via proton symport 3-Hydroxymorphinan O-Glucuronide, periplasmatic |
3-Hydroxymorphinan_glc[p] + h[p] -> 3-Hydroxymorphinan_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
3-Hydroxymorphinan_Glc |
3-Hydroxymorphinan_Glc |
n.a. |
3-Hydroxymorphinan O-Glucuronide diffusion extracellular to periplasm |
3-Hydroxymorphinan_glc[e] <=> 3-Hydroxymorphinan_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
3-Hydroxymorphinan |
3-Hydroxymorphinan |
n.a. |
beta-glucuronidase reaction product export 3-Hydroxymorphinan |
3-Hydroxymorphinan[c] -> 3-Hydroxymorphinan[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
3-Hydroxymorphinan |
3-Hydroxymorphinan |
n.a. |
beta-glucuronidase reaction product export 3-Hydroxymorphinan, periplasmatic |
3-Hydroxymorphinan[c] -> 3-Hydroxymorphinan[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
3-Hydroxymorphinan |
3-Hydroxymorphinan |
n.a. |
3-Hydroxymorphinan diffusion extracellular to periplasm |
3-Hydroxymorphinan[e] <=> 3-Hydroxymorphinan[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB12449 |
4-Dehydroxytempol_1Glc |
4-Dehydroxytempol |
UidAc |
4-Dehydroxytempol 1-O-Glucuronide beta-glucuronidase |
4-Dehydroxytempol_1glc[c] + h2o[c] -> 4-Dehydroxytempol[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB12449 |
4-Dehydroxytempol_1Glc |
4-Dehydroxytempol |
UidAe |
4-Dehydroxytempol 1-O-Glucuronide beta-glucuronidase extracellular |
4-Dehydroxytempol_1glc[e] + h2o[e] -> 4-Dehydroxytempol[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB12449 |
4-Dehydroxytempol_1Glc |
4-Dehydroxytempol_1Glc |
UidABC |
Predicted glucuronide ABC transporter 4-Dehydroxytempol 1-O-Glucuronide |
atp[c] + 4-Dehydroxytempol_1glc[e] + h2o[c] -> adp[c] + 4-Dehydroxytempol_1glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB12449 |
4-Dehydroxytempol_1Glc |
4-Dehydroxytempol_1Glc |
UidP |
Transport of D-Glucuronate 4-Dehydroxytempol 1-O-Glucuronide |
4-Dehydroxytempol_1glc[e] -> 4-Dehydroxytempol_1glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB12449 |
4-Dehydroxytempol_1Glc |
4-Dehydroxytempol_1Glc |
UidB |
Glucuronate transport in via proton symport 4-Dehydroxytempol 1-O-Glucuronide |
4-Dehydroxytempol_1glc[e] + h[e] -> 4-Dehydroxytempol_1glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB12449 |
4-Dehydroxytempol |
4-Dehydroxytempol |
n.a. |
beta-glucuronidase reaction product export 4-Dehydroxytempol |
4-Dehydroxytempol[c] -> 4-Dehydroxytempol[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
4-Oh-Midazolam-Glucuronide |
4-Oh-Midazolam |
UidAc |
4-OH-midazolam-glucuronide beta-glucuronidase |
4-OH-midazolam-glucuronide[c] + h2o[c] -> 4-OH-midazolam[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00683 |
4-Oh-Midazolam-Glucuronide |
4-Oh-Midazolam |
UidAe |
4-OH-midazolam-glucuronide beta-glucuronidase extracellular |
4-OH-midazolam-glucuronide[e] + h2o[e] -> 4-OH-midazolam[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00683 |
4-Oh-Midazolam-Glucuronide |
4-Oh-Midazolam |
UidAe |
4-OH-midazolam-glucuronide beta-glucuronidase extracellular, periplasmatic |
4-OH-midazolam-glucuronide[p] + h2o[p] -> 4-OH-midazolam[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00683 |
4-Oh-Midazolam-Glucuronide |
4-Oh-Midazolam-Glucuronide |
UidABC |
Predicted glucuronide ABC transporter 4-OH-midazolam-glucuronide |
atp[c] + 4-OH-midazolam-glucuronide[e] + h2o[c] -> adp[c] + 4-OH-midazolam-glucuronide[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
4-Oh-Midazolam-Glucuronide |
4-Oh-Midazolam-Glucuronide |
UidP |
Transport of D-Glucuronate 4-OH-midazolam-glucuronide |
4-OH-midazolam-glucuronide[e] -> 4-OH-midazolam-glucuronide[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
4-Oh-Midazolam-Glucuronide |
4-Oh-Midazolam-Glucuronide |
UidB |
Glucuronate transport in via proton symport 4-OH-midazolam-glucuronide |
4-OH-midazolam-glucuronide[e] + h[e] -> 4-OH-midazolam-glucuronide[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
4-Oh-Midazolam-Glucuronide |
4-Oh-Midazolam-Glucuronide |
UidB |
Glucuronate transport in via proton symport 4-OH-midazolam-glucuronide, periplasmatic |
4-OH-midazolam-glucuronide[p] + h[p] -> 4-OH-midazolam-glucuronide[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
4-Oh-Midazolam-Glucuronide |
4-Oh-Midazolam-Glucuronide |
n.a. |
4-OH-midazolam-glucuronide diffusion extracellular to periplasm |
4-OH-midazolam-glucuronide[e] <=> 4-OH-midazolam-glucuronide[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
N.A. |
P-Cresol |
Hpd |
4-hydroxyphenylacetate decarboxylase |
4hphac[c] -> co2[c] + p-Cresol[c] |
Tyrosine metabolism |
Metabolism |
Amino Acids and Derivatives |
Aromatic amino acids and derivatives |
Tyrosine metabolism |
PMID: 7026235 |
| DB00586 |
4-Hydroxydiclofenac_Glc |
4-Hydroxydiclofenac |
UidAc |
4-Hydroxydiclofenac Glucuronide beta-glucuronidase |
4-Hydroxydiclofenac_glc[c] + h2o[c] -> 4-Hydroxydiclofenac[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00586 |
4-Hydroxydiclofenac_Glc |
4-Hydroxydiclofenac |
UidAe |
4-Hydroxydiclofenac Glucuronide beta-glucuronidase extracellular |
4-Hydroxydiclofenac_glc[e] + h2o[e] -> 4-Hydroxydiclofenac[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00586 |
4-Hydroxydiclofenac_Glc |
4-Hydroxydiclofenac |
UidAe |
4-Hydroxydiclofenac Glucuronide beta-glucuronidase extracellular, periplasmatic |
4-Hydroxydiclofenac_glc[p] + h2o[p] -> 4-Hydroxydiclofenac[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00586 |
4-Hydroxydiclofenac_Glc |
4-Hydroxydiclofenac_Glc |
UidABC |
Predicted glucuronide ABC transporter 4-Hydroxydiclofenac Glucuronide |
atp[c] + 4-Hydroxydiclofenac_glc[e] + h2o[c] -> adp[c] + 4-Hydroxydiclofenac_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00586 |
4-Hydroxydiclofenac_Glc |
4-Hydroxydiclofenac_Glc |
UidP |
Transport of D-Glucuronate 4-Hydroxydiclofenac Glucuronide |
4-Hydroxydiclofenac_glc[e] -> 4-Hydroxydiclofenac_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00586 |
4-Hydroxydiclofenac_Glc |
4-Hydroxydiclofenac_Glc |
UidB |
Glucuronate transport in via proton symport 4-Hydroxydiclofenac Glucuronide |
4-Hydroxydiclofenac_glc[e] + h[e] -> 4-Hydroxydiclofenac_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00586 |
4-Hydroxydiclofenac_Glc |
4-Hydroxydiclofenac_Glc |
UidB |
Glucuronate transport in via proton symport 4-Hydroxydiclofenac Glucuronide, periplasmatic |
4-Hydroxydiclofenac_glc[p] + h[p] -> 4-Hydroxydiclofenac_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00586 |
4-Hydroxydiclofenac_Glc |
4-Hydroxydiclofenac_Glc |
n.a. |
4-Hydroxydiclofenac Glucuronide diffusion extracellular to periplasm |
4-Hydroxydiclofenac_glc[e] <=> 4-Hydroxydiclofenac_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00586 |
4-Hydroxydiclofenac |
4-Hydroxydiclofenac |
n.a. |
beta-glucuronidase reaction product export 4-Hydroxydiclofenac |
4-Hydroxydiclofenac[c] -> 4-Hydroxydiclofenac[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00586 |
4-Hydroxydiclofenac |
4-Hydroxydiclofenac |
n.a. |
beta-glucuronidase reaction product export 4-Hydroxydiclofenac, periplasmatic |
4-Hydroxydiclofenac[c] -> 4-Hydroxydiclofenac[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00586 |
4-Hydroxydiclofenac |
4-Hydroxydiclofenac |
n.a. |
4-Hydroxydiclofenac diffusion extracellular to periplasm |
4-Hydroxydiclofenac[e] <=> 4-Hydroxydiclofenac[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01009 |
4-Hydroxybenzyl Ketoprofen_Glc |
4-Hydroxybenzyl Ketoprofen |
UidAc |
4-Hydroxybenzyl Ketoprofen Glucuronide beta-glucuronidase |
4-Hydroxybenzyl Ketoprofen_glc[c] + h2o[c] -> 4-Hydroxybenzyl Ketoprofen[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01009 |
4-Hydroxybenzyl Ketoprofen_Glc |
4-Hydroxybenzyl Ketoprofen |
UidAe |
4-Hydroxybenzyl Ketoprofen Glucuronide beta-glucuronidase extracellular |
4-Hydroxybenzyl Ketoprofen_glc[e] + h2o[e] -> 4-Hydroxybenzyl Ketoprofen[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01009 |
4-Hydroxybenzyl Ketoprofen_Glc |
4-Hydroxybenzyl Ketoprofen |
UidAe |
4-Hydroxybenzyl Ketoprofen Glucuronide beta-glucuronidase extracellular, periplasmatic |
4-Hydroxybenzyl Ketoprofen_glc[p] + h2o[p] -> 4-Hydroxybenzyl Ketoprofen[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01009 |
4-Hydroxybenzyl Ketoprofen_Glc |
4-Hydroxybenzyl Ketoprofen_Glc |
UidABC |
Predicted glucuronide ABC transporter 4-Hydroxybenzyl Ketoprofen Glucuronide |
atp[c] + 4-Hydroxybenzyl Ketoprofen_glc[e] + h2o[c] -> adp[c] + 4-Hydroxybenzyl Ketoprofen_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01009 |
4-Hydroxybenzyl Ketoprofen_Glc |
4-Hydroxybenzyl Ketoprofen_Glc |
UidP |
Transport of D-Glucuronate 4-Hydroxybenzyl Ketoprofen Glucuronide |
4-Hydroxybenzyl Ketoprofen_glc[e] -> 4-Hydroxybenzyl Ketoprofen_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01009 |
4-Hydroxybenzyl Ketoprofen_Glc |
4-Hydroxybenzyl Ketoprofen_Glc |
UidB |
Glucuronate transport in via proton symport 4-Hydroxybenzyl Ketoprofen Glucuronide |
4-Hydroxybenzyl Ketoprofen_glc[e] + h[e] -> 4-Hydroxybenzyl Ketoprofen_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01009 |
4-Hydroxybenzyl Ketoprofen_Glc |
4-Hydroxybenzyl Ketoprofen_Glc |
UidB |
Glucuronate transport in via proton symport 4-Hydroxybenzyl Ketoprofen Glucuronide, periplasmatic |
4-Hydroxybenzyl Ketoprofen_glc[p] + h[p] -> 4-Hydroxybenzyl Ketoprofen_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01009 |
4-Hydroxybenzyl Ketoprofen_Glc |
4-Hydroxybenzyl Ketoprofen_Glc |
n.a. |
4-Hydroxybenzyl Ketoprofen Glucuronide diffusion extracellular to periplasm |
4-Hydroxybenzyl Ketoprofen_glc[e] <=> 4-Hydroxybenzyl Ketoprofen_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01009 |
4-Hydroxybenzyl Ketoprofen |
4-Hydroxybenzyl Ketoprofen |
n.a. |
beta-glucuronidase reaction product export 4-Hydroxybenzyl Ketoprofen |
4-Hydroxybenzyl Ketoprofen[c] -> 4-Hydroxybenzyl Ketoprofen[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01009 |
4-Hydroxybenzyl Ketoprofen |
4-Hydroxybenzyl Ketoprofen |
n.a. |
beta-glucuronidase reaction product export 4-Hydroxybenzyl Ketoprofen, periplasmatic |
4-Hydroxybenzyl Ketoprofen[c] -> 4-Hydroxybenzyl Ketoprofen[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01009 |
4-Hydroxybenzyl Ketoprofen |
4-Hydroxybenzyl Ketoprofen |
n.a. |
4-Hydroxybenzyl Ketoprofen diffusion extracellular to periplasm |
4-Hydroxybenzyl Ketoprofen[e] <=> 4-Hydroxybenzyl Ketoprofen[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB11596 |
4-Hydroxy Levamisonidazolele (M1)_Glc |
4-Hydroxy Levamisonidazolele (M1) |
UidAc |
4-Hydroxy Levamisole Glucuronide beta-glucuronidase |
4-Hydroxy LevaMisonidazolele (M1)_glc[c] + h2o[c] -> 4-Hydroxy LevaMisonidazolele (M1)[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB11596 |
4-Hydroxy Levamisonidazolele (M1)_Glc |
4-Hydroxy Levamisonidazolele (M1) |
UidAe |
4-Hydroxy Levamisole Glucuronide beta-glucuronidase extracellular |
4-Hydroxy LevaMisonidazolele (M1)_glc[e] + h2o[e] -> 4-Hydroxy LevaMisonidazolele (M1)[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB11596 |
4-Hydroxy Levamisonidazolele (M1)_Glc |
4-Hydroxy Levamisonidazolele (M1) |
UidAe |
4-Hydroxy Levamisole Glucuronide beta-glucuronidase extracellular, periplasmatic |
4-Hydroxy LevaMisonidazolele (M1)_glc[p] + h2o[p] -> 4-Hydroxy LevaMisonidazolele (M1)[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB11596 |
4-Hydroxy Levamisonidazolele (M1)_Glc |
4-Hydroxy Levamisonidazolele (M1)_Glc |
UidABC |
Predicted glucuronide ABC transporter 4-Hydroxy Levamisole Glucuronide |
atp[c] + 4-Hydroxy LevaMisonidazolele (M1)_glc[e] + h2o[c] -> adp[c] + 4-Hydroxy LevaMisonidazolele (M1)_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB11596 |
4-Hydroxy Levamisonidazolele (M1)_Glc |
4-Hydroxy Levamisonidazolele (M1)_Glc |
UidP |
Transport of D-Glucuronate 4-Hydroxy Levamisole Glucuronide |
4-Hydroxy LevaMisonidazolele (M1)_glc[e] -> 4-Hydroxy LevaMisonidazolele (M1)_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB11596 |
4-Hydroxy Levamisonidazolele (M1)_Glc |
4-Hydroxy Levamisonidazolele (M1)_Glc |
UidB |
Glucuronate transport in via proton symport 4-Hydroxy Levamisole Glucuronide |
4-Hydroxy LevaMisonidazolele (M1)_glc[e] + h[e] -> 4-Hydroxy LevaMisonidazolele (M1)_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB11596 |
4-Hydroxy Levamisonidazolele (M1)_Glc |
4-Hydroxy Levamisonidazolele (M1)_Glc |
UidB |
Glucuronate transport in via proton symport 4-Hydroxy Levamisole Glucuronide, periplasmatic |
4-Hydroxy LevaMisonidazolele (M1)_glc[p] + h[p] -> 4-Hydroxy LevaMisonidazolele (M1)_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB11596 |
4-Hydroxy Levamisonidazolele (M1)_Glc |
4-Hydroxy Levamisonidazolele (M1)_Glc |
n.a. |
4-Hydroxy Levamisole Glucuronide diffusion extracellular to periplasm |
4-Hydroxy LevaMisonidazolele (M1)_glc[e] <=> 4-Hydroxy LevaMisonidazolele (M1)_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB11596 |
4-Hydroxy Levamisonidazolele (M1) |
4-Hydroxy Levamisonidazolele (M1) |
n.a. |
beta-glucuronidase reaction product export 4-Hydroxy Levamisole (M1) |
4-Hydroxy LevaMisonidazolele (M1)[c] -> 4-Hydroxy LevaMisonidazolele (M1)[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB11596 |
4-Hydroxy Levamisonidazolele (M1) |
4-Hydroxy Levamisonidazolele (M1) |
n.a. |
beta-glucuronidase reaction product export 4-Hydroxy Levamisole (M1), periplasmatic |
4-Hydroxy LevaMisonidazolele (M1)[c] -> 4-Hydroxy LevaMisonidazolele (M1)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB11596 |
4-Hydroxy Levamisonidazolele (M1) |
4-Hydroxy Levamisonidazolele (M1) |
n.a. |
4-Hydroxy Levamisole (M1) diffusion extracellular to periplasm |
4-Hydroxy LevaMisonidazolele (M1)[e] <=> 4-Hydroxy LevaMisonidazolele (M1)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01577 |
4-Hydroxymethamphetamine_Glc |
4-Hydroxymethamphetamine |
UidAc |
4-Hydroxymethamphetamine Glucuronide beta-glucuronidase |
4-Hydroxymethamphetamine_glc[c] + h2o[c] -> 4-Hydroxymethamphetamine[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01577 |
4-Hydroxymethamphetamine_Glc |
4-Hydroxymethamphetamine |
UidAe |
4-Hydroxymethamphetamine Glucuronide beta-glucuronidase extracellular |
4-Hydroxymethamphetamine_glc[e] + h2o[e] -> 4-Hydroxymethamphetamine[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01577 |
4-Hydroxymethamphetamine_Glc |
4-Hydroxymethamphetamine |
UidAe |
4-Hydroxymethamphetamine Glucuronide beta-glucuronidase extracellular, periplasmatic |
4-Hydroxymethamphetamine_glc[p] + h2o[p] -> 4-Hydroxymethamphetamine[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01577 |
4-Hydroxymethamphetamine_Glc |
4-Hydroxymethamphetamine_Glc |
UidABC |
Predicted glucuronide ABC transporter 4-Hydroxymethamphetamine Glucuronide |
atp[c] + 4-Hydroxymethamphetamine_glc[e] + h2o[c] -> adp[c] + 4-Hydroxymethamphetamine_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01577 |
4-Hydroxymethamphetamine_Glc |
4-Hydroxymethamphetamine_Glc |
UidP |
Transport of D-Glucuronate 4-Hydroxymethamphetamine Glucuronide |
4-Hydroxymethamphetamine_glc[e] -> 4-Hydroxymethamphetamine_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01577 |
4-Hydroxymethamphetamine_Glc |
4-Hydroxymethamphetamine_Glc |
UidB |
Glucuronate transport in via proton symport 4-Hydroxymethamphetamine Glucuronide |
4-Hydroxymethamphetamine_glc[e] + h[e] -> 4-Hydroxymethamphetamine_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01577 |
4-Hydroxymethamphetamine_Glc |
4-Hydroxymethamphetamine_Glc |
UidB |
Glucuronate transport in via proton symport 4-Hydroxymethamphetamine Glucuronide, periplasmatic |
4-Hydroxymethamphetamine_glc[p] + h[p] -> 4-Hydroxymethamphetamine_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01577 |
4-Hydroxymethamphetamine_Glc |
4-Hydroxymethamphetamine_Glc |
n.a. |
4-Hydroxymethamphetamine Glucuronide diffusion extracellular to periplasm |
4-Hydroxymethamphetamine_glc[e] <=> 4-Hydroxymethamphetamine_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01577 |
4-Hydroxymethamphetamine |
4-Hydroxymethamphetamine |
n.a. |
beta-glucuronidase reaction product export 4-Hydroxymethamphetamine |
4-Hydroxymethamphetamine[c] -> 4-Hydroxymethamphetamine[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01577 |
4-Hydroxymethamphetamine |
4-Hydroxymethamphetamine |
n.a. |
beta-glucuronidase reaction product export 4-Hydroxymethamphetamine, periplasmatic |
4-Hydroxymethamphetamine[c] -> 4-Hydroxymethamphetamine[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01577 |
4-Hydroxymethamphetamine |
4-Hydroxymethamphetamine |
n.a. |
4-Hydroxymethamphetamine diffusion extracellular to periplasm |
4-Hydroxymethamphetamine[e] <=> 4-Hydroxymethamphetamine[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00571 |
4-Hydroxypropanolol_Glc |
4-Hydroxypropanolol |
UidAc |
4-Hydroxypropranolol Glucuronide beta-glucuronidase |
4-Hydroxypropanolol_glc[c] + h2o[c] -> 4-Hydroxypropanolol[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00571 |
4-Hydroxypropanolol_Glc |
4-Hydroxypropanolol |
UidAe |
4-Hydroxypropranolol Glucuronide beta-glucuronidase extracellular |
4-Hydroxypropanolol_glc[e] + h2o[e] -> 4-Hydroxypropanolol[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00571 |
4-Hydroxypropanolol_Glc |
4-Hydroxypropanolol |
UidAe |
4-Hydroxypropranolol Glucuronide beta-glucuronidase extracellular, periplasmatic |
4-Hydroxypropanolol_glc[p] + h2o[p] -> 4-Hydroxypropanolol[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00571 |
4-Hydroxypropanolol_Glc |
4-Hydroxypropanolol_Glc |
UidABC |
Predicted glucuronide ABC transporter 4-Hydroxypropranolol Glucuronide |
atp[c] + 4-Hydroxypropanolol_glc[e] + h2o[c] -> adp[c] + 4-Hydroxypropanolol_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00571 |
4-Hydroxypropanolol_Glc |
4-Hydroxypropanolol_Glc |
UidP |
Transport of D-Glucuronate 4-Hydroxypropranolol Glucuronide |
4-Hydroxypropanolol_glc[e] -> 4-Hydroxypropanolol_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00571 |
4-Hydroxypropanolol_Glc |
4-Hydroxypropanolol_Glc |
UidB |
Glucuronate transport in via proton symport 4-Hydroxypropranolol Glucuronide |
4-Hydroxypropanolol_glc[e] + h[e] -> 4-Hydroxypropanolol_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00571 |
4-Hydroxypropanolol_Glc |
4-Hydroxypropanolol_Glc |
UidB |
Glucuronate transport in via proton symport 4-Hydroxypropranolol Glucuronide, periplasmatic |
4-Hydroxypropanolol_glc[p] + h[p] -> 4-Hydroxypropanolol_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00571 |
4-Hydroxypropanolol_Glc |
4-Hydroxypropanolol_Glc |
n.a. |
4-Hydroxypropranolol Glucuronide diffusion extracellular to periplasm |
4-Hydroxypropanolol_glc[e] <=> 4-Hydroxypropanolol_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00571 |
4-Hydroxypropanolol |
4-Hydroxypropanolol |
n.a. |
beta-glucuronidase reaction product export 4-Hydroxypropanolol |
4-Hydroxypropanolol[c] -> 4-Hydroxypropanolol[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00571 |
4-Hydroxypropanolol |
4-Hydroxypropanolol |
n.a. |
beta-glucuronidase reaction product export 4-Hydroxypropanolol, periplasmatic |
4-Hydroxypropanolol[c] -> 4-Hydroxypropanolol[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00571 |
4-Hydroxypropanolol |
4-Hydroxypropanolol |
n.a. |
4-Hydroxypropanolol diffusion extracellular to periplasm |
4-Hydroxypropanolol[e] <=> 4-Hydroxypropanolol[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00897 |
4-Hydroxytriazolam_Glc |
4-Hydroxytriazolam |
UidAc |
4-Hydroxy Triazolam Glucuronide beta-glucuronidase |
4-Hydroxytriazolam_glc[c] + h2o[c] -> 4-Hydroxytriazolam[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00897 |
4-Hydroxytriazolam_Glc |
4-Hydroxytriazolam |
UidAe |
4-Hydroxy Triazolam Glucuronide beta-glucuronidase extracellular |
4-Hydroxytriazolam_glc[e] + h2o[e] -> 4-Hydroxytriazolam[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00897 |
4-Hydroxytriazolam_Glc |
4-Hydroxytriazolam |
UidAe |
4-Hydroxy Triazolam Glucuronide beta-glucuronidase extracellular, periplasmatic |
4-Hydroxytriazolam_glc[p] + h2o[p] -> 4-Hydroxytriazolam[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00897 |
4-Hydroxytriazolam_Glc |
4-Hydroxytriazolam_Glc |
UidABC |
Predicted glucuronide ABC transporter 4-Hydroxy Triazolam Glucuronide |
atp[c] + 4-Hydroxytriazolam_glc[e] + h2o[c] -> adp[c] + 4-Hydroxytriazolam_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00897 |
4-Hydroxytriazolam_Glc |
4-Hydroxytriazolam_Glc |
UidP |
Transport of D-Glucuronate 4-Hydroxy Triazolam Glucuronide |
4-Hydroxytriazolam_glc[e] -> 4-Hydroxytriazolam_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00897 |
4-Hydroxytriazolam_Glc |
4-Hydroxytriazolam_Glc |
UidB |
Glucuronate transport in via proton symport 4-Hydroxy Triazolam Glucuronide |
4-Hydroxytriazolam_glc[e] + h[e] -> 4-Hydroxytriazolam_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00897 |
4-Hydroxytriazolam_Glc |
4-Hydroxytriazolam_Glc |
UidB |
Glucuronate transport in via proton symport 4-Hydroxy Triazolam Glucuronide, periplasmatic |
4-Hydroxytriazolam_glc[p] + h[p] -> 4-Hydroxytriazolam_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00897 |
4-Hydroxytriazolam_Glc |
4-Hydroxytriazolam_Glc |
n.a. |
4-Hydroxy Triazolam Glucuronide diffusion extracellular to periplasm |
4-Hydroxytriazolam_glc[e] <=> 4-Hydroxytriazolam_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00897 |
4-Hydroxytriazolam |
4-Hydroxytriazolam |
n.a. |
beta-glucuronidase reaction product export 4-Hydroxytriazolam |
4-Hydroxytriazolam[c] -> 4-Hydroxytriazolam[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00897 |
4-Hydroxytriazolam |
4-Hydroxytriazolam |
n.a. |
beta-glucuronidase reaction product export 4-Hydroxytriazolam, periplasmatic |
4-Hydroxytriazolam[c] -> 4-Hydroxytriazolam[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00897 |
4-Hydroxytriazolam |
4-Hydroxytriazolam |
n.a. |
4-Hydroxytriazolam diffusion extracellular to periplasm |
4-Hydroxytriazolam[e] <=> 4-Hydroxytriazolam[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00582 |
4-Hydroxyvoriconazole_Glc |
4-Hydroxyvoriconazole |
UidAc |
4-Hydroxyvoriconazole Glucuronide beta-glucuronidase |
4-Hydroxyvoriconazole_glc[c] + h2o[c] -> 4-Hydroxyvoriconazole[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00582 |
4-Hydroxyvoriconazole_Glc |
4-Hydroxyvoriconazole |
UidAe |
4-Hydroxyvoriconazole Glucuronide beta-glucuronidase extracellular |
4-Hydroxyvoriconazole_glc[e] + h2o[e] -> 4-Hydroxyvoriconazole[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00582 |
4-Hydroxyvoriconazole_Glc |
4-Hydroxyvoriconazole |
UidAe |
4-Hydroxyvoriconazole Glucuronide beta-glucuronidase extracellular, periplasmatic |
4-Hydroxyvoriconazole_glc[p] + h2o[p] -> 4-Hydroxyvoriconazole[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00582 |
4-Hydroxyvoriconazole_Glc |
4-Hydroxyvoriconazole_Glc |
UidABC |
Predicted glucuronide ABC transporter 4-Hydroxyvoriconazole Glucuronide |
atp[c] + 4-Hydroxyvoriconazole_glc[e] + h2o[c] -> adp[c] + 4-Hydroxyvoriconazole_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00582 |
4-Hydroxyvoriconazole_Glc |
4-Hydroxyvoriconazole_Glc |
UidP |
Transport of D-Glucuronate 4-Hydroxyvoriconazole Glucuronide |
4-Hydroxyvoriconazole_glc[e] -> 4-Hydroxyvoriconazole_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00582 |
4-Hydroxyvoriconazole_Glc |
4-Hydroxyvoriconazole_Glc |
UidB |
Glucuronate transport in via proton symport 4-Hydroxyvoriconazole Glucuronide |
4-Hydroxyvoriconazole_glc[e] + h[e] -> 4-Hydroxyvoriconazole_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00582 |
4-Hydroxyvoriconazole_Glc |
4-Hydroxyvoriconazole_Glc |
UidB |
Glucuronate transport in via proton symport 4-Hydroxyvoriconazole Glucuronide, periplasmatic |
4-Hydroxyvoriconazole_glc[p] + h[p] -> 4-Hydroxyvoriconazole_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00582 |
4-Hydroxyvoriconazole_Glc |
4-Hydroxyvoriconazole_Glc |
n.a. |
4-Hydroxyvoriconazole Glucuronide diffusion extracellular to periplasm |
4-Hydroxyvoriconazole_glc[e] <=> 4-Hydroxyvoriconazole_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00582 |
4-Hydroxyvoriconazole |
4-Hydroxyvoriconazole |
n.a. |
beta-glucuronidase reaction product export 4-Hydroxyvoriconazole |
4-Hydroxyvoriconazole[c] -> 4-Hydroxyvoriconazole[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00582 |
4-Hydroxyvoriconazole |
4-Hydroxyvoriconazole |
n.a. |
beta-glucuronidase reaction product export 4-Hydroxyvoriconazole, periplasmatic |
4-Hydroxyvoriconazole[c] -> 4-Hydroxyvoriconazole[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00582 |
4-Hydroxyvoriconazole |
4-Hydroxyvoriconazole |
n.a. |
4-Hydroxyvoriconazole diffusion extracellular to periplasm |
4-Hydroxyvoriconazole[e] <=> 4-Hydroxyvoriconazole[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
4-Oh-Midazolam |
4-Oh-Midazolam |
n.a. |
beta-glucuronidase reaction product export 4-OH-midazolam |
4-OH-midazolam[c] -> 4-OH-midazolam[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
4-Oh-Midazolam |
4-Oh-Midazolam |
n.a. |
beta-glucuronidase reaction product export 4-OH-midazolam, periplasmatic |
4-OH-midazolam[c] -> 4-OH-midazolam[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
4-Oh-Midazolam |
4-Oh-Midazolam |
n.a. |
4-OH-midazolam diffusion extracellular to periplasm |
4-OH-midazolam[e] <=> 4-OH-midazolam[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB03419 |
Dh5-Fluorouracil |
5-Fluorouracil |
Dpd2 |
Dihydrouracil Dehydrogenase (NADP) (5,6-dihydro-fluorouracil) |
dh5-Fluorouracil[c] + nadp[c] <=> h[c] + nadph[c] + 5-Fluorouracil[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB03419 |
Dh5-Fluorouracil |
5-Fluorouracil |
eDpd |
Dihydrouracil Dehydrogenase (NADP) (5,6-dihydro-fluorouracil) |
dh5-Fluorouracil[e] + nadp[e] <=> h[e] + nadph[e] + 5-Fluorouracil[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB03419 |
Dh5-Fluorouracil |
5-Fluorouracil |
eDpd |
Dihydrouracil Dehydrogenase (NADP) (5,6-dihydro-fluorouracil), periplasmatic |
nadp[c] + dh5-Fluorouracil[p] <=> nadph[c] + 5-Fluorouracil[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00233 |
5-Aminosalicylic Acid (Mesalamine) |
5-Aminosalicylic Acid (Mesalamine) |
NatABC |
5-aminosalicylic acid ABC transporter |
atp[c] + 5-Aminosalicylic Acid (Mesalamine)[e] + h2o[c] -> adp[c] + 5-Aminosalicylic Acid (Mesalamine)[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00233 |
5-Aminosalicylic Acid (Mesalamine) |
5-Aminosalicylic Acid (Mesalamine) |
AzorDMT |
5-Aminosalicylic Acid (Mesalamine) transport via proton symport |
5-Aminosalicylic Acid (Mesalamine)[e] + h[e] <=> 5-Aminosalicylic Acid (Mesalamine)[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB03419 |
5-Fluorouracil |
Dh5-Fluorouracil |
Dpd1 |
5, 6-Dihydrouracil:NAD+ Oxidoreductase (5-fluorouracil) |
5-Fluorouracil[c] + nadh[c] + h[c] -> nad[c] + dh5-Fluorouracil[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 12352929 |
| DB03419 |
5-Fluorouracil |
5-Fluorouracil |
CodB |
5-Fluorouracil Transport via Faciliated Diffusion |
5-Fluorouracil[e] <=> 5-Fluorouracil[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB03419 |
5-Fluorouracil |
5-Fluorouracil |
n.a. |
5-Fluorouracil diffusion extracellular to periplasm |
5-Fluorouracil[e] <=> 5-Fluorouracil[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB03419 |
5-Fluorouracil |
5-Fluorouracil |
CodB |
5-Fluorouracil transport via Faciliated Diffusion, periplasmatic |
5-Fluorouracil[p] <=> 5-Fluorouracil[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00891 |
5-Hydroxy-Sulfapyridine_Glc |
5-Hydroxy-Sulfapyridine |
UidAc |
5-Hydroxy-Sulfapyridine-O-Glucuronide beta-glucuronidase |
5-Hydroxy-Sulfapyridine_glc[c] + h2o[c] -> 5-Hydroxy-Sulfapyridine[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00891 |
5-Hydroxy-Sulfapyridine_Glc |
5-Hydroxy-Sulfapyridine |
UidAe |
5-Hydroxy-Sulfapyridine-O-Glucuronide beta-glucuronidase extracellular |
5-Hydroxy-Sulfapyridine_glc[e] + h2o[e] -> 5-Hydroxy-Sulfapyridine[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00891 |
5-Hydroxy-Sulfapyridine_Glc |
5-Hydroxy-Sulfapyridine |
UidAe |
5-Hydroxy-Sulfapyridine-O-Glucuronide beta-glucuronidase extracellular, periplasmatic |
5-Hydroxy-Sulfapyridine_glc[p] + h2o[p] -> 5-Hydroxy-Sulfapyridine[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00891 |
5-Hydroxy-Sulfapyridine_Glc |
5-Hydroxy-Sulfapyridine_Glc |
UidABC |
Predicted glucuronide ABC transporter 5-Hydroxy-Sulfapyridine-O-Glucuronide |
atp[c] + 5-Hydroxy-Sulfapyridine_glc[e] + h2o[c] -> adp[c] + 5-Hydroxy-Sulfapyridine_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00891 |
5-Hydroxy-Sulfapyridine_Glc |
5-Hydroxy-Sulfapyridine_Glc |
UidP |
Transport of D-Glucuronate 5-Hydroxy-Sulfapyridine-O-Glucuronide |
5-Hydroxy-Sulfapyridine_glc[e] -> 5-Hydroxy-Sulfapyridine_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00891 |
5-Hydroxy-Sulfapyridine_Glc |
5-Hydroxy-Sulfapyridine_Glc |
UidB |
Glucuronate transport in via proton symport 5-Hydroxy-Sulfapyridine-O-Glucuronide |
5-Hydroxy-Sulfapyridine_glc[e] + h[e] -> 5-Hydroxy-Sulfapyridine_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00891 |
5-Hydroxy-Sulfapyridine_Glc |
5-Hydroxy-Sulfapyridine_Glc |
UidB |
Glucuronate transport in via proton symport 5-Hydroxy-Sulfapyridine-O-Glucuronide, periplasmatic |
5-Hydroxy-Sulfapyridine_glc[p] + h[p] -> 5-Hydroxy-Sulfapyridine_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00891 |
5-Hydroxy-Sulfapyridine_Glc |
5-Hydroxy-Sulfapyridine_Glc |
n.a. |
5-Hydroxy-Sulfapyridine-O-Glucuronide diffusion extracellular to periplasm |
5-Hydroxy-Sulfapyridine_glc[e] <=> 5-Hydroxy-Sulfapyridine_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00891 |
5-Hydroxy-Sulfapyridine |
5-Hydroxy-Sulfapyridine |
n.a. |
beta-glucuronidase reaction product export 5-Hydroxy-Sulfapyridine |
5-Hydroxy-Sulfapyridine[c] -> 5-Hydroxy-Sulfapyridine[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00891 |
5-Hydroxy-Sulfapyridine |
5-Hydroxy-Sulfapyridine |
n.a. |
beta-glucuronidase reaction product export 5-Hydroxy-Sulfapyridine, periplasmatic |
5-Hydroxy-Sulfapyridine[c] -> 5-Hydroxy-Sulfapyridine[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00891 |
5-Hydroxy-Sulfapyridine |
5-Hydroxy-Sulfapyridine |
n.a. |
5-Hydroxy-Sulfapyridine diffusion extracellular to periplasm |
5-Hydroxy-Sulfapyridine[e] <=> 5-Hydroxy-Sulfapyridine[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
5-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu |
5-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
UidAc |
5-hydroxy-fluvastatin-glucuronide beta-glucuronidase |
5-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu[c] + h2o[c] -> 5-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01095 |
5-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu |
5-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
UidAe |
5-hydroxy-fluvastatin-glucuronide beta-glucuronidase extracellular |
5-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu[e] + h2o[e] -> 5-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01095 |
5-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu |
5-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
UidAe |
5-hydroxy-fluvastatin-glucuronide beta-glucuronidase extracellular, periplasmatic |
5-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu[p] + h2o[p] -> 5-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01095 |
5-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu |
5-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu |
UidABC |
Predicted glucuronide ABC transporter 5-hydroxy-fluvastatin-glucuronide |
atp[c] + 5-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu[e] + h2o[c] -> adp[c] + 5-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
5-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu |
5-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu |
UidP |
Transport of D-Glucuronate 5-hydroxy-fluvastatin-glucuronide |
5-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu[e] -> 5-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
5-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu |
5-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu |
UidB |
Glucuronate transport in via proton symport 5-hydroxy-fluvastatin-glucuronide |
5-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu[e] + h[e] -> 5-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
5-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu |
5-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu |
UidB |
Glucuronate transport in via proton symport 5-hydroxy-fluvastatin-glucuronide, periplasmatic |
5-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu[p] + h[p] -> 5-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
5-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu |
5-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu |
n.a. |
5-hydroxy-fluvastatin-glucuronide diffusion extracellular to periplasm |
5-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu[e] <=> 5-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
5-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
5-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
n.a. |
beta-glucuronidase reaction product export 5-hydroxy-fluvastatin |
5-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[c] -> 5-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
5-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
5-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
n.a. |
beta-glucuronidase reaction product export 5-hydroxy-fluvastatin, periplasmatic |
5-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[c] -> 5-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
5-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
5-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
n.a. |
5-hydroxy-fluvastatin diffusion extracellular to periplasm |
5-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[e] <=> 5-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01120 |
6-Beta-Oh-Gliclazideglc |
6-Beta-Oh-Gliclazide |
UidAc |
6-beta-OH-gliclazide-glucuronide beta-glucuronidase |
6-beta-OH-gliclazideglc[c] + h2o[c] -> 6-beta-OH-gliclazide[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01120 |
6-Beta-Oh-Gliclazideglc |
6-Beta-Oh-Gliclazide |
UidAe |
6-beta-OH-gliclazide-glucuronide beta-glucuronidase extracellular |
6-beta-OH-gliclazideglc[e] + h2o[e] -> 6-beta-OH-gliclazide[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01120 |
6-Beta-Oh-Gliclazideglc |
6-Beta-Oh-Gliclazide |
UidAe |
6-beta-OH-gliclazide-glucuronide beta-glucuronidase extracellular, periplasmatic |
6-beta-OH-gliclazideglc[p] + h2o[p] -> 6-beta-OH-gliclazide[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01120 |
6-Beta-Oh-Gliclazideglc |
6-Beta-Oh-Gliclazideglc |
UidABC |
Predicted glucuronide ABC transporter 6-beta-OH-gliclazide-glucuronide |
atp[c] + 6-beta-OH-gliclazideglc[e] + h2o[c] -> adp[c] + 6-beta-OH-gliclazideglc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01120 |
6-Beta-Oh-Gliclazideglc |
6-Beta-Oh-Gliclazideglc |
UidP |
Transport of D-Glucuronate 6-beta-OH-gliclazide-glucuronide |
6-beta-OH-gliclazideglc[e] -> 6-beta-OH-gliclazideglc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01120 |
6-Beta-Oh-Gliclazideglc |
6-Beta-Oh-Gliclazideglc |
UidB |
Glucuronate transport in via proton symport 6-beta-OH-gliclazide-glucuronide |
6-beta-OH-gliclazideglc[e] + h[e] -> 6-beta-OH-gliclazideglc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01120 |
6-Beta-Oh-Gliclazideglc |
6-Beta-Oh-Gliclazideglc |
UidB |
Glucuronate transport in via proton symport 6-beta-OH-gliclazide-glucuronide, periplasmatic |
6-beta-OH-gliclazideglc[p] + h[p] -> 6-beta-OH-gliclazideglc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01120 |
6-Beta-Oh-Gliclazideglc |
6-Beta-Oh-Gliclazideglc |
n.a. |
6-beta-OH-gliclazide-glucuronide diffusion extracellular to periplasm |
6-beta-OH-gliclazideglc[e] <=> 6-beta-OH-gliclazideglc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01120 |
6-Beta-Oh-Gliclazide |
6-Beta-Oh-Gliclazide |
n.a. |
beta-glucuronidase reaction product export 6-beta-OH-gliclazide |
6-beta-OH-gliclazide[c] -> 6-beta-OH-gliclazide[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01120 |
6-Beta-Oh-Gliclazide |
6-Beta-Oh-Gliclazide |
n.a. |
beta-glucuronidase reaction product export 6-beta-OH-gliclazide, periplasmatic |
6-beta-OH-gliclazide[c] -> 6-beta-OH-gliclazide[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01120 |
6-Beta-Oh-Gliclazide |
6-Beta-Oh-Gliclazide |
n.a. |
6-beta-OH-gliclazide diffusion extracellular to periplasm |
6-beta-OH-gliclazide[e] <=> 6-beta-OH-gliclazide[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
6-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu |
6-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
UidAc |
6-hydroxy-fluvastatin-glucuronide beta-glucuronidase |
6-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu[c] + h2o[c] -> 6-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01095 |
6-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu |
6-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
UidAe |
6-hydroxy-fluvastatin-glucuronide beta-glucuronidase extracellular |
6-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu[e] + h2o[e] -> 6-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01095 |
6-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu |
6-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
UidAe |
6-hydroxy-fluvastatin-glucuronide beta-glucuronidase extracellular, periplasmatic |
6-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu[p] + h2o[p] -> 6-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01095 |
6-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu |
6-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu |
UidABC |
Predicted glucuronide ABC transporter 6-hydroxy-fluvastatin-glucuronide |
atp[c] + 6-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu[e] + h2o[c] -> adp[c] + 6-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
6-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu |
6-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu |
UidP |
Transport of D-Glucuronate 6-hydroxy-fluvastatin-glucuronide |
6-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu[e] -> 6-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
6-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu |
6-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu |
UidB |
Glucuronate transport in via proton symport 6-hydroxy-fluvastatin-glucuronide |
6-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu[e] + h[e] -> 6-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
6-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu |
6-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu |
UidB |
Glucuronate transport in via proton symport 6-hydroxy-fluvastatin-glucuronide, periplasmatic |
6-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu[p] + h[p] -> 6-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
6-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu |
6-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu |
n.a. |
6-hydroxy-fluvastatin-glucuronide diffusion extracellular to periplasm |
6-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu[e] <=> 6-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
6-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
6-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
n.a. |
beta-glucuronidase reaction product export 6-hydroxy-fluvastatin |
6-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[c] -> 6-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
6-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
6-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
n.a. |
beta-glucuronidase reaction product export 6-hydroxy-fluvastatin, periplasmatic |
6-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[c] -> 6-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
6-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
6-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
n.a. |
6-hydroxy-fluvastatin diffusion extracellular to periplasm |
6-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[e] <=> 6-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01120 |
7-Beta-Oh-Gliclazideglc |
7-Beta-Oh-Gliclazide |
UidAc |
7-beta-OH-gliclazide beta-glucuronidase |
7-beta-OH-gliclazideglc[c] + h2o[c] -> 7-beta-OH-gliclazide[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01120 |
7-Beta-Oh-Gliclazideglc |
7-Beta-Oh-Gliclazide |
UidAe |
7-beta-OH-gliclazide beta-glucuronidase extracellular |
7-beta-OH-gliclazideglc[e] + h2o[e] -> 7-beta-OH-gliclazide[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01120 |
7-Beta-Oh-Gliclazideglc |
7-Beta-Oh-Gliclazide |
UidAe |
7-beta-OH-gliclazide beta-glucuronidase extracellular, periplasmatic |
7-beta-OH-gliclazideglc[p] + h2o[p] -> 7-beta-OH-gliclazide[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01120 |
7-Beta-Oh-Gliclazide |
7-Beta-Oh-Gliclazide |
UidABC |
Predicted glucuronide ABC transporter 7-beta-OH-gliclazide |
atp[c] + 7-beta-OH-gliclazide[e] + h2o[c] -> adp[c] + 7-beta-OH-gliclazide[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01120 |
7-Beta-Oh-Gliclazideglc |
7-Beta-Oh-Gliclazideglc |
n.a. |
Glucuronate transport in via proton symport (in),7-beta-OH-gliclazide-glucuronide, periplasmatic |
7-beta-OH-gliclazideglc[p] + h[p] -> 7-beta-OH-gliclazideglc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01120 |
7-Beta-Oh-Gliclazideglc |
7-Beta-Oh-Gliclazideglc |
n.a. |
beta-glucuronidase reaction product export 7-beta-OH-gliclazide-glucuronide |
7-beta-OH-gliclazideglc[c] -> 7-beta-OH-gliclazideglc[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01120 |
7-Beta-Oh-Gliclazideglc |
7-Beta-Oh-Gliclazideglc |
n.a. |
7-beta-OH-gliclazide-glucuronide diffusion extracellular to periplasm |
7-beta-OH-gliclazideglc[e] <=> 7-beta-OH-gliclazideglc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01120 |
7-Beta-Oh-Gliclazide |
7-Beta-Oh-Gliclazide |
UidP |
Transport of D-Glucuronate 7-beta-OH-gliclazide |
7-beta-OH-gliclazide[e] -> 7-beta-OH-gliclazide[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01120 |
7-Beta-Oh-Gliclazide |
7-Beta-Oh-Gliclazide |
UidB |
Glucuronate transport in via proton symport 7-beta-OH-gliclazide |
7-beta-OH-gliclazide[e] + h[e] -> 7-beta-OH-gliclazide[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01120 |
7-Beta-Oh-Gliclazide |
7-Beta-Oh-Gliclazide |
n.a. |
beta-glucuronidase reaction product export,7-beta-OH-gliclazide, periplasmatic |
7-beta-OH-gliclazide[c] -> 7-beta-OH-gliclazide[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01120 |
7-Beta-Oh-Gliclazide |
7-Beta-Oh-Gliclazide |
n.a. |
7-beta-OH-gliclazide diffusion extracellular to periplasm |
7-beta-OH-gliclazide[e] <=> 7-beta-OH-gliclazide[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
7-Hydroxy-Efavirenz_Glc |
7-Hydroxy-Efavirenz |
UidAc |
7-hydroxy-Efavirenz Glucuronide beta-glucuronidase |
7-hydroxy-Efavirenz_glc[c] + h2o[c] -> 7-hydroxy-Efavirenz[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00625 |
7-Hydroxy-Efavirenz_Glc |
7-Hydroxy-Efavirenz |
UidAe |
7-hydroxy-Efavirenz Glucuronide beta-glucuronidase extracellular |
7-hydroxy-Efavirenz_glc[e] + h2o[e] -> 7-hydroxy-Efavirenz[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00625 |
7-Hydroxy-Efavirenz_Glc |
7-Hydroxy-Efavirenz |
UidAe |
7-hydroxy-Efavirenz Glucuronide beta-glucuronidase extracellular, periplasmatic |
7-hydroxy-Efavirenz_glc[p] + h2o[p] -> 7-hydroxy-Efavirenz[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00625 |
7-Hydroxy-Efavirenz_Glc |
7-Hydroxy-Efavirenz_Glc |
UidABC |
Predicted glucuronide ABC transporter 7-hydroxy-Efavirenz Glucuronide |
atp[c] + 7-hydroxy-Efavirenz_glc[e] + h2o[c] -> adp[c] + 7-hydroxy-Efavirenz_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
7-Hydroxy-Efavirenz_Glc |
7-Hydroxy-Efavirenz_Glc |
UidP |
Transport of D-Glucuronate 7-hydroxy-Efavirenz Glucuronide |
7-hydroxy-Efavirenz_glc[e] -> 7-hydroxy-Efavirenz_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
7-Hydroxy-Efavirenz_Glc |
7-Hydroxy-Efavirenz_Glc |
UidB |
Glucuronate transport in via proton symport 7-hydroxy-Efavirenz Glucuronide |
7-hydroxy-Efavirenz_glc[e] + h[e] -> 7-hydroxy-Efavirenz_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
7-Hydroxy-Efavirenz_Glc |
7-Hydroxy-Efavirenz_Glc |
UidB |
Glucuronate transport in via proton symport 7-hydroxy-Efavirenz Glucuronide, periplasmatic |
7-hydroxy-Efavirenz_glc[p] + h[p] -> 7-hydroxy-Efavirenz_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
7-Hydroxy-Efavirenz_Glc |
7-Hydroxy-Efavirenz_Glc |
n.a. |
7-hydroxy-Efavirenz Glucuronide diffusion extracellular to periplasm |
7-hydroxy-Efavirenz_glc[e] <=> 7-hydroxy-Efavirenz_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
7-Hydroxy-Efavirenz |
7-Hydroxy-Efavirenz |
n.a. |
beta-glucuronidase reaction product export 7-hydroxy-Efavirenz |
7-hydroxy-Efavirenz[c] -> 7-hydroxy-Efavirenz[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
7-Hydroxy-Efavirenz |
7-Hydroxy-Efavirenz |
n.a. |
beta-glucuronidase reaction product export 7-hydroxy-Efavirenz, periplasmatic |
7-hydroxy-Efavirenz[c] -> 7-hydroxy-Efavirenz[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
7-Hydroxy-Efavirenz |
7-Hydroxy-Efavirenz |
n.a. |
7-hydroxy-Efavirenz diffusion extracellular to periplasm |
7-hydroxy-Efavirenz[e] <=> 7-hydroxy-Efavirenz[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
8,14-Dihydroxyefavirenz_Glc |
8,14-Dihydroxyefavirenz |
UidAc |
8 14-Dihydroxyefavirenz Glucuronide beta-glucuronidase |
8,14-Dihydroxyefavirenz_glc[c] + h2o[c] -> 8,14-Dihydroxyefavirenz[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00625 |
8,14-Dihydroxyefavirenz_Glc |
8,14-Dihydroxyefavirenz |
UidAe |
8 14-Dihydroxyefavirenz Glucuronide beta-glucuronidase extracellular |
8,14-Dihydroxyefavirenz_glc[e] + h2o[e] -> 8,14-Dihydroxyefavirenz[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00625 |
8,14-Dihydroxyefavirenz_Glc |
8,14-Dihydroxyefavirenz |
UidAe |
8 14-Dihydroxyefavirenz Glucuronide beta-glucuronidase extracellular, periplasmatic |
8,14-Dihydroxyefavirenz_glc[p] + h2o[p] -> 8,14-Dihydroxyefavirenz[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00625 |
8,14-Dihydroxyefavirenz_Glc |
8,14-Dihydroxyefavirenz_Glc |
UidABC |
Predicted glucuronide ABC transporter 8,14-Dihydroxyefavirenz Glucuronide |
atp[c] + 8,14-Dihydroxyefavirenz_glc[e] + h2o[c] -> adp[c] + 8,14-Dihydroxyefavirenz_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
8,14-Dihydroxyefavirenz_Glc |
8,14-Dihydroxyefavirenz_Glc |
UidP |
Transport of D-Glucuronate 8 14-Dihydroxyefavirenz Glucuronide |
8,14-Dihydroxyefavirenz_glc[e] -> 8,14-Dihydroxyefavirenz_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
8,14-Dihydroxyefavirenz_Glc |
8,14-Dihydroxyefavirenz_Glc |
UidB |
Glucuronate transport in via proton symport 8 14-Dihydroxyefavirenz Glucuronide |
8,14-Dihydroxyefavirenz_glc[e] + h[e] -> 8,14-Dihydroxyefavirenz_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
8,14-Dihydroxyefavirenz_Glc |
8,14-Dihydroxyefavirenz_Glc |
UidB |
Glucuronate transport in via proton symport 8 14-Dihydroxyefavirenz Glucuronide, periplasmatic |
8,14-Dihydroxyefavirenz_glc[p] + h[p] -> 8,14-Dihydroxyefavirenz_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
8,14-Dihydroxyefavirenz_Glc |
8,14-Dihydroxyefavirenz_Glc |
n.a. |
8,14-Dihydroxyefavirenz Glucuronide diffusion extracellular to periplasm |
8,14-Dihydroxyefavirenz_glc[e] <=> 8,14-Dihydroxyefavirenz_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
8,14-Dihydroxyefavirenz |
8,14-Dihydroxyefavirenz |
n.a. |
beta-glucuronidase reaction product export 8 14-Dihydroxyefavirenz |
8,14-Dihydroxyefavirenz[c] -> 8,14-Dihydroxyefavirenz[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
8,14-Dihydroxyefavirenz |
8,14-Dihydroxyefavirenz |
n.a. |
beta-glucuronidase reaction product export 8 14-Dihydroxyefavirenz, periplasmatic |
8,14-Dihydroxyefavirenz[c] -> 8,14-Dihydroxyefavirenz[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
8,14-Dihydroxyefavirenz |
8,14-Dihydroxyefavirenz |
n.a. |
8,14-Dihydroxyefavirenz diffusion extracellular to periplasm |
8,14-Dihydroxyefavirenz[e] <=> 8,14-Dihydroxyefavirenz[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
8-Hydroxy-Efavirenz_Glc |
8-Hydroxy-Efavirenz |
UidAc |
8-hydroxy-Efavirenz Glucuronide beta-glucuronidase |
8-hydroxy-Efavirenz_glc[c] + h2o[c] -> 8-hydroxy-Efavirenz[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00625 |
8-Hydroxy-Efavirenz_Glc |
8-Hydroxy-Efavirenz |
UidAe |
8-hydroxy-Efavirenz Glucuronide beta-glucuronidase extracellular |
8-hydroxy-Efavirenz_glc[e] + h2o[e] -> 8-hydroxy-Efavirenz[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00625 |
8-Hydroxy-Efavirenz_Glc |
8-Hydroxy-Efavirenz |
UidAe |
8-hydroxy-Efavirenz Glucuronide beta-glucuronidase extracellular, periplasmatic |
8-hydroxy-Efavirenz_glc[p] + h2o[p] -> 8-hydroxy-Efavirenz[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00625 |
8-Hydroxy-Efavirenz_Glc |
8-Hydroxy-Efavirenz_Glc |
UidABC |
Predicted glucuronide ABC transporter 8-hydroxy-Efavirenz Glucuronide |
atp[c] + 8-hydroxy-Efavirenz_glc[e] + h2o[c] -> adp[c] + 8-hydroxy-Efavirenz_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
8-Hydroxy-Efavirenz_Glc |
8-Hydroxy-Efavirenz_Glc |
UidP |
Transport of D-Glucuronate 8-hydroxy-Efavirenz Glucuronide |
8-hydroxy-Efavirenz_glc[e] -> 8-hydroxy-Efavirenz_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
8-Hydroxy-Efavirenz_Glc |
8-Hydroxy-Efavirenz_Glc |
UidB |
Glucuronate transport in via proton symport 8-hydroxy-Efavirenz Glucuronide |
8-hydroxy-Efavirenz_glc[e] + h[e] -> 8-hydroxy-Efavirenz_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
8-Hydroxy-Efavirenz_Glc |
8-Hydroxy-Efavirenz_Glc |
UidB |
Glucuronate transport in via proton symport 8-hydroxy-Efavirenz Glucuronide, periplasmatic |
8-hydroxy-Efavirenz_glc[p] + h[p] -> 8-hydroxy-Efavirenz_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
8-Hydroxy-Efavirenz_Glc |
8-Hydroxy-Efavirenz_Glc |
n.a. |
8-hydroxy-Efavirenz Glucuronide diffusion extracellular to periplasm |
8-hydroxy-Efavirenz_glc[e] <=> 8-hydroxy-Efavirenz_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
8-Hydroxy-Efavirenz |
8-Hydroxy-Efavirenz |
n.a. |
beta-glucuronidase reaction product export 8-hydroxy-Efavirenz |
8-hydroxy-Efavirenz[c] -> 8-hydroxy-Efavirenz[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
8-Hydroxy-Efavirenz |
8-Hydroxy-Efavirenz |
n.a. |
beta-glucuronidase reaction product export 8-hydroxy-Efavirenz, periplasmatic |
8-hydroxy-Efavirenz[c] -> 8-hydroxy-Efavirenz[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
8-Hydroxy-Efavirenz |
8-Hydroxy-Efavirenz |
n.a. |
8-hydroxy-Efavirenz diffusion extracellular to periplasm |
8-hydroxy-Efavirenz[e] <=> 8-hydroxy-Efavirenz[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00160 |
4-Aminobenzoyl-Beta-Alanine |
4-Aminobenzoyl-Beta-Alanine |
AzorDMT |
4-Aminobenzoyl-Beta-Alanine transport via proton symport |
4-Aminobenzoyl-Beta-Alanine[e] + h[e] <=> 4-Aminobenzoyl-Beta-Alanine[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00160 |
4-Aminobenzoyl-Beta-Alanine |
4-Aminobenzoyl-Beta-Alanine |
AzorDMT |
4-Aminobenzoyl-Beta-Alanine transport via proton symport, periplasmatic |
4-Aminobenzoyl-Beta-Alanine[p] + h[p] <=> 4-Aminobenzoyl-Beta-Alanine[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00160 |
4-Aminobenzoyl-Beta-Alanine |
4-Aminobenzoyl-Beta-Alanine |
n.a. |
4-Aminobenzoyl-Beta-Alanine diffusion extracellular to periplasm |
4-Aminobenzoyl-Beta-Alanine[e] <=> 4-Aminobenzoyl-Beta-Alanine[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00145 |
Acetyl 4-Aminobenzoylglycinecine_Glc |
Acetyl 4-Aminobenzoylglycinecine |
UidAc |
Acetyl 4-Aminobenzoylglycine Glucuronide beta-glucuronidase |
Acetyl 4-AminobenzoylGlycinecine_glc[c] + h2o[c] -> Acetyl 4-AminobenzoylGlycinecine[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00145 |
Acetyl 4-Aminobenzoylglycinecine_Glc |
Acetyl 4-Aminobenzoylglycinecine |
UidAe |
Acetyl 4-Aminobenzoylglycine Glucuronide beta-glucuronidase extracellular |
Acetyl 4-AminobenzoylGlycinecine_glc[e] + h2o[e] -> Acetyl 4-AminobenzoylGlycinecine[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00145 |
Acetyl 4-Aminobenzoylglycinecine_Glc |
Acetyl 4-Aminobenzoylglycinecine |
UidAe |
Acetyl 4-Aminobenzoylglycine Glucuronide beta-glucuronidase extracellular, periplasmatic |
Acetyl 4-AminobenzoylGlycinecine_glc[p] + h2o[p] -> Acetyl 4-AminobenzoylGlycinecine[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00145 |
Acetyl 4-Aminobenzoylglycinecine_Glc |
Acetyl 4-Aminobenzoylglycinecine_Glc |
UidABC |
Predicted glucuronide ABC transporter Acetyl 4-Aminobenzoylglycine Glucuronide |
atp[c] + Acetyl 4-AminobenzoylGlycinecine_glc[e] + h2o[c] -> adp[c] + Acetyl 4-AminobenzoylGlycinecine_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00145 |
Acetyl 4-Aminobenzoylglycinecine_Glc |
Acetyl 4-Aminobenzoylglycinecine_Glc |
UidP |
Transport of D-Glucuronate Acetyl 4-Aminobenzoylglycine Glucuronide |
Acetyl 4-AminobenzoylGlycinecine_glc[e] -> Acetyl 4-AminobenzoylGlycinecine_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00145 |
Acetyl 4-Aminobenzoylglycinecine_Glc |
Acetyl 4-Aminobenzoylglycinecine_Glc |
UidB |
Glucuronate transport in via proton symport Acetyl 4-Aminobenzoylglycine Glucuronide |
Acetyl 4-AminobenzoylGlycinecine_glc[e] + h[e] -> Acetyl 4-AminobenzoylGlycinecine_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00145 |
Acetyl 4-Aminobenzoylglycinecine_Glc |
Acetyl 4-Aminobenzoylglycinecine_Glc |
UidB |
Glucuronate transport in via proton symport Acetyl 4-Aminobenzoylglycine Glucuronide, periplasmatic |
Acetyl 4-AminobenzoylGlycinecine_glc[p] + h[p] -> Acetyl 4-AminobenzoylGlycinecine_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00145 |
Acetyl 4-Aminobenzoylglycinecine_Glc |
Acetyl 4-Aminobenzoylglycinecine_Glc |
n.a. |
Acetyl 4-Aminobenzoylglycine Glucuronide diffusion extracellular to periplasm |
Acetyl 4-AminobenzoylGlycinecine_glc[e] <=> Acetyl 4-AminobenzoylGlycinecine_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00145 |
Acetyl 4-Aminobenzoylglycinecine |
Acetyl 4-Aminobenzoylglycinecine |
n.a. |
beta-glucuronidase reaction product export Acetyl 4-Aminobenzoylglycine |
Acetyl 4-AminobenzoylGlycinecine[c] -> Acetyl 4-AminobenzoylGlycinecine[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00145 |
Acetyl 4-Aminobenzoylglycinecine |
Acetyl 4-Aminobenzoylglycinecine |
n.a. |
beta-glucuronidase reaction product export Acetyl 4-Aminobenzoylglycine, periplasmatic |
Acetyl 4-AminobenzoylGlycinecine[c] -> Acetyl 4-AminobenzoylGlycinecine[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00145 |
Acetyl 4-Aminobenzoylglycinecine |
Acetyl 4-Aminobenzoylglycinecine |
n.a. |
Acetyl 4-Aminobenzoylglycine diffusion extracellular to periplasm |
Acetyl 4-AminobenzoylGlycinecine[e] <=> Acetyl 4-AminobenzoylGlycinecine[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00233 |
Ac5-Aminosalicylic Acid (Mesalamine) |
Ac5-Aminosalicylic Acid (Mesalamine) |
NatABC |
N-Acetyl-5-Aminosalicylic Acid ABC transporter |
atp[c] + ac5-Aminosalicylic Acid (Mesalamine)[c] + h2o[c] -> adp[c] + ac5-Aminosalicylic Acid (Mesalamine)[e] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00233 |
Ac5-Aminosalicylic Acid (Mesalamine) |
Ac5-Aminosalicylic Acid (Mesalamine) |
NatABC |
N-Acetyl-5-Aminosalicylic Acid ABC transporter, periplasmatic |
ac5-Aminosalicylic Acid (Mesalamine)[c] + atp[c] + h2o[c] -> adp[c] + h[c] + pi[c] + ac5-Aminosalicylic Acid (Mesalamine)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00233 |
5-Aminosalicylic Acid (Mesalamine) |
Ac5-Aminosalicylic Acid (Mesalamine) |
NAT |
5-aminosalicylic acid acetylation |
5-Aminosalicylic Acid (Mesalamine)[c] + accoa[c] <=> ac5-Aminosalicylic Acid (Mesalamine)[c] + coa[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 11344150, PMID: 15447630 |
| DB00233 |
5-Aminosalicylic Acid (Mesalamine) |
Ac5-Aminosalicylic Acid (Mesalamine) |
eNAT |
5-aminosalicylic acid acetylation |
5-Aminosalicylic Acid (Mesalamine)[e] + accoa[e] <=> ac5-Aminosalicylic Acid (Mesalamine)[e] + coa[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 11344150, PMID: 15447630 |
| DB00233 |
Ac5-Aminosalicylic Acid (Mesalamine) |
Ac5-Aminosalicylic Acid (Mesalamine) |
n.a. |
N-Acetyl-5-Aminosalicylic Acid permease, periplasmatic |
ac5-Aminosalicylic Acid (Mesalamine)[c] <=> ac5-Aminosalicylic Acid (Mesalamine)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00233 |
Ac5-Aminosalicylic Acid (Mesalamine) |
Ac5-Aminosalicylic Acid (Mesalamine) |
n.a. |
N-Acetyl-5-Aminosalicylic Acid diffusion extracellular to periplasm |
ac5-Aminosalicylic Acid (Mesalamine)[e] <=> ac5-Aminosalicylic Acid (Mesalamine)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00951 |
N-Acetylisoniazid |
N-Acetylisoniazid |
NatABC |
N-Acetylisoniazid ABC transporter |
atp[c] + N-Acetylisoniazid[c] + h2o[c] -> adp[c] + N-Acetylisoniazid[e] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00951 |
N-Acetylisoniazid |
N-Acetylisoniazid |
NatABC |
N-Acetylisoniazid ABC transporter, periplasmatic |
N-Acetylisoniazid[c] + atp[c] + h2o[c] -> adp[c] + h[c] + pi[c] + N-Acetylisoniazid[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00951 |
N-Acetylisoniazid |
N-Acetylisoniazid |
n.a. |
N-Acetylisoniazid permease, periplasmatic |
N-Acetylisoniazid[c] <=> N-Acetylisoniazid[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00951 |
N-Acetylisoniazid |
N-Acetylisoniazid |
n.a. |
N-Acetylisoniazid diffusion extracellular to periplasm |
N-Acetylisoniazid[e] <=> N-Acetylisoniazid[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Acetaminophen_Glc |
Acetaminophen |
UidAc |
Acetaminophen Glucuronide beta-glucuronidase |
Acetaminophen_glc[c] + h2o[c] -> Acetaminophen[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 29212822 |
| DB00316 |
Acetaminophen_Glc |
Acetaminophen |
UidAe |
Acetaminophen Glucuronide beta-glucuronidase extracellular |
Acetaminophen_glc[e] + h2o[e] -> Acetaminophen[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 29212822 |
| DB00316 |
Acetaminophen_Glc |
Acetaminophen |
UidAe |
Acetaminophen Glucuronide beta-glucuronidase extracellular, periplasmatic |
Acetaminophen_glc[p] + h2o[p] -> Acetaminophen[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 29212822 |
| DB00316 |
Acetaminophen_Glc |
Acetaminophen_Glc |
UidABC |
Predicted glucuronide ABC transporter Acetaminophen Glucuronide |
atp[c] + Acetaminophen_glc[e] + h2o[c] -> adp[c] + Acetaminophen_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Acetaminophen_Glc |
Acetaminophen_Glc |
UidP |
Transport of D-Glucuronate Acetaminophen Glucuronide |
Acetaminophen_glc[e] -> Acetaminophen_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Acetaminophen_Glc |
Acetaminophen_Glc |
UidB |
Glucuronate transport in via proton symport Acetaminophen Glucuronide |
Acetaminophen_glc[e] + h[e] -> Acetaminophen_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Acetaminophen_Glc |
Acetaminophen_Glc |
UidB |
Glucuronate transport in via proton symport Acetaminophen Glucuronide, periplasmatic |
Acetaminophen_glc[p] + h[p] -> Acetaminophen_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Acetaminophen_Glc |
Acetaminophen_Glc |
n.a. |
Acetaminophen Glucuronide diffusion extracellular to periplasm |
Acetaminophen_glc[e] <=> Acetaminophen_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Acetaminophenglu |
Acetaminophen |
UidAc |
Acetaminophen glucuronide beta-glucuronidase |
Acetaminophenglu[c] + h2o[c] -> Acetaminophen[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 29212822 |
| DB00316 |
Acetaminophenglu |
Acetaminophen |
UidAe |
Acetaminophen glucuronide beta-glucuronidase extracellular |
Acetaminophenglu[e] + h2o[e] -> Acetaminophen[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 29212822 |
| DB00316 |
Acetaminophenglu |
Acetaminophen |
UidAe |
Acetaminophen glucuronide beta-glucuronidase extracellular, periplasmatic |
Acetaminophenglu[p] + h2o[p] -> Acetaminophen[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 29212822 |
| DB00316 |
Acetaminophenglu |
Acetaminophenglu |
UidABC |
Predicted glucuronide ABC transporter Acetaminophen glucuronide |
atp[c] + Acetaminophenglu[e] + h2o[c] -> adp[c] + Acetaminophenglu[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Acetaminophenglu |
Acetaminophenglu |
UidP |
Transport of D-Glucuronate Acetaminophen glucuronide |
Acetaminophenglu[e] -> Acetaminophenglu[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Acetaminophenglu |
Acetaminophenglu |
UidB |
Glucuronate transport in via proton symport Acetaminophen glucuronide |
Acetaminophenglu[e] + h[e] -> Acetaminophenglu[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Acetaminophenglu |
Acetaminophenglu |
UidB |
Glucuronate transport in via proton symport Acetaminophen glucuronide, periplasmatic |
Acetaminophenglu[p] + h[p] -> Acetaminophenglu[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Acetaminophenglu |
Acetaminophenglu |
n.a. |
Acetaminophen glucuronide diffusion extracellular to periplasm |
Acetaminophenglu[e] <=> Acetaminophenglu[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Acetaminophen |
Acetaminophen |
n.a. |
beta-glucuronidase reaction product export Acetaminophen |
Acetaminophen[c] -> Acetaminophen[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Acetaminophen |
Acetaminophen |
n.a. |
beta-glucuronidase reaction product export Acetaminophen, periplasmatic |
Acetaminophen[c] -> Acetaminophen[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Acetaminophen |
Acetaminophen |
n.a. |
acetaminophen/ paracetamol diffusion extracellular to periplasm |
Acetaminophen[e] <=> Acetaminophen[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB12010 |
R788 (Fostamatinib) |
R406 |
cALP |
Alkaline Phosphatase (Fostamatinib) |
R788 (Fostamatinib)[c] + o2[c] -> R406[c] + h[c] + pi[c] + co2[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 20371637 |
| DB12010 |
R788 (Fostamatinib) |
R406 |
ALP |
Glycerone Phosphate Phosphohydrolase (Fostamatinib) |
R788 (Fostamatinib)[e] + o2[e] -> R406[e] + h[c] + pi[e] + co2[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 20371637 |
| DB12010 |
R788 (Fostamatinib) |
R406 |
ALP |
Glycerone Phosphate Phosphohydrolase (Fostamatinib), periplasmatic |
o2[p] + R788 (Fostamatinib)[p] -> h[c] + pi[c] + co2[p] + R406[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00404 |
4-Hydroxyalprazolam_Glc |
4-Hydroxyalprazolam |
UidAc |
4-Hydroxyalprazolam Glucuronide beta-glucuronidase |
4-Hydroxyalprazolam_glc[c] + h2o[c] -> 4-Hydroxyalprazolam[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00404 |
4-Hydroxyalprazolam_Glc |
4-Hydroxyalprazolam |
UidAe |
4-Hydroxyalprazolam Glucuronide beta-glucuronidase extracellular |
4-Hydroxyalprazolam_glc[e] + h2o[e] -> 4-Hydroxyalprazolam[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00404 |
4-Hydroxyalprazolam_Glc |
4-Hydroxyalprazolam |
UidAe |
4-Hydroxyalprazolam Glucuronide beta-glucuronidase extracellular, periplasmatic |
4-Hydroxyalprazolam_glc[p] + h2o[p] -> 4-Hydroxyalprazolam[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00404 |
4-Hydroxyalprazolam_Glc |
4-Hydroxyalprazolam_Glc |
UidABC |
Predicted glucuronide ABC transporter 4-Hydroxyalprazolam Glucuronide |
atp[c] + 4-Hydroxyalprazolam_glc[e] + h2o[c] -> adp[c] + 4-Hydroxyalprazolam_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00404 |
4-Hydroxyalprazolam_Glc |
4-Hydroxyalprazolam_Glc |
UidP |
Transport of D-Glucuronate 4-Hydroxyalprazolam Glucuronide |
4-Hydroxyalprazolam_glc[e] -> 4-Hydroxyalprazolam_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00404 |
4-Hydroxyalprazolam_Glc |
4-Hydroxyalprazolam_Glc |
UidB |
Glucuronate transport in via proton symport 4-Hydroxyalprazolam Glucuronide |
4-Hydroxyalprazolam_glc[e] + h[e] -> 4-Hydroxyalprazolam_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00404 |
4-Hydroxyalprazolam_Glc |
4-Hydroxyalprazolam_Glc |
UidB |
Glucuronate transport in via proton symport 4-Hydroxyalprazolam Glucuronide, periplasmatic |
4-Hydroxyalprazolam_glc[p] + h[p] -> 4-Hydroxyalprazolam_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00404 |
4-Hydroxyalprazolam_Glc |
4-Hydroxyalprazolam_Glc |
n.a. |
4-Hydroxyalprazolam Glucuronide diffusion extracellular to periplasm |
4-Hydroxyalprazolam_glc[e] <=> 4-Hydroxyalprazolam_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00404 |
4-Hydroxyalprazolam |
4-Hydroxyalprazolam |
n.a. |
beta-glucuronidase reaction product export 4-Hydroxyalprazolam |
4-Hydroxyalprazolam[c] -> 4-Hydroxyalprazolam[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00404 |
4-Hydroxyalprazolam |
4-Hydroxyalprazolam |
n.a. |
beta-glucuronidase reaction product export 4-Hydroxyalprazolam, periplasmatic |
4-Hydroxyalprazolam[c] -> 4-Hydroxyalprazolam[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00404 |
4-Hydroxyalprazolam |
4-Hydroxyalprazolam |
n.a. |
4-Hydroxyalprazolam diffusion extracellular to periplasm |
4-Hydroxyalprazolam[e] <=> 4-Hydroxyalprazolam[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00404 |
Alpha-Hydroxyalprazolam_Glc |
Alpha-Hydroxyalprazolam |
UidAc |
Alpha-Hydroxyalprazolam Glucuronide beta-glucuronidase |
Alpha-Hydroxyalprazolam_glc[c] + h2o[c] -> Alpha-Hydroxyalprazolam[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00404 |
Alpha-Hydroxyalprazolam_Glc |
Alpha-Hydroxyalprazolam |
UidAe |
Alpha-Hydroxyalprazolam Glucuronide beta-glucuronidase extracellular |
Alpha-Hydroxyalprazolam_glc[e] + h2o[e] -> Alpha-Hydroxyalprazolam[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00404 |
Alpha-Hydroxyalprazolam_Glc |
Alpha-Hydroxyalprazolam |
UidAe |
Alpha-Hydroxyalprazolam Glucuronide beta-glucuronidase extracellular, periplasmatic |
Alpha-Hydroxyalprazolam_glc[p] + h2o[p] -> Alpha-Hydroxyalprazolam[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00404 |
Alpha-Hydroxyalprazolam_Glc |
Alpha-Hydroxyalprazolam_Glc |
UidABC |
Predicted glucuronide ABC transporter Alpha-Hydroxyalprazolam Glucuronide |
atp[c] + Alpha-Hydroxyalprazolam_glc[e] + h2o[c] -> adp[c] + Alpha-Hydroxyalprazolam_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00404 |
Alpha-Hydroxyalprazolam_Glc |
Alpha-Hydroxyalprazolam_Glc |
UidP |
Transport of D-Glucuronate Alpha-Hydroxyalprazolam Glucuronide |
Alpha-Hydroxyalprazolam_glc[e] -> Alpha-Hydroxyalprazolam_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00404 |
Alpha-Hydroxyalprazolam_Glc |
Alpha-Hydroxyalprazolam_Glc |
UidB |
Glucuronate transport in via proton symport Alpha-Hydroxyalprazolam Glucuronide |
Alpha-Hydroxyalprazolam_glc[e] + h[e] -> Alpha-Hydroxyalprazolam_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00404 |
Alpha-Hydroxyalprazolam_Glc |
Alpha-Hydroxyalprazolam_Glc |
UidB |
Glucuronate transport in via proton symport Alpha-Hydroxyalprazolam Glucuronide, periplasmatic |
Alpha-Hydroxyalprazolam_glc[p] + h[p] -> Alpha-Hydroxyalprazolam_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00404 |
Alpha-Hydroxyalprazolam_Glc |
Alpha-Hydroxyalprazolam_Glc |
n.a. |
Alpha-Hydroxyalprazolam Glucuronide diffusion extracellular to periplasm |
Alpha-Hydroxyalprazolam_glc[e] <=> Alpha-Hydroxyalprazolam_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00404 |
Alpha-Hydroxyalprazolam |
Alpha-Hydroxyalprazolam |
n.a. |
beta-glucuronidase reaction product export Alpha-Hydroxyalprazolam |
Alpha-Hydroxyalprazolam[c] -> Alpha-Hydroxyalprazolam[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00404 |
Alpha-Hydroxyalprazolam |
Alpha-Hydroxyalprazolam |
n.a. |
beta-glucuronidase reaction product export Alpha-Hydroxyalprazolam, periplasmatic |
Alpha-Hydroxyalprazolam[c] -> Alpha-Hydroxyalprazolam[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00404 |
Alpha-Hydroxyalprazolam |
Alpha-Hydroxyalprazolam |
n.a. |
Alpha-Hydroxyalprazolam diffusion extracellular to periplasm |
Alpha-Hydroxyalprazolam[e] <=> Alpha-Hydroxyalprazolam[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Desmethylalfentanil (Am14)_Glc |
Desmethylalfentanil (Am14) |
UidAc |
Desmethylalfentanil Glucuronide (AM14 Glucuronide) beta-glucuronidase |
Desmethylalfentanil (AM14)_glc[c] + h2o[c] -> Desmethylalfentanil (AM14)[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Desmethylalfentanil (Am14)_Glc |
Desmethylalfentanil (Am14) |
UidAe |
Desmethylalfentanil Glucuronide (AM14 Glucuronide) beta-glucuronidase extracellular |
Desmethylalfentanil (AM14)_glc[e] + h2o[e] -> Desmethylalfentanil (AM14)[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Desmethylalfentanil (Am14)_Glc |
Desmethylalfentanil (Am14) |
UidAe |
Desmethylalfentanil Glucuronide (AM14 Glucuronide) beta-glucuronidase extracellular, periplasmatic |
Desmethylalfentanil (AM14)_glc[p] + h2o[p] -> Desmethylalfentanil (AM14)[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Desmethylalfentanil (Am14)_Glc |
Desmethylalfentanil (Am14)_Glc |
UidABC |
Predicted glucuronide ABC transporter Desmethylalfentanil Glucuronide (AM14 Glucuronide) |
atp[c] + Desmethylalfentanil (AM14)_glc[e] + h2o[c] -> adp[c] + Desmethylalfentanil (AM14)_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Desmethylalfentanil (Am14)_Glc |
Desmethylalfentanil (Am14)_Glc |
UidP |
Transport of D-Glucuronate Desmethylalfentanil Glucuronide (AM14 Glucuronide) |
Desmethylalfentanil (AM14)_glc[e] -> Desmethylalfentanil (AM14)_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Desmethylalfentanil (Am14)_Glc |
Desmethylalfentanil (Am14)_Glc |
UidB |
Glucuronate transport in via proton symport Desmethylalfentanil Glucuronide (AM14 Glucuronide) |
Desmethylalfentanil (AM14)_glc[e] + h[e] -> Desmethylalfentanil (AM14)_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Desmethylalfentanil (Am14)_Glc |
Desmethylalfentanil (Am14)_Glc |
UidB |
Glucuronate transport in via proton symport Desmethylalfentanil Glucuronide (AM14 Glucuronide), periplasmatic |
Desmethylalfentanil (AM14)_glc[p] + h[p] -> Desmethylalfentanil (AM14)_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Desmethylalfentanil (Am14)_Glc |
Desmethylalfentanil (Am14)_Glc |
n.a. |
Desmethylalfentanil Glucuronide (AM14 Glucuronide) diffusion extracellular to periplasm |
Desmethylalfentanil (AM14)_glc[e] <=> Desmethylalfentanil (AM14)_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Desmethylalfentanil (Am14) |
Desmethylalfentanil (Am14) |
n.a. |
beta-glucuronidase reaction product export Desmethylalfentanil (AM14) |
Desmethylalfentanil (AM14)[c] -> Desmethylalfentanil (AM14)[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Desmethylalfentanil (Am14) |
Desmethylalfentanil (Am14) |
n.a. |
beta-glucuronidase reaction product export Desmethylalfentanil (AM14), periplasmatic |
Desmethylalfentanil (AM14)[c] -> Desmethylalfentanil (AM14)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Desmethylalfentanil (Am14) |
Desmethylalfentanil (Am14) |
n.a. |
Desmethylalfentanil (AM14) diffusion extracellular to periplasm |
Desmethylalfentanil (AM14)[e] <=> Desmethylalfentanil (AM14)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00091 |
Am1C (Cyclosporine) (M18) |
Am1C (Cyclosporine) (M18) |
n.a. |
beta-glucuronidase reaction product export AM1c (cyclosporine) |
AM1C (Cyclosporine) (M18)[c] -> AM1C (Cyclosporine) (M18)[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00091 |
Am1C (Cyclosporine) (M18) |
Am1C (Cyclosporine) (M18) |
n.a. |
beta-glucuronidase reaction product export AM1c (cyclosporine), periplasmatic |
AM1C (Cyclosporine) (M18)[c] -> AM1C (Cyclosporine) (M18)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00091 |
Am1C (Cyclosporine) (M18) |
Am1C (Cyclosporine) (M18) |
n.a. |
AM1c (cyclosporine) diffusion extracellular to periplasm |
AM1C (Cyclosporine) (M18)[e] <=> AM1C (Cyclosporine) (M18)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00091 |
Am1C-Glucuronide (Cyclosporine) |
Am1C (Cyclosporine) (M18) |
UidAc |
AM1c-glucuronide (cyclosporine) beta-glucuronidase |
AM1C-Glucuronide (Cyclosporine)[c] + h2o[c] -> AM1C (Cyclosporine) (M18)[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00091 |
Am1C-Glucuronide (Cyclosporine) |
Am1C (Cyclosporine) (M18) |
UidAe |
AM1c-glucuronide (cyclosporine) beta-glucuronidase extracellular |
AM1C-Glucuronide (Cyclosporine)[e] + h2o[e] -> AM1C (Cyclosporine) (M18)[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00091 |
Am1C-Glucuronide (Cyclosporine) |
Am1C (Cyclosporine) (M18) |
UidAe |
AM1c-glucuronide (cyclosporine) beta-glucuronidase extracellular, periplasmatic |
AM1C-Glucuronide (Cyclosporine)[p] + h2o[p] -> AM1C (Cyclosporine) (M18)[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00091 |
Am1C-Glucuronide (Cyclosporine) |
Am1C-Glucuronide (Cyclosporine) |
UidABC |
Predicted glucuronide ABC transporter AM1c-glucuronide (cyclosporine) |
atp[c] + AM1C-Glucuronide (Cyclosporine)[e] + h2o[c] -> adp[c] + AM1C-Glucuronide (Cyclosporine)[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00091 |
Am1C-Glucuronide (Cyclosporine) |
Am1C-Glucuronide (Cyclosporine) |
UidP |
Transport of D-Glucuronate AM1c-glucuronide (cyclosporine) |
AM1C-Glucuronide (Cyclosporine)[e] -> AM1C-Glucuronide (Cyclosporine)[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00091 |
Am1C-Glucuronide (Cyclosporine) |
Am1C-Glucuronide (Cyclosporine) |
UidB |
Glucuronate transport in via proton symport AM1c-glucuronide (cyclosporine) |
AM1C-Glucuronide (Cyclosporine)[e] + h[e] -> AM1C-Glucuronide (Cyclosporine)[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00091 |
Am1C-Glucuronide (Cyclosporine) |
Am1C-Glucuronide (Cyclosporine) |
UidB |
Glucuronate transport in via proton symport AM1c-glucuronide (cyclosporine), periplasmatic |
AM1C-Glucuronide (Cyclosporine)[p] + h[p] -> AM1C-Glucuronide (Cyclosporine)[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00091 |
Am1C-Glucuronide (Cyclosporine) |
Am1C-Glucuronide (Cyclosporine) |
n.a. |
AM1c-glucuronide (cyclosporine) diffusion extracellular to periplasm |
AM1C-Glucuronide (Cyclosporine)[e] <=> AM1C-Glucuronide (Cyclosporine)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
N-(4-Hydroxyphenyl)Propanamide (Am5)_Glc |
N-(4-Hydroxyphenyl)Propanamide (Am5) |
UidAc |
N-(4-Hydroxyphenyl)Propanamide Glucuronide (AM5 Glucuronide) beta-glucuronidase |
N-(4-Hydroxyphenyl)Propanamide (AM5)_glc[c] + h2o[c] -> N-(4-Hydroxyphenyl)Propanamide (AM5)[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
N-(4-Hydroxyphenyl)Propanamide (Am5)_Glc |
N-(4-Hydroxyphenyl)Propanamide (Am5) |
UidAe |
N-(4-Hydroxyphenyl)Propanamide Glucuronide (AM5 Glucuronide) beta-glucuronidase extracellular |
N-(4-Hydroxyphenyl)Propanamide (AM5)_glc[e] + h2o[e] -> N-(4-Hydroxyphenyl)Propanamide (AM5)[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
N-(4-Hydroxyphenyl)Propanamide (Am5)_Glc |
N-(4-Hydroxyphenyl)Propanamide (Am5) |
UidAe |
N-(4-Hydroxyphenyl)Propanamide Glucuronide (AM5 Glucuronide) beta-glucuronidase extracellular, periplasmatic |
N-(4-Hydroxyphenyl)Propanamide (AM5)_glc[p] + h2o[p] -> N-(4-Hydroxyphenyl)Propanamide (AM5)[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
N-(4-Hydroxyphenyl)Propanamide (Am5)_Glc |
N-(4-Hydroxyphenyl)Propanamide (Am5)_Glc |
UidABC |
Predicted glucuronide ABC transporter N-(4-Hydroxyphenyl)Propanamide Glucuronide (AM5 Glucuronide) |
atp[c] + N-(4-Hydroxyphenyl)Propanamide (AM5)_glc[e] + h2o[c] -> adp[c] + N-(4-Hydroxyphenyl)Propanamide (AM5)_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
N-(4-Hydroxyphenyl)Propanamide (Am5)_Glc |
N-(4-Hydroxyphenyl)Propanamide (Am5)_Glc |
UidP |
Transport of D-Glucuronate N-(4-Hydroxyphenyl)Propanamide Glucuronide (AM5 Glucuronide) |
N-(4-Hydroxyphenyl)Propanamide (AM5)_glc[e] -> N-(4-Hydroxyphenyl)Propanamide (AM5)_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
N-(4-Hydroxyphenyl)Propanamide (Am5)_Glc |
N-(4-Hydroxyphenyl)Propanamide (Am5)_Glc |
UidB |
Glucuronate transport in via proton symport N-(4-Hydroxyphenyl)Propanamide Glucuronide (AM5 Glucuronide) |
N-(4-Hydroxyphenyl)Propanamide (AM5)_glc[e] + h[e] -> N-(4-Hydroxyphenyl)Propanamide (AM5)_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
N-(4-Hydroxyphenyl)Propanamide (Am5)_Glc |
N-(4-Hydroxyphenyl)Propanamide (Am5)_Glc |
UidB |
Glucuronate transport in via proton symport N-(4-Hydroxyphenyl)Propanamide Glucuronide (AM5 Glucuronide), periplasmatic |
N-(4-Hydroxyphenyl)Propanamide (AM5)_glc[p] + h[p] -> N-(4-Hydroxyphenyl)Propanamide (AM5)_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
N-(4-Hydroxyphenyl)Propanamide (Am5)_Glc |
N-(4-Hydroxyphenyl)Propanamide (Am5)_Glc |
n.a. |
N-(4-Hydroxyphenyl)Propanamide Glucuronide (AM5 Glucuronide) diffusion extracellular to periplasm |
N-(4-Hydroxyphenyl)Propanamide (AM5)_glc[e] <=> N-(4-Hydroxyphenyl)Propanamide (AM5)_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
N-(4-Hydroxyphenyl)Propanamide (Am5) |
N-(4-Hydroxyphenyl)Propanamide (Am5) |
n.a. |
beta-glucuronidase reaction product export N-(4-Hydroxyphenyl)Propanamide (AM5) |
N-(4-Hydroxyphenyl)Propanamide (AM5)[c] -> N-(4-Hydroxyphenyl)Propanamide (AM5)[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
N-(4-Hydroxyphenyl)Propanamide (Am5) |
N-(4-Hydroxyphenyl)Propanamide (Am5) |
n.a. |
beta-glucuronidase reaction product export N-(4-Hydroxyphenyl)Propanamide (AM5), periplasmatic |
N-(4-Hydroxyphenyl)Propanamide (AM5)[c] -> N-(4-Hydroxyphenyl)Propanamide (AM5)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
N-(4-Hydroxyphenyl)Propanamide (Am5) |
N-(4-Hydroxyphenyl)Propanamide (Am5) |
n.a. |
N-(4-Hydroxyphenyl)Propanamide (AM5) diffusion extracellular to periplasm |
N-(4-Hydroxyphenyl)Propanamide (AM5)[e] <=> N-(4-Hydroxyphenyl)Propanamide (AM5)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Desmethylnoralfentanil (Am6)_Glc |
Desmethylnoralfentanil (Am6) |
UidAc |
Desmethylnoralfentanil Glucuronide (AM6 Glucuronide) beta-glucuronidase |
Desmethylnoralfentanil (AM6)_glc[c] + h2o[c] -> Desmethylnoralfentanil (AM6)[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Desmethylnoralfentanil (Am6)_Glc |
Desmethylnoralfentanil (Am6) |
UidAe |
Desmethylnoralfentanil Glucuronide (AM6 Glucuronide) beta-glucuronidase extracellular |
Desmethylnoralfentanil (AM6)_glc[e] + h2o[e] -> Desmethylnoralfentanil (AM6)[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Desmethylnoralfentanil (Am6)_Glc |
Desmethylnoralfentanil (Am6) |
UidAe |
Desmethylnoralfentanil Glucuronide (AM6 Glucuronide) beta-glucuronidase extracellular, periplasmatic |
Desmethylnoralfentanil (AM6)_glc[p] + h2o[p] -> Desmethylnoralfentanil (AM6)[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Desmethylnoralfentanil (Am6)_Glc |
Desmethylnoralfentanil (Am6)_Glc |
UidABC |
Predicted glucuronide ABC transporter Desmethylnoralfentanil Glucuronide (AM6 Glucuronide) |
atp[c] + Desmethylnoralfentanil (AM6)_glc[e] + h2o[c] -> adp[c] + Desmethylnoralfentanil (AM6)_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Desmethylnoralfentanil (Am6)_Glc |
Desmethylnoralfentanil (Am6)_Glc |
UidP |
Transport of D-Glucuronate Desmethylnoralfentanil Glucuronide (AM6 Glucuronide) |
Desmethylnoralfentanil (AM6)_glc[e] -> Desmethylnoralfentanil (AM6)_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Desmethylnoralfentanil (Am6)_Glc |
Desmethylnoralfentanil (Am6)_Glc |
UidB |
Glucuronate transport in via proton symport Desmethylnoralfentanil Glucuronide (AM6 Glucuronide) |
Desmethylnoralfentanil (AM6)_glc[e] + h[e] -> Desmethylnoralfentanil (AM6)_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Desmethylnoralfentanil (Am6)_Glc |
Desmethylnoralfentanil (Am6)_Glc |
UidB |
Glucuronate transport in via proton symport Desmethylnoralfentanil Glucuronide (AM6 Glucuronide), periplasmatic |
Desmethylnoralfentanil (AM6)_glc[p] + h[p] -> Desmethylnoralfentanil (AM6)_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Desmethylnoralfentanil (Am6)_Glc |
Desmethylnoralfentanil (Am6)_Glc |
n.a. |
Desmethylnoralfentanil Glucuronide (AM6 Glucuronide) diffusion extracellular to periplasm |
Desmethylnoralfentanil (AM6)_glc[e] <=> Desmethylnoralfentanil (AM6)_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Desmethylnoralfentanil (Am6) |
Desmethylnoralfentanil (Am6) |
n.a. |
beta-glucuronidase reaction product export Desmethylnoralfentanil (AM6) |
Desmethylnoralfentanil (AM6)[c] -> Desmethylnoralfentanil (AM6)[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Desmethylnoralfentanil (Am6) |
Desmethylnoralfentanil (Am6) |
n.a. |
beta-glucuronidase reaction product export Desmethylnoralfentanil (AM6), periplasmatic |
Desmethylnoralfentanil (AM6)[c] -> Desmethylnoralfentanil (AM6)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Desmethylnoralfentanil (Am6) |
Desmethylnoralfentanil (Am6) |
n.a. |
Desmethylnoralfentanil (AM6) diffusion extracellular to periplasm |
Desmethylnoralfentanil (AM6)[e] <=> Desmethylnoralfentanil (AM6)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Amiodarone_C_Glc |
Amiodarone_C |
UidAc |
Carboxylamiodarone Glucuronide (M19) beta-glucuronidase |
Amiodarone_c_glc[c] + h2o[c] -> Amiodarone_c[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Amiodarone_C_Glc |
Amiodarone_C |
UidAe |
Carboxylamiodarone Glucuronide (M19) beta-glucuronidase extracellular |
Amiodarone_c_glc[e] + h2o[e] -> Amiodarone_c[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Amiodarone_C_Glc |
Amiodarone_C |
UidAe |
Carboxylamiodarone Glucuronide (M19) beta-glucuronidase extracellular, periplasmatic |
Amiodarone_c_glc[p] + h2o[p] -> Amiodarone_c[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Amiodarone_C_Glc |
Amiodarone_C_Glc |
UidABC |
Predicted glucuronide ABC transporter Carboxylamiodarone Glucuronide (M19) |
atp[c] + Amiodarone_c_glc[e] + h2o[c] -> adp[c] + Amiodarone_c_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Amiodarone_C_Glc |
Amiodarone_C_Glc |
UidP |
Transport of D-Glucuronate Carboxylamiodarone Glucuronide (M19) |
Amiodarone_c_glc[e] -> Amiodarone_c_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Amiodarone_C_Glc |
Amiodarone_C_Glc |
UidB |
Glucuronate transport in via proton symport Carboxylamiodarone Glucuronide (M19) |
Amiodarone_c_glc[e] + h[e] -> Amiodarone_c_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Amiodarone_C_Glc |
Amiodarone_C_Glc |
UidB |
Glucuronate transport in via proton symport Carboxylamiodarone Glucuronide (M19), periplasmatic |
Amiodarone_c_glc[p] + h[p] -> Amiodarone_c_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Amiodarone_C_Glc |
Amiodarone_C_Glc |
n.a. |
Carboxylamiodarone Glucuronide (M19) diffusion extracellular to periplasm |
Amiodarone_c_glc[e] <=> Amiodarone_c_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Amiodarone_C |
Amiodarone_C |
n.a. |
beta-glucuronidase reaction product export Carboxylamiodarone (M12) |
Amiodarone_c[c] -> Amiodarone_c[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Amiodarone_C |
Amiodarone_C |
n.a. |
beta-glucuronidase reaction product export Carboxylamiodarone (M12), periplasmatic |
Amiodarone_c[c] -> Amiodarone_c[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Amiodarone_C |
Amiodarone_C |
n.a. |
Carboxylamiodarone (M12) diffusion extracellular to periplasm |
Amiodarone_c[e] <=> Amiodarone_c[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
Amiodarone_Glc |
Amiodarone |
UidAc |
Amiodarone Glucuronide (M16) beta-glucuronidase |
Amiodarone_glc[c] + h2o[c] -> Amiodarone[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01118 |
Amiodarone_Glc |
Amiodarone |
UidAe |
Amiodarone Glucuronide (M16) beta-glucuronidase extracellular |
Amiodarone_glc[e] + h2o[e] -> Amiodarone[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01118 |
Amiodarone_Glc |
Amiodarone |
UidAe |
Amiodarone Glucuronide (M16) beta-glucuronidase extracellular, periplasmatic |
Amiodarone_glc[p] + h2o[p] -> Amiodarone[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01118 |
Amiodarone_Glc |
Amiodarone_Glc |
UidABC |
Predicted glucuronide ABC transporter Amiodarone Glucuronide (M16) |
atp[c] + Amiodarone_glc[e] + h2o[c] -> adp[c] + Amiodarone_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
Amiodarone_Glc |
Amiodarone_Glc |
UidP |
Transport of D-Glucuronate Amiodarone Glucuronide (M16) |
Amiodarone_glc[e] -> Amiodarone_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
Amiodarone_Glc |
Amiodarone_Glc |
UidB |
Glucuronate transport in via proton symport Amiodarone Glucuronide (M16) |
Amiodarone_glc[e] + h[e] -> Amiodarone_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
Amiodarone_Glc |
Amiodarone_Glc |
UidB |
Glucuronate transport in via proton symport Amiodarone Glucuronide (M16), periplasmatic |
Amiodarone_glc[p] + h[p] -> Amiodarone_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
Amiodarone_Glc |
Amiodarone_Glc |
n.a. |
Amiodarone Glucuronide (M16) diffusion extracellular to periplasm |
Amiodarone_glc[e] <=> Amiodarone_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
Amiodarone |
Amiodarone |
n.a. |
beta-glucuronidase reaction product export Amiodarone |
Amiodarone[c] -> Amiodarone[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
Amiodarone |
Amiodarone |
n.a. |
beta-glucuronidase reaction product export Amiodarone, periplasmatic |
Amiodarone[c] -> Amiodarone[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
Amiodarone |
Amiodarone |
n.a. |
Amiodarone diffusion extracellular to periplasm |
Amiodarone[e] <=> Amiodarone[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00145 |
4-Aminobenzoylglycinecine_Glc |
4-Aminobenzoylglycinecine |
UidAc |
4-Aminobenzoylglycine Glucuronide beta-glucuronidase |
4-AminobenzoylGlycinecine_glc[c] + h2o[c] -> 4-AminobenzoylGlycinecine[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00145 |
4-Aminobenzoylglycinecine_Glc |
4-Aminobenzoylglycinecine |
UidAe |
4-Aminobenzoylglycine Glucuronide beta-glucuronidase extracellular |
4-AminobenzoylGlycinecine_glc[e] + h2o[e] -> 4-AminobenzoylGlycinecine[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00145 |
4-Aminobenzoylglycinecine_Glc |
4-Aminobenzoylglycinecine |
UidAe |
4-Aminobenzoylglycine Glucuronide beta-glucuronidase extracellular, periplasmatic |
4-AminobenzoylGlycinecine_glc[p] + h2o[p] -> 4-AminobenzoylGlycinecine[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00145 |
4-Aminobenzoylglycinecine_Glc |
4-Aminobenzoylglycinecine_Glc |
UidABC |
Predicted glucuronide ABC transporter 4-Aminobenzoylglycine Glucuronide |
atp[c] + 4-AminobenzoylGlycinecine_glc[e] + h2o[c] -> adp[c] + 4-AminobenzoylGlycinecine_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00145 |
4-Aminobenzoylglycinecine_Glc |
4-Aminobenzoylglycinecine_Glc |
UidP |
Transport of D-Glucuronate 4-Aminobenzoylglycine Glucuronide |
4-AminobenzoylGlycinecine_glc[e] -> 4-AminobenzoylGlycinecine_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00145 |
4-Aminobenzoylglycinecine_Glc |
4-Aminobenzoylglycinecine_Glc |
UidB |
Glucuronate transport in via proton symport 4-Aminobenzoylglycine Glucuronide |
4-AminobenzoylGlycinecine_glc[e] + h[e] -> 4-AminobenzoylGlycinecine_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00145 |
4-Aminobenzoylglycinecine_Glc |
4-Aminobenzoylglycinecine_Glc |
UidB |
Glucuronate transport in via proton symport 4-Aminobenzoylglycine Glucuronide, periplasmatic |
4-AminobenzoylGlycinecine_glc[p] + h[p] -> 4-AminobenzoylGlycinecine_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00145 |
4-Aminobenzoylglycinecine_Glc |
4-Aminobenzoylglycinecine_Glc |
n.a. |
4-Aminobenzoylglycine Glucuronide diffusion extracellular to periplasm |
4-AminobenzoylGlycinecine_glc[e] <=> 4-AminobenzoylGlycinecine_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00145 |
4-Aminobenzoylglycinecine |
4-Aminobenzoylglycinecine |
n.a. |
beta-glucuronidase reaction product export 4-Aminobenzoylglycine |
4-AminobenzoylGlycinecine[c] -> 4-AminobenzoylGlycinecine[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00145 |
4-Aminobenzoylglycinecine |
4-Aminobenzoylglycinecine |
n.a. |
beta-glucuronidase reaction product export 4-Aminobenzoylglycine, periplasmatic |
4-AminobenzoylGlycinecine[c] -> 4-AminobenzoylGlycinecine[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00145 |
4-Aminobenzoylglycinecine |
4-Aminobenzoylglycinecine |
n.a. |
4-Aminobenzoylglycine diffusion extracellular to periplasm |
4-AminobenzoylGlycinecine[e] <=> 4-AminobenzoylGlycinecine[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00915 |
Oxidation Product Of M3 M6_Glc |
Oxidation Product Of M3 M6 |
UidAc |
Amantadine M6 Glucuronide beta-glucuronidase |
Oxidation Product Of M3 M6_glc[c] + h2o[c] -> Oxidation Product Of M3 M6[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00915 |
Oxidation Product Of M3 M6_Glc |
Oxidation Product Of M3 M6 |
UidAe |
Amantadine M6 Glucuronide beta-glucuronidase extracellular |
Oxidation Product Of M3 M6_glc[e] + h2o[e] -> Oxidation Product Of M3 M6[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00915 |
Oxidation Product Of M3 M6_Glc |
Oxidation Product Of M3 M6 |
UidAe |
Amantadine M6 Glucuronide beta-glucuronidase extracellular, periplasmatic |
Oxidation Product Of M3 M6_glc[p] + h2o[p] -> Oxidation Product Of M3 M6[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00915 |
Oxidation Product Of M3 M6_Glc |
Oxidation Product Of M3 M6_Glc |
UidABC |
Predicted glucuronide ABC transporter Amantadine M6 Glucuronide |
atp[c] + Oxidation Product Of M3 M6_glc[e] + h2o[c] -> adp[c] + Oxidation Product Of M3 M6_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00915 |
Oxidation Product Of M3 M6_Glc |
Oxidation Product Of M3 M6_Glc |
UidP |
Transport of D-Glucuronate Amantadine M6 Glucuronide |
Oxidation Product Of M3 M6_glc[e] -> Oxidation Product Of M3 M6_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00915 |
Oxidation Product Of M3 M6_Glc |
Oxidation Product Of M3 M6_Glc |
UidB |
Glucuronate transport in via proton symport Amantadine M6 Glucuronide |
Oxidation Product Of M3 M6_glc[e] + h[e] -> Oxidation Product Of M3 M6_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00915 |
Oxidation Product Of M3 M6_Glc |
Oxidation Product Of M3 M6_Glc |
UidB |
Glucuronate transport in via proton symport Amantadine M6 Glucuronide, periplasmatic |
Oxidation Product Of M3 M6_glc[p] + h[p] -> Oxidation Product Of M3 M6_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00915 |
Oxidation Product Of M3 M6_Glc |
Oxidation Product Of M3 M6_Glc |
n.a. |
Amantadine M6 Glucuronide diffusion extracellular to periplasm |
Oxidation Product Of M3 M6_glc[e] <=> Oxidation Product Of M3 M6_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00915 |
Oxidation Product Of M3 M6 |
Oxidation Product Of M3 M6 |
n.a. |
beta-glucuronidase reaction product export Oxidation Product Of M3 M6 |
Oxidation Product Of M3 M6[c] -> Oxidation Product Of M3 M6[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00915 |
Oxidation Product Of M3 M6 |
Oxidation Product Of M3 M6 |
n.a. |
beta-glucuronidase reaction product export Oxidation Product Of M3 M6, periplasmatic |
Oxidation Product Of M3 M6[c] -> Oxidation Product Of M3 M6[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00915 |
Oxidation Product Of M3 M6 |
Oxidation Product Of M3 M6 |
n.a. |
Oxidation Product Of M3 M6 diffusion extracellular to periplasm |
Oxidation Product Of M3 M6[e] <=> Oxidation Product Of M3 M6[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid |
n.a. |
beta-glucuronidase reaction product export atorvastatin-acid |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid[c] -> atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid |
n.a. |
beta-glucuronidase reaction product export atorvastatin-acid, periplasmatic |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid[c] -> atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid |
n.a. |
atorvastatin-acid diffusion extracellular to periplasm |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid[e] <=> atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acyl-Glucuronide / G2 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone |
UidAc |
atorvastatin-acyl-glucuronide / G2 beta-glucuronidase |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acyl-glucuronide / G2[c] -> atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acyl-Glucuronide / G2 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone |
UidAe |
atorvastatin-acyl-glucuronide / G2 beta-glucuronidase extracellular |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acyl-glucuronide / G2[e] -> atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acyl-Glucuronide / G2 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone |
UidAe |
atorvastatin-acyl-glucuronide / G2 beta-glucuronidase extracellular, periplasmatic |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acyl-glucuronide / G2[p] -> atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acyl-Glucuronide / G2 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acyl-Glucuronide / G2 |
UidABC |
Predicted glucuronide ABC transporter atorvastatin-acyl-glucuronide / G2 |
atp[c] + atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acyl-glucuronide / G2[e] + h2o[c] -> adp[c] + atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acyl-glucuronide / G2[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acyl-Glucuronide / G2 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acyl-Glucuronide / G2 |
UidP |
Transport of D-Glucuronate atorvastatin-acyl-glucuronide / G2 |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acyl-glucuronide / G2[e] -> atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acyl-glucuronide / G2[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acyl-Glucuronide / G2 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acyl-Glucuronide / G2 |
UidB |
Glucuronate transport in via proton symport atorvastatin-acyl-glucuronide / G2 |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acyl-glucuronide / G2[e] + h[e] -> atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acyl-glucuronide / G2[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acyl-Glucuronide / G2 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acyl-Glucuronide / G2 |
UidB |
Glucuronate transport in via proton symport atorvastatin-acyl-glucuronide / G2, periplasmatic |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acyl-glucuronide / G2[p] + h[p] -> atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acyl-glucuronide / G2[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acyl-Glucuronide / G2 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acyl-Glucuronide / G2 |
n.a. |
atorvastatin-acyl-glucuronide / G2 diffusion extracellular to periplasm |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acyl-glucuronide / G2[e] <=> atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acyl-glucuronide / G2[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Ether-Glucuronide -G1 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid |
UidAc |
atorvastatin-ether-glucuronide -G1 beta-glucuronidase |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-ether-glucuronide -G1[c] + 2 h2o[c] -> atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid[c] + 2 glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Ether-Glucuronide -G1 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid |
UidAe |
atorvastatin-ether-glucuronide -G1 beta-glucuronidase extracellular |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-ether-glucuronide -G1[e] + 2 h2o[e] -> atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid[e] + 2 glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Ether-Glucuronide -G1 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid |
UidAe |
atorvastatin-ether-glucuronide -G1 beta-glucuronidase extracellular, periplasmatic |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-ether-glucuronide -G1[p] + 2 h2o[p] -> atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid[p] + 2 glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Ether-Glucuronide -G1 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Ether-Glucuronide -G1 |
UidABC |
Predicted glucuronide ABC transporter atorvastatin-ether-glucuronide -G1 |
atp[c] + atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-ether-glucuronide -G1[e] + h2o[c] -> adp[c] + atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-ether-glucuronide -G1[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Ether-Glucuronide -G1 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Ether-Glucuronide -G1 |
UidP |
Transport of D-Glucuronate atorvastatin-ether-glucuronide -G1 |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-ether-glucuronide -G1[e] -> atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-ether-glucuronide -G1[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Ether-Glucuronide -G1 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Ether-Glucuronide -G1 |
UidB |
Glucuronate transport in via proton symport atorvastatin-ether-glucuronide -G1 |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-ether-glucuronide -G1[e] + h[e] -> atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-ether-glucuronide -G1[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Ether-Glucuronide -G1 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Ether-Glucuronide -G1 |
UidB |
Glucuronate transport in via proton symport atorvastatin-ether-glucuronide -G1, periplasmatic |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-ether-glucuronide -G1[p] + h[p] -> atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-ether-glucuronide -G1[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Ether-Glucuronide -G1 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Ether-Glucuronide -G1 |
n.a. |
atorvastatin-ether-glucuronide -G1 diffusion extracellular to periplasm |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-ether-glucuronide -G1[e] <=> atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-ether-glucuronide -G1[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactonegluc |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone |
UidAc |
atorvastatin-lactone-ether-glucuronide / G3 beta-glucuronidase |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactonegluc[c] + h2o[c] -> atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 25193495 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactonegluc |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone |
UidAe |
atorvastatin-lactone-ether-glucuronide / G3 beta-glucuronidase extracellular |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactonegluc[e] + h2o[e] -> atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactonegluc |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone |
UidAe |
atorvastatin-lactone-ether-glucuronide / G3 beta-glucuronidase extracellular, periplasmatic |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactonegluc[p] + h2o[p] -> atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactonegluc |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactonegluc |
UidABC |
Predicted glucuronide ABC transporter atorvastatin-lactone-ether-glucuronide / G3 |
atp[c] + atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactonegluc[e] + h2o[c] -> adp[c] + atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactonegluc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactonegluc |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactonegluc |
UidP |
Transport of D-Glucuronate atorvastatin-lactone-ether-glucuronide / G3 |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactonegluc[e] -> atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactonegluc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactonegluc |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactonegluc |
UidB |
Glucuronate transport in via proton symport atorvastatin-lactone-ether-glucuronide / G3 |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactonegluc[e] + h[e] -> atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactonegluc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactonegluc |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactonegluc |
UidB |
Glucuronate transport in via proton symport atorvastatin-lactone-ether-glucuronide / G3, periplasmatic |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactonegluc[p] + h[p] -> atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactonegluc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactonegluc |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactonegluc |
n.a. |
atorvastatin-lactone-ether-glucuronide / G3 diffusion extracellular to periplasm |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactonegluc[e] <=> atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactonegluc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone |
n.a. |
beta-glucuronidase reaction product export atorvastatin-lactone |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone[c] -> atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone |
n.a. |
beta-glucuronidase reaction product export atorvastatin-lactone, periplasmatic |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone[c] -> atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone |
n.a. |
atorvastatin-lactone diffusion extracellular to periplasm |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone[e] <=> atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB15994 |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane_Glc |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane |
UidAc |
Bis-(P-Hydroxy-Phenyl)-Pyridyl-2-Methane Glucuronide beta-glucuronidase |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane_glc[c] + h2o[c] -> (Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB15994 |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane_Glc |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane |
UidAe |
Bis-(P-Hydroxy-Phenyl)-Pyridyl-2-Methane Glucuronide beta-glucuronidase extracellular |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane_glc[e] + h2o[e] -> (Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB15994 |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane_Glc |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane |
UidAe |
Bis-(P-Hydroxy-Phenyl)-Pyridyl-2-Methane Glucuronide beta-glucuronidase extracellular, periplasmatic |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane_glc[p] + h2o[p] -> (Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB15994 |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane_Glc |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane_Glc |
UidABC |
Predicted glucuronide ABC transporter Bis-(P-Hydroxy-Phenyl)-Pyridyl-2-Methane Glucuronide |
atp[c] + (Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane_glc[e] + h2o[c] -> adp[c] + (Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB15994 |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane_Glc |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane_Glc |
UidP |
Transport of D-Glucuronate Bis-(P-Hydroxy-Phenyl)-Pyridyl-2-Methane Glucuronide |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane_glc[e] -> (Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB15994 |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane_Glc |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane_Glc |
UidB |
Glucuronate transport in via proton symport Bis-(P-Hydroxy-Phenyl)-Pyridyl-2-Methane Glucuronide |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane_glc[e] + h[e] -> (Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB15994 |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane_Glc |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane_Glc |
UidB |
Glucuronate transport in via proton symport Bis-(P-Hydroxy-Phenyl)-Pyridyl-2-Methane Glucuronide, periplasmatic |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane_glc[p] + h[p] -> (Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB15994 |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane_Glc |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane_Glc |
n.a. |
Bis-(P-Hydroxy-Phenyl)-Pyridyl-2-Methane Glucuronide diffusion extracellular to periplasm |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane_glc[e] <=> (Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB15994 |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane |
n.a. |
beta-glucuronidase reaction product export (Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane[c] -> (Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB15994 |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane |
n.a. |
beta-glucuronidase reaction product export (Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane, periplasmatic |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane[c] -> (Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB15994 |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane |
n.a. |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane diffusion extracellular to periplasm |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane[e] <=> (Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr 355 |
Bilr 355 |
n.a. |
beta-glucuronidase reaction product export BILR 355 |
BILR 355[c] -> BILR 355[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr 355 |
Bilr 355 |
n.a. |
beta-glucuronidase reaction product export BILR 355, periplasmatic |
BILR 355[c] -> BILR 355[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr 355 |
Bilr 355 |
n.a. |
BILR 355 diffusion extracellular to periplasm |
BILR 355[e] <=> BILR 355[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M10 |
Bilr 355 |
UidAc |
BILR M10 beta-glucuronidase |
BILR M10[c] + h2o[c] -> BILR 355[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M10 |
Bilr 355 |
UidAe |
BILR M10 beta-glucuronidase extracellular |
BILR M10[e] + h2o[e] -> BILR 355[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M10 |
Bilr 355 |
UidAe |
BILR M10 beta-glucuronidase extracellular, periplasmatic |
BILR M10[p] + h2o[p] -> BILR 355[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M10 |
Bilr M10 |
UidABC |
Predicted glucuronide ABC transporter BILR M10 |
atp[c] + BILR M10[e] + h2o[c] -> adp[c] + BILR M10[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M10 |
Bilr M10 |
UidP |
Transport of D-Glucuronate BILR M10 |
BILR M10[e] -> BILR M10[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M10 |
Bilr M10 |
UidB |
Glucuronate transport in via proton symport BILR M10 |
BILR M10[e] + h[e] -> BILR M10[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M10 |
Bilr M10 |
UidB |
Glucuronate transport in via proton symport BILR M10, periplasmatic |
BILR M10[p] + h[p] -> BILR M10[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M10 |
Bilr M10 |
n.a. |
BILR M10 diffusion extracellular to periplasm |
BILR M10[e] <=> BILR M10[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M12 |
Bilr M7 |
UidAc |
BILR M12 beta-glucuronidase |
BILR M12[c] + h2o[c] -> BILR M7[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M12 |
Bilr M7 |
UidAe |
BILR M12 beta-glucuronidase extracellular |
BILR M12[e] + h2o[e] -> BILR M7[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M12 |
Bilr M7 |
UidAe |
BILR M12 beta-glucuronidase extracellular, periplasmatic |
BILR M12[p] + h2o[p] -> BILR M7[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M12 |
Bilr M12 |
UidABC |
Predicted glucuronide ABC transporter BILR M12 |
atp[c] + BILR M12[e] + h2o[c] -> adp[c] + BILR M12[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M12 |
Bilr M12 |
UidP |
Transport of D-Glucuronate BILR M12 |
BILR M12[e] -> BILR M12[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M12 |
Bilr M12 |
UidB |
Glucuronate transport in via proton symport BILR M12 |
BILR M12[e] + h[e] -> BILR M12[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M12 |
Bilr M12 |
UidB |
Glucuronate transport in via proton symport BILR M12, periplasmatic |
BILR M12[p] + h[p] -> BILR M12[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M12 |
Bilr M12 |
n.a. |
BILR M12 diffusion extracellular to periplasm |
BILR M12[e] <=> BILR M12[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M14 |
Bilr M14 |
n.a. |
beta-glucuronidase reaction product export BILR M14 |
BILR M14[c] -> BILR M14[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M14 |
Bilr M14 |
n.a. |
beta-glucuronidase reaction product export BILR M14, periplasmatic |
BILR M14[c] -> BILR M14[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M14 |
Bilr M14 |
n.a. |
BILR M14 diffusion extracellular to periplasm |
BILR M14[e] <=> BILR M14[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M15 |
Bilr M14 |
UidAc |
BILR M15 beta-glucuronidase |
BILR M15[c] + h2o[c] -> BILR M14[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M15 |
Bilr M14 |
UidAe |
BILR M15 beta-glucuronidase extracellular |
BILR M15[e] + h2o[e] -> BILR M14[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M15 |
Bilr M14 |
UidAe |
BILR M15 beta-glucuronidase extracellular, periplasmatic |
BILR M15[p] + h2o[p] -> BILR M14[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M15 |
Bilr M15 |
UidABC |
Predicted glucuronide ABC transporter BILR M15 |
atp[c] + BILR M15[e] + h2o[c] -> adp[c] + BILR M15[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M15 |
Bilr M15 |
UidP |
Transport of D-Glucuronate BILR M15 |
BILR M15[e] -> BILR M15[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M15 |
Bilr M15 |
UidB |
Glucuronate transport in via proton symport BILR M15 |
BILR M15[e] + h[e] -> BILR M15[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M15 |
Bilr M15 |
UidB |
Glucuronate transport in via proton symport BILR M15, periplasmatic |
BILR M15[p] + h[p] -> BILR M15[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M15 |
Bilr M15 |
n.a. |
BILR M15 diffusion extracellular to periplasm |
BILR M15[e] <=> BILR M15[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M16 |
Bilr 355 |
UidAc |
BILR M16 beta-glucuronidase |
BILR M16[c] + h2o[c] -> BILR 355[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M16 |
Bilr 355 |
UidAe |
BILR M16 beta-glucuronidase extracellular |
BILR M16[e] + h2o[e] -> BILR 355[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M16 |
Bilr 355 |
UidAe |
BILR M16 beta-glucuronidase extracellular, periplasmatic |
BILR M16[p] + h2o[p] -> BILR 355[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M16 |
Bilr M16 |
UidABC |
Predicted glucuronide ABC transporter BILR M16 |
atp[c] + BILR M16[e] + h2o[c] -> adp[c] + BILR M16[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M16 |
Bilr M16 |
UidP |
Transport of D-Glucuronate BILR M16 |
BILR M16[e] -> BILR M16[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M16 |
Bilr M16 |
UidB |
Glucuronate transport in via proton symport BILR M16 |
BILR M16[e] + h[e] -> BILR M16[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M16 |
Bilr M16 |
UidB |
Glucuronate transport in via proton symport BILR M16, periplasmatic |
BILR M16[p] + h[p] -> BILR M16[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M16 |
Bilr M16 |
n.a. |
BILR M16 diffusion extracellular to periplasm |
BILR M16[e] <=> BILR M16[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M7 |
Bilr M7 |
n.a. |
beta-glucuronidase reaction product export BILR M7 |
BILR M7[c] -> BILR M7[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M7 |
Bilr M7 |
n.a. |
beta-glucuronidase reaction product export BILR M7, periplasmatic |
BILR M7[c] -> BILR M7[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M7 |
Bilr M7 |
n.a. |
BILR M7 diffusion extracellular to periplasm |
BILR M7[e] <=> BILR M7[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB03312 |
Brivudine |
Brivudine |
n.a. |
Brivudine transport in via proton symport |
h[e] + Brivudine[e] -> h[c] + Brivudine[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB03312 |
Brivudine |
Brivudine |
n.a. |
Brivudine transport in via proton symport, periplasmatic |
Brivudine[p] + h[p] -> Brivudine[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB03312 |
Brivudine |
Brivudine |
n.a. |
Brivudine diffusion extracellular to periplasm |
Brivudine[e] <=> Brivudine[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00559 |
Bosentan_Glc |
Bosentan |
UidAc |
Bosentan Glucuronide beta-glucuronidase |
Bosentan_glc[c] + h2o[c] -> Bosentan[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00559 |
Bosentan_Glc |
Bosentan |
UidAe |
Bosentan Glucuronide beta-glucuronidase extracellular |
Bosentan_glc[e] + h2o[e] -> Bosentan[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00559 |
Bosentan_Glc |
Bosentan |
UidAe |
Bosentan Glucuronide beta-glucuronidase extracellular, periplasmatic |
Bosentan_glc[p] + h2o[p] -> Bosentan[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00559 |
Bosentan_Glc |
Bosentan_Glc |
UidABC |
Predicted glucuronide ABC transporter Bosentan Glucuronide |
atp[c] + Bosentan_glc[e] + h2o[c] -> adp[c] + Bosentan_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00559 |
Bosentan_Glc |
Bosentan_Glc |
UidP |
Transport of D-Glucuronate Bosentan Glucuronide |
Bosentan_glc[e] -> Bosentan_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00559 |
Bosentan_Glc |
Bosentan_Glc |
UidB |
Glucuronate transport in via proton symport Bosentan Glucuronide |
Bosentan_glc[e] + h[e] -> Bosentan_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00559 |
Bosentan_Glc |
Bosentan_Glc |
UidB |
Glucuronate transport in via proton symport Bosentan Glucuronide, periplasmatic |
Bosentan_glc[p] + h[p] -> Bosentan_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00559 |
Bosentan_Glc |
Bosentan_Glc |
n.a. |
Bosentan Glucuronide diffusion extracellular to periplasm |
Bosentan_glc[e] <=> Bosentan_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00559 |
Bosentan |
Bosentan |
n.a. |
beta-glucuronidase reaction product export Bosentan |
Bosentan[c] -> Bosentan[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00559 |
Bosentan |
Bosentan |
n.a. |
beta-glucuronidase reaction product export Bosentan, periplasmatic |
Bosentan[c] -> Bosentan[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00559 |
Bosentan |
Bosentan |
n.a. |
Bosentan diffusion extracellular to periplasm |
Bosentan[e] <=> Bosentan[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB03419 |
(E)-5-(2-Bromovinyl)Uracil |
(E)-5-(2-Bromovinyl)Uracil |
n.a. |
(E)-5-(2-Bromovinyl)Uracil export |
(E)-5-(2-Bromovinyl)Uracil[c] -> (E)-5-(2-Bromovinyl)Uracil[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB03419 |
(E)-5-(2-Bromovinyl)Uracil |
(E)-5-(2-Bromovinyl)Uracil |
n.a. |
(E)-5-(2-Bromovinyl)Uracil export, periplasmatic |
(E)-5-(2-Bromovinyl)Uracil[c] -> (E)-5-(2-Bromovinyl)Uracil[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB03419 |
(E)-5-(2-Bromovinyl)Uracil |
(E)-5-(2-Bromovinyl)Uracil |
n.a. |
(E)-5-(2-Bromovinyl)Uracil diffusion extracellular to periplasm |
(E)-5-(2-Bromovinyl)Uracil[e] <=> (E)-5-(2-Bromovinyl)Uracil[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Benzoate_Glc |
Benzoate |
UidAc |
Benzoic Acid Glucuronide beta-glucuronidase |
Benzoate_glc[c] + h2o[c] -> Benzoate[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 7169611 |
| n.a. |
Benzoate_Glc |
Benzoate |
UidAe |
Benzoic acid glucuronide beta-glucuronidase extracellular |
Benzoate_glc[e] + h2o[e] -> Benzoate[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 7169611 |
| n.a. |
Benzoate_Glc |
Benzoate |
UidAe |
Benzoic acid glucuronide beta-glucuronidase extracellular, periplasmatic |
Benzoate_glc[p] + h2o[p] -> Benzoate[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 7169611 |
| n.a. |
Benzoate_Glc |
Benzoate_Glc |
UidABC |
Predicted glucuronide ABC transporter Benzoic Acid Glucuronide |
atp[c] + Benzoate_glc[e] + h2o[c] -> adp[c] + Benzoate_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Benzoate_Glc |
Benzoate_Glc |
UidP |
Transport of D-Glucuronate Benzoic acid glucuronide |
Benzoate_glc[e] -> Benzoate_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Benzoate_Glc |
Benzoate_Glc |
UidB |
Glucuronate transport in via proton symport Benzoic Acid Glucuronide |
Benzoate_glc[e] + h[e] -> Benzoate_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Benzoate_Glc |
Benzoate_Glc |
UidB |
Glucuronate transport in via proton symport Benzoic Acid Glucuronide, periplasmatic |
Benzoate_glc[p] + h[p] -> Benzoate_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Benzoate_Glc |
Benzoate_Glc |
n.a. |
Benzoic Acid Glucuronide diffusion extracellular to periplasm |
Benzoate_glc[e] <=> Benzoate_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Benzoated |
4-Aminobenzoyl-Beta-Alanine |
AzNAD |
Balsalazide Microbiota azo-reduction (NAD) |
Benzoated[c] + 2 nadh[c] + 2 h[c] -> 4-Aminobenzoyl-Beta-Alanine[c] + 5-Aminosalicylic Acid (Mesalamine)[c] + 2 nad[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 25091594, PMID: 26261286 |
| n.a. |
Benzoated |
4-Aminobenzoyl-Beta-Alanine |
AzNADP |
Balsalazide Microbiota azo-reduction (NADP) |
Benzoated[c] + 2 nadph[c] + 2 h[c] -> 4-Aminobenzoyl-Beta-Alanine[c] + 5-Aminosalicylic Acid (Mesalamine)[c] + 2 nadp[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 25091594, PMID: 26261286 |
| DB01014 |
Benzoated |
Benzoated |
AzorDMT |
Balsalazide transport via proton symport |
Benzoated[e] + h[e] <=> Benzoated[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01014 |
Benzoated |
Benzoated |
AzorDMT |
Balsalazide transport via proton symport, periplasmatic |
Benzoated[p] + h[p] <=> Benzoated[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01014 |
Benzoated |
Benzoated |
n.a. |
Balsalazide diffusion extracellular to periplasm |
Benzoated[e] <=> Benzoated[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Benzoate |
Benzoate |
n.a. |
beta-glucuronidase reaction product export Benzoate |
Benzoate[c] -> Benzoate[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Benzoate |
Benzoate |
n.a. |
beta-glucuronidase reaction product export Benzoate, periplasmatic |
Benzoate[c] -> Benzoate[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Benzoate |
Benzoate |
n.a. |
benzoate diffusion extracellular to periplasm |
Benzoate[e] <=> Benzoate[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Benzoate |
Benzoate |
n.a. |
Benzoate Transport (Diffusion), periplasmatic |
Benzoate[p] <=> Benzoate[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00446 |
Chloramphenicol |
Nchloramphenicol |
Nit |
Chloramphenicol Microbiota nitroreduction |
Chloramphenicol[c] + nadph[c] + h[c] <=> nChloramphenicol[c] + nadp[c] + h2o[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 3369435, PMID: 6625558, PMID: 26261284 |
| DB00446 |
Chloramphenicol |
Nchloramphenicol |
eNit |
Chloramphenicol Microbiota nitroreduction |
Chloramphenicol[e] + nadph[e] + h[e] <=> nChloramphenicol[e] + nadp[e] + h2o[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 3369435, PMID: 6625558, PMID: 26261284 |
| DB01050 |
S-Carboxy Ibuprofen Glucuronide |
S-Carboxy Ibuprofen |
UidAc |
S-carboxy ibuprofen beta-glucuronidase |
S-carboxy ibuprofen glucuronide[c] + h2o[c] -> S-carboxy ibuprofen[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01050 |
S-Carboxy Ibuprofen Glucuronide |
S-Carboxy Ibuprofen |
UidAe |
S-carboxy ibuprofen beta-glucuronidase extracellular |
S-carboxy ibuprofen glucuronide[e] + h2o[e] -> S-carboxy ibuprofen[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01050 |
S-Carboxy Ibuprofen Glucuronide |
S-Carboxy Ibuprofen |
UidAe |
S-carboxy ibuprofen beta-glucuronidase extracellular, periplasmatic |
S-carboxy ibuprofen glucuronide[p] + h2o[p] -> S-carboxy ibuprofen[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01050 |
S-Carboxy Ibuprofen |
S-Carboxy Ibuprofen |
UidABC |
Predicted glucuronide ABC transporter S-carboxy ibuprofen |
atp[c] + S-carboxy ibuprofen[e] + h2o[c] -> adp[c] + S-carboxy ibuprofen[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
S-Carboxy Ibuprofen |
S-Carboxy Ibuprofen |
UidP |
Transport of D-Glucuronate S-carboxy ibuprofen |
S-carboxy ibuprofen[e] -> S-carboxy ibuprofen[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
S-Carboxy Ibuprofen |
S-Carboxy Ibuprofen |
UidB |
Glucuronate transport in via proton symport S-carboxy ibuprofen |
S-carboxy ibuprofen[e] + h[e] -> S-carboxy ibuprofen[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
S-Carboxy Ibuprofen |
S-Carboxy Ibuprofen |
UidB |
beta-glucuronidase reaction product export,S-carboxy ibuprofen, periplasmatic |
S-carboxy ibuprofen[c] -> S-carboxy ibuprofen[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
S-Carboxy Ibuprofen |
S-Carboxy Ibuprofen |
n.a. |
S-carboxy ibuprofen diffusion extracellular to periplasm |
S-carboxy ibuprofen[e] <=> S-carboxy ibuprofen[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
S-Carboxy Ibuprofen Glucuronide |
S-Carboxy Ibuprofen Glucuronide |
n.a. |
Glucuronate transport in via proton symport (in),S-carboxy ibuprofen glucuronide, periplasmatic |
S-carboxy ibuprofen glucuronide[p] + h[p] -> S-carboxy ibuprofen glucuronide[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
S-Carboxy Ibuprofen Glucuronide |
S-Carboxy Ibuprofen Glucuronide |
n.a. |
beta-glucuronidase reaction product export S-carboxy ibuprofen glucuronide |
S-carboxy ibuprofen glucuronide[c] -> S-carboxy ibuprofen glucuronide[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
S-Carboxy Ibuprofen Glucuronide |
S-Carboxy Ibuprofen Glucuronide |
n.a. |
S-carboxy ibuprofen glucuronide diffusion extracellular to periplasm |
S-carboxy ibuprofen glucuronide[e] <=> S-carboxy ibuprofen glucuronide[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00564 |
Cbenzoate_Glc |
Cbenzoate |
UidAc |
Carbamazepine Glucuronide beta-glucuronidase |
cBenzoate_glc[c] + h2o[c] -> cBenzoate[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00564 |
Cbenzoate_Glc |
Cbenzoate |
UidAe |
Carbamazepine Glucuronide beta-glucuronidase extracellular |
cBenzoate_glc[e] + h2o[e] -> cBenzoate[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00564 |
Cbenzoate_Glc |
Cbenzoate_Glc |
UidABC |
Predicted glucuronide ABC transporter Carbamazepine Glucuronide |
atp[c] + cBenzoate_glc[e] + h2o[c] -> adp[c] + cBenzoate_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00564 |
Cbenzoate_Glc |
Cbenzoate_Glc |
UidP |
Transport of D-Glucuronate Carbamazepine Glucuronide |
cBenzoate_glc[e] -> cBenzoate_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00564 |
Cbenzoate_Glc |
Cbenzoate_Glc |
UidB |
Glucuronate transport in via proton symport Carbamazepine Glucuronide |
cBenzoate_glc[e] + h[e] -> cBenzoate_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00564 |
Cbenzoate |
Cbenzoate |
n.a. |
beta-glucuronidase reaction product export Carbamazepine |
cBenzoate[c] -> cBenzoate[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Cd6168_Glc |
Cd6168 |
UidAc |
CD6168 Glucuronide beta-glucuronidase |
CD6168_glc[c] + h2o[c] -> CD6168[c] + glcur[c] + 2 h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 35713221 |
| n.a. |
Cd6168_Glc |
Cd6168 |
UidAe |
CD6168 Glucuronide beta-glucuronidase extracellular |
CD6168_glc[e] + h2o[e] -> CD6168[e] + glcur[e] + 2 h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 35713221 |
| n.a. |
Cd6168_Glc |
Cd6168 |
UidAe |
CD6168 Glucuronide beta-glucuronidase extracellular, periplasmatic |
CD6168_glc[p] + h2o[p] -> CD6168[p] + glcur[p] + 2 h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 35713221 |
| n.a. |
Cd6168_Glc |
Cd6168_Glc |
UidABC |
Predicted glucuronide ABC transporter CD6168 Glucuronide |
atp[c] + CD6168_glc[e] + h2o[c] -> adp[c] + CD6168_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Cd6168_Glc |
Cd6168_Glc |
UidP |
Transport of D-Glucuronate CD6168 Glucuronide |
CD6168_glc[e] -> CD6168_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Cd6168_Glc |
Cd6168_Glc |
UidB |
Glucuronate transport in via proton symport CD6168 Glucuronide |
CD6168_glc[e] + h[e] -> CD6168_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Cd6168_Glc |
Cd6168_Glc |
UidB |
Glucuronate transport in via proton symport CD6168 Glucuronide, periplasmatic |
CD6168_glc[p] + h[p] -> CD6168_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Cd6168_Glc |
Cd6168_Glc |
n.a. |
CD6168 Glucuronide diffusion extracellular to periplasm |
CD6168_glc[e] <=> CD6168_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Cd6168 |
Cd6168 |
n.a. |
beta-glucuronidase reaction product export CD6168 |
CD6168[c] -> CD6168[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Cd6168 |
Cd6168 |
n.a. |
beta-glucuronidase reaction product export CD6168, periplasmatic |
CD6168[c] -> CD6168[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Cd6168 |
Cd6168 |
n.a. |
CD6168 diffusion extracellular to periplasm |
CD6168[e] <=> CD6168[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00446 |
Chloramphenicol_Glc |
Chloramphenicol |
UidAc |
Chloramphenicol 3-Glucuronide beta-glucuronidase |
Chloramphenicol_glc[c] + h2o[c] -> Chloramphenicol[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00446 |
Chloramphenicol_Glc |
Chloramphenicol |
UidAe |
Chloramphenicol 3-Glucuronide beta-glucuronidase extracellular |
Chloramphenicol_glc[e] + h2o[e] -> Chloramphenicol[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00446 |
Chloramphenicol_Glc |
Chloramphenicol |
UidAe |
Chloramphenicol 3-Glucuronide beta-glucuronidase extracellular, periplasmatic |
Chloramphenicol_glc[p] + h2o[p] -> Chloramphenicol[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00446 |
Chloramphenicol_Glc |
Chloramphenicol_Glc |
UidABC |
Predicted glucuronide ABC transporter Chloramphenicol 3-Glucuronide |
atp[c] + Chloramphenicol_glc[e] + h2o[c] -> adp[c] + Chloramphenicol_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00446 |
Chloramphenicol_Glc |
Chloramphenicol_Glc |
UidP |
Transport of D-Glucuronate Chloramphenicol 3-Glucuronide |
Chloramphenicol_glc[e] -> Chloramphenicol_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00446 |
Chloramphenicol_Glc |
Chloramphenicol_Glc |
UidB |
Glucuronate transport in via proton symport Chloramphenicol 3-Glucuronide |
Chloramphenicol_glc[e] + h[e] -> Chloramphenicol_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00446 |
Chloramphenicol_Glc |
Chloramphenicol_Glc |
UidB |
Glucuronate transport in via proton symport Chloramphenicol 3-Glucuronide, periplasmatic |
Chloramphenicol_glc[p] + h[p] -> Chloramphenicol_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00446 |
Chloramphenicol_Glc |
Chloramphenicol_Glc |
n.a. |
Chloramphenicol 3-Glucuronide diffusion extracellular to periplasm |
Chloramphenicol_glc[e] <=> Chloramphenicol_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00446 |
Chloramphenicol |
Chloramphenicol |
n.a. |
beta-glucuronidase reaction product export Chloramphenicol |
Chloramphenicol[c] -> Chloramphenicol[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00446 |
Chloramphenicol |
Chloramphenicol |
n.a. |
beta-glucuronidase reaction product export Chloramphenicol, periplasmatic |
Chloramphenicol[c] -> Chloramphenicol[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00446 |
Chloramphenicol |
Chloramphenicol |
n.a. |
Chloramphenicol diffusion extracellular to periplasm |
Chloramphenicol[e] <=> Chloramphenicol[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00482 |
Celecoxib_C_Glc |
Celecoxib_C |
UidAc |
Carboxycelecoxib Glucuronide beta-glucuronidase |
Celecoxib_c_glc[c] + h2o[c] -> Celecoxib_c[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00482 |
Celecoxib_C_Glc |
Celecoxib_C |
UidAe |
Carboxycelecoxib Glucuronide beta-glucuronidase extracellular |
Celecoxib_c_glc[e] + h2o[e] -> Celecoxib_c[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00482 |
Celecoxib_C_Glc |
Celecoxib_C |
UidAe |
Carboxycelecoxib Glucuronide beta-glucuronidase extracellular, periplasmatic |
Celecoxib_c_glc[p] + h2o[p] -> Celecoxib_c[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00482 |
Celecoxib_C_Glc |
Celecoxib_C_Glc |
UidABC |
Predicted glucuronide ABC transporter Carboxycelecoxib Glucuronide |
atp[c] + Celecoxib_c_glc[e] + h2o[c] -> adp[c] + Celecoxib_c_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00482 |
Celecoxib_C_Glc |
Celecoxib_C_Glc |
UidP |
Transport of D-Glucuronate Carboxycelecoxib Glucuronide |
Celecoxib_c_glc[e] -> Celecoxib_c_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00482 |
Celecoxib_C_Glc |
Celecoxib_C_Glc |
UidB |
Glucuronate transport in via proton symport Carboxycelecoxib Glucuronide |
Celecoxib_c_glc[e] + h[e] -> Celecoxib_c_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00482 |
Celecoxib_C_Glc |
Celecoxib_C_Glc |
UidB |
Glucuronate transport in via proton symport Carboxycelecoxib Glucuronide, periplasmatic |
Celecoxib_c_glc[p] + h[p] -> Celecoxib_c_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00482 |
Celecoxib_C_Glc |
Celecoxib_C_Glc |
n.a. |
Carboxycelecoxib Glucuronide diffusion extracellular to periplasm |
Celecoxib_c_glc[e] <=> Celecoxib_c_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00482 |
Celecoxib_C |
Celecoxib_C |
n.a. |
beta-glucuronidase reaction product export Carboxycelecoxib |
Celecoxib_c[c] -> Celecoxib_c[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00482 |
Celecoxib_C |
Celecoxib_C |
n.a. |
beta-glucuronidase reaction product export Carboxycelecoxib, periplasmatic |
Celecoxib_c[c] -> Celecoxib_c[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00482 |
Celecoxib_C |
Celecoxib_C |
n.a. |
Carboxycelecoxib diffusion extracellular to periplasm |
Celecoxib_c[e] <=> Celecoxib_c[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00482 |
Celecoxib_Glc |
Celecoxib |
UidAc |
Celecoxib Glucuronide beta-glucuronidase |
Celecoxib_glc[c] + h2o[c] -> Celecoxib[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00482 |
Celecoxib_Glc |
Celecoxib |
UidAe |
Celecoxib Glucuronide beta-glucuronidase extracellular |
Celecoxib_glc[e] + h2o[e] -> Celecoxib[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00482 |
Celecoxib_Glc |
Celecoxib |
UidAe |
Celecoxib Glucuronide beta-glucuronidase extracellular, periplasmatic |
Celecoxib_glc[p] + h2o[p] -> Celecoxib[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00482 |
Celecoxib_Glc |
Celecoxib_Glc |
UidABC |
Predicted glucuronide ABC transporter Celecoxib Glucuronide |
atp[c] + Celecoxib_glc[e] + h2o[c] -> adp[c] + Celecoxib_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00482 |
Celecoxib_Glc |
Celecoxib_Glc |
UidP |
Transport of D-Glucuronate Celecoxib Glucuronide |
Celecoxib_glc[e] -> Celecoxib_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00482 |
Celecoxib_Glc |
Celecoxib_Glc |
UidB |
Glucuronate transport in via proton symport Celecoxib Glucuronide |
Celecoxib_glc[e] + h[e] -> Celecoxib_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00482 |
Celecoxib_Glc |
Celecoxib_Glc |
UidB |
Glucuronate transport in via proton symport Celecoxib Glucuronide, periplasmatic |
Celecoxib_glc[p] + h[p] -> Celecoxib_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00482 |
Celecoxib_Glc |
Celecoxib_Glc |
n.a. |
Celecoxib Glucuronide diffusion extracellular to periplasm |
Celecoxib_glc[e] <=> Celecoxib_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00482 |
Celecoxib |
Celecoxib |
n.a. |
beta-glucuronidase reaction product export Celecoxib |
Celecoxib[c] -> Celecoxib[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00482 |
Celecoxib |
Celecoxib |
n.a. |
beta-glucuronidase reaction product export Celecoxib, periplasmatic |
Celecoxib[c] -> Celecoxib[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00482 |
Celecoxib |
Celecoxib |
n.a. |
Celecoxib diffusion extracellular to periplasm |
Celecoxib[e] <=> Celecoxib[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00758 |
Clopidogrel Carboxylic Acid |
Clopidogrel Carboxylic Acid |
n.a. |
beta-glucuronidase reaction product export Clopidogrel Carboxylic Acid |
Clopidogrel Carboxylic Acid[c] -> Clopidogrel Carboxylic Acid[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00758 |
Clopidogrel Carboxylic Acid |
Clopidogrel Carboxylic Acid |
n.a. |
beta-glucuronidase reaction product export Clopidogrel Carboxylic Acid, periplasmatic |
Clopidogrel Carboxylic Acid[c] -> Clopidogrel Carboxylic Acid[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00758 |
Clopidogrel Carboxylic Acid |
Clopidogrel Carboxylic Acid |
n.a. |
Clopidogrel Carboxylic Acid diffusion extracellular to periplasm |
Clopidogrel Carboxylic Acid[e] <=> Clopidogrel Carboxylic Acid[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00758 |
Clopidogrel Acyl-Beta-D-Glucuronide |
Clopidogrel Carboxylic Acid |
UidAc |
Clopidogrel Acyl-Beta-D-Glucuronide beta-glucuronidase |
Clopidogrel Acyl-Beta-D-Glucuronide[c] + h2o[c] -> Clopidogrel Carboxylic Acid[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00758 |
Clopidogrel Acyl-Beta-D-Glucuronide |
Clopidogrel Carboxylic Acid |
UidAe |
Clopidogrel Acyl-Beta-D-Glucuronide beta-glucuronidase extracellular |
Clopidogrel Acyl-Beta-D-Glucuronide[e] + h2o[e] -> Clopidogrel Carboxylic Acid[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00758 |
Clopidogrel Acyl-Beta-D-Glucuronide |
Clopidogrel Carboxylic Acid |
UidAe |
Clopidogrel Acyl-Beta-D-Glucuronide beta-glucuronidase extracellular, periplasmatic |
Clopidogrel Acyl-Beta-D-Glucuronide[p] + h2o[p] -> Clopidogrel Carboxylic Acid[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00758 |
Clopidogrel Acyl-Beta-D-Glucuronide |
Clopidogrel Acyl-Beta-D-Glucuronide |
UidABC |
Predicted glucuronide ABC transporter Clopidogrel Acyl-Beta-D-Glucuronide |
atp[c] + Clopidogrel Acyl-Beta-D-Glucuronide[e] + h2o[c] -> adp[c] + Clopidogrel Acyl-Beta-D-Glucuronide[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00758 |
Clopidogrel Acyl-Beta-D-Glucuronide |
Clopidogrel Acyl-Beta-D-Glucuronide |
UidP |
Transport of D-Glucuronate Clopidogrel Acyl-Beta-D-Glucuronide |
Clopidogrel Acyl-Beta-D-Glucuronide[e] -> Clopidogrel Acyl-Beta-D-Glucuronide[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00758 |
Clopidogrel Acyl-Beta-D-Glucuronide |
Clopidogrel Acyl-Beta-D-Glucuronide |
UidB |
Glucuronate transport in via proton symport Clopidogrel Acyl-Beta-D-Glucuronide |
Clopidogrel Acyl-Beta-D-Glucuronide[e] + h[e] -> Clopidogrel Acyl-Beta-D-Glucuronide[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00758 |
Clopidogrel Acyl-Beta-D-Glucuronide |
Clopidogrel Acyl-Beta-D-Glucuronide |
UidB |
Glucuronate transport in via proton symport Clopidogrel Acyl-Beta-D-Glucuronide, periplasmatic |
Clopidogrel Acyl-Beta-D-Glucuronide[p] + h[p] -> Clopidogrel Acyl-Beta-D-Glucuronide[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00758 |
Clopidogrel Acyl-Beta-D-Glucuronide |
Clopidogrel Acyl-Beta-D-Glucuronide |
n.a. |
Clopidogrel Acyl-Beta-D-Glucuronide diffusion extracellular to periplasm |
Clopidogrel Acyl-Beta-D-Glucuronide[e] <=> Clopidogrel Acyl-Beta-D-Glucuronide[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00439 |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1 |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1 |
n.a. |
beta-glucuronidase reaction product export cerivastatin-M1 |
cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1[c] -> cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00439 |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23 |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23 |
n.a. |
beta-glucuronidase reaction product export cerivastatin-M23 |
cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23[c] -> cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00439 |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1-Glucuronide |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1 |
UidAc |
cerivastatin-M1-glucuronide beta-glucuronidase |
cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1-glucuronide[c] + h2o[c] -> cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00439 |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1-Glucuronide |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1 |
UidAe |
cerivastatin-M1-glucuronide beta-glucuronidase extracellular |
cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1-glucuronide[e] + h2o[e] -> cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00439 |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1-Glucuronide |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1 |
UidAe |
cerivastatin-M1-glucuronide beta-glucuronidase extracellular, periplasmatic |
cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1-glucuronide[p] + h2o[p] -> cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00439 |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1-Glucuronide |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1-Glucuronide |
UidABC |
Predicted glucuronide ABC transporter cerivastatin-M1-glucuronide |
atp[c] + cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1-glucuronide[e] + h2o[c] -> adp[c] + cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1-glucuronide[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00439 |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1-Glucuronide |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1-Glucuronide |
UidP |
Transport of D-Glucuronate cerivastatin-M1-glucuronide |
cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1-glucuronide[e] -> cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1-glucuronide[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00439 |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1-Glucuronide |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1-Glucuronide |
UidB |
Glucuronate transport in via proton symport cerivastatin-M1-glucuronide |
cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1-glucuronide[e] + h[e] -> cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1-glucuronide[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00439 |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1-Glucuronide |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1-Glucuronide |
UidB |
Glucuronate transport in via proton symport cerivastatin-M1-glucuronide, periplasmatic |
cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1-glucuronide[p] + h[p] -> cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1-glucuronide[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00439 |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1-Glucuronide |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1-Glucuronide |
n.a. |
cerivastatin-M1-glucuronide diffusion extracellular to periplasm |
cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1-glucuronide[e] <=> cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1-glucuronide[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00439 |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23-Glucuronide |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23 |
UidAc |
cerivastatin-M23-glucuronide beta-glucuronidase |
cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23-glucuronide[c] + h2o[c] -> cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00439 |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23-Glucuronide |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23 |
UidAe |
cerivastatin-M23-glucuronide beta-glucuronidase extracellular |
cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23-glucuronide[e] + h2o[e] -> cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00439 |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23-Glucuronide |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23 |
UidAe |
cerivastatin-M23-glucuronide beta-glucuronidase extracellular, periplasmatic |
cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23-glucuronide[p] + h2o[p] -> cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00439 |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23-Glucuronide |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23-Glucuronide |
UidABC |
Predicted glucuronide ABC transporter cerivastatin-M23-glucuronide |
atp[c] + cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23-glucuronide[e] + h2o[c] -> adp[c] + cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23-glucuronide[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00439 |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23-Glucuronide |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23-Glucuronide |
UidP |
Transport of D-Glucuronate cerivastatin-M23-glucuronide |
cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23-glucuronide[e] -> cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23-glucuronide[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00439 |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23-Glucuronide |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23-Glucuronide |
UidB |
Glucuronate transport in via proton symport cerivastatin-M23-glucuronide |
cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23-glucuronide[e] + h[e] -> cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23-glucuronide[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00439 |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23-Glucuronide |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23-Glucuronide |
UidB |
Glucuronate transport in via proton symport cerivastatin-M23-glucuronide, periplasmatic |
cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23-glucuronide[p] + h[p] -> cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23-glucuronide[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00439 |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23-Glucuronide |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23-Glucuronide |
n.a. |
cerivastatin-M23-glucuronide diffusion extracellular to periplasm |
cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23-glucuronide[e] <=> cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23-glucuronide[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01068 |
Clonazepam |
7-Aminoclonazepam |
Nit |
Clonazepam Microbiota nitroreduction |
Clonazepam[c] + 3 nadph[c] + 3 h[c] <=> 7-Aminoclonazepam[c] + 3 nadp[c] + 2 h2o[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 26261284 |
| DB01068 |
Clonazepam |
7-Aminoclonazepam |
eNit |
Clonazepam Microbiota nitroreduction |
Clonazepam[e] + 3 nadph[e] + 3 h[c] <=> 7-Aminoclonazepam[e] + 3 nadp[e] + 2 h2o[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 26261284 |
| DB01118 |
Deaminated Amiodarone (M5)_Glc |
Deaminated Amiodarone (M5) |
UidAc |
Deaminated Amiodarone Glucuronide (M14) beta-glucuronidase |
Deaminated Amiodarone (M5)_glc[c] + h2o[c] -> Deaminated Amiodarone (M5)[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01118 |
Deaminated Amiodarone (M5)_Glc |
Deaminated Amiodarone (M5) |
UidAe |
Deaminated Amiodarone Glucuronide (M14) beta-glucuronidase extracellular |
Deaminated Amiodarone (M5)_glc[e] + h2o[e] -> Deaminated Amiodarone (M5)[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01118 |
Deaminated Amiodarone (M5)_Glc |
Deaminated Amiodarone (M5) |
UidAe |
Deaminated Amiodarone Glucuronide (M14) beta-glucuronidase extracellular, periplasmatic |
Deaminated Amiodarone (M5)_glc[p] + h2o[p] -> Deaminated Amiodarone (M5)[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01118 |
Deaminated Amiodarone (M5)_Glc |
Deaminated Amiodarone (M5)_Glc |
UidABC |
Predicted glucuronide ABC transporter Deaminated Amiodarone Glucuronide (M14) |
atp[c] + Deaminated Amiodarone (M5)_glc[e] + h2o[c] -> adp[c] + Deaminated Amiodarone (M5)_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
Deaminated Amiodarone (M5)_Glc |
Deaminated Amiodarone (M5)_Glc |
UidP |
Transport of D-Glucuronate Deaminated Amiodarone Glucuronide (M14) |
Deaminated Amiodarone (M5)_glc[e] -> Deaminated Amiodarone (M5)_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
Deaminated Amiodarone (M5)_Glc |
Deaminated Amiodarone (M5)_Glc |
UidB |
Glucuronate transport in via proton symport Deaminated Amiodarone Glucuronide (M14) |
Deaminated Amiodarone (M5)_glc[e] + h[e] -> Deaminated Amiodarone (M5)_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
Deaminated Amiodarone (M5)_Glc |
Deaminated Amiodarone (M5)_Glc |
UidB |
Glucuronate transport in via proton symport Deaminated Amiodarone Glucuronide (M14), periplasmatic |
Deaminated Amiodarone (M5)_glc[p] + h[p] -> Deaminated Amiodarone (M5)_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
Deaminated Amiodarone (M5)_Glc |
Deaminated Amiodarone (M5)_Glc |
n.a. |
Deaminated Amiodarone Glucuronide (M14) diffusion extracellular to periplasm |
Deaminated Amiodarone (M5)_glc[e] <=> Deaminated Amiodarone (M5)_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
Deaminated Amiodarone (M5) |
Deaminated Amiodarone (M5) |
n.a. |
beta-glucuronidase reaction product export Deaminated Amiodarone (M5) |
Deaminated Amiodarone (M5)[c] -> Deaminated Amiodarone (M5)[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
Deaminated Amiodarone (M5) |
Deaminated Amiodarone (M5) |
n.a. |
beta-glucuronidase reaction product export Deaminated Amiodarone (M5), periplasmatic |
Deaminated Amiodarone (M5)[c] -> Deaminated Amiodarone (M5)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
Deaminated Amiodarone (M5) |
Deaminated Amiodarone (M5) |
n.a. |
Deaminated Amiodarone (M5) diffusion extracellular to periplasm |
Deaminated Amiodarone (M5)[e] <=> Deaminated Amiodarone (M5)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00586 |
Diclofenac_Glc |
Diclofenac |
UidAc |
Diclofenac Acyl Glucuronide beta-glucuronidase |
Diclofenac_glc[c] + h2o[c] -> Diclofenac[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 23829165 |
| DB00586 |
Diclofenac_Glc |
Diclofenac |
UidAe |
Diclofenac Acyl Glucuronide beta-glucuronidase extracellular |
Diclofenac_glc[e] + h2o[e] -> Diclofenac[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 23829165 |
| DB00586 |
Diclofenac_Glc |
Diclofenac |
UidAe |
Diclofenac Acyl Glucuronide beta-glucuronidase extracellular, periplasmatic |
Diclofenac_glc[p] + h2o[p] -> Diclofenac[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00586 |
Diclofenac_Glc |
Diclofenac_Glc |
UidABC |
Predicted glucuronide ABC transporter Diclofenac Acyl Glucuronide |
atp[c] + Diclofenac_glc[e] + h2o[c] -> adp[c] + Diclofenac_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00586 |
Diclofenac_Glc |
Diclofenac_Glc |
UidP |
Transport of D-Glucuronate Diclofenac Acyl Glucuronide |
Diclofenac_glc[e] -> Diclofenac_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00586 |
Diclofenac_Glc |
Diclofenac_Glc |
UidB |
Glucuronate transport in via proton symport Diclofenac Acyl Glucuronide |
Diclofenac_glc[e] + h[e] -> Diclofenac_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00586 |
Diclofenac_Glc |
Diclofenac_Glc |
UidB |
Glucuronate transport in via proton symport Diclofenac Acyl Glucuronide, periplasmatic |
Diclofenac_glc[p] + h[p] -> Diclofenac_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00586 |
Diclofenac_Glc |
Diclofenac_Glc |
n.a. |
Diclofenac Acyl Glucuronide diffusion extracellular to periplasm |
Diclofenac_glc[e] <=> Diclofenac_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00586 |
Diclofenac |
Diclofenac |
n.a. |
beta-glucuronidase reaction product export Diclofenac |
Diclofenac[c] -> Diclofenac[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00586 |
Diclofenac |
Diclofenac |
n.a. |
beta-glucuronidase reaction product export Diclofenac, periplasmatic |
Diclofenac[c] -> Diclofenac[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00586 |
Diclofenac |
Diclofenac |
n.a. |
Diclofenac diffusion extracellular to periplasm |
Diclofenac[e] <=> Diclofenac[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
Di-N-Desethylamiodarone (Ddea) _Glc |
Di-N-Desethylamiodarone (Ddea) |
UidAc |
Di-N-Desethylamiodarone Glucuronide Conjugate (DDEA_Glc) beta-glucuronidase |
Di-N-Desethylamiodarone (DDEA) _glc[c] + h2o[c] -> Di-N-Desethylamiodarone (DDEA) [c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01118 |
Di-N-Desethylamiodarone (Ddea) _Glc |
Di-N-Desethylamiodarone (Ddea) |
UidAe |
Di-N-Desethylamiodarone Glucuronide Conjugate (DDEA_Glc) beta-glucuronidase extracellular |
Di-N-Desethylamiodarone (DDEA) _glc[e] + h2o[e] -> Di-N-Desethylamiodarone (DDEA) [e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01118 |
Di-N-Desethylamiodarone (Ddea) _Glc |
Di-N-Desethylamiodarone (Ddea) |
UidAe |
Di-N-Desethylamiodarone Glucuronide Conjugate (DDEA_Glc) beta-glucuronidase extracellular, periplasmatic |
Di-N-Desethylamiodarone (DDEA) _glc[p] + h2o[p] -> Di-N-Desethylamiodarone (DDEA) [p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01118 |
Di-N-Desethylamiodarone (Ddea) _Glc |
Di-N-Desethylamiodarone (Ddea) _Glc |
UidABC |
Predicted glucuronide ABC transporter Di-N-Desethylamiodarone Glucuronide Conjugate (DDEA_Glc) |
atp[c] + Di-N-Desethylamiodarone (DDEA) _glc[e] + h2o[c] -> adp[c] + Di-N-Desethylamiodarone (DDEA) _glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
Di-N-Desethylamiodarone (Ddea) _Glc |
Di-N-Desethylamiodarone (Ddea) _Glc |
UidP |
Transport of D-Glucuronate Di-N-Desethylamiodarone Glucuronide Conjugate (DDEA_Glc) |
Di-N-Desethylamiodarone (DDEA) _glc[e] -> Di-N-Desethylamiodarone (DDEA) _glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
Di-N-Desethylamiodarone (Ddea) _Glc |
Di-N-Desethylamiodarone (Ddea) _Glc |
UidB |
Glucuronate transport in via proton symport Di-N-Desethylamiodarone Glucuronide Conjugate (DDEA_Glc) |
Di-N-Desethylamiodarone (DDEA) _glc[e] + h[e] -> Di-N-Desethylamiodarone (DDEA) _glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
Di-N-Desethylamiodarone (Ddea) _Glc |
Di-N-Desethylamiodarone (Ddea) _Glc |
UidB |
Glucuronate transport in via proton symport Di-N-Desethylamiodarone Glucuronide Conjugate (DDEA_Glc), periplasmatic |
Di-N-Desethylamiodarone (DDEA) _glc[p] + h[p] -> Di-N-Desethylamiodarone (DDEA) _glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
Di-N-Desethylamiodarone (Ddea) _Glc |
Di-N-Desethylamiodarone (Ddea) _Glc |
n.a. |
Di-N-Desethylamiodarone Glucuronide Conjugate (DDEA_Glc) diffusion extracellular to periplasm |
Di-N-Desethylamiodarone (DDEA) _glc[e] <=> Di-N-Desethylamiodarone (DDEA) _glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
Di-N-Desethylamiodarone (Ddea) |
Di-N-Desethylamiodarone (Ddea) |
n.a. |
beta-glucuronidase reaction product export Di-N-Desethylamiodarone (DDEA) |
Di-N-Desethylamiodarone (DDEA) [c] -> Di-N-Desethylamiodarone (DDEA) [e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
Di-N-Desethylamiodarone (Ddea) |
Di-N-Desethylamiodarone (Ddea) |
n.a. |
beta-glucuronidase reaction product export Di-N-Desethylamiodarone (DDEA), periplasmatic |
Di-N-Desethylamiodarone (DDEA) [c] -> Di-N-Desethylamiodarone (DDEA) [p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
Di-N-Desethylamiodarone (Ddea) |
Di-N-Desethylamiodarone (Ddea) |
n.a. |
Di-N-Desethylamiodarone (DDEA) diffusion extracellular to periplasm |
Di-N-Desethylamiodarone (DDEA) [e] <=> Di-N-Desethylamiodarone (DDEA) [p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00637 |
Desmethylastemizole_Glc |
Desmethylastemizole |
UidAc |
Desmethylastemozole Glucuronide beta-glucuronidase |
Desmethylastemizole_glc[c] + h2o[c] -> Desmethylastemizole[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00637 |
Desmethylastemizole_Glc |
Desmethylastemizole |
UidAe |
Desmethylastemozole Glucuronide beta-glucuronidase extracellular |
Desmethylastemizole_glc[e] + h2o[e] -> Desmethylastemizole[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00637 |
Desmethylastemizole_Glc |
Desmethylastemizole |
UidAe |
Desmethylastemozole Glucuronide beta-glucuronidase extracellular, periplasmatic |
Desmethylastemizole_glc[p] + h2o[p] -> Desmethylastemizole[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00637 |
Desmethylastemizole_Glc |
Desmethylastemizole_Glc |
UidABC |
Predicted glucuronide ABC transporter Desmethylastemozole Glucuronide |
atp[c] + Desmethylastemizole_glc[e] + h2o[c] -> adp[c] + Desmethylastemizole_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00637 |
Desmethylastemizole_Glc |
Desmethylastemizole_Glc |
UidP |
Transport of D-Glucuronate Desmethylastemozole Glucuronide |
Desmethylastemizole_glc[e] -> Desmethylastemizole_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00637 |
Desmethylastemizole_Glc |
Desmethylastemizole_Glc |
UidB |
Glucuronate transport in via proton symport Desmethylastemozole Glucuronide |
Desmethylastemizole_glc[e] + h[e] -> Desmethylastemizole_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00637 |
Desmethylastemizole_Glc |
Desmethylastemizole_Glc |
UidB |
Glucuronate transport in via proton symport Desmethylastemozole Glucuronide, periplasmatic |
Desmethylastemizole_glc[p] + h[p] -> Desmethylastemizole_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00637 |
Desmethylastemizole_Glc |
Desmethylastemizole_Glc |
n.a. |
Desmethylastemozole Glucuronide diffusion extracellular to periplasm |
Desmethylastemizole_glc[e] <=> Desmethylastemizole_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00637 |
Desmethylastemizole |
Desmethylastemizole |
n.a. |
beta-glucuronidase reaction product export Desmethylastemizole |
Desmethylastemizole[c] -> Desmethylastemizole[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00637 |
Desmethylastemizole |
Desmethylastemizole |
n.a. |
beta-glucuronidase reaction product export Desmethylastemizole, periplasmatic |
Desmethylastemizole[c] -> Desmethylastemizole[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00637 |
Desmethylastemizole |
Desmethylastemizole |
n.a. |
Desmethylastemizole diffusion extracellular to periplasm |
Desmethylastemizole[e] <=> Desmethylastemizole[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00441 |
Gemci1,2,4-Triaminobenzeneine (2',2'-Difluorodeoxycytidine) |
Gemci1,2,4-Triaminobenzeneine (2',2'-Difluorodeoxycytidine) |
CdaABC |
Gemcitabine (2',2'-difluorodeoxycytidine) Purine nucleoside ABC transporter |
Gemci1,2,4-Triaminobenzeneine (2',2'-difluorodeoxycytidine)[e] + atp[c] + h2o[c] -> adp[c] + Gemci1,2,4-Triaminobenzeneine (2',2'-difluorodeoxycytidine)[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00441 |
Gemci1,2,4-Triaminobenzeneine (2',2'-Difluorodeoxycytidine) |
Gemci1,2,4-Triaminobenzeneine (2',2'-Difluorodeoxycytidine) |
CdaABC |
Gemcitabine (2,2-difluorodeoxycytidine) Purine nucleoside ABC transporter, periplasmatic |
atp[c] + h2o[c] + Gemci1,2,4-Triaminobenzeneine (2',2'-difluorodeoxycytidine)[p] -> adp[c] + Gemci1,2,4-Triaminobenzeneine (2',2'-difluorodeoxycytidine)[c] + h[c] + pi[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00441 |
Gemci1,2,4-Triaminobenzeneine (2',2'-Difluorodeoxycytidine) |
2',2'-Difluorodeoxyuridine |
Cda |
Cytidine Deaminase (Gemcitabine) |
Gemci1,2,4-Triaminobenzeneine (2',2'-difluorodeoxycytidine)[c] + h[c] + h2o[c] -> nh4[c] + 2',2'-Difluorodeoxyuridine[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 26261286 |
| DB00441 |
Gemci1,2,4-Triaminobenzeneine (2',2'-Difluorodeoxycytidine) |
2',2'-Difluorodeoxyuridine |
eCda |
Cytidine Deaminase (Gemcitabine) |
Gemci1,2,4-Triaminobenzeneine (2',2'-difluorodeoxycytidine)[e] + h[e] + h2o[e] -> nh4[e] + 2',2'-Difluorodeoxyuridine[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 26261286 |
| DB00441 |
Gemci1,2,4-Triaminobenzeneine (2',2'-Difluorodeoxycytidine) |
2',2'-Difluorodeoxyuridine |
eCda |
Cytidine Deaminase (Gemcitabine), periplasmatic |
Gemci1,2,4-Triaminobenzeneine (2',2'-difluorodeoxycytidine)[p] + h2o[p] + h[p] -> 2',2'-Difluorodeoxyuridine[p] + nh4[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00441 |
Gemci1,2,4-Triaminobenzeneine (2',2'-Difluorodeoxycytidine) |
Gemci1,2,4-Triaminobenzeneine (2',2'-Difluorodeoxycytidine) |
n.a. |
Gemcitabine diffusion extracellular to periplasm |
Gemci1,2,4-Triaminobenzeneine (2',2'-difluorodeoxycytidine)[e] <=> Gemci1,2,4-Triaminobenzeneine (2',2'-difluorodeoxycytidine)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB02745 |
2',2'-Difluorodeoxyuridine |
2',2'-Difluorodeoxyuridine |
CdaABC |
2,2-Difluorodeoxyuridine export |
2',2'-Difluorodeoxyuridine[c] -> 2',2'-Difluorodeoxyuridine[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB02745 |
2',2'-Difluorodeoxyuridine |
2',2'-Difluorodeoxyuridine |
CdaABC |
2,2-Difluorodeoxyuridine export, periplasmatic |
2',2'-Difluorodeoxyuridine[c] -> 2',2'-Difluorodeoxyuridine[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB02745 |
2',2'-Difluorodeoxyuridine |
2',2'-Difluorodeoxyuridine |
n.a. |
2,2-Difluorodeoxyuridine diffusion extracellular to periplasm |
2',2'-Difluorodeoxyuridine[e] <=> 2',2'-Difluorodeoxyuridine[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Glycinecochenodeoxycholate |
Glycinecochenodeoxycholate |
n.a. |
glycochenodeoxycholate diffusion extracellular to periplasm |
Glycinecochenodeoxycholate[e] <=> Glycinecochenodeoxycholate[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB03419 |
Dh5-Fluorouracil |
Dh5-Fluorouracil |
CodB |
5,6-Dihydro 5-Fluoro Uracil Transport via Faciliated Diffusion |
dh5-Fluorouracil[e] <=> dh5-Fluorouracil[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01396 |
Digitoxin |
Digitoxin |
Cgr |
Digitoxin transport in via proton symport reversible |
Digitoxin[e] + h[e] <=> Digitoxin[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01396 |
Digoxin_Glc |
Digoxin |
UidAc |
Digoxin 16-Glucuronide beta-glucuronidase |
Digoxin_glc[c] + h2o[c] -> Digoxin[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01396 |
Digoxin_Glc |
Digoxin |
UidAe |
Digoxin 16-Glucuronide beta-glucuronidase extracellular |
Digoxin_glc[e] + h2o[e] -> Digoxin[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01396 |
Digoxin_Glc |
Digoxin |
UidAe |
Digoxin 16-Glucuronide beta-glucuronidase extracellular, periplasmatic |
Digoxin_glc[p] + h2o[p] -> Digoxin[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01396 |
Digoxin_Glc |
Digoxin_Glc |
UidABC |
Predicted glucuronide ABC transporter Digoxin 16-Glucuronide |
atp[c] + Digoxin_glc[e] + h2o[c] -> adp[c] + Digoxin_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01396 |
Digoxin_Glc |
Digoxin_Glc |
UidP |
Transport of D-Glucuronate Digoxin 16-Glucuronide |
Digoxin_glc[e] -> Digoxin_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01396 |
Digoxin_Glc |
Digoxin_Glc |
UidB |
Glucuronate transport in via proton symport Digoxin 16-Glucuronide |
Digoxin_glc[e] + h[e] -> Digoxin_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01396 |
Digoxin_Glc |
Digoxin_Glc |
UidB |
Glucuronate transport in via proton symport Digoxin 16-Glucuronide, periplasmatic |
Digoxin_glc[p] + h[p] -> Digoxin_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01396 |
Digoxin_Glc |
Digoxin_Glc |
n.a. |
Digoxin 16-Glucuronide diffusion extracellular to periplasm |
Digoxin_glc[e] <=> Digoxin_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01396 |
Digoxin |
Digoxin |
Cgr |
Digoxin transport in via proton symport reversible |
Digoxin[e] + h[e] <=> Digoxin[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01396 |
Digoxin |
Digoxin |
n.a. |
beta-glucuronidase reaction product export Digoxin |
Digoxin[c] -> Digoxin[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01396 |
Digoxin |
Digoxin |
n.a. |
beta-glucuronidase reaction product export Digoxin, periplasmatic |
Digoxin[c] -> Digoxin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01396 |
Digoxin |
Digoxin |
n.a. |
Digoxin diffusion extracellular to periplasm |
Digoxin[e] <=> Digoxin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01396 |
Digitoxin |
Dihydro_Digitoxin |
Cgr |
Digitoxin reduction |
Digitoxin[c] + nadh[c] + h[c] <=> dihydro_Digitoxin[c] + nad[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 971699 |
| DB01396 |
Dihydro_Digitoxin |
Dihydro_Digitoxin |
Cgr |
20,22-Dihydrodigitoxin transport in via proton symport reversible |
dihydro_Digitoxin[e] + h[e] <=> dihydro_Digitoxin[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01396 |
Digoxin |
Dihydro_Digoxin |
Cgr |
Digitoxin reduction |
Digoxin[c] + nadh[c] + 2 h[c] <=> dihydro_Digoxin[c] + nad[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 971699 |
| DB00390 |
Dihydro_Digoxin |
Dihydro_Digoxin |
Cgr |
Dihydrodigoxin transport in via proton symport reversible |
dihydro_Digoxin[e] + h[e] <=> dihydro_Digoxin[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB14850 |
Deleobuvir_Glc |
Deleobuvir |
UidAc |
Deleobuvir Glucuronide beta-glucuronidase |
Deleobuvir_glc[c] + h2o[c] -> Deleobuvir[c] + glcur[c] + 2 h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB14850 |
Deleobuvir_Glc |
Deleobuvir |
UidAe |
Deleobuvir Glucuronide beta-glucuronidase extracellular |
Deleobuvir_glc[e] + h2o[e] -> Deleobuvir[e] + glcur[e] + 2 h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB14850 |
Deleobuvir_Glc |
Deleobuvir |
UidAe |
Deleobuvir Glucuronide beta-glucuronidase extracellular, periplasmatic |
Deleobuvir_glc[p] + h2o[p] -> Deleobuvir[p] + glcur[p] + 2 h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB14850 |
Deleobuvir_Glc |
Deleobuvir_Glc |
UidABC |
Predicted glucuronide ABC transporter Deleobuvir Glucuronide |
atp[c] + Deleobuvir_glc[e] + h2o[c] -> adp[c] + Deleobuvir_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB14850 |
Deleobuvir_Glc |
Deleobuvir_Glc |
UidP |
Transport of D-Glucuronate Deleobuvir Glucuronide |
Deleobuvir_glc[e] -> Deleobuvir_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB14850 |
Deleobuvir_Glc |
Deleobuvir_Glc |
UidB |
Glucuronate transport in via proton symport Deleobuvir Glucuronide |
Deleobuvir_glc[e] + h[e] -> Deleobuvir_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB14850 |
Deleobuvir_Glc |
Deleobuvir_Glc |
UidB |
Glucuronate transport in via proton symport Deleobuvir Glucuronide, periplasmatic |
Deleobuvir_glc[p] + h[p] -> Deleobuvir_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB14850 |
Deleobuvir_Glc |
Deleobuvir_Glc |
n.a. |
Deleobuvir Glucuronide diffusion extracellular to periplasm |
Deleobuvir_glc[e] <=> Deleobuvir_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB14850 |
Deleobuvir |
Deleobuvir |
n.a. |
beta-glucuronidase reaction product export Deleobuvir |
Deleobuvir[c] -> Deleobuvir[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB14850 |
Deleobuvir |
Deleobuvir |
n.a. |
beta-glucuronidase reaction product export Deleobuvir, periplasmatic |
Deleobuvir[c] -> Deleobuvir[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB14850 |
Deleobuvir |
Deleobuvir |
n.a. |
Deleobuvir diffusion extracellular to periplasm |
Deleobuvir[e] <=> Deleobuvir[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
5-O-Desmethyl Donepezil |
5-O-Desmethyl Donepezil |
n.a. |
beta-glucuronidase reaction product export 5-O-Desmethyl Donepezil |
5-O-Desmethyl Donepezil[c] -> 5-O-Desmethyl Donepezil[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
5-O-Desmethyl Donepezil |
5-O-Desmethyl Donepezil |
n.a. |
beta-glucuronidase reaction product export 5-O-Desmethyl Donepezil, periplasmatic |
5-O-Desmethyl Donepezil[c] -> 5-O-Desmethyl Donepezil[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
5-O-Desmethyl Donepezil |
5-O-Desmethyl Donepezil |
n.a. |
5-O-Desmethyl Donepezil diffusion extracellular to periplasm |
5-O-Desmethyl Donepezil[e] <=> 5-O-Desmethyl Donepezil[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
6-O-Desmethyldonepezil |
6-O-Desmethyldonepezil |
n.a. |
beta-glucuronidase reaction product export 6-O-Desmethyldonepezil |
6-O-Desmethyldonepezil[c] -> 6-O-Desmethyldonepezil[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
6-O-Desmethyldonepezil |
6-O-Desmethyldonepezil |
n.a. |
beta-glucuronidase reaction product export 6-O-Desmethyldonepezil, periplasmatic |
6-O-Desmethyldonepezil[c] -> 6-O-Desmethyldonepezil[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
6-O-Desmethyldonepezil |
6-O-Desmethyldonepezil |
n.a. |
6-O-Desmethyldonepezil diffusion extracellular to periplasm |
6-O-Desmethyldonepezil[e] <=> 6-O-Desmethyldonepezil[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M11 |
6-O-Desmethyldonepezil |
UidAc |
Donepezil Metabolite M11 beta-glucuronidase |
Donepezil Me1,2,4-Triaminobenzeneolite M11[c] + h2o[c] -> 6-O-Desmethyldonepezil[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M11 |
6-O-Desmethyldonepezil |
UidAe |
Donepezil Metabolite M11 beta-glucuronidase extracellular |
Donepezil Me1,2,4-Triaminobenzeneolite M11[e] + h2o[e] -> 6-O-Desmethyldonepezil[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M11 |
6-O-Desmethyldonepezil |
UidAe |
Donepezil Metabolite M11 beta-glucuronidase extracellular, periplasmatic |
Donepezil Me1,2,4-Triaminobenzeneolite M11[p] + h2o[p] -> 6-O-Desmethyldonepezil[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M11 |
Donepezil Me1,2,4-Triaminobenzeneolite M11 |
UidABC |
Predicted glucuronide ABC transporter Donepezil Metabolite M11 |
atp[c] + Donepezil Me1,2,4-Triaminobenzeneolite M11[e] + h2o[c] -> adp[c] + Donepezil Me1,2,4-Triaminobenzeneolite M11[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M11 |
Donepezil Me1,2,4-Triaminobenzeneolite M11 |
UidP |
Transport of D-Glucuronate Donepezil Metabolite M11 |
Donepezil Me1,2,4-Triaminobenzeneolite M11[e] -> Donepezil Me1,2,4-Triaminobenzeneolite M11[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M11 |
Donepezil Me1,2,4-Triaminobenzeneolite M11 |
UidB |
Glucuronate transport in via proton symport Donepezil Metabolite M11 |
Donepezil Me1,2,4-Triaminobenzeneolite M11[e] + h[e] -> Donepezil Me1,2,4-Triaminobenzeneolite M11[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M11 |
Donepezil Me1,2,4-Triaminobenzeneolite M11 |
UidB |
Glucuronate transport in via proton symport Donepezil Metabolite M11, periplasmatic |
Donepezil Me1,2,4-Triaminobenzeneolite M11[p] + h[p] -> Donepezil Me1,2,4-Triaminobenzeneolite M11[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M11 |
Donepezil Me1,2,4-Triaminobenzeneolite M11 |
n.a. |
Donepezil Metabolite M11 diffusion extracellular to periplasm |
Donepezil Me1,2,4-Triaminobenzeneolite M11[e] <=> Donepezil Me1,2,4-Triaminobenzeneolite M11[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M12 |
5-O-Desmethyl Donepezil |
UidAc |
Donepezil Metabolite M12 beta-glucuronidase |
Donepezil Me1,2,4-Triaminobenzeneolite M12[c] + h2o[c] -> 5-O-Desmethyl Donepezil[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M12 |
5-O-Desmethyl Donepezil |
UidAe |
Donepezil Metabolite M12 beta-glucuronidase extracellular |
Donepezil Me1,2,4-Triaminobenzeneolite M12[e] + h2o[e] -> 5-O-Desmethyl Donepezil[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M12 |
5-O-Desmethyl Donepezil |
UidAe |
Donepezil Metabolite M12 beta-glucuronidase extracellular, periplasmatic |
Donepezil Me1,2,4-Triaminobenzeneolite M12[p] + h2o[p] -> 5-O-Desmethyl Donepezil[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M12 |
Donepezil Me1,2,4-Triaminobenzeneolite M12 |
UidABC |
Predicted glucuronide ABC transporter Donepezil Metabolite M12 |
atp[c] + Donepezil Me1,2,4-Triaminobenzeneolite M12[e] + h2o[c] -> adp[c] + Donepezil Me1,2,4-Triaminobenzeneolite M12[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M12 |
Donepezil Me1,2,4-Triaminobenzeneolite M12 |
UidP |
Transport of D-Glucuronate Donepezil Metabolite M12 |
Donepezil Me1,2,4-Triaminobenzeneolite M12[e] -> Donepezil Me1,2,4-Triaminobenzeneolite M12[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M12 |
Donepezil Me1,2,4-Triaminobenzeneolite M12 |
UidB |
Glucuronate transport in via proton symport Donepezil Metabolite M12 |
Donepezil Me1,2,4-Triaminobenzeneolite M12[e] + h[e] -> Donepezil Me1,2,4-Triaminobenzeneolite M12[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M12 |
Donepezil Me1,2,4-Triaminobenzeneolite M12 |
UidB |
Glucuronate transport in via proton symport Donepezil Metabolite M12, periplasmatic |
Donepezil Me1,2,4-Triaminobenzeneolite M12[p] + h[p] -> Donepezil Me1,2,4-Triaminobenzeneolite M12[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M12 |
Donepezil Me1,2,4-Triaminobenzeneolite M12 |
n.a. |
Donepezil Metabolite M12 diffusion extracellular to periplasm |
Donepezil Me1,2,4-Triaminobenzeneolite M12[e] <=> Donepezil Me1,2,4-Triaminobenzeneolite M12[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M13 |
Donepezil Me1,2,4-Triaminobenzeneolite M9 |
UidAc |
Donepezil Metabolite M13 beta-glucuronidase |
Donepezil Me1,2,4-Triaminobenzeneolite M13[c] + h2o[c] -> Donepezil Me1,2,4-Triaminobenzeneolite M9[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M13 |
Donepezil Me1,2,4-Triaminobenzeneolite M9 |
UidAe |
Donepezil Metabolite M13 beta-glucuronidase extracellular |
Donepezil Me1,2,4-Triaminobenzeneolite M13[e] + h2o[e] -> Donepezil Me1,2,4-Triaminobenzeneolite M9[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M13 |
Donepezil Me1,2,4-Triaminobenzeneolite M9 |
UidAe |
Donepezil Metabolite M13 beta-glucuronidase extracellular, periplasmatic |
Donepezil Me1,2,4-Triaminobenzeneolite M13[p] + h2o[p] -> Donepezil Me1,2,4-Triaminobenzeneolite M9[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M13 |
Donepezil Me1,2,4-Triaminobenzeneolite M13 |
UidABC |
Predicted glucuronide ABC transporter Donepezil Metabolite M13 |
atp[c] + Donepezil Me1,2,4-Triaminobenzeneolite M13[e] + h2o[c] -> adp[c] + Donepezil Me1,2,4-Triaminobenzeneolite M13[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M13 |
Donepezil Me1,2,4-Triaminobenzeneolite M13 |
UidP |
Transport of D-Glucuronate Donepezil Metabolite M13 |
Donepezil Me1,2,4-Triaminobenzeneolite M13[e] -> Donepezil Me1,2,4-Triaminobenzeneolite M13[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M13 |
Donepezil Me1,2,4-Triaminobenzeneolite M13 |
UidB |
Glucuronate transport in via proton symport Donepezil Metabolite M13 |
Donepezil Me1,2,4-Triaminobenzeneolite M13[e] + h[e] -> Donepezil Me1,2,4-Triaminobenzeneolite M13[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M13 |
Donepezil Me1,2,4-Triaminobenzeneolite M13 |
UidB |
Glucuronate transport in via proton symport Donepezil Metabolite M13, periplasmatic |
Donepezil Me1,2,4-Triaminobenzeneolite M13[p] + h[p] -> Donepezil Me1,2,4-Triaminobenzeneolite M13[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M13 |
Donepezil Me1,2,4-Triaminobenzeneolite M13 |
n.a. |
Donepezil Metabolite M13 diffusion extracellular to periplasm |
Donepezil Me1,2,4-Triaminobenzeneolite M13[e] <=> Donepezil Me1,2,4-Triaminobenzeneolite M13[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M14 |
Donepezil Me1,2,4-Triaminobenzeneolite M9 |
UidAc |
Donepezil Metabolite M14 beta-glucuronidase |
Donepezil Me1,2,4-Triaminobenzeneolite M14[c] + h2o[c] -> Donepezil Me1,2,4-Triaminobenzeneolite M9[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M14 |
Donepezil Me1,2,4-Triaminobenzeneolite M9 |
UidAe |
Donepezil Metabolite M14 beta-glucuronidase extracellular |
Donepezil Me1,2,4-Triaminobenzeneolite M14[e] + h2o[e] -> Donepezil Me1,2,4-Triaminobenzeneolite M9[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M14 |
Donepezil Me1,2,4-Triaminobenzeneolite M9 |
UidAe |
Donepezil Metabolite M14 beta-glucuronidase extracellular, periplasmatic |
Donepezil Me1,2,4-Triaminobenzeneolite M14[p] + h2o[p] -> Donepezil Me1,2,4-Triaminobenzeneolite M9[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M14 |
Donepezil Me1,2,4-Triaminobenzeneolite M14 |
UidABC |
Predicted glucuronide ABC transporter Donepezil Metabolite M14 |
atp[c] + Donepezil Me1,2,4-Triaminobenzeneolite M14[e] + h2o[c] -> adp[c] + Donepezil Me1,2,4-Triaminobenzeneolite M14[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M14 |
Donepezil Me1,2,4-Triaminobenzeneolite M14 |
UidP |
Transport of D-Glucuronate Donepezil Metabolite M14 |
Donepezil Me1,2,4-Triaminobenzeneolite M14[e] -> Donepezil Me1,2,4-Triaminobenzeneolite M14[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M14 |
Donepezil Me1,2,4-Triaminobenzeneolite M14 |
UidB |
Glucuronate transport in via proton symport Donepezil Metabolite M14 |
Donepezil Me1,2,4-Triaminobenzeneolite M14[e] + h[e] -> Donepezil Me1,2,4-Triaminobenzeneolite M14[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M14 |
Donepezil Me1,2,4-Triaminobenzeneolite M14 |
UidB |
Glucuronate transport in via proton symport Donepezil Metabolite M14, periplasmatic |
Donepezil Me1,2,4-Triaminobenzeneolite M14[p] + h[p] -> Donepezil Me1,2,4-Triaminobenzeneolite M14[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M14 |
Donepezil Me1,2,4-Triaminobenzeneolite M14 |
n.a. |
Donepezil Metabolite M14 diffusion extracellular to periplasm |
Donepezil Me1,2,4-Triaminobenzeneolite M14[e] <=> Donepezil Me1,2,4-Triaminobenzeneolite M14[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M9 |
Donepezil Me1,2,4-Triaminobenzeneolite M9 |
n.a. |
beta-glucuronidase reaction product export Donepezil Metabolite M9 |
Donepezil Me1,2,4-Triaminobenzeneolite M9[c] -> Donepezil Me1,2,4-Triaminobenzeneolite M9[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M9 |
Donepezil Me1,2,4-Triaminobenzeneolite M9 |
n.a. |
beta-glucuronidase reaction product export Donepezil Metabolite M9, periplasmatic |
Donepezil Me1,2,4-Triaminobenzeneolite M9[c] -> Donepezil Me1,2,4-Triaminobenzeneolite M9[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M9 |
Donepezil Me1,2,4-Triaminobenzeneolite M9 |
n.a. |
Donepezil Metabolite M9 diffusion extracellular to periplasm |
Donepezil Me1,2,4-Triaminobenzeneolite M9[e] <=> Donepezil Me1,2,4-Triaminobenzeneolite M9[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB06414 |
Etravarine Dihydroxylated (M4, M5, M6)_Glc |
Etravarine Dihydroxylated (M4, M5, M6) |
UidAc |
Etravarine Dihydroxylated Glucuronide beta-glucuronidase |
Etravarine Dihydroxylated (M4, M5, M6)_glc[c] + h2o[c] -> Etravarine Dihydroxylated (M4, M5, M6)[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB06414 |
Etravarine Dihydroxylated (M4, M5, M6)_Glc |
Etravarine Dihydroxylated (M4, M5, M6) |
UidAe |
Etravarine Dihydroxylated Glucuronide beta-glucuronidase extracellular |
Etravarine Dihydroxylated (M4, M5, M6)_glc[e] + h2o[e] -> Etravarine Dihydroxylated (M4, M5, M6)[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB06414 |
Etravarine Dihydroxylated (M4, M5, M6)_Glc |
Etravarine Dihydroxylated (M4, M5, M6) |
UidAe |
Etravarine Dihydroxylated Glucuronide beta-glucuronidase extracellular, periplasmatic |
Etravarine Dihydroxylated (M4, M5, M6)_glc[p] + h2o[p] -> Etravarine Dihydroxylated (M4, M5, M6)[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB06414 |
Etravarine Dihydroxylated (M4, M5, M6)_Glc |
Etravarine Dihydroxylated (M4, M5, M6)_Glc |
UidABC |
Predicted glucuronide ABC transporter Etravarine Dihydroxylated Glucuronide |
atp[c] + Etravarine Dihydroxylated (M4, M5, M6)_glc[e] + h2o[c] -> adp[c] + Etravarine Dihydroxylated (M4, M5, M6)_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB06414 |
Etravarine Dihydroxylated (M4, M5, M6)_Glc |
Etravarine Dihydroxylated (M4, M5, M6)_Glc |
UidP |
Transport of D-Glucuronate Etravarine Dihydroxylated Glucuronide |
Etravarine Dihydroxylated (M4, M5, M6)_glc[e] -> Etravarine Dihydroxylated (M4, M5, M6)_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB06414 |
Etravarine Dihydroxylated (M4, M5, M6)_Glc |
Etravarine Dihydroxylated (M4, M5, M6)_Glc |
UidB |
Glucuronate transport in via proton symport Etravarine Dihydroxylated Glucuronide |
Etravarine Dihydroxylated (M4, M5, M6)_glc[e] + h[e] -> Etravarine Dihydroxylated (M4, M5, M6)_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB06414 |
Etravarine Dihydroxylated (M4, M5, M6)_Glc |
Etravarine Dihydroxylated (M4, M5, M6)_Glc |
UidB |
Glucuronate transport in via proton symport Etravarine Dihydroxylated Glucuronide, periplasmatic |
Etravarine Dihydroxylated (M4, M5, M6)_glc[p] + h[p] -> Etravarine Dihydroxylated (M4, M5, M6)_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB06414 |
Etravarine Dihydroxylated (M4, M5, M6)_Glc |
Etravarine Dihydroxylated (M4, M5, M6)_Glc |
n.a. |
Etravarine Dihydroxylated Glucuronide diffusion extracellular to periplasm |
Etravarine Dihydroxylated (M4, M5, M6)_glc[e] <=> Etravarine Dihydroxylated (M4, M5, M6)_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB06414 |
Etravarine Dihydroxylated (M4, M5, M6) |
Etravarine Dihydroxylated (M4, M5, M6) |
n.a. |
beta-glucuronidase reaction product export Etravarine Dihydroxylated (M4 M5 M6) |
Etravarine Dihydroxylated (M4, M5, M6)[c] -> Etravarine Dihydroxylated (M4, M5, M6)[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB06414 |
Etravarine Dihydroxylated (M4, M5, M6) |
Etravarine Dihydroxylated (M4, M5, M6) |
n.a. |
beta-glucuronidase reaction product export Etravarine Dihydroxylated (M4 M5 M6), periplasmatic |
Etravarine Dihydroxylated (M4, M5, M6)[c] -> Etravarine Dihydroxylated (M4, M5, M6)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB06414 |
Etravarine Dihydroxylated (M4, M5, M6) |
Etravarine Dihydroxylated (M4, M5, M6) |
n.a. |
Etravarine Dihydroxylated (M4, M5, M6) diffusion extracellular to periplasm |
Etravarine Dihydroxylated (M4, M5, M6)[e] <=> Etravarine Dihydroxylated (M4, M5, M6)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00582 |
Dihydroxyvoriconazole_Glc |
Dihydroxyvoriconazole |
UidAc |
Dihydroxyvoriconazole Glucuronide beta-glucuronidase |
Dihydroxyvoriconazole_glc[c] + h2o[c] -> Dihydroxyvoriconazole[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00582 |
Dihydroxyvoriconazole_Glc |
Dihydroxyvoriconazole |
UidAe |
Dihydroxyvoriconazole Glucuronide beta-glucuronidase extracellular |
Dihydroxyvoriconazole_glc[e] + h2o[e] -> Dihydroxyvoriconazole[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00582 |
Dihydroxyvoriconazole_Glc |
Dihydroxyvoriconazole |
UidAe |
Dihydroxyvoriconazole Glucuronide beta-glucuronidase extracellular, periplasmatic |
Dihydroxyvoriconazole_glc[p] + h2o[p] -> Dihydroxyvoriconazole[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00582 |
Dihydroxyvoriconazole_Glc |
Dihydroxyvoriconazole_Glc |
UidABC |
Predicted glucuronide ABC transporter Dihydroxyvoriconazole Glucuronide |
atp[c] + Dihydroxyvoriconazole_glc[e] + h2o[c] -> adp[c] + Dihydroxyvoriconazole_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00582 |
Dihydroxyvoriconazole_Glc |
Dihydroxyvoriconazole_Glc |
UidP |
Transport of D-Glucuronate Dihydroxyvoriconazole Glucuronide |
Dihydroxyvoriconazole_glc[e] -> Dihydroxyvoriconazole_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00582 |
Dihydroxyvoriconazole_Glc |
Dihydroxyvoriconazole_Glc |
UidB |
Glucuronate transport in via proton symport Dihydroxyvoriconazole Glucuronide |
Dihydroxyvoriconazole_glc[e] + h[e] -> Dihydroxyvoriconazole_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00582 |
Dihydroxyvoriconazole_Glc |
Dihydroxyvoriconazole_Glc |
UidB |
Glucuronate transport in via proton symport Dihydroxyvoriconazole Glucuronide, periplasmatic |
Dihydroxyvoriconazole_glc[p] + h[p] -> Dihydroxyvoriconazole_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00582 |
Dihydroxyvoriconazole_Glc |
Dihydroxyvoriconazole_Glc |
n.a. |
Dihydroxyvoriconazole Glucuronide diffusion extracellular to periplasm |
Dihydroxyvoriconazole_glc[e] <=> Dihydroxyvoriconazole_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00582 |
Dihydroxyvoriconazole |
Dihydroxyvoriconazole |
n.a. |
beta-glucuronidase reaction product export Dihydroxyvoriconazole |
Dihydroxyvoriconazole[c] -> Dihydroxyvoriconazole[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00582 |
Dihydroxyvoriconazole |
Dihydroxyvoriconazole |
n.a. |
beta-glucuronidase reaction product export Dihydroxyvoriconazole, periplasmatic |
Dihydroxyvoriconazole[c] -> Dihydroxyvoriconazole[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00582 |
Dihydroxyvoriconazole |
Dihydroxyvoriconazole |
n.a. |
Dihydroxyvoriconazole diffusion extracellular to periplasm |
Dihydroxyvoriconazole[e] <=> Dihydroxyvoriconazole[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
L-Dopamine |
N.A. |
TyrP |
L-Dopa/Dopamine antiport |
L-Dopamine[e] + Dopamine[c] <=> L-Dopamine[c] Dopamine[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
L-Dopamine |
N.A. |
TyrNhaC |
L-Dopa/Dopamine antiport via Na+ and proton |
L-Dopamine[e] + na1[e] + Dopamine[c] + h[c] <=> L-Dopamine[c] + na1[c] + Dopamine[e] + h[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00988 |
Dopamine |
N.A. |
Dadh |
Dopamine dehydroxylase |
Dopamine[c] + h2o[c] + nadp[c] -> h[c] + nadph[c] + o2[c] + mtym[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 31196984 |
| DB00988 |
Dopamine |
Dopamine |
Tdc |
Dopamine transport out via proton symport |
Dopamine[c] + h[c] -> Dopamine[e] + h[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB14682 |
Dextrorphan_Glc |
Dextrorphan |
UidAc |
Dextrorphan O-Glucuronide beta-glucuronidase |
Dextrorphan_glc[c] + h2o[c] -> Dextrorphan[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB14682 |
Dextrorphan_Glc |
Dextrorphan |
UidAe |
Dextrorphan O-Glucuronide beta-glucuronidase extracellular |
Dextrorphan_glc[e] + h2o[e] -> Dextrorphan[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB14682 |
Dextrorphan_Glc |
Dextrorphan |
UidAe |
Dextrorphan O-Glucuronide beta-glucuronidase extracellular, periplasmatic |
Dextrorphan_glc[p] + h2o[p] -> Dextrorphan[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB14682 |
Dextrorphan_Glc |
Dextrorphan_Glc |
UidABC |
Predicted glucuronide ABC transporter Dextrorphan O-Glucuronide |
atp[c] + Dextrorphan_glc[e] + h2o[c] -> adp[c] + Dextrorphan_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB14682 |
Dextrorphan_Glc |
Dextrorphan_Glc |
UidP |
Transport of D-Glucuronate Dextrorphan O-Glucuronide |
Dextrorphan_glc[e] -> Dextrorphan_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB14682 |
Dextrorphan_Glc |
Dextrorphan_Glc |
UidB |
Glucuronate transport in via proton symport Dextrorphan O-Glucuronide |
Dextrorphan_glc[e] + h[e] -> Dextrorphan_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB14682 |
Dextrorphan_Glc |
Dextrorphan_Glc |
UidB |
Glucuronate transport in via proton symport Dextrorphan O-Glucuronide, periplasmatic |
Dextrorphan_glc[p] + h[p] -> Dextrorphan_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB14682 |
Dextrorphan_Glc |
Dextrorphan_Glc |
n.a. |
Dextrorphan O-Glucuronide diffusion extracellular to periplasm |
Dextrorphan_glc[e] <=> Dextrorphan_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB14682 |
Dextrorphan |
Dextrorphan |
n.a. |
beta-glucuronidase reaction product export Dextrorphan |
Dextrorphan[c] -> Dextrorphan[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB14682 |
Dextrorphan |
Dextrorphan |
n.a. |
beta-glucuronidase reaction product export Dextrorphan, periplasmatic |
Dextrorphan[c] -> Dextrorphan[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB14682 |
Dextrorphan |
Dextrorphan |
n.a. |
Dextrorphan diffusion extracellular to periplasm |
Dextrorphan[e] <=> Dextrorphan[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
Efavirenz_Glc |
Efavirenz |
UidAc |
Efavirenz Glucuronide beta-glucuronidase |
Efavirenz_glc[c] + h2o[c] -> Efavirenz[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 26553012 |
| DB00625 |
Efavirenz_Glc |
Efavirenz |
UidAe |
Efavirenz Glucuronide beta-glucuronidase extracellular |
Efavirenz_glc[e] + h2o[e] -> Efavirenz[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 26553012 |
| DB00625 |
Efavirenz_Glc |
Efavirenz |
UidAe |
Efavirenz Glucuronide beta-glucuronidase extracellular, periplasmatic |
Efavirenz_glc[p] + h2o[p] -> Efavirenz[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00625 |
Efavirenz_Glc |
Efavirenz_Glc |
UidABC |
Predicted glucuronide ABC transporter Efavirenz Glucuronide |
atp[c] + Efavirenz_glc[e] + h2o[c] -> adp[c] + Efavirenz_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
Efavirenz_Glc |
Efavirenz_Glc |
UidP |
Transport of D-Glucuronate Efavirenz Glucuronide |
Efavirenz_glc[e] -> Efavirenz_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
Efavirenz_Glc |
Efavirenz_Glc |
UidB |
Glucuronate transport in via proton symport Efavirenz Glucuronide |
Efavirenz_glc[e] + h[e] -> Efavirenz_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
Efavirenz_Glc |
Efavirenz_Glc |
UidB |
Glucuronate transport in via proton symport Efavirenz Glucuronide, periplasmatic |
Efavirenz_glc[p] + h[p] -> Efavirenz_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
Efavirenz_Glc |
Efavirenz_Glc |
n.a. |
Efavirenz Glucuronide diffusion extracellular to periplasm |
Efavirenz_glc[e] <=> Efavirenz_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
Efavirenz |
Efavirenz |
n.a. |
beta-glucuronidase reaction product export Efavirenz |
Efavirenz[c] -> Efavirenz[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
Efavirenz |
Efavirenz |
n.a. |
beta-glucuronidase reaction product export Efavirenz, periplasmatic |
Efavirenz[c] -> Efavirenz[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
Efavirenz |
Efavirenz |
n.a. |
Efavirenz diffusion extracellular to periplasm |
Efavirenz[e] <=> Efavirenz[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB06210 |
Eltrombopag_Glc |
Eltrombopag |
UidAc |
Eltrombopag Glucuronide (M2) beta-glucuronidase |
Eltrombopag_glc[c] + h2o[c] -> Eltrombopag[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB06210 |
Eltrombopag_Glc |
Eltrombopag |
UidAe |
Eltrombopag Glucuronide (M2) beta-glucuronidase extracellular |
Eltrombopag_glc[e] + h2o[e] -> Eltrombopag[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB06210 |
Eltrombopag_Glc |
Eltrombopag |
UidAe |
Eltrombopag Glucuronide (M2) beta-glucuronidase extracellular, periplasmatic |
Eltrombopag_glc[p] + h2o[p] -> Eltrombopag[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB06210 |
Eltrombopag_Glc |
Eltrombopag_Glc |
UidABC |
Predicted glucuronide ABC transporter Eltrombopag Glucuronide (M2) |
atp[c] + Eltrombopag_glc[e] + h2o[c] -> adp[c] + Eltrombopag_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB06210 |
Eltrombopag_Glc |
Eltrombopag_Glc |
UidP |
Transport of D-Glucuronate Eltrombopag Glucuronide (M2) |
Eltrombopag_glc[e] -> Eltrombopag_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB06210 |
Eltrombopag_Glc |
Eltrombopag_Glc |
UidB |
Glucuronate transport in via proton symport Eltrombopag Glucuronide (M2) |
Eltrombopag_glc[e] + h[e] -> Eltrombopag_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB06210 |
Eltrombopag_Glc |
Eltrombopag_Glc |
UidB |
Glucuronate transport in via proton symport Eltrombopag Glucuronide (M2), periplasmatic |
Eltrombopag_glc[p] + h[p] -> Eltrombopag_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB06210 |
Eltrombopag_Glc |
Eltrombopag_Glc |
n.a. |
Eltrombopag Glucuronide (M2) diffusion extracellular to periplasm |
Eltrombopag_glc[e] <=> Eltrombopag_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB06210 |
Eltrombopag_M3 |
Sb-611855 (Intermediate Of M3) |
UidAc |
Eltrombopag M3 (Glucuronide Conjugate) beta-glucuronidase |
Eltrombopag_m3[c] + 2 ahcys[c] + 2 nadh[c] + 4 h[c] -> Sb-611855 (Intermediate Of M3)[c] + glcur[c] + 2 amet[c] + 2 nad[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
N.A. |
Sb-611855 (Intermediate Of M3) |
UidAe |
Eltrombopag M3 (Glucuronide Conjugate) beta-glucuronidase extracellular |
Eltrombopag_m3[e] 2 ahcys[c] + 2 nadh[c] + 4 h[c] -> Sb-611855 (Intermediate Of M3)[e] + glcur[e] + 2 amet[c] + 2 nad[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB06210 |
Eltrombopag_M3 |
Sb-611855 (Intermediate Of M3) |
UidAe |
Eltrombopag M3 (Glucuronide Conjugate) beta-glucuronidase extracellular, periplasmatic |
2 ahcys[c] + 4 h[c] + 2 nadh[c] + Eltrombopag_m3[p] -> 2 amet[c] + 2 nad[c] + glcur[p] + Sb-611855 (Intermediate Of M3)[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB06210 |
Eltrombopag_M3 |
Eltrombopag_M3 |
UidABC |
Predicted glucuronide ABC transporter Eltrombopag M3 (Glucuronide Conjugate) |
atp[c] + Eltrombopag_m3[e] + h2o[c] -> adp[c] + Eltrombopag_m3[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB06210 |
Eltrombopag_M3 |
Eltrombopag_M3 |
UidP |
Transport of D-Glucuronate Eltrombopag M3 (Glucuronide Conjugate) |
Eltrombopag_m3[e] -> Eltrombopag_m3[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB06210 |
Eltrombopag_M3 |
Eltrombopag_M3 |
UidB |
Glucuronate transport in via proton symport Eltrombopag M3 (Glucuronide Conjugate) |
Eltrombopag_m3[e] + h[e] -> Eltrombopag_m3[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB06210 |
Eltrombopag_M3 |
Eltrombopag_M3 |
UidB |
Glucuronate transport in via proton symport Eltrombopag M3 (Glucuronide Conjugate), periplasmatic |
Eltrombopag_m3[p] + h[p] -> Eltrombopag_m3[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB06210 |
Eltrombopag_M3 |
Eltrombopag_M3 |
n.a. |
Eltrombopag M3 (Glucuronide Conjugate) diffusion extracellular to periplasm |
Eltrombopag_m3[e] <=> Eltrombopag_m3[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB06210 |
Eltrombopag_M4 |
Sb_Y (Intermediate Of M4) |
UidAc |
Eltrombopag M4 (Glucuronide Conjugate) beta-glucuronidase |
Eltrombopag_m4[c] + h2o[c] -> Sb_Y (Intermediate Of M4)[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB06210 |
Eltrombopag_M4 |
Sb_Y (Intermediate Of M4) |
UidAe |
Eltrombopag M4 (Glucuronide Conjugate) beta-glucuronidase extracellular |
Eltrombopag_m4[e] + h2o[e] -> Sb_Y (Intermediate Of M4)[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB06210 |
Eltrombopag_M4 |
Sb_Y (Intermediate Of M4) |
UidAe |
Eltrombopag M4 (Glucuronide Conjugate) beta-glucuronidase extracellular, periplasmatic |
Eltrombopag_m4[p] + h2o[p] -> glcur[p] + h[p] + Sb_Y (Intermediate Of M4)[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB06210 |
Eltrombopag_M4 |
Eltrombopag_M4 |
UidABC |
Predicted glucuronide ABC transporter Eltrombopag M4 (Glucuronide Conjugate) |
atp[c] + Eltrombopag_m4[e] + h2o[c] -> adp[c] + Eltrombopag_m4[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB06210 |
Eltrombopag_M4 |
Eltrombopag_M4 |
UidP |
Transport of D-Glucuronate Eltrombopag M4 (Glucuronide Conjugate) |
Eltrombopag_m4[e] -> Eltrombopag_m4[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB06210 |
Eltrombopag_M4 |
Eltrombopag_M4 |
UidB |
Glucuronate transport in via proton symport Eltrombopag M4 (Glucuronide Conjugate) |
Eltrombopag_m4[e] + h[e] -> Eltrombopag_m4[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB06210 |
Eltrombopag_M4 |
Eltrombopag_M4 |
UidB |
Glucuronate transport in via proton symport Eltrombopag M4 (Glucuronide Conjugate), periplasmatic |
Eltrombopag_m4[p] + h[p] -> Eltrombopag_m4[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB06210 |
Eltrombopag_M4 |
Eltrombopag_M4 |
n.a. |
Eltrombopag M4 (Glucuronide Conjugate) diffusion extracellular to periplasm |
Eltrombopag_m4[e] <=> Eltrombopag_m4[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB06210 |
Eltrombopag |
Eltrombopag |
n.a. |
beta-glucuronidase reaction product export Eltrombopag |
Eltrombopag[c] -> Eltrombopag[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB06210 |
Eltrombopag |
Eltrombopag |
n.a. |
beta-glucuronidase reaction product export Eltrombopag, periplasmatic |
Eltrombopag[c] -> Eltrombopag[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB06210 |
Eltrombopag |
Eltrombopag |
n.a. |
Eltrombopag diffusion extracellular to periplasm |
Eltrombopag[e] <=> Eltrombopag[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00783 |
Estradiolglc |
Estradiolglc |
UidABC |
Predicted glucuronide ABC transporter estradiol-17-glucuronide |
atp[c] + Estradiolglc[e] + h2o[c] -> adp[c] + Estradiolglc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00783 |
Estradiolglc |
Estradiol |
UidAc |
Estradiol-17-glucuronide beta-glucuronidase |
Estradiolglc[c] + h2o[c] -> Estradiol[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 31636122 |
| DB00783 |
Estradiolglc |
Estradiol |
UidAe |
Estradiol-17-glucuronide beta-glucuronidase extracellular |
Estradiolglc[e] + h2o[e] -> Estradiol[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 31636122 |
| DB00783 |
Estradiolglc |
Estradiol |
UidAe |
Estradiol-17-glucuronide beta-glucuronidase extracellular, periplasmatic |
Estradiolglc[p] + h2o[p] -> Estradiol[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00783 |
Estradiolglc |
Estradiolglc |
UidB |
Glucuronate transport in via proton symport estradiol-17-glucuronide |
Estradiolglc[e] + h[e] -> Estradiolglc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00783 |
Estradiolglc |
Estradiolglc |
UidB |
Glucuronate transport in via proton symport estradiol-17-glucuronide, periplasmatic |
Estradiolglc[p] + h[p] -> Estradiolglc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00783 |
Estradiolglc |
Estradiolglc |
n.a. |
17beta-estradiol 3-glucosiduronic acid diffusion extracellular to periplasm |
Estradiolglc[e] <=> Estradiolglc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00783 |
Estradiol |
Estradiol |
n.a. |
beta-glucuronidase reaction product export estradiol |
Estradiol[c] <=> Estradiol[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00783 |
Estradiol |
Estradiol |
n.a. |
beta-glucuronidase reaction product export estradiol, periplasmatic |
Estradiol[c] -> Estradiol[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00783 |
Estradiol |
Estradiol |
n.a. |
estradiol diffusion extracellular to periplasm |
Estradiol[e] <=> Estradiol[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00783 |
Estradiolglc |
Estradiolglc |
UidP |
Transport of estradiol-17-glucuronide |
Estradiolglc[e] -> Estradiolglc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB04573 |
Estriolglc |
Estriol |
UidAc |
Estriol-16-glucuronide beta-glucuronidase |
Estriolglc[c] + h2o[c] -> Estriol[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 31636122 |
| DB04573 |
Estriolglc |
Estriol |
UidAe |
Estriol-16-glucuronide beta-glucuronidase extracellular |
Estriolglc[e] + h2o[e] -> Estriol[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 31636122 |
| DB04573 |
Estriolglc |
Estriol |
UidAe |
Estriol-16-glucuronide beta-glucuronidase extracellular, periplasmatic |
Estriolglc[p] + h2o[p] -> Estriol[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB04573 |
Estriolglc |
Estriolglc |
UidABC |
Predicted glucuronide ABC transporter estriol-16-glucuronide |
atp[c] + Estriolglc[e] + h2o[c] -> adp[c] + Estriolglc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB04573 |
Estriolglc |
Estriolglc |
UidB |
Glucuronate transport in via proton symport estriol-16-glucuronide |
Estriolglc[e] + h[e] -> Estriolglc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB04573 |
Estriolglc |
Estriolglc |
UidB |
Glucuronate transport in via proton symport estriol-16-glucuronide, periplasmatic |
Estriolglc[p] + h[p] -> Estriolglc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB04573 |
Estriolglc |
Estriolglc |
n.a. |
16-Glucuronide-estriol diffusion extracellular to periplasm |
Estriolglc[e] <=> Estriolglc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB04573 |
Estriol |
Estriol |
n.a. |
beta-glucuronidase reaction product export estradiol |
Estriol[c] -> Estriol[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB04573 |
Estriol |
Estriol |
n.a. |
beta-glucuronidase reaction product export estriol, periplasmatic |
Estriol[c] -> Estriol[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB04573 |
Estriol |
Estriol |
n.a. |
estriol diffusion extracellular to periplasm |
Estriol[e] <=> Estriol[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB04573 |
Estriolglc |
Estriolglc |
UidP |
Transport of estriol-16-glucuronide |
Estriolglc[e] -> Estriolglc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00655 |
Estroneglc |
Estrone |
UidAc |
Estrone-3-glucuronide beta-glucuronidase |
Estroneglc[c] + h2o[c] -> Estrone[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 31636122 |
| DB00655 |
Estroneglc |
Estrone |
UidAe |
Estrone-3-glucuronide beta-glucuronidase extracellular |
Estroneglc[e] + h2o[e] -> Estrone[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 31636122 |
| DB00655 |
Estroneglc |
Estrone |
UidAe |
Estrone-3-glucuronide beta-glucuronidase extracellular, periplasmatic |
Estroneglc[p] + h2o[p] -> Estrone[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00655 |
Estroneglc |
Estroneglc |
UidABC |
Predicted glucuronide ABC transporter Estrone-3-glucuronide |
atp[c] + Estroneglc[e] + h2o[c] -> adp[c] + Estroneglc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00655 |
Estroneglc |
Estroneglc |
UidB |
Glucuronate transport in via proton symport Estrone-3-glucuronide |
Estroneglc[e] + h[e] -> Estroneglc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00655 |
Estroneglc |
Estroneglc |
UidB |
Glucuronate transport in via proton symport Estrone-3-glucuronide, periplasmatic |
Estroneglc[p] + h[p] -> Estroneglc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00655 |
Estroneglc |
Estroneglc |
n.a. |
estrone 3-glucosiduronic acid diffusion extracellular to periplasm |
Estroneglc[e] <=> Estroneglc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00655 |
Estrone |
Estrone |
n.a. |
beta-glucuronidase reaction product export Estrone |
Estrone[c] -> Estrone[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00655 |
Estrone |
Estrone |
n.a. |
estrone diffusion extracellular to periplasm |
Estrone[e] <=> Estrone[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00655 |
Estrone |
Estrone |
n.a. |
beta-glucuronidase reaction product export estrone, periplasmatic |
Estrone[c] -> Estrone[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00655 |
Estroneglc |
Estroneglc |
UidP |
Transport of Estrone-3-glucuronide |
Estroneglc[e] -> Estroneglc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
1-Hydroxy S-Ibuprofen |
N.A. |
n.a. |
1-hydroxy S-ibuprofen exchange |
1-hydroxy S-ibuprofen[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
1-Hydroxy S-Ibuprofen-Glucuronide |
N.A. |
n.a. |
1-hydroxy S-ibuprofen-glucuronide exchange |
1-hydroxy S-ibuprofen-glucuronide[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
1'-Oh-Midazolam-Glucuronide |
N.A. |
n.a. |
1-OH-midazolam-glucuronide exchange |
1'-OH-midazolam-glucuronide[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
1'-Oh-Midazolam |
N.A. |
n.a. |
1-OH-midazolam exchange |
1'-OH-midazolam[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Acid |
N.A. |
n.a. |
2-hydroxy-atorvastatin-acid / ortho-hydroxy-atorvastatin acid exchange |
2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin acid[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Acidgluc |
N.A. |
n.a. |
2-hydroxy-atorvastatin-acyl-glucuronide exchange |
2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin acidgluc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Lactone |
N.A. |
n.a. |
2-hydroxy-atorvastatin-lactone / ortho-hydroxy-atorvastatin lactone exchange |
2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin lactone[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
2-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone / Ortho-Hydroxy-Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Lactonegluc |
N.A. |
n.a. |
2-hydroxy-atorvastatin-lactone-glucuronide exchange |
2-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone / ortho-hydroxy-atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin lactonegluc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
2-Hydroxy-S-Ibuprofen |
N.A. |
n.a. |
2-hydroxy-S-ibuprofen exchange |
2-hydroxy-S-ibuprofen[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
2-Hydroxy S-Ibuprofen-Glucuronide |
N.A. |
n.a. |
2-hydroxy S-ibuprofen-glucuronide exchange |
2-hydroxy S-ibuprofen-glucuronide[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00564 |
2-Hydroxycarbamazepine |
N.A. |
n.a. |
2-Hydroxycarbamazepine exchange |
2-Hydroxycarbamazepine[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00564 |
2-Hydroxycarbamazepine_Glc |
N.A. |
n.a. |
2-Hydroxy Carbamazepine Glucuronide exchange |
2-Hydroxycarbamazepine_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00916 |
2-Hydroxymetronidazole |
N.A. |
n.a. |
2-Hydroxymetronidazole exchange |
2-Hydroxymetronidazole[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00916 |
2-Hydroxymetronidazole_Glc |
N.A. |
n.a. |
2-Hydroxymetronidazole Glucuronide exchange |
2-Hydroxymetronidazole_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01235 |
L-Dopamine |
N.A. |
n.a. |
Exchange of 3, 4-Dihydroxy-L-Phenylalanine |
L-Dopamine[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
3-Hydroxy S-Ibuprofen |
N.A. |
n.a. |
3-hydroxy S-ibuprofen exchange |
3-hydroxy S-ibuprofen[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
3-Hydroxy S-Ibuprofen-Glucuronide |
N.A. |
n.a. |
3-hydroxy S-ibuprofen-glucuronide exchange |
3-hydroxy S-ibuprofen-glucuronide[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
3-Methoxy-Acetaminophen |
N.A. |
n.a. |
3-methoxy-acetaminophen exchange |
3-methoxy-acetaminophen[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00564 |
3-Hydroxycarbamazepine |
N.A. |
n.a. |
3-Hydroxycarbamazepine exchange |
3-Hydroxycarbamazepine[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00564 |
3-Hydroxycarbamazepine_Glc |
N.A. |
n.a. |
3-Hydroxy Carbamazepine Glucuronide exchange |
3-Hydroxycarbamazepine_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00967 |
3-Hydroxydesloratadine |
N.A. |
n.a. |
3-Hydroxydesloratadine exchange |
3-Hydroxydesloratadine[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00967 |
3-Hydroxydesloratadine_Glc |
N.A. |
n.a. |
3-Hydroxydesloratadine Glucuronide exchange |
3-Hydroxydesloratadine_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
3-Hydroxy N-Desethylamiodaronedarone (3-Hydroxy_Mdea) (M8) |
N.A. |
n.a. |
3-Hydroxy N-Desethylamiodarone (3-Hydroxy_MDEA) (M8) exchange |
3-Hydroxy N-DesethylAmiodaronedarone (3-Hydroxy_MDEA) (M8)[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
3-Hydroxy N-Desethylamiodaronedarone (3-Hydroxy_Mdea) (M8)_Glc |
N.A. |
n.a. |
3-Hydroxy N-Desethylamiodarone Glucuronide (3-Hydroxy_MDEA_Glc) (M15) exchange |
3-Hydroxy N-DesethylAmiodaronedarone (3-Hydroxy_MDEA) (M8)_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
3-Hydroxymorphinan |
N.A. |
n.a. |
3-Hydroxymorphinan exchange |
3-Hydroxymorphinan[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
3-Hydroxymorphinan_Glc |
N.A. |
n.a. |
3-Hydroxymorphinan O-Glucuronide exchange |
3-Hydroxymorphinan_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB12449 |
4-Dehydroxytempol |
N.A. |
n.a. |
4-Dehydroxytempol exchange |
4-Dehydroxytempol[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB12449 |
4-Dehydroxytempol_1Glc |
N.A. |
n.a. |
4-Dehydroxytempol 1-O-Glucuronide exchange |
4-Dehydroxytempol_1glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
4-Oh-Midazolam-Glucuronide |
N.A. |
n.a. |
4-OH-midazolam-glucuronide exchange |
4-OH-midazolam-glucuronide[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
4-Hydroxyphenylacetate |
N.A. |
n.a. |
Exchange of 4-Hydroxyphenylacetate |
4hphac[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00586 |
4-Hydroxydiclofenac |
N.A. |
n.a. |
4-Hydroxydiclofenac exchange |
4-Hydroxydiclofenac[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00586 |
4-Hydroxydiclofenac_Glc |
N.A. |
n.a. |
4-Hydroxydiclofenac Glucuronide exchange |
4-Hydroxydiclofenac_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01009 |
4-Hydroxybenzyl Ketoprofen |
N.A. |
n.a. |
4-Hydroxybenzyl Ketoprofen exchange |
4-Hydroxybenzyl Ketoprofen[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01009 |
4-Hydroxybenzyl Ketoprofen_Glc |
N.A. |
n.a. |
4-Hydroxybenzyl Ketoprofen Glucuronide exchange |
4-Hydroxybenzyl Ketoprofen_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB11596 |
4-Hydroxy Levamisonidazolele (M1) |
N.A. |
n.a. |
4-Hydroxy Levamisole (M1) exchange |
4-Hydroxy LevaMisonidazolele (M1)[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB11596 |
4-Hydroxy Levamisonidazolele (M1)_Glc |
N.A. |
n.a. |
4-Hydroxy Levamisole Glucuronide exchange |
4-Hydroxy LevaMisonidazolele (M1)_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01577 |
4-Hydroxymethamphetamine |
N.A. |
n.a. |
4-Hydroxymethamphetamine exchange |
4-Hydroxymethamphetamine[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01577 |
4-Hydroxymethamphetamine_Glc |
N.A. |
n.a. |
4-Hydroxymethamphetamine Glucuronide exchange |
4-Hydroxymethamphetamine_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00571 |
4-Hydroxypropanolol |
N.A. |
n.a. |
4-Hydroxypropanolol exchange |
4-Hydroxypropanolol[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00571 |
4-Hydroxypropanolol_Glc |
N.A. |
n.a. |
4-Hydroxypropranolol Glucuronide exchange |
4-Hydroxypropanolol_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00897 |
4-Hydroxytriazolam |
N.A. |
n.a. |
4-Hydroxytriazolam exchange |
4-Hydroxytriazolam[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00897 |
4-Hydroxytriazolam_Glc |
N.A. |
n.a. |
4-Hydroxy Triazolam Glucuronide exchange |
4-Hydroxytriazolam_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00582 |
4-Hydroxyvoriconazole |
N.A. |
n.a. |
4-Hydroxyvoriconazole exchange |
4-Hydroxyvoriconazole[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00582 |
4-Hydroxyvoriconazole_Glc |
N.A. |
n.a. |
4-Hydroxyvoriconazole Glucuronide exchange |
4-Hydroxyvoriconazole_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
4-Oh-Midazolam |
N.A. |
n.a. |
4-OH-midazolam exchange |
4-OH-midazolam[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00233 |
5-Aminosalicylic Acid (Mesalamine) |
N.A. |
n.a. |
5-Aminosalicylic Acid (Mesalamine) exchange |
5-Aminosalicylic Acid (Mesalamine)[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB03419 |
5-Fluorouracil |
N.A. |
n.a. |
5-Fluorouracil exchange |
5-Fluorouracil[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00891 |
5-Hydroxy-Sulfapyridine |
N.A. |
n.a. |
5-Hydroxy-Sulfapyridine exchange |
5-Hydroxy-Sulfapyridine[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00891 |
5-Hydroxy-Sulfapyridine_Glc |
N.A. |
n.a. |
5-Hydroxy-Sulfapyridine-O-Glucuronide exchange |
5-Hydroxy-Sulfapyridine_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
5-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
N.A. |
n.a. |
5-hydroxy-fluvastatin exchange |
5-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
5-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu |
N.A. |
n.a. |
5-hydroxy-fluvastatin-glucuronide exchange |
5-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01120 |
6-Beta-Oh-Gliclazide |
N.A. |
n.a. |
6-beta-OH-gliclazide exchange |
6-beta-OH-gliclazide[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01120 |
6-Beta-Oh-Gliclazideglc |
N.A. |
n.a. |
6-beta-OH-gliclazide-glucuronide exchange |
6-beta-OH-gliclazideglc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
6-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
N.A. |
n.a. |
6-hydroxy-fluvastatin exchange |
6-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
6-Hydroxy-Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu |
N.A. |
n.a. |
6-hydroxy-fluvastatin-glucuronide exchange |
6-hydroxy-fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinglu[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01068 |
7-Aminoclonazepam |
N.A. |
n.a. |
7-Aminoclonazepam exchange |
7-Aminoclonazepam[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01120 |
7-Beta-Oh-Gliclazide |
N.A. |
n.a. |
7-beta-OH-gliclazide exchange |
7-beta-OH-gliclazide[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01120 |
7-Beta-Oh-Gliclazideglc |
N.A. |
n.a. |
7-beta-OH-gliclazide-glucuronide exchange |
7-beta-OH-gliclazideglc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
7-Hydroxy-Efavirenz |
N.A. |
n.a. |
7-hydroxy-Efavirenz exchange |
7-hydroxy-Efavirenz[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
7-Hydroxy-Efavirenz_Glc |
N.A. |
n.a. |
7-hydroxy-Efavirenz Glucuronide exchange |
7-hydroxy-Efavirenz_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
8,14-Dihydroxyefavirenz |
N.A. |
n.a. |
8 14-Dihydroxyefavirenz exchange |
8,14-Dihydroxyefavirenz[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
8,14-Dihydroxyefavirenz_Glc |
N.A. |
n.a. |
8 14-Dihydroxyefavirenz Glucuronide exchange |
8,14-Dihydroxyefavirenz_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
8-Hydroxy-Efavirenz |
N.A. |
n.a. |
8-hydroxy-Efavirenz exchange |
8-hydroxy-Efavirenz[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
8-Hydroxy-Efavirenz_Glc |
N.A. |
n.a. |
8-hydroxy-Efavirenz Glucuronide exchange |
8-hydroxy-Efavirenz_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00160 |
4-Aminobenzoyl-Beta-Alanine |
N.A. |
n.a. |
4-Aminobenzoyl-Beta-Alanine exchange |
4-Aminobenzoyl-Beta-Alanine[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00145 |
Acetyl 4-Aminobenzoylglycinecine |
N.A. |
n.a. |
Acetyl 4-Aminobenzoylglycine exchange |
Acetyl 4-AminobenzoylGlycinecine[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00145 |
Acetyl 4-Aminobenzoylglycinecine_Glc |
N.A. |
n.a. |
Acetyl 4-Aminobenzoylglycine Glucuronide exchange |
Acetyl 4-AminobenzoylGlycinecine_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00233 |
Ac5-Aminosalicylic Acid (Mesalamine) |
N.A. |
n.a. |
N-Acetyl-5-Aminosalicylic Acid exchange |
ac5-Aminosalicylic Acid (Mesalamine)[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00951 |
N-Acetylisoniazid |
N.A. |
n.a. |
N-Acetylisoniazid exchange |
N-Acetylisoniazid[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Acetaminophen |
N.A. |
n.a. |
acetaminophen/paracetamol exchange |
Acetaminophen[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Acetaminophen_Glc |
N.A. |
n.a. |
Acetaminophen Glucuronide exchange |
Acetaminophen_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Acetaminophenglu |
N.A. |
n.a. |
Acetaminophen glucuronide exchange |
Acetaminophenglu[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00404 |
4-Hydroxyalprazolam |
N.A. |
n.a. |
4-Hydroxyalprazolam exchange |
4-Hydroxyalprazolam[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00404 |
4-Hydroxyalprazolam_Glc |
N.A. |
n.a. |
4-Hydroxyalprazolam Glucuronide exchange |
4-Hydroxyalprazolam_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00404 |
Alpha-Hydroxyalprazolam |
N.A. |
n.a. |
Alpha-Hydroxyalprazolam exchange |
Alpha-Hydroxyalprazolam[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00404 |
Alpha-Hydroxyalprazolam_Glc |
N.A. |
n.a. |
Alpha-Hydroxyalprazolam Glucuronide exchange |
Alpha-Hydroxyalprazolam_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Desmethylalfentanil (Am14) |
N.A. |
n.a. |
Desmethylalfentanil (AM14) exchange |
Desmethylalfentanil (AM14)[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Desmethylalfentanil (Am14)_Glc |
N.A. |
n.a. |
Desmethylalfentanil Glucuronide (AM14 Glucuronide) exchange |
Desmethylalfentanil (AM14)_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00091 |
Am1C (Cyclosporine) (M18) |
N.A. |
n.a. |
AM1c (cyclosporine) exchange |
AM1C (Cyclosporine) (M18)[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00091 |
Am1C-Glucuronide (Cyclosporine) |
N.A. |
n.a. |
AM1c-glucuronide (cyclosporine) exchange |
AM1C-Glucuronide (Cyclosporine)[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
N-(4-Hydroxyphenyl)Propanamide (Am5) |
N.A. |
n.a. |
N-(4-Hydroxyphenyl)Propanamide (AM5) exchange |
N-(4-Hydroxyphenyl)Propanamide (AM5)[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
N-(4-Hydroxyphenyl)Propanamide (Am5)_Glc |
N.A. |
n.a. |
N-(4-Hydroxyphenyl)Propanamide Glucuronide (AM5 Glucuronide) exchange |
N-(4-Hydroxyphenyl)Propanamide (AM5)_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Desmethylnoralfentanil (Am6) |
N.A. |
n.a. |
Desmethylnoralfentanil (AM6) exchange |
Desmethylnoralfentanil (AM6)[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Desmethylnoralfentanil (Am6)_Glc |
N.A. |
n.a. |
Desmethylnoralfentanil Glucuronide (AM6 Glucuronide) exchange |
Desmethylnoralfentanil (AM6)_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
Amiodarone |
N.A. |
n.a. |
Amiodarone exchange |
Amiodarone[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Amiodarone_C |
N.A. |
n.a. |
Carboxylamiodarone (M12) exchange |
Amiodarone_c[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Amiodarone_C_Glc |
N.A. |
n.a. |
Carboxylamiodarone Glucuronide (M19) exchange |
Amiodarone_c_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
Amiodarone_Glc |
N.A. |
n.a. |
Amiodarone Glucuronide (M16) exchange |
Amiodarone_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00145 |
4-Aminobenzoylglycinecine |
N.A. |
n.a. |
4-Aminobenzoylglycine exchange |
4-AminobenzoylGlycinecine[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00145 |
4-Aminobenzoylglycinecine_Glc |
N.A. |
n.a. |
4-Aminobenzoylglycine Glucuronide exchange |
4-AminobenzoylGlycinecine_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00915 |
Oxidation Product Of M3 M6 |
N.A. |
n.a. |
Oxidation Product Of M3 M6 exchange |
Oxidation Product Of M3 M6[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00915 |
Oxidation Product Of M3 M6_Glc |
N.A. |
n.a. |
Amantadine M6 Glucuronide exchange |
Oxidation Product Of M3 M6_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
7-Amino Nitrozepam |
N.A. |
n.a. |
7-Amino Nitrozepam exchange |
7-Amino Nitrozepam[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acid |
N.A. |
n.a. |
atorvastatin-acid exchange |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acid[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acyl-Glucuronide / G2 |
N.A. |
n.a. |
atorvastatin-acyl-glucuronide / G2 exchange |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acyl-glucuronide / G2[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Ether-Glucuronide -G1 |
N.A. |
n.a. |
atorvastatin-ether-glucuronide -G1 exchange |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-ether-glucuronide -G1[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactone |
N.A. |
n.a. |
atorvastatin-lactone exchange |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactone[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01076 |
Atorvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Lactonegluc |
N.A. |
n.a. |
atorvastatin-lactone-ether-glucuronide / G3 exchange |
atorvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-lactonegluc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB15994 |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane |
N.A. |
n.a. |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane exchange |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB15994 |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane_Glc |
N.A. |
n.a. |
Bis-(P-Hydroxy-Phenyl)-Pyridyl-2-Methane Glucuronide exchange |
(Bis-(P-Hydroxyphenyl)-Pyridyl-2-Methane_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr 355 |
N.A. |
n.a. |
BILR 355 exchange |
BILR 355[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M10 |
N.A. |
n.a. |
BILR M10 exchange |
BILR M10[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M12 |
N.A. |
n.a. |
BILR M12 exchange |
BILR M12[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M14 |
N.A. |
n.a. |
BILR M14 exchange |
BILR M14[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M15 |
N.A. |
n.a. |
BILR M15 exchange |
BILR M15[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M16 |
N.A. |
n.a. |
BILR M16 exchange |
BILR M16[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Bilr M7 |
N.A. |
n.a. |
BILR M7 exchange |
BILR M7[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB03312 |
Brivudine |
N.A. |
n.a. |
Brivudine exchange |
Brivudine[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00559 |
Bosentan |
N.A. |
n.a. |
Bosentan exchange |
Bosentan[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00559 |
Bosentan_Glc |
N.A. |
n.a. |
Bosentan Glucuronide exchange |
Bosentan_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB03419 |
(E)-5-(2-Bromovinyl)Uracil |
N.A. |
n.a. |
(E)-5-(2-Bromovinyl)Uracil exchange |
(E)-5-(2-Bromovinyl)Uracil[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Benzoate |
N.A. |
n.a. |
Benzoate exchange |
Benzoate[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Benzoate_Glc |
N.A. |
n.a. |
Benzoic acid glucuronide exchange |
Benzoate_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01014 |
Benzoated |
N.A. |
n.a. |
Balsalazide exchange |
Benzoated[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB06777 |
Chenodeoxycholate |
N.A. |
n.a. |
chenodeoxycholate exchange |
chenodeoxyCholate[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
S-Carboxy Ibuprofen |
N.A. |
n.a. |
S-carboxy ibuprofen exchange |
S-carboxy ibuprofen[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
S-Carboxy Ibuprofen Glucuronide |
N.A. |
n.a. |
S-carboxy ibuprofen glucuronide exchange |
S-carboxy ibuprofen glucuronide[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00564 |
Cbenzoate |
N.A. |
n.a. |
Carbamazepine exchange |
cBenzoate[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00564 |
Cbenzoate_Glc |
N.A. |
n.a. |
Carbamazepine Glucuronide exchange |
cBenzoate_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Cd6168 |
N.A. |
n.a. |
CD6168 exchange |
CD6168[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Cd6168_Glc |
N.A. |
n.a. |
CD6168 Glucuronide exchange |
CD6168_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00446 |
Chloramphenicol |
N.A. |
n.a. |
Chloramphenicol exchange |
Chloramphenicol[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00446 |
Chloramphenicol_Glc |
N.A. |
n.a. |
Chloramphenicol 3-Glucuronide exchange |
Chloramphenicol_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Cholate |
N.A. |
n.a. |
exchange reaction for cholate |
Cholate[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00482 |
Celecoxib |
N.A. |
n.a. |
Celecoxib exchange |
Celecoxib[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00482 |
Celecoxib_C |
N.A. |
n.a. |
Carboxycelecoxib exchange |
Celecoxib_c[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00482 |
Celecoxib_C_Glc |
N.A. |
n.a. |
Carboxycelecoxib Glucuronide exchange |
Celecoxib_c_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00482 |
Celecoxib_Glc |
N.A. |
n.a. |
Celecoxib Glucuronide exchange |
Celecoxib_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00758 |
Clopidogrel Carboxylic Acid |
N.A. |
n.a. |
Clopidogrel Carboxylic Acid exchange |
Clopidogrel Carboxylic Acid[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00758 |
Clopidogrel Acyl-Beta-D-Glucuronide |
N.A. |
n.a. |
Clopidogrel Acyl-Beta-D-Glucuronide exchange |
Clopidogrel Acyl-Beta-D-Glucuronide[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00439 |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1 |
N.A. |
n.a. |
cerivastatin-M1 exchange |
cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00439 |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23 |
N.A. |
n.a. |
cerivastatin-M23 exchange |
cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00439 |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1-Glucuronide |
N.A. |
n.a. |
cerivastatin-M1-glucuronide exchange |
cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M1-glucuronide[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00439 |
Cerivasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23-Glucuronide |
N.A. |
n.a. |
cerivastatin-M23-glucuronide exchange |
cerivasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-M23-glucuronide[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01068 |
Clonazepam |
N.A. |
n.a. |
Clonazepam exchange |
Clonazepam[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
Deaminated Amiodarone (M5) |
N.A. |
n.a. |
Deaminated Amiodarone (M5) exchange |
Deaminated Amiodarone (M5)[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
Deaminated Amiodarone (M5)_Glc |
N.A. |
n.a. |
Deaminated Amiodarone Glucuronide (M14) exchange |
Deaminated Amiodarone (M5)_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00586 |
Diclofenac |
N.A. |
n.a. |
Diclofenac exchange |
Diclofenac[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00586 |
Diclofenac_Glc |
N.A. |
n.a. |
Diclofenac Acyl Glucuronide exchange |
Diclofenac_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
Di-N-Desethylamiodarone (Ddea) |
N.A. |
n.a. |
Di-N-Desethylamiodarone (DDEA) exchange |
Di-N-Desethylamiodarone (DDEA) [e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01118 |
Di-N-Desethylamiodarone (Ddea) _Glc |
N.A. |
n.a. |
Di-N-Desethylamiodarone Glucuronide Conjugate (DDEA_Glc) exchange |
Di-N-Desethylamiodarone (DDEA) _glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00637 |
Desmethylastemizole |
N.A. |
n.a. |
Desmethylastemizole exchange |
Desmethylastemizole[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00637 |
Desmethylastemizole_Glc |
N.A. |
n.a. |
Desmethylastemozole Glucuronide exchange |
Desmethylastemizole_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00441 |
Gemci1,2,4-Triaminobenzeneine (2',2'-Difluorodeoxycytidine) |
N.A. |
n.a. |
Gemcitabine (2' 2'-difluorodeoxycytidine) exchange |
Gemci1,2,4-Triaminobenzeneine (2',2'-difluorodeoxycytidine)[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB02745 |
2',2'-Difluorodeoxyuridine |
N.A. |
n.a. |
2 2-Difluorodeoxyuridine exchange |
2',2'-Difluorodeoxyuridine[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Glycinecochenodeoxycholate |
N.A. |
n.a. |
Chenodeoxyglycocholate exchange |
Glycinecochenodeoxycholate[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB03419 |
Dh5-Fluorouracil |
N.A. |
n.a. |
5,6-Dihydro 5-Fluoro Uracil exchange |
dh5-Fluorouracil[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01396 |
Digitoxin |
N.A. |
n.a. |
Digitoxin exchange |
Digitoxin[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01396 |
Digoxin |
N.A. |
n.a. |
Digoxin exchange |
Digoxin[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01396 |
Digoxin_Glc |
N.A. |
n.a. |
Digoxin 16-Glucuronide exchange |
Digoxin_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01396 |
Dihydro_Digitoxin |
N.A. |
n.a. |
20,22-Dihydrodigitoxin exchange |
dihydro_Digitoxin[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00390 |
Dihydro_Digoxin |
N.A. |
n.a. |
Dihydrodigoxin exchange |
dihydro_Digoxin[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB14850 |
Deleobuvir |
N.A. |
n.a. |
Deleobuvir exchange |
Deleobuvir[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB14850 |
Deleobuvir_Glc |
N.A. |
n.a. |
Deleobuvir Glucuronide exchange |
Deleobuvir_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
5-O-Desmethyl Donepezil |
N.A. |
n.a. |
5-O-Desmethyl Donepezil exchange |
5-O-Desmethyl Donepezil[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
6-O-Desmethyldonepezil |
N.A. |
n.a. |
6-O-Desmethyldonepezil exchange |
6-O-Desmethyldonepezil[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M11 |
N.A. |
n.a. |
Donepezil Metabolite M11 exchange |
Donepezil Me1,2,4-Triaminobenzeneolite M11[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M12 |
N.A. |
n.a. |
Donepezil Metabolite M12 exchange |
Donepezil Me1,2,4-Triaminobenzeneolite M12[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M13 |
N.A. |
n.a. |
Donepezil Metabolite M13 exchange |
Donepezil Me1,2,4-Triaminobenzeneolite M13[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M14 |
N.A. |
n.a. |
Donepezil Metabolite M14 exchange |
Donepezil Me1,2,4-Triaminobenzeneolite M14[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00843 |
Donepezil Me1,2,4-Triaminobenzeneolite M9 |
N.A. |
n.a. |
Donepezil Metabolite M9 exchange |
Donepezil Me1,2,4-Triaminobenzeneolite M9[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB06414 |
Etravarine Dihydroxylated (M4, M5, M6) |
N.A. |
n.a. |
Etravarine Dihydroxylated (M4 M5 M6) exchange |
Etravarine Dihydroxylated (M4, M5, M6)[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB06414 |
Etravarine Dihydroxylated (M4, M5, M6)_Glc |
N.A. |
n.a. |
Etravarine Dihydroxylated Glucuronide exchange |
Etravarine Dihydroxylated (M4, M5, M6)_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00582 |
Dihydroxyvoriconazole |
N.A. |
n.a. |
Dihydroxyvoriconazole exchange |
Dihydroxyvoriconazole[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00582 |
Dihydroxyvoriconazole_Glc |
N.A. |
n.a. |
Dihydroxyvoriconazole Glucuronide exchange |
Dihydroxyvoriconazole_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00988 |
Dopamine |
N.A. |
n.a. |
Exchange of Dopamine |
Dopamine[e] <= |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB14682 |
Dextrorphan |
N.A. |
n.a. |
Dextrorphan exchange |
Dextrorphan[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB14682 |
Dextrorphan_Glc |
N.A. |
n.a. |
Dextrorphan O-Glucuronide exchange |
Dextrorphan_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
Efavirenz |
N.A. |
n.a. |
Efavirenz exchange |
Efavirenz[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00625 |
Efavirenz_Glc |
N.A. |
n.a. |
Efavirenz Glucuronide exchange |
Efavirenz_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB06210 |
Eltrombopag |
N.A. |
n.a. |
Eltrombopag exchange |
Eltrombopag[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB06210 |
Eltrombopag_Glc |
N.A. |
n.a. |
Eltrombopag Glucuronide (M2) exchange |
Eltrombopag_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB06210 |
Eltrombopag_M3 |
N.A. |
n.a. |
Eltrombopag M3 (Glucuronide Conjugate) exchange |
Eltrombopag_m3[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB06210 |
Eltrombopag_M4 |
N.A. |
n.a. |
Eltrombopag M4 (Glucuronide Conjugate) exchange |
Eltrombopag_m4[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00783 |
Estradiol |
N.A. |
n.a. |
Estradiol exchange |
Estradiol[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00783 |
Estradiolglc |
N.A. |
n.a. |
Estradiol-17-glucuronide exchange |
Estradiolglc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB04573 |
Estriol |
N.A. |
n.a. |
estriol exchange |
Estriol[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB04573 |
Estriolglc |
N.A. |
n.a. |
Estriol-16-glucuronide exchange |
Estriolglc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00655 |
Estrone |
N.A. |
n.a. |
Estrone exchange |
Estrone[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00655 |
Estroneglc |
N.A. |
n.a. |
Estrone-3-glucuronide exchange |
Estroneglc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00973 |
Ezetimibe |
N.A. |
n.a. |
Ezetimibe exchange |
Ezetimibe[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00973 |
Ezetimibe_Glc |
N.A. |
n.a. |
Ezetimibe Glucuronide exchange |
Ezetimibe_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
5-Fluorocytosine |
N.A. |
n.a. |
5-Fluorocytosine exchange |
5-Fluorocytosine[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
N.A. |
n.a. |
fluvastatin exchange |
fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
N.A. |
n.a. |
fluvstatin-glucuronide exchange |
fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintet |
N.A. |
n.a. |
des-isopropyl-dihydro-fluvastatin-tetranor exchange |
fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintet[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintetglu |
N.A. |
n.a. |
des-isopropyl-dihydro-fluvastatin-tetranor-glucuronide exchange |
fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintetglu[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Glycinecocholate |
N.A. |
n.a. |
Glycocholate exchange |
Glycinecocholate[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Glucuronide-Conjugate Of 3-Methoxy-Acetaminophen |
N.A. |
n.a. |
glucuronide-conjugate of 3-methoxy-acetaminophen exchange |
glucuronide-conjugate of 3-methoxy-acetaminophen[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00674 |
Galantamine |
N.A. |
n.a. |
Galantamine exchange |
Galantamine[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00674 |
Galantamine_Glc |
N.A. |
n.a. |
Galantamine Glucuronide exchange |
Galantamine_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00145 |
Glycine |
N.A. |
n.a. |
exchange reaction for Glycine |
Glycine[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil |
N.A. |
n.a. |
Gemfibrozil exchange |
Gemfibrozil[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Glc |
N.A. |
n.a. |
Gemfibrozil 1-O-Beta-Glucuronide exchange |
Gemfibrozil_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Mi |
N.A. |
n.a. |
Gemfibrozil M1 (4-Ring Hydroxylated Metabolite) exchange |
Gemfibrozil_mI[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Mi_Glc |
N.A. |
n.a. |
M1 Glucuronide exchange |
Gemfibrozil_mI_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Mii |
N.A. |
n.a. |
Gemfibrozil M2 (Benzyl Alcohol Metabolite) exchange |
Gemfibrozil_mII[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Mii_Glc |
N.A. |
n.a. |
M2 Glucuronide exchange |
Gemfibrozil_mII_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Miii |
N.A. |
n.a. |
Gemfibrozil M3 (Benzoic Acid Metabolite) exchange |
Gemfibrozil_mIII[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Miii_Glc |
N.A. |
n.a. |
M3 Glucuronide exchange |
Gemfibrozil_mIII_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Gtacetaminophen |
N.A. |
n.a. |
glucuronide-thiomethyl-acetaminophen conjugate exchange |
gtAcetaminophen[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin |
N.A. |
n.a. |
Hesperetin exchange |
Hesperetin[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_3_Glc |
N.A. |
n.a. |
Hesperetin 3-O-Glucuronide (Aglycone Of Hesperidin) exchange |
Hesperetin_3_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_3_S |
N.A. |
n.a. |
Hesperetin 3-O-Sulfate exchange |
Hesperetin_3_s[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_37_Diglc |
N.A. |
n.a. |
Hesperetin 3 7-Diglucuronide exchange |
Hesperetin_37_diglc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_3Glc_7S |
N.A. |
n.a. |
Hesperetin 3-O-Glucuronide 7-Sulfate exchange |
Hesperetin_3glc_7s[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_7_Glc |
N.A. |
n.a. |
Hesperetin 7-O-Glucuronide (Aglycone Of Hesperidin) exchange |
Hesperetin_7_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_7_S |
N.A. |
n.a. |
Hesperetin 7-O-Sulfate exchange |
Hesperetin_7_s[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_7Glc_3S |
N.A. |
n.a. |
Hesperetin 7-O-Glucuronide 3-Sulfate exchange |
Hesperetin_7glc_3s[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
Ibuprofen-S |
N.A. |
n.a. |
ibuprofen-S exchange |
ibuprofen-S[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
Ibuprofen Acyl Glucuronide |
N.A. |
n.a. |
ibuprofen acyl glucuronide exchange |
ibuprofen acyl glucuronide[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00328 |
Indomethacin |
N.A. |
n.a. |
Indomethacin exchange |
Indomethacin[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00328 |
Indomethacin_Glc |
N.A. |
n.a. |
Indomethacin Glucuronide exchange |
Indomethacin_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00224 |
Indinavir |
N.A. |
n.a. |
Indinavir exchange |
Indinavir[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00224 |
Indinavir_M1 |
N.A. |
n.a. |
Indanyl Glucuronide M1 exchange |
Indinavir_m1[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00951 |
Isoniazid |
N.A. |
n.a. |
Isoniazid exchange |
Isoniazid[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB09401 |
Isosorbide 5-Mononitrate |
N.A. |
n.a. |
Isosorbide 5-Mononitrate exchange |
Isosorbide 5-Mononitrate [e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB09401 |
Isosorbide 5-Mononitrate _Glc |
N.A. |
n.a. |
Isosorbide 5-Mononitrate 2-Beta-D-Glucuronide exchange |
Isosorbide 5-Mononitrate _glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01009 |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid) |
N.A. |
n.a. |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid) exchange |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01009 |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)_Glc |
N.A. |
n.a. |
Ketoprofen Glucuronide exchange |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00581 |
Lactulose |
N.A. |
n.a. |
Lactulose exchange |
Lactulose[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartan-E3174/ Losartan-M6 |
N.A. |
n.a. |
Losartan-E3174/ losartan-M6 exchange |
Losartan-E3174/ losartan-M6[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartan |
N.A. |
n.a. |
Losartan exchange |
Losartan[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartan1Gluc |
N.A. |
n.a. |
Losartan-N1-glucuronide exchange |
Losartan1gluc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartanm4 |
N.A. |
n.a. |
Losartan-M4 (glucuronide derivative) exchange |
Losartanm4[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartanm7 |
N.A. |
n.a. |
Losartan-N2-glucuronide / Losartan-M7 exchange |
Losartanm7[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
Midazolam |
N.A. |
n.a. |
Midazolam exchange |
Midazolam[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
Midazolam_Glc |
N.A. |
n.a. |
Midazolam Glucuronide exchange |
Midazolam_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
Midazolamglc |
N.A. |
n.a. |
Midazolam-glucuronide exchange |
Midazolamglc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB11716 |
Misonidazole |
N.A. |
n.a. |
Misonidazole exchange |
Misonidazole[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB11716 |
Misonidazole_Glc |
N.A. |
n.a. |
Misonidazole Glucuronide exchange |
Misonidazole_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00295 |
Morphine |
N.A. |
n.a. |
Morphine exchange |
Morphine[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00295 |
Morphine_3Glc |
N.A. |
n.a. |
Morphine 3-Glucuronide exchange |
Morphine_3glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00295 |
Morphine_6Glc |
N.A. |
n.a. |
Morphine 6-Glucuronide exchange |
Morphine_6glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
M-Tyramine |
N.A. |
n.a. |
Exchange of m-Tyramine |
mtym[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00916 |
Metronidazole |
N.A. |
n.a. |
Metronidazole exchange |
Metronidazole[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00916 |
Metronidazole_Glc |
N.A. |
n.a. |
Metronidazole Beta-D-Glucuronide exchange |
Metronidazole_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB03783 |
N-Hydroxylated Phenacetin |
N.A. |
n.a. |
N-Hydroxylated Phenacetin exchange |
N-Hydroxylated Phenacetin[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB03783 |
N-Hydroxylated Phenacetin_Glc |
N.A. |
n.a. |
N-Hydroxylated Phenacetin Glucuronide exchange |
N-Hydroxylated Phenacetin_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00446 |
Nchloramphenicol |
N.A. |
n.a. |
Nitrosochloramphenicol exchange |
nChloramphenicol[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Neoprontosilosil |
N.A. |
n.a. |
Neoprontosil exchange |
NeoProntosilosil[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00401 |
Nisoldipine (M5) |
N.A. |
n.a. |
Nisoldipine (M5) exchange |
Nisoldipine (M5)[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00401 |
Nisoldipine (M5)_Glc |
N.A. |
n.a. |
Nisoldipine (M5) Glucuronide exchange |
Nisoldipine (M5)_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Norverapamil |
N.A. |
n.a. |
Norverapamil exchange |
Norverapamil[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Norverapamil_Glc |
N.A. |
n.a. |
Norverapamil Glucuronide exchange |
Norverapamil_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01595 |
Nitrazepam, Benzalin, Neozepam |
N.A. |
n.a. |
Nitrazepam Benzalin Neozepam exchange |
Nitrazepam, Benzalin, Neozepam[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00674 |
Odsm_Egalantamine |
N.A. |
n.a. |
O-Desmethylepigalantamine exchange |
odsm_eGalantamine[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00674 |
Odsm_Egalantamine_Glc |
N.A. |
n.a. |
O-Desmethylepigalantamine Glucuronide exchange |
odsm_eGalantamine_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00674 |
Odsm_Galantamine |
N.A. |
n.a. |
O-Desmethylgalantamine exchange |
odsm_Galantamine[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00674 |
Odsm_Galantamine_Glc |
N.A. |
n.a. |
O-Desmethylgalantamine Glucuronide exchange |
odsm_Galantamine_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB06414 |
Etravarine Monohydroxylated (M1, M2, M3) |
N.A. |
n.a. |
Etravarine Monohydroxylated (M1 M2 M3) exchange |
Etravarine Monohydroxylated (M1, M2, M3)[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB06414 |
Etravarine Monohydroxylated (M1, M2, M3)_Glc |
N.A. |
n.a. |
Etravarine Monohydroxylated Glucuronide (M7) exchange |
Etravarine Monohydroxylated (M1, M2, M3)_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01174 |
P-Hydroxyphenobarbital |
N.A. |
n.a. |
P-Hydroxyphenobarbital exchange |
P-Hydroxyphenobarbital[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01174 |
P-Hydroxyphenobarbital_Glc |
N.A. |
n.a. |
Phenobarbital O-Glucuronide exchange |
P-Hydroxyphenobarbital_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01250 |
Olsalazine |
N.A. |
n.a. |
Olsalazine exchange |
Olsalazine[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
P-Cresol |
N.A. |
n.a. |
P-Cresol Exchange |
p-Cresol[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
3-(3-Hydroxyphenyl)Propionate |
N.A. |
n.a. |
3-(3-Hydroxyphenyl)Propionate exchange |
3-(3-Hydroxyphenyl)Propionate[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
3-(3-Hydroxyphenyl)Propionate_Glc |
N.A. |
n.a. |
3-(3-hydroxyphenyl)propionate glucuronide exchange |
3-(3-Hydroxyphenyl)Propionate_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB03783 |
Phenacetin Glucuronide |
N.A. |
n.a. |
Phenacetin Glucuronide exchange |
Phenacetin Glucuronide[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01032 |
Probenecid |
N.A. |
n.a. |
Probenecid exchange |
Probenecid[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01032 |
Probenecid_Glc |
N.A. |
n.a. |
Probenecid Acyl Beta-D-Glucuronide exchange |
Probenecid_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Prontosil |
N.A. |
n.a. |
Prontosil exchange |
Prontosil[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Prontosil_Glc |
N.A. |
n.a. |
Prontosil Glucuronide exchange |
Prontosil_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00571 |
Propranolol |
N.A. |
n.a. |
Propranolol exchange |
Propranolol[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00571 |
Propranolol_Glc |
N.A. |
n.a. |
Propranolol Glucuronide exchange |
Propranolol_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00715 |
Paroxetine Mi |
N.A. |
n.a. |
Paroxetine Mi exchange |
Paroxetine Mi[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00715 |
Paroxetine Mi_Glc |
N.A. |
n.a. |
Paroxetine Mi Glucuronide exchange |
Paroxetine Mi_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00715 |
Paroxetine Mii |
N.A. |
n.a. |
Paroxetine Mii exchange |
Paroxetine MiI[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00715 |
Paroxetine Mii_Glc |
N.A. |
n.a. |
Paroxetine Mii Glucuronide exchange |
Paroxetine MiI_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB08860 |
Pitavasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
N.A. |
n.a. |
pitavastatin exchange |
pitavasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB08860 |
Pitavasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
N.A. |
n.a. |
pitavastatin-glucuronide exchange |
pitavasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00175 |
Pravasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
N.A. |
n.a. |
pravastatin exchange |
pravasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00175 |
Pravasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
N.A. |
n.a. |
pravastatin glucuronide exchange |
pravasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
R-6-Hydroxywarfarin |
N.A. |
n.a. |
R-6-Hydroxywarfarin exchange |
R-6-Hydroxywarfarin[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
R-6-Hydroxywarfarin_Glc |
N.A. |
n.a. |
R-6-Hydroxywarfarin Glucuronate exchange |
R-6-Hydroxywarfarin_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
R-7-Hydroxywarfarin |
N.A. |
n.a. |
R-7-Hydroxywarfarin exchange |
R-7-Hydroxywarfarin[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
R-7-Hydroxywarfarin_Glc |
N.A. |
n.a. |
R-7-Hydroxy Warfarin Glucuronate exchange |
R-7-Hydroxywarfarin_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
R-8-Hydroxywarfarin |
N.A. |
n.a. |
R-8-Hydroxywarfarin exchange |
R-8-Hydroxywarfarin[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
R-8-Hydroxywarfarin_Glc |
N.A. |
n.a. |
R-8-Hydroxywarfarin Glucuronate exchange |
R-8-Hydroxywarfarin_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB07159 |
R406 |
N.A. |
n.a. |
R406 exchange |
R406[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB07159 |
R406_Glc |
N.A. |
n.a. |
Lactam N-Glucuronide Of R406 exchange |
R406_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
R529 |
N.A. |
n.a. |
R529 exchange |
R529[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
R529_Glc |
N.A. |
n.a. |
Glucuronide R529 exchange |
R529_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB12010 |
R788 (Fostamatinib) |
N.A. |
n.a. |
R788 (Fostamatinib) exchange |
R788 (Fostamatinib)[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB08896 |
Regorafenib |
N.A. |
n.a. |
Regorafenib exchange |
Regorafenib[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB08896 |
Regorafenib_Glc |
N.A. |
n.a. |
Regorafenib-glucuronide exchange |
Regorafenib_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00912 |
Repaglinide |
N.A. |
n.a. |
Repaglinide exchange |
Repaglinide[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00912 |
Repaglinide_Glc |
N.A. |
n.a. |
Repaglinide Acyl-Beta-D-Glucuronide exchange |
Repaglinide_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Skf 104557 (N-Despropyl Ropinirole) |
N.A. |
n.a. |
SKF 104557 (N-Despropyl Ropinirole) exchange |
SKF 104557 (N-Despropyl Ropinirole)[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Skf 104557 (N-Despropyl Ropinirole)_Cb_Glc |
N.A. |
n.a. |
SKF 104557 Carbamyl Glucuronide exchange |
SKF 104557 (N-Despropyl Ropinirole)_cb_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Skf 96990 |
N.A. |
n.a. |
SKF 96990 exchange |
SKF 96990[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Skf 96990_Glc |
N.A. |
n.a. |
SKF 96990 Glucuronide exchange |
SKF 96990_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00268 |
Hydroxy Ropinirole |
N.A. |
n.a. |
Hydroxy Ropinirole exchange |
Hydroxy Ropinirole[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00268 |
Hydroxy Ropinirole_Glc |
N.A. |
n.a. |
SKF 89124 Glucuronide exchange |
Hydroxy Ropinirole_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01098 |
Rosuvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
N.A. |
n.a. |
rosuvastatin exchange |
rosuvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01098 |
Rosuvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
N.A. |
n.a. |
rosuvastatin-glucuronide exchange |
rosuvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
S-4-Hydroxywarfarin |
N.A. |
n.a. |
S-4-Hydroxywarfarin exchange |
S-4-Hydroxywarfarin[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
S-4-Hydroxywarfarin_Glc |
N.A. |
n.a. |
S-4-Hydroxywarfarin Glucuronate exchange |
S-4-Hydroxywarfarin_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
S-6-Hydroxywarfarin |
N.A. |
n.a. |
S-6-Hydroxywarfarin exchange |
S-6-Hydroxywarfarin[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
S-6-Hydroxywarfarin_Glc |
N.A. |
n.a. |
S-6-Hydroxywarfarin Glucuronate exchange |
S-6-Hydroxywarfarin_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00259 |
Sulfanilamide |
N.A. |
n.a. |
Sulfanilamide exchange |
Sulfanilamide[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Sb-611855 (Intermediate Of M3) |
N.A. |
n.a. |
Sb-611855 (Intermediate Of M3) exchange |
Sb-611855 (Intermediate Of M3)[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Sb_Y (Intermediate Of M4) |
N.A. |
n.a. |
Sb_Y (Intermediate Of M4) exchange |
Sb_Y (Intermediate Of M4)[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Sch 488128 |
N.A. |
n.a. |
SCH 488128 exchange |
SCH 488128[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Sch 57871 |
N.A. |
n.a. |
SCH 57871 exchange |
SCH 57871[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Sch 57871_Glc |
N.A. |
n.a. |
SCH 57871 Glucuronide exchange |
SCH 57871_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB06654 |
Nw 1689 (N-Dealkylated Safinamide) |
N.A. |
n.a. |
Nw 1689 (N-Dealkylated Safinamide) exchange |
Nw 1689 (N-Dealkylated Safinamide)[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB06654 |
Nw 1689 (N-Dealkylated Safinamide)_Glc |
N.A. |
n.a. |
Nw 1689 Acyl Glucuronide exchange |
Nw 1689 (N-Dealkylated Safinamide)_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB06147 |
Sulfathiazole |
N.A. |
n.a. |
Sulfathiazole exchange |
Sulfathiazole[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB06147 |
Sulfathiazole_Glc |
N.A. |
n.a. |
Sulfathiazole Glucuronide exchange |
Sulfathiazole_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00641 |
Simvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acyl-Glucuronide |
N.A. |
n.a. |
simvastatin-acyl-glucuronide exchange |
simvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acyl-glucuronide[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
2-Sulfamoylacetylphenol |
N.A. |
n.a. |
2-Sulfamoylacetylphenol exchange |
2-Sulfamoylacetylphenol[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
2-Sulfamoylacetylphenol_Glc |
N.A. |
n.a. |
2-Sulfamoylacetylphenol Glucuronide exchange |
2-Sulfamoylacetylphenol_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00641 |
Simvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Dihydroxy Acid Form |
N.A. |
n.a. |
simvastatin dihydroxy acid form exchange |
simvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin dihydroxy acid form[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00762 |
Sn-38 (Active Me1,2,4-Triaminobenzeneolite Of Irinotecan) |
N.A. |
n.a. |
SN-38 (active metabolite of irinotecan) exchange |
SN-38 (active me1,2,4-Triaminobenzeneolite of irinotecan)[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00762 |
Sn-38 (Active Me1,2,4-Triaminobenzeneolite Of Irinotecan)G |
N.A. |
n.a. |
SN38 glucuronide exchange |
SN-38 (active me1,2,4-Triaminobenzeneolite of irinotecan)g[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01138 |
Sulfinpyrazone |
N.A. |
n.a. |
Sulfinpyrazone exchange |
Sulfinpyrazone[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01138 |
Sulfinpyrazone_Glc |
N.A. |
n.a. |
Sulfinpyrazone Glucuronide exchange |
Sulfinpyrazone_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01138 |
Sulfinpyrazone_Sfn |
N.A. |
n.a. |
Sulfinpyrazone Sulfone exchange |
Sulfinpyrazone_sfn[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01138 |
Sulfinpyrazone_Sfn_Glc |
N.A. |
n.a. |
Sulfinpyrazone Sulfone Glucuronide exchange |
Sulfinpyrazone_sfn_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB11998 |
Sorivudine |
N.A. |
n.a. |
Sorivudine exchange |
Sorivudine[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00795 |
Sulfasalazine |
N.A. |
n.a. |
Sulfasalazine exchange |
Sulfasalazine[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01261 |
Sitagliptin |
N.A. |
n.a. |
Sitagliptin exchange |
Sitagliptin[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01261 |
Sitagliptin_M3 |
N.A. |
n.a. |
Sitagliptin M3 (Ether Glucuronide Conjugate Of A Hydroxylated Derivative) exchange |
Sitagliptin_m3[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01261 |
Sitagliptin_M4 |
N.A. |
n.a. |
Sitagliptin M4 (N-Carbomyl Glucuronide Conjugate) exchange |
Sitagliptin_m4[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00891 |
Sulfapyridine |
N.A. |
n.a. |
Sulfapyridine exchange |
Sulfapyridine[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
1,2,4-Triaminobenzene |
N.A. |
n.a. |
1 2 4-Triaminobenzene exchange |
1,2,4-Triaminobenzene[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid |
N.A. |
n.a. |
N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid exchange |
N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB01956 |
Taurine |
N.A. |
n.a. |
Taurine exchange |
Taurine[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB04348 |
Taurocholate |
N.A. |
n.a. |
Taurocholic acid exchange |
taurocholate[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB08833 |
Taurochenodeoxycholate |
N.A. |
n.a. |
taurochenodeoxycholate exchange |
Taurochenodeoxycholate[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00197 |
Troglitazone |
N.A. |
n.a. |
Troglitazone exchange |
Troglitazone[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00197 |
Troglitazone_Glc |
N.A. |
n.a. |
Troglitazone Glucuronide exchange |
Troglitazone_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Thsacetaminophen |
N.A. |
n.a. |
thiomethyl-sulphoxide-conjugate-acetaminophen exchange |
thsAcetaminophen[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid |
N.A. |
n.a. |
Tolfenamic Acid exchange |
Tolfenamic Acid[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_1A |
N.A. |
n.a. |
Tolfenamic Acid 1A exchange |
Tolfenamic Acid_1a[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_1B |
N.A. |
n.a. |
Tolfenamic Acid 1B exchange |
Tolfenamic Acid_1b[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_1X |
N.A. |
n.a. |
Tolfenamic Acid 1X exchange |
Tolfenamic Acid_1x[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_2 |
N.A. |
n.a. |
Tolfenamic Acid 2 exchange |
Tolfenamic Acid_2[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_2A |
N.A. |
n.a. |
Tolfenamic Acid 2A exchange |
Tolfenamic Acid_2a[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_3 |
N.A. |
n.a. |
Tolfenamic Acid 3 exchange |
Tolfenamic Acid_3[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_4 |
N.A. |
n.a. |
Tolfenamic Acid 4 exchange |
Tolfenamic Acid_4[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M1 |
N.A. |
n.a. |
N-(2-Hydroxymethyl-3-Chlorophenyl)-Anthranilic Acid exchange |
Tolfenamic Acid_m1[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M2 |
N.A. |
n.a. |
N-(2-Hydroxymethyl-3-Chloro-4-Hydroxyphenyl)-Anthranilic Acid exchange |
Tolfenamic Acid_m2[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M3 |
N.A. |
n.a. |
N-(2-Formyl-3-Chlorophenyl) Anthranilic Acid exchange |
Tolfenamic Acid_m3[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M4 |
N.A. |
n.a. |
N-(2-Methyl-3- Chloro-4-Hydroxyphenyl)-Anthranilic Acid exchange |
Tolfenamic Acid_m4[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_M4A |
N.A. |
n.a. |
Tolfenamic Acid M4A exchange |
Tolfenamic Acid_m4a[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M5 |
N.A. |
n.a. |
N-(2-Methyl-3-Chloro-5-Hydroxyphenyl)-Anthranilic Acid exchange |
Tolfenamic Acid_m5[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_M5A |
N.A. |
n.a. |
Tolfenamic Acid M5A exchange |
Tolfenamic Acid_m5a[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_M5B |
N.A. |
n.a. |
Tolfenamic Acid M5B exchange |
Tolfenamic Acid_m5b[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M6 |
N.A. |
n.a. |
N-(2-Carboxy-3-Chlorophenyl)-Anthranilic Acid exchange |
Tolfenamic Acid_m6[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M9 |
N.A. |
n.a. |
N-(2-Methyl-3-Chloro-4-Metoxyphenyl)-Anthranilic Acid exchange |
Tolfenamic Acid_m9[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00966 |
Telmisartan |
N.A. |
n.a. |
Telmisartan exchange |
Telmisartan[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00966 |
Telmisartan_Glc |
N.A. |
n.a. |
Telmisartan Glucuronide exchange |
Telmisartan_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Tmacetaminophen |
N.A. |
n.a. |
thiomethyl-conjugate-acetaminophen exchange |
tmAcetaminophen[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone? |
N.A. |
n.a. |
Tolcapone? exchange |
Tolcapone?[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Ac |
N.A. |
n.a. |
Tolcapone N-Acetyl Amino Metabolite exchange |
Tolcapone?_ac[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Ac_Glc |
N.A. |
n.a. |
Tolcapone N-Acetyl Amino Glucuronide exchange |
Tolcapone?_ac_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Am |
N.A. |
n.a. |
Tolcapone Amine Derivative exchange |
Tolcapone?_am[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Am_Glc |
N.A. |
n.a. |
Tolcapone Amine Glucuronide exchange |
Tolcapone?_am_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Glc |
N.A. |
n.a. |
Tolcapone 3-Beta-D-Glucuronide exchange |
Tolcapone?_glc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB12449 |
Tempol 1-O-Glucuronide And 4-O-Glucoside |
N.A. |
n.a. |
Tempol 1-O-Glucuronide And 4-O-Glucoside exchange |
Tempol 1-O-Glucuronide And 4-O-Glucoside[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB12449 |
Tempol 4-O-Glucoside |
N.A. |
n.a. |
Tempol 4-O-Glucoside exchange |
Tempol 4-O-Glucoside[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB12449 |
Tempol 4-O-Glucosidelc |
N.A. |
n.a. |
Tempol 4-O-Glucuronide exchange |
Tempol 4-O-Glucosidelc[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB12449 |
Tempol Hydroxylamine |
N.A. |
n.a. |
Tempol Hydroxylamine exchange |
Tempol Hydroxylamine[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Thiomethyl-Sulphoxide-Acetaminophen-Glucuronide |
N.A. |
n.a. |
thiomethyl-sulphoxide-acetaminophen-glucuronide exchange |
thiomethyl-sulphoxide-acetaminophen-glucuronide[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB08841 |
Tyramine |
N.A. |
n.a. |
Exchange of Tyramine |
tym[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00135 |
L-Tyrosine |
N.A. |
n.a. |
Exchange of L-Tyrosine |
tyr_L[e] <=> |
Exchange/demand reaction |
Transport |
Exchange/demand reaction |
n.a. |
n.a. |
PMID: 36658342 |
| DB00973 |
Ezetimibe_Glc |
Ezetimibe |
UidAc |
Ezetimibe Glucuronide beta-glucuronidase |
Ezetimibe_glc[c] + h2o[c] -> Ezetimibe[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00973 |
Ezetimibe_Glc |
Ezetimibe |
UidAe |
Ezetimibe Glucuronide beta-glucuronidase extracellular |
Ezetimibe_glc[e] + h2o[e] -> Ezetimibe[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00973 |
Ezetimibe_Glc |
Ezetimibe |
UidAe |
Ezetimibe Glucuronide beta-glucuronidase extracellular, periplasmatic |
Ezetimibe_glc[p] + h2o[p] -> Ezetimibe[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00973 |
Ezetimibe_Glc |
Ezetimibe_Glc |
UidABC |
Predicted glucuronide ABC transporter Ezetimibe Glucuronide |
atp[c] + Ezetimibe_glc[e] + h2o[c] -> adp[c] + Ezetimibe_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00973 |
Ezetimibe_Glc |
Ezetimibe_Glc |
UidP |
Transport of D-Glucuronate Ezetimibe Glucuronide |
Ezetimibe_glc[e] -> Ezetimibe_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00973 |
Ezetimibe_Glc |
Ezetimibe_Glc |
UidB |
Glucuronate transport in via proton symport Ezetimibe Glucuronide |
Ezetimibe_glc[e] + h[e] -> Ezetimibe_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00973 |
Ezetimibe_Glc |
Ezetimibe_Glc |
UidB |
Glucuronate transport in via proton symport Ezetimibe Glucuronide, periplasmatic |
Ezetimibe_glc[p] + h[p] -> Ezetimibe_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00973 |
Ezetimibe_Glc |
Ezetimibe_Glc |
n.a. |
Ezetimibe Glucuronide diffusion extracellular to periplasm |
Ezetimibe_glc[e] <=> Ezetimibe_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00973 |
Ezetimibe |
Ezetimibe |
n.a. |
beta-glucuronidase reaction product export Ezetimibe |
Ezetimibe[c] -> Ezetimibe[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00973 |
Ezetimibe |
Ezetimibe |
n.a. |
beta-glucuronidase reaction product export Ezetimibe, periplasmatic |
Ezetimibe[c] -> Ezetimibe[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00973 |
Ezetimibe |
Ezetimibe |
n.a. |
Ezetimibe diffusion extracellular to periplasm |
Ezetimibe[e] <=> Ezetimibe[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
5-Fluorocytosine |
5-Fluorouracil |
CodA |
Cytosine Deaminase (5-Fluorocytosine) |
5-Fluorocytosine[c] + h[c] + h2o[c] -> nh4[c] + 5-Fluorouracil[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 26261286 |
| n.a. |
5-Fluorocytosine |
5-Fluorouracil |
eCodA |
Cytosine Deaminase (5-Fluorocytosine) |
5-Fluorocytosine[e] + h[e] + h2o[e] -> nh4[e] + 5-Fluorouracil[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 26261286 |
| n.a. |
5-Fluorocytosine |
5-Fluorocytosine |
CodB |
5-fluorocytosine Transport via Faciliated Diffusion |
5-Fluorocytosine[e] <=> 5-Fluorocytosine[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
UidAc |
fluvstatin-glucuronide beta-glucuronidase |
fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[c] + h2o[c] -> fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01095 |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
UidAe |
fluvstatin-glucuronide beta-glucuronidase extracellular |
fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[e] + h2o[e] -> fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01095 |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
UidAe |
fluvstatin-glucuronide beta-glucuronidase extracellular, periplasmatic |
fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[p] + h2o[p] -> fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01095 |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
UidABC |
Predicted glucuronide ABC transporter fluvstatin-glucuronide |
atp[c] + fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[e] + h2o[c] -> adp[c] + fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
UidP |
Transport of D-Glucuronate fluvstatin-glucuronide |
fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[e] -> fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
UidB |
Glucuronate transport in via proton symport fluvstatin-glucuronide |
fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[e] + h[e] -> fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
UidB |
Glucuronate transport in via proton symport fluvstatin-glucuronide, periplasmatic |
fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[p] + h[p] -> fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
n.a. |
fluvstatin-glucuronide diffusion extracellular to periplasm |
fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[e] <=> fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
n.a. |
beta-glucuronidase reaction product export fluvastatin |
fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[c] -> fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
n.a. |
beta-glucuronidase reaction product export fluvastatin, periplasmatic |
fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[c] -> fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintetglu |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintet |
UidAc |
des-isopropyl-dihydro-fluvastatin-tetranor-glucuronide beta-glucuronidase |
fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintetglu[c] + h2o[c] -> fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintet[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01095 |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintetglu |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintet |
UidAe |
des-isopropyl-dihydro-fluvastatin-tetranor-glucuronide beta-glucuronidase extracellular |
fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintetglu[e] + h2o[e] -> fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintet[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01095 |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintetglu |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintet |
UidAe |
des-isopropyl-dihydro-fluvastatin-tetranor-glucuronide beta-glucuronidase extracellular, periplasmatic |
fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintetglu[p] + h2o[p] -> fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintet[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01095 |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintetglu |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintetglu |
UidABC |
Predicted glucuronide ABC transporter des-isopropyl-dihydro-fluvastatin-tetranor-glucuronide |
atp[c] + fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintetglu[e] + h2o[c] -> adp[c] + fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintetglu[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintetglu |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintetglu |
UidP |
Transport of D-Glucuronate des-isopropyl-dihydro-fluvastatin-tetranor-glucuronide |
fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintetglu[e] -> fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintetglu[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintetglu |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintetglu |
UidB |
Glucuronate transport in via proton symport des-isopropyl-dihydro-fluvastatin-tetranor-glucuronide |
fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintetglu[e] + h[e] -> fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintetglu[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintetglu |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintetglu |
UidB |
Glucuronate transport in via proton symport des-isopropyl-dihydro-fluvastatin-tetranor-glucuronide, periplasmatic |
fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintetglu[p] + h[p] -> fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintetglu[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintetglu |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintetglu |
n.a. |
des-isopropyl-dihydro-fluvastatin-tetranor-glucuronide diffusion extracellular to periplasm |
fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintetglu[e] <=> fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintetglu[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintet |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintet |
n.a. |
beta-glucuronidase reaction product export des-isopropyl-dihydro-fluvastatin-tetranor |
fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintet[c] -> fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintet[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintet |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintet |
n.a. |
beta-glucuronidase reaction product export des-isopropyl-dihydro-fluvastatin-tetranor, periplasmatic |
fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintet[c] -> fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintet[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintet |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintet |
n.a. |
des-isopropyl-dihydro-fluvastatin-tetranor diffusion extracellular to periplasm |
fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintet[e] <=> fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidintet[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01095 |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
Fluvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
n.a. |
fluvastatin diffusion extracellular to periplasm |
fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[e] <=> fluvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00581 |
Lactulose |
N.A. |
bGal |
B-galactosidase (Lactulose) |
h2o[c] + Lactulose[c] -> gal[c] + fru[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 25340538 |
| DB00581 |
Lactulose |
N.A. |
bGale |
B-Galactosidase (Lactulose), Extracellular |
h2o[e] + Lactulose[e] -> gal[e] + fru[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 25340538 |
| DB11735 |
Galactose |
N.A. |
LacY |
Galactose Transport (Uniport) |
gal[e] <=> gal[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Glycinecochenodeoxycholate |
Chenodeoxycholate |
BSH |
Glycochenodeoxycholate hydrolysis by bile salt hydrolase (EC 3.5.1.24) |
Glycinecochenodeoxycholate[e] + h2o[e] -> chenodeoxyCholate[e] + Glycine[e] + h[e] |
Bile acid metabolism |
Metabolism |
Experimental Subsystems |
Bile acid metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Glycinecocholate |
Cholate |
BSH |
Glycocholate hydrolysis by bile salt hydrolase (EC 3.5.1.24) |
Glycinecocholate[e] + h2o[e] -> Cholate[e] + Glycine[e] + h[e] |
Bile acid metabolism |
Metabolism |
Experimental Subsystems |
Bile acid metabolism |
n.a. |
PMID: 36658342 |
| DB00316 |
Glucuronide-Conjugate Of 3-Methoxy-Acetaminophen |
3-Methoxy-Acetaminophen |
UidAc |
glucuronide-conjugate of 3-methoxy-acetaminophen beta-glucuronidase |
glucuronide-conjugate of 3-methoxy-acetaminophen[c] + h2o[c] + amet[c] -> 3-methoxy-acetaminophen[c] + glcur[c] + h[c] + ahcys[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00316 |
Glucuronide-Conjugate Of 3-Methoxy-Acetaminophen |
3-Methoxy-Acetaminophen |
UidAe |
glucuronide-conjugate of 3-methoxy-acetaminophen beta-glucuronidase extracellular |
glucuronide-conjugate of 3-methoxy-acetaminophen[e] + h2o[e] + amet[c] -> 3-methoxy-acetaminophen[e] + glcur[e] + h[e] + ahcys[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00316 |
Glucuronide-Conjugate Of 3-Methoxy-Acetaminophen |
3-Methoxy-Acetaminophen |
UidAe |
glucuronide-conjugate of 3-methoxy-acetaminophen beta-glucuronidase extracellular, periplasmatic |
amet[c] + glucuronide-conjugate of 3-methoxy-acetaminophen[p] + h2o[p] -> ahcys[c] + 3-methoxy-acetaminophen[p] + glcur[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00316 |
Glucuronide-Conjugate Of 3-Methoxy-Acetaminophen |
Glucuronide-Conjugate Of 3-Methoxy-Acetaminophen |
UidABC |
Predicted glucuronide ABC transporter glucuronide-conjugate of 3-methoxy-acetaminophen |
atp[c] + glucuronide-conjugate of 3-methoxy-acetaminophen[e] + h2o[c] -> adp[c] + glucuronide-conjugate of 3-methoxy-acetaminophen[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Glucuronide-Conjugate Of 3-Methoxy-Acetaminophen |
Glucuronide-Conjugate Of 3-Methoxy-Acetaminophen |
UidP |
Transport of D-Glucuronate glucuronide-conjugate of 3-methoxy-acetaminophen |
glucuronide-conjugate of 3-methoxy-acetaminophen[e] -> glucuronide-conjugate of 3-methoxy-acetaminophen[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Glucuronide-Conjugate Of 3-Methoxy-Acetaminophen |
Glucuronide-Conjugate Of 3-Methoxy-Acetaminophen |
UidB |
Glucuronate transport in via proton symport glucuronide-conjugate of 3-methoxy-acetaminophen |
glucuronide-conjugate of 3-methoxy-acetaminophen[e] + h[e] -> glucuronide-conjugate of 3-methoxy-acetaminophen[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Glucuronide-Conjugate Of 3-Methoxy-Acetaminophen |
Glucuronide-Conjugate Of 3-Methoxy-Acetaminophen |
UidB |
Glucuronate transport in via proton symport glucuronide-conjugate of 3-methoxy-acetaminophen, periplasmatic |
glucuronide-conjugate of 3-methoxy-acetaminophen[p] + h[p] -> glucuronide-conjugate of 3-methoxy-acetaminophen[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Glucuronide-Conjugate Of 3-Methoxy-Acetaminophen |
Glucuronide-Conjugate Of 3-Methoxy-Acetaminophen |
n.a. |
glucuronide-conjugate of 3-methoxy-acetaminophen diffusion extracellular to periplasm |
glucuronide-conjugate of 3-methoxy-acetaminophen[e] <=> glucuronide-conjugate of 3-methoxy-acetaminophen[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00674 |
Galantamine_Glc |
Galantamine |
UidAc |
Galantamine Glucuronide beta-glucuronidase |
Galantamine_glc[c] + h2o[c] -> Galantamine[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00674 |
Galantamine_Glc |
Galantamine |
UidAe |
Galantamine Glucuronide beta-glucuronidase extracellular |
Galantamine_glc[e] + h2o[e] -> Galantamine[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00674 |
Galantamine_Glc |
Galantamine |
UidAe |
Galantamine Glucuronide beta-glucuronidase extracellular, periplasmatic |
Galantamine_glc[p] + h2o[p] -> glcur[p] + Galantamine[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00674 |
Galantamine_Glc |
Galantamine_Glc |
UidABC |
Predicted glucuronide ABC transporter Galantamine Glucuronide |
atp[c] + Galantamine_glc[e] + h2o[c] -> adp[c] + Galantamine_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00674 |
Galantamine_Glc |
Galantamine_Glc |
UidP |
Transport of D-Glucuronate Galantamine Glucuronide |
Galantamine_glc[e] -> Galantamine_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00674 |
Galantamine_Glc |
Galantamine_Glc |
UidB |
Glucuronate transport in via proton symport Galantamine Glucuronide |
Galantamine_glc[e] + h[e] -> Galantamine_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00674 |
Galantamine_Glc |
Galantamine_Glc |
UidB |
Glucuronate transport in via proton symport Galantamine Glucuronide, periplasmatic |
Galantamine_glc[p] + h[p] -> Galantamine_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00674 |
Galantamine_Glc |
Galantamine_Glc |
n.a. |
Galantamine Glucuronide diffusion extracellular to periplasm |
Galantamine_glc[e] <=> Galantamine_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00674 |
Galantamine |
Galantamine |
n.a. |
beta-glucuronidase reaction product export Galantamine |
Galantamine[c] -> Galantamine[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00674 |
Galantamine |
Galantamine |
n.a. |
beta-glucuronidase reaction product export Galantamine, periplasmatic |
Galantamine[c] -> Galantamine[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00674 |
Galantamine |
Galantamine |
n.a. |
Galantamine diffusion extracellular to periplasm |
Galantamine[e] <=> Galantamine[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Glc |
Gemfibrozil |
UidAc |
Gemfibrozil 1-O-Beta-Glucuronide beta-glucuronidase |
Gemfibrozil_glc[c] + h2o[c] -> Gemfibrozil[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Glc |
Gemfibrozil |
UidAe |
Gemfibrozil 1-O-Beta-Glucuronide beta-glucuronidase extracellular |
Gemfibrozil_glc[e] + h2o[e] -> Gemfibrozil[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Glc |
Gemfibrozil |
UidAe |
Gemfibrozil 1-O-Beta-Glucuronide beta-glucuronidase extracellular, periplasmatic |
Gemfibrozil_glc[p] + h2o[p] -> glcur[p] + Gemfibrozil[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Glc |
Gemfibrozil_Glc |
UidABC |
Predicted glucuronide ABC transporter Gemfibrozil 1-O-Beta-Glucuronide |
atp[c] + Gemfibrozil_glc[e] + h2o[c] -> adp[c] + Gemfibrozil_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Glc |
Gemfibrozil_Glc |
UidP |
Transport of D-Glucuronate Gemfibrozil 1-O-Beta-Glucuronide |
Gemfibrozil_glc[e] -> Gemfibrozil_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Glc |
Gemfibrozil_Glc |
UidB |
Glucuronate transport in via proton symport Gemfibrozil 1-O-Beta-Glucuronide |
Gemfibrozil_glc[e] + h[e] -> Gemfibrozil_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Glc |
Gemfibrozil_Glc |
UidB |
Glucuronate transport in via proton symport Gemfibrozil 1-O-Beta-Glucuronide, periplasmatic |
Gemfibrozil_glc[p] + h[p] -> Gemfibrozil_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Glc |
Gemfibrozil_Glc |
n.a. |
Gemfibrozil 1-O-Beta-Glucuronide diffusion extracellular to periplasm |
Gemfibrozil_glc[e] <=> Gemfibrozil_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Mi_Glc |
Gemfibrozil_Mi |
UidAc |
M1 Glucuronide beta-glucuronidase |
Gemfibrozil_mI_glc[c] + h2o[c] -> Gemfibrozil_mI[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Mi_Glc |
Gemfibrozil_Mi |
UidAe |
M1 Glucuronide beta-glucuronidase extracellular |
Gemfibrozil_mI_glc[e] + h2o[e] -> Gemfibrozil_mI[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Mi_Glc |
Gemfibrozil_Mi |
UidAe |
M1 Glucuronide beta-glucuronidase extracellular, periplasmatic |
Gemfibrozil_mI_glc[p] + h2o[p] -> glcur[p] + Gemfibrozil_mI[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Mi_Glc |
Gemfibrozil_Mi_Glc |
UidABC |
Predicted glucuronide ABC transporter M1 Glucuronide |
atp[c] + Gemfibrozil_mI_glc[e] + h2o[c] -> adp[c] + Gemfibrozil_mI_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Mi_Glc |
Gemfibrozil_Mi_Glc |
UidP |
Transport of D-Glucuronate M1 Glucuronide |
Gemfibrozil_mI_glc[e] -> Gemfibrozil_mI_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Mi_Glc |
Gemfibrozil_Mi_Glc |
UidB |
Glucuronate transport in via proton symport M1 Glucuronide |
Gemfibrozil_mI_glc[e] + h[e] -> Gemfibrozil_mI_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Mi_Glc |
Gemfibrozil_Mi_Glc |
UidB |
Glucuronate transport in via proton symport M1 Glucuronide, periplasmatic |
Gemfibrozil_mI_glc[p] + h[p] -> Gemfibrozil_mI_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Mi_Glc |
Gemfibrozil_Mi_Glc |
n.a. |
M1 Glucuronide diffusion extracellular to periplasm |
Gemfibrozil_mI_glc[e] <=> Gemfibrozil_mI_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Mii_Glc |
Gemfibrozil_Mii |
UidAc |
M2 Glucuronide beta-glucuronidase |
Gemfibrozil_mII_glc[c] + h2o[c] -> Gemfibrozil_mII[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Mii_Glc |
Gemfibrozil_Mii |
UidAe |
M2 Glucuronide beta-glucuronidase extracellular |
Gemfibrozil_mII_glc[e] + h2o[e] -> Gemfibrozil_mII[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Mii_Glc |
Gemfibrozil_Mii |
UidAe |
M2 Glucuronide beta-glucuronidase extracellular, periplasmatic |
Gemfibrozil_mII_glc[p] + h2o[p] -> glcur[p] + Gemfibrozil_mII[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Mii_Glc |
Gemfibrozil_Mii_Glc |
UidABC |
Predicted glucuronide ABC transporter M2 Glucuronide |
atp[c] + Gemfibrozil_mII_glc[e] + h2o[c] -> adp[c] + Gemfibrozil_mII_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Mii_Glc |
Gemfibrozil_Mii_Glc |
UidP |
Transport of D-Glucuronate M2 Glucuronide |
Gemfibrozil_mII_glc[e] -> Gemfibrozil_mII_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Mii_Glc |
Gemfibrozil_Mii_Glc |
UidB |
Glucuronate transport in via proton symport M2 Glucuronide |
Gemfibrozil_mII_glc[e] + h[e] -> Gemfibrozil_mII_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Mii_Glc |
Gemfibrozil_Mii_Glc |
UidB |
Glucuronate transport in via proton symport M2 Glucuronide, periplasmatic |
Gemfibrozil_mII_glc[p] + h[p] -> Gemfibrozil_mII_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Mii_Glc |
Gemfibrozil_Mii_Glc |
n.a. |
M2 Glucuronide diffusion extracellular to periplasm |
Gemfibrozil_mII_glc[e] <=> Gemfibrozil_mII_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Miii_Glc |
Gemfibrozil_Miii |
UidAc |
M3 Glucuronide beta-glucuronidase |
Gemfibrozil_mIII_glc[c] + h2o[c] -> Gemfibrozil_mIII[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Miii_Glc |
Gemfibrozil_Miii |
UidAe |
M3 Glucuronide beta-glucuronidase extracellular |
Gemfibrozil_mIII_glc[e] + h2o[e] -> Gemfibrozil_mIII[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Miii_Glc |
Gemfibrozil_Miii |
UidAe |
M3 Glucuronide beta-glucuronidase extracellular, periplasmatic |
Gemfibrozil_mIII_glc[p] + h2o[p] -> glcur[p] + Gemfibrozil_mIII[p] + h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Miii_Glc |
Gemfibrozil_Miii_Glc |
UidABC |
Predicted glucuronide ABC transporter M3 Glucuronide |
atp[c] + Gemfibrozil_mIII_glc[e] + h2o[c] -> adp[c] + Gemfibrozil_mIII_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Miii_Glc |
Gemfibrozil_Miii_Glc |
UidP |
Transport of D-Glucuronate M3 Glucuronide |
Gemfibrozil_mIII_glc[e] -> Gemfibrozil_mIII_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Miii_Glc |
Gemfibrozil_Miii_Glc |
UidB |
Glucuronate transport in via proton symport M3 Glucuronide |
Gemfibrozil_mIII_glc[e] + h[e] -> Gemfibrozil_mIII_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Miii_Glc |
Gemfibrozil_Miii_Glc |
UidB |
Glucuronate transport in via proton symport M3 Glucuronide, periplasmatic |
Gemfibrozil_mIII_glc[p] + h[p] -> Gemfibrozil_mIII_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Miii_Glc |
Gemfibrozil_Miii_Glc |
n.a. |
M3 Glucuronide diffusion extracellular to periplasm |
Gemfibrozil_mIII_glc[e] <=> Gemfibrozil_mIII_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Miii |
Gemfibrozil_Miii |
n.a. |
beta-glucuronidase reaction product export Gemfibrozil M3 (Benzoic Acid Metabolite) |
Gemfibrozil_mIII[c] -> Gemfibrozil_mIII[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Miii |
Gemfibrozil_Miii |
n.a. |
beta-glucuronidase reaction product export Gemfibrozil M3 (Benzoic Acid Metabolite), periplasmatic |
Gemfibrozil_mIII[c] -> Gemfibrozil_mIII[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Miii |
Gemfibrozil_Miii |
n.a. |
Gemfibrozil M3 (Benzoic Acid Metabolite) diffusion extracellular to periplasm |
Gemfibrozil_mIII[e] <=> Gemfibrozil_mIII[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Mii |
Gemfibrozil_Mii |
n.a. |
beta-glucuronidase reaction product export Gemfibrozil M2 (Benzyl Alcohol Metabolite) |
Gemfibrozil_mII[c] -> Gemfibrozil_mII[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Mii |
Gemfibrozil_Mii |
n.a. |
beta-glucuronidase reaction product export Gemfibrozil M2 (Benzyl Alcohol Metabolite), periplasmatic |
Gemfibrozil_mII[c] -> Gemfibrozil_mII[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Mii |
Gemfibrozil_Mii |
n.a. |
Gemfibrozil M2 (Benzyl Alcohol Metabolite) diffusion extracellular to periplasm |
Gemfibrozil_mII[e] <=> Gemfibrozil_mII[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Mi |
Gemfibrozil_Mi |
n.a. |
beta-glucuronidase reaction product export Gemfibrozil M1 (4-Ring Hydroxylated Metabolite) |
Gemfibrozil_mI[c] -> Gemfibrozil_mI[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Mi |
Gemfibrozil_Mi |
n.a. |
beta-glucuronidase reaction product export Gemfibrozil M1 (4-Ring Hydroxylated Metabolite), periplasmatic |
Gemfibrozil_mI[c] -> Gemfibrozil_mI[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil_Mi |
Gemfibrozil_Mi |
n.a. |
Gemfibrozil M1 (4-Ring Hydroxylated Metabolite) diffusion extracellular to periplasm |
Gemfibrozil_mI[e] <=> Gemfibrozil_mI[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil |
Gemfibrozil |
n.a. |
beta-glucuronidase reaction product export Gemfibrozil |
Gemfibrozil[c] -> Gemfibrozil[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil |
Gemfibrozil |
n.a. |
beta-glucuronidase reaction product export Gemfibrozil, periplasmatic |
Gemfibrozil[c] -> Gemfibrozil[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01241 |
Gemfibrozil |
Gemfibrozil |
n.a. |
Gemfibrozil diffusion extracellular to periplasm |
Gemfibrozil[e] <=> Gemfibrozil[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Gtacetaminophen |
Tmacetaminophen |
UidAc |
glucuronide-thiomethyl-acetaminophen conjugate beta-glucuronidase |
gtAcetaminophen[c] + h2o[c] -> tmAcetaminophen[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00316 |
Gtacetaminophen |
Tmacetaminophen |
UidAe |
glucuronide-thiomethyl-acetaminophen conjugate beta-glucuronidase extracellular |
gtAcetaminophen[e] + h2o[e] -> tmAcetaminophen[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00316 |
Gtacetaminophen |
Tmacetaminophen |
UidAe |
glucuronide-thiomethyl-acetaminophen conjugate beta-glucuronidase extracellular, periplasmatic |
gtAcetaminophen[p] + h2o[p] -> glcur[p] + tmAcetaminophen[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00316 |
Gtacetaminophen |
Gtacetaminophen |
UidABC |
Predicted glucuronide ABC transporter glucuronide-thiomethyl-acetaminophen conjugate |
atp[c] + gtAcetaminophen[e] + h2o[c] -> adp[c] + gtAcetaminophen[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Gtacetaminophen |
Gtacetaminophen |
UidP |
Transport of D-Glucuronate glucuronide-thiomethyl-acetaminophen conjugate |
gtAcetaminophen[e] -> gtAcetaminophen[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Gtacetaminophen |
Gtacetaminophen |
UidB |
Glucuronate transport in via proton symport glucuronide-thiomethyl-acetaminophen conjugate |
gtAcetaminophen[e] + h[e] -> gtAcetaminophen[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Gtacetaminophen |
Gtacetaminophen |
UidB |
Glucuronate transport in via proton symport glucuronide-thiomethyl-acetaminophen conjugate, periplasmatic |
gtAcetaminophen[p] + h[p] -> gtAcetaminophen[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Gtacetaminophen |
Gtacetaminophen |
n.a. |
glucuronide-thiomethyl-acetaminophen conjugate diffusion extracellular to periplasm |
gtAcetaminophen[e] <=> gtAcetaminophen[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Hydroxyphenylacetate |
N.A. |
Hpd |
Hydroxyphenylacetate transport in via proton symporter |
4hphac[e] + h[e] <=> 4hphac[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_3_Glc |
Hesperetin |
UidAc |
Hesperetin 3-O-Glucuronide (Aglycone Of Hesperidin) beta-glucuronidase |
Hesperetin_3_glc[c] + h2o[c] -> Hesperetin[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_3_Glc |
Hesperetin |
UidAe |
Hesperetin 3-O-Glucuronide (Aglycone Of Hesperidin) beta-glucuronidase extracellular |
Hesperetin_3_glc[e] + h2o[e] -> Hesperetin[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_3_Glc |
Hesperetin |
UidAe |
Hesperetin 3-O-Glucuronide (Aglycone Of Hesperidin) beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Hesperetin_3_glc[p] -> glcur[p] + Hesperetin[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_3_Glc |
Hesperetin_3_Glc |
UidABC |
Predicted glucuronide ABC transporter Hesperetin 3-O-Glucuronide (Aglycone Of Hesperidin) |
atp[c] + Hesperetin_3_glc[e] + h2o[c] -> adp[c] + Hesperetin_3_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_3_Glc |
Hesperetin_3_Glc |
UidP |
Transport of D-Glucuronate Hesperetin 3-O-Glucuronide (Aglycone Of Hesperidin) |
Hesperetin_3_glc[e] -> Hesperetin_3_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_3_Glc |
Hesperetin_3_Glc |
UidB |
Glucuronate transport in via proton symport Hesperetin 3-O-Glucuronide (Aglycone Of Hesperidin) |
Hesperetin_3_glc[e] + h[e] -> Hesperetin_3_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_3_Glc |
Hesperetin_3_Glc |
UidB |
Glucuronate transport in via proton symport Hesperetin 3-O-Glucuronide (Aglycone Of Hesperidin), periplasmatic |
h[p] + Hesperetin_3_glc[p] -> h[c] + Hesperetin_3_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_3_Glc |
Hesperetin_3_Glc |
n.a. |
beta-glucuronidase reaction product export Hesperetin 3-O-Glucuronide (Aglycone Of Hesperidin) |
Hesperetin_3_glc[c] -> Hesperetin_3_glc[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_3_Glc |
Hesperetin_3_Glc |
n.a. |
beta-glucuronidase reaction product export Hesperetin 3-O-Glucuronide (Aglycone Of Hesperidin), periplasmatic |
Hesperetin_3_glc[c] -> Hesperetin_3_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_3_Glc |
Hesperetin_3_Glc |
n.a. |
Hesperetin 3-O-Glucuronide (Aglycone Of Hesperidin) diffusion extracellular to periplasm |
Hesperetin_3_glc[e] <=> Hesperetin_3_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_3_S |
Hesperetin_3_S |
n.a. |
beta-glucuronidase reaction product export Hesperetin 3-O-Sulfate |
Hesperetin_3_s[c] -> Hesperetin_3_s[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_3_S |
Hesperetin_3_S |
n.a. |
beta-glucuronidase reaction product export Hesperetin 3-O-Sulfate, periplasmatic |
Hesperetin_3_s[c] -> Hesperetin_3_s[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_3_S |
Hesperetin_3_S |
n.a. |
Hesperetin 3-O-Sulfate diffusion extracellular to periplasm |
Hesperetin_3_s[e] <=> Hesperetin_3_s[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_37_Diglc |
Hesperetin_7_Glc |
UidAc |
Hesperetin 3 7-Diglucuronide beta-glucuronidase |
Hesperetin_37_diglc[c] + h2o[c] -> Hesperetin_7_glc[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_37_Diglc |
Hesperetin_3_Glc |
UidAc |
Hesperetin 3 7-Diglucuronide beta-glucuronidase |
Hesperetin_37_diglc[c] + h2o[c] -> Hesperetin_3_glc[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_37_Diglc |
Hesperetin_7_Glc |
UidAe |
Hesperetin 3 7-Diglucuronide beta-glucuronidase extracellular |
Hesperetin_37_diglc[e] + h2o[e] -> Hesperetin_7_glc[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_37_Diglc |
Hesperetin_3_Glc |
UidAe |
Hesperetin 3 7-Diglucuronide beta-glucuronidase extracellular |
Hesperetin_37_diglc[e] + h2o[e] -> Hesperetin_3_glc[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_37_Diglc |
Hesperetin_3_Glc |
UidAe |
Hesperetin 3 7-Diglucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Hesperetin_37_diglc[p] -> glcur[p] + Hesperetin_3_glc[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_37_Diglc |
Hesperetin_7_Glc |
n.a. |
Hesperetin 3 7-Diglucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Hesperetin_37_diglc[p] -> glcur[p] + Hesperetin_7_glc[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_37_Diglc |
Hesperetin_37_Diglc |
UidABC |
Predicted glucuronide ABC transporter Hesperetin 3,7-Diglucuronide |
atp[c] + Hesperetin_37_diglc[e] + h2o[c] -> adp[c] + Hesperetin_37_diglc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_37_Diglc |
Hesperetin_37_Diglc |
UidP |
Transport of D-Glucuronate Hesperetin 3 7-Diglucuronide |
Hesperetin_37_diglc[e] -> Hesperetin_37_diglc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_37_Diglc |
Hesperetin_37_Diglc |
UidB |
Glucuronate transport in via proton symport Hesperetin 3 7-Diglucuronide |
Hesperetin_37_diglc[e] + h[e] -> Hesperetin_37_diglc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_37_Diglc |
Hesperetin_37_Diglc |
UidB |
Glucuronate transport in via proton symport Hesperetin 3 7-Diglucuronide, periplasmatic |
h[p] + Hesperetin_37_diglc[p] -> h[c] + Hesperetin_37_diglc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_37_Diglc |
Hesperetin_37_Diglc |
n.a. |
Hesperetin 3,7-Diglucuronide diffusion extracellular to periplasm |
Hesperetin_37_diglc[e] <=> Hesperetin_37_diglc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_3Glc_7S |
Hesperetin_7_S |
UidAc |
Hesperetin 3-O-Glucuronide 7-Sulfate beta-glucuronidase |
Hesperetin_3glc_7s[c] + h2o[c] -> Hesperetin_7_s[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_3Glc_7S |
Hesperetin_7_S |
UidAe |
Hesperetin 3-O-Glucuronide 7-Sulfate beta-glucuronidase extracellular |
Hesperetin_3glc_7s[e] + h2o[e] -> Hesperetin_7_s[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_3Glc_7S |
Hesperetin_7_S |
UidAe |
Hesperetin 3-O-Glucuronide 7-Sulfate beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Hesperetin_3glc_7s[p] -> glcur[p] + h[p] + Hesperetin_7_s[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_3Glc_7S |
Hesperetin_3Glc_7S |
UidABC |
Predicted glucuronide ABC transporter Hesperetin 3-O-Glucuronide 7-Sulfate |
atp[c] + Hesperetin_3glc_7s[e] + h2o[c] -> adp[c] + Hesperetin_3glc_7s[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_3Glc_7S |
Hesperetin_3Glc_7S |
UidP |
Transport of D-Glucuronate Hesperetin 3-O-Glucuronide 7-Sulfate |
Hesperetin_3glc_7s[e] -> Hesperetin_3glc_7s[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_3Glc_7S |
Hesperetin_3Glc_7S |
UidB |
Glucuronate transport in via proton symport Hesperetin 3-O-Glucuronide 7-Sulfate |
Hesperetin_3glc_7s[e] + h[e] -> Hesperetin_3glc_7s[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_3Glc_7S |
Hesperetin_3Glc_7S |
UidB |
Glucuronate transport in via proton symport Hesperetin 3-O-Glucuronide 7-Sulfate, periplasmatic |
h[p] + Hesperetin_3glc_7s[p] -> h[c] + Hesperetin_3glc_7s[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_3Glc_7S |
Hesperetin_3Glc_7S |
n.a. |
Hesperetin 3-O-Glucuronide 7-Sulfate diffusion extracellular to periplasm |
Hesperetin_3glc_7s[e] <=> Hesperetin_3glc_7s[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_7_Glc |
Hesperetin |
UidAc |
Hesperetin 7-O-Glucuronide (Aglycone Of Hesperidin) beta-glucuronidase |
Hesperetin_7_glc[c] + h2o[c] -> Hesperetin[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_7_Glc |
Hesperetin |
UidAe |
Hesperetin 7-O-Glucuronide (Aglycone Of Hesperidin) beta-glucuronidase extracellular |
Hesperetin_7_glc[e] + h2o[e] -> Hesperetin[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_7_Glc |
Hesperetin |
UidAe |
Hesperetin 7-O-Glucuronide (Aglycone Of Hesperidin) beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Hesperetin_7_glc[p] -> glcur[p] + Hesperetin[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_7_Glc |
Hesperetin_7_Glc |
UidABC |
Predicted glucuronide ABC transporter Hesperetin 7-O-Glucuronide (Aglycone Of Hesperidin) |
atp[c] + Hesperetin_7_glc[e] + h2o[c] -> adp[c] + Hesperetin_7_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_7_Glc |
Hesperetin_7_Glc |
UidP |
Transport of D-Glucuronate Hesperetin 7-O-Glucuronide (Aglycone Of Hesperidin) |
Hesperetin_7_glc[e] -> Hesperetin_7_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_7_Glc |
Hesperetin_7_Glc |
UidB |
Glucuronate transport in via proton symport Hesperetin 7-O-Glucuronide (Aglycone Of Hesperidin) |
Hesperetin_7_glc[e] + h[e] -> Hesperetin_7_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_7_Glc |
Hesperetin_7_Glc |
UidB |
Glucuronate transport in via proton symport Hesperetin 7-O-Glucuronide (Aglycone Of Hesperidin), periplasmatic |
h[p] + Hesperetin_7_glc[p] -> h[c] + Hesperetin_7_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_7_Glc |
Hesperetin_7_Glc |
n.a. |
beta-glucuronidase reaction product export Hesperetin 7-O-Glucuronide (Aglycone Of Hesperidin) |
Hesperetin_7_glc[c] -> Hesperetin_7_glc[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_7_Glc |
Hesperetin_7_Glc |
n.a. |
beta-glucuronidase reaction product export Hesperetin 7-O-Glucuronide (Aglycone Of Hesperidin), periplasmatic |
Hesperetin_7_glc[c] -> Hesperetin_7_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_7_Glc |
Hesperetin_7_Glc |
n.a. |
Hesperetin 7-O-Glucuronide (Aglycone Of Hesperidin) diffusion extracellular to periplasm |
Hesperetin_7_glc[e] <=> Hesperetin_7_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_7_S |
Hesperetin_7_S |
n.a. |
beta-glucuronidase reaction product export Hesperetin 7-O-Sulfate |
Hesperetin_7_s[c] -> Hesperetin_7_s[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_7_S |
Hesperetin_7_S |
n.a. |
beta-glucuronidase reaction product export Hesperetin 7-O-Sulfate, periplasmatic |
Hesperetin_7_s[c] -> Hesperetin_7_s[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_7_S |
Hesperetin_7_S |
n.a. |
Hesperetin 7-O-Sulfate diffusion extracellular to periplasm |
Hesperetin_7_s[e] <=> Hesperetin_7_s[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_7Glc_3S |
Hesperetin_3_S |
UidAc |
Hesperetin 7-O-Glucuronide 3-Sulfate beta-glucuronidase |
Hesperetin_7glc_3s[c] + h2o[c] -> Hesperetin_3_s[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_7Glc_3S |
Hesperetin_3_S |
UidAe |
Hesperetin 7-O-Glucuronide 3-Sulfate beta-glucuronidase extracellular |
Hesperetin_7glc_3s[e] + h2o[e] -> Hesperetin_3_s[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_7Glc_3S |
Hesperetin_3_S |
UidAe |
Hesperetin 7-O-Glucuronide 3-Sulfate beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Hesperetin_7glc_3s[p] -> glcur[p] + h[p] + Hesperetin_3_s[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_7Glc_3S |
Hesperetin_7Glc_3S |
UidABC |
Predicted glucuronide ABC transporter Hesperetin 7-O-Glucuronide 3-Sulfate |
atp[c] + Hesperetin_7glc_3s[e] + h2o[c] -> adp[c] + Hesperetin_7glc_3s[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_7Glc_3S |
Hesperetin_7Glc_3S |
UidP |
Transport of D-Glucuronate Hesperetin 7-O-Glucuronide 3-Sulfate |
Hesperetin_7glc_3s[e] -> Hesperetin_7glc_3s[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_7Glc_3S |
Hesperetin_7Glc_3S |
UidB |
Glucuronate transport in via proton symport Hesperetin 7-O-Glucuronide 3-Sulfate |
Hesperetin_7glc_3s[e] + h[e] -> Hesperetin_7glc_3s[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_7Glc_3S |
Hesperetin_7Glc_3S |
UidB |
Glucuronate transport in via proton symport Hesperetin 7-O-Glucuronide 3-Sulfate, periplasmatic |
h[p] + Hesperetin_7glc_3s[p] -> h[c] + Hesperetin_7glc_3s[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin_7Glc_3S |
Hesperetin_7Glc_3S |
n.a. |
Hesperetin 7-O-Glucuronide 3-Sulfate diffusion extracellular to periplasm |
Hesperetin_7glc_3s[e] <=> Hesperetin_7glc_3s[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin |
Hesperetin |
n.a. |
beta-glucuronidase reaction product export Hesperetin |
Hesperetin[c] -> Hesperetin[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin |
Hesperetin |
n.a. |
beta-glucuronidase reaction product export Hesperetin, periplasmatic |
Hesperetin[c] -> Hesperetin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01094 |
Hesperetin |
Hesperetin |
n.a. |
Hesperetin diffusion extracellular to periplasm |
Hesperetin[e] <=> Hesperetin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
Ibuprofen-S |
Ibuprofen-S |
n.a. |
beta-glucuronidase reaction product export ibuprofen-S |
ibuprofen-S[c] -> ibuprofen-S[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
Ibuprofen-S |
Ibuprofen-S |
n.a. |
beta-glucuronidase reaction product export ibuprofen-S, periplasmatic |
ibuprofen-S[c] -> ibuprofen-S[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
Ibuprofen-S |
Ibuprofen-S |
n.a. |
ibuprofen-S diffusion extracellular to periplasm |
ibuprofen-S[e] <=> ibuprofen-S[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
Ibuprofen Acyl Glucuronide |
Ibuprofen-S |
UidAc |
ibuprofen acyl glucuronide beta-glucuronidase |
ibuprofen acyl glucuronide[c] + h2o[c] -> ibuprofen-S[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01050 |
Ibuprofen Acyl Glucuronide |
Ibuprofen-S |
UidAe |
ibuprofen acyl glucuronide beta-glucuronidase extracellular |
ibuprofen acyl glucuronide[e] + h2o[e] -> ibuprofen-S[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01050 |
Ibuprofen Acyl Glucuronide |
Ibuprofen-S |
UidAe |
ibuprofen acyl glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + ibuprofen acyl glucuronide[p] -> glcur[p] + h[p] + ibuprofen-S[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01050 |
Ibuprofen Acyl Glucuronide |
Ibuprofen Acyl Glucuronide |
UidABC |
Predicted glucuronide ABC transporter ibuprofen acyl glucuronide |
atp[c] + ibuprofen acyl glucuronide[e] + h2o[c] -> adp[c] + ibuprofen acyl glucuronide[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
Ibuprofen Acyl Glucuronide |
Ibuprofen Acyl Glucuronide |
UidP |
Transport of D-Glucuronate ibuprofen acyl glucuronide |
ibuprofen acyl glucuronide[e] -> ibuprofen acyl glucuronide[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
Ibuprofen Acyl Glucuronide |
Ibuprofen Acyl Glucuronide |
UidB |
Glucuronate transport in via proton symport ibuprofen acyl glucuronide |
ibuprofen acyl glucuronide[e] + h[e] -> ibuprofen acyl glucuronide[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
Ibuprofen Acyl Glucuronide |
Ibuprofen Acyl Glucuronide |
UidB |
Glucuronate transport in via proton symport ibuprofen acyl glucuronide, periplasmatic |
h[p] + ibuprofen acyl glucuronide[p] -> h[c] + ibuprofen acyl glucuronide[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01050 |
Ibuprofen Acyl Glucuronide |
Ibuprofen Acyl Glucuronide |
n.a. |
ibuprofen acyl glucuronide diffusion extracellular to periplasm |
ibuprofen acyl glucuronide[e] <=> ibuprofen acyl glucuronide[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00328 |
Indomethacin_Glc |
Indomethacin |
UidAc |
Indomethacin Glucuronide beta-glucuronidase |
Indomethacin_glc[c] + h2o[c] -> Indomethacin[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 23829165 |
| DB00328 |
Indomethacin_Glc |
Indomethacin |
UidAe |
Indomethacin Glucuronide beta-glucuronidase extracellular |
Indomethacin_glc[e] + h2o[e] -> Indomethacin[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 23829165 |
| DB00328 |
Indomethacin_Glc |
Indomethacin |
UidAe |
Indomethacin Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Indomethacin_glc[p] -> glcur[p] + h[p] + Indomethacin[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00328 |
Indomethacin_Glc |
Indomethacin_Glc |
UidABC |
Predicted glucuronide ABC transporter Indomethacin Glucuronide |
atp[c] + Indomethacin_glc[e] + h2o[c] -> adp[c] + Indomethacin_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00328 |
Indomethacin_Glc |
Indomethacin_Glc |
UidP |
Transport of D-Glucuronate Indomethacin Glucuronide |
Indomethacin_glc[e] -> Indomethacin_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00328 |
Indomethacin_Glc |
Indomethacin_Glc |
UidB |
Glucuronate transport in via proton symport Indomethacin Glucuronide |
Indomethacin_glc[e] + h[e] -> Indomethacin_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00328 |
Indomethacin_Glc |
Indomethacin_Glc |
UidB |
Glucuronate transport in via proton symport Indomethacin Glucuronide, periplasmatic |
h[p] + Indomethacin_glc[p] -> h[c] + Indomethacin_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00328 |
Indomethacin_Glc |
Indomethacin_Glc |
n.a. |
Indomethacin Glucuronide diffusion extracellular to periplasm |
Indomethacin_glc[e] <=> Indomethacin_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00328 |
Indomethacin |
Indomethacin |
n.a. |
beta-glucuronidase reaction product export Indomethacin |
Indomethacin[c] -> Indomethacin[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00328 |
Indomethacin |
Indomethacin |
n.a. |
beta-glucuronidase reaction product export Indomethacin, periplasmatic |
Indomethacin[c] -> Indomethacin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00328 |
Indomethacin |
Indomethacin |
n.a. |
Indomethacin diffusion extracellular to periplasm |
Indomethacin[e] <=> Indomethacin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00224 |
Indinavir_M1 |
Indinavir |
UidAc |
Indanyl Glucuronide M1 beta-glucuronidase |
Indinavir_m1[c] + h2o[c] -> Indinavir[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00224 |
Indinavir_M1 |
Indinavir |
UidAe |
Indanyl Glucuronide M1 beta-glucuronidase extracellular |
Indinavir_m1[e] + h2o[e] -> Indinavir[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00224 |
Indinavir_M1 |
Indinavir_M1 |
UidABC |
Predicted glucuronide ABC transporter Indanyl Glucuronide M1 |
atp[c] + Indinavir_m1[e] + h2o[c] -> adp[c] + Indinavir_m1[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00224 |
Indinavir_M1 |
Indinavir_M1 |
UidP |
Transport of D-Glucuronate Indanyl Glucuronide M1 |
Indinavir_m1[e] -> Indinavir_m1[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00224 |
Indinavir_M1 |
Indinavir_M1 |
UidB |
Glucuronate transport in via proton symport Indanyl Glucuronide M1 |
Indinavir_m1[e] + h[e] -> Indinavir_m1[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00224 |
Indinavir_M1 |
Indinavir_M1 |
UidB |
Glucuronate transport in via proton symport Indanyl Glucuronide M1, periplasmatic |
h[p] + Indinavir_m1[p] -> h[c] + Indinavir_m1[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00224 |
Indinavir_M1 |
Indinavir_M1 |
n.a. |
Indanyl Glucuronide M1 diffusion extracellular to periplasm |
Indinavir_m1[e] <=> Indinavir_m1[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00224 |
Indinavir |
Indinavir |
n.a. |
beta-glucuronidase reaction product export Indinavir |
Indinavir[c] -> Indinavir[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00224 |
Indinavir |
Indinavir |
n.a. |
beta-glucuronidase reaction product export Indinavir, periplasmatic |
Indinavir[c] -> Indinavir[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00224 |
Indinavir |
Indinavir |
n.a. |
Indinavir diffusion extracellular to periplasm |
Indinavir[e] <=> Indinavir[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00951 |
Isoniazid |
Isoniazid |
NatABC |
Isoniazid ABC transporter |
atp[c] + Isoniazid[e] + h2o[c] -> adp[c] + Isoniazid[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00951 |
Isoniazid |
Isoniazid |
NatABC |
Isoniazid ABC transporter, periplasmatic |
atp[c] + h2o[c] + Isoniazid[p] -> adp[c] + h[c] + Isoniazid[c] + pi[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00951 |
Isoniazid |
N-Acetylisoniazid |
NAT |
5-aminosalicylic acid acetylation |
Isoniazid[c] + accoa[c] <=> N-Acetylisoniazid[c] + coa[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 11344150, PMID: 15447630 |
| DB00951 |
Isoniazid |
N-Acetylisoniazid |
eNAT |
5-aminosalicylic acid acetylation |
Isoniazid[e] + accoa[e] <=> N-Acetylisoniazid[e] + coa[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 11344150, PMID: 15447630 |
| DB00951 |
Isoniazid |
Isoniazid |
n.a. |
Isoniazid permease, periplasmatic |
Isoniazid[p] <=> Isoniazid[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00951 |
Isoniazid |
Isoniazid |
n.a. |
Isoniazid diffusion extracellular to periplasm |
Isoniazid[e] <=> Isoniazid[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB09401 |
Isosorbide 5-Mononitrate _Glc |
Isosorbide 5-Mononitrate |
UidAc |
Isosorbide 5-Mononitrate 2-Beta-D-Glucuronide beta-glucuronidase |
Isosorbide 5-Mononitrate _glc[c] + h2o[c] -> Isosorbide 5-Mononitrate [c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB09401 |
Isosorbide 5-Mononitrate _Glc |
Isosorbide 5-Mononitrate |
UidAe |
Isosorbide 5-Mononitrate 2-Beta-D-Glucuronide beta-glucuronidase extracellular |
Isosorbide 5-Mononitrate _glc[e] + h2o[e] -> Isosorbide 5-Mononitrate [e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB09401 |
Isosorbide 5-Mononitrate _Glc |
Isosorbide 5-Mononitrate |
UidAe |
Isosorbide 5-Mononitrate 2-Beta-D-Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Isosorbide 5-Mononitrate _glc[p] -> glcur[p] + Isosorbide 5-Mononitrate [p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB09401 |
Isosorbide 5-Mononitrate _Glc |
Isosorbide 5-Mononitrate _Glc |
UidABC |
Predicted glucuronide ABC transporter Isosorbide 5-Mononitrate 2-Beta-D-Glucuronide |
atp[c] + Isosorbide 5-Mononitrate _glc[e] + h2o[c] -> adp[c] + Isosorbide 5-Mononitrate _glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB09401 |
Isosorbide 5-Mononitrate _Glc |
Isosorbide 5-Mononitrate _Glc |
UidP |
Transport of D-Glucuronate Isosorbide 5-Mononitrate 2-Beta-D-Glucuronide |
Isosorbide 5-Mononitrate _glc[e] -> Isosorbide 5-Mononitrate _glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB09401 |
Isosorbide 5-Mononitrate _Glc |
Isosorbide 5-Mononitrate _Glc |
UidB |
Glucuronate transport in via proton symport Isosorbide 5-Mononitrate 2-Beta-D-Glucuronide |
Isosorbide 5-Mononitrate _glc[e] + h[e] -> Isosorbide 5-Mononitrate _glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB09401 |
Isosorbide 5-Mononitrate _Glc |
Isosorbide 5-Mononitrate _Glc |
UidB |
Glucuronate transport in via proton symport Isosorbide 5-Mononitrate 2-Beta-D-Glucuronide, periplasmatic |
h[p] + Isosorbide 5-Mononitrate _glc[p] -> h[c] + Isosorbide 5-Mononitrate _glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB09401 |
Isosorbide 5-Mononitrate _Glc |
Isosorbide 5-Mononitrate _Glc |
n.a. |
Isosorbide 5-Mononitrate 2-Beta-D-Glucuronide diffusion extracellular to periplasm |
Isosorbide 5-Mononitrate _glc[e] <=> Isosorbide 5-Mononitrate _glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB09401 |
Isosorbide 5-Mononitrate |
Isosorbide 5-Mononitrate |
n.a. |
beta-glucuronidase reaction product export Isosorbide 5-Mononitrate |
Isosorbide 5-Mononitrate [c] -> Isosorbide 5-Mononitrate [e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB09401 |
Isosorbide 5-Mononitrate |
Isosorbide 5-Mononitrate |
n.a. |
beta-glucuronidase reaction product export Isosorbide 5-Mononitrate, periplasmatic |
Isosorbide 5-Mononitrate [c] -> Isosorbide 5-Mononitrate [p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB09401 |
Isosorbide 5-Mononitrate |
Isosorbide 5-Mononitrate |
n.a. |
Isosorbide 5-Mononitrate diffusion extracellular to periplasm |
Isosorbide 5-Mononitrate [e] <=> Isosorbide 5-Mononitrate [p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01009 |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)_Glc |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid) |
UidAc |
Ketoprofen Glucuronide beta-glucuronidase |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)_glc[c] + h2o[c] -> Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 23829165 |
| DB01009 |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)_Glc |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid) |
UidAe |
Ketoprofen Glucuronide beta-glucuronidase extracellular |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)_glc[e] + h2o[e] -> Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 23829165 |
| DB01009 |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)_Glc |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid) |
UidAe |
Ketoprofen Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)_glc[p] -> glcur[p] + h[p] + Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01009 |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)_Glc |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)_Glc |
UidABC |
Predicted glucuronide ABC transporter Ketoprofen Glucuronide |
atp[c] + Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)_glc[e] + h2o[c] -> adp[c] + Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01009 |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)_Glc |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)_Glc |
UidP |
Transport of D-Glucuronate Ketoprofen Glucuronide |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)_glc[e] -> Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01009 |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)_Glc |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)_Glc |
UidB |
Glucuronate transport in via proton symport Ketoprofen Glucuronide |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)_glc[e] + h[e] -> Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01009 |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)_Glc |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)_Glc |
UidB |
Glucuronate transport in via proton symport Ketoprofen Glucuronide, periplasmatic |
h[p] + Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)_glc[p] -> h[c] + Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01009 |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)_Glc |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)_Glc |
n.a. |
Ketoprofen Glucuronide diffusion extracellular to periplasm |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)_glc[e] <=> Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01009 |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid) |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid) |
n.a. |
beta-glucuronidase reaction product export Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid) |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)[c] -> Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01009 |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid) |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid) |
n.a. |
beta-glucuronidase reaction product export Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid), periplasmatic |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)[c] -> Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01009 |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid) |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid) |
n.a. |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid) diffusion extracellular to periplasm |
Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)[e] <=> Ketoprofen (2-(3-Benzoylphenyl)Propionic Acid)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00581 |
Lactulose |
Lactulose |
LacY |
Lactulose transport via proton symport |
h[e] + Lactulose[e] <=> h[c] + Lactulose[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartan-E3174/ Losartan-M6 |
Losartan-E3174/ Losartan-M6 |
n.a. |
beta-glucuronidase reaction product export Losartan-E3174/ losartan-M6 |
Losartan-E3174/ losartan-M6[c] -> Losartan-E3174/ losartan-M6[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartan-E3174/ Losartan-M6 |
Losartan-E3174/ Losartan-M6 |
n.a. |
beta-glucuronidase reaction product export Losartan-E3174/ losartan-M6, periplasmatic |
Losartan-E3174/ losartan-M6[c] -> Losartan-E3174/ losartan-M6[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartan-E3174/ Losartan-M6 |
Losartan-E3174/ Losartan-M6 |
n.a. |
Losartan-E3174/ losartan-M6 diffusion extracellular to periplasm |
Losartan-E3174/ losartan-M6[e] <=> Losartan-E3174/ losartan-M6[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartan1Gluc |
Losartan |
UidAc |
Losartan-N1-glucuronide beta-glucuronidase |
Losartan1gluc[c] + h2o[c] -> Losartan[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartan1Gluc |
Losartan |
UidAe |
Losartan-N1-glucuronide beta-glucuronidase extracellular |
Losartan1gluc[e] + h2o[e] -> Losartan[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartan1Gluc |
Losartan |
UidAe |
Losartan-N1-glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Losartan1gluc[p] -> glcur[p] + h[p] + Losartan[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartan1Gluc |
Losartan1Gluc |
UidABC |
Predicted glucuronide ABC transporter Losartan-N1-glucuronide |
atp[c] + Losartan1gluc[e] + h2o[c] -> adp[c] + Losartan1gluc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartan1Gluc |
Losartan1Gluc |
UidP |
Transport of D-Glucuronate Losartan-N1-glucuronide |
Losartan1gluc[e] -> Losartan1gluc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartan1Gluc |
Losartan1Gluc |
UidB |
Glucuronate transport in via proton symport Losartan-N1-glucuronide |
Losartan1gluc[e] + h[e] -> Losartan1gluc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartan1Gluc |
Losartan1Gluc |
UidB |
Glucuronate transport in via proton symport Losartan-N1-glucuronide, periplasmatic |
h[p] + Losartan1gluc[p] -> h[c] + Losartan1gluc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartan1Gluc |
Losartan1Gluc |
n.a. |
Losartan-N1-glucuronide diffusion extracellular to periplasm |
Losartan1gluc[e] <=> Losartan1gluc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartanm4 |
Losartan-E3174/ Losartan-M6 |
UidAc |
Losartan-M4 (glucuronide derivative) beta-glucuronidase |
Losartanm4[c] + h2o[c] -> Losartan-E3174/ losartan-M6[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartanm4 |
Losartan-E3174/ Losartan-M6 |
UidAe |
Losartan-M4 (glucuronide derivative) beta-glucuronidase extracellular |
Losartanm4[e] + h2o[e] -> Losartan-E3174/ losartan-M6[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartanm4 |
Losartan-E3174/ Losartan-M6 |
UidAe |
Losartan-M4 (glucuronide derivative) beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Losartanm4[p] -> glcur[p] + h[p] + Losartan-E3174/ losartan-M6[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartanm4 |
Losartanm4 |
UidABC |
Predicted glucuronide ABC transporter Losartan-M4 (glucuronide derivative) |
atp[c] + Losartanm4[e] + h2o[c] -> adp[c] + Losartanm4[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartanm4 |
Losartanm4 |
UidP |
Transport of D-Glucuronate Losartan-M4 (glucuronide derivative) |
Losartanm4[e] -> Losartanm4[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartanm4 |
Losartanm4 |
UidB |
Glucuronate transport in via proton symport Losartan-M4 (glucuronide derivative) |
Losartanm4[e] + h[e] -> Losartanm4[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartanm4 |
Losartanm4 |
UidB |
Glucuronate transport in via proton symport Losartan-M4 (glucuronide derivative), periplasmatic |
h[p] + Losartanm4[p] -> h[c] + Losartanm4[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartanm4 |
Losartanm4 |
n.a. |
Losartan-M4 (glucuronide derivative) diffusion extracellular to periplasm |
Losartanm4[e] <=> Losartanm4[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartanm7 |
Losartan |
UidAc |
Losartan-N2-glucuronide / Losartan-M7 beta-glucuronidase |
Losartanm7[c] + h2o[c] -> Losartan[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartanm7 |
Losartan |
UidAe |
Losartan-N2-glucuronide / Losartan-M7 beta-glucuronidase extracellular |
Losartanm7[e] + h2o[e] -> Losartan[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartanm7 |
Losartan |
UidAe |
Losartan-N2-glucuronide / Losartan-M7 beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Losartanm7[p] -> glcur[p] + h[p] + Losartan[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartanm7 |
Losartanm7 |
UidABC |
Predicted glucuronide ABC transporter Losartan-N2-glucuronide / Losartan-M7 |
atp[c] + Losartanm7[e] + h2o[c] -> adp[c] + Losartanm7[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartanm7 |
Losartanm7 |
UidP |
Transport of D-Glucuronate Losartan-N2-glucuronide / Losartan-M7 |
Losartanm7[e] -> Losartanm7[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartanm7 |
Losartanm7 |
UidB |
Glucuronate transport in via proton symport Losartan-N2-glucuronide / Losartan-M7 |
Losartanm7[e] + h[e] -> Losartanm7[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartanm7 |
Losartanm7 |
UidB |
Glucuronate transport in via proton symport Losartan-N2-glucuronide / Losartan-M7, periplasmatic |
h[p] + Losartanm7[p] -> h[c] + Losartanm7[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartanm7 |
Losartanm7 |
n.a. |
Losartan-N2-glucuronide / Losartan-M7 diffusion extracellular to periplasm |
Losartanm7[e] <=> Losartanm7[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartan |
Losartan |
n.a. |
beta-glucuronidase reaction product export Losartan |
Losartan[c] -> Losartan[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartan |
Losartan |
n.a. |
beta-glucuronidase reaction product export Losartan, periplasmatic |
Losartan[c] -> Losartan[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00678 |
Losartan |
Losartan |
n.a. |
Losartan diffusion extracellular to periplasm |
Losartan[e] <=> Losartan[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
Midazolam_Glc |
Midazolam |
UidAc |
Midazolam Glucuronide beta-glucuronidase |
Midazolam_glc[c] + h2o[c] -> Midazolam[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00683 |
Midazolam_Glc |
Midazolam |
UidAe |
Midazolam Glucuronide beta-glucuronidase extracellular |
Midazolam_glc[e] + h2o[e] -> Midazolam[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00683 |
Midazolam_Glc |
Midazolam |
UidAe |
Midazolam Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Midazolam_glc[p] -> glcur[p] + Midazolam[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00683 |
Midazolam_Glc |
Midazolam_Glc |
UidABC |
Predicted glucuronide ABC transporter Midazolam Glucuronide |
atp[c] + Midazolam_glc[e] + h2o[c] -> adp[c] + Midazolam_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
Midazolam_Glc |
Midazolam_Glc |
UidP |
Transport of D-Glucuronate Midazolam Glucuronide |
Midazolam_glc[e] -> Midazolam_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
Midazolam_Glc |
Midazolam_Glc |
UidB |
Glucuronate transport in via proton symport Midazolam Glucuronide |
Midazolam_glc[e] + h[e] -> Midazolam_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
Midazolam_Glc |
Midazolam_Glc |
UidB |
Glucuronate transport in via proton symport Midazolam Glucuronide, periplasmatic |
h[p] + Midazolam_glc[p] -> h[c] + Midazolam_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
Midazolam_Glc |
Midazolam_Glc |
n.a. |
Midazolam Glucuronide diffusion extracellular to periplasm |
Midazolam_glc[e] <=> Midazolam_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
Midazolamglc |
Midazolam |
UidAc |
Midazolam-glucuronide beta-glucuronidase |
Midazolamglc[c] + h2o[c] -> Midazolam[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00683 |
Midazolamglc |
Midazolam |
UidAe |
Midazolam-glucuronide beta-glucuronidase extracellular |
Midazolamglc[e] + h2o[e] -> Midazolam[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00683 |
Midazolamglc |
Midazolam |
UidAe |
Midazolam-glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Midazolamglc[p] -> glcur[p] + Midazolam[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00683 |
Midazolamglc |
Midazolamglc |
UidABC |
Predicted glucuronide ABC transporter Midazolam-glucuronide |
atp[c] + Midazolamglc[e] + h2o[c] -> adp[c] + Midazolamglc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
Midazolamglc |
Midazolamglc |
UidP |
Transport of D-Glucuronate Midazolam-glucuronide |
Midazolamglc[e] -> Midazolamglc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
Midazolamglc |
Midazolamglc |
UidB |
Glucuronate transport in via proton symport Midazolam-glucuronide |
Midazolamglc[e] + h[e] -> Midazolamglc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
Midazolamglc |
Midazolamglc |
UidB |
Glucuronate transport in via proton symport Midazolam-glucuronide, periplasmatic |
h[p] + Midazolamglc[p] -> h[c] + Midazolamglc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
Midazolamglc |
Midazolamglc |
n.a. |
Midazolam-Glucuronide diffusion extracellular to periplasm |
Midazolamglc[e] <=> Midazolamglc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
Midazolam |
Midazolam |
n.a. |
beta-glucuronidase reaction product export Midazolam |
Midazolam[c] -> Midazolam[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
Midazolam |
Midazolam |
n.a. |
beta-glucuronidase reaction product export Midazolam, periplasmatic |
Midazolam[c] -> Midazolam[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00683 |
Midazolam |
Midazolam |
n.a. |
Midazolam diffusion extracellular to periplasm |
Midazolam[e] <=> Midazolam[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB11716 |
Misonidazole_Glc |
Misonidazole |
UidAc |
Misonidazole Glucuronide beta-glucuronidase |
Misonidazole_glc[c] + h2o[c] -> Misonidazole[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB11716 |
Misonidazole_Glc |
Misonidazole |
UidAe |
Misonidazole Glucuronide beta-glucuronidase extracellular |
Misonidazole_glc[e] + h2o[e] -> Misonidazole[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB11716 |
Misonidazole_Glc |
Misonidazole |
UidAe |
Misonidazole Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Misonidazole_glc[p] -> glcur[p] + Misonidazole[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB11716 |
Misonidazole_Glc |
Misonidazole_Glc |
UidABC |
Predicted glucuronide ABC transporter Misonidazole Glucuronide |
atp[c] + Misonidazole_glc[e] + h2o[c] -> adp[c] + Misonidazole_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB11716 |
Misonidazole_Glc |
Misonidazole_Glc |
UidP |
Transport of D-Glucuronate Misonidazole Glucuronide |
Misonidazole_glc[e] -> Misonidazole_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB11716 |
Misonidazole_Glc |
Misonidazole_Glc |
UidB |
Glucuronate transport in via proton symport Misonidazole Glucuronide |
Misonidazole_glc[e] + h[e] -> Misonidazole_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB11716 |
Misonidazole_Glc |
Misonidazole_Glc |
UidB |
Glucuronate transport in via proton symport Misonidazole Glucuronide, periplasmatic |
h[p] + Misonidazole_glc[p] -> h[c] + Misonidazole_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB11716 |
Misonidazole_Glc |
Misonidazole_Glc |
n.a. |
Misonidazole Glucuronide diffusion extracellular to periplasm |
Misonidazole_glc[e] <=> Misonidazole_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB11716 |
Misonidazole |
Misonidazole |
n.a. |
beta-glucuronidase reaction product export Misonidazole |
Misonidazole[c] -> Misonidazole[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB11716 |
Misonidazole |
Misonidazole |
n.a. |
beta-glucuronidase reaction product export Misonidazole, periplasmatic |
Misonidazole[c] -> Misonidazole[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB11716 |
Misonidazole |
Misonidazole |
n.a. |
Misonidazole diffusion extracellular to periplasm |
Misonidazole[e] <=> Misonidazole[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00295 |
Morphine_3Glc |
Morphine |
UidAc |
Morphine 3-Glucuronide beta-glucuronidase |
Morphine_3glc[c] + h2o[c] -> Morphine[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00295 |
Morphine_3Glc |
Morphine |
UidAe |
Morphine 3-Glucuronide beta-glucuronidase extracellular |
Morphine_3glc[e] + h2o[e] -> Morphine[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00295 |
Morphine_3Glc |
Morphine |
UidAe |
Morphine 3-Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Morphine_3glc[p] -> glcur[p] + h[p] + Morphine[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00295 |
Morphine_3Glc |
Morphine_3Glc |
UidABC |
Predicted glucuronide ABC transporter Morphine 3-Glucuronide |
atp[c] + Morphine_3glc[e] + h2o[c] -> adp[c] + Morphine_3glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00295 |
Morphine_3Glc |
Morphine_3Glc |
UidP |
Transport of D-Glucuronate Morphine 3-Glucuronide |
Morphine_3glc[e] -> Morphine_3glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00295 |
Morphine_3Glc |
Morphine_3Glc |
UidB |
Glucuronate transport in via proton symport Morphine 3-Glucuronide |
Morphine_3glc[e] + h[e] -> Morphine_3glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00295 |
Morphine_3Glc |
Morphine_3Glc |
UidB |
Glucuronate transport in via proton symport Morphine 3-Glucuronide, periplasmatic |
h[p] + Morphine_3glc[p] -> h[c] + Morphine_3glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00295 |
Morphine_3Glc |
Morphine_3Glc |
n.a. |
Morphine 3-Glucuronide diffusion extracellular to periplasm |
Morphine_3glc[e] <=> Morphine_3glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00295 |
Morphine_6Glc |
Morphine |
UidAc |
Morphine 6-Glucuronide beta-glucuronidase |
Morphine_6glc[c] + h2o[c] -> Morphine[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00295 |
Morphine_6Glc |
Morphine |
UidAe |
Morphine 6-Glucuronide beta-glucuronidase extracellular |
Morphine_6glc[e] + h2o[e] -> Morphine[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00295 |
Morphine_6Glc |
Morphine |
UidAe |
Morphine 6-Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Morphine_6glc[p] -> glcur[p] + h[p] + Morphine[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00295 |
Morphine_6Glc |
Morphine_6Glc |
UidABC |
Predicted glucuronide ABC transporter Morphine 6-Glucuronide |
atp[c] + Morphine_6glc[e] + h2o[c] -> adp[c] + Morphine_6glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00295 |
Morphine_6Glc |
Morphine_6Glc |
UidP |
Transport of D-Glucuronate Morphine 6-Glucuronide |
Morphine_6glc[e] -> Morphine_6glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00295 |
Morphine_6Glc |
Morphine_6Glc |
UidB |
Glucuronate transport in via proton symport Morphine 6-Glucuronide |
Morphine_6glc[e] + h[e] -> Morphine_6glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00295 |
Morphine_6Glc |
Morphine_6Glc |
UidB |
Glucuronate transport in via proton symport Morphine 6-Glucuronide, periplasmatic |
h[p] + Morphine_6glc[p] -> h[c] + Morphine_6glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00295 |
Morphine_6Glc |
Morphine_6Glc |
n.a. |
Morphine 6-Glucuronide diffusion extracellular to periplasm |
Morphine_6glc[e] <=> Morphine_6glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00295 |
Morphine |
Morphine |
n.a. |
beta-glucuronidase reaction product export Morphine |
Morphine[c] -> Morphine[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00295 |
Morphine |
Morphine |
n.a. |
beta-glucuronidase reaction product export Morphine, periplasmatic |
Morphine[c] -> Morphine[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00295 |
Morphine |
Morphine |
n.a. |
Morphine diffusion extracellular to periplasm |
Morphine[e] <=> Morphine[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
M-Tyramine |
N.A. |
n.a. |
m-Tyramine transport in via proton symport reversible |
h[e] + mtym[e] <=> h[c] + mtym[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00916 |
Metronidazole_Glc |
Metronidazole |
UidAc |
Metronidazole Beta-D-Glucuronide beta-glucuronidase |
Metronidazole_glc[c] + h2o[c] -> Metronidazole[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00916 |
Metronidazole_Glc |
Metronidazole |
UidAe |
Metronidazole Beta-D-Glucuronide beta-glucuronidase extracellular |
Metronidazole_glc[e] + h2o[e] -> Metronidazole[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00916 |
Metronidazole_Glc |
Metronidazole |
UidAe |
Metronidazole Beta-D-Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Metronidazole_glc[p] -> glcur[p] + Metronidazole[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00916 |
Metronidazole_Glc |
Metronidazole_Glc |
UidABC |
Predicted glucuronide ABC transporter Metronidazole Beta-D-Glucuronide |
atp[c] + Metronidazole_glc[e] + h2o[c] -> adp[c] + Metronidazole_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00916 |
Metronidazole_Glc |
Metronidazole_Glc |
UidP |
Transport of D-Glucuronate Metronidazole Beta-D-Glucuronide |
Metronidazole_glc[e] -> Metronidazole_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00916 |
Metronidazole_Glc |
Metronidazole_Glc |
UidB |
Glucuronate transport in via proton symport Metronidazole Beta-D-Glucuronide |
Metronidazole_glc[e] + h[e] -> Metronidazole_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00916 |
Metronidazole_Glc |
Metronidazole_Glc |
UidB |
Glucuronate transport in via proton symport Metronidazole Beta-D-Glucuronide, periplasmatic |
h[p] + Metronidazole_glc[p] -> h[c] + Metronidazole_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00916 |
Metronidazole_Glc |
Metronidazole_Glc |
n.a. |
Metronidazole Beta-D-Glucuronide diffusion extracellular to periplasm |
Metronidazole_glc[e] <=> Metronidazole_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00916 |
Metronidazole |
Metronidazole |
n.a. |
beta-glucuronidase reaction product export Metronidazole |
Metronidazole[c] -> Metronidazole[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00916 |
Metronidazole |
Metronidazole |
n.a. |
beta-glucuronidase reaction product export Metronidazole, periplasmatic |
Metronidazole[c] -> Metronidazole[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00916 |
Metronidazole |
Metronidazole |
n.a. |
Metronidazole diffusion extracellular to periplasm |
Metronidazole[e] <=> Metronidazole[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB03783 |
N-Hydroxylated Phenacetin_Glc |
N-Hydroxylated Phenacetin |
UidAc |
N-Hydroxylated Phenacetin Glucuronide beta-glucuronidase |
N-Hydroxylated Phenacetin_glc[c] + h2o[c] -> N-Hydroxylated Phenacetin[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB03783 |
N-Hydroxylated Phenacetin_Glc |
N-Hydroxylated Phenacetin |
UidAe |
N-Hydroxylated Phenacetin Glucuronide beta-glucuronidase extracellular |
N-Hydroxylated Phenacetin_glc[e] + h2o[e] -> N-Hydroxylated Phenacetin[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB03783 |
N-Hydroxylated Phenacetin_Glc |
N-Hydroxylated Phenacetin |
UidAe |
N-Hydroxylated Phenacetin Glucuronide beta-glucuronidase extracellular, periplasmatic |
N-Hydroxylated Phenacetin_glc[p] + h2o[p] -> N-Hydroxylated Phenacetin[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB03783 |
N-Hydroxylated Phenacetin_Glc |
N-Hydroxylated Phenacetin_Glc |
UidABC |
Predicted glucuronide ABC transporter N-Hydroxylated Phenacetin Glucuronide |
atp[c] + N-Hydroxylated Phenacetin_glc[e] + h2o[c] -> adp[c] + N-Hydroxylated Phenacetin_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB03783 |
N-Hydroxylated Phenacetin_Glc |
N-Hydroxylated Phenacetin_Glc |
UidP |
Transport of D-Glucuronate N-Hydroxylated Phenacetin Glucuronide |
N-Hydroxylated Phenacetin_glc[e] -> N-Hydroxylated Phenacetin_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB03783 |
N-Hydroxylated Phenacetin_Glc |
N-Hydroxylated Phenacetin_Glc |
UidB |
Glucuronate transport in via proton symport N-Hydroxylated Phenacetin Glucuronide |
N-Hydroxylated Phenacetin_glc[e] + h[e] -> N-Hydroxylated Phenacetin_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB03783 |
N-Hydroxylated Phenacetin_Glc |
N-Hydroxylated Phenacetin_Glc |
UidB |
Glucuronate transport in via proton symport N-Hydroxylated Phenacetin Glucuronide, periplasmatic |
N-Hydroxylated Phenacetin_glc[p] + h[p] -> N-Hydroxylated Phenacetin_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB03783 |
N-Hydroxylated Phenacetin_Glc |
N-Hydroxylated Phenacetin_Glc |
n.a. |
N-Hydroxylated Phenacetin Glucuronide diffusion extracellular to periplasm |
N-Hydroxylated Phenacetin_glc[e] <=> N-Hydroxylated Phenacetin_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB03783 |
N-Hydroxylated Phenacetin |
N-Hydroxylated Phenacetin |
n.a. |
beta-glucuronidase reaction product export N-Hydroxylated Phenacetin |
N-Hydroxylated Phenacetin[c] -> N-Hydroxylated Phenacetin[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB03783 |
N-Hydroxylated Phenacetin |
N-Hydroxylated Phenacetin |
n.a. |
beta-glucuronidase reaction product export N-Hydroxylated Phenacetin, periplasmatic |
N-Hydroxylated Phenacetin[c] -> N-Hydroxylated Phenacetin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB03783 |
N-Hydroxylated Phenacetin |
N-Hydroxylated Phenacetin |
n.a. |
N-Hydroxylated Phenacetin diffusion extracellular to periplasm |
N-Hydroxylated Phenacetin[e] <=> N-Hydroxylated Phenacetin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00446 |
Nchloramphenicol |
Nchloramphenicol |
n.a. |
Nitrosochloramphenicol diffusion extracellular to periplasm |
nChloramphenicol[e] <=> nChloramphenicol[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Neoprontosilosil |
N.A. |
AzNAD |
Neoprontosil Microbiota azo-reduction (NAD) |
NeoProntosilosil[c] + 5 nadh[c] + 5 h[c] + 2 nh4[c] <=> 3 Sulfanilamide[c] + 5 nad[c] + 4 h2o[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 5173017, PMID: 26261286 |
| n.a. |
Neoprontosilosil |
N.A. |
AzNADP |
Neoprontosil Microbiota azo-reduction (NADP) |
NeoProntosilosil[c] + 5 nadph[c] + 5 h[c] + 2 nh4[c] <=> 3 Sulfanilamide[c] + 5 nadp[c] + 4 h2o[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 5173017, PMID: 26261286 |
| n.a. |
Neoprontosilosil |
Neoprontosilosil |
AzorDMT |
Neoprontosil transport via proton symport |
NeoProntosilosil[e] + h[e] <=> NeoProntosilosil[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Neoprontosilosil |
Neoprontosilosil |
AzorDMT |
Neoprontosil transport via proton symport, periplasmatic |
h[p] + NeoProntosilosil[p] <=> h[c] + NeoProntosilosil[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Neoprontosilosil |
Neoprontosilosil |
n.a. |
Neoprontosil diffusion extracellular to periplasm |
NeoProntosilosil[e] <=> NeoProntosilosil[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00401 |
Nisoldipine (M5)_Glc |
Nisoldipine (M5) |
UidAc |
Nisoldipine (M5) Glucuronide beta-glucuronidase |
Nisoldipine (M5)_glc[c] + h2o[c] -> Nisoldipine (M5)[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00401 |
Nisoldipine (M5)_Glc |
Nisoldipine (M5) |
UidAe |
Nisoldipine (M5) Glucuronide beta-glucuronidase extracellular |
Nisoldipine (M5)_glc[e] + h2o[e] -> Nisoldipine (M5)[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00401 |
Nisoldipine (M5)_Glc |
Nisoldipine (M5) |
UidAe |
Nisoldipine (M5) Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Nisoldipine (M5)_glc[p] -> glcur[p] + h[p] + Nisoldipine (M5)[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00401 |
Nisoldipine (M5)_Glc |
Nisoldipine (M5)_Glc |
UidABC |
Predicted glucuronide ABC transporter Nisoldipine (M5) Glucuronide |
atp[c] + Nisoldipine (M5)_glc[e] + h2o[c] -> adp[c] + Nisoldipine (M5)_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00401 |
Nisoldipine (M5)_Glc |
Nisoldipine (M5)_Glc |
UidP |
Transport of D-Glucuronate Nisoldipine (M5) Glucuronide |
Nisoldipine (M5)_glc[e] -> Nisoldipine (M5)_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00401 |
Nisoldipine (M5)_Glc |
Nisoldipine (M5)_Glc |
UidB |
Glucuronate transport in via proton symport Nisoldipine (M5) Glucuronide |
Nisoldipine (M5)_glc[e] + h[e] -> Nisoldipine (M5)_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00401 |
Nisoldipine (M5)_Glc |
Nisoldipine (M5)_Glc |
UidB |
Glucuronate transport in via proton symport Nisoldipine (M5) Glucuronide, periplasmatic |
h[p] + Nisoldipine (M5)_glc[p] -> h[c] + Nisoldipine (M5)_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00401 |
Nisoldipine (M5)_Glc |
Nisoldipine (M5)_Glc |
n.a. |
Nisoldipine (M5) Glucuronide diffusion extracellular to periplasm |
Nisoldipine (M5)_glc[e] <=> Nisoldipine (M5)_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00401 |
Nisoldipine (M5) |
Nisoldipine (M5) |
n.a. |
beta-glucuronidase reaction product export Nisoldipine (M5) |
Nisoldipine (M5)[c] -> Nisoldipine (M5)[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00401 |
Nisoldipine (M5) |
Nisoldipine (M5) |
n.a. |
beta-glucuronidase reaction product export Nisoldipine (M5), periplasmatic |
Nisoldipine (M5)[c] -> Nisoldipine (M5)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00401 |
Nisoldipine (M5) |
Nisoldipine (M5) |
n.a. |
Nisoldipine (M5) diffusion extracellular to periplasm |
Nisoldipine (M5)[e] <=> Nisoldipine (M5)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Norverapamil_Glc |
Norverapamil |
UidAc |
Norverapamil Glucuronide beta-glucuronidase |
Norverapamil_glc[c] + h2o[c] + h[c] -> Norverapamil[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Norverapamil_Glc |
Norverapamil |
UidAe |
Norverapamil Glucuronide beta-glucuronidase extracellular |
Norverapamil_glc[e] + h2o[e] + h[e] -> Norverapamil[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Norverapamil_Glc |
Norverapamil |
UidAe |
Norverapamil Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + h[p] + Norverapamil_glc[p] -> glcur[p] + Norverapamil[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Norverapamil_Glc |
Norverapamil_Glc |
UidABC |
Predicted glucuronide ABC transporter Norverapamil Glucuronide |
atp[c] + Norverapamil_glc[e] + h2o[c] -> adp[c] + Norverapamil_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Norverapamil_Glc |
Norverapamil_Glc |
UidP |
Transport of D-Glucuronate Norverapamil Glucuronide |
Norverapamil_glc[e] -> Norverapamil_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Norverapamil_Glc |
Norverapamil_Glc |
UidB |
Glucuronate transport in via proton symport Norverapamil Glucuronide |
Norverapamil_glc[e] + h[e] -> Norverapamil_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Norverapamil_Glc |
Norverapamil_Glc |
UidB |
Glucuronate transport in via proton symport Norverapamil Glucuronide, periplasmatic |
h[p] + Norverapamil_glc[p] -> h[c] + Norverapamil_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Norverapamil_Glc |
Norverapamil_Glc |
n.a. |
Norverapamil Glucuronide diffusion extracellular to periplasm |
Norverapamil_glc[e] <=> Norverapamil_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Norverapamil |
Norverapamil |
n.a. |
beta-glucuronidase reaction product export Norverapamil |
Norverapamil[c] -> Norverapamil[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Norverapamil |
Norverapamil |
n.a. |
beta-glucuronidase reaction product export Norverapamil, periplasmatic |
Norverapamil[c] -> Norverapamil[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Norverapamil |
Norverapamil |
n.a. |
Norverapamil diffusion extracellular to periplasm |
Norverapamil[e] <=> Norverapamil[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01595 |
Nitrazepam, Benzalin, Neozepam |
7-Amino Nitrozepam |
Nit |
Nitrazepam Microbiota nitroreduction |
Nitrazepam, Benzalin, Neozepam[c] + 3 nadph[c] + 3 h[c] <=> 7-Amino Nitrozepam[c] + 3 nadp[c] + 2 h2o[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 9310649, PMID: 22445794, PMID: 26261284 |
| DB01595 |
Nitrazepam, Benzalin, Neozepam |
7-Amino Nitrozepam |
eNit |
Nitrazepam Microbiota nitroreduction |
Nitrazepam, Benzalin, Neozepam[e] + 3 nadph[e] + 3 h[c] <=> 7-Amino Nitrozepam[e] + 3 nadp[e] + 2 h2o[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 9310649, PMID: 22445794, PMID: 26261284 |
| DB01595 |
Nitrazepam, Benzalin, Neozepam |
7-Amino Nitrozepam |
eNit |
Nitrazepam Microbiota nitroreduction irreversible |
Nitrazepam, Benzalin, Neozepam[e] + 3 nadph[e] + 3 h[c] <=> 7-Amino Nitrozepam[e] + 3 nadp[e] + 2 h2o[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 9310649, PMID: 22445794, PMID: 26261284 |
| DB01595 |
Nitrazepam, Benzalin, Neozepam |
7-Amino Nitrozepam |
eNit |
Nitrazepam Microbiota nitroreduction, irreversible, periplasmatic |
3 nadph[c] + 3 h[p] + Nitrazepam, Benzalin, Neozepam[p] -> 3 nadp[c] + 7-Amino Nitrozepam[p] + 2 h2o[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01595 |
Nitrazepam, Benzalin, Neozepam |
7-Amino Nitrozepam |
eNit |
Nitrazepam Microbiota nitroreduction, periplasmatic |
3 nadph[c] + 3 h[p] + Nitrazepam, Benzalin, Neozepam[p] <=> 3 nadp[c] + 7-Amino Nitrozepam[p] + 2 h2o[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01595 |
Nitrazepam, Benzalin, Neozepam |
Nitrazepam, Benzalin, Neozepam |
n.a. |
Nitrazepam, Benzalin, Neozepam diffusion extracellular to periplasm |
Nitrazepam, Benzalin, Neozepam[e] <=> Nitrazepam, Benzalin, Neozepam[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00674 |
Odsm_Egalantamine_Glc |
Odsm_Egalantamine |
UidAc |
O-Desmethylepigalantamine Glucuronide beta-glucuronidase |
odsm_eGalantamine_glc[c] + h2o[c] -> odsm_eGalantamine[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00674 |
Odsm_Egalantamine_Glc |
Odsm_Egalantamine |
UidAe |
O-Desmethylepigalantamine Glucuronide beta-glucuronidase extracellular |
odsm_eGalantamine_glc[e] + h2o[e] -> odsm_eGalantamine[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00674 |
Odsm_Egalantamine_Glc |
Odsm_Egalantamine |
UidAe |
O-Desmethylepigalantamine Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + odsm_eGalantamine_glc[p] -> glcur[p] + odsm_eGalantamine[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00674 |
Odsm_Egalantamine_Glc |
Odsm_Egalantamine_Glc |
UidABC |
Predicted glucuronide ABC transporter O-Desmethylepigalantamine Glucuronide |
atp[c] + odsm_eGalantamine_glc[e] + h2o[c] -> adp[c] + odsm_eGalantamine_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00674 |
Odsm_Egalantamine_Glc |
Odsm_Egalantamine_Glc |
UidP |
Transport of D-Glucuronate O-Desmethylepigalantamine Glucuronide |
odsm_eGalantamine_glc[e] -> odsm_eGalantamine_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00674 |
Odsm_Egalantamine_Glc |
Odsm_Egalantamine_Glc |
UidB |
Glucuronate transport in via proton symport O-Desmethylepigalantamine Glucuronide |
odsm_eGalantamine_glc[e] + h[e] -> odsm_eGalantamine_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00674 |
Odsm_Egalantamine_Glc |
Odsm_Egalantamine_Glc |
UidB |
Glucuronate transport in via proton symport O-Desmethylepigalantamine Glucuronide, periplasmatic |
h[p] + odsm_eGalantamine_glc[p] -> h[c] + odsm_eGalantamine_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00674 |
Odsm_Egalantamine_Glc |
Odsm_Egalantamine_Glc |
n.a. |
O-Desmethylepigalantamine Glucuronide diffusion extracellular to periplasm |
odsm_eGalantamine_glc[e] <=> odsm_eGalantamine_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00674 |
Odsm_Egalantamine |
Odsm_Egalantamine |
n.a. |
beta-glucuronidase reaction product export O-Desmethylepigalantamine |
odsm_eGalantamine[c] -> odsm_eGalantamine[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00674 |
Odsm_Egalantamine |
Odsm_Egalantamine |
n.a. |
beta-glucuronidase reaction product export O-Desmethylepigalantamine, periplasmatic |
odsm_eGalantamine[c] -> odsm_eGalantamine[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00674 |
Odsm_Egalantamine |
Odsm_Egalantamine |
n.a. |
O-Desmethylepigalantamine diffusion extracellular to periplasm |
odsm_eGalantamine[e] <=> odsm_eGalantamine[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00674 |
Odsm_Galantamine_Glc |
Odsm_Galantamine |
UidAc |
O-Desmethylgalantamine Glucuronide beta-glucuronidase |
odsm_Galantamine_glc[c] + h2o[c] -> odsm_Galantamine[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00674 |
Odsm_Galantamine_Glc |
Odsm_Galantamine |
UidAe |
O-Desmethylgalantamine Glucuronide beta-glucuronidase extracellular |
odsm_Galantamine_glc[e] + h2o[e] -> odsm_Galantamine[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00674 |
Odsm_Galantamine_Glc |
Odsm_Galantamine |
UidAe |
O-Desmethylgalantamine Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + odsm_Galantamine_glc[p] -> glcur[p] + odsm_Galantamine[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00674 |
Odsm_Galantamine_Glc |
Odsm_Galantamine_Glc |
UidABC |
Predicted glucuronide ABC transporter O-Desmethylgalantamine Glucuronide |
atp[c] + odsm_Galantamine_glc[e] + h2o[c] -> adp[c] + odsm_Galantamine_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00674 |
Odsm_Galantamine_Glc |
Odsm_Galantamine_Glc |
UidP |
Transport of D-Glucuronate O-Desmethylgalantamine Glucuronide |
odsm_Galantamine_glc[e] -> odsm_Galantamine_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00674 |
Odsm_Galantamine_Glc |
Odsm_Galantamine_Glc |
UidB |
Glucuronate transport in via proton symport O-Desmethylgalantamine Glucuronide |
odsm_Galantamine_glc[e] + h[e] -> odsm_Galantamine_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00674 |
Odsm_Galantamine_Glc |
Odsm_Galantamine_Glc |
UidB |
Glucuronate transport in via proton symport O-Desmethylgalantamine Glucuronide, periplasmatic |
h[p] + odsm_Galantamine_glc[p] -> h[c] + odsm_Galantamine_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00674 |
Odsm_Galantamine_Glc |
Odsm_Galantamine_Glc |
n.a. |
O-Desmethylgalantamine Glucuronide diffusion extracellular to periplasm |
odsm_Galantamine_glc[e] <=> odsm_Galantamine_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00674 |
Odsm_Galantamine |
Odsm_Galantamine |
n.a. |
beta-glucuronidase reaction product export O-Desmethylgalantamine |
odsm_Galantamine[c] -> odsm_Galantamine[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00674 |
Odsm_Galantamine |
Odsm_Galantamine |
n.a. |
beta-glucuronidase reaction product export O-Desmethylgalantamine, periplasmatic |
odsm_Galantamine[c] -> odsm_Galantamine[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00674 |
Odsm_Galantamine |
Odsm_Galantamine |
n.a. |
O-Desmethylgalantamine diffusion extracellular to periplasm |
odsm_Galantamine[e] <=> odsm_Galantamine[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB06414 |
Etravarine Monohydroxylated (M1, M2, M3)_Glc |
Etravarine Monohydroxylated (M1, M2, M3) |
UidAc |
Etravarine Monohydroxylated Glucuronide (M7) beta-glucuronidase |
Etravarine Monohydroxylated (M1, M2, M3)_glc[c] + h2o[c] -> Etravarine Monohydroxylated (M1, M2, M3)[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB06414 |
Etravarine Monohydroxylated (M1, M2, M3)_Glc |
Etravarine Monohydroxylated (M1, M2, M3) |
UidAe |
Etravarine Monohydroxylated Glucuronide (M7) beta-glucuronidase extracellular |
Etravarine Monohydroxylated (M1, M2, M3)_glc[e] + h2o[e] -> Etravarine Monohydroxylated (M1, M2, M3)[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB06414 |
Etravarine Monohydroxylated (M1, M2, M3)_Glc |
Etravarine Monohydroxylated (M1, M2, M3) |
UidAe |
Etravarine Monohydroxylated Glucuronide (M7) beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Etravarine Monohydroxylated (M1, M2, M3)_glc[p] -> glcur[p] + h[p] + Etravarine Monohydroxylated (M1, M2, M3)[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB06414 |
Etravarine Monohydroxylated (M1, M2, M3)_Glc |
Etravarine Monohydroxylated (M1, M2, M3)_Glc |
UidABC |
Predicted glucuronide ABC transporter Etravarine Monohydroxylated Glucuronide (M7) |
atp[c] + Etravarine Monohydroxylated (M1, M2, M3)_glc[e] + h2o[c] -> adp[c] + Etravarine Monohydroxylated (M1, M2, M3)_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB06414 |
Etravarine Monohydroxylated (M1, M2, M3)_Glc |
Etravarine Monohydroxylated (M1, M2, M3)_Glc |
UidP |
Transport of D-Glucuronate Etravarine Monohydroxylated Glucuronide (M7) |
Etravarine Monohydroxylated (M1, M2, M3)_glc[e] -> Etravarine Monohydroxylated (M1, M2, M3)_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB06414 |
Etravarine Monohydroxylated (M1, M2, M3)_Glc |
Etravarine Monohydroxylated (M1, M2, M3)_Glc |
UidB |
Glucuronate transport in via proton symport Etravarine Monohydroxylated Glucuronide (M7) |
Etravarine Monohydroxylated (M1, M2, M3)_glc[e] + h[e] -> Etravarine Monohydroxylated (M1, M2, M3)_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB06414 |
Etravarine Monohydroxylated (M1, M2, M3)_Glc |
Etravarine Monohydroxylated (M1, M2, M3)_Glc |
UidB |
Glucuronate transport in via proton symport Etravarine Monohydroxylated Glucuronide (M7), periplasmatic |
h[p] + Etravarine Monohydroxylated (M1, M2, M3)_glc[p] -> h[c] + Etravarine Monohydroxylated (M1, M2, M3)_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB06414 |
Etravarine Monohydroxylated (M1, M2, M3)_Glc |
Etravarine Monohydroxylated (M1, M2, M3)_Glc |
n.a. |
Etravarine Monohydroxylated Glucuronide (M7) diffusion extracellular to periplasm |
Etravarine Monohydroxylated (M1, M2, M3)_glc[e] <=> Etravarine Monohydroxylated (M1, M2, M3)_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB06414 |
Etravarine Monohydroxylated (M1, M2, M3) |
Etravarine Monohydroxylated (M1, M2, M3) |
n.a. |
beta-glucuronidase reaction product export Etravarine Monohydroxylated (M1 M2 M3) |
Etravarine Monohydroxylated (M1, M2, M3)[c] -> Etravarine Monohydroxylated (M1, M2, M3)[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB06414 |
Etravarine Monohydroxylated (M1, M2, M3) |
Etravarine Monohydroxylated (M1, M2, M3) |
n.a. |
beta-glucuronidase reaction product export Etravarine Monohydroxylated (M1 M2 M3), periplasmatic |
Etravarine Monohydroxylated (M1, M2, M3)[c] -> Etravarine Monohydroxylated (M1, M2, M3)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB06414 |
Etravarine Monohydroxylated (M1, M2, M3) |
Etravarine Monohydroxylated (M1, M2, M3) |
n.a. |
Etravarine Monohydroxylated (M1, M2, M3) diffusion extracellular to periplasm |
Etravarine Monohydroxylated (M1, M2, M3)[e] <=> Etravarine Monohydroxylated (M1, M2, M3)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01174 |
P-Hydroxyphenobarbital_Glc |
P-Hydroxyphenobarbital |
UidAc |
Phenobarbital O-Glucuronide beta-glucuronidase |
P-Hydroxyphenobarbital_glc[c] + h2o[c] -> P-Hydroxyphenobarbital[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01174 |
P-Hydroxyphenobarbital_Glc |
P-Hydroxyphenobarbital |
UidAe |
Phenobarbital O-Glucuronide beta-glucuronidase extracellular |
P-Hydroxyphenobarbital_glc[e] + h2o[e] -> P-Hydroxyphenobarbital[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01174 |
P-Hydroxyphenobarbital_Glc |
P-Hydroxyphenobarbital |
UidAe |
Phenobarbital O-Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + P-Hydroxyphenobarbital_glc[p] -> glcur[p] + P-Hydroxyphenobarbital[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01174 |
P-Hydroxyphenobarbital_Glc |
P-Hydroxyphenobarbital_Glc |
UidABC |
Predicted glucuronide ABC transporter Phenobarbital O-Glucuronide |
atp[c] + P-Hydroxyphenobarbital_glc[e] + h2o[c] -> adp[c] + P-Hydroxyphenobarbital_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01174 |
P-Hydroxyphenobarbital_Glc |
P-Hydroxyphenobarbital_Glc |
UidP |
Transport of D-Glucuronate Phenobarbital O-Glucuronide |
P-Hydroxyphenobarbital_glc[e] -> P-Hydroxyphenobarbital_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01174 |
P-Hydroxyphenobarbital_Glc |
P-Hydroxyphenobarbital_Glc |
UidB |
Glucuronate transport in via proton symport Phenobarbital O-Glucuronide |
P-Hydroxyphenobarbital_glc[e] + h[e] -> P-Hydroxyphenobarbital_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01174 |
P-Hydroxyphenobarbital_Glc |
P-Hydroxyphenobarbital_Glc |
UidB |
Glucuronate transport in via proton symport Phenobarbital O-Glucuronide, periplasmatic |
h[p] + P-Hydroxyphenobarbital_glc[p] -> h[c] + P-Hydroxyphenobarbital_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01174 |
P-Hydroxyphenobarbital_Glc |
P-Hydroxyphenobarbital_Glc |
n.a. |
Phenobarbital O-Glucuronide diffusion extracellular to periplasm |
P-Hydroxyphenobarbital_glc[e] <=> P-Hydroxyphenobarbital_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01174 |
P-Hydroxyphenobarbital |
P-Hydroxyphenobarbital |
n.a. |
beta-glucuronidase reaction product export P-Hydroxyphenobarbital |
P-Hydroxyphenobarbital[c] -> P-Hydroxyphenobarbital[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01174 |
P-Hydroxyphenobarbital |
P-Hydroxyphenobarbital |
n.a. |
beta-glucuronidase reaction product export P-Hydroxyphenobarbital, periplasmatic |
P-Hydroxyphenobarbital[c] -> P-Hydroxyphenobarbital[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01174 |
P-Hydroxyphenobarbital |
P-Hydroxyphenobarbital |
n.a. |
P-Hydroxyphenobarbital diffusion extracellular to periplasm |
P-Hydroxyphenobarbital[e] <=> P-Hydroxyphenobarbital[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01250 |
Olsalazine |
N.A. |
AzNAD |
Olsalazine Microbiota azo-reduction (NAD) |
Olsalazine[c] + 2 nadh[c] + 2 h[c] <=> 2 5-Aminosalicylic Acid (Mesalamine)[c] + 2 nad[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 25091594, PMID: 26261286 |
| DB01250 |
Olsalazine |
N.A. |
AzNADP |
Olsalazine Microbiota azo-reduction (NADP) |
Olsalazine[c] + 2 nadph[c] + 2 h[c] <=> 2 5-Aminosalicylic Acid (Mesalamine)[c] + 2 nadp[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 25091594, PMID: 26261286 |
| DB01250 |
Olsalazine |
Olsalazine |
AzorDMT |
Olsalazine transport via proton symport |
Olsalazine[e] + h[e] <=> Olsalazine[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01250 |
Olsalazine |
Olsalazine |
AzorDMT |
Olsalazine transport via proton symport, periplasmatic |
h[p] + Olsalazine[p] <=> h[c] + Olsalazine[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01250 |
Olsalazine |
Olsalazine |
n.a. |
Olsalazine diffusion extracellular to periplasm |
Olsalazine[e] <=> Olsalazine[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
P-Cresol |
P-Cresol |
Hpd |
P-cresol transport via proton symport |
h[e] + p-Cresol[e] <=> h[c] + p-Cresol[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
3-(3-Hydroxyphenyl)Propionate_Glc |
3-(3-Hydroxyphenyl)Propionate |
UidAc |
3-(3-Hydroxyphenyl)Propionate Glucuronide beta-glucuronidase |
3-(3-Hydroxyphenyl)Propionate_glc[c] + h2o[c] -> 3-(3-Hydroxyphenyl)Propionate[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
3-(3-Hydroxyphenyl)Propionate_Glc |
3-(3-Hydroxyphenyl)Propionate |
UidAe |
3-(3-hydroxyphenyl)propionate glucuronide beta-glucuronidase extracellular |
3-(3-Hydroxyphenyl)Propionate_glc[e] + h2o[e] -> 3-(3-Hydroxyphenyl)Propionate[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
3-(3-Hydroxyphenyl)Propionate_Glc |
3-(3-Hydroxyphenyl)Propionate |
UidAe |
3-(3-hydroxyphenyl)propionate glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + 3-(3-Hydroxyphenyl)Propionate_glc[p] -> glcur[p] + 3-(3-Hydroxyphenyl)Propionate[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
3-(3-Hydroxyphenyl)Propionate_Glc |
3-(3-Hydroxyphenyl)Propionate_Glc |
UidABC |
Predicted glucuronide ABC transporter 3-(3-Hydroxyphenyl)Propionate Glucuronide |
atp[c] + 3-(3-Hydroxyphenyl)Propionate_glc[e] + h2o[c] -> adp[c] + 3-(3-Hydroxyphenyl)Propionate_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
3-(3-Hydroxyphenyl)Propionate_Glc |
3-(3-Hydroxyphenyl)Propionate_Glc |
UidP |
Transport of D-Glucuronate 3-(3-hydroxyphenyl)propionate glucuronide |
3-(3-Hydroxyphenyl)Propionate_glc[e] -> 3-(3-Hydroxyphenyl)Propionate_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
3-(3-Hydroxyphenyl)Propionate_Glc |
3-(3-Hydroxyphenyl)Propionate_Glc |
UidB |
Glucuronate transport in via proton symport 3-(3-Hydroxyphenyl)Propionate Glucuronide |
3-(3-Hydroxyphenyl)Propionate_glc[e] + h[e] -> 3-(3-Hydroxyphenyl)Propionate_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
3-(3-Hydroxyphenyl)Propionate_Glc |
3-(3-Hydroxyphenyl)Propionate_Glc |
UidB |
Glucuronate transport in via proton symport 3-(3-Hydroxyphenyl)Propionate Glucuronide, periplasmatic |
h[p] + 3-(3-Hydroxyphenyl)Propionate_glc[p] -> h[c] + 3-(3-Hydroxyphenyl)Propionate_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
3-(3-Hydroxyphenyl)Propionate_Glc |
3-(3-Hydroxyphenyl)Propionate_Glc |
n.a. |
3-(3-Hydroxyphenyl)Propionate Glucuronide diffusion extracellular to periplasm |
3-(3-Hydroxyphenyl)Propionate_glc[e] <=> 3-(3-Hydroxyphenyl)Propionate_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
3-(3-Hydroxyphenyl)Propionate |
3-(3-Hydroxyphenyl)Propionate |
n.a. |
beta-glucuronidase reaction product export 3-(3-hydroxyphenyl)propionate |
3-(3-Hydroxyphenyl)Propionate[c] -> 3-(3-Hydroxyphenyl)Propionate[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB03783 |
Phenacetin Glucuronide |
N-Hydroxylated Phenacetin |
UidAc |
Phenacetin Glucuronide beta-glucuronidase |
Phenacetin Glucuronide[c] + h2o[c] -> N-Hydroxylated Phenacetin[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB03783 |
Phenacetin Glucuronide |
N-Hydroxylated Phenacetin |
UidAe |
Phenacetin Glucuronide beta-glucuronidase extracellular |
Phenacetin Glucuronide[e] + h2o[e] -> N-Hydroxylated Phenacetin[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB03783 |
Phenacetin Glucuronide |
N-Hydroxylated Phenacetin |
UidAe |
Phenacetin Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Phenacetin Glucuronide[p] -> N-Hydroxylated Phenacetin[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB03783 |
Phenacetin Glucuronide |
Phenacetin Glucuronide |
UidABC |
Predicted glucuronide ABC transporter Phenacetin Glucuronide |
atp[c] + Phenacetin Glucuronide[e] + h2o[c] -> adp[c] + Phenacetin Glucuronide[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB03783 |
Phenacetin Glucuronide |
Phenacetin Glucuronide |
UidP |
Transport of D-Glucuronate Phenacetin Glucuronide |
Phenacetin Glucuronide[e] -> Phenacetin Glucuronide[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB03783 |
Phenacetin Glucuronide |
Phenacetin Glucuronide |
UidB |
Glucuronate transport in via proton symport Phenacetin Glucuronide |
Phenacetin Glucuronide[e] + h[e] -> Phenacetin Glucuronide[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB03783 |
Phenacetin Glucuronide |
Phenacetin Glucuronide |
UidB |
Glucuronate transport in via proton symport Phenacetin Glucuronide, periplasmatic |
h[p] + Phenacetin Glucuronide[p] -> h[c] + Phenacetin Glucuronide[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB03783 |
Phenacetin Glucuronide |
Phenacetin Glucuronide |
n.a. |
Phenacetin Glucuronide diffusion extracellular to periplasm |
Phenacetin Glucuronide[e] <=> Phenacetin Glucuronide[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01032 |
Probenecid_Glc |
Probenecid |
UidAc |
Probenecid Acyl Beta-D-Glucuronide beta-glucuronidase |
Probenecid_glc[c] + h2o[c] -> Probenecid[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01032 |
Probenecid_Glc |
Probenecid |
UidAe |
Probenecid Acyl Beta-D-Glucuronide beta-glucuronidase extracellular |
Probenecid_glc[e] + h2o[e] -> Probenecid[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01032 |
Probenecid_Glc |
Probenecid |
UidAe |
Probenecid Acyl Beta-D-Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Probenecid_glc[p] -> glcur[p] + h[p] + Probenecid[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01032 |
Probenecid_Glc |
Probenecid_Glc |
UidABC |
Predicted glucuronide ABC transporter Probenecid Acyl Beta-D-Glucuronide |
atp[c] + Probenecid_glc[e] + h2o[c] -> adp[c] + Probenecid_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01032 |
Probenecid_Glc |
Probenecid_Glc |
UidP |
Transport of D-Glucuronate Probenecid Acyl Beta-D-Glucuronide |
Probenecid_glc[e] -> Probenecid_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01032 |
Probenecid_Glc |
Probenecid_Glc |
UidB |
Glucuronate transport in via proton symport Probenecid Acyl Beta-D-Glucuronide |
Probenecid_glc[e] + h[e] -> Probenecid_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01032 |
Probenecid_Glc |
Probenecid_Glc |
UidB |
Glucuronate transport in via proton symport Probenecid Acyl Beta-D-Glucuronide, periplasmatic |
h[p] + Probenecid_glc[p] -> h[c] + Probenecid_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01032 |
Probenecid_Glc |
Probenecid_Glc |
n.a. |
Probenecid Acyl Beta-D-Glucuronide diffusion extracellular to periplasm |
Probenecid_glc[e] <=> Probenecid_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01032 |
Probenecid |
Probenecid |
n.a. |
beta-glucuronidase reaction product export Probenecid |
Probenecid[c] -> Probenecid[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01032 |
Probenecid |
Probenecid |
n.a. |
beta-glucuronidase reaction product export Probenecid, periplasmatic |
Probenecid[c] -> Probenecid[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01032 |
Probenecid |
Probenecid |
n.a. |
Probenecid diffusion extracellular to periplasm |
Probenecid[e] <=> Probenecid[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Prontosil |
1,2,4-Triaminobenzene |
AzNAD |
Prontosil Microbiota azo-reduction (NAD) |
Prontosil[c] + 2 nadh[c] + 2 h[c] <=> 1,2,4-Triaminobenzene[c] + Sulfanilamide[c] + 2 nad[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 5173017, PMID: 26261286 |
| n.a. |
Prontosil |
1,2,4-Triaminobenzene |
AzNADP |
Prontosil Microbiota azo-reduction (NADP) |
Prontosil[c] + 2 nadph[c] + 2 h[c] <=> 1,2,4-Triaminobenzene[c] + Sulfanilamide[c] + 2 nadp[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 5173017, PMID: 26261286 |
| n.a. |
Prontosil_Glc |
Prontosil |
UidAc |
Prontosil Glucuronide beta-glucuronidase |
Prontosil_glc[c] + h2o[c] -> Prontosil[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Prontosil_Glc |
Prontosil |
UidAe |
Prontosil Glucuronide beta-glucuronidase extracellular |
Prontosil_glc[e] + h2o[e] -> Prontosil[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Prontosil_Glc |
Prontosil |
UidAe |
Prontosil Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Prontosil_glc[p] -> glcur[p] + Prontosil[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Prontosil_Glc |
Prontosil_Glc |
UidABC |
Predicted glucuronide ABC transporter Prontosil Glucuronide |
atp[c] + Prontosil_glc[e] + h2o[c] -> adp[c] + Prontosil_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Prontosil_Glc |
Prontosil_Glc |
UidP |
Transport of D-Glucuronate Prontosil Glucuronide |
Prontosil_glc[e] -> Prontosil_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Prontosil_Glc |
Prontosil_Glc |
UidB |
Glucuronate transport in via proton symport Prontosil Glucuronide |
Prontosil_glc[e] + h[e] -> Prontosil_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Prontosil_Glc |
Prontosil_Glc |
UidB |
Glucuronate transport in via proton symport Prontosil Glucuronide, periplasmatic |
h[p] + Prontosil_glc[p] -> h[c] + Prontosil_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Prontosil_Glc |
Prontosil_Glc |
n.a. |
Prontosil Glucuronide diffusion extracellular to periplasm |
Prontosil_glc[e] <=> Prontosil_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Prontosil |
Prontosil |
AzorDMT |
Prontosil transport via proton symport |
Prontosil[e] + h[e] <=> Prontosil[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Prontosil |
Prontosil |
AzorDMT |
Prontosil transport via proton symport, periplasmatic |
h[p] + Prontosil[p] <=> h[c] + Prontosil[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Prontosil |
Prontosil |
n.a. |
beta-glucuronidase reaction product export Prontosil |
Prontosil[c] -> Prontosil[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Prontosil |
Prontosil |
n.a. |
beta-glucuronidase reaction product export Prontosil, periplasmatic |
Prontosil[c] -> Prontosil[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Prontosil |
Prontosil |
n.a. |
Prontosil diffusion extracellular to periplasm |
Prontosil[e] <=> Prontosil[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00172 |
Proline |
N.A. |
n.a. |
Transport of Proline via Pat4, periplasmatic |
pro_L[p] <=> pro_L[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00571 |
Propranolol_Glc |
Propranolol |
UidAc |
Propranolol Glucuronide beta-glucuronidase |
Propranolol_glc[c] + h2o[c] -> Propranolol[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00571 |
Propranolol_Glc |
Propranolol |
UidAe |
Propranolol Glucuronide beta-glucuronidase extracellular |
Propranolol_glc[e] + h2o[e] -> Propranolol[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00571 |
Propranolol_Glc |
Propranolol |
UidAe |
Propranolol Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Propranolol_glc[p] -> glcur[p] + Propranolol[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00571 |
Propranolol_Glc |
Propranolol_Glc |
UidABC |
Predicted glucuronide ABC transporter Propranolol Glucuronide |
atp[c] + Propranolol_glc[e] + h2o[c] -> adp[c] + Propranolol_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00571 |
Propranolol_Glc |
Propranolol_Glc |
UidP |
Transport of D-Glucuronate Propranolol Glucuronide |
Propranolol_glc[e] -> Propranolol_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00571 |
Propranolol_Glc |
Propranolol_Glc |
UidB |
Glucuronate transport in via proton symport Propranolol Glucuronide |
Propranolol_glc[e] + h[e] -> Propranolol_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00571 |
Propranolol_Glc |
Propranolol_Glc |
UidB |
Glucuronate transport in via proton symport Propranolol Glucuronide, periplasmatic |
h[p] + Propranolol_glc[p] -> h[c] + Propranolol_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00571 |
Propranolol_Glc |
Propranolol_Glc |
n.a. |
Propranolol Glucuronide diffusion extracellular to periplasm |
Propranolol_glc[e] <=> Propranolol_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00571 |
Propranolol |
Propranolol |
n.a. |
beta-glucuronidase reaction product export Propranolol |
Propranolol[c] -> Propranolol[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00571 |
Propranolol |
Propranolol |
n.a. |
beta-glucuronidase reaction product export Propranolol, periplasmatic |
Propranolol[c] -> Propranolol[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00571 |
Propranolol |
Propranolol |
n.a. |
Propranolol diffusion extracellular to periplasm |
Propranolol[e] <=> Propranolol[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00715 |
Paroxetine Mi_Glc |
Paroxetine Mi |
UidAc |
Paroxetine Mi Glucuronide beta-glucuronidase |
Paroxetine Mi_glc[c] + h2o[c] -> Paroxetine Mi[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00715 |
Paroxetine Mi_Glc |
Paroxetine Mi |
UidAe |
Paroxetine Mi Glucuronide beta-glucuronidase extracellular |
Paroxetine Mi_glc[e] + h2o[e] -> Paroxetine Mi[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00715 |
Paroxetine Mi_Glc |
Paroxetine Mi |
UidAe |
Paroxetine Mi Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Paroxetine Mi_glc[p] -> glcur[p] + h[p] + Paroxetine Mi[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00715 |
Paroxetine Mi_Glc |
Paroxetine Mi_Glc |
UidABC |
Predicted glucuronide ABC transporter Paroxetine Mi Glucuronide |
atp[c] + Paroxetine Mi_glc[e] + h2o[c] -> adp[c] + Paroxetine Mi_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00715 |
Paroxetine Mi_Glc |
Paroxetine Mi_Glc |
UidP |
Transport of D-Glucuronate Paroxetine Mi Glucuronide |
Paroxetine Mi_glc[e] -> Paroxetine Mi_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00715 |
Paroxetine Mi_Glc |
Paroxetine Mi_Glc |
UidB |
Glucuronate transport in via proton symport Paroxetine Mi Glucuronide |
Paroxetine Mi_glc[e] + h[e] -> Paroxetine Mi_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00715 |
Paroxetine Mi_Glc |
Paroxetine Mi_Glc |
UidB |
Glucuronate transport in via proton symport Paroxetine Mi Glucuronide, periplasmatic |
h[p] + Paroxetine Mi_glc[p] -> h[c] + Paroxetine Mi_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00715 |
Paroxetine Mi_Glc |
Paroxetine Mi_Glc |
n.a. |
Paroxetine Mi Glucuronide diffusion extracellular to periplasm |
Paroxetine Mi_glc[e] <=> Paroxetine Mi_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00715 |
Paroxetine Mii_Glc |
Paroxetine Mii |
UidAc |
Paroxetine Mii Glucuronide beta-glucuronidase |
Paroxetine MiI_glc[c] + h2o[c] -> Paroxetine MiI[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00715 |
Paroxetine Mii_Glc |
Paroxetine Mii |
UidAe |
Paroxetine Mii Glucuronide beta-glucuronidase extracellular |
Paroxetine MiI_glc[e] + h2o[e] -> Paroxetine MiI[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00715 |
Paroxetine Mii_Glc |
Paroxetine Mii |
UidAe |
Paroxetine Mii Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Paroxetine MiI_glc[p] -> glcur[p] + h[p] + Paroxetine MiI[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00715 |
Paroxetine Mii_Glc |
Paroxetine Mii_Glc |
UidABC |
Predicted glucuronide ABC transporter Paroxetine Mii Glucuronide |
atp[c] + Paroxetine MiI_glc[e] + h2o[c] -> adp[c] + Paroxetine MiI_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00715 |
Paroxetine Mii_Glc |
Paroxetine Mii_Glc |
UidP |
Transport of D-Glucuronate Paroxetine Mii Glucuronide |
Paroxetine MiI_glc[e] -> Paroxetine MiI_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00715 |
Paroxetine Mii_Glc |
Paroxetine Mii_Glc |
UidB |
Glucuronate transport in via proton symport Paroxetine Mii Glucuronide |
Paroxetine MiI_glc[e] + h[e] -> Paroxetine MiI_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00715 |
Paroxetine Mii_Glc |
Paroxetine Mii_Glc |
UidB |
Glucuronate transport in via proton symport Paroxetine Mii Glucuronide, periplasmatic |
h[p] + Paroxetine MiI_glc[p] -> h[c] + Paroxetine MiI_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00715 |
Paroxetine Mii_Glc |
Paroxetine Mii_Glc |
n.a. |
Paroxetine Mii Glucuronide diffusion extracellular to periplasm |
Paroxetine MiI_glc[e] <=> Paroxetine MiI_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00715 |
Paroxetine Mii |
Paroxetine Mii |
n.a. |
beta-glucuronidase reaction product export Paroxetine Mii |
Paroxetine MiI[c] -> Paroxetine MiI[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00715 |
Paroxetine Mii |
Paroxetine Mii |
n.a. |
beta-glucuronidase reaction product export Paroxetine Mii, periplasmatic |
Paroxetine MiI[c] -> Paroxetine MiI[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00715 |
Paroxetine Mii |
Paroxetine Mii |
n.a. |
Paroxetine Mii diffusion extracellular to periplasm |
Paroxetine MiI[e] <=> Paroxetine MiI[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00715 |
Paroxetine Mi |
Paroxetine Mi |
n.a. |
beta-glucuronidase reaction product export Paroxetine Mi |
Paroxetine Mi[c] -> Paroxetine Mi[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00715 |
Paroxetine Mi |
Paroxetine Mi |
n.a. |
beta-glucuronidase reaction product export Paroxetine Mi, periplasmatic |
Paroxetine Mi[c] -> Paroxetine Mi[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00715 |
Paroxetine Mi |
Paroxetine Mi |
n.a. |
Paroxetine Mi diffusion extracellular to periplasm |
Paroxetine Mi[e] <=> Paroxetine Mi[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB08860 |
Pitavasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
N.A. |
UidAc |
pitavastatin-glucuronide beta-glucuronidase |
pitavasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[c] -> pitavasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinlac[c] + 2 glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB08860 |
Pitavasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
N.A. |
UidAe |
pitavastatin-glucuronide beta-glucuronidase extracellular |
pitavasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[e] -> pitavasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidinlac[e] + 2 glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB08860 |
Pitavasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
Pitavasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
UidAe |
pitavastatin-glucuronide beta-glucuronidase extracellular, periplasmatic |
2 h2o[p] + pitavasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[p] -> 2 glcur[p] + 2 h[p] + pitavasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB08860 |
Pitavasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
Pitavasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
UidABC |
Predicted glucuronide ABC transporter pitavastatin-glucuronide |
atp[c] + pitavasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[e] + h2o[c] -> adp[c] + pitavasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB08860 |
Pitavasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
Pitavasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
UidP |
Transport of D-Glucuronate pitavastatin-glucuronide |
pitavasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[e] -> pitavasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB08860 |
Pitavasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
Pitavasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
UidB |
Glucuronate transport in via proton symport pitavastatin-glucuronide |
pitavasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[e] + h[e] -> pitavasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB08860 |
Pitavasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
Pitavasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
UidB |
Glucuronate transport in via proton symport pitavastatin-glucuronide, periplasmatic |
h[p] + pitavasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[p] -> h[c] + pitavasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB08860 |
Pitavasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
Pitavasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
n.a. |
pitavastatin-glucuronide diffusion extracellular to periplasm |
pitavasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[e] <=> pitavasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB08860 |
Pitavasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
Pitavasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
n.a. |
beta-glucuronidase reaction product export pitavastatin |
pitavasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[c] -> pitavasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB08860 |
Pitavasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
Pitavasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
n.a. |
beta-glucuronidase reaction product export pitavastatin, periplasmatic |
pitavasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[c] -> pitavasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB08860 |
Pitavasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
Pitavasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
n.a. |
pitavastatin diffusion extracellular to periplasm |
pitavasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[e] <=> pitavasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00175 |
Pravasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
Pravasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
UidAc |
pravastatin glucuronide beta-glucuronidase |
pravasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[c] + h2o[c] -> pravasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00175 |
Pravasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
Pravasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
UidAe |
pravastatin glucuronide beta-glucuronidase extracellular |
pravasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[e] + h2o[e] -> pravasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00175 |
Pravasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
Pravasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
UidAe |
pravastatin glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + pravasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[p] -> glcur[p] + pravasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00175 |
Pravasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
Pravasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
UidABC |
Predicted glucuronide ABC transporter pravastatin glucuronide |
atp[c] + pravasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[e] + h2o[c] -> adp[c] + pravasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00175 |
Pravasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
Pravasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
UidP |
Transport of D-Glucuronate pravastatin glucuronide |
pravasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[e] -> pravasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00175 |
Pravasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
Pravasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
UidB |
Glucuronate transport in via proton symport pravastatin glucuronide |
pravasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[e] + h[e] -> pravasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00175 |
Pravasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
Pravasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
UidB |
Glucuronate transport in via proton symport pravastatin glucuronide, periplasmatic |
h[p] + pravasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[p] -> h[c] + pravasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00175 |
Pravasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
Pravasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
n.a. |
pravastatin glucuronide diffusion extracellular to periplasm |
pravasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[e] <=> pravasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00175 |
Pravasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
Pravasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
n.a. |
beta-glucuronidase reaction product export pravastatin |
pravasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[c] -> pravasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00175 |
Pravasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
Pravasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
n.a. |
beta-glucuronidase reaction product export pravastatin, periplasmatic |
pravasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[c] -> pravasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00175 |
Pravasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
Pravasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
n.a. |
pravastatin diffusion extracellular to periplasm |
pravasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[e] <=> pravasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB03312 |
Brivudine |
2 (E)-5-(2-Bromovinyl)Uracil |
Pdp |
Pyrimidine-Nucleoside Phosphorylase (Brivudine) |
2 pi[c] + 2 Brivudine[c] + o2[c] -> 2 r1p[c] + 2 (E)-5-(2-Bromovinyl)Uracil[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 30733391 |
| DB11998 |
Sorivudine |
(E)-5-(2-Bromovinyl)Uracil |
Pdp |
Pyrimidine-Nucleoside Phosphorylase (Sorivudine) |
pi[c] + Sorivudine[c] -> r1p[c] + (E)-5-(2-Bromovinyl)Uracil[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 26261286, PMID: 9110360 |
| DB00682 |
R-6-Hydroxywarfarin_Glc |
R-6-Hydroxywarfarin |
UidAc |
R-6-Hydroxywarfarin Glucuronate beta-glucuronidase |
R-6-Hydroxywarfarin_glc[c] + h2o[c] -> R-6-Hydroxywarfarin[c] + glcur[c] + 2 h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00682 |
R-6-Hydroxywarfarin_Glc |
R-6-Hydroxywarfarin |
UidAe |
R-6-Hydroxywarfarin Glucuronate beta-glucuronidase extracellular |
R-6-Hydroxywarfarin_glc[e] + h2o[e] -> R-6-Hydroxywarfarin[e] + glcur[e] + 2 h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00682 |
R-6-Hydroxywarfarin_Glc |
R-6-Hydroxywarfarin |
UidAe |
R-6-Hydroxywarfarin Glucuronate beta-glucuronidase extracellular, periplasmatic |
R-6-Hydroxywarfarin_glc[p] + h2o[p] -> R-6-Hydroxywarfarin[p] + glcur[p] + 2 h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00682 |
R-6-Hydroxywarfarin_Glc |
R-6-Hydroxywarfarin_Glc |
UidABC |
Predicted glucuronide ABC transporter R-6-Hydroxywarfarin Glucuronate |
atp[c] + R-6-Hydroxywarfarin_glc[e] + h2o[c] -> adp[c] + R-6-Hydroxywarfarin_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
R-6-Hydroxywarfarin_Glc |
R-6-Hydroxywarfarin_Glc |
UidP |
Transport of D-Glucuronate R-6-Hydroxywarfarin Glucuronate |
R-6-Hydroxywarfarin_glc[e] -> R-6-Hydroxywarfarin_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
R-6-Hydroxywarfarin_Glc |
R-6-Hydroxywarfarin_Glc |
UidB |
Glucuronate transport in via proton symport R-6-Hydroxywarfarin Glucuronate |
R-6-Hydroxywarfarin_glc[e] + h[e] -> R-6-Hydroxywarfarin_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
R-6-Hydroxywarfarin_Glc |
R-6-Hydroxywarfarin_Glc |
UidB |
Glucuronate transport in via proton symport R-6-Hydroxywarfarin Glucuronate, periplasmatic |
R-6-Hydroxywarfarin_glc[p] + h[p] -> R-6-Hydroxywarfarin_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
R-6-Hydroxywarfarin_Glc |
R-6-Hydroxywarfarin_Glc |
n.a. |
R-6-Hydroxywarfarin Glucuronate diffusion extracellular to periplasm |
R-6-Hydroxywarfarin_glc[e] <=> R-6-Hydroxywarfarin_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
R-6-Hydroxywarfarin |
R-6-Hydroxywarfarin |
n.a. |
beta-glucuronidase reaction product export R-6-Hydroxywarfarin |
R-6-Hydroxywarfarin[c] -> R-6-Hydroxywarfarin[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
R-6-Hydroxywarfarin |
R-6-Hydroxywarfarin |
n.a. |
beta-glucuronidase reaction product export R-6-Hydroxywarfarin, periplasmatic |
R-6-Hydroxywarfarin[c] -> R-6-Hydroxywarfarin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
R-6-Hydroxywarfarin |
R-6-Hydroxywarfarin |
n.a. |
R-6-Hydroxywarfarin diffusion extracellular to periplasm |
R-6-Hydroxywarfarin[e] <=> R-6-Hydroxywarfarin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
R-7-Hydroxywarfarin_Glc |
R-7-Hydroxywarfarin |
UidAc |
R-7-Hydroxy Warfarin Glucuronate beta-glucuronidase |
R-7-Hydroxywarfarin_glc[c] + h2o[c] -> R-7-Hydroxywarfarin[c] + glcur[c] + 2 h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00682 |
R-7-Hydroxywarfarin_Glc |
R-7-Hydroxywarfarin |
UidAe |
R-7-Hydroxy Warfarin Glucuronate beta-glucuronidase extracellular |
R-7-Hydroxywarfarin_glc[e] + h2o[e] -> R-7-Hydroxywarfarin[e] + glcur[e] + 2 h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00682 |
R-7-Hydroxywarfarin_Glc |
R-7-Hydroxywarfarin |
UidAe |
R-7-Hydroxy Warfarin Glucuronate beta-glucuronidase extracellular, periplasmatic |
R-7-Hydroxywarfarin_glc[p] + h2o[p] -> R-7-Hydroxywarfarin[p] + glcur[p] + 2 h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00682 |
R-7-Hydroxywarfarin_Glc |
R-7-Hydroxywarfarin_Glc |
UidABC |
Predicted glucuronide ABC transporter R-7-Hydroxy Warfarin Glucuronate |
atp[c] + R-7-Hydroxywarfarin_glc[e] + h2o[c] -> adp[c] + R-7-Hydroxywarfarin_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
R-7-Hydroxywarfarin_Glc |
R-7-Hydroxywarfarin_Glc |
UidP |
Transport of D-Glucuronate R-7-Hydroxy Warfarin Glucuronate |
R-7-Hydroxywarfarin_glc[e] -> R-7-Hydroxywarfarin_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
R-7-Hydroxywarfarin_Glc |
R-7-Hydroxywarfarin_Glc |
UidB |
Glucuronate transport in via proton symport R-7-Hydroxy Warfarin Glucuronate |
R-7-Hydroxywarfarin_glc[e] + h[e] -> R-7-Hydroxywarfarin_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
R-7-Hydroxywarfarin_Glc |
R-7-Hydroxywarfarin_Glc |
UidB |
Glucuronate transport in via proton symport R-7-Hydroxy Warfarin Glucuronate, periplasmatic |
R-7-Hydroxywarfarin_glc[p] + h[p] -> R-7-Hydroxywarfarin_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
R-7-Hydroxywarfarin_Glc |
R-7-Hydroxywarfarin_Glc |
n.a. |
R-7-Hydroxy Warfarin Glucuronate diffusion extracellular to periplasm |
R-7-Hydroxywarfarin_glc[e] <=> R-7-Hydroxywarfarin_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
R-7-Hydroxywarfarin |
R-7-Hydroxywarfarin |
n.a. |
beta-glucuronidase reaction product export R-7-Hydroxywarfarin |
R-7-Hydroxywarfarin[c] -> R-7-Hydroxywarfarin[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
R-7-Hydroxywarfarin |
R-7-Hydroxywarfarin |
n.a. |
beta-glucuronidase reaction product export R-7-Hydroxywarfarin, periplasmatic |
R-7-Hydroxywarfarin[c] -> R-7-Hydroxywarfarin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
R-7-Hydroxywarfarin |
R-7-Hydroxywarfarin |
n.a. |
R-7-Hydroxywarfarin diffusion extracellular to periplasm |
R-7-Hydroxywarfarin[e] <=> R-7-Hydroxywarfarin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
R-8-Hydroxywarfarin_Glc |
R-8-Hydroxywarfarin |
UidAc |
R-8-Hydroxywarfarin Glucuronate beta-glucuronidase |
R-8-Hydroxywarfarin_glc[c] + h2o[c] -> R-8-Hydroxywarfarin[c] + glcur[c] + 2 h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00682 |
R-8-Hydroxywarfarin_Glc |
R-8-Hydroxywarfarin |
UidAe |
R-8-Hydroxywarfarin Glucuronate beta-glucuronidase extracellular |
R-8-Hydroxywarfarin_glc[e] + h2o[e] -> R-8-Hydroxywarfarin[e] + glcur[e] + 2 h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00682 |
R-8-Hydroxywarfarin_Glc |
R-8-Hydroxywarfarin |
UidAe |
R-8-Hydroxywarfarin Glucuronate beta-glucuronidase extracellular, periplasmatic |
R-8-Hydroxywarfarin_glc[p] + h2o[p] -> R-8-Hydroxywarfarin[p] + glcur[p] + 2 h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00682 |
R-8-Hydroxywarfarin_Glc |
R-8-Hydroxywarfarin_Glc |
UidABC |
Predicted glucuronide ABC transporter R-8-Hydroxywarfarin Glucuronate |
atp[c] + R-8-Hydroxywarfarin_glc[e] + h2o[c] -> adp[c] + R-8-Hydroxywarfarin_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
R-8-Hydroxywarfarin_Glc |
R-8-Hydroxywarfarin_Glc |
UidP |
Transport of D-Glucuronate R-8-Hydroxywarfarin Glucuronate |
R-8-Hydroxywarfarin_glc[e] -> R-8-Hydroxywarfarin_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
R-8-Hydroxywarfarin_Glc |
R-8-Hydroxywarfarin_Glc |
UidB |
Glucuronate transport in via proton symport R-8-Hydroxywarfarin Glucuronate |
R-8-Hydroxywarfarin_glc[e] + h[e] -> R-8-Hydroxywarfarin_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
R-8-Hydroxywarfarin_Glc |
R-8-Hydroxywarfarin_Glc |
UidB |
Glucuronate transport in via proton symport R-8-Hydroxywarfarin Glucuronate, periplasmatic |
R-8-Hydroxywarfarin_glc[p] + h[p] -> R-8-Hydroxywarfarin_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
R-8-Hydroxywarfarin_Glc |
R-8-Hydroxywarfarin_Glc |
n.a. |
R-8-Hydroxywarfarin Glucuronate diffusion extracellular to periplasm |
R-8-Hydroxywarfarin_glc[e] <=> R-8-Hydroxywarfarin_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
R-8-Hydroxywarfarin |
R-8-Hydroxywarfarin |
n.a. |
beta-glucuronidase reaction product export R-8-Hydroxywarfarin |
R-8-Hydroxywarfarin[c] -> R-8-Hydroxywarfarin[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
R-8-Hydroxywarfarin |
R-8-Hydroxywarfarin |
n.a. |
beta-glucuronidase reaction product export R-8-Hydroxywarfarin, periplasmatic |
R-8-Hydroxywarfarin[c] -> R-8-Hydroxywarfarin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
R-8-Hydroxywarfarin |
R-8-Hydroxywarfarin |
n.a. |
R-8-Hydroxywarfarin diffusion extracellular to periplasm |
R-8-Hydroxywarfarin[e] <=> R-8-Hydroxywarfarin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB07159 |
R406_Glc |
R406 |
UidAc |
Lactam N-Glucuronide Of R406 beta-glucuronidase |
R406_glc[c] + h2o[c] -> R406[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 20371637 |
| DB07159 |
R406_Glc |
R406 |
UidAe |
Lactam N-Glucuronide Of R406 beta-glucuronidase extracellular |
R406_glc[e] + h2o[e] -> R406[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 20371637 |
| DB07159 |
R406_Glc |
R406 |
UidAe |
Lactam N-Glucuronide Of R406 beta-glucuronidase extracellular, periplasmatic |
h2o[p] + R406_glc[p] -> glcur[p] + h[p] + R406[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB07159 |
R406_Glc |
R406_Glc |
UidABC |
Predicted glucuronide ABC transporter Lactam N-Glucuronide Of R406 |
atp[c] + R406_glc[e] + h2o[c] -> adp[c] + R406_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 20371637 |
| DB07159 |
R406_Glc |
R406_Glc |
UidP |
Transport of D-Glucuronate Lactam N-Glucuronide Of R406 |
R406_glc[e] -> R406_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB07159 |
R406_Glc |
R406_Glc |
UidB |
Glucuronate transport in via proton symport Lactam N-Glucuronide Of R406 |
R406_glc[e] + h[e] -> R406_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB07159 |
R406_Glc |
R406_Glc |
UidB |
Glucuronate transport in via proton symport Lactam N-Glucuronide Of R406, periplasmatic |
h[p] + R406_glc[p] -> h[c] + R406_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB07159 |
R406_Glc |
R406_Glc |
n.a. |
Lactam N-Glucuronide Of R406 diffusion extracellular to periplasm |
R406_glc[e] <=> R406_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB07159 |
R406 |
R406 |
n.a. |
beta-glucuronidase reaction product export R406 |
R406[c] -> R406[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB07159 |
R406 |
R406 |
n.a. |
beta-glucuronidase reaction product export R406, periplasmatic |
R406[c] -> R406[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB07159 |
R406 |
R406 |
n.a. |
R406 diffusion extracellular to periplasm |
R406[e] <=> R406[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
R529_Glc |
R529 |
UidAc |
Glucuronide R529 beta-glucuronidase |
R529_glc[c] + h2o[c] -> R529[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 20371637 |
| n.a. |
R529_Glc |
R529 |
UidAe |
Glucuronide R529 beta-glucuronidase extracellular |
R529_glc[e] + h2o[e] -> R529[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 20371637 |
| n.a. |
R529_Glc |
R529 |
UidAe |
Glucuronide R529 beta-glucuronidase extracellular, periplasmatic |
h2o[p] + R529_glc[p] -> glcur[p] + h[p] + R529[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
R529_Glc |
R529_Glc |
UidABC |
Predicted glucuronide ABC transporter Glucuronide R529 |
atp[c] + R529_glc[e] + h2o[c] -> adp[c] + R529_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 20371637 |
| n.a. |
R529_Glc |
R529_Glc |
UidP |
Transport of D-Glucuronate Glucuronide R529 |
R529_glc[e] -> R529_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
R529_Glc |
R529_Glc |
UidB |
Glucuronate transport in via proton symport Glucuronide R529 |
R529_glc[e] + h[e] -> R529_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
R529_Glc |
R529_Glc |
UidB |
Glucuronate transport in via proton symport Glucuronide R529, periplasmatic |
h[p] + R529_glc[p] -> h[c] + R529_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
R529_Glc |
R529_Glc |
n.a. |
Glucuronide R529 diffusion extracellular to periplasm |
R529_glc[e] <=> R529_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
R529 |
R529 |
n.a. |
beta-glucuronidase reaction product export R529 |
R529[c] -> R529[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
R529 |
R529 |
n.a. |
beta-glucuronidase reaction product export R529, periplasmatic |
R529[c] -> R529[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
R529 |
R529 |
n.a. |
R529 diffusion extracellular to periplasm |
R529[e] <=> R529[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB12010 |
R788 (Fostamatinib) |
R788 (Fostamatinib) |
n.a. |
R788 (Fostamatinib) transport in via proton symport |
h[e] + R788 (Fostamatinib)[e] -> h[c] + R788 (Fostamatinib)[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB12010 |
R788 (Fostamatinib) |
R788 (Fostamatinib) |
n.a. |
R788 (Fostamatinib) transport in via proton symport, periplasmatic |
h[p] + R788 (Fostamatinib)[p] -> h[c] + R788 (Fostamatinib)[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB12010 |
R788 (Fostamatinib) |
R788 (Fostamatinib) |
n.a. |
R788 (Fostamatinib) diffusion extracellular to periplasm |
R788 (Fostamatinib)[e] <=> R788 (Fostamatinib)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB08896 |
Regorafenib_Glc |
Regorafenib |
UidAc |
Regorafenib-glucuronide beta-glucuronidase |
Regorafenib_glc[c] + h2o[c] -> Regorafenib[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 31663730 |
| DB08896 |
Regorafenib_Glc |
Regorafenib |
UidAe |
Regorafenib-glucuronide beta-glucuronidase extracellular |
Regorafenib_glc[e] + h2o[e] -> Regorafenib[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 31663730 |
| DB08896 |
Regorafenib_Glc |
Regorafenib |
UidAe |
Regorafenib-glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Regorafenib_glc[p] -> glcur[p] + h[p] + Regorafenib[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB08896 |
Regorafenib_Glc |
Regorafenib_Glc |
UidABC |
Predicted glucuronide ABC transporter regorafenib-glucuronide |
atp[c] + Regorafenib_glc[e] + h2o[c] -> adp[c] + Regorafenib_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB08896 |
Regorafenib_Glc |
Regorafenib_Glc |
UidP |
Transport of regorafenib-glucuronide |
Regorafenib_glc[e] -> Regorafenib_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB08896 |
Regorafenib_Glc |
Regorafenib_Glc |
UidB |
Glucuronate transport in via proton symport regorafenib-glucuronide |
Regorafenib_glc[e] + h[e] -> Regorafenib_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB08896 |
Regorafenib_Glc |
Regorafenib_Glc |
UidB |
Glucuronate transport in via proton symport regorafenib-glucuronide, periplasmatic |
h[p] + Regorafenib_glc[p] -> h[c] + Regorafenib_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB08896 |
Regorafenib_Glc |
Regorafenib_Glc |
n.a. |
regorafenib-N-???-glucuronide diffusion extracellular to periplasm |
Regorafenib_glc[e] <=> Regorafenib_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB08896 |
Regorafenib |
Regorafenib |
n.a. |
beta-glucuronidase reaction product export regorafenib |
Regorafenib[c] -> Regorafenib[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB08896 |
Regorafenib |
Regorafenib |
n.a. |
beta-glucuronidase reaction product export regorafenib, periplasmatic |
Regorafenib[c] -> Regorafenib[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB08896 |
Regorafenib |
Regorafenib |
n.a. |
Regorafenib diffusion extracellular to periplasm |
Regorafenib[e] <=> Regorafenib[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00912 |
Repaglinide_Glc |
Repaglinide |
UidAc |
Repaglinide Acyl-Beta-D-Glucuronide beta-glucuronidase |
Repaglinide_glc[c] + h2o[c] -> Repaglinide[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00912 |
Repaglinide_Glc |
Repaglinide |
UidAe |
Repaglinide Acyl-Beta-D-Glucuronide beta-glucuronidase extracellular |
Repaglinide_glc[e] + h2o[e] -> Repaglinide[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00912 |
Repaglinide_Glc |
Repaglinide |
UidAe |
Repaglinide Acyl-Beta-D-Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Repaglinide_glc[p] -> glcur[p] + h[p] + Repaglinide[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00912 |
Repaglinide_Glc |
Repaglinide_Glc |
UidABC |
Predicted glucuronide ABC transporter Repaglinide Acyl-Beta-D-Glucuronide |
atp[c] + Repaglinide_glc[e] + h2o[c] -> adp[c] + Repaglinide_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00912 |
Repaglinide_Glc |
Repaglinide_Glc |
UidP |
Transport of D-Glucuronate Repaglinide Acyl-Beta-D-Glucuronide |
Repaglinide_glc[e] -> Repaglinide_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00912 |
Repaglinide_Glc |
Repaglinide_Glc |
UidB |
Glucuronate transport in via proton symport Repaglinide Acyl-Beta-D-Glucuronide |
Repaglinide_glc[e] + h[e] -> Repaglinide_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00912 |
Repaglinide_Glc |
Repaglinide_Glc |
UidB |
Glucuronate transport in via proton symport Repaglinide Acyl-Beta-D-Glucuronide, periplasmatic |
h[p] + Repaglinide_glc[p] -> h[c] + Repaglinide_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00912 |
Repaglinide_Glc |
Repaglinide_Glc |
n.a. |
Repaglinide Acyl-Beta-D-Glucuronide diffusion extracellular to periplasm |
Repaglinide_glc[e] <=> Repaglinide_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00912 |
Repaglinide |
Repaglinide |
n.a. |
beta-glucuronidase reaction product export Repaglinide |
Repaglinide[c] -> Repaglinide[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00912 |
Repaglinide |
Repaglinide |
n.a. |
beta-glucuronidase reaction product export Repaglinide, periplasmatic |
Repaglinide[c] -> Repaglinide[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00912 |
Repaglinide |
Repaglinide |
n.a. |
Repaglinide diffusion extracellular to periplasm |
Repaglinide[e] <=> Repaglinide[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Skf 104557 (N-Despropyl Ropinirole)_Cb_Glc |
Skf 104557 (N-Despropyl Ropinirole) |
UidAc |
SKF 104557 Carbamyl Glucuronide beta-glucuronidase |
SKF 104557 (N-Despropyl Ropinirole)_cb_glc[c] + h2o[c] -> SKF 104557 (N-Despropyl Ropinirole)[c] + glcur[c] + co2[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Skf 104557 (N-Despropyl Ropinirole)_Cb_Glc |
Skf 104557 (N-Despropyl Ropinirole) |
UidAe |
SKF 104557 Carbamyl Glucuronide beta-glucuronidase extracellular |
SKF 104557 (N-Despropyl Ropinirole)_cb_glc[e] + h2o[e] -> SKF 104557 (N-Despropyl Ropinirole)[e] + glcur[e] + co2[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Skf 104557 (N-Despropyl Ropinirole)_Cb_Glc |
Skf 104557 (N-Despropyl Ropinirole) |
UidAe |
SKF 104557 Carbamyl Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + SKF 104557 (N-Despropyl Ropinirole)_cb_glc[p] -> co2[p] + glcur[p] + h[p] + SKF 104557 (N-Despropyl Ropinirole)[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Skf 104557 (N-Despropyl Ropinirole)_Cb_Glc |
Skf 104557 (N-Despropyl Ropinirole)_Cb_Glc |
UidABC |
Predicted glucuronide ABC transporter SKF 104557 Carbamyl Glucuronide |
atp[c] + SKF 104557 (N-Despropyl Ropinirole)_cb_glc[e] + h2o[c] -> adp[c] + SKF 104557 (N-Despropyl Ropinirole)_cb_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Skf 104557 (N-Despropyl Ropinirole)_Cb_Glc |
Skf 104557 (N-Despropyl Ropinirole)_Cb_Glc |
UidP |
Transport of D-Glucuronate SKF 104557 Carbamyl Glucuronide |
SKF 104557 (N-Despropyl Ropinirole)_cb_glc[e] -> SKF 104557 (N-Despropyl Ropinirole)_cb_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Skf 104557 (N-Despropyl Ropinirole)_Cb_Glc |
Skf 104557 (N-Despropyl Ropinirole)_Cb_Glc |
UidB |
Glucuronate transport in via proton symport SKF 104557 Carbamyl Glucuronide |
SKF 104557 (N-Despropyl Ropinirole)_cb_glc[e] + h[e] -> SKF 104557 (N-Despropyl Ropinirole)_cb_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Skf 104557 (N-Despropyl Ropinirole)_Cb_Glc |
Skf 104557 (N-Despropyl Ropinirole)_Cb_Glc |
UidB |
Glucuronate transport in via proton symport SKF 104557 Carbamyl Glucuronide, periplasmatic |
h[p] + SKF 104557 (N-Despropyl Ropinirole)_cb_glc[p] -> h[c] + SKF 104557 (N-Despropyl Ropinirole)_cb_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Skf 104557 (N-Despropyl Ropinirole)_Cb_Glc |
Skf 104557 (N-Despropyl Ropinirole)_Cb_Glc |
n.a. |
SKF 104557 Carbamyl Glucuronide diffusion extracellular to periplasm |
SKF 104557 (N-Despropyl Ropinirole)_cb_glc[e] <=> SKF 104557 (N-Despropyl Ropinirole)_cb_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Skf 104557 (N-Despropyl Ropinirole) |
Skf 104557 (N-Despropyl Ropinirole) |
n.a. |
beta-glucuronidase reaction product export SKF 104557 (N-Despropyl Ropinirole) |
SKF 104557 (N-Despropyl Ropinirole)[c] -> SKF 104557 (N-Despropyl Ropinirole)[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Skf 104557 (N-Despropyl Ropinirole) |
Skf 104557 (N-Despropyl Ropinirole) |
n.a. |
beta-glucuronidase reaction product export SKF 104557 (N-Despropyl Ropinirole), periplasmatic |
SKF 104557 (N-Despropyl Ropinirole)[c] -> SKF 104557 (N-Despropyl Ropinirole)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Skf 104557 (N-Despropyl Ropinirole) |
Skf 104557 (N-Despropyl Ropinirole) |
n.a. |
SKF 104557 (N-Despropyl Ropinirole) diffusion extracellular to periplasm |
SKF 104557 (N-Despropyl Ropinirole)[e] <=> SKF 104557 (N-Despropyl Ropinirole)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Skf 96990_Glc |
Skf 96990 |
UidAc |
SKF 96990 Glucuronide beta-glucuronidase |
SKF 96990_glc[c] + h2o[c] -> SKF 96990[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Skf 96990_Glc |
Skf 96990 |
UidAe |
SKF 96990 Glucuronide beta-glucuronidase extracellular |
SKF 96990_glc[e] + h2o[e] -> SKF 96990[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Skf 96990_Glc |
Skf 96990 |
UidAe |
SKF 96990 Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + SKF 96990_glc[p] -> glcur[p] + SKF 96990[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Skf 96990_Glc |
Skf 96990_Glc |
UidABC |
Predicted glucuronide ABC transporter SKF 96990 Glucuronide |
atp[c] + SKF 96990_glc[e] + h2o[c] -> adp[c] + SKF 96990_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Skf 96990_Glc |
Skf 96990_Glc |
UidP |
Transport of D-Glucuronate SKF 96990 Glucuronide |
SKF 96990_glc[e] -> SKF 96990_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Skf 96990_Glc |
Skf 96990_Glc |
UidB |
Glucuronate transport in via proton symport SKF 96990 Glucuronide |
SKF 96990_glc[e] + h[e] -> SKF 96990_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Skf 96990_Glc |
Skf 96990_Glc |
UidB |
Glucuronate transport in via proton symport SKF 96990 Glucuronide, periplasmatic |
h[p] + SKF 96990_glc[p] -> h[c] + SKF 96990_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Skf 96990_Glc |
Skf 96990_Glc |
n.a. |
SKF 96990 Glucuronide diffusion extracellular to periplasm |
SKF 96990_glc[e] <=> SKF 96990_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Skf 96990 |
Skf 96990 |
n.a. |
beta-glucuronidase reaction product export SKF 96990 |
SKF 96990[c] -> SKF 96990[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Skf 96990 |
Skf 96990 |
n.a. |
beta-glucuronidase reaction product export SKF 96990, periplasmatic |
SKF 96990[c] -> SKF 96990[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Skf 96990 |
Skf 96990 |
n.a. |
SKF 96990 diffusion extracellular to periplasm |
SKF 96990[e] <=> SKF 96990[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00268 |
Hydroxy Ropinirole_Glc |
Hydroxy Ropinirole |
UidAc |
SKF 89124 Glucuronide beta-glucuronidase |
Hydroxy Ropinirole_glc[c] + h2o[c] -> Hydroxy Ropinirole[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00268 |
Hydroxy Ropinirole_Glc |
Hydroxy Ropinirole |
UidAe |
SKF 89124 Glucuronide beta-glucuronidase extracellular |
Hydroxy Ropinirole_glc[e] + h2o[e] -> Hydroxy Ropinirole[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00268 |
Hydroxy Ropinirole_Glc |
Hydroxy Ropinirole |
UidAe |
SKF 89124 Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Hydroxy Ropinirole_glc[p] -> glcur[p] + Hydroxy Ropinirole[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00268 |
Hydroxy Ropinirole_Glc |
Hydroxy Ropinirole_Glc |
UidABC |
Predicted glucuronide ABC transporter SKF 89124 Glucuronide |
atp[c] + Hydroxy Ropinirole_glc[e] + h2o[c] -> adp[c] + Hydroxy Ropinirole_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00268 |
Hydroxy Ropinirole_Glc |
Hydroxy Ropinirole_Glc |
UidP |
Transport of D-Glucuronate SKF 89124 Glucuronide |
Hydroxy Ropinirole_glc[e] -> Hydroxy Ropinirole_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00268 |
Hydroxy Ropinirole_Glc |
Hydroxy Ropinirole_Glc |
UidB |
Glucuronate transport in via proton symport SKF 89124 Glucuronide |
Hydroxy Ropinirole_glc[e] + h[e] -> Hydroxy Ropinirole_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00268 |
Hydroxy Ropinirole_Glc |
Hydroxy Ropinirole_Glc |
UidB |
Glucuronate transport in via proton symport SKF 89124 Glucuronide, periplasmatic |
h[p] + Hydroxy Ropinirole_glc[p] -> h[c] + Hydroxy Ropinirole_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00268 |
Hydroxy Ropinirole_Glc |
Hydroxy Ropinirole_Glc |
n.a. |
SKF 89124 Glucuronide diffusion extracellular to periplasm |
Hydroxy Ropinirole_glc[e] <=> Hydroxy Ropinirole_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00268 |
Hydroxy Ropinirole |
Hydroxy Ropinirole |
n.a. |
beta-glucuronidase reaction product export Hydroxy Ropinirole |
Hydroxy Ropinirole[c] -> Hydroxy Ropinirole[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00268 |
Hydroxy Ropinirole |
Hydroxy Ropinirole |
n.a. |
beta-glucuronidase reaction product export Hydroxy Ropinirole, periplasmatic |
Hydroxy Ropinirole[c] -> Hydroxy Ropinirole[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00268 |
Hydroxy Ropinirole |
Hydroxy Ropinirole |
n.a. |
Hydroxy Ropinirole diffusion extracellular to periplasm |
Hydroxy Ropinirole[e] <=> Hydroxy Ropinirole[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01098 |
Rosuvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
Rosuvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
UidAc |
rosuvastatin-glucuronide beta-glucuronidase |
rosuvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[c] + 2 h2o[c] -> rosuvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[c] + 2 glcur[c] + 2 h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01098 |
Rosuvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
Rosuvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
UidAe |
rosuvastatin-glucuronide beta-glucuronidase extracellular |
rosuvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[e] + 2 h2o[e] -> rosuvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[e] + 2 glcur[e] + 2 h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01098 |
Rosuvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
Rosuvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
UidAe |
rosuvastatin-glucuronide beta-glucuronidase extracellular, periplasmatic |
2 h2o[p] + rosuvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[p] -> 2 glcur[p] + 2 h[p] + rosuvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01098 |
Rosuvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
Rosuvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
UidABC |
Predicted glucuronide ABC transporter rosuvastatin-glucuronide |
atp[c] + rosuvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[e] + h2o[c] -> adp[c] + rosuvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01098 |
Rosuvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
Rosuvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
UidP |
Transport of D-Glucuronate rosuvastatin-glucuronide |
rosuvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[e] -> rosuvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01098 |
Rosuvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
Rosuvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
UidB |
Glucuronate transport in via proton symport rosuvastatin-glucuronide |
rosuvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[e] + h[e] -> rosuvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01098 |
Rosuvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
Rosuvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
UidB |
Glucuronate transport in via proton symport rosuvastatin-glucuronide, periplasmatic |
h[p] + rosuvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[p] -> h[c] + rosuvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01098 |
Rosuvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
Rosuvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc |
n.a. |
rosuvastatin-glucuronide diffusion extracellular to periplasm |
rosuvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[e] <=> rosuvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidingluc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01098 |
Rosuvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
Rosuvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
n.a. |
beta-glucuronidase reaction product export rosuvastatin |
rosuvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[c] -> rosuvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01098 |
Rosuvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
Rosuvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
n.a. |
beta-glucuronidase reaction product export rosuvastatin, periplasmatic |
rosuvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[c] -> rosuvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01098 |
Rosuvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
Rosuvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin |
n.a. |
rosuvastatin diffusion extracellular to periplasm |
rosuvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[e] <=> rosuvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
S-4-Hydroxywarfarin_Glc |
S-4-Hydroxywarfarin |
UidAc |
S-4-Hydroxywarfarin Glucuronate beta-glucuronidase |
S-4-Hydroxywarfarin_glc[c] + h2o[c] -> S-4-Hydroxywarfarin[c] + glcur[c] + 2 h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00682 |
S-4-Hydroxywarfarin_Glc |
S-4-Hydroxywarfarin |
UidAe |
S-4-Hydroxywarfarin Glucuronate beta-glucuronidase extracellular |
S-4-Hydroxywarfarin_glc[e] + h2o[e] -> S-4-Hydroxywarfarin[e] + glcur[e] + 2 h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00682 |
S-4-Hydroxywarfarin_Glc |
S-4-Hydroxywarfarin |
UidAe |
S-4-Hydroxywarfarin Glucuronate beta-glucuronidase extracellular, periplasmatic |
S-4-Hydroxywarfarin_glc[p] + h2o[p] -> S-4-Hydroxywarfarin[p] + glcur[p] + 2 h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00682 |
S-4-Hydroxywarfarin_Glc |
S-4-Hydroxywarfarin_Glc |
UidABC |
Predicted glucuronide ABC transporter S-4-Hydroxywarfarin Glucuronate |
atp[c] + S-4-Hydroxywarfarin_glc[e] + h2o[c] -> adp[c] + S-4-Hydroxywarfarin_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
S-4-Hydroxywarfarin_Glc |
S-4-Hydroxywarfarin_Glc |
UidP |
Transport of D-Glucuronate S-4-Hydroxywarfarin Glucuronate |
S-4-Hydroxywarfarin_glc[e] -> S-4-Hydroxywarfarin_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
S-4-Hydroxywarfarin_Glc |
S-4-Hydroxywarfarin_Glc |
UidB |
Glucuronate transport in via proton symport S-4-Hydroxywarfarin Glucuronate |
S-4-Hydroxywarfarin_glc[e] + h[e] -> S-4-Hydroxywarfarin_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
S-4-Hydroxywarfarin_Glc |
S-4-Hydroxywarfarin_Glc |
UidB |
Glucuronate transport in via proton symport S-4-Hydroxywarfarin Glucuronate, periplasmatic |
S-4-Hydroxywarfarin_glc[p] + h[p] -> S-4-Hydroxywarfarin_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
S-4-Hydroxywarfarin_Glc |
S-4-Hydroxywarfarin_Glc |
n.a. |
S-4-Hydroxywarfarin Glucuronate diffusion extracellular to periplasm |
S-4-Hydroxywarfarin_glc[e] <=> S-4-Hydroxywarfarin_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
S-4-Hydroxywarfarin |
S-4-Hydroxywarfarin |
n.a. |
beta-glucuronidase reaction product export S-4-Hydroxywarfarin |
S-4-Hydroxywarfarin[c] -> S-4-Hydroxywarfarin[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
S-4-Hydroxywarfarin |
S-4-Hydroxywarfarin |
n.a. |
beta-glucuronidase reaction product export S-4-Hydroxywarfarin, periplasmatic |
S-4-Hydroxywarfarin[c] -> S-4-Hydroxywarfarin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
S-4-Hydroxywarfarin |
S-4-Hydroxywarfarin |
n.a. |
S-4-Hydroxywarfarin diffusion extracellular to periplasm |
S-4-Hydroxywarfarin[e] <=> S-4-Hydroxywarfarin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
S-6-Hydroxywarfarin_Glc |
S-6-Hydroxywarfarin |
UidAc |
S-6-Hydroxywarfarin Glucuronate beta-glucuronidase |
S-6-Hydroxywarfarin_glc[c] + h2o[c] -> S-6-Hydroxywarfarin[c] + glcur[c] + 2 h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00682 |
S-6-Hydroxywarfarin_Glc |
S-6-Hydroxywarfarin |
UidAe |
S-6-Hydroxywarfarin Glucuronate beta-glucuronidase extracellular |
S-6-Hydroxywarfarin_glc[e] + h2o[e] -> S-6-Hydroxywarfarin[e] + glcur[e] + 2 h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00682 |
S-6-Hydroxywarfarin_Glc |
S-6-Hydroxywarfarin |
UidAe |
S-6-Hydroxywarfarin Glucuronate beta-glucuronidase extracellular, periplasmatic |
S-6-Hydroxywarfarin_glc[p] + h2o[p] -> S-6-Hydroxywarfarin[p] + glcur[p] + 2 h[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00682 |
S-6-Hydroxywarfarin_Glc |
S-6-Hydroxywarfarin_Glc |
UidABC |
Predicted glucuronide ABC transporter S-6-Hydroxywarfarin Glucuronate |
atp[c] + S-6-Hydroxywarfarin_glc[e] + h2o[c] -> adp[c] + S-6-Hydroxywarfarin_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
S-6-Hydroxywarfarin_Glc |
S-6-Hydroxywarfarin_Glc |
UidP |
Transport of D-Glucuronate S-6-Hydroxywarfarin Glucuronate |
S-6-Hydroxywarfarin_glc[e] -> S-6-Hydroxywarfarin_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
S-6-Hydroxywarfarin_Glc |
S-6-Hydroxywarfarin_Glc |
UidB |
Glucuronate transport in via proton symport S-6-Hydroxywarfarin Glucuronate |
S-6-Hydroxywarfarin_glc[e] + h[e] -> S-6-Hydroxywarfarin_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
S-6-Hydroxywarfarin_Glc |
S-6-Hydroxywarfarin_Glc |
UidB |
Glucuronate transport in via proton symport S-6-Hydroxywarfarin Glucuronate, periplasmatic |
S-6-Hydroxywarfarin_glc[p] + h[p] -> S-6-Hydroxywarfarin_glc[c] + h[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
S-6-Hydroxywarfarin_Glc |
S-6-Hydroxywarfarin_Glc |
n.a. |
S-6-Hydroxywarfarin Glucuronate diffusion extracellular to periplasm |
S-6-Hydroxywarfarin_glc[e] <=> S-6-Hydroxywarfarin_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
S-6-Hydroxywarfarin |
S-6-Hydroxywarfarin |
n.a. |
beta-glucuronidase reaction product export S-6-Hydroxywarfarin |
S-6-Hydroxywarfarin[c] -> S-6-Hydroxywarfarin[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
S-6-Hydroxywarfarin |
S-6-Hydroxywarfarin |
n.a. |
beta-glucuronidase reaction product export S-6-Hydroxywarfarin, periplasmatic |
S-6-Hydroxywarfarin[c] -> S-6-Hydroxywarfarin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00682 |
S-6-Hydroxywarfarin |
S-6-Hydroxywarfarin |
n.a. |
S-6-Hydroxywarfarin diffusion extracellular to periplasm |
S-6-Hydroxywarfarin[e] <=> S-6-Hydroxywarfarin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00259 |
Sulfanilamide |
Sulfanilamide |
AzorDMT |
Sulfanilamide transport via proton symport |
Sulfanilamide[e] + h[e] <=> Sulfanilamide[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00259 |
Sulfanilamide |
Sulfanilamide |
AzorDMT |
Sulfanilamide transport via proton symport, periplasmatic |
h[p] + Sulfanilamide[p] <=> h[c] + Sulfanilamide[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00259 |
Sulfanilamide |
Sulfanilamide |
n.a. |
Sulfanilamide diffusion extracellular to periplasm |
Sulfanilamide[e] <=> Sulfanilamide[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Sb-611855 (Intermediate Of M3) |
Sb-611855 (Intermediate Of M3) |
n.a. |
beta-glucuronidase reaction product export Sb-611855 (Intermediate Of M3) |
Sb-611855 (Intermediate Of M3)[c] -> Sb-611855 (Intermediate Of M3)[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Sb-611855 (Intermediate Of M3) |
Sb-611855 (Intermediate Of M3) |
n.a. |
beta-glucuronidase reaction product export Sb-611855 (Intermediate Of M3), periplasmatic |
Sb-611855 (Intermediate Of M3)[c] -> Sb-611855 (Intermediate Of M3)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Sb-611855 (Intermediate Of M3) |
Sb-611855 (Intermediate Of M3) |
n.a. |
Sb-611855 (Intermediate Of M3) diffusion extracellular to periplasm |
Sb-611855 (Intermediate Of M3)[e] <=> Sb-611855 (Intermediate Of M3)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Sb_Y (Intermediate Of M4) |
Sb_Y (Intermediate Of M4) |
n.a. |
beta-glucuronidase reaction product export Sb_Y (Intermediate Of M4) |
Sb_Y (Intermediate Of M4)[c] -> Sb_Y (Intermediate Of M4)[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Sb_Y (Intermediate Of M4) |
Sb_Y (Intermediate Of M4) |
n.a. |
beta-glucuronidase reaction product export Sb_Y (Intermediate Of M4), periplasmatic |
Sb_Y (Intermediate Of M4)[c] -> Sb_Y (Intermediate Of M4)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Sb_Y (Intermediate Of M4) |
Sb_Y (Intermediate Of M4) |
n.a. |
Sb_Y (Intermediate Of M4) diffusion extracellular to periplasm |
Sb_Y (Intermediate Of M4)[e] <=> Sb_Y (Intermediate Of M4)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Sch 488128 |
Ezetimibe |
UidAc |
SCH 488128 beta-glucuronidase |
SCH 488128[c] + h2o[c] -> Ezetimibe[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Sch 488128 |
Ezetimibe |
UidAe |
SCH 488128 beta-glucuronidase extracellular |
SCH 488128[e] + h2o[e] -> Ezetimibe[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Sch 488128 |
Ezetimibe |
UidAe |
SCH 488128 beta-glucuronidase extracellular, periplasmatic |
h2o[p] + SCH 488128[p] -> Ezetimibe[p] + glcur[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Sch 488128 |
Sch 488128 |
UidABC |
Predicted glucuronide ABC transporter SCH 488128 |
atp[c] + SCH 488128[e] + h2o[c] -> adp[c] + SCH 488128[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Sch 488128 |
Sch 488128 |
UidP |
Transport of D-Glucuronate SCH 488128 |
SCH 488128[e] -> SCH 488128[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Sch 488128 |
Sch 488128 |
UidB |
Glucuronate transport in via proton symport SCH 488128 |
SCH 488128[e] + h[e] -> SCH 488128[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Sch 488128 |
Sch 488128 |
UidB |
Glucuronate transport in via proton symport SCH 488128, periplasmatic |
h[p] + SCH 488128[p] -> h[c] + SCH 488128[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Sch 488128 |
Sch 488128 |
n.a. |
SCH 488128 diffusion extracellular to periplasm |
SCH 488128[e] <=> SCH 488128[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Sch 57871_Glc |
Sch 57871 |
UidAc |
SCH 57871 Glucuronide beta-glucuronidase |
SCH 57871_glc[c] + h2o[c] -> SCH 57871[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Sch 57871_Glc |
Sch 57871 |
UidAe |
SCH 57871 Glucuronide beta-glucuronidase extracellular |
SCH 57871_glc[e] + h2o[e] -> SCH 57871[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Sch 57871_Glc |
Sch 57871 |
UidAe |
SCH 57871 Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + SCH 57871_glc[p] -> glcur[p] + SCH 57871[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
Sch 57871_Glc |
Sch 57871_Glc |
UidABC |
Predicted glucuronide ABC transporter SCH 57871 Glucuronide |
atp[c] + SCH 57871_glc[e] + h2o[c] -> adp[c] + SCH 57871_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Sch 57871_Glc |
Sch 57871_Glc |
UidP |
Transport of D-Glucuronate SCH 57871 Glucuronide |
SCH 57871_glc[e] -> SCH 57871_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Sch 57871_Glc |
Sch 57871_Glc |
UidB |
Glucuronate transport in via proton symport SCH 57871 Glucuronide |
SCH 57871_glc[e] + h[e] -> SCH 57871_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Sch 57871_Glc |
Sch 57871_Glc |
UidB |
Glucuronate transport in via proton symport SCH 57871 Glucuronide, periplasmatic |
h[p] + SCH 57871_glc[p] -> h[c] + SCH 57871_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Sch 57871_Glc |
Sch 57871_Glc |
n.a. |
SCH 57871 Glucuronide diffusion extracellular to periplasm |
SCH 57871_glc[e] <=> SCH 57871_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Sch 57871 |
Sch 57871 |
n.a. |
beta-glucuronidase reaction product export SCH 57871 |
SCH 57871[c] -> SCH 57871[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Sch 57871 |
Sch 57871 |
n.a. |
beta-glucuronidase reaction product export SCH 57871, periplasmatic |
SCH 57871[c] -> SCH 57871[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Sch 57871 |
Sch 57871 |
n.a. |
SCH 57871 diffusion extracellular to periplasm |
SCH 57871[e] <=> SCH 57871[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB06654 |
Nw 1689 (N-Dealkylated Safinamide)_Glc |
Nw 1689 (N-Dealkylated Safinamide) |
UidAc |
Nw 1689 Acyl Glucuronide beta-glucuronidase |
Nw 1689 (N-Dealkylated Safinamide)_glc[c] + h2o[c] -> Nw 1689 (N-Dealkylated Safinamide)[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB06654 |
Nw 1689 (N-Dealkylated Safinamide)_Glc |
Nw 1689 (N-Dealkylated Safinamide) |
UidAe |
Nw 1689 Acyl Glucuronide beta-glucuronidase extracellular |
Nw 1689 (N-Dealkylated Safinamide)_glc[e] + h2o[e] -> Nw 1689 (N-Dealkylated Safinamide)[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB06654 |
Nw 1689 (N-Dealkylated Safinamide)_Glc |
Nw 1689 (N-Dealkylated Safinamide) |
UidAe |
Nw 1689 Acyl Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Nw 1689 (N-Dealkylated Safinamide)_glc[p] -> glcur[p] + h[p] + Nw 1689 (N-Dealkylated Safinamide)[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB06654 |
Nw 1689 (N-Dealkylated Safinamide)_Glc |
Nw 1689 (N-Dealkylated Safinamide)_Glc |
UidABC |
Predicted glucuronide ABC transporter Nw 1689 Acyl Glucuronide |
atp[c] + Nw 1689 (N-Dealkylated Safinamide)_glc[e] + h2o[c] -> adp[c] + Nw 1689 (N-Dealkylated Safinamide)_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB06654 |
Nw 1689 (N-Dealkylated Safinamide)_Glc |
Nw 1689 (N-Dealkylated Safinamide)_Glc |
UidP |
Transport of D-Glucuronate Nw 1689 Acyl Glucuronide |
Nw 1689 (N-Dealkylated Safinamide)_glc[e] -> Nw 1689 (N-Dealkylated Safinamide)_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB06654 |
Nw 1689 (N-Dealkylated Safinamide)_Glc |
Nw 1689 (N-Dealkylated Safinamide)_Glc |
UidB |
Glucuronate transport in via proton symport Nw 1689 Acyl Glucuronide |
Nw 1689 (N-Dealkylated Safinamide)_glc[e] + h[e] -> Nw 1689 (N-Dealkylated Safinamide)_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB06654 |
Nw 1689 (N-Dealkylated Safinamide)_Glc |
Nw 1689 (N-Dealkylated Safinamide)_Glc |
UidB |
Glucuronate transport in via proton symport Nw 1689 Acyl Glucuronide, periplasmatic |
h[p] + Nw 1689 (N-Dealkylated Safinamide)_glc[p] -> h[c] + Nw 1689 (N-Dealkylated Safinamide)_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB06654 |
Nw 1689 (N-Dealkylated Safinamide)_Glc |
Nw 1689 (N-Dealkylated Safinamide)_Glc |
n.a. |
Nw 1689 Acyl Glucuronide diffusion extracellular to periplasm |
Nw 1689 (N-Dealkylated Safinamide)_glc[e] <=> Nw 1689 (N-Dealkylated Safinamide)_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB06654 |
Nw 1689 (N-Dealkylated Safinamide) |
Nw 1689 (N-Dealkylated Safinamide) |
n.a. |
beta-glucuronidase reaction product export Nw 1689 (N-Dealkylated Safinamide) |
Nw 1689 (N-Dealkylated Safinamide)[c] -> Nw 1689 (N-Dealkylated Safinamide)[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB06654 |
Nw 1689 (N-Dealkylated Safinamide) |
Nw 1689 (N-Dealkylated Safinamide) |
n.a. |
beta-glucuronidase reaction product export Nw 1689 (N-Dealkylated Safinamide), periplasmatic |
Nw 1689 (N-Dealkylated Safinamide)[c] -> Nw 1689 (N-Dealkylated Safinamide)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB06654 |
Nw 1689 (N-Dealkylated Safinamide) |
Nw 1689 (N-Dealkylated Safinamide) |
n.a. |
Nw 1689 (N-Dealkylated Safinamide) diffusion extracellular to periplasm |
Nw 1689 (N-Dealkylated Safinamide)[e] <=> Nw 1689 (N-Dealkylated Safinamide)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB06147 |
Sulfathiazole_Glc |
Sulfathiazole |
UidAc |
Sulfathiazole Glucuronide beta-glucuronidase |
Sulfathiazole_glc[c] + h2o[c] -> Sulfathiazole[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB06147 |
Sulfathiazole_Glc |
Sulfathiazole |
UidAe |
Sulfathiazole Glucuronide beta-glucuronidase extracellular |
Sulfathiazole_glc[e] + h2o[e] -> Sulfathiazole[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB06147 |
Sulfathiazole_Glc |
Sulfathiazole |
UidAe |
Sulfathiazole Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Sulfathiazole_glc[p] -> glcur[p] + Sulfathiazole[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB06147 |
Sulfathiazole_Glc |
Sulfathiazole_Glc |
UidABC |
Predicted glucuronide ABC transporter Sulfathiazole Glucuronide |
atp[c] + Sulfathiazole_glc[e] + h2o[c] -> adp[c] + Sulfathiazole_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB06147 |
Sulfathiazole_Glc |
Sulfathiazole_Glc |
UidP |
Transport of D-Glucuronate Sulfathiazole Glucuronide |
Sulfathiazole_glc[e] -> Sulfathiazole_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB06147 |
Sulfathiazole_Glc |
Sulfathiazole_Glc |
UidB |
Glucuronate transport in via proton symport Sulfathiazole Glucuronide |
Sulfathiazole_glc[e] + h[e] -> Sulfathiazole_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB06147 |
Sulfathiazole_Glc |
Sulfathiazole_Glc |
UidB |
Glucuronate transport in via proton symport Sulfathiazole Glucuronide, periplasmatic |
h[p] + Sulfathiazole_glc[p] -> h[c] + Sulfathiazole_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB06147 |
Sulfathiazole_Glc |
Sulfathiazole_Glc |
n.a. |
Sulfathiazole Glucuronide diffusion extracellular to periplasm |
Sulfathiazole_glc[e] <=> Sulfathiazole_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB06147 |
Sulfathiazole |
Sulfathiazole |
n.a. |
beta-glucuronidase reaction product export Sulfathiazole |
Sulfathiazole[c] -> Sulfathiazole[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB06147 |
Sulfathiazole |
Sulfathiazole |
n.a. |
beta-glucuronidase reaction product export Sulfathiazole, periplasmatic |
Sulfathiazole[c] -> Sulfathiazole[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB06147 |
Sulfathiazole |
Sulfathiazole |
n.a. |
Sulfathiazole diffusion extracellular to periplasm |
Sulfathiazole[e] <=> Sulfathiazole[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00641 |
Simvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acyl-Glucuronide |
Simvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Dihydroxy Acid Form |
UidAc |
simvastatin-acyl-glucuronide beta-glucuronidase |
simvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acyl-glucuronide[c] + h2o[c] -> simvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin dihydroxy acid form[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00641 |
Simvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acyl-Glucuronide |
Simvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Dihydroxy Acid Form |
UidAe |
simvastatin-acyl-glucuronide beta-glucuronidase extracellular |
simvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acyl-glucuronide[e] + h2o[e] -> simvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin dihydroxy acid form[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00641 |
Simvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acyl-Glucuronide |
Simvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Dihydroxy Acid Form |
UidAe |
simvastatin-acyl-glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + simvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acyl-glucuronide[p] -> glcur[p] + h[p] + simvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin dihydroxy acid form[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00641 |
Simvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acyl-Glucuronide |
Simvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acyl-Glucuronide |
UidABC |
Predicted glucuronide ABC transporter simvastatin-acyl-glucuronide |
atp[c] + simvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acyl-glucuronide[e] + h2o[c] -> adp[c] + simvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acyl-glucuronide[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00641 |
Simvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acyl-Glucuronide |
Simvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acyl-Glucuronide |
UidP |
Transport of D-Glucuronate simvastatin-acyl-glucuronide |
simvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acyl-glucuronide[e] -> simvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acyl-glucuronide[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00641 |
Simvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acyl-Glucuronide |
Simvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acyl-Glucuronide |
UidB |
Glucuronate transport in via proton symport simvastatin-acyl-glucuronide |
simvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acyl-glucuronide[e] + h[e] -> simvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acyl-glucuronide[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00641 |
Simvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acyl-Glucuronide |
Simvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acyl-Glucuronide |
UidB |
Glucuronate transport in via proton symport simvastatin-acyl-glucuronide, periplasmatic |
h[p] + simvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acyl-glucuronide[p] -> h[c] + simvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acyl-glucuronide[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00641 |
Simvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acyl-Glucuronide |
Simvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-Acyl-Glucuronide |
n.a. |
simvastatin-acyl-glucuronide diffusion extracellular to periplasm |
simvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acyl-glucuronide[e] <=> simvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin-acyl-glucuronide[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
2-Sulfamoylacetylphenol_Glc |
2-Sulfamoylacetylphenol |
UidAc |
2-Sulfamoylacetylphenol Glucuronide beta-glucuronidase |
2-Sulfamoylacetylphenol_glc[c] + h2o[c] -> 2-Sulfamoylacetylphenol[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
2-Sulfamoylacetylphenol_Glc |
2-Sulfamoylacetylphenol |
UidAe |
2-Sulfamoylacetylphenol Glucuronide beta-glucuronidase extracellular |
2-Sulfamoylacetylphenol_glc[e] + h2o[e] -> 2-Sulfamoylacetylphenol[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
2-Sulfamoylacetylphenol_Glc |
2-Sulfamoylacetylphenol |
UidAe |
2-Sulfamoylacetylphenol Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + 2-Sulfamoylacetylphenol_glc[p] -> glcur[p] + h[p] + 2-Sulfamoylacetylphenol[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| n.a. |
2-Sulfamoylacetylphenol_Glc |
2-Sulfamoylacetylphenol_Glc |
UidABC |
Predicted glucuronide ABC transporter 2-Sulfamoylacetylphenol Glucuronide |
atp[c] + 2-Sulfamoylacetylphenol_glc[e] + h2o[c] -> adp[c] + 2-Sulfamoylacetylphenol_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
2-Sulfamoylacetylphenol_Glc |
2-Sulfamoylacetylphenol_Glc |
UidP |
Transport of D-Glucuronate 2-Sulfamoylacetylphenol Glucuronide |
2-Sulfamoylacetylphenol_glc[e] -> 2-Sulfamoylacetylphenol_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
2-Sulfamoylacetylphenol_Glc |
2-Sulfamoylacetylphenol_Glc |
UidB |
Glucuronate transport in via proton symport 2-Sulfamoylacetylphenol Glucuronide |
2-Sulfamoylacetylphenol_glc[e] + h[e] -> 2-Sulfamoylacetylphenol_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
2-Sulfamoylacetylphenol_Glc |
2-Sulfamoylacetylphenol_Glc |
UidB |
Glucuronate transport in via proton symport 2-Sulfamoylacetylphenol Glucuronide, periplasmatic |
h[p] + 2-Sulfamoylacetylphenol_glc[p] -> h[c] + 2-Sulfamoylacetylphenol_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
2-Sulfamoylacetylphenol_Glc |
2-Sulfamoylacetylphenol_Glc |
n.a. |
2-Sulfamoylacetylphenol Glucuronide diffusion extracellular to periplasm |
2-Sulfamoylacetylphenol_glc[e] <=> 2-Sulfamoylacetylphenol_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
2-Sulfamoylacetylphenol |
2-Sulfamoylacetylphenol |
n.a. |
beta-glucuronidase reaction product export 2-Sulfamoylacetylphenol |
2-Sulfamoylacetylphenol[c] -> 2-Sulfamoylacetylphenol[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
2-Sulfamoylacetylphenol |
2-Sulfamoylacetylphenol |
n.a. |
beta-glucuronidase reaction product export 2-Sulfamoylacetylphenol, periplasmatic |
2-Sulfamoylacetylphenol[c] -> 2-Sulfamoylacetylphenol[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
2-Sulfamoylacetylphenol |
2-Sulfamoylacetylphenol |
n.a. |
2-Sulfamoylacetylphenol diffusion extracellular to periplasm |
2-Sulfamoylacetylphenol[e] <=> 2-Sulfamoylacetylphenol[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00641 |
Simvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Dihydroxy Acid Form |
Simvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Dihydroxy Acid Form |
n.a. |
beta-glucuronidase reaction product export simvastatin dihydroxy acid form |
simvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin dihydroxy acid form[c] -> simvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin dihydroxy acid form[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00641 |
Simvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Dihydroxy Acid Form |
Simvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Dihydroxy Acid Form |
n.a. |
beta-glucuronidase reaction product export simvastatin dihydroxy acid form, periplasmatic |
simvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin dihydroxy acid form[c] -> simvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin dihydroxy acid form[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00641 |
Simvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Dihydroxy Acid Form |
Simvasn-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin Dihydroxy Acid Form |
n.a. |
simvastatin dihydroxy acid form diffusion extracellular to periplasm |
simvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin dihydroxy acid form[e] <=> simvasN-(2-Methyl-3-Chlorophenyl)-Anthranilic Acidin dihydroxy acid form[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00762 |
Sn-38 (Active Me1,2,4-Triaminobenzeneolite Of Irinotecan)G |
Sn-38 (Active Me1,2,4-Triaminobenzeneolite Of Irinotecan) |
UidAc |
SN38 glucuronide beta-glucuronidase |
SN-38 (active me1,2,4-Triaminobenzeneolite of irinotecan)g[c] + h2o[c] -> SN-38 (active me1,2,4-Triaminobenzeneolite of irinotecan)[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 22740943 |
| DB00762 |
Sn-38 (Active Me1,2,4-Triaminobenzeneolite Of Irinotecan)G |
Sn-38 (Active Me1,2,4-Triaminobenzeneolite Of Irinotecan) |
UidAe |
SN38 glucuronide beta-glucuronidase extracellular |
SN-38 (active me1,2,4-Triaminobenzeneolite of irinotecan)g[e] + h2o[e] -> SN-38 (active me1,2,4-Triaminobenzeneolite of irinotecan)[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 22740943 |
| DB00762 |
Sn-38 (Active Me1,2,4-Triaminobenzeneolite Of Irinotecan)G |
Sn-38 (Active Me1,2,4-Triaminobenzeneolite Of Irinotecan) |
UidAe |
SN38 glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + SN-38 (active me1,2,4-Triaminobenzeneolite of irinotecan)g[p] -> glcur[p] + h[p] + SN-38 (active me1,2,4-Triaminobenzeneolite of irinotecan)[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 22740943 |
| DB00762 |
Sn-38 (Active Me1,2,4-Triaminobenzeneolite Of Irinotecan)G |
Sn-38 (Active Me1,2,4-Triaminobenzeneolite Of Irinotecan)G |
UidABC |
Predicted glucuronide ABC transporter SN38 glucuronide |
atp[c] + SN-38 (active me1,2,4-Triaminobenzeneolite of irinotecan)g[e] + h2o[c] -> adp[c] + SN-38 (active me1,2,4-Triaminobenzeneolite of irinotecan)g[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00762 |
Sn-38 (Active Me1,2,4-Triaminobenzeneolite Of Irinotecan)G |
Sn-38 (Active Me1,2,4-Triaminobenzeneolite Of Irinotecan)G |
UidP |
Transport of D-Glucuronate SN38 glucuronide |
SN-38 (active me1,2,4-Triaminobenzeneolite of irinotecan)g[e] -> SN-38 (active me1,2,4-Triaminobenzeneolite of irinotecan)g[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00762 |
Sn-38 (Active Me1,2,4-Triaminobenzeneolite Of Irinotecan)G |
Sn-38 (Active Me1,2,4-Triaminobenzeneolite Of Irinotecan)G |
UidB |
Glucuronate transport in via proton symport SN38 glucuronide |
SN-38 (active me1,2,4-Triaminobenzeneolite of irinotecan)g[e] + h[e] -> SN-38 (active me1,2,4-Triaminobenzeneolite of irinotecan)g[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00762 |
Sn-38 (Active Me1,2,4-Triaminobenzeneolite Of Irinotecan)G |
Sn-38 (Active Me1,2,4-Triaminobenzeneolite Of Irinotecan)G |
UidB |
Glucuronate transport in via proton symport SN38 glucuronide, periplasmatic |
h[p] + SN-38 (active me1,2,4-Triaminobenzeneolite of irinotecan)g[p] -> h[c] + SN-38 (active me1,2,4-Triaminobenzeneolite of irinotecan)g[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00762 |
Sn-38 (Active Me1,2,4-Triaminobenzeneolite Of Irinotecan)G |
Sn-38 (Active Me1,2,4-Triaminobenzeneolite Of Irinotecan)G |
n.a. |
SN38 glucuronide diffusion extracellular to periplasm |
SN-38 (active me1,2,4-Triaminobenzeneolite of irinotecan)g[e] <=> SN-38 (active me1,2,4-Triaminobenzeneolite of irinotecan)g[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00762 |
Sn-38 (Active Me1,2,4-Triaminobenzeneolite Of Irinotecan) |
Sn-38 (Active Me1,2,4-Triaminobenzeneolite Of Irinotecan) |
n.a. |
beta-glucuronidase reaction product export SN-38 (active metabolite of irinotecan) |
SN-38 (active me1,2,4-Triaminobenzeneolite of irinotecan)[c] -> SN-38 (active me1,2,4-Triaminobenzeneolite of irinotecan)[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00762 |
Sn-38 (Active Me1,2,4-Triaminobenzeneolite Of Irinotecan) |
Sn-38 (Active Me1,2,4-Triaminobenzeneolite Of Irinotecan) |
n.a. |
beta-glucuronidase reaction product export SN-38 (active metabolite of irinotecan), periplasmatic |
SN-38 (active me1,2,4-Triaminobenzeneolite of irinotecan)[c] -> SN-38 (active me1,2,4-Triaminobenzeneolite of irinotecan)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00762 |
Sn-38 (Active Me1,2,4-Triaminobenzeneolite Of Irinotecan) |
Sn-38 (Active Me1,2,4-Triaminobenzeneolite Of Irinotecan) |
n.a. |
SN-38 diffusion extracellular to periplasm |
SN-38 (active me1,2,4-Triaminobenzeneolite of irinotecan)[e] <=> SN-38 (active me1,2,4-Triaminobenzeneolite of irinotecan)[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01138 |
Sulfinpyrazone_Glc |
Sulfinpyrazone |
UidAc |
Sulfinpyrazone Glucuronide beta-glucuronidase |
Sulfinpyrazone_glc[c] + h2o[c] -> Sulfinpyrazone[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01138 |
Sulfinpyrazone_Glc |
Sulfinpyrazone |
UidAe |
Sulfinpyrazone Glucuronide beta-glucuronidase extracellular |
Sulfinpyrazone_glc[e] + h2o[e] -> Sulfinpyrazone[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01138 |
Sulfinpyrazone_Glc |
Sulfinpyrazone |
UidAe |
Sulfinpyrazone Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Sulfinpyrazone_glc[p] -> glcur[p] + Sulfinpyrazone[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01138 |
Sulfinpyrazone_Glc |
Sulfinpyrazone_Glc |
UidABC |
Predicted glucuronide ABC transporter Sulfinpyrazone Glucuronide |
atp[c] + Sulfinpyrazone_glc[e] + h2o[c] -> adp[c] + Sulfinpyrazone_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01138 |
Sulfinpyrazone_Glc |
Sulfinpyrazone_Glc |
UidP |
Transport of D-Glucuronate Sulfinpyrazone Glucuronide |
Sulfinpyrazone_glc[e] -> Sulfinpyrazone_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01138 |
Sulfinpyrazone_Glc |
Sulfinpyrazone_Glc |
UidB |
Glucuronate transport in via proton symport Sulfinpyrazone Glucuronide |
Sulfinpyrazone_glc[e] + h[e] -> Sulfinpyrazone_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01138 |
Sulfinpyrazone_Glc |
Sulfinpyrazone_Glc |
UidB |
Glucuronate transport in via proton symport Sulfinpyrazone Glucuronide, periplasmatic |
h[p] + Sulfinpyrazone_glc[p] -> h[c] + Sulfinpyrazone_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01138 |
Sulfinpyrazone_Glc |
Sulfinpyrazone_Glc |
n.a. |
Sulfinpyrazone Glucuronide diffusion extracellular to periplasm |
Sulfinpyrazone_glc[e] <=> Sulfinpyrazone_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01138 |
Sulfinpyrazone_Sfn_Glc |
Sulfinpyrazone_Sfn |
UidAc |
Sulfinpyrazone Sulfone Glucuronide beta-glucuronidase |
Sulfinpyrazone_sfn_glc[c] + h2o[c] -> Sulfinpyrazone_sfn[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01138 |
Sulfinpyrazone_Sfn_Glc |
Sulfinpyrazone_Sfn |
UidAe |
Sulfinpyrazone Sulfone Glucuronide beta-glucuronidase extracellular |
Sulfinpyrazone_sfn_glc[e] + h2o[e] -> Sulfinpyrazone_sfn[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01138 |
Sulfinpyrazone_Sfn_Glc |
Sulfinpyrazone_Sfn |
UidAe |
Sulfinpyrazone Sulfone Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Sulfinpyrazone_sfn_glc[p] -> glcur[p] + Sulfinpyrazone_sfn[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01138 |
Sulfinpyrazone_Sfn_Glc |
Sulfinpyrazone_Sfn_Glc |
UidABC |
Predicted glucuronide ABC transporter Sulfinpyrazone Sulfone Glucuronide |
atp[c] + Sulfinpyrazone_sfn_glc[e] + h2o[c] -> adp[c] + Sulfinpyrazone_sfn_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01138 |
Sulfinpyrazone_Sfn_Glc |
Sulfinpyrazone_Sfn_Glc |
UidP |
Transport of D-Glucuronate Sulfinpyrazone Sulfone Glucuronide |
Sulfinpyrazone_sfn_glc[e] -> Sulfinpyrazone_sfn_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01138 |
Sulfinpyrazone_Sfn_Glc |
Sulfinpyrazone_Sfn_Glc |
UidB |
Glucuronate transport in via proton symport Sulfinpyrazone Sulfone Glucuronide |
Sulfinpyrazone_sfn_glc[e] + h[e] -> Sulfinpyrazone_sfn_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01138 |
Sulfinpyrazone_Sfn_Glc |
Sulfinpyrazone_Sfn_Glc |
UidB |
Glucuronate transport in via proton symport Sulfinpyrazone Sulfone Glucuronide, periplasmatic |
h[p] + Sulfinpyrazone_sfn_glc[p] -> h[c] + Sulfinpyrazone_sfn_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01138 |
Sulfinpyrazone_Sfn_Glc |
Sulfinpyrazone_Sfn_Glc |
n.a. |
Sulfinpyrazone Sulfone Glucuronide diffusion extracellular to periplasm |
Sulfinpyrazone_sfn_glc[e] <=> Sulfinpyrazone_sfn_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01138 |
Sulfinpyrazone_Sfn |
Sulfinpyrazone_Sfn |
n.a. |
beta-glucuronidase reaction product export Sulfinpyrazone Sulfone |
Sulfinpyrazone_sfn[c] -> Sulfinpyrazone_sfn[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01138 |
Sulfinpyrazone_Sfn |
Sulfinpyrazone_Sfn |
n.a. |
beta-glucuronidase reaction product export Sulfinpyrazone Sulfone, periplasmatic |
Sulfinpyrazone_sfn[c] -> Sulfinpyrazone_sfn[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01138 |
Sulfinpyrazone_Sfn |
Sulfinpyrazone_Sfn |
n.a. |
Sulfinpyrazone Sulfone diffusion extracellular to periplasm |
Sulfinpyrazone_sfn[e] <=> Sulfinpyrazone_sfn[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01138 |
Sulfinpyrazone |
Sulfinpyrazone |
n.a. |
beta-glucuronidase reaction product export Sulfinpyrazone |
Sulfinpyrazone[c] -> Sulfinpyrazone[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01138 |
Sulfinpyrazone |
Sulfinpyrazone |
n.a. |
beta-glucuronidase reaction product export Sulfinpyrazone, periplasmatic |
Sulfinpyrazone[c] -> Sulfinpyrazone[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01138 |
Sulfinpyrazone |
Sulfinpyrazone |
n.a. |
Sulfinpyrazone diffusion extracellular to periplasm |
Sulfinpyrazone[e] <=> Sulfinpyrazone[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB11998 |
Sorivudine |
Sorivudine |
n.a. |
Sorivudine transport in via proton symport |
h[e] + Sorivudine[e] -> h[c] + Sorivudine[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB11998 |
Sorivudine |
Sorivudine |
n.a. |
Sorivudine transport in via proton symport, periplasmatic |
h[p] + Sorivudine[p] -> h[c] + Sorivudine[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB11998 |
Sorivudine |
Sorivudine |
n.a. |
Sorivudine diffusion extracellular to periplasm |
Sorivudine[e] <=> Sorivudine[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Sulfasalazine |
5-Aminosalicylic Acid (Mesalamine) |
AzNAD |
Sulfasalazine Microbiota azo-reduction (NAD) |
Sulfasalazine[c] + 2 nadh[c] + 3 h[c] -> 5-Aminosalicylic Acid (Mesalamine)[c] + Sulfapyridine[c] + 2 nad[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 25091594, PMID: 26261286 |
| n.a. |
Sulfasalazine |
5-Aminosalicylic Acid (Mesalamine) |
AzNADP |
Sulfasalazine Microbiota azo-reduction (NADP) |
Sulfasalazine[c] + 2 nadph[c] + 3 h[c] -> 5-Aminosalicylic Acid (Mesalamine)[c] + Sulfapyridine[c] + 2 nadp[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 25091594, PMID: 26261286 |
| DB00795 |
Sulfasalazine |
Sulfasalazine |
AzorDMT |
Sulfasalazine transport via proton symport |
Sulfasalazine[e] + h[e] <=> Sulfasalazine[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00795 |
Sulfasalazine |
Sulfasalazine |
AzorDMT |
Sulfasalazine transport via proton symport, periplasmatic |
h[p] + Sulfasalazine[p] <=> h[c] + Sulfasalazine[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00795 |
Sulfasalazine |
Sulfasalazine |
n.a. |
Sulfasalazine diffusion extracellular to periplasm |
Sulfasalazine[e] <=> Sulfasalazine[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01261 |
Sitagliptin_M3 |
Sitagliptin |
UidAc |
Sitagliptin M3 (Ether Glucuronide Conjugate Of A Hydroxylated Derivative) beta-glucuronidase |
Sitagliptin_m3[c] + h2o[c] -> Sitagliptin[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01261 |
Sitagliptin_M3 |
Sitagliptin |
UidAe |
Sitagliptin M3 (Ether Glucuronide Conjugate Of A Hydroxylated Derivative) beta-glucuronidase extracellular |
Sitagliptin_m3[e] + h2o[e] -> Sitagliptin[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01261 |
Sitagliptin_M3 |
Sitagliptin |
UidAe |
Sitagliptin M3 (Ether Glucuronide Conjugate Of A Hydroxylated Derivative) beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Sitagliptin_m3[p] -> glcur[p] + Sitagliptin[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01261 |
Sitagliptin_M3 |
Sitagliptin_M3 |
UidABC |
Predicted glucuronide ABC transporter Sitagliptin M3 (Ether Glucuronide Conjugate Of A Hydroxylated Derivative) |
atp[c] + Sitagliptin_m3[e] + h2o[c] -> adp[c] + Sitagliptin_m3[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01261 |
Sitagliptin_M3 |
Sitagliptin_M3 |
UidP |
Transport of D-Glucuronate Sitagliptin M3 (Ether Glucuronide Conjugate Of A Hydroxylated Derivative) |
Sitagliptin_m3[e] -> Sitagliptin_m3[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01261 |
Sitagliptin_M3 |
Sitagliptin_M3 |
UidB |
Glucuronate transport in via proton symport Sitagliptin M3 (Ether Glucuronide Conjugate Of A Hydroxylated Derivative) |
Sitagliptin_m3[e] + h[e] -> Sitagliptin_m3[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01261 |
Sitagliptin_M3 |
Sitagliptin_M3 |
UidB |
Glucuronate transport in via proton symport Sitagliptin M3 (Ether Glucuronide Conjugate Of A Hydroxylated Derivative), periplasm... |
h[p] + Sitagliptin_m3[p] -> h[c] + Sitagliptin_m3[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01261 |
Sitagliptin_M3 |
Sitagliptin_M3 |
n.a. |
Sitagliptin M3 (Ether Glucuronide Conjugate Of A Hydroxylated Derivative) diffusion extracellular to periplasm |
Sitagliptin_m3[e] <=> Sitagliptin_m3[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01261 |
Sitagliptin_M4 |
Sitagliptin |
UidAc |
Sitagliptin M4 (N-Carbomyl Glucuronide Conjugate) beta-glucuronidase |
Sitagliptin_m4[c] + h2o[c] + h[c] -> Sitagliptin[c] + glcur[c] + co2[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01261 |
Sitagliptin_M4 |
Sitagliptin |
UidAe |
Sitagliptin M4 (N-Carbomyl Glucuronide Conjugate) beta-glucuronidase extracellular |
Sitagliptin_m4[e] + h2o[e] + h[e] -> Sitagliptin[e] + glcur[e] + co2[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01261 |
Sitagliptin_M4 |
Sitagliptin |
UidAe |
Sitagliptin M4 (N-Carbomyl Glucuronide Conjugate) beta-glucuronidase extracellular, periplasmatic |
h2o[p] + h[p] + Sitagliptin_m4[p] -> co2[p] + glcur[p] + Sitagliptin[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB01261 |
Sitagliptin_M4 |
Sitagliptin_M4 |
UidABC |
Predicted glucuronide ABC transporter Sitagliptin M4 (N-Carbomyl Glucuronide Conjugate) |
atp[c] + Sitagliptin_m4[e] + h2o[c] -> adp[c] + Sitagliptin_m4[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01261 |
Sitagliptin_M4 |
Sitagliptin_M4 |
UidP |
Transport of D-Glucuronate Sitagliptin M4 (N-Carbomyl Glucuronide Conjugate) |
Sitagliptin_m4[e] -> Sitagliptin_m4[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01261 |
Sitagliptin_M4 |
Sitagliptin_M4 |
UidB |
Glucuronate transport in via proton symport Sitagliptin M4 (N-Carbomyl Glucuronide Conjugate) |
Sitagliptin_m4[e] + h[e] -> Sitagliptin_m4[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01261 |
Sitagliptin_M4 |
Sitagliptin_M4 |
UidB |
Glucuronate transport in via proton symport Sitagliptin M4 (N-Carbomyl Glucuronide Conjugate), periplasmatic |
h[p] + Sitagliptin_m4[p] -> h[c] + Sitagliptin_m4[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01261 |
Sitagliptin_M4 |
Sitagliptin_M4 |
n.a. |
Sitagliptin M4 (N-Carbomyl Glucuronide Conjugate) diffusion extracellular to periplasm |
Sitagliptin_m4[e] <=> Sitagliptin_m4[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01261 |
Sitagliptin |
Sitagliptin |
n.a. |
beta-glucuronidase reaction product export Sitagliptin |
Sitagliptin[c] -> Sitagliptin[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB01261 |
Sitagliptin |
Sitagliptin |
n.a. |
beta-glucuronidase reaction product export Sitagliptin, periplasmatic |
Sitagliptin[c] -> Sitagliptin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01261 |
Sitagliptin |
Sitagliptin |
n.a. |
Sitagliptin diffusion extracellular to periplasm |
Sitagliptin[e] <=> Sitagliptin[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Sulfoacetate |
N.A. |
n.a. |
sulfoacetate transport via ABC system, periplasmatic |
atp[c] + h2o[c] + sulfac[p] -> adp[c] + h[c] + pi[c] + sulfac[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Sulfoacetate |
N.A. |
n.a. |
sulfoacetate diffusion extracellular to periplasm |
sulfac[e] <=> sulfac[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Sulfoacetate |
N.A. |
n.a. |
sulfoacetate diffusion extracellular to periplasm |
sulfac[e] <=> sulfac[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00891 |
Sulfapyridine |
Sulfapyridine |
AzorDMT |
Sulfapyridine transport via proton symport |
Sulfapyridine[e] + h[e] <=> Sulfapyridine[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00891 |
Sulfapyridine |
Sulfapyridine |
AzorDMT |
Sulfapyridine transport via proton symport, periplasmatic |
h[p] + Sulfapyridine[p] <=> h[c] + Sulfapyridine[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00891 |
Sulfapyridine |
Sulfapyridine |
n.a. |
Sulfapyridine diffusion extracellular to periplasm |
Sulfapyridine[e] <=> Sulfapyridine[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01068 |
7-Aminoclonazepam |
7-Aminoclonazepam |
n.a. |
7-Aminoclonazepam transport, reversible, hypothetical reaction, periplasmatic |
7-Aminoclonazepam[p] <=> 7-Aminoclonazepam[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
1,2,4-Triaminobenzene |
1,2,4-Triaminobenzene |
AzorDMT |
1 2 4-Triaminobenzene transport via proton symport |
1,2,4-Triaminobenzene[e] + h[e] <=> 1,2,4-Triaminobenzene[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
1,2,4-Triaminobenzene |
1,2,4-Triaminobenzene |
AzorDMT |
1 2 4-Triaminobenzene transport via proton symport, periplasmatic |
h[p] + 1,2,4-Triaminobenzene[p] <=> h[c] + 1,2,4-Triaminobenzene[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
1,2,4-Triaminobenzene |
1,2,4-Triaminobenzene |
n.a. |
1,2,4-Triaminobenzene diffusion extracellular to periplasm |
1,2,4-Triaminobenzene[e] <=> 1,2,4-Triaminobenzene[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
7-Amino Nitrozepam |
7-Amino Nitrozepam |
n.a. |
7-Amino Nitrozepam transport, reversible, hypothetical reaction, periplasmatic |
7-Amino Nitrozepam[p] <=> 7-Amino Nitrozepam[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid |
Tolfenamic Acid |
UidAc |
N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid beta-glucuronidase |
N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid[c] + h2o[c] -> Tolfenamic Acid[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB04166 |
N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid |
Tolfenamic Acid |
UidAe |
N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid beta-glucuronidase extracellular |
N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid[e] + h2o[e] -> Tolfenamic Acid[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB04166 |
N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid |
Tolfenamic Acid |
UidAe |
N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid beta-glucuronidase extracellular, periplasmatic |
h2o[p] + N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid[p] -> glcur[p] + h[p] + Tolfenamic Acid[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB04166 |
N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid |
N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid |
UidABC |
Predicted glucuronide ABC transporter N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid |
atp[c] + N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid[e] + h2o[c] -> adp[c] + N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid |
N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid |
UidP |
Transport of D-Glucuronate N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid |
N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid[e] -> N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid |
N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid |
UidB |
Glucuronate transport in via proton symport N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid |
N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid[e] + h[e] -> N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid |
N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid |
UidB |
Glucuronate transport in via proton symport N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid, periplasmatic |
h[p] + N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid[p] -> h[c] + N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid |
N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid |
n.a. |
N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid diffusion extracellular to periplasm |
N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid[e] <=> N-(2-Methyl-3-Chlorophenyl)-Anthranilic Acid[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00446 |
Chloramphenicol |
Chloramphenicol |
n.a. |
Chloramphenicol transport, reversible, hypothetical reaction, periplasmatic |
Chloramphenicol[p] <=> Chloramphenicol[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| n.a. |
Taurochenodeoxycholate |
Chenodeoxycholate |
BSH |
Taurochenodeoxycholate hydrolysis by bile salt hydrolase (EC 3.5.1.24, EC 3.5.1.74) |
h2o[e] + Taurochenodeoxycholate[e] -> chenodeoxyCholate[e] + h[e] + Taurine[e] |
Bile acid metabolism |
Metabolism |
Experimental Subsystems |
Bile acid metabolism |
n.a. |
PMID: 10194664 |
| n.a. |
Taurochenodeoxycholate |
Chenodeoxycholate |
BSH |
Taurochenodeoxycholate hydrolysis by bile salt hydrolase (EC 3.5.1.24, EC 3.5.1.74), periplasmatic |
h2o[p] + Taurochenodeoxycholate[p] -> chenodeoxyCholate[p] + h[p] + Taurine[p] |
Bile acid metabolism |
Metabolism |
Experimental Subsystems |
Bile acid metabolism |
n.a. |
PMID: 10194664 |
| n.a. |
Taurocholate |
Cholate |
BSH |
Taurocholate hydrolysis by bile salt hydrolase (EC 3.5.1.24) |
h2o[e] + taurocholate[e] -> Cholate[e] + h[e] + Taurine[e] |
Bile acid metabolism |
Metabolism |
Experimental Subsystems |
Bile acid metabolism |
n.a. |
PMID: 10194664 |
| n.a. |
Taurocholate |
Cholate |
BSH |
Taurocholate hydrolysis by bile salt hydrolase (EC 3.5.1.24), periplasmatic |
h2o[p] + taurocholate[p] -> Cholate[p] + h[p] + Taurine[p] |
Bile acid metabolism |
Metabolism |
Experimental Subsystems |
Bile acid metabolism |
n.a. |
PMID: 10194664 |
| DB01068 |
Clonazepam |
Clonazepam |
n.a. |
Clonazepam transport, reversible, hypothetical reaction, periplasmatic |
Clonazepam[p] <=> Clonazepam[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00197 |
Troglitazone_Glc |
Troglitazone |
UidAc |
Troglitazone Glucuronide beta-glucuronidase |
Troglitazone_glc[c] + h2o[c] -> Troglitazone[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 12433820 |
| DB00197 |
Troglitazone_Glc |
Troglitazone |
UidAe |
Troglitazone Glucuronide beta-glucuronidase extracellular |
Troglitazone_glc[e] + h2o[e] -> Troglitazone[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 12433820 |
| DB00197 |
Troglitazone_Glc |
Troglitazone |
UidAe |
Troglitazone Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Troglitazone_glc[p] -> glcur[p] + Troglitazone[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 12433820 |
| DB00197 |
Troglitazone_Glc |
Troglitazone_Glc |
UidABC |
Predicted glucuronide ABC transporter Troglitazone Glucuronide |
atp[c] + Troglitazone_glc[e] + h2o[c] -> adp[c] + Troglitazone_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00197 |
Troglitazone_Glc |
Troglitazone_Glc |
UidP |
Transport of D-Glucuronate Troglitazone Glucuronide |
Troglitazone_glc[e] -> Troglitazone_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00197 |
Troglitazone_Glc |
Troglitazone_Glc |
UidB |
Glucuronate transport in via proton symport Troglitazone Glucuronide |
Troglitazone_glc[e] + h[e] -> Troglitazone_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00197 |
Troglitazone_Glc |
Troglitazone_Glc |
UidB |
Glucuronate transport in via proton symport Troglitazone Glucuronide, periplasmatic |
h[p] + Troglitazone_glc[p] -> h[c] + Troglitazone_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00197 |
Troglitazone_Glc |
Troglitazone_Glc |
n.a. |
Troglitazone Glucuronide diffusion extracellular to periplasm |
Troglitazone_glc[e] <=> Troglitazone_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00197 |
Troglitazone |
Troglitazone |
n.a. |
beta-glucuronidase reaction product export Troglitazone |
Troglitazone[c] -> Troglitazone[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00197 |
Troglitazone |
Troglitazone |
n.a. |
beta-glucuronidase reaction product export Troglitazone, periplasmatic |
Troglitazone[c] -> Troglitazone[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00197 |
Troglitazone |
Troglitazone |
n.a. |
Troglitazone diffusion extracellular to periplasm |
Troglitazone[e] <=> Troglitazone[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Thsacetaminophen |
Thsacetaminophen |
n.a. |
beta-glucuronidase reaction product export thiomethyl-sulphoxide-conjugate-acetaminophen |
thsAcetaminophen[c] -> thsAcetaminophen[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_1A |
Tolfenamic Acid_1A |
n.a. |
beta-glucuronidase reaction product export Tolfenamic Acid 1A |
Tolfenamic Acid_1a[c] -> Tolfenamic Acid_1a[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_1A |
Tolfenamic Acid_1A |
n.a. |
beta-glucuronidase reaction product export Tolfenamic Acid 1A, periplasmatic |
Tolfenamic Acid_1a[c] -> Tolfenamic Acid_1a[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_1A |
Tolfenamic Acid_1A |
n.a. |
Tolfenamic Acid 1A diffusion extracellular to periplasm |
Tolfenamic Acid_1a[e] <=> Tolfenamic Acid_1a[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_1B |
Tolfenamic Acid_1B |
n.a. |
beta-glucuronidase reaction product export Tolfenamic Acid 1B |
Tolfenamic Acid_1b[c] -> Tolfenamic Acid_1b[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_1B |
Tolfenamic Acid_1B |
n.a. |
beta-glucuronidase reaction product export Tolfenamic Acid 1B, periplasmatic |
Tolfenamic Acid_1b[c] -> Tolfenamic Acid_1b[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_1B |
Tolfenamic Acid_1B |
n.a. |
Tolfenamic Acid 1B diffusion extracellular to periplasm |
Tolfenamic Acid_1b[e] <=> Tolfenamic Acid_1b[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_1X |
Tolfenamic Acid_1X |
n.a. |
beta-glucuronidase reaction product export Tolfenamic Acid 1X |
Tolfenamic Acid_1x[c] -> Tolfenamic Acid_1x[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_1X |
Tolfenamic Acid_1X |
n.a. |
beta-glucuronidase reaction product export Tolfenamic Acid 1X, periplasmatic |
Tolfenamic Acid_1x[c] -> Tolfenamic Acid_1x[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_1X |
Tolfenamic Acid_1X |
n.a. |
Tolfenamic Acid 1X diffusion extracellular to periplasm |
Tolfenamic Acid_1x[e] <=> Tolfenamic Acid_1x[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_2A |
Tolfenamic Acid_2A |
n.a. |
beta-glucuronidase reaction product export Tolfenamic Acid 2A |
Tolfenamic Acid_2a[c] -> Tolfenamic Acid_2a[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_2A |
Tolfenamic Acid_2A |
n.a. |
beta-glucuronidase reaction product export Tolfenamic Acid 2A, periplasmatic |
Tolfenamic Acid_2a[c] -> Tolfenamic Acid_2a[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_2A |
Tolfenamic Acid_2A |
n.a. |
Tolfenamic Acid 2A diffusion extracellular to periplasm |
Tolfenamic Acid_2a[e] <=> Tolfenamic Acid_2a[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_2 |
Tolfenamic Acid_2 |
n.a. |
beta-glucuronidase reaction product export Tolfenamic Acid 2 |
Tolfenamic Acid_2[c] -> Tolfenamic Acid_2[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_2 |
Tolfenamic Acid_2 |
n.a. |
beta-glucuronidase reaction product export Tolfenamic Acid 2, periplasmatic |
Tolfenamic Acid_2[c] -> Tolfenamic Acid_2[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_2 |
Tolfenamic Acid_2 |
n.a. |
Tolfenamic Acid 2 diffusion extracellular to periplasm |
Tolfenamic Acid_2[e] <=> Tolfenamic Acid_2[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_3 |
Tolfenamic Acid_3 |
n.a. |
beta-glucuronidase reaction product export Tolfenamic Acid 3 |
Tolfenamic Acid_3[c] -> Tolfenamic Acid_3[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_3 |
Tolfenamic Acid_3 |
n.a. |
beta-glucuronidase reaction product export Tolfenamic Acid 3, periplasmatic |
Tolfenamic Acid_3[c] -> Tolfenamic Acid_3[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_3 |
Tolfenamic Acid_3 |
n.a. |
Tolfenamic Acid 3 diffusion extracellular to periplasm |
Tolfenamic Acid_3[e] <=> Tolfenamic Acid_3[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_4 |
Tolfenamic Acid_4 |
n.a. |
beta-glucuronidase reaction product export Tolfenamic Acid 4 |
Tolfenamic Acid_4[c] -> Tolfenamic Acid_4[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_4 |
Tolfenamic Acid_4 |
n.a. |
beta-glucuronidase reaction product export Tolfenamic Acid 4, periplasmatic |
Tolfenamic Acid_4[c] -> Tolfenamic Acid_4[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_4 |
Tolfenamic Acid_4 |
n.a. |
Tolfenamic Acid 4 diffusion extracellular to periplasm |
Tolfenamic Acid_4[e] <=> Tolfenamic Acid_4[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M1 |
Tolfenamic Acid_2 |
UidAc |
N-(2-Hydroxymethyl-3-Chlorophenyl)-Anthranilic Acid beta-glucuronidase |
Tolfenamic Acid_m1[c] + h2o[c] -> Tolfenamic Acid_2[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M1 |
Tolfenamic Acid_2 |
UidAe |
N-(2-Hydroxymethyl-3-Chlorophenyl)-Anthranilic Acid beta-glucuronidase extracellular |
Tolfenamic Acid_m1[e] + h2o[e] -> Tolfenamic Acid_2[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M1 |
Tolfenamic Acid_2 |
UidAe |
N-(2-Hydroxymethyl-3-Chlorophenyl)-Anthranilic Acid beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Tolfenamic Acid_m1[p] -> glcur[p] + h[p] + Tolfenamic Acid_2[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M1 |
Tolfenamic Acid_M1 |
UidABC |
Predicted glucuronide ABC transporter N-(2-Hydroxymethyl-3-Chlorophenyl)-Anthranilic Acid |
atp[c] + Tolfenamic Acid_m1[e] + h2o[c] -> adp[c] + Tolfenamic Acid_m1[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M1 |
Tolfenamic Acid_M1 |
UidP |
Transport of D-Glucuronate N-(2-Hydroxymethyl-3-Chlorophenyl)-Anthranilic Acid |
Tolfenamic Acid_m1[e] -> Tolfenamic Acid_m1[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M1 |
Tolfenamic Acid_M1 |
UidB |
Glucuronate transport in via proton symport N-(2-Hydroxymethyl-3-Chlorophenyl)-Anthranilic Acid |
Tolfenamic Acid_m1[e] + h[e] -> Tolfenamic Acid_m1[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M1 |
Tolfenamic Acid_M1 |
UidB |
Glucuronate transport in via proton symport N-(2-Hydroxymethyl-3-Chlorophenyl)-Anthranilic Acid, periplasmatic |
h[p] + Tolfenamic Acid_m1[p] -> h[c] + Tolfenamic Acid_m1[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M1 |
Tolfenamic Acid_M1 |
n.a. |
N-(2-Hydroxymethyl-3-Chlorophenyl)-Anthranilic Acid diffusion extracellular to periplasm |
Tolfenamic Acid_m1[e] <=> Tolfenamic Acid_m1[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M2 |
Tolfenamic Acid_2A |
UidAc |
N-(2-Hydroxymethyl-3-Chloro-4-Hydroxyphenyl)-Anthranilic Acid beta-glucuronidase |
Tolfenamic Acid_m2[c] + h2o[c] -> Tolfenamic Acid_2a[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M2 |
Tolfenamic Acid_2A |
UidAe |
N-(2-Hydroxymethyl-3-Chloro-4-Hydroxyphenyl)-Anthranilic Acid beta-glucuronidase extracellular |
Tolfenamic Acid_m2[e] + h2o[e] -> Tolfenamic Acid_2a[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M2 |
Tolfenamic Acid_2A |
UidAe |
N-(2-Hydroxymethyl-3-Chloro-4-Hydroxyphenyl)-Anthranilic Acid beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Tolfenamic Acid_m2[p] -> glcur[p] + h[p] + Tolfenamic Acid_2a[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M2 |
Tolfenamic Acid_M2 |
UidABC |
Predicted glucuronide ABC transporter N-(2-Hydroxymethyl-3-Chloro-4-Hydroxyphenyl)-Anthranilic Acid |
atp[c] + Tolfenamic Acid_m2[e] + h2o[c] -> adp[c] + Tolfenamic Acid_m2[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M2 |
Tolfenamic Acid_M2 |
UidP |
Transport of D-Glucuronate N-(2-Hydroxymethyl-3-Chloro-4-Hydroxyphenyl)-Anthranilic Acid |
Tolfenamic Acid_m2[e] -> Tolfenamic Acid_m2[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M2 |
Tolfenamic Acid_M2 |
UidB |
Glucuronate transport in via proton symport N-(2-Hydroxymethyl-3-Chloro-4-Hydroxyphenyl)-Anthranilic Acid |
Tolfenamic Acid_m2[e] + h[e] -> Tolfenamic Acid_m2[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M2 |
Tolfenamic Acid_M2 |
UidB |
Glucuronate transport in via proton symport N-(2-Hydroxymethyl-3-Chloro-4-Hydroxyphenyl)-Anthranilic Acid, periplasmatic |
h[p] + Tolfenamic Acid_m2[p] -> h[c] + Tolfenamic Acid_m2[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M2 |
Tolfenamic Acid_M2 |
n.a. |
N-(2-Hydroxymethyl-3-Chloro-4-Hydroxyphenyl)-Anthranilic Acid diffusion extracellular to periplasm |
Tolfenamic Acid_m2[e] <=> Tolfenamic Acid_m2[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M3 |
Tolfenamic Acid_3 |
UidAc |
N-(2-Formyl-3-Chlorophenyl) Anthranilic Acid beta-glucuronidase |
Tolfenamic Acid_m3[c] + h2o[c] -> Tolfenamic Acid_3[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M3 |
Tolfenamic Acid_3 |
UidAe |
N-(2-Formyl-3-Chlorophenyl) Anthranilic Acid beta-glucuronidase extracellular |
Tolfenamic Acid_m3[e] + h2o[e] -> Tolfenamic Acid_3[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M3 |
Tolfenamic Acid_3 |
UidAe |
N-(2-Formyl-3-Chlorophenyl) Anthranilic Acid beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Tolfenamic Acid_m3[p] -> glcur[p] + h[p] + Tolfenamic Acid_3[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M3 |
Tolfenamic Acid_M3 |
UidABC |
Predicted glucuronide ABC transporter N-(2-Formyl-3-Chlorophenyl) Anthranilic Acid |
atp[c] + Tolfenamic Acid_m3[e] + h2o[c] -> adp[c] + Tolfenamic Acid_m3[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M3 |
Tolfenamic Acid_M3 |
UidP |
Transport of D-Glucuronate N-(2-Formyl-3-Chlorophenyl) Anthranilic Acid |
Tolfenamic Acid_m3[e] -> Tolfenamic Acid_m3[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M3 |
Tolfenamic Acid_M3 |
UidB |
Glucuronate transport in via proton symport N-(2-Formyl-3-Chlorophenyl) Anthranilic Acid |
Tolfenamic Acid_m3[e] + h[e] -> Tolfenamic Acid_m3[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M3 |
Tolfenamic Acid_M3 |
UidB |
Glucuronate transport in via proton symport N-(2-Formyl-3-Chlorophenyl) Anthranilic Acid, periplasmatic |
h[p] + Tolfenamic Acid_m3[p] -> h[c] + Tolfenamic Acid_m3[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M3 |
Tolfenamic Acid_M3 |
n.a. |
N-(2-Formyl-3-Chlorophenyl) Anthranilic Acid diffusion extracellular to periplasm |
Tolfenamic Acid_m3[e] <=> Tolfenamic Acid_m3[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M4 |
Tolfenamic Acid_1A |
UidAc |
N-(2-Methyl-3- Chloro-4-Hydroxyphenyl)-Anthranilic Acid beta-glucuronidase |
Tolfenamic Acid_m4[c] + h2o[c] -> Tolfenamic Acid_1a[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M4 |
Tolfenamic Acid_1A |
UidAe |
N-(2-Methyl-3- Chloro-4-Hydroxyphenyl)-Anthranilic Acid beta-glucuronidase extracellular |
Tolfenamic Acid_m4[e] + h2o[e] -> Tolfenamic Acid_1a[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M4 |
Tolfenamic Acid_1A |
UidAe |
N-(2-Methyl-3- Chloro-4-Hydroxyphenyl)-Anthranilic Acid beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Tolfenamic Acid_m4[p] -> glcur[p] + h[p] + Tolfenamic Acid_1a[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_M4A |
Tolfenamic Acid_1A |
UidAc |
Tolfenamic Acid M4A beta-glucuronidase |
Tolfenamic Acid_m4a[c] + h2o[c] -> Tolfenamic Acid_1a[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_M4A |
Tolfenamic Acid_1A |
UidAe |
Tolfenamic Acid M4A beta-glucuronidase extracellular |
Tolfenamic Acid_m4a[e] + h2o[e] -> Tolfenamic Acid_1a[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_M4A |
Tolfenamic Acid_1A |
UidAe |
Tolfenamic Acid M4A beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Tolfenamic Acid_m4a[p] -> glcur[p] + h[p] + Tolfenamic Acid_1a[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_M4A |
Tolfenamic Acid_M4A |
UidABC |
Predicted glucuronide ABC transporter Tolfenamic Acid M4A |
atp[c] + Tolfenamic Acid_m4a[e] + h2o[c] -> adp[c] + Tolfenamic Acid_m4a[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M4 |
Tolfenamic Acid_M4 |
UidABC |
Predicted glucuronide ABC transporter N-(2-Methyl-3- Chloro-4-Hydroxyphenyl)-Anthranilic Acid |
atp[c] + Tolfenamic Acid_m4[e] + h2o[c] -> adp[c] + Tolfenamic Acid_m4[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_M4A |
Tolfenamic Acid_M4A |
UidP |
Transport of D-Glucuronate Tolfenamic Acid M4A |
Tolfenamic Acid_m4a[e] -> Tolfenamic Acid_m4a[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_M4A |
Tolfenamic Acid_M4A |
UidB |
Glucuronate transport in via proton symport Tolfenamic Acid M4A |
Tolfenamic Acid_m4a[e] + h[e] -> Tolfenamic Acid_m4a[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_M4A |
Tolfenamic Acid_M4A |
UidB |
Glucuronate transport in via proton symport Tolfenamic Acid M4A, periplasmatic |
h[p] + Tolfenamic Acid_m4a[p] -> h[c] + Tolfenamic Acid_m4a[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_M4A |
Tolfenamic Acid_M4A |
n.a. |
Tolfenamic Acid M4A diffusion extracellular to periplasm |
Tolfenamic Acid_m4a[e] <=> Tolfenamic Acid_m4a[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M4 |
Tolfenamic Acid_M4 |
UidP |
Transport of D-Glucuronate N-(2-Methyl-3- Chloro-4-Hydroxyphenyl)-Anthranilic Acid |
Tolfenamic Acid_m4[e] -> Tolfenamic Acid_m4[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M4 |
Tolfenamic Acid_M4 |
UidB |
Glucuronate transport in via proton symport N-(2-Methyl-3- Chloro-4-Hydroxyphenyl)-Anthranilic Acid |
Tolfenamic Acid_m4[e] + h[e] -> Tolfenamic Acid_m4[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M4 |
Tolfenamic Acid_M4 |
UidB |
Glucuronate transport in via proton symport N-(2-Methyl-3- Chloro-4-Hydroxyphenyl)-Anthranilic Acid, periplasmatic |
h[p] + Tolfenamic Acid_m4[p] -> h[c] + Tolfenamic Acid_m4[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M4 |
Tolfenamic Acid_M4 |
n.a. |
N-(2-Methyl-3- Chloro-4-Hydroxyphenyl)-Anthranilic Acid diffusion extracellular to periplasm |
Tolfenamic Acid_m4[e] <=> Tolfenamic Acid_m4[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M5 |
Tolfenamic Acid_1B |
UidAc |
N-(2-Methyl-3-Chloro-5-Hydroxyphenyl)-Anthranilic Acid beta-glucuronidase |
Tolfenamic Acid_m5[c] + h2o[c] -> Tolfenamic Acid_1b[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M5 |
Tolfenamic Acid_1B |
UidAe |
N-(2-Methyl-3-Chloro-5-Hydroxyphenyl)-Anthranilic Acid beta-glucuronidase extracellular |
Tolfenamic Acid_m5[e] + h2o[e] -> Tolfenamic Acid_1b[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M5 |
Tolfenamic Acid_1B |
UidAe |
N-(2-Methyl-3-Chloro-5-Hydroxyphenyl)-Anthranilic Acid beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Tolfenamic Acid_m5[p] -> glcur[p] + h[p] + Tolfenamic Acid_1b[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_M5A |
Tolfenamic Acid_1B |
UidAc |
Tolfenamic Acid M5A beta-glucuronidase |
Tolfenamic Acid_m5a[c] + h2o[c] -> Tolfenamic Acid_1b[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_M5A |
Tolfenamic Acid_1B |
UidAe |
Tolfenamic Acid M5A beta-glucuronidase extracellular |
Tolfenamic Acid_m5a[e] + h2o[e] -> Tolfenamic Acid_1b[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_M5A |
Tolfenamic Acid_1B |
UidAe |
Tolfenamic Acid M5A beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Tolfenamic Acid_m5a[p] -> glcur[p] + Tolfenamic Acid_1b[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_M5A |
Tolfenamic Acid_M5A |
UidABC |
Predicted glucuronide ABC transporter Tolfenamic Acid M5A |
atp[c] + Tolfenamic Acid_m5a[e] + h2o[c] -> adp[c] + Tolfenamic Acid_m5a[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M5 |
Tolfenamic Acid_M5 |
UidABC |
Predicted glucuronide ABC transporter N-(2-Methyl-3-Chloro-5-Hydroxyphenyl)-Anthranilic Acid |
atp[c] + Tolfenamic Acid_m5[e] + h2o[c] -> adp[c] + Tolfenamic Acid_m5[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_M5A |
Tolfenamic Acid_M5A |
UidP |
Transport of D-Glucuronate Tolfenamic Acid M5A |
Tolfenamic Acid_m5a[e] -> Tolfenamic Acid_m5a[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_M5A |
Tolfenamic Acid_M5A |
UidB |
Glucuronate transport in via proton symport Tolfenamic Acid M5A |
Tolfenamic Acid_m5a[e] + h[e] -> Tolfenamic Acid_m5a[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_M5A |
Tolfenamic Acid_M5A |
UidB |
Glucuronate transport in via proton symport Tolfenamic Acid M5A, periplasmatic |
h[p] + Tolfenamic Acid_m5a[p] -> h[c] + Tolfenamic Acid_m5a[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_M5A |
Tolfenamic Acid_M5A |
n.a. |
Tolfenamic Acid M5A diffusion extracellular to periplasm |
Tolfenamic Acid_m5a[e] <=> Tolfenamic Acid_m5a[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_M5B |
Tolfenamic Acid_M5 |
UidAc |
Tolfenamic Acid M5B beta-glucuronidase |
Tolfenamic Acid_m5b[c] + h2o[c] -> Tolfenamic Acid_m5[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_M5B |
Tolfenamic Acid_M5 |
UidAe |
Tolfenamic Acid M5B beta-glucuronidase extracellular |
Tolfenamic Acid_m5b[e] + h2o[e] -> Tolfenamic Acid_m5[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_M5B |
Tolfenamic Acid_M5 |
UidAe |
Tolfenamic Acid M5B beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Tolfenamic Acid_m5b[p] -> glcur[p] + Tolfenamic Acid_m5[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_M5B |
Tolfenamic Acid_M5B |
UidABC |
Predicted glucuronide ABC transporter Tolfenamic Acid M5B |
atp[c] + Tolfenamic Acid_m5b[e] + h2o[c] -> adp[c] + Tolfenamic Acid_m5b[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_M5B |
Tolfenamic Acid_M5B |
UidP |
Transport of D-Glucuronate Tolfenamic Acid M5B |
Tolfenamic Acid_m5b[e] -> Tolfenamic Acid_m5b[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_M5B |
Tolfenamic Acid_M5B |
UidB |
Glucuronate transport in via proton symport Tolfenamic Acid M5B |
Tolfenamic Acid_m5b[e] + h[e] -> Tolfenamic Acid_m5b[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_M5B |
Tolfenamic Acid_M5B |
UidB |
Glucuronate transport in via proton symport Tolfenamic Acid M5B, periplasmatic |
h[p] + Tolfenamic Acid_m5b[p] -> h[c] + Tolfenamic Acid_m5b[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid_M5B |
Tolfenamic Acid_M5B |
n.a. |
Tolfenamic Acid M5B diffusion extracellular to periplasm |
Tolfenamic Acid_m5b[e] <=> Tolfenamic Acid_m5b[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M5 |
Tolfenamic Acid_M5 |
UidP |
Transport of D-Glucuronate N-(2-Methyl-3-Chloro-5-Hydroxyphenyl)-Anthranilic Acid |
Tolfenamic Acid_m5[e] -> Tolfenamic Acid_m5[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M5 |
Tolfenamic Acid_M5 |
UidB |
Glucuronate transport in via proton symport N-(2-Methyl-3-Chloro-5-Hydroxyphenyl)-Anthranilic Acid |
Tolfenamic Acid_m5[e] + h[e] -> Tolfenamic Acid_m5[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M5 |
Tolfenamic Acid_M5 |
UidB |
Glucuronate transport in via proton symport N-(2-Methyl-3-Chloro-5-Hydroxyphenyl)-Anthranilic Acid, periplasmatic |
h[p] + Tolfenamic Acid_m5[p] -> h[c] + Tolfenamic Acid_m5[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M5 |
Tolfenamic Acid_M5 |
n.a. |
beta-glucuronidase reaction product export N-(2-Methyl-3-Chloro-5-Hydroxyphenyl)-Anthranilic Acid |
Tolfenamic Acid_m5[c] -> Tolfenamic Acid_m5[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M5 |
Tolfenamic Acid_M5 |
n.a. |
beta-glucuronidase reaction product export N-(2-Methyl-3-Chloro-5-Hydroxyphenyl)-Anthranilic Acid, periplasmatic |
Tolfenamic Acid_m5[c] -> Tolfenamic Acid_m5[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M5 |
Tolfenamic Acid_M5 |
n.a. |
N-(2-Methyl-3-Chloro-5-Hydroxyphenyl)-Anthranilic Acid diffusion extracellular to periplasm |
Tolfenamic Acid_m5[e] <=> Tolfenamic Acid_m5[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M6 |
Tolfenamic Acid_4 |
UidAc |
N-(2-Carboxy-3-Chlorophenyl)-Anthranilic Acid beta-glucuronidase |
Tolfenamic Acid_m6[c] + h2o[c] -> Tolfenamic Acid_4[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M6 |
Tolfenamic Acid_4 |
UidAe |
N-(2-Carboxy-3-Chlorophenyl)-Anthranilic Acid beta-glucuronidase extracellular |
Tolfenamic Acid_m6[e] + h2o[e] -> Tolfenamic Acid_4[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M6 |
Tolfenamic Acid_4 |
UidAe |
N-(2-Carboxy-3-Chlorophenyl)-Anthranilic Acid beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Tolfenamic Acid_m6[p] -> glcur[p] + h[p] + Tolfenamic Acid_4[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M6 |
Tolfenamic Acid_M6 |
UidABC |
Predicted glucuronide ABC transporter N-(2-Carboxy-3-Chlorophenyl)-Anthranilic Acid |
atp[c] + Tolfenamic Acid_m6[e] + h2o[c] -> adp[c] + Tolfenamic Acid_m6[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M6 |
Tolfenamic Acid_M6 |
UidP |
Transport of D-Glucuronate N-(2-Carboxy-3-Chlorophenyl)-Anthranilic Acid |
Tolfenamic Acid_m6[e] -> Tolfenamic Acid_m6[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M6 |
Tolfenamic Acid_M6 |
UidB |
Glucuronate transport in via proton symport N-(2-Carboxy-3-Chlorophenyl)-Anthranilic Acid |
Tolfenamic Acid_m6[e] + h[e] -> Tolfenamic Acid_m6[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M6 |
Tolfenamic Acid_M6 |
UidB |
Glucuronate transport in via proton symport N-(2-Carboxy-3-Chlorophenyl)-Anthranilic Acid, periplasmatic |
h[p] + Tolfenamic Acid_m6[p] -> h[c] + Tolfenamic Acid_m6[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M6 |
Tolfenamic Acid_M6 |
n.a. |
N-(2-Carboxy-3-Chlorophenyl)-Anthranilic Acid diffusion extracellular to periplasm |
Tolfenamic Acid_m6[e] <=> Tolfenamic Acid_m6[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M9 |
Tolfenamic Acid_1X |
UidAc |
N-(2-Methyl-3-Chloro-4-Metoxyphenyl)-Anthranilic Acid beta-glucuronidase |
Tolfenamic Acid_m9[c] + h2o[c] -> Tolfenamic Acid_1x[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M9 |
Tolfenamic Acid_1X |
UidAe |
N-(2-Methyl-3-Chloro-4-Metoxyphenyl)-Anthranilic Acid beta-glucuronidase extracellular |
Tolfenamic Acid_m9[e] + h2o[e] -> Tolfenamic Acid_1x[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M9 |
Tolfenamic Acid_1X |
UidAe |
N-(2-Methyl-3-Chloro-4-Metoxyphenyl)-Anthranilic Acid beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Tolfenamic Acid_m9[p] -> glcur[p] + h[p] + Tolfenamic Acid_1x[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M9 |
Tolfenamic Acid_M9 |
UidABC |
Predicted glucuronide ABC transporter N-(2-Methyl-3-Chloro-4-Metoxyphenyl)-Anthranilic Acid |
atp[c] + Tolfenamic Acid_m9[e] + h2o[c] -> adp[c] + Tolfenamic Acid_m9[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M9 |
Tolfenamic Acid_M9 |
UidP |
Transport of D-Glucuronate N-(2-Methyl-3-Chloro-4-Metoxyphenyl)-Anthranilic Acid |
Tolfenamic Acid_m9[e] -> Tolfenamic Acid_m9[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M9 |
Tolfenamic Acid_M9 |
UidB |
Glucuronate transport in via proton symport N-(2-Methyl-3-Chloro-4-Metoxyphenyl)-Anthranilic Acid |
Tolfenamic Acid_m9[e] + h[e] -> Tolfenamic Acid_m9[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M9 |
Tolfenamic Acid_M9 |
UidB |
Glucuronate transport in via proton symport N-(2-Methyl-3-Chloro-4-Metoxyphenyl)-Anthranilic Acid, periplasmatic |
h[p] + Tolfenamic Acid_m9[p] -> h[c] + Tolfenamic Acid_m9[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB04166 |
Tolfenamic Acid_M9 |
Tolfenamic Acid_M9 |
n.a. |
N-(2-Methyl-3-Chloro-4-Metoxyphenyl)-Anthranilic Acid diffusion extracellular to periplasm |
Tolfenamic Acid_m9[e] <=> Tolfenamic Acid_m9[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid |
Tolfenamic Acid |
n.a. |
beta-glucuronidase reaction product export Tolfenamic Acid |
Tolfenamic Acid[c] -> Tolfenamic Acid[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid |
Tolfenamic Acid |
n.a. |
beta-glucuronidase reaction product export Tolfenamic Acid, periplasmatic |
Tolfenamic Acid[c] -> Tolfenamic Acid[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB09216 |
Tolfenamic Acid |
Tolfenamic Acid |
n.a. |
Tolfenamic Acid diffusion extracellular to periplasm |
Tolfenamic Acid[e] <=> Tolfenamic Acid[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00966 |
Telmisartan_Glc |
Telmisartan |
UidAc |
Telmisartan Glucuronide beta-glucuronidase |
Telmisartan_glc[c] + h2o[c] -> Telmisartan[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00966 |
Telmisartan_Glc |
Telmisartan |
UidAe |
Telmisartan Glucuronide beta-glucuronidase extracellular |
Telmisartan_glc[e] + h2o[e] -> Telmisartan[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00966 |
Telmisartan_Glc |
Telmisartan |
UidAe |
Telmisartan Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Telmisartan_glc[p] -> glcur[p] + h[p] + Telmisartan[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00966 |
Telmisartan_Glc |
Telmisartan_Glc |
UidABC |
Predicted glucuronide ABC transporter Telmisartan Glucuronide |
atp[c] + Telmisartan_glc[e] + h2o[c] -> adp[c] + Telmisartan_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00966 |
Telmisartan_Glc |
Telmisartan_Glc |
UidP |
Transport of D-Glucuronate Telmisartan Glucuronide |
Telmisartan_glc[e] -> Telmisartan_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00966 |
Telmisartan_Glc |
Telmisartan_Glc |
UidB |
Glucuronate transport in via proton symport Telmisartan Glucuronide |
Telmisartan_glc[e] + h[e] -> Telmisartan_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00966 |
Telmisartan_Glc |
Telmisartan_Glc |
UidB |
Glucuronate transport in via proton symport Telmisartan Glucuronide, periplasmatic |
h[p] + Telmisartan_glc[p] -> h[c] + Telmisartan_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00966 |
Telmisartan_Glc |
Telmisartan_Glc |
n.a. |
Telmisartan Glucuronide diffusion extracellular to periplasm |
Telmisartan_glc[e] <=> Telmisartan_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00966 |
Telmisartan |
Telmisartan |
n.a. |
beta-glucuronidase reaction product export Telmisartan |
Telmisartan[c] -> Telmisartan[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00966 |
Telmisartan |
Telmisartan |
n.a. |
beta-glucuronidase reaction product export Telmisartan, periplasmatic |
Telmisartan[c] -> Telmisartan[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00966 |
Telmisartan |
Telmisartan |
n.a. |
Telmisartan diffusion extracellular to periplasm |
Telmisartan[e] <=> Telmisartan[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Tmacetaminophen |
Tmacetaminophen |
n.a. |
beta-glucuronidase reaction product export thiomethyl-conjugate-acetaminophen |
tmAcetaminophen[c] -> tmAcetaminophen[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00446 |
Nchloramphenicol |
Nchloramphenicol |
n.a. |
Nitrosochloramphenicol transport, reversible, hypothetical reaction, periplasmatic |
nChloramphenicol[p] <=> nChloramphenicol[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB01595 |
Nitrazepam, Benzalin, Neozepam |
Nitrazepam, Benzalin, Neozepam |
n.a. |
Nitrazepam transport, reversible, hypothetical reaction, periplasmatic |
Nitrazepam, Benzalin, Neozepam[p] <=> Nitrazepam, Benzalin, Neozepam[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Ac_Glc |
Tolcapone?_Ac |
UidAc |
Tolcapone N-Acetyl Amino Glucuronide beta-glucuronidase |
Tolcapone?_ac_glc[c] + h2o[c] -> Tolcapone?_ac[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Ac_Glc |
Tolcapone?_Ac |
UidAe |
Tolcapone N-Acetyl Amino Glucuronide beta-glucuronidase extracellular |
Tolcapone?_ac_glc[e] + h2o[e] -> Tolcapone?_ac[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Ac_Glc |
Tolcapone?_Ac |
UidAe |
Tolcapone N-Acetyl Amino Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Tolcapone?_ac_glc[p] -> glcur[p] + Tolcapone?_ac[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Ac_Glc |
Tolcapone?_Ac_Glc |
UidABC |
Predicted glucuronide ABC transporter Tolcapone N-Acetyl Amino Glucuronide |
atp[c] + Tolcapone?_ac_glc[e] + h2o[c] -> adp[c] + Tolcapone?_ac_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Ac_Glc |
Tolcapone?_Ac_Glc |
UidP |
Transport of D-Glucuronate Tolcapone N-Acetyl Amino Glucuronide |
Tolcapone?_ac_glc[e] -> Tolcapone?_ac_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Ac_Glc |
Tolcapone?_Ac_Glc |
UidB |
Glucuronate transport in via proton symport Tolcapone N-Acetyl Amino Glucuronide |
Tolcapone?_ac_glc[e] + h[e] -> Tolcapone?_ac_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Ac_Glc |
Tolcapone?_Ac_Glc |
UidB |
Glucuronate transport in via proton symport Tolcapone N-Acetyl Amino Glucuronide, periplasmatic |
h[p] + Tolcapone?_ac_glc[p] -> h[c] + Tolcapone?_ac_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Ac_Glc |
Tolcapone?_Ac_Glc |
n.a. |
Tolcapone N-Acetyl Amino Glucuronide diffusion extracellular to periplasm |
Tolcapone?_ac_glc[e] <=> Tolcapone?_ac_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Ac |
Tolcapone?_Ac |
n.a. |
beta-glucuronidase reaction product export Tolcapone N-Acetyl Amino Metabolite |
Tolcapone?_ac[c] -> Tolcapone?_ac[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Ac |
Tolcapone?_Ac |
n.a. |
beta-glucuronidase reaction product export Tolcapone N-Acetyl Amino Metabolite, periplasmatic |
Tolcapone?_ac[c] -> Tolcapone?_ac[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Ac |
Tolcapone?_Ac |
n.a. |
Tolcapone N-Acetyl Amino Metabolite diffusion extracellular to periplasm |
Tolcapone?_ac[e] <=> Tolcapone?_ac[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Am_Glc |
Tolcapone?_Am |
UidAc |
Tolcapone Amine Glucuronide beta-glucuronidase |
Tolcapone?_am_glc[c] + h2o[c] -> Tolcapone?_am[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Am_Glc |
Tolcapone?_Am |
UidAe |
Tolcapone Amine Glucuronide beta-glucuronidase extracellular |
Tolcapone?_am_glc[e] + h2o[e] -> Tolcapone?_am[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Am_Glc |
Tolcapone?_Am |
UidAe |
Tolcapone Amine Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Tolcapone?_am_glc[p] -> glcur[p] + Tolcapone?_am[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Am_Glc |
Tolcapone?_Am_Glc |
UidABC |
Predicted glucuronide ABC transporter Tolcapone Amine Glucuronide |
atp[c] + Tolcapone?_am_glc[e] + h2o[c] -> adp[c] + Tolcapone?_am_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Am_Glc |
Tolcapone?_Am_Glc |
UidP |
Transport of D-Glucuronate Tolcapone Amine Glucuronide |
Tolcapone?_am_glc[e] -> Tolcapone?_am_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Am_Glc |
Tolcapone?_Am_Glc |
UidB |
Glucuronate transport in via proton symport Tolcapone Amine Glucuronide |
Tolcapone?_am_glc[e] + h[e] -> Tolcapone?_am_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Am_Glc |
Tolcapone?_Am_Glc |
UidB |
Glucuronate transport in via proton symport Tolcapone Amine Glucuronide, periplasmatic |
h[p] + Tolcapone?_am_glc[p] -> h[c] + Tolcapone?_am_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Am_Glc |
Tolcapone?_Am_Glc |
n.a. |
Tolcapone Amine Glucuronide diffusion extracellular to periplasm |
Tolcapone?_am_glc[e] <=> Tolcapone?_am_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Am |
Tolcapone?_Am |
n.a. |
beta-glucuronidase reaction product export Tolcapone Amine Derivative |
Tolcapone?_am[c] -> Tolcapone?_am[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Am |
Tolcapone?_Am |
n.a. |
beta-glucuronidase reaction product export Tolcapone Amine Derivative, periplasmatic |
Tolcapone?_am[c] -> Tolcapone?_am[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Am |
Tolcapone?_Am |
n.a. |
Tolcapone Amine Derivative diffusion extracellular to periplasm |
Tolcapone?_am[e] <=> Tolcapone?_am[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Glc |
Tolcapone? |
UidAc |
Tolcapone 3-Beta-D-Glucuronide beta-glucuronidase |
Tolcapone?_glc[c] + h2o[c] -> Tolcapone?[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Glc |
Tolcapone? |
UidAe |
Tolcapone 3-Beta-D-Glucuronide beta-glucuronidase extracellular |
Tolcapone?_glc[e] + h2o[e] -> Tolcapone?[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Glc |
Tolcapone? |
UidAe |
Tolcapone 3-Beta-D-Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Tolcapone?_glc[p] -> glcur[p] + Tolcapone?[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Glc |
Tolcapone?_Glc |
UidABC |
Predicted glucuronide ABC transporter Tolcapone 3-Beta-D-Glucuronide |
atp[c] + Tolcapone?_glc[e] + h2o[c] -> adp[c] + Tolcapone?_glc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Glc |
Tolcapone?_Glc |
UidP |
Transport of D-Glucuronate Tolcapone 3-Beta-D-Glucuronide |
Tolcapone?_glc[e] -> Tolcapone?_glc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Glc |
Tolcapone?_Glc |
UidB |
Glucuronate transport in via proton symport Tolcapone 3-Beta-D-Glucuronide |
Tolcapone?_glc[e] + h[e] -> Tolcapone?_glc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Glc |
Tolcapone?_Glc |
UidB |
Glucuronate transport in via proton symport Tolcapone 3-Beta-D-Glucuronide, periplasmatic |
h[p] + Tolcapone?_glc[p] -> h[c] + Tolcapone?_glc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone?_Glc |
Tolcapone?_Glc |
n.a. |
Tolcapone 3-Beta-D-Glucuronide diffusion extracellular to periplasm |
Tolcapone?_glc[e] <=> Tolcapone?_glc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone? |
Tolcapone? |
n.a. |
beta-glucuronidase reaction product export Tolcapone? |
Tolcapone?[c] -> Tolcapone?[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone? |
Tolcapone? |
n.a. |
beta-glucuronidase reaction product export Tolcapone?-??, periplasmatic |
Tolcapone?[c] -> Tolcapone?[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00323 |
Tolcapone? |
Tolcapone? |
n.a. |
Tolcapone?-?? diffusion extracellular to periplasm |
Tolcapone?[e] <=> Tolcapone?[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB12449 |
Tempol 1-O-Glucuronide And 4-O-Glucoside |
Tempol 4-O-Glucoside |
UidAc |
Tempol 1-O-Glucuronide And 4-O-Glucoside beta-glucuronidase |
Tempol 1-O-Glucuronide And 4-O-Glucoside[c] + h2o[c] -> Tempol 4-O-Glucoside[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB12449 |
Tempol 1-O-Glucuronide And 4-O-Glucoside |
Tempol 4-O-Glucoside |
UidAe |
Tempol 1-O-Glucuronide And 4-O-Glucoside beta-glucuronidase extracellular |
Tempol 1-O-Glucuronide And 4-O-Glucoside[e] + h2o[e] -> Tempol 4-O-Glucoside[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB12449 |
Tempol 1-O-Glucuronide And 4-O-Glucoside |
Tempol 4-O-Glucoside |
UidAe |
Tempol 1-O-Glucuronide And 4-O-Glucoside beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Tempol 1-O-Glucuronide And 4-O-Glucoside[p] -> glcur[p] + h[p] + Tempol 4-O-Glucoside[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB12449 |
Tempol 1-O-Glucuronide And 4-O-Glucoside |
Tempol 1-O-Glucuronide And 4-O-Glucoside |
UidABC |
Predicted glucuronide ABC transporter Tempol 1-O-Glucuronide And 4-O-Glucoside |
atp[c] + Tempol 1-O-Glucuronide And 4-O-Glucoside[e] + h2o[c] -> adp[c] + Tempol 1-O-Glucuronide And 4-O-Glucoside[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB12449 |
Tempol 1-O-Glucuronide And 4-O-Glucoside |
Tempol 1-O-Glucuronide And 4-O-Glucoside |
UidP |
Transport of D-Glucuronate Tempol 1-O-Glucuronide And 4-O-Glucoside |
Tempol 1-O-Glucuronide And 4-O-Glucoside[e] -> Tempol 1-O-Glucuronide And 4-O-Glucoside[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB12449 |
Tempol 1-O-Glucuronide And 4-O-Glucoside |
Tempol 1-O-Glucuronide And 4-O-Glucoside |
UidB |
Glucuronate transport in via proton symport Tempol 1-O-Glucuronide And 4-O-Glucoside |
Tempol 1-O-Glucuronide And 4-O-Glucoside[e] + h[e] -> Tempol 1-O-Glucuronide And 4-O-Glucoside[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB12449 |
Tempol 1-O-Glucuronide And 4-O-Glucoside |
Tempol 1-O-Glucuronide And 4-O-Glucoside |
UidB |
Glucuronate transport in via proton symport Tempol 1-O-Glucuronide And 4-O-Glucoside, periplasmatic |
h[p] + Tempol 1-O-Glucuronide And 4-O-Glucoside[p] -> h[c] + Tempol 1-O-Glucuronide And 4-O-Glucoside[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB12449 |
Tempol 1-O-Glucuronide And 4-O-Glucoside |
Tempol 1-O-Glucuronide And 4-O-Glucoside |
n.a. |
Tempol 1-O-Glucuronide And 4-O-Glucoside diffusion extracellular to periplasm |
Tempol 1-O-Glucuronide And 4-O-Glucoside[e] <=> Tempol 1-O-Glucuronide And 4-O-Glucoside[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB12449 |
Tempol 4-O-Glucosidelc |
Tempol Hydroxylamine |
UidAc |
Tempol 4-O-Glucuronide beta-glucuronidase |
Tempol 4-O-Glucosidelc[c] + h2o[c] -> Tempol Hydroxylamine[c] + glcur[c] + h[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB12449 |
Tempol 4-O-Glucosidelc |
Tempol Hydroxylamine |
UidAe |
Tempol 4-O-Glucuronide beta-glucuronidase extracellular |
Tempol 4-O-Glucosidelc[e] + h2o[e] -> Tempol Hydroxylamine[e] + glcur[e] + h[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB12449 |
Tempol 4-O-Glucosidelc |
Tempol Hydroxylamine |
UidAe |
Tempol 4-O-Glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + Tempol 4-O-Glucosidelc[p] -> glcur[p] + h[p] + Tempol Hydroxylamine[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB12449 |
Tempol 4-O-Glucosidelc |
Tempol 4-O-Glucosidelc |
UidABC |
Predicted glucuronide ABC transporter Tempol 4-O-Glucuronide |
atp[c] + Tempol 4-O-Glucosidelc[e] + h2o[c] -> adp[c] + Tempol 4-O-Glucosidelc[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB12449 |
Tempol 4-O-Glucosidelc |
Tempol 4-O-Glucosidelc |
UidP |
Transport of D-Glucuronate Tempol 4-O-Glucuronide |
Tempol 4-O-Glucosidelc[e] -> Tempol 4-O-Glucosidelc[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB12449 |
Tempol 4-O-Glucosidelc |
Tempol 4-O-Glucosidelc |
UidB |
Glucuronate transport in via proton symport Tempol 4-O-Glucuronide |
Tempol 4-O-Glucosidelc[e] + h[e] -> Tempol 4-O-Glucosidelc[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB12449 |
Tempol 4-O-Glucosidelc |
Tempol 4-O-Glucosidelc |
UidB |
Glucuronate transport in via proton symport Tempol 4-O-Glucuronide, periplasmatic |
h[p] + Tempol 4-O-Glucosidelc[p] -> h[c] + Tempol 4-O-Glucosidelc[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB12449 |
Tempol 4-O-Glucosidelc |
Tempol 4-O-Glucosidelc |
n.a. |
Tempol 4-O-Glucuronide diffusion extracellular to periplasm |
Tempol 4-O-Glucosidelc[e] <=> Tempol 4-O-Glucosidelc[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB12449 |
Tempol 4-O-Glucoside |
Tempol 4-O-Glucoside |
n.a. |
beta-glucuronidase reaction product export Tempol 4-O-Glucoside |
Tempol 4-O-Glucoside[c] -> Tempol 4-O-Glucoside[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB12449 |
Tempol 4-O-Glucoside |
Tempol 4-O-Glucoside |
n.a. |
beta-glucuronidase reaction product export Tempol 4-O-Glucoside, periplasmatic |
Tempol 4-O-Glucoside[c] -> Tempol 4-O-Glucoside[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB12449 |
Tempol 4-O-Glucoside |
Tempol 4-O-Glucoside |
n.a. |
Tempol 4-O-Glucoside diffusion extracellular to periplasm |
Tempol 4-O-Glucoside[e] <=> Tempol 4-O-Glucoside[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB12449 |
Tempol Hydroxylamine |
Tempol Hydroxylamine |
n.a. |
beta-glucuronidase reaction product export Tempol Hydroxylamine |
Tempol Hydroxylamine[c] -> Tempol Hydroxylamine[e] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Thiomethyl-Sulphoxide-Acetaminophen-Glucuronide |
Thsacetaminophen |
UidAc |
thiomethyl-sulphoxide-acetaminophen-glucuronide beta-glucuronidase |
thiomethyl-sulphoxide-acetaminophen-glucuronide[c] + h2o[c] -> thsAcetaminophen[c] + glcur[c] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00316 |
Thiomethyl-Sulphoxide-Acetaminophen-Glucuronide |
Thsacetaminophen |
UidAe |
thiomethyl-sulphoxide-acetaminophen-glucuronide beta-glucuronidase extracellular |
thiomethyl-sulphoxide-acetaminophen-glucuronide[e] + h2o[e] -> thsAcetaminophen[e] + glcur[e] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00316 |
Thiomethyl-Sulphoxide-Acetaminophen-Glucuronide |
Thsacetaminophen |
UidAe |
thiomethyl-sulphoxide-acetaminophen-glucuronide beta-glucuronidase extracellular, periplasmatic |
h2o[p] + thiomethyl-sulphoxide-acetaminophen-glucuronide[p] -> glcur[p] + thsAcetaminophen[p] |
Drug metabolism |
Metabolism |
Experimental Subsystems |
Drug metabolism |
n.a. |
PMID: 36658342 |
| DB00316 |
Thiomethyl-Sulphoxide-Acetaminophen-Glucuronide |
Thiomethyl-Sulphoxide-Acetaminophen-Glucuronide |
UidABC |
Predicted glucuronide ABC transporter thiomethyl-sulphoxide-acetaminophen-glucuronide |
atp[c] + thiomethyl-sulphoxide-acetaminophen-glucuronide[e] + h2o[c] -> adp[c] + thiomethyl-sulphoxide-acetaminophen-glucuronide[c] + h[c] + pi[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Thiomethyl-Sulphoxide-Acetaminophen-Glucuronide |
Thiomethyl-Sulphoxide-Acetaminophen-Glucuronide |
UidP |
Transport of D-Glucuronate thiomethyl-sulphoxide-acetaminophen-glucuronide |
thiomethyl-sulphoxide-acetaminophen-glucuronide[e] -> thiomethyl-sulphoxide-acetaminophen-glucuronide[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Thiomethyl-Sulphoxide-Acetaminophen-Glucuronide |
Thiomethyl-Sulphoxide-Acetaminophen-Glucuronide |
UidB |
Glucuronate transport in via proton symport thiomethyl-sulphoxide-acetaminophen-glucuronide |
thiomethyl-sulphoxide-acetaminophen-glucuronide[e] + h[e] -> thiomethyl-sulphoxide-acetaminophen-glucuronide[c] + h[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Thiomethyl-Sulphoxide-Acetaminophen-Glucuronide |
Thiomethyl-Sulphoxide-Acetaminophen-Glucuronide |
UidB |
Glucuronate transport in via proton symport thiomethyl-sulphoxide-acetaminophen-glucuronide, periplasmatic |
h[p] + thiomethyl-sulphoxide-acetaminophen-glucuronide[p] -> h[c] + thiomethyl-sulphoxide-acetaminophen-glucuronide[c] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB00316 |
Thiomethyl-Sulphoxide-Acetaminophen-Glucuronide |
Thiomethyl-Sulphoxide-Acetaminophen-Glucuronide |
n.a. |
thiomethyl-sulphoxide-acetaminophen-glucuronide diffusion extracellular to periplasm |
thiomethyl-sulphoxide-acetaminophen-glucuronide[e] <=> thiomethyl-sulphoxide-acetaminophen-glucuronide[p] |
Transport, periplasmatic |
Transport |
Transport, periplasmatic |
n.a. |
n.a. |
PMID: 36658342 |
| DB08841 |
Tym |
Tym |
Tdc |
Tyramine transport in via proton symport reversible |
h[e] + tym[e] <=> h[c] + tym[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |
| DB00135 |
Tyr_L |
Tym |
Tdc |
L-Tyrosine Carboxy-Lyase |
h[c] + tyr_L[c] -> co2[c] + tym[c] |
Tyrosine metabolism |
Metabolism |
Amino Acids and Derivatives |
Aromatic amino acids and derivatives |
Tyrosine metabolism |
PMID: 30659181 |
| DB00135 |
Tyr_L |
Tyr_L |
Tdc |
L-tyrosine reversible transport via proton symport |
h[e] + tyr_L[e] <=> h[c] + tyr_L[c] |
Transport, extracellular |
Transport |
Transport, extracellular |
n.a. |
n.a. |
PMID: 36658342 |