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Overview
1.1
1.2
1.3
1.4
1.5
1.6
1.7
1.8
1.9

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP027798.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | NRPS | 72,422 | 115,598 | xantholipin | Polyketide | 4%
Region 1.2 | NRPS | 1,457,499 | 1,501,253 |
Region 1.3 | NRPS | 2,147,412 | 2,193,947 | pyrronazol B | NRP + Polyketide | 9%
Region 1.4 | redox-cofactor | 2,213,809 | 2,234,868 | lankacidin C | NRP + Polyketide | 13%
Region 1.5 | thiopeptide | 2,987,155 | 3,013,599 | O-antigen | Saccharide | 14%
Region 1.6 | prodigiosin | 3,605,793 | 3,640,813 | prodigiosin | Polyketide | 100%
Region 1.7 | redox-cofactor | 3,793,379 | 3,815,541 | lankacidin C | NRP + Polyketide | 13%
Region 1.8 | betalactone | 3,986,079 | 4,011,749 |
Region 1.9 | NRPS | 4,400,917 | 4,460,758 | vulnibactin | NRP | 18%

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | NRPS | 72,422 | 115,598 | xantholipin | Polyketide | 4%
Region 1.2 | NRPS | 1,457,499 | 1,501,253 |
Region 1.3 | NRPS | 2,147,412 | 2,193,947 | pyrronazol B | NRP + Polyketide | 9%
Region 1.4 | redox-cofactor | 2,213,809 | 2,234,868 | lankacidin C | NRP + Polyketide | 13%
Region 1.5 | thiopeptide | 2,987,155 | 3,013,599 | O-antigen | Saccharide | 14%
Region 1.6 | prodigiosin | 3,605,793 | 3,640,813 | prodigiosin | Polyketide | 100%
Region 1.7 | redox-cofactor | 3,793,379 | 3,815,541 | lankacidin C | NRP + Polyketide | 13%
Region 1.8 | betalactone | 3,986,079 | 4,011,749 |
Region 1.9 | NRPS | 4,400,917 | 4,460,758 | vulnibactin | NRP | 18%

No secondary metabolite regions were found in these records:
  NZ_CP027799.1

Compact view
NZ_CP027798.1 - Region 1 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 72,422 - 115,598 nt. (total: 43,177 nt) Show pHMM detection rules used
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001615.1 |  | 0.34 | NRP | hexose-palythine-serine, hexose-shinorine | Heteroscytonema crispum UCFS10
BGC0000343.1 |  | 0.27 | NRP | enterobactin | Pseudomonas sp. J465
BGC0000234.1 |  | 0.26 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0001833.1 |  | 0.26 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001149.1 |  | 0.25 | NRP, Saccharide | brabantamide A | Pseudomonas sp. SHC52
BGC0001437.1 |  | 0.25 | NRP | obafluorin | Pseudomonas fluorescens
BGC0001710.1 |  | 0.25 | NRP | obafluorin | Pseudomonas fluorescens
BGC0001132.1 |  | 0.24 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001825.1 |  | 0.24 | NRP | xenematide | Xenorhabdus nematophila AN6/1
BGC0001131.1 |  | 0.24 | NRP | ambactin | Xenorhabdus miraniensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001615.1 |  | 0.67 | NRP | hexose-palythine-serine, hexose-shinorine | Heteroscytonema crispum UCFS10
BGC0000343.1 |  | 0.60 | NRP | enterobactin | Pseudomonas sp. J465
BGC0000234.1 |  | 0.59 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0001833.1 |  | 0.59 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001149.1 |  | 0.58 | NRP, Saccharide | brabantamide A | Pseudomonas sp. SHC52
BGC0001437.1 |  | 0.58 | NRP | obafluorin | Pseudomonas fluorescens
BGC0001710.1 |  | 0.58 | NRP | obafluorin | Pseudomonas fluorescens
BGC0001132.1 |  | 0.58 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001825.1 |  | 0.57 | NRP | xenematide | Xenorhabdus nematophila AN6/1
BGC0001131.1 |  | 0.57 | NRP | ambactin | Xenorhabdus miraniensis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 72421 - 115598:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (ser)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_74: ser
  Search NORINE for peptide: strict or relaxed
  AMP-binding (464..869): ser
  NRPSPredictor2: ser
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      ser, thr, dhpg, hpg
    Small clusters prediction:
      ser
    Single AA prediction:
      ser
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVWHMSLVDK
    Nearest Stachelhaus code:
      ser
    Stachelhaus code match:
      100% (strong)

NZ_CP027798.1 - Region 2 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,457,499 - 1,501,253 nt. (total: 43,755 nt) Show pHMM detection rules used
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001479.1 |  | 0.27 | NRP | anabaenopeptin NZ857, nostamide A | Nostoc punctiforme PCC 73102
BGC0001399.1 |  | 0.25 | NRP | fellutamide B | Aspergillus nidulans FGSC A4
BGC0001132.1 |  | 0.22 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001758.1 |  | 0.22 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001128.1 |  | 0.22 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0000427.1 |  | 0.22 | NRP | shinorine, 4-deoxygadusol, mycosporine glycine | Trichormus variabilis ATCC 29413
BGC0001641.1 |  | 0.21 | NRP | kolossin | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001131.1 |  | 0.21 | NRP | ambactin | Xenorhabdus miraniensis
BGC0000554.1 |  | 0.21 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0001825.1 |  | 0.21 | NRP | xenematide | Xenorhabdus nematophila AN6/1

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001479.1 |  | 0.60 | NRP | anabaenopeptin NZ857, nostamide A | Nostoc punctiforme PCC 73102
BGC0001399.1 |  | 0.58 | NRP | fellutamide B | Aspergillus nidulans FGSC A4
BGC0001132.1 |  | 0.55 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001758.1 |  | 0.55 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001128.1 |  | 0.55 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0000427.1 |  | 0.55 | NRP | shinorine, 4-deoxygadusol, mycosporine glycine | Trichormus variabilis ATCC 29413
BGC0001641.1 |  | 0.54 | NRP | kolossin | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001131.1 |  | 0.54 | NRP | ambactin | Xenorhabdus miraniensis
BGC0000554.1 |  | 0.54 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0001825.1 |  | 0.53 | NRP | xenematide | Xenorhabdus nematophila AN6/1

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 1457498 - 1501253:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (D-val)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_1339: val
  Search NORINE for peptide: strict or relaxed
  AMP-binding (442..849): val
  NRPSPredictor2: val
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      gly, ala, val, leu, ile, abu, iva
    Small clusters prediction:
      val, leu, ile, abu, iva
    Single AA prediction:
      val
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAfWLGGTFK
    Nearest Stachelhaus code:
      val
    Stachelhaus code match:
      90% (moderate)

NZ_CP027798.1 - Region 3 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,147,412 - 2,193,947 nt. (total: 46,536 nt) Show pHMM detection rules used
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001615.1 |  | 0.33 | NRP | hexose-palythine-serine, hexose-shinorine | Heteroscytonema crispum UCFS10
BGC0000410.1 |  | 0.28 | NRP | pseudomonine | Pseudomonas fluorescens
BGC0000392.1 |  | 0.28 | NRP | mirubactin | Actinosynnema mirum DSM 43827
BGC0001479.1 |  | 0.27 | NRP | anabaenopeptin NZ857, nostamide A | Nostoc punctiforme PCC 73102
BGC0001399.1 |  | 0.25 | NRP | fellutamide B | Aspergillus nidulans FGSC A4
BGC0000349.1 |  | 0.25 | NRP | erythrochelin | Saccharopolyspora erythraea NRRL 2338
BGC0000343.1 |  | 0.25 | NRP | enterobactin | Pseudomonas sp. J465
BGC0000426.1 |  | 0.25 | NRP | sevadicin | Paenibacillus larvae
BGC0001437.1 |  | 0.24 | NRP | obafluorin | Pseudomonas fluorescens
BGC0001710.1 |  | 0.24 | NRP | obafluorin | Pseudomonas fluorescens

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001615.1 |  | 0.66 | NRP | hexose-palythine-serine, hexose-shinorine | Heteroscytonema crispum UCFS10
BGC0000410.1 |  | 0.62 | NRP | pseudomonine | Pseudomonas fluorescens
BGC0000392.1 |  | 0.61 | NRP | mirubactin | Actinosynnema mirum DSM 43827
BGC0001479.1 |  | 0.60 | NRP | anabaenopeptin NZ857, nostamide A | Nostoc punctiforme PCC 73102
BGC0001399.1 |  | 0.59 | NRP | fellutamide B | Aspergillus nidulans FGSC A4
BGC0000349.1 |  | 0.59 | NRP | erythrochelin | Saccharopolyspora erythraea NRRL 2338
BGC0000343.1 |  | 0.58 | NRP | enterobactin | Pseudomonas sp. J465
BGC0000426.1 |  | 0.58 | NRP | sevadicin | Paenibacillus larvae
BGC0001437.1 |  | 0.57 | NRP | obafluorin | Pseudomonas fluorescens
BGC0001710.1 |  | 0.57 | NRP | obafluorin | Pseudomonas fluorescens

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 2147411 - 2193947:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (D-X - ser)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_1978: X
  Search NORINE for peptide: strict or relaxed
  AMP-binding (7..420): X
  NRPSPredictor2: (unknown)
  SVM prediction details:
    NOTE: outside applicability domain
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      N/A
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      tFvavGGpVK
    Nearest Stachelhaus code:
      leu
    Stachelhaus code match:
      50% (weak)
ctg1_1985: X - ser
  Search NORINE for peptide: strict or relaxed
  AMP-binding (474..885): X
  NRPSPredictor2: hydrophilic
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      N/A
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DSWdmGyVDK
    Nearest Stachelhaus code:
      asp
    Stachelhaus code match:
      70% (weak)
  AMP-binding (1990..2392): ser
  NRPSPredictor2: ser
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      ser, thr, dhpg, hpg
    Small clusters prediction:
      ser
    Single AA prediction:
      ser
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVWHFSLVDK
    Nearest Stachelhaus code:
      ser
    Stachelhaus code match:
      100% (strong)

NZ_CP027798.1 - Region 4 - redox-cofactor
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,213,809 - 2,234,868 nt. (total: 21,060 nt) Show pHMM detection rules used
redox-cofactor: (cds(PF04055 and (TIGR04085 or SPASM)) and (TIGR02111 or TIGR03966) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | redox-cofactor | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000859.1 |  | 0.26 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000854.1 |  | 0.26 | Other | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0000857.1 |  | 0.26 | Other | ectoine | Methylophaga alcalica
BGC0000855.1 |  | 0.26 | Other | ectoine | Methylomicrobium kenyense
BGC0000852.1 |  | 0.26 | Other | ectoine | Sporosarcina pasteurii
BGC0000853.1 |  | 0.25 | Other | ectoine | Streptomyces anulatus
BGC0000858.1 |  | 0.25 | Other | ectoine | Methylobacter marinus
BGC0000856.1 |  | 0.25 | Other | ectoine | Methylophaga thalassica
BGC0000860.1 |  | 0.25 | Other | ectoine | Methylarcula marina
BGC0001478.1 |  | 0.17 | Other | desferrioxamine E | Streptomyces sp. ID38640

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000859.1 |  | 0.59 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000854.1 |  | 0.59 | Other | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0000857.1 |  | 0.59 | Other | ectoine | Methylophaga alcalica
BGC0000855.1 |  | 0.59 | Other | ectoine | Methylomicrobium kenyense
BGC0000852.1 |  | 0.59 | Other | ectoine | Sporosarcina pasteurii
BGC0000853.1 |  | 0.59 | Other | ectoine | Streptomyces anulatus
BGC0000858.1 |  | 0.59 | Other | ectoine | Methylobacter marinus
BGC0000856.1 |  | 0.59 | Other | ectoine | Methylophaga thalassica
BGC0000860.1 |  | 0.58 | Other | ectoine | Methylarcula marina
BGC0001478.1 |  | 0.49 | Other | desferrioxamine E | Streptomyces sp. ID38640

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP027798.1 - Region 5 - thiopeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
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Location: 2,987,155 - 3,013,599 nt. (total: 26,445 nt) Show pHMM detection rules used
thiopeptide: ((YcaO or TIGR03882) and ((thio_amide and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N or PF07366 or PF06968 or PF04055) or thiostrepton)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Thiopeptides
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | thiopeptide | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000784.1 |  | 0.26 | Saccharide | O-antigen | Pseudomonas aeruginosa
BGC0000781.1 |  | 0.16 | Saccharide | O-antigen | Pseudomonas aeruginosa
BGC0001285.1 |  | 0.07 | Other (Fatty acid) | pseudopyronine A, pseudopyronine B | Pseudomonas putida
BGC0000981.1 |  | 0.06 | NRP, Polyketide | cylindrospermopsin | Aphanizomenon sp. 10E6
BGC0001302.1 |  | 0.06 | Other | lomofungin | Streptomyces lomondensis
BGC0002012.1 |  | 0.05 | Polyketide | julichrome Q3-3, julichrome Q3-5 | Streptomyces afghaniensis 772
BGC0001283.1 |  | 0.05 | Polyketide | arsono-polyketide | Streptomyces lividans 1326
BGC0000957.1 |  | 0.04 | NRP, Polyketide | mycotrienin I | Streptomyces sp. XZQH13
BGC0001448.1 |  | 0.03 | NRP | malacidin A, malacidin B | uncultured bacterium
BGC0000123.1 |  | 0.03 | Polyketide | phoslactomycin B | Streptomyces sp. HK803

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000784.1 |  | 0.59 | Saccharide | O-antigen | Pseudomonas aeruginosa
BGC0000781.1 |  | 0.47 | Saccharide | O-antigen | Pseudomonas aeruginosa
BGC0001285.1 |  | 0.29 | Other (Fatty acid) | pseudopyronine A, pseudopyronine B | Pseudomonas putida
BGC0000981.1 |  | 0.24 | NRP, Polyketide | cylindrospermopsin | Aphanizomenon sp. 10E6
BGC0001302.1 |  | 0.24 | Other | lomofungin | Streptomyces lomondensis
BGC0002012.1 |  | 0.23 | Polyketide | julichrome Q3-3, julichrome Q3-5 | Streptomyces afghaniensis 772
BGC0001283.1 |  | 0.22 | Polyketide | arsono-polyketide | Streptomyces lividans 1326
BGC0000957.1 |  | 0.19 | NRP, Polyketide | mycotrienin I | Streptomyces sp. XZQH13
BGC0001448.1 |  | 0.17 | NRP | malacidin A, malacidin B | uncultured bacterium
BGC0000123.1 |  | 0.15 | Polyketide | phoslactomycin B | Streptomyces sp. HK803

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Thiopeptide predictions
Lists the possible core peptides for each biosynthetic enzyme, including the predicted class. Each core peptide shows the leader and core peptide sequences, separated by a dash. Predicted tail sequences are also shown.
No core peptides found.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
Thiopeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists its possible molecular weights and the scores for cleavage site prediction and RODEO. If relevant, other features, such as macrocycle and amidation, will also be listed.
No core peptides found.
NZ_CP027798.1 - Region 6 - prodigiosin
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,605,793 - 3,640,813 nt. (total: 35,021 nt) Show pHMM detection rules used
prodigiosin: (PPDK_N and AMP-binding and PP-binding and PKS_KS)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | prodigiosin | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000259.1 |  | 0.81 | Polyketide | prodigiosin | Serratia marcescens
BGC0000258.1 |  | 0.50 | Polyketide | prodigiosin | Serratia sp.
BGC0000260.1 |  | 0.27 | Polyketide | prodigiosin | Hahella chejuensis KCTC 2396
BGC0000857.1 |  | 0.24 | Other | ectoine | Methylophaga alcalica
BGC0000858.1 |  | 0.24 | Other | ectoine | Methylobacter marinus
BGC0000859.1 |  | 0.24 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000854.1 |  | 0.24 | Other | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0000853.1 |  | 0.24 | Other | ectoine | Streptomyces anulatus
BGC0000852.1 |  | 0.24 | Other | ectoine | Sporosarcina pasteurii
BGC0000860.1 |  | 0.24 | Other | ectoine | Methylarcula marina

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000259.1 |  | 0.93 | Polyketide | prodigiosin | Serratia marcescens
BGC0000258.1 |  | 0.79 | Polyketide | prodigiosin | Serratia sp.
BGC0000260.1 |  | 0.60 | Polyketide | prodigiosin | Hahella chejuensis KCTC 2396
BGC0000857.1 |  | 0.58 | Other | ectoine | Methylophaga alcalica
BGC0000858.1 |  | 0.58 | Other | ectoine | Methylobacter marinus
BGC0000859.1 |  | 0.58 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000854.1 |  | 0.58 | Other | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0000853.1 |  | 0.58 | Other | ectoine | Streptomyces anulatus
BGC0000852.1 |  | 0.57 | Other | ectoine | Sporosarcina pasteurii
BGC0000860.1 |  | 0.57 | Other | ectoine | Methylarcula marina

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP027798.1 - Region 7 - redox-cofactor
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
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Location: 3,793,379 - 3,815,541 nt. (total: 22,163 nt) Show pHMM detection rules used
redox-cofactor: (cds(PF04055 and (TIGR04085 or SPASM)) and (TIGR02111 or TIGR03966) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | redox-cofactor | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000703.1 |  | 0.14 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0000883.1 |  | 0.13 | Other | arginomycin | Streptomyces arginensis
BGC0001100.1 |  | 0.09 | NRP, Polyketide | lankacidin C | Streptomyces rochei
BGC0000453.1 |  | 0.07 | NRP | valinomycin | Streptomyces tsusimaensis
BGC0001127.1 |  | 0.07 | NRP | jagaricin | Janthinobacterium agaricidamnosum
BGC0002007.1 |  | 0.06 | Terpene | atolypene A, atolypene B | Amycolatopsis tolypomycina
BGC0001750.1 |  | 0.06 | NRP, Polyketide | pyrronazol B | Nannocystis pusilla
BGC0000433.1 |  | 0.06 | NRP | surfactin | Bacillus velezensis FZB42
BGC0001199.1 |  | 0.05 | Polyketide | akaeolide | Streptomyces sp. NBRC 109706
BGC0001769.1 |  | 0.05 | Polyketide | saquayamycin A | Streptomyces sp.

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000703.1 |  | 0.44 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0000883.1 |  | 0.41 | Other | arginomycin | Streptomyces arginensis
BGC0001100.1 |  | 0.34 | NRP, Polyketide | lankacidin C | Streptomyces rochei
BGC0000453.1 |  | 0.29 | NRP | valinomycin | Streptomyces tsusimaensis
BGC0001127.1 |  | 0.29 | NRP | jagaricin | Janthinobacterium agaricidamnosum
BGC0002007.1 |  | 0.26 | Terpene | atolypene A, atolypene B | Amycolatopsis tolypomycina
BGC0001750.1 |  | 0.25 | NRP, Polyketide | pyrronazol B | Nannocystis pusilla
BGC0000433.1 |  | 0.24 | NRP | surfactin | Bacillus velezensis FZB42
BGC0001199.1 |  | 0.24 | Polyketide | akaeolide | Streptomyces sp. NBRC 109706
BGC0001769.1 |  | 0.24 | Polyketide | saquayamycin A | Streptomyces sp.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP027798.1 - Region 8 - betalactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,986,079 - 4,011,749 nt. (total: 25,671 nt) Show pHMM detection rules used
betalactone: (HMGL-like and AMP-binding)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | betalactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001859.1 |  | 0.20 | Other (Phosphonate) | fosfomycin | Pseudomonas syringae
BGC0000904.1 |  | 0.16 | Other | FR-900098 | Streptomyces rubellomurinus
BGC0000375.1 |  | 0.15 | NRP | indigoidine | Streptomyces chromofuscus
BGC0001441.1 |  | 0.14 | Other | belactosin A, belactosin C | Streptomyces sp.
BGC0001135.1 |  | 0.14 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0000597.1 |  | 0.13 | RiPP | SWA-2138 | Streptomyces sp. e14
BGC0000805.1 |  | 0.13 | Saccharide | moenomycin | Streptomyces viridosporus ATCC 14672
BGC0000595.1 |  | 0.13 | RiPP | SCO-2138 | Streptomyces coelicolor A3(2)
BGC0000596.1 |  | 0.13 | RiPP | SLI-2138 | Streptomyces lividans TK24
BGC0000207.1 |  | 0.13 | Polyketide | chartreusin | Streptomyces chartreusis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001859.1 |  | 0.52 | Other (Phosphonate) | fosfomycin | Pseudomonas syringae
BGC0000904.1 |  | 0.46 | Other | FR-900098 | Streptomyces rubellomurinus
BGC0000375.1 |  | 0.46 | NRP | indigoidine | Streptomyces chromofuscus
BGC0001441.1 |  | 0.44 | Other | belactosin A, belactosin C | Streptomyces sp.
BGC0001135.1 |  | 0.43 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0000597.1 |  | 0.42 | RiPP | SWA-2138 | Streptomyces sp. e14
BGC0000805.1 |  | 0.42 | Saccharide | moenomycin | Streptomyces viridosporus ATCC 14672
BGC0000595.1 |  | 0.41 | RiPP | SCO-2138 | Streptomyces coelicolor A3(2)
BGC0000596.1 |  | 0.41 | RiPP | SLI-2138 | Streptomyces lividans TK24
BGC0000207.1 |  | 0.41 | Polyketide | chartreusin | Streptomyces chartreusis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP027798.1 - Region 9 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 4,400,917 - 4,460,758 nt. (total: 59,842 nt) Show pHMM detection rules used
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001615.1 |  | 0.32 | NRP | hexose-palythine-serine, hexose-shinorine | Heteroscytonema crispum UCFS10
BGC0001185.1 |  | 0.31 | NRP | bacillibactin | Bacillus velezensis FZB42
BGC0000401.1 |  | 0.27 | NRP | paenibactin | Paenibacillus elgii B69
BGC0000426.1 |  | 0.25 | NRP | sevadicin | Paenibacillus larvae
BGC0001132.1 |  | 0.25 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001833.1 |  | 0.25 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0000389.1 |  | 0.25 | NRP | massetolide A | Pseudomonas fluorescens SS101
BGC0000454.1 |  | 0.25 | NRP | vanchrobactin | Vibrio anguillarum RV22
BGC0000465.1 |  | 0.25 | NRP | xenortide A, xenortide B, xenortide C, xenortide D | Xenorhabdus nematophila ATCC 19061
BGC0001844.1 |  | 0.24 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001615.1 |  | 0.65 | NRP | hexose-palythine-serine, hexose-shinorine | Heteroscytonema crispum UCFS10
BGC0001185.1 |  | 0.65 | NRP | bacillibactin | Bacillus velezensis FZB42
BGC0000401.1 |  | 0.61 | NRP | paenibactin | Paenibacillus elgii B69
BGC0000426.1 |  | 0.59 | NRP | sevadicin | Paenibacillus larvae
BGC0001132.1 |  | 0.58 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001833.1 |  | 0.58 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0000389.1 |  | 0.58 | NRP | massetolide A | Pseudomonas fluorescens SS101
BGC0000454.1 |  | 0.58 | NRP | vanchrobactin | Vibrio anguillarum RV22
BGC0000465.1 |  | 0.58 | NRP | xenortide A, xenortide B, xenortide C, xenortide D | Xenorhabdus nematophila ATCC 19061
BGC0001844.1 |  | 0.57 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 9, location 4400916 - 4460758:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (ser)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_4110: dhb
  Search NORINE for peptide: strict or relaxed
  AMP-binding (32..438): dhb
  NRPSPredictor2: dhb
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aromatic
    Large clusters prediction:
      dhb, sal
    Small clusters prediction:
      dhb, sal
    Single AA prediction:
      dhb
  Stachelhaus prediction details:
    Stachelhaus sequence:
      PMPAQGVVNK
    Nearest Stachelhaus code:
      dhb
    Stachelhaus code match:
      100% (strong)
ctg1_4113: ser
  Search NORINE for peptide: strict or relaxed
  AMP-binding (475..877): ser
  NRPSPredictor2: ser
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      ser, thr, dhpg, hpg
    Small clusters prediction:
      ser
    Single AA prediction:
      ser
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVWHFSLVDK
    Nearest Stachelhaus code:
      ser
    Stachelhaus code match:
      100% (strong)
ctg1_4121: thr
  Search NORINE for peptide: strict or relaxed
  AMP-binding (454..843): thr
  NRPSPredictor2: thr
  SVM prediction details:
    NOTE: outside applicability domain
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      ser, thr, dhpg, hpg
    Small clusters prediction:
      thr
    Single AA prediction:
      thr
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DMFcAGLIWK
    Nearest Stachelhaus code:
      thr
    Stachelhaus code match:
      90% (moderate)
ctg1_4124: X
  Search NORINE for peptide: strict or relaxed
  AMP-binding (82..522): X
  NRPSPredictor2: (unknown)
  SVM prediction details:
    NOTE: outside applicability domain
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      asp, asn, glu, gln, aad
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      vtyYiGkIvK
    Nearest Stachelhaus code:
      orn
    Stachelhaus code match:
      40% (weak)