GCF_900129945.1_IMG-taxon_2585428068_annotated_assembly_genomic - 3 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_FQXK01000003 (original name was: NZ_FQXK01000003.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 44.1	lanthipeptide-class-ii,cyclic-lactone-autoinducer,ranthipeptide	203,216	253,076	carnolysin A1 / carnolysin A2	RiPP:Lanthipeptide	71%

NZ_FQXK01000012 (original name was: NZ_FQXK01000012.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 58.1	lassopeptide,RRE-containing	54,152	88,655

NZ_FQXK01000046 (original name was: NZ_FQXK01000046.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 82.1	ranthipeptide	1	12,561

No secondary metabolite regions were found in these records:: NZ_FQXK01000079 (original name was: NZ_FQXK01000079.1); NZ_FQXK01000075 (original name was: NZ_FQXK01000075.1); NZ_FQXK01000081 (original name was: NZ_FQXK01000081.1); NZ_FQXK01000078 (original name was: NZ_FQXK01000078.1); NZ_FQXK01000072 (original name was: NZ_FQXK01000072.1); NZ_FQXK01000070 (original name was: NZ_FQXK01000070.1); NZ_FQXK01000067 (original name was: NZ_FQXK01000067.1); NZ_FQXK01000065 (original name was: NZ_FQXK01000065.1); NZ_FQXK01000083 (original name was: NZ_FQXK01000083.1); NZ_FQXK01000064 (original name was: NZ_FQXK01000064.1); NZ_FQXK01000063 (original name was: NZ_FQXK01000063.1); NZ_FQXK01000062 (original name was: NZ_FQXK01000062.1); NZ_FQXK01000061 (original name was: NZ_FQXK01000061.1); NZ_FQXK01000060 (original name was: NZ_FQXK01000060.1); NZ_FQXK01000059 (original name was: NZ_FQXK01000059.1); NZ_FQXK01000053 (original name was: NZ_FQXK01000053.1); NZ_FQXK01000052 (original name was: NZ_FQXK01000052.1); NZ_FQXK01000051 (original name was: NZ_FQXK01000051.1); NZ_FQXK01000054 (original name was: NZ_FQXK01000054.1); NZ_FQXK01000049 (original name was: NZ_FQXK01000049.1); NZ_FQXK01000047 (original name was: NZ_FQXK01000047.1); NZ_FQXK01000048 (original name was: NZ_FQXK01000048.1); NZ_FQXK01000021 (original name was: NZ_FQXK01000021.1); NZ_FQXK01000023 (original name was: NZ_FQXK01000023.1); NZ_FQXK01000019 (original name was: NZ_FQXK01000019.1); NZ_FQXK01000017 (original name was: NZ_FQXK01000017.1); NZ_FQXK01000076 (original name was: NZ_FQXK01000076.1); NZ_FQXK01000024 (original name was: NZ_FQXK01000024.1); NZ_FQXK01000055 (original name was: NZ_FQXK01000055.1); NZ_FQXK01000018 (original name was: NZ_FQXK01000018.1); NZ_FQXK01000001 (original name was: NZ_FQXK01000001.1); NZ_FQXK01000036 (original name was: NZ_FQXK01000036.1); NZ_FQXK01000016 (original name was: NZ_FQXK01000016.1); NZ_FQXK01000057 (original name was: NZ_FQXK01000057.1); NZ_FQXK01000015 (original name was: NZ_FQXK01000015.1); NZ_FQXK01000080 (original name was: NZ_FQXK01000080.1); NZ_FQXK01000014 (original name was: NZ_FQXK01000014.1); NZ_FQXK01000068 (original name was: NZ_FQXK01000068.1); NZ_FQXK01000005 (original name was: NZ_FQXK01000005.1); NZ_FQXK01000073 (original name was: NZ_FQXK01000073.1); NZ_FQXK01000042 (original name was: NZ_FQXK01000042.1); NZ_FQXK01000022 (original name was: NZ_FQXK01000022.1); NZ_FQXK01000058 (original name was: NZ_FQXK01000058.1); NZ_FQXK01000030 (original name was: NZ_FQXK01000030.1); NZ_FQXK01000010 (original name was: NZ_FQXK01000010.1); NZ_FQXK01000020 (original name was: NZ_FQXK01000020.1); NZ_FQXK01000007 (original name was: NZ_FQXK01000007.1); NZ_FQXK01000027 (original name was: NZ_FQXK01000027.1); NZ_FQXK01000011 (original name was: NZ_FQXK01000011.1); NZ_FQXK01000009 (original name was: NZ_FQXK01000009.1); NZ_FQXK01000004 (original name was: NZ_FQXK01000004.1); NZ_FQXK01000006 (original name was: NZ_FQXK01000006.1); NZ_FQXK01000056 (original name was: NZ_FQXK01000056.1); NZ_FQXK01000008 (original name was: NZ_FQXK01000008.1); NZ_FQXK01000025 (original name was: NZ_FQXK01000025.1); NZ_FQXK01000050 (original name was: NZ_FQXK01000050.1); NZ_FQXK01000026 (original name was: NZ_FQXK01000026.1); NZ_FQXK01000028 (original name was: NZ_FQXK01000028.1); NZ_FQXK01000071 (original name was: NZ_FQXK01000071.1); NZ_FQXK01000029 (original name was: NZ_FQXK01000029.1); NZ_FQXK01000033 (original name was: NZ_FQXK01000033.1); NZ_FQXK01000034 (original name was: NZ_FQXK01000034.1); NZ_FQXK01000031 (original name was: NZ_FQXK01000031.1); NZ_FQXK01000039 (original name was: NZ_FQXK01000039.1); NZ_FQXK01000077 (original name was: NZ_FQXK01000077.1); NZ_FQXK01000041 (original name was: NZ_FQXK01000041.1); NZ_FQXK01000074 (original name was: NZ_FQXK01000074.1); NZ_FQXK01000032 (original name was: NZ_FQXK01000032.1); NZ_FQXK01000044 (original name was: NZ_FQXK01000044.1); NZ_FQXK01000035 (original name was: NZ_FQXK01000035.1); NZ_FQXK01000069 (original name was: NZ_FQXK01000069.1); NZ_FQXK01000037 (original name was: NZ_FQXK01000037.1); NZ_FQXK01000082 (original name was: NZ_FQXK01000082.1); NZ_FQXK01000066 (original name was: NZ_FQXK01000066.1); NZ_FQXK01000038 (original name was: NZ_FQXK01000038.1); NZ_FQXK01000013 (original name was: NZ_FQXK01000013.1); NZ_FQXK01000043 (original name was: NZ_FQXK01000043.1); NZ_FQXK01000040 (original name was: NZ_FQXK01000040.1); NZ_FQXK01000045 (original name was: NZ_FQXK01000045.1)

Compact view

c00044_NZ_FQXK.. - Region 1 - cyclic-lactone-autoinducer,lanthipeptide-class-ii,ranthipeptide

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Location: 203,216 - 253,076 nt. (total: 49,861 nt) Show pHMM detection rules used

lanthipeptide-class-ii: cds(LANC_like and DUF4135)
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)
ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Lanthipeptides

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000500.1	0.70	RiPP	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0000504.1	0.63	RiPP	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0000517.1	0.51	RiPP	haloduracin β, haloduracin α	Bacillus halodurans C-125
BGC0001639.1	0.46	RiPP	klebsidin	Klebsiella pneumoniae
BGC0000516.1	0.45	RiPP	geobacillin II	Geobacillus thermodenitrificans
BGC0000543.1	0.45	RiPP	pep5	Staphylococcus epidermidis
BGC0000560.1	0.44	RiPP	subtilomycin	Bacillus subtilis
BGC0001210.1	0.43	RiPP	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0001311.1	0.42	RiPP	flavecins	Ruminococcus flavefaciens FD-1
BGC0000552.1	0.42	RiPP	SmbA, SmbB	Streptococcus mutans

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000500.1	0.66	RiPP	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0000554.1	0.65	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000626.1	0.61	RiPP	thuricin	Bacillus thuringiensis
BGC0000525.1	0.59	RiPP	lichenicidin VK21 A1, lichenicidin VK21 A2	Bacillus licheniformis
BGC0000516.1	0.59	RiPP	geobacillin II	Geobacillus thermodenitrificans
BGC0000504.1	0.59	RiPP	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0000517.1	0.58	RiPP	haloduracin β, haloduracin α	Bacillus halodurans C-125
BGC0000521.1	0.57	RiPP	lacticin 481	Lactococcus lactis subsp. lactis
BGC0001311.1	0.57	RiPP	flavecins	Ruminococcus flavefaciens FD-1
BGC0000552.1	0.57	RiPP	SmbA, SmbB	Streptococcus mutans

Similar known gene clusters

Lanthipeptide predictions

Lanthipeptide(s) for ctg44_188 - Putative Class II

ctg44_186 leader / core peptide: MTQENMNRIVGETFEDMSVAEMTMVQGS - GDLGAEFDhbDhbDhaPACVALDhbVAAAQQDhaDhaNNCAVAIDhaGDhaLDhaAIGDhaAVLDhaAIKC
ctg44_187 leader / core peptide: MSSVDMKNIVGDSFEDMSIAEMAMVQGS - GDLEGEDhaVIADhbLLAVDhaAAVGDhaAAGAIQVVKDhbIKGDhbC
allorf_217330_217422 leader / core peptide: LSISSSFIYA - DhaGDhbCNCPLFQYDhbHDVMVYFD
allorf_218253_218327 leader / core peptide: LRIIVHRLLTVHGI - NVVKFDhaCKDhaA
allorf_224954_225154 leader / core peptide: LELRKIVDKEIIDEALYWG - AYQVRIIKKYDhaLCNLVKIVLIDDhbNKQIVVDQDAILDhaHKEKDhaIRLLRR

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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Lanthipeptides

Core peptide predictions

ctg44_186 - Class II

Cleavage pHMM score: -0.60

RODEO score: 0

Monoisotopic mass: 4426.3 Da

Molecular weight: 4429.0 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 4447.0 Da N = 1; 4465.0 Da N = 2; 4483.0 Da N = 3; 4501.0 Da N = 4; 4519.1 Da N = 5; 4537.1 Da N = 6; 4555.1 Da N = 7; 4573.1 Da N = 8

ctg44_187 - Class II

Cleavage pHMM score: 0.90

RODEO score: 0

Monoisotopic mass: 3290.8 Da

Molecular weight: 3292.8 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 3310.8 Da N = 1; 3328.8 Da N = 2; 3346.8 Da N = 3; 3364.9 Da N = 4; 3382.9 Da N = 5

allorf_217330_217422 - Class II

Cleavage pHMM score: -6.70

RODEO score: 0

Monoisotopic mass: 2285.0 Da

Molecular weight: 2286.5 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 2304.6 Da N = 1

allorf_218253_218327 - Class II

Cleavage pHMM score: -5.50

RODEO score: 0

Monoisotopic mass: 1045.6 Da

Molecular weight: 1046.2 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 1064.3 Da N = 1

allorf_224954_225154 - Class II

Cleavage pHMM score: -4.60

RODEO score: 0

Monoisotopic mass: 5461.2 Da

Molecular weight: 5464.5 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 5482.5 Da N = 1; 5500.5 Da N = 2; 5518.6 Da N = 3

c00058_NZ_FQXK.. - Region 1 - RRE-containing,lassopeptide

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Location: 54,152 - 88,655 nt. (total: 34,504 nt) Show pHMM detection rules used

lassopeptide: (PF13471 and Asn_synthase or micJ25 or mcjC)
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Lasso peptides

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001634.1	0.62	RiPP	keywimysin	Streptomyces sp. NRRL F-5702
BGC0000885.1	0.50	Other	4-hydroxy-3-nitrosobenzamide	Streptomyces murayamaensis
BGC0000571.1	0.50	RiPP	burhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001639.1	0.45	RiPP	klebsidin	Klebsiella pneumoniae
BGC0000578.1	0.43	RiPP	SRO15-2005	Streptomyces filamentosus NRRL 15998
BGC0001356.1	0.42	RiPP	paeninodin	Paenibacillus dendritiformis C454
BGC0000796.1	0.36	Saccharide	S-layer glycan	Paenibacillus alvei
BGC0001395.1	0.34	Other	teichomycin	Actinoplanes teichomyceticus
BGC0000500.1	0.31	RiPP	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0000516.1	0.31	RiPP	geobacillin II	Geobacillus thermodenitrificans

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001634.1	0.65	RiPP	keywimysin	Streptomyces sp. NRRL F-5702
BGC0000885.1	0.59	Other	4-hydroxy-3-nitrosobenzamide	Streptomyces murayamaensis
BGC0000571.1	0.59	RiPP	burhizin	Paraburkholderia rhizoxinica HKI 454
BGC0000796.1	0.57	Saccharide	S-layer glycan	Paenibacillus alvei
BGC0000578.1	0.56	RiPP	SRO15-2005	Streptomyces filamentosus NRRL 15998
BGC0001639.1	0.56	RiPP	klebsidin	Klebsiella pneumoniae
BGC0001356.1	0.54	RiPP	paeninodin	Paenibacillus dendritiformis C454
BGC0001395.1	0.51	Other	teichomycin	Actinoplanes teichomyceticus
BGC0000716.1	0.49	Saccharide	spectinomycin	Streptomyces netropsis
BGC0000742.1	0.48	Saccharide	capsular polysaccharide	Streptococcus agalactiae

Similar known gene clusters

No matches found.

Lasso peptide predictions

Lassopeptide(s) for ctg58_62 - Putative Class II

ctg58_62 leader / core peptide / cleaved tail: MKAWNTPVMESLEINETAGGYNQITE - HDGVINYSAGIPAEEYASGPLPR

Legend:

Red: Putative macrolactam
Purple: Putative cleaved off residues

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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Lasso peptides

Core peptide predictions

ctg58_62 - Class II: Cleavage pHMM score: -11.50; RODEO score: 19; Monoisotopic mass: 2394.2 Da; Molecular weight: 2395.6 Da; Number of bridges: 0

c00082_NZ_FQXK.. - Region 1 - ranthipeptide

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Location: 1 - 12,561 nt. (total: 12,561 nt) Show pHMM detection rules used

Region on contig edge.

ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	ranthipeptide	Similarity score	Type	Compound(s)	Organism
BGC0000695.1		0.08	Saccharide	fortimicin	Micromonospora olivasterospora
BGC0000599.1		0.08	RiPP	thuricin CD α, thuricin CD β	Bacillus thuringiensis

Reference	Aggregated	Similarity score	Type	Compound(s)	Organism
BGC0000695.1		0.32	Saccharide	fortimicin	Micromonospora olivasterospora
BGC0000599.1		0.30	RiPP	thuricin CD α, thuricin CD β	Bacillus thuringiensis

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names