GCF_000023125.1_ASM2312v1_genomic - 5 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NC_013037.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	arylpolyene	2,410,428	2,455,879	flexirubin	Polyketide	27%
Region 2	T3PKS,terpene	2,461,840	2,503,810	carotenoid	Terpene	28%
Region 3	RiPP-like	5,929,283	5,941,499
Region 4	RRE-containing	6,079,175	6,099,441
Region 5	resorcinol,arylpolyene	6,938,406	6,967,790	flexirubin	Polyketide	13%

NC_013037.1 - Region 1 - arylpolyene

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Location: 2,410,428 - 2,455,879 nt. (total: 45,452 nt) Show pHMM detection rules used

arylpolyene: (APE_KS1 or APE_KS2)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000231.1	0.24	Polyketide	griseusin	Streptomyces griseus
BGC0000248.1	0.21	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0000272.1	0.21	Polyketide	spore pigment	Streptomyces collinus
BGC0000194.1	0.20	Polyketide	actinorhodin	Streptomyces coelicolor A3(2)
BGC0000219.1	0.20	Polyketide, Saccharide	elloramycin	Streptomyces olivaceus
BGC0000261.1	0.20	Polyketide	R1128	Streptomyces sp. R1128
BGC0000221.1	0.20	Polyketide	erdacin	uncultured soil bacterium V167
BGC0000237.1	0.19	Polyketide	lactonamycin Z	Streptomyces sanglieri
BGC0002000.1	0.19	Polyketide	setomimycin	Streptomyces aurantiacus JA 4570
BGC0000275.1	0.18	Polyketide	tetracenomycin C	Streptomyces glaucescens

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000231.1	0.57	Polyketide	griseusin	Streptomyces griseus
BGC0000248.1	0.54	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0000272.1	0.54	Polyketide	spore pigment	Streptomyces collinus
BGC0000194.1	0.53	Polyketide	actinorhodin	Streptomyces coelicolor A3(2)
BGC0000219.1	0.53	Polyketide, Saccharide	elloramycin	Streptomyces olivaceus
BGC0000261.1	0.53	Polyketide	R1128	Streptomyces sp. R1128
BGC0000221.1	0.52	Polyketide	erdacin	uncultured soil bacterium V167
BGC0000237.1	0.51	Polyketide	lactonamycin Z	Streptomyces sanglieri
BGC0002000.1	0.51	Polyketide	setomimycin	Streptomyces aurantiacus JA 4570
BGC0000275.1	0.50	Polyketide	tetracenomycin C	Streptomyces glaucescens

Similar known gene clusters

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NC_013037.1 - Region 2 - T3PKS,terpene

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Location: 2,461,840 - 2,503,810 nt. (total: 41,971 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001938.1	0.67	Polyketide	entotheonella	Candidatus Entotheonella serta
BGC0001962.1	0.66	Polyketide	hierridin B, hierridin C	Cyanobium sp. LEGE 06113
BGC0000648.1	0.64	Terpene	carotenoid	Myxococcus xanthus
BGC0001905.1	0.63	Polyketide	violapyrone B	Streptomyces somaliensis
BGC0000647.1	0.62	Terpene	carotenoid	Rhodobacter sphaeroides
BGC0000645.1	0.59	Terpene	carotenoid	Halobacillus halophilus DSM 2266
BGC0000650.1	0.58	Terpene	carotenoid	Algoriphagus sp. KK10202C
BGC0000630.1	0.49	Terpene	(2R,3S,3'S)-2-hydroxyastaxanthin	Paracoccus haeundaensis
BGC0000656.1	0.47	Terpene	zeaxanthin	Xanthobacter autotrophicus Py2
BGC0001831.1	0.46	Polyketide	alkylpyrone-407, alkylpyrone-393	Myxococcus xanthus DK 1622

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001938.1	0.67	Polyketide	entotheonella	Candidatus Entotheonella serta
BGC0001962.1	0.66	Polyketide	hierridin B, hierridin C	Cyanobium sp. LEGE 06113
BGC0000648.1	0.65	Terpene	carotenoid	Myxococcus xanthus
BGC0001905.1	0.65	Polyketide	violapyrone B	Streptomyces somaliensis
BGC0000645.1	0.64	Terpene	carotenoid	Halobacillus halophilus DSM 2266
BGC0000647.1	0.64	Terpene	carotenoid	Rhodobacter sphaeroides
BGC0000650.1	0.63	Terpene	carotenoid	Algoriphagus sp. KK10202C
BGC0000630.1	0.58	Terpene	(2R,3S,3'S)-2-hydroxyastaxanthin	Paracoccus haeundaensis
BGC0000656.1	0.57	Terpene	zeaxanthin	Xanthobacter autotrophicus Py2
BGC0001831.1	0.56	Polyketide	alkylpyrone-407, alkylpyrone-393	Myxococcus xanthus DK 1622

Similar known gene clusters

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NC_013037.1 - Region 3 - RiPP-like

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Location: 5,929,283 - 5,941,499 nt. (total: 12,217 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000554.1	0.20	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0001861.1	0.20	RiPP	bacillicin BAG2O	Bacillus cereus BAG2O-1
BGC0000617.1	0.19	RiPP	coagulin	Bacillus coagulans
BGC0000500.1	0.19	RiPP	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0000624.1	0.16	RiPP	salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide	Lactobacillus salivarius
BGC0001210.1	0.15	RiPP	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0001928.1	0.15	Other	(2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid	Streptomyces sp. MA37
BGC0000626.1	0.15	RiPP	thuricin	Bacillus thuringiensis
BGC0001551.1	0.15	RiPP	citrulassin E	Streptomyces glaucescens
BGC0001639.1	0.15	RiPP	klebsidin	Klebsiella pneumoniae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000554.1	0.53	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0001861.1	0.53	RiPP	bacillicin BAG2O	Bacillus cereus BAG2O-1
BGC0000617.1	0.51	RiPP	coagulin	Bacillus coagulans
BGC0000500.1	0.51	RiPP	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0000624.1	0.47	RiPP	salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide	Lactobacillus salivarius
BGC0001210.1	0.46	RiPP	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0001928.1	0.46	Other	(2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid	Streptomyces sp. MA37
BGC0000626.1	0.45	RiPP	thuricin	Bacillus thuringiensis
BGC0001551.1	0.45	RiPP	citrulassin E	Streptomyces glaucescens
BGC0001639.1	0.45	RiPP	klebsidin	Klebsiella pneumoniae

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NC_013037.1 - Region 4 - RRE-containing

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Location: 6,079,175 - 6,099,441 nt. (total: 20,267 nt) Show pHMM detection rules used

RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001639.1	0.22	RiPP	klebsidin	Klebsiella pneumoniae
BGC0001634.1	0.20	RiPP	keywimysin	Streptomyces sp. NRRL F-5702
BGC0001550.1	0.19	RiPP	citrulassin D	Streptomyces katrae
BGC0000575.1	0.19	RiPP	lariatin	Rhodococcus jostii
BGC0001889.1	0.17	RiPP	fusilassin	Thermobifida fusca YX
BGC0001496.1	0.17	RiPP	actinokineosin	Actinokineospora spheciospongiae
BGC0001645.1	0.17	RiPP	lagmysin	Streptomyces sp. NRRL S-118
BGC0000571.1	0.16	RiPP	burhizin	Paraburkholderia rhizoxinica HKI 454
BGC0000554.1	0.16	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000504.1	0.16	RiPP	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001639.1	0.55	RiPP	klebsidin	Klebsiella pneumoniae
BGC0001634.1	0.52	RiPP	keywimysin	Streptomyces sp. NRRL F-5702
BGC0001550.1	0.51	RiPP	citrulassin D	Streptomyces katrae
BGC0000575.1	0.51	RiPP	lariatin	Rhodococcus jostii
BGC0001889.1	0.49	RiPP	fusilassin	Thermobifida fusca YX
BGC0001496.1	0.48	RiPP	actinokineosin	Actinokineospora spheciospongiae
BGC0001645.1	0.48	RiPP	lagmysin	Streptomyces sp. NRRL S-118
BGC0000571.1	0.47	RiPP	burhizin	Paraburkholderia rhizoxinica HKI 454
BGC0000554.1	0.47	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000504.1	0.46	RiPP	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NC_013037.1 - Region 5 - arylpolyene,resorcinol

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Location: 6,938,406 - 6,967,790 nt. (total: 29,385 nt) Show pHMM detection rules used

Region on contig edge.

resorcinol: DarB
arylpolyene: (APE_KS1 or APE_KS2)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001526.1	0.48	Other	bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K	Synechocystis salina LEGE 06099
BGC0001525.1	0.45	Other	bartoloside 2, bartoloside 3, bartoloside 4	Synechocystis salina LEGE 06155
BGC0000836.1	0.45	Other	APE Ec	Escherichia coli CFT073
BGC0000272.1	0.41	Polyketide	spore pigment	Streptomyces collinus
BGC0000248.1	0.41	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0000231.1	0.38	Polyketide	griseusin	Streptomyces griseus
BGC0001897.1	0.38	Polyketide	cepacin A	Burkholderia ambifaria IOP40-10
BGC0001927.1	0.37	Other	A-94964	Streptomyces sp.
BGC0001197.1	0.37	Polyketide	frankiamicin	Frankia sp. EAN1pec
BGC0000234.1	0.36	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001526.1	0.57	Other	bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K	Synechocystis salina LEGE 06099
BGC0000836.1	0.57	Other	APE Ec	Escherichia coli CFT073
BGC0001525.1	0.56	Other	bartoloside 2, bartoloside 3, bartoloside 4	Synechocystis salina LEGE 06155
BGC0000272.1	0.53	Polyketide	spore pigment	Streptomyces collinus
BGC0000248.1	0.53	Polyketide	naphtocyclinone	Streptomyces arenae
BGC0001927.1	0.52	Other	A-94964	Streptomyces sp.
BGC0000231.1	0.51	Polyketide	griseusin	Streptomyces griseus
BGC0001897.1	0.51	Polyketide	cepacin A	Burkholderia ambifaria IOP40-10
BGC0001197.1	0.50	Polyketide	frankiamicin	Frankia sp. EAN1pec
BGC0000234.1	0.50	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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