Select genomic region:
Overview
1.1
1.2
1.3
1.4
1.5
1.6
2.1

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP117835.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | siderophore | 192,307 | 205,782 | petrobactin | Other | 33%
Region 1.2 | T3PKS | 337,624 | 378,721 | 7-deoxypactamycin | Polyketide:Iterative type I + Saccharide:Hybrid/tailoring | 3%
Region 1.3 | ectoine | 600,661 | 611,050 | ectoine | Other | 66%
Region 1.4 | betalactone | 711,189 | 740,207 | fengycin | NRP | 46%
Region 1.5 | terpene | 1,291,544 | 1,312,383 | carotenoid | Terpene | 66%
Region 1.6 | siderophore | 1,803,705 | 1,820,408 |

NZ_CP117836.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 2.1 | transAT-PKS | 66,798 | 122,762 | pellasoren | NRP + Polyketide:Modular type I | 33%

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | siderophore | 192,307 | 205,782 | petrobactin | Other | 33%
Region 1.2 | T3PKS | 337,624 | 378,721 | 7-deoxypactamycin | Polyketide:Iterative type I + Saccharide:Hybrid/tailoring | 3%
Region 1.3 | ectoine | 600,661 | 611,050 | ectoine | Other | 66%
Region 1.4 | betalactone | 711,189 | 740,207 | fengycin | NRP | 46%
Region 1.5 | terpene | 1,291,544 | 1,312,383 | carotenoid | Terpene | 66%
Region 1.6 | siderophore | 1,803,705 | 1,820,408 |
Region 2.1 | transAT-PKS | 66,798 | 122,762 | pellasoren | NRP + Polyketide:Modular type I | 33%

Compact view
NZ_CP117835.1 - Region 1 - siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 192,307 - 205,782 nt. (total: 13,476 nt) Show pHMM detection rules used
siderophore: IucA_IucC

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | siderophore | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000942.1 |  | 0.49 | Other | petrobactin | Bacillus anthracis str. Ames
BGC0001499.1 |  | 0.31 | Other | aerobactin | Pantoea ananatis
BGC0001713.1 |  | 0.31 | Other | ochrobactin | Ochrobactrum anthropi
BGC0001531.1 |  | 0.31 | Other | bisucaberin B | Tenacibaculum mesophilum
BGC0000295.1 |  | 0.31 | NRP | acinetoferrin | Acinetobacter haemolyticus
BGC0000939.1 |  | 0.30 | Other | aerobactin | Grimontia hollisae
BGC0001408.1 |  | 0.23 | Other | xanthoferrin | Xanthomonas oryzae pv. oryzae KACC 10331
BGC0000946.1 |  | 0.22 | Other | vibrioferrin | Vibrio parahaemolyticus
BGC0001555.1 |  | 0.22 | RiPP | colicin V | Escherichia coli chi7122
BGC0000410.1 |  | 0.19 | NRP | pseudomonine | Pseudomonas fluorescens

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000942.1 |  | 0.78 | Other | petrobactin | Bacillus anthracis str. Ames
BGC0001499.1 |  | 0.65 | Other | aerobactin | Pantoea ananatis
BGC0001713.1 |  | 0.65 | Other | ochrobactin | Ochrobactrum anthropi
BGC0001531.1 |  | 0.65 | Other | bisucaberin B | Tenacibaculum mesophilum
BGC0000295.1 |  | 0.64 | NRP | acinetoferrin | Acinetobacter haemolyticus
BGC0000939.1 |  | 0.64 | Other | aerobactin | Grimontia hollisae
BGC0001408.1 |  | 0.56 | Other | xanthoferrin | Xanthomonas oryzae pv. oryzae KACC 10331
BGC0000946.1 |  | 0.55 | Other | vibrioferrin | Vibrio parahaemolyticus
BGC0001555.1 |  | 0.55 | RiPP | colicin V | Escherichia coli chi7122
BGC0000410.1 |  | 0.50 | NRP | pseudomonine | Pseudomonas fluorescens

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP117835.1 - Region 2 - T3PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 337,624 - 378,721 nt. (total: 41,098 nt) Show pHMM detection rules used
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | T3PKS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000282.1 |  | 0.34 | Polyketide | alkylresorcinol | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001938.1 |  | 0.31 | Polyketide | entotheonella | Candidatus Entotheonella serta
BGC0001962.1 |  | 0.31 | Polyketide | hierridin B, hierridin C | Cyanobium sp. LEGE 06113
BGC0001831.1 |  | 0.22 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0000937.1 |  | 0.18 | Other | fosfazinomycin A | Streptomyces sp. WM6372
BGC0000772.1 |  | 0.16 | Saccharide | lipopolysaccharide | Brucella melitensis
BGC0002034.1 |  | 0.14 | Other | perquinoline A, perquinoline B, perquinoline C | Streptomyces sp. IB2014 016-6
BGC0001808.1 |  | 0.14 | Other | toyocamycin | Streptomyces diastatochromogenes
BGC0000881.1 |  | 0.14 | Other | toyocamycin | Streptomyces ahygroscopicus subsp. wuzhouensis
BGC0001783.1 |  | 0.14 | Other | streptonigrin | Streptomyces flocculus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000282.1 |  | 0.67 | Polyketide | alkylresorcinol | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001938.1 |  | 0.65 | Polyketide | entotheonella | Candidatus Entotheonella serta
BGC0001962.1 |  | 0.64 | Polyketide | hierridin B, hierridin C | Cyanobium sp. LEGE 06113
BGC0001831.1 |  | 0.55 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0000937.1 |  | 0.50 | Other | fosfazinomycin A | Streptomyces sp. WM6372
BGC0000772.1 |  | 0.46 | Saccharide | lipopolysaccharide | Brucella melitensis
BGC0002034.1 |  | 0.44 | Other | perquinoline A, perquinoline B, perquinoline C | Streptomyces sp. IB2014 016-6
BGC0001808.1 |  | 0.43 | Other | toyocamycin | Streptomyces diastatochromogenes
BGC0000881.1 |  | 0.43 | Other | toyocamycin | Streptomyces ahygroscopicus subsp. wuzhouensis
BGC0001783.1 |  | 0.43 | Other | streptonigrin | Streptomyces flocculus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP117835.1 - Region 3 - ectoine
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 600,661 - 611,050 nt. (total: 10,390 nt) Show pHMM detection rules used
ectoine: ectoine_synt

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | ectoine | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000858.1 |  | 0.41 | Other | ectoine | Methylobacter marinus
BGC0000859.1 |  | 0.41 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000852.1 |  | 0.40 | Other | ectoine | Sporosarcina pasteurii
BGC0000855.1 |  | 0.34 | Other | ectoine | Methylomicrobium kenyense
BGC0000856.1 |  | 0.33 | Other | ectoine | Methylophaga thalassica
BGC0000853.1 |  | 0.33 | Other | ectoine | Streptomyces anulatus
BGC0000857.1 |  | 0.31 | Other | ectoine | Methylophaga alcalica
BGC0000854.1 |  | 0.29 | Other | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0000860.1 |  | 0.26 | Other | ectoine | Methylarcula marina
BGC0001525.1 |  | 0.17 | Other | bartoloside 2, bartoloside 3, bartoloside 4 | Synechocystis salina LEGE 06155

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000858.1 |  | 0.73 | Other | ectoine | Methylobacter marinus
BGC0000859.1 |  | 0.72 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000852.1 |  | 0.72 | Other | ectoine | Sporosarcina pasteurii
BGC0000855.1 |  | 0.67 | Other | ectoine | Methylomicrobium kenyense
BGC0000856.1 |  | 0.67 | Other | ectoine | Methylophaga thalassica
BGC0000853.1 |  | 0.66 | Other | ectoine | Streptomyces anulatus
BGC0000857.1 |  | 0.64 | Other | ectoine | Methylophaga alcalica
BGC0000854.1 |  | 0.62 | Other | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0000860.1 |  | 0.59 | Other | ectoine | Methylarcula marina
BGC0001525.1 |  | 0.48 | Other | bartoloside 2, bartoloside 3, bartoloside 4 | Synechocystis salina LEGE 06155

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP117835.1 - Region 4 - betalactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 711,189 - 740,207 nt. (total: 29,019 nt) Show pHMM detection rules used
betalactone: (HMGL-like and AMP-binding)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | betalactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001465.1 |  | 0.22 | Other | bromopyrroles/bromophenols | Marinomonas mediterranea MMB-1
BGC0000890.1 |  | 0.22 | Other (Aminocoumarin) | pentabromopseudilin | Pseudoalteromonas phenolica O-BC30
BGC0000891.1 |  | 0.22 | Other (Aminocoumarin) | pentabromopseudilin | Pseudoalteromonas luteoviolacea 2ta16
BGC0000234.1 |  | 0.21 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0000258.1 |  | 0.21 | Polyketide | prodigiosin | Serratia sp.
BGC0001399.1 |  | 0.20 | NRP | fellutamide B | Aspergillus nidulans FGSC A4
BGC0000259.1 |  | 0.20 | Polyketide | prodigiosin | Serratia marcescens
BGC0001897.1 |  | 0.20 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0000343.1 |  | 0.19 | NRP | enterobactin | Pseudomonas sp. J465
BGC0000260.1 |  | 0.19 | Polyketide | prodigiosin | Hahella chejuensis KCTC 2396

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001465.1 |  | 0.55 | Other | bromopyrroles/bromophenols | Marinomonas mediterranea MMB-1
BGC0000890.1 |  | 0.55 | Other (Aminocoumarin) | pentabromopseudilin | Pseudoalteromonas phenolica O-BC30
BGC0000891.1 |  | 0.55 | Other (Aminocoumarin) | pentabromopseudilin | Pseudoalteromonas luteoviolacea 2ta16
BGC0000234.1 |  | 0.54 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0000258.1 |  | 0.54 | Polyketide | prodigiosin | Serratia sp.
BGC0001399.1 |  | 0.53 | NRP | fellutamide B | Aspergillus nidulans FGSC A4
BGC0000259.1 |  | 0.53 | Polyketide | prodigiosin | Serratia marcescens
BGC0001897.1 |  | 0.52 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0000343.1 |  | 0.51 | NRP | enterobactin | Pseudomonas sp. J465
BGC0000260.1 |  | 0.50 | Polyketide | prodigiosin | Hahella chejuensis KCTC 2396

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP117835.1 - Region 5 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,291,544 - 1,312,383 nt. (total: 20,840 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000645.1 |  | 0.51 | Terpene | carotenoid | Halobacillus halophilus DSM 2266
BGC0000647.1 |  | 0.36 | Terpene | carotenoid | Rhodobacter sphaeroides
BGC0000648.1 |  | 0.21 | Terpene | carotenoid | Myxococcus xanthus
BGC0000633.1 |  | 0.21 | Terpene | carotenoid | Streptomyces avermitilis
BGC0001227.1 |  | 0.21 | Terpene | isorenieratene | Streptomyces collinus Tu 365
BGC0000204.1 |  | 0.20 | Polyketide | benastatin A, benastatin B, BE-43767, TAN1532B | Streptomyces sp. A2991200
BGC0000630.1 |  | 0.20 | Terpene | (2R,3S,3'S)-2-hydroxyastaxanthin | Paracoccus haeundaensis
BGC0000656.1 |  | 0.19 | Terpene | zeaxanthin | Xanthobacter autotrophicus Py2
BGC0000664.1 |  | 0.18 | Terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001456.1 |  | 0.18 | Terpene | isorenieratene | Streptomyces argillaceus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000645.1 |  | 0.79 | Terpene | carotenoid | Halobacillus halophilus DSM 2266
BGC0000647.1 |  | 0.69 | Terpene | carotenoid | Rhodobacter sphaeroides
BGC0000648.1 |  | 0.54 | Terpene | carotenoid | Myxococcus xanthus
BGC0000633.1 |  | 0.53 | Terpene | carotenoid | Streptomyces avermitilis
BGC0001227.1 |  | 0.53 | Terpene | isorenieratene | Streptomyces collinus Tu 365
BGC0000204.1 |  | 0.53 | Polyketide | benastatin A, benastatin B, BE-43767, TAN1532B | Streptomyces sp. A2991200
BGC0000630.1 |  | 0.52 | Terpene | (2R,3S,3'S)-2-hydroxyastaxanthin | Paracoccus haeundaensis
BGC0000656.1 |  | 0.50 | Terpene | zeaxanthin | Xanthobacter autotrophicus Py2
BGC0000664.1 |  | 0.50 | Terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001456.1 |  | 0.50 | Terpene | isorenieratene | Streptomyces argillaceus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP117835.1 - Region 6 - siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,803,705 - 1,820,408 nt. (total: 16,704 nt) Show pHMM detection rules used
siderophore: IucA_IucC

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | siderophore | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001478.1 |  | 0.28 | Other | desferrioxamine E | Streptomyces sp. ID38640
BGC0000941.1 |  | 0.27 | Other | desferrioxamin B | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001572.1 |  | 0.25 | Other | desferrioxamine E | Pantoea agglomerans
BGC0000940.1 |  | 0.23 | Other | desferrioxamin B, desferrioxamine E | Streptomyces coelicolor A3(2)
BGC0001453.1 |  | 0.23 | Other | desferrioxamine | Streptomyces argillaceus
BGC0000946.1 |  | 0.23 | Other | vibrioferrin | Vibrio parahaemolyticus
BGC0000942.1 |  | 0.22 | Other | petrobactin | Bacillus anthracis str. Ames
BGC0000295.1 |  | 0.20 | NRP | acinetoferrin | Acinetobacter haemolyticus
BGC0001713.1 |  | 0.20 | Other | ochrobactin | Ochrobactrum anthropi
BGC0001499.1 |  | 0.19 | Other | aerobactin | Pantoea ananatis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001478.1 |  | 0.62 | Other | desferrioxamine E | Streptomyces sp. ID38640
BGC0000941.1 |  | 0.60 | Other | desferrioxamin B | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001572.1 |  | 0.59 | Other | desferrioxamine E | Pantoea agglomerans
BGC0000940.1 |  | 0.57 | Other | desferrioxamin B, desferrioxamine E | Streptomyces coelicolor A3(2)
BGC0001453.1 |  | 0.56 | Other | desferrioxamine | Streptomyces argillaceus
BGC0000946.1 |  | 0.56 | Other | vibrioferrin | Vibrio parahaemolyticus
BGC0000942.1 |  | 0.55 | Other | petrobactin | Bacillus anthracis str. Ames
BGC0000295.1 |  | 0.53 | NRP | acinetoferrin | Acinetobacter haemolyticus
BGC0001713.1 |  | 0.52 | Other | ochrobactin | Ochrobactrum anthropi
BGC0001499.1 |  | 0.51 | Other | aerobactin | Pantoea ananatis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
NZ_CP117836.1 - Region 1 - transAT-PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 66,798 - 122,762 nt. (total: 55,965 nt) Show pHMM detection rules used
transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | transAT-PKS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000044.1 |  | 0.23 | Polyketide | dawenol | Stigmatella aurantiaca DW4/3-1
BGC0000194.1 |  | 0.22 | Polyketide | actinorhodin | Streptomyces coelicolor A3(2)
BGC0001281.1 |  | 0.22 | Polyketide | ustilagic acid | Ustilago maydis 521
BGC0002000.1 |  | 0.21 | Polyketide | setomimycin | Streptomyces aurantiacus JA 4570
BGC0001927.1 |  | 0.21 | Other | A-94964 | Streptomyces sp.
BGC0001591.1 |  | 0.20 | Other | fatty acid enol ester | uncultured bacterium CSLC2
BGC0001688.1 |  | 0.20 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0000205.1 |  | 0.20 | Polyketide | bryostatin | Candidatus Endobugula sertula
BGC0000838.1 |  | 0.19 | Polyketide | flexirubin | Flavobacterium johnsoniae UW101
BGC0001636.1 |  | 0.18 | NRP | KK-1 | Curvularia clavata

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000044.1 |  | 0.56 | Polyketide | dawenol | Stigmatella aurantiaca DW4/3-1
BGC0000194.1 |  | 0.55 | Polyketide | actinorhodin | Streptomyces coelicolor A3(2)
BGC0001281.1 |  | 0.55 | Polyketide | ustilagic acid | Ustilago maydis 521
BGC0002000.1 |  | 0.53 | Polyketide | setomimycin | Streptomyces aurantiacus JA 4570
BGC0001927.1 |  | 0.53 | Other | A-94964 | Streptomyces sp.
BGC0001591.1 |  | 0.53 | Other | fatty acid enol ester | uncultured bacterium CSLC2
BGC0001688.1 |  | 0.53 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0000205.1 |  | 0.52 | Polyketide | bryostatin | Candidatus Endobugula sertula
BGC0000838.1 |  | 0.51 | Polyketide | flexirubin | Flavobacterium johnsoniae UW101
BGC0001636.1 |  | 0.50 | NRP | KK-1 | Curvularia clavata

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 66797 - 122762:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (ohmal - ohmal)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg2_98: mal
  PKS_AT (6..290): mal
  ATSignature: Malonyl-CoA
  Top 3 matches:
    Malonyl-CoA: 62.5%
    inactive: 58.3%
  minowa: Malonyl-CoA
  Prediction, score:
    Malonyl-CoA: 41.6
    Methoxymalonyl-CoA: 27.1
    inactive: 26.0
    Methylmalonyl-CoA: 20.3
    Propionyl-CoA: 15.2
    2-Methylbutyryl-CoA: 9.4
    trans-1,2-CPDA: 0.0
    fatty_acid: 0.0
    Isobutyryl-CoA: 0.0
    Ethylmalonyl-CoA: 0.0
    CHC-CoA: 0.0
    Benzoyl-CoA: 0.0
    Acetyl-CoA: 0.0
    3-Methylbutyryl-CoA: 0.0
ctg2_103: pk
  PKS_AT (9..302): pk
  ATSignature: (unknown)
  No matches above 50%
  minowa: trans-1,2-CPDA
  Prediction, score:
    trans-1,2-CPDA: 0.0
    inactive: 0.0
    fatty_acid: 0.0
    Propionyl-CoA: 0.0
    Methylmalonyl-CoA: 0.0
    Methoxymalonyl-CoA: 0.0
    Isobutyryl-CoA: 0.0
    Ethylmalonyl-CoA: 0.0
    CHC-CoA: 0.0
    Benzoyl-CoA: 0.0
    Acetyl-CoA: 0.0
    3-Methylbutyryl-CoA: 0.0
    2-Methylbutyryl-CoA: 0.0
    Malonyl-CoA: -1.6