GCF_029094545.1_ASM2909454v1_genomic - 7 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP117835.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	siderophore	192,307	205,782	petrobactin	Other	33%
Region 1.2	T3PKS	337,624	378,721	7-deoxypactamycin	Polyketide:Iterative type I + Saccharide:Hybrid/tailoring	3%
Region 1.3	ectoine	600,661	611,050	ectoine	Other	66%
Region 1.4	betalactone	711,189	740,207	fengycin	NRP	46%
Region 1.5	terpene	1,291,544	1,312,383	carotenoid	Terpene	66%
Region 1.6	siderophore	1,803,705	1,820,408

NZ_CP117836.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 2.1	transAT-PKS	66,798	122,762	pellasoren	NRP + Polyketide:Modular type I	33%

Compact view

NZ_CP117835.1 - Region 1 - siderophore

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Location: 192,307 - 205,782 nt. (total: 13,476 nt) Show pHMM detection rules used

siderophore: IucA_IucC

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core biosynthetic genes

additional biosynthetic genes

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Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000942.1	0.49	Other	petrobactin	Bacillus anthracis str. Ames
BGC0001499.1	0.31	Other	aerobactin	Pantoea ananatis
BGC0001713.1	0.31	Other	ochrobactin	Ochrobactrum anthropi
BGC0001531.1	0.31	Other	bisucaberin B	Tenacibaculum mesophilum
BGC0000295.1	0.31	NRP	acinetoferrin	Acinetobacter haemolyticus
BGC0000939.1	0.30	Other	aerobactin	Grimontia hollisae
BGC0001408.1	0.23	Other	xanthoferrin	Xanthomonas oryzae pv. oryzae KACC 10331
BGC0000946.1	0.22	Other	vibrioferrin	Vibrio parahaemolyticus
BGC0001555.1	0.22	RiPP	colicin V	Escherichia coli chi7122
BGC0000410.1	0.19	NRP	pseudomonine	Pseudomonas fluorescens

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000942.1	0.78	Other	petrobactin	Bacillus anthracis str. Ames
BGC0001499.1	0.65	Other	aerobactin	Pantoea ananatis
BGC0001713.1	0.65	Other	ochrobactin	Ochrobactrum anthropi
BGC0001531.1	0.65	Other	bisucaberin B	Tenacibaculum mesophilum
BGC0000295.1	0.64	NRP	acinetoferrin	Acinetobacter haemolyticus
BGC0000939.1	0.64	Other	aerobactin	Grimontia hollisae
BGC0001408.1	0.56	Other	xanthoferrin	Xanthomonas oryzae pv. oryzae KACC 10331
BGC0000946.1	0.55	Other	vibrioferrin	Vibrio parahaemolyticus
BGC0001555.1	0.55	RiPP	colicin V	Escherichia coli chi7122
BGC0000410.1	0.50	NRP	pseudomonine	Pseudomonas fluorescens

Similar known gene clusters

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Detailed TIGRFAM domain annotation

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NZ_CP117835.1 - Region 2 - T3PKS

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Location: 337,624 - 378,721 nt. (total: 41,098 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

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core biosynthetic genes

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regulatory genes

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NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000282.1	0.34	Polyketide	alkylresorcinol	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001938.1	0.31	Polyketide	entotheonella	Candidatus Entotheonella serta
BGC0001962.1	0.31	Polyketide	hierridin B, hierridin C	Cyanobium sp. LEGE 06113
BGC0001831.1	0.22	Polyketide	alkylpyrone-407, alkylpyrone-393	Myxococcus xanthus DK 1622
BGC0000937.1	0.18	Other	fosfazinomycin A	Streptomyces sp. WM6372
BGC0000772.1	0.16	Saccharide	lipopolysaccharide	Brucella melitensis
BGC0002034.1	0.14	Other	perquinoline A, perquinoline B, perquinoline C	Streptomyces sp. IB2014 016-6
BGC0001808.1	0.14	Other	toyocamycin	Streptomyces diastatochromogenes
BGC0000881.1	0.14	Other	toyocamycin	Streptomyces ahygroscopicus subsp. wuzhouensis
BGC0001783.1	0.14	Other	streptonigrin	Streptomyces flocculus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000282.1	0.67	Polyketide	alkylresorcinol	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001938.1	0.65	Polyketide	entotheonella	Candidatus Entotheonella serta
BGC0001962.1	0.64	Polyketide	hierridin B, hierridin C	Cyanobium sp. LEGE 06113
BGC0001831.1	0.55	Polyketide	alkylpyrone-407, alkylpyrone-393	Myxococcus xanthus DK 1622
BGC0000937.1	0.50	Other	fosfazinomycin A	Streptomyces sp. WM6372
BGC0000772.1	0.46	Saccharide	lipopolysaccharide	Brucella melitensis
BGC0002034.1	0.44	Other	perquinoline A, perquinoline B, perquinoline C	Streptomyces sp. IB2014 016-6
BGC0001808.1	0.43	Other	toyocamycin	Streptomyces diastatochromogenes
BGC0000881.1	0.43	Other	toyocamycin	Streptomyces ahygroscopicus subsp. wuzhouensis
BGC0001783.1	0.43	Other	streptonigrin	Streptomyces flocculus

Similar known gene clusters

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NZ_CP117835.1 - Region 3 - ectoine

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Location: 600,661 - 611,050 nt. (total: 10,390 nt) Show pHMM detection rules used

ectoine: ectoine_synt

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core biosynthetic genes

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000858.1	0.41	Other	ectoine	Methylobacter marinus
BGC0000859.1	0.41	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000852.1	0.40	Other	ectoine	Sporosarcina pasteurii
BGC0000855.1	0.34	Other	ectoine	Methylomicrobium kenyense
BGC0000856.1	0.33	Other	ectoine	Methylophaga thalassica
BGC0000853.1	0.33	Other	ectoine	Streptomyces anulatus
BGC0000857.1	0.31	Other	ectoine	Methylophaga alcalica
BGC0000854.1	0.29	Other	ectoine	Methylomicrobium alcaliphilum 20Z
BGC0000860.1	0.26	Other	ectoine	Methylarcula marina
BGC0001525.1	0.17	Other	bartoloside 2, bartoloside 3, bartoloside 4	Synechocystis salina LEGE 06155

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000858.1	0.73	Other	ectoine	Methylobacter marinus
BGC0000859.1	0.72	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000852.1	0.72	Other	ectoine	Sporosarcina pasteurii
BGC0000855.1	0.67	Other	ectoine	Methylomicrobium kenyense
BGC0000856.1	0.67	Other	ectoine	Methylophaga thalassica
BGC0000853.1	0.66	Other	ectoine	Streptomyces anulatus
BGC0000857.1	0.64	Other	ectoine	Methylophaga alcalica
BGC0000854.1	0.62	Other	ectoine	Methylomicrobium alcaliphilum 20Z
BGC0000860.1	0.59	Other	ectoine	Methylarcula marina
BGC0001525.1	0.48	Other	bartoloside 2, bartoloside 3, bartoloside 4	Synechocystis salina LEGE 06155

Similar known gene clusters

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Detailed TIGRFAM domain annotation

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NZ_CP117835.1 - Region 4 - betalactone

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Location: 711,189 - 740,207 nt. (total: 29,019 nt) Show pHMM detection rules used

betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

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KnownClusterBlast

Pfam domains

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001465.1	0.22	Other	bromopyrroles/bromophenols	Marinomonas mediterranea MMB-1
BGC0000890.1	0.22	Other (Aminocoumarin)	pentabromopseudilin	Pseudoalteromonas phenolica O-BC30
BGC0000891.1	0.22	Other (Aminocoumarin)	pentabromopseudilin	Pseudoalteromonas luteoviolacea 2ta16
BGC0000234.1	0.21	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0000258.1	0.21	Polyketide	prodigiosin	Serratia sp.
BGC0001399.1	0.20	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000259.1	0.20	Polyketide	prodigiosin	Serratia marcescens
BGC0001897.1	0.20	Polyketide	cepacin A	Burkholderia ambifaria IOP40-10
BGC0000343.1	0.19	NRP	enterobactin	Pseudomonas sp. J465
BGC0000260.1	0.19	Polyketide	prodigiosin	Hahella chejuensis KCTC 2396

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001465.1	0.55	Other	bromopyrroles/bromophenols	Marinomonas mediterranea MMB-1
BGC0000890.1	0.55	Other (Aminocoumarin)	pentabromopseudilin	Pseudoalteromonas phenolica O-BC30
BGC0000891.1	0.55	Other (Aminocoumarin)	pentabromopseudilin	Pseudoalteromonas luteoviolacea 2ta16
BGC0000234.1	0.54	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0000258.1	0.54	Polyketide	prodigiosin	Serratia sp.
BGC0001399.1	0.53	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000259.1	0.53	Polyketide	prodigiosin	Serratia marcescens
BGC0001897.1	0.52	Polyketide	cepacin A	Burkholderia ambifaria IOP40-10
BGC0000343.1	0.51	NRP	enterobactin	Pseudomonas sp. J465
BGC0000260.1	0.50	Polyketide	prodigiosin	Hahella chejuensis KCTC 2396

Similar known gene clusters

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Detailed TIGRFAM domain annotation

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NZ_CP117835.1 - Region 5 - terpene

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Location: 1,291,544 - 1,312,383 nt. (total: 20,840 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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core biosynthetic genes

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KnownClusterBlast

Pfam domains

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000645.1	0.51	Terpene	carotenoid	Halobacillus halophilus DSM 2266
BGC0000647.1	0.36	Terpene	carotenoid	Rhodobacter sphaeroides
BGC0000648.1	0.21	Terpene	carotenoid	Myxococcus xanthus
BGC0000633.1	0.21	Terpene	carotenoid	Streptomyces avermitilis
BGC0001227.1	0.21	Terpene	isorenieratene	Streptomyces collinus Tu 365
BGC0000204.1	0.20	Polyketide	benastatin A, benastatin B, BE-43767, TAN1532B	Streptomyces sp. A2991200
BGC0000630.1	0.20	Terpene	(2R,3S,3'S)-2-hydroxyastaxanthin	Paracoccus haeundaensis
BGC0000656.1	0.19	Terpene	zeaxanthin	Xanthobacter autotrophicus Py2
BGC0000664.1	0.18	Terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001456.1	0.18	Terpene	isorenieratene	Streptomyces argillaceus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000645.1	0.79	Terpene	carotenoid	Halobacillus halophilus DSM 2266
BGC0000647.1	0.69	Terpene	carotenoid	Rhodobacter sphaeroides
BGC0000648.1	0.54	Terpene	carotenoid	Myxococcus xanthus
BGC0000633.1	0.53	Terpene	carotenoid	Streptomyces avermitilis
BGC0001227.1	0.53	Terpene	isorenieratene	Streptomyces collinus Tu 365
BGC0000204.1	0.53	Polyketide	benastatin A, benastatin B, BE-43767, TAN1532B	Streptomyces sp. A2991200
BGC0000630.1	0.52	Terpene	(2R,3S,3'S)-2-hydroxyastaxanthin	Paracoccus haeundaensis
BGC0000656.1	0.50	Terpene	zeaxanthin	Xanthobacter autotrophicus Py2
BGC0000664.1	0.50	Terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001456.1	0.50	Terpene	isorenieratene	Streptomyces argillaceus

Similar known gene clusters

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Detailed TIGRFAM domain annotation

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NZ_CP117835.1 - Region 6 - siderophore

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Location: 1,803,705 - 1,820,408 nt. (total: 16,704 nt) Show pHMM detection rules used

siderophore: IucA_IucC

Legend:

core biosynthetic genes

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transport-related genes

regulatory genes

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resistance

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KnownClusterBlast

Pfam domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001478.1	0.28	Other	desferrioxamine E	Streptomyces sp. ID38640
BGC0000941.1	0.27	Other	desferrioxamin B	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001572.1	0.25	Other	desferrioxamine E	Pantoea agglomerans
BGC0000940.1	0.23	Other	desferrioxamin B, desferrioxamine E	Streptomyces coelicolor A3(2)
BGC0001453.1	0.23	Other	desferrioxamine	Streptomyces argillaceus
BGC0000946.1	0.23	Other	vibrioferrin	Vibrio parahaemolyticus
BGC0000942.1	0.22	Other	petrobactin	Bacillus anthracis str. Ames
BGC0000295.1	0.20	NRP	acinetoferrin	Acinetobacter haemolyticus
BGC0001713.1	0.20	Other	ochrobactin	Ochrobactrum anthropi
BGC0001499.1	0.19	Other	aerobactin	Pantoea ananatis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001478.1	0.62	Other	desferrioxamine E	Streptomyces sp. ID38640
BGC0000941.1	0.60	Other	desferrioxamin B	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001572.1	0.59	Other	desferrioxamine E	Pantoea agglomerans
BGC0000940.1	0.57	Other	desferrioxamin B, desferrioxamine E	Streptomyces coelicolor A3(2)
BGC0001453.1	0.56	Other	desferrioxamine	Streptomyces argillaceus
BGC0000946.1	0.56	Other	vibrioferrin	Vibrio parahaemolyticus
BGC0000942.1	0.55	Other	petrobactin	Bacillus anthracis str. Ames
BGC0000295.1	0.53	NRP	acinetoferrin	Acinetobacter haemolyticus
BGC0001713.1	0.52	Other	ochrobactin	Ochrobactrum anthropi
BGC0001499.1	0.51	Other	aerobactin	Pantoea ananatis

Similar known gene clusters

No matches found.

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NZ_CP117836.1 - Region 1 - transAT-PKS

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Location: 66,798 - 122,762 nt. (total: 55,965 nt) Show pHMM detection rules used

transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))

Legend:

core biosynthetic genes

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NRPS/PKS domains

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NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000044.1	0.23	Polyketide	dawenol	Stigmatella aurantiaca DW4/3-1
BGC0000194.1	0.22	Polyketide	actinorhodin	Streptomyces coelicolor A3(2)
BGC0001281.1	0.22	Polyketide	ustilagic acid	Ustilago maydis 521
BGC0002000.1	0.21	Polyketide	setomimycin	Streptomyces aurantiacus JA 4570
BGC0001927.1	0.21	Other	A-94964	Streptomyces sp.
BGC0001591.1	0.20	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.20	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0000205.1	0.20	Polyketide	bryostatin	Candidatus Endobugula sertula
BGC0000838.1	0.19	Polyketide	flexirubin	Flavobacterium johnsoniae UW101
BGC0001636.1	0.18	NRP	KK-1	Curvularia clavata

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000044.1	0.56	Polyketide	dawenol	Stigmatella aurantiaca DW4/3-1
BGC0000194.1	0.55	Polyketide	actinorhodin	Streptomyces coelicolor A3(2)
BGC0001281.1	0.55	Polyketide	ustilagic acid	Ustilago maydis 521
BGC0002000.1	0.53	Polyketide	setomimycin	Streptomyces aurantiacus JA 4570
BGC0001927.1	0.53	Other	A-94964	Streptomyces sp.
BGC0001591.1	0.53	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.53	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0000205.1	0.52	Polyketide	bryostatin	Candidatus Endobugula sertula
BGC0000838.1	0.51	Polyketide	flexirubin	Flavobacterium johnsoniae UW101
BGC0001636.1	0.50	NRP	KK-1	Curvularia clavata

Similar known gene clusters

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 66797 - 122762:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ohmal - ohmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg2_98

PKS_AT (6..290): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 62.5%; inactive: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 41.6
Methoxymalonyl-CoA: 27.1
inactive: 26.0
Methylmalonyl-CoA: 20.3
Propionyl-CoA: 15.2
2-Methylbutyryl-CoA: 9.4
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

ctg2_103

PKS_AT (9..302): pk

ATSignature: (unknown)

No matches above 50%

minowa: trans-1,2-CPDA

Prediction, score:

trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0
Malonyl-CoA: -1.6