GCF_003516165.1_ASM351616v1_genomic - 9 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP027798.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	NRPS	72,422	115,598	xantholipin	Polyketide	4%
Region 1.2	NRPS	1,457,499	1,501,253
Region 1.3	NRPS	2,147,412	2,193,947	pyrronazol B	NRP + Polyketide	9%
Region 1.4	redox-cofactor	2,213,809	2,234,868	lankacidin C	NRP + Polyketide	13%
Region 1.5	thiopeptide	2,987,155	3,013,599	O-antigen	Saccharide	14%
Region 1.6	prodigiosin	3,605,793	3,640,813	prodigiosin	Polyketide	100%
Region 1.7	redox-cofactor	3,793,379	3,815,541	lankacidin C	NRP + Polyketide	13%
Region 1.8	betalactone	3,986,079	4,011,749
Region 1.9	NRPS	4,400,917	4,460,758	vulnibactin	NRP	18%

No secondary metabolite regions were found in these records:: NZ_CP027799.1

Compact view

NZ_CP027798.1 - Region 1 - NRPS

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Location: 72,422 - 115,598 nt. (total: 43,177 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001615.1	0.34	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0000343.1	0.27	NRP	enterobactin	Pseudomonas sp. J465
BGC0000234.1	0.26	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0001833.1	0.26	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001149.1	0.25	NRP, Saccharide	brabantamide A	Pseudomonas sp. SHC52
BGC0001437.1	0.25	NRP	obafluorin	Pseudomonas fluorescens
BGC0001710.1	0.25	NRP	obafluorin	Pseudomonas fluorescens
BGC0001132.1	0.24	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001825.1	0.24	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001131.1	0.24	NRP	ambactin	Xenorhabdus miraniensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001615.1	0.67	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0000343.1	0.60	NRP	enterobactin	Pseudomonas sp. J465
BGC0000234.1	0.59	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0001833.1	0.59	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001149.1	0.58	NRP, Saccharide	brabantamide A	Pseudomonas sp. SHC52
BGC0001437.1	0.58	NRP	obafluorin	Pseudomonas fluorescens
BGC0001710.1	0.58	NRP	obafluorin	Pseudomonas fluorescens
BGC0001132.1	0.58	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001825.1	0.57	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001131.1	0.57	NRP	ambactin	Xenorhabdus miraniensis

Similar known gene clusters

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Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 72421 - 115598:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ser)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_74

Search NORINE for peptide: strict or relaxed

AMP-binding (464..869): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHMSLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

NZ_CP027798.1 - Region 2 - NRPS

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Location: 1,457,499 - 1,501,253 nt. (total: 43,755 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001479.1	0.27	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001399.1	0.25	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0001132.1	0.22	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001758.1	0.22	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001128.1	0.22	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000427.1	0.22	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001641.1	0.21	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001131.1	0.21	NRP	ambactin	Xenorhabdus miraniensis
BGC0000554.1	0.21	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0001825.1	0.21	NRP	xenematide	Xenorhabdus nematophila AN6/1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001479.1	0.60	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001399.1	0.58	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0001132.1	0.55	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001758.1	0.55	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001128.1	0.55	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000427.1	0.55	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001641.1	0.54	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001131.1	0.54	NRP	ambactin	Xenorhabdus miraniensis
BGC0000554.1	0.54	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0001825.1	0.53	NRP	xenematide	Xenorhabdus nematophila AN6/1

Similar known gene clusters

No matches found.

Module view

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Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 1457498 - 1501253:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-val)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_1339

Search NORINE for peptide: strict or relaxed

AMP-binding (442..849): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAfWLGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 90% (moderate)

NZ_CP027798.1 - Region 3 - NRPS

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Location: 2,147,412 - 2,193,947 nt. (total: 46,536 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001615.1	0.33	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0000410.1	0.28	NRP	pseudomonine	Pseudomonas fluorescens
BGC0000392.1	0.28	NRP	mirubactin	Actinosynnema mirum DSM 43827
BGC0001479.1	0.27	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001399.1	0.25	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000349.1	0.25	NRP	erythrochelin	Saccharopolyspora erythraea NRRL 2338
BGC0000343.1	0.25	NRP	enterobactin	Pseudomonas sp. J465
BGC0000426.1	0.25	NRP	sevadicin	Paenibacillus larvae
BGC0001437.1	0.24	NRP	obafluorin	Pseudomonas fluorescens
BGC0001710.1	0.24	NRP	obafluorin	Pseudomonas fluorescens

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001615.1	0.66	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0000410.1	0.62	NRP	pseudomonine	Pseudomonas fluorescens
BGC0000392.1	0.61	NRP	mirubactin	Actinosynnema mirum DSM 43827
BGC0001479.1	0.60	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001399.1	0.59	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000349.1	0.59	NRP	erythrochelin	Saccharopolyspora erythraea NRRL 2338
BGC0000343.1	0.58	NRP	enterobactin	Pseudomonas sp. J465
BGC0000426.1	0.58	NRP	sevadicin	Paenibacillus larvae
BGC0001437.1	0.57	NRP	obafluorin	Pseudomonas fluorescens
BGC0001710.1	0.57	NRP	obafluorin	Pseudomonas fluorescens

Similar known gene clusters

Module view

Legend

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 3, location 2147411 - 2193947:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-X - ser)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_1978

Search NORINE for peptide: strict or relaxed

AMP-binding (7..420): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: tFvavGGpVK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 50% (weak)

ctg1_1985

Search NORINE for peptide: strict or relaxed

AMP-binding (474..885): X

NRPSPredictor2: hydrophilic

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DSWdmGyVDK
Nearest Stachelhaus code:: asp
Stachelhaus code match:: 70% (weak)

AMP-binding (1990..2392): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

NZ_CP027798.1 - Region 4 - redox-cofactor

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Location: 2,213,809 - 2,234,868 nt. (total: 21,060 nt) Show pHMM detection rules used

redox-cofactor: (cds(PF04055 and (TIGR04085 or SPASM)) and (TIGR02111 or TIGR03966) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000859.1	0.26	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000854.1	0.26	Other	ectoine	Methylomicrobium alcaliphilum 20Z
BGC0000857.1	0.26	Other	ectoine	Methylophaga alcalica
BGC0000855.1	0.26	Other	ectoine	Methylomicrobium kenyense
BGC0000852.1	0.26	Other	ectoine	Sporosarcina pasteurii
BGC0000853.1	0.25	Other	ectoine	Streptomyces anulatus
BGC0000858.1	0.25	Other	ectoine	Methylobacter marinus
BGC0000856.1	0.25	Other	ectoine	Methylophaga thalassica
BGC0000860.1	0.25	Other	ectoine	Methylarcula marina
BGC0001478.1	0.17	Other	desferrioxamine E	Streptomyces sp. ID38640

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000859.1	0.59	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000854.1	0.59	Other	ectoine	Methylomicrobium alcaliphilum 20Z
BGC0000857.1	0.59	Other	ectoine	Methylophaga alcalica
BGC0000855.1	0.59	Other	ectoine	Methylomicrobium kenyense
BGC0000852.1	0.59	Other	ectoine	Sporosarcina pasteurii
BGC0000853.1	0.59	Other	ectoine	Streptomyces anulatus
BGC0000858.1	0.59	Other	ectoine	Methylobacter marinus
BGC0000856.1	0.59	Other	ectoine	Methylophaga thalassica
BGC0000860.1	0.58	Other	ectoine	Methylarcula marina
BGC0001478.1	0.49	Other	desferrioxamine E	Streptomyces sp. ID38640

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NZ_CP027798.1 - Region 5 - thiopeptide

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Location: 2,987,155 - 3,013,599 nt. (total: 26,445 nt) Show pHMM detection rules used

thiopeptide: ((YcaO or TIGR03882) and ((thio_amide and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N or PF07366 or PF06968 or PF04055) or thiostrepton)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Thiopeptides

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000784.1	0.26	Saccharide	O-antigen	Pseudomonas aeruginosa
BGC0000781.1	0.16	Saccharide	O-antigen	Pseudomonas aeruginosa
BGC0001285.1	0.07	Other (Fatty acid)	pseudopyronine A, pseudopyronine B	Pseudomonas putida
BGC0000981.1	0.06	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E6
BGC0001302.1	0.06	Other	lomofungin	Streptomyces lomondensis
BGC0002012.1	0.05	Polyketide	julichrome Q3-3, julichrome Q3-5	Streptomyces afghaniensis 772
BGC0001283.1	0.05	Polyketide	arsono-polyketide	Streptomyces lividans 1326
BGC0000957.1	0.04	NRP, Polyketide	mycotrienin I	Streptomyces sp. XZQH13
BGC0001448.1	0.03	NRP	malacidin A, malacidin B	uncultured bacterium
BGC0000123.1	0.03	Polyketide	phoslactomycin B	Streptomyces sp. HK803

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000784.1	0.59	Saccharide	O-antigen	Pseudomonas aeruginosa
BGC0000781.1	0.47	Saccharide	O-antigen	Pseudomonas aeruginosa
BGC0001285.1	0.29	Other (Fatty acid)	pseudopyronine A, pseudopyronine B	Pseudomonas putida
BGC0000981.1	0.24	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E6
BGC0001302.1	0.24	Other	lomofungin	Streptomyces lomondensis
BGC0002012.1	0.23	Polyketide	julichrome Q3-3, julichrome Q3-5	Streptomyces afghaniensis 772
BGC0001283.1	0.22	Polyketide	arsono-polyketide	Streptomyces lividans 1326
BGC0000957.1	0.19	NRP, Polyketide	mycotrienin I	Streptomyces sp. XZQH13
BGC0001448.1	0.17	NRP	malacidin A, malacidin B	uncultured bacterium
BGC0000123.1	0.15	Polyketide	phoslactomycin B	Streptomyces sp. HK803

Similar known gene clusters

Thiopeptide predictions

No core peptides found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

Thiopeptides

Core peptide predictions

No core peptides found.

NZ_CP027798.1 - Region 6 - prodigiosin

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Location: 3,605,793 - 3,640,813 nt. (total: 35,021 nt) Show pHMM detection rules used

prodigiosin: (PPDK_N and AMP-binding and PP-binding and PKS_KS)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000259.1	0.81	Polyketide	prodigiosin	Serratia marcescens
BGC0000258.1	0.50	Polyketide	prodigiosin	Serratia sp.
BGC0000260.1	0.27	Polyketide	prodigiosin	Hahella chejuensis KCTC 2396
BGC0000857.1	0.24	Other	ectoine	Methylophaga alcalica
BGC0000858.1	0.24	Other	ectoine	Methylobacter marinus
BGC0000859.1	0.24	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000854.1	0.24	Other	ectoine	Methylomicrobium alcaliphilum 20Z
BGC0000853.1	0.24	Other	ectoine	Streptomyces anulatus
BGC0000852.1	0.24	Other	ectoine	Sporosarcina pasteurii
BGC0000860.1	0.24	Other	ectoine	Methylarcula marina

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000259.1	0.93	Polyketide	prodigiosin	Serratia marcescens
BGC0000258.1	0.79	Polyketide	prodigiosin	Serratia sp.
BGC0000260.1	0.60	Polyketide	prodigiosin	Hahella chejuensis KCTC 2396
BGC0000857.1	0.58	Other	ectoine	Methylophaga alcalica
BGC0000858.1	0.58	Other	ectoine	Methylobacter marinus
BGC0000859.1	0.58	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000854.1	0.58	Other	ectoine	Methylomicrobium alcaliphilum 20Z
BGC0000853.1	0.58	Other	ectoine	Streptomyces anulatus
BGC0000852.1	0.57	Other	ectoine	Sporosarcina pasteurii
BGC0000860.1	0.57	Other	ectoine	Methylarcula marina

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NZ_CP027798.1 - Region 7 - redox-cofactor

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Location: 3,793,379 - 3,815,541 nt. (total: 22,163 nt) Show pHMM detection rules used

redox-cofactor: (cds(PF04055 and (TIGR04085 or SPASM)) and (TIGR02111 or TIGR03966) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000703.1	0.14	Saccharide	kanamycin	Streptomyces kanamyceticus
BGC0000883.1	0.13	Other	arginomycin	Streptomyces arginensis
BGC0001100.1	0.09	NRP, Polyketide	lankacidin C	Streptomyces rochei
BGC0000453.1	0.07	NRP	valinomycin	Streptomyces tsusimaensis
BGC0001127.1	0.07	NRP	jagaricin	Janthinobacterium agaricidamnosum
BGC0002007.1	0.06	Terpene	atolypene A, atolypene B	Amycolatopsis tolypomycina
BGC0001750.1	0.06	NRP, Polyketide	pyrronazol B	Nannocystis pusilla
BGC0000433.1	0.06	NRP	surfactin	Bacillus velezensis FZB42
BGC0001199.1	0.05	Polyketide	akaeolide	Streptomyces sp. NBRC 109706
BGC0001769.1	0.05	Polyketide	saquayamycin A	Streptomyces sp.

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000703.1	0.44	Saccharide	kanamycin	Streptomyces kanamyceticus
BGC0000883.1	0.41	Other	arginomycin	Streptomyces arginensis
BGC0001100.1	0.34	NRP, Polyketide	lankacidin C	Streptomyces rochei
BGC0000453.1	0.29	NRP	valinomycin	Streptomyces tsusimaensis
BGC0001127.1	0.29	NRP	jagaricin	Janthinobacterium agaricidamnosum
BGC0002007.1	0.26	Terpene	atolypene A, atolypene B	Amycolatopsis tolypomycina
BGC0001750.1	0.25	NRP, Polyketide	pyrronazol B	Nannocystis pusilla
BGC0000433.1	0.24	NRP	surfactin	Bacillus velezensis FZB42
BGC0001199.1	0.24	Polyketide	akaeolide	Streptomyces sp. NBRC 109706
BGC0001769.1	0.24	Polyketide	saquayamycin A	Streptomyces sp.

Similar known gene clusters

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NZ_CP027798.1 - Region 8 - betalactone

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Location: 3,986,079 - 4,011,749 nt. (total: 25,671 nt) Show pHMM detection rules used

betalactone: (HMGL-like and AMP-binding)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001859.1	0.20	Other (Phosphonate)	fosfomycin	Pseudomonas syringae
BGC0000904.1	0.16	Other	FR-900098	Streptomyces rubellomurinus
BGC0000375.1	0.15	NRP	indigoidine	Streptomyces chromofuscus
BGC0001441.1	0.14	Other	belactosin A, belactosin C	Streptomyces sp.
BGC0001135.1	0.14	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0000597.1	0.13	RiPP	SWA-2138	Streptomyces sp. e14
BGC0000805.1	0.13	Saccharide	moenomycin	Streptomyces viridosporus ATCC 14672
BGC0000595.1	0.13	RiPP	SCO-2138	Streptomyces coelicolor A3(2)
BGC0000596.1	0.13	RiPP	SLI-2138	Streptomyces lividans TK24
BGC0000207.1	0.13	Polyketide	chartreusin	Streptomyces chartreusis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001859.1	0.52	Other (Phosphonate)	fosfomycin	Pseudomonas syringae
BGC0000904.1	0.46	Other	FR-900098	Streptomyces rubellomurinus
BGC0000375.1	0.46	NRP	indigoidine	Streptomyces chromofuscus
BGC0001441.1	0.44	Other	belactosin A, belactosin C	Streptomyces sp.
BGC0001135.1	0.43	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0000597.1	0.42	RiPP	SWA-2138	Streptomyces sp. e14
BGC0000805.1	0.42	Saccharide	moenomycin	Streptomyces viridosporus ATCC 14672
BGC0000595.1	0.41	RiPP	SCO-2138	Streptomyces coelicolor A3(2)
BGC0000596.1	0.41	RiPP	SLI-2138	Streptomyces lividans TK24
BGC0000207.1	0.41	Polyketide	chartreusin	Streptomyces chartreusis

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NZ_CP027798.1 - Region 9 - NRPS

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Location: 4,400,917 - 4,460,758 nt. (total: 59,842 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

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Gene details

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NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001615.1	0.32	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0001185.1	0.31	NRP	bacillibactin	Bacillus velezensis FZB42
BGC0000401.1	0.27	NRP	paenibactin	Paenibacillus elgii B69
BGC0000426.1	0.25	NRP	sevadicin	Paenibacillus larvae
BGC0001132.1	0.25	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001833.1	0.25	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0000389.1	0.25	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0000454.1	0.25	NRP	vanchrobactin	Vibrio anguillarum RV22
BGC0000465.1	0.25	NRP	xenortide A, xenortide B, xenortide C, xenortide D	Xenorhabdus nematophila ATCC 19061
BGC0001844.1	0.24	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001615.1	0.65	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0001185.1	0.65	NRP	bacillibactin	Bacillus velezensis FZB42
BGC0000401.1	0.61	NRP	paenibactin	Paenibacillus elgii B69
BGC0000426.1	0.59	NRP	sevadicin	Paenibacillus larvae
BGC0001132.1	0.58	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001833.1	0.58	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0000389.1	0.58	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0000454.1	0.58	NRP	vanchrobactin	Vibrio anguillarum RV22
BGC0000465.1	0.58	NRP	xenortide A, xenortide B, xenortide C, xenortide D	Xenorhabdus nematophila ATCC 19061
BGC0001844.1	0.57	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454

Similar known gene clusters

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 9, location 4400916 - 4460758:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ser)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_4110

Search NORINE for peptide: strict or relaxed

AMP-binding (32..438): dhb

NRPSPredictor2: dhb

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: dhb, sal
Small clusters prediction:: dhb, sal
Single AA prediction:: dhb

Stachelhaus prediction details:

Stachelhaus sequence:: PMPAQGVVNK
Nearest Stachelhaus code:: dhb
Stachelhaus code match:: 100% (strong)

ctg1_4113

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AMP-binding (475..877): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

ctg1_4121

Search NORINE for peptide: strict or relaxed

AMP-binding (454..843): thr

NRPSPredictor2: thr

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DMFcAGLIWK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 90% (moderate)

ctg1_4124

Search NORINE for peptide: strict or relaxed

AMP-binding (82..522): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: vtyYiGkIvK
Nearest Stachelhaus code:: orn
Stachelhaus code match:: 40% (weak)