GCF_000233595.1_ASM23359v1_genomic - 8 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NC_017554.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	hserlactone	2,323,536	2,342,702
Region 1.2	redox-cofactor	2,430,510	2,452,675	lankacidin C	NRP + Polyketide	13%
Region 1.3	hserlactone	2,937,749	2,958,360
Region 1.4	thiopeptide	3,017,908	3,044,173	O-antigen	Saccharide	14%
Region 1.5	siderophore	3,857,506	3,868,860	desferrioxamine E	Other	100%
Region 1.6	phosphonate,butyrolactone	4,129,395	4,170,321
Region 1.7	siderophore	4,256,841	4,271,246	aerobactin	Other	77%

NC_017553.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 2.1	terpene	248,680	272,244	carotenoid	Terpene	100%

Region	Type	From	To	Most similar known cluster	Similarity
Region 1.1	hserlactone	2,323,536	2,342,702
Region 1.2	redox-cofactor	2,430,510	2,452,675	lankacidin C	NRP + Polyketide	13%
Region 1.3	hserlactone	2,937,749	2,958,360
Region 1.4	thiopeptide	3,017,908	3,044,173	O-antigen	Saccharide	14%
Region 1.5	siderophore	3,857,506	3,868,860	desferrioxamine E	Other	100%
Region 1.6	phosphonate,butyrolactone	4,129,395	4,170,321
Region 1.7	siderophore	4,256,841	4,271,246	aerobactin	Other	77%
Region 2.1	terpene	248,680	272,244	carotenoid	Terpene	100%

Compact view

NC_017554.1 - Region 1 - hserlactone

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Location: 2,323,536 - 2,342,702 nt. (total: 19,167 nt) Show pHMM detection rules used

hserlactone: Autoind_synth

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001184.1	0.15	Other	bacilysin	Bacillus velezensis FZB42
BGC0000243.1	0.15	Polyketide	macrotetrolide	Streptomyces griseus subsp. griseus
BGC0001928.1	0.14	Other	(2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid	Streptomyces sp. MA37
BGC0001605.1	0.14	Terpene	gibberellin	Sinorhizobium fredii NGR234
BGC0001197.1	0.14	Polyketide	frankiamicin	Frankia sp. EAN1pec
BGC0001987.1	0.14	Polyketide	koreenceine A, koreenceine B, koreenceine C, koreenceine D	Pseudomonas koreensis
BGC0001882.1	0.14	Polyketide	chrysoxanthone A, chrysoxanthone B, chrysoxanthone C	Penicillium rubens Wisconsin 54-1255
BGC0000899.1	0.14	Other	desosamine	Streptomyces narbonensis
BGC0001156.1	0.14	Terpene	platencin	Streptomyces platensis
BGC0001783.1	0.14	Other	streptonigrin	Streptomyces flocculus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001184.1	0.45	Other	bacilysin	Bacillus velezensis FZB42
BGC0000243.1	0.44	Polyketide	macrotetrolide	Streptomyces griseus subsp. griseus
BGC0001928.1	0.44	Other	(2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid	Streptomyces sp. MA37
BGC0001605.1	0.44	Terpene	gibberellin	Sinorhizobium fredii NGR234
BGC0001197.1	0.44	Polyketide	frankiamicin	Frankia sp. EAN1pec
BGC0001987.1	0.43	Polyketide	koreenceine A, koreenceine B, koreenceine C, koreenceine D	Pseudomonas koreensis
BGC0001882.1	0.43	Polyketide	chrysoxanthone A, chrysoxanthone B, chrysoxanthone C	Penicillium rubens Wisconsin 54-1255
BGC0000899.1	0.43	Other	desosamine	Streptomyces narbonensis
BGC0001156.1	0.43	Terpene	platencin	Streptomyces platensis
BGC0001783.1	0.43	Other	streptonigrin	Streptomyces flocculus

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NC_017554.1 - Region 2 - redox-cofactor

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Location: 2,430,510 - 2,452,675 nt. (total: 22,166 nt) Show pHMM detection rules used

redox-cofactor: (cds(PF04055 and (TIGR04085 or SPASM)) and (TIGR02111 or TIGR03966) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001440.1	0.19	Other	cystargolide A, cystargolide B	Kitasatospora cystarginea
BGC0001441.1	0.18	Other	belactosin A, belactosin C	Streptomyces sp.
BGC0001562.1	0.14	NRP	curacomycin	Streptomyces curacoi
BGC0000906.1	0.13	Other	heme D1	Heliophilum fasciatum
BGC0001365.1	0.11	NRP	clapurines	Claviceps purpurea 20.1
BGC0001371.1	0.11	NRP	echinocandin B	Aspergillus nidulans NRRL 8112
BGC0000813.1	0.11	Alkaloid	K-252a	Nonomuraea longicatena
BGC0001569.1	0.10	NRP	dechlorocuracomycin	Streptomyces noursei ATCC 11455
BGC0001100.1	0.09	NRP, Polyketide	lankacidin C	Streptomyces rochei
BGC0001035.1	0.09	Other (Aminocoumarin), Polyketide, NRP	pneumocandin B0, pneumocandin A0	Glarea lozoyensis ATCC 20868

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001440.1	0.52	Other	cystargolide A, cystargolide B	Kitasatospora cystarginea
BGC0001441.1	0.50	Other	belactosin A, belactosin C	Streptomyces sp.
BGC0001562.1	0.43	NRP	curacomycin	Streptomyces curacoi
BGC0000906.1	0.42	Other	heme D1	Heliophilum fasciatum
BGC0001365.1	0.37	NRP	clapurines	Claviceps purpurea 20.1
BGC0001371.1	0.37	NRP	echinocandin B	Aspergillus nidulans NRRL 8112
BGC0000813.1	0.37	Alkaloid	K-252a	Nonomuraea longicatena
BGC0001569.1	0.35	NRP	dechlorocuracomycin	Streptomyces noursei ATCC 11455
BGC0001100.1	0.34	NRP, Polyketide	lankacidin C	Streptomyces rochei
BGC0001035.1	0.32	Other (Aminocoumarin), Polyketide, NRP	pneumocandin B0, pneumocandin A0	Glarea lozoyensis ATCC 20868

Similar known gene clusters

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NC_017554.1 - Region 3 - hserlactone

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Location: 2,937,749 - 2,958,360 nt. (total: 20,612 nt) Show pHMM detection rules used

hserlactone: Autoind_synth

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000896.1	0.17	Other	cycloserine	Streptomyces lavendulae subsp. lavendulae
BGC0000528.1	0.16	RiPP	michiganin A	Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0000016.1	0.15	Other	amphotericin B	Streptomyces nodosus
BGC0001120.1	0.15	NRP, Polyketide	burkholderic acid	Burkholderia thailandensis E264
BGC0001674.1	0.09	RiPP	MS-271	Streptomyces mirabilis
BGC0001921.1	0.09	Other	MS-271	Streptomyces sp.
BGC0002015.1	0.09	RiPP	aborycin	Streptomyces sp. ZS0098
BGC0001650.1	0.09	NRP	Le-pyrrolopyrazines	Lysobacter enzymogenes
BGC0000926.1	0.09	Other	rhizocticin A	Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0001302.1	0.09	Other	lomofungin	Streptomyces lomondensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000896.1	0.49	Other	cycloserine	Streptomyces lavendulae subsp. lavendulae
BGC0000528.1	0.47	RiPP	michiganin A	Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0000016.1	0.45	Other	amphotericin B	Streptomyces nodosus
BGC0001120.1	0.45	NRP, Polyketide	burkholderic acid	Burkholderia thailandensis E264
BGC0001674.1	0.34	RiPP	MS-271	Streptomyces mirabilis
BGC0001921.1	0.34	Other	MS-271	Streptomyces sp.
BGC0002015.1	0.34	RiPP	aborycin	Streptomyces sp. ZS0098
BGC0001650.1	0.34	NRP	Le-pyrrolopyrazines	Lysobacter enzymogenes
BGC0000926.1	0.34	Other	rhizocticin A	Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0001302.1	0.33	Other	lomofungin	Streptomyces lomondensis

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NC_017554.1 - Region 4 - thiopeptide

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Location: 3,017,908 - 3,044,173 nt. (total: 26,266 nt) Show pHMM detection rules used

thiopeptide: ((YcaO or TIGR03882) and ((thio_amide and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N or PF07366 or PF06968 or PF04055) or thiostrepton)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Thiopeptides

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000784.1	0.24	Saccharide	O-antigen	Pseudomonas aeruginosa
BGC0000781.1	0.16	Saccharide	O-antigen	Pseudomonas aeruginosa
BGC0001285.1	0.07	Other (Fatty acid)	pseudopyronine A, pseudopyronine B	Pseudomonas putida
BGC0000981.1	0.06	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E6
BGC0001302.1	0.06	Other	lomofungin	Streptomyces lomondensis
BGC0002012.1	0.05	Polyketide	julichrome Q3-3, julichrome Q3-5	Streptomyces afghaniensis 772
BGC0001283.1	0.05	Polyketide	arsono-polyketide	Streptomyces lividans 1326
BGC0000957.1	0.04	NRP, Polyketide	mycotrienin I	Streptomyces sp. XZQH13
BGC0000123.1	0.03	Polyketide	phoslactomycin B	Streptomyces sp. HK803

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000784.1	0.58	Saccharide	O-antigen	Pseudomonas aeruginosa
BGC0000781.1	0.47	Saccharide	O-antigen	Pseudomonas aeruginosa
BGC0001285.1	0.29	Other (Fatty acid)	pseudopyronine A, pseudopyronine B	Pseudomonas putida
BGC0000981.1	0.24	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E6
BGC0001302.1	0.24	Other	lomofungin	Streptomyces lomondensis
BGC0002012.1	0.23	Polyketide	julichrome Q3-3, julichrome Q3-5	Streptomyces afghaniensis 772
BGC0001283.1	0.22	Polyketide	arsono-polyketide	Streptomyces lividans 1326
BGC0000957.1	0.19	NRP, Polyketide	mycotrienin I	Streptomyces sp. XZQH13
BGC0000123.1	0.15	Polyketide	phoslactomycin B	Streptomyces sp. HK803

Similar known gene clusters

Thiopeptide predictions

No core peptides found.

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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Thiopeptides

Core peptide predictions

No core peptides found.

NC_017554.1 - Region 5 - siderophore

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Location: 3,857,506 - 3,868,860 nt. (total: 11,355 nt) Show pHMM detection rules used

siderophore: IucA_IucC

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001572.1	0.62	Other	desferrioxamine E	Pantoea agglomerans
BGC0001478.1	0.30	Other	desferrioxamine E	Streptomyces sp. ID38640
BGC0000941.1	0.28	Other	desferrioxamin B	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001453.1	0.27	Other	desferrioxamine	Streptomyces argillaceus
BGC0000940.1	0.27	Other	desferrioxamin B, desferrioxamine E	Streptomyces coelicolor A3(2)
BGC0000295.1	0.22	NRP	acinetoferrin	Acinetobacter haemolyticus
BGC0001713.1	0.21	Other	ochrobactin	Ochrobactrum anthropi
BGC0000939.1	0.19	Other	aerobactin	Grimontia hollisae
BGC0001499.1	0.19	Other	aerobactin	Pantoea ananatis
BGC0001498.1	0.19	Other	aerobactin	Xenorhabdus szentirmaii DSM 16338

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001572.1	0.85	Other	desferrioxamine E	Pantoea agglomerans
BGC0001478.1	0.64	Other	desferrioxamine E	Streptomyces sp. ID38640
BGC0000941.1	0.61	Other	desferrioxamin B	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001453.1	0.60	Other	desferrioxamine	Streptomyces argillaceus
BGC0000940.1	0.60	Other	desferrioxamin B, desferrioxamine E	Streptomyces coelicolor A3(2)
BGC0000295.1	0.55	NRP	acinetoferrin	Acinetobacter haemolyticus
BGC0001713.1	0.54	Other	ochrobactin	Ochrobactrum anthropi
BGC0000939.1	0.52	Other	aerobactin	Grimontia hollisae
BGC0001499.1	0.51	Other	aerobactin	Pantoea ananatis
BGC0001498.1	0.51	Other	aerobactin	Xenorhabdus szentirmaii DSM 16338

Similar known gene clusters

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NC_017554.1 - Region 6 - butyrolactone,phosphonate

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Location: 4,129,395 - 4,170,321 nt. (total: 40,927 nt) Show pHMM detection rules used

phosphonate: phosphonates
butyrolactone: AfsA

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000846.1	0.46	Other	tabtoxin	Pseudomonas syringae
BGC0000904.1	0.46	Other	FR-900098	Streptomyces rubellomurinus
BGC0001859.1	0.46	Other (Phosphonate)	fosfomycin	Pseudomonas syringae
BGC0000885.1	0.43	Other	4-hydroxy-3-nitrosobenzamide	Streptomyces murayamaensis
BGC0000937.1	0.36	Other	fosfazinomycin A	Streptomyces sp. WM6372
BGC0000897.1	0.36	Other	dehydrophos	Streptomyces luridus
BGC0001374.1	0.34	Other	thienodolin	Streptomyces albogriseolus
BGC0001411.1	0.31	Saccharide	polysaccharide B	Bacteroides fragilis
BGC0001739.1	0.30	Other	phosphonoacetic Acid	Streptomyces sp. NRRL F-525
BGC0000254.1	0.28	Polyketide	oxytetracycline	Streptomyces rimosus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000846.1	0.56	Other	tabtoxin	Pseudomonas syringae
BGC0000904.1	0.56	Other	FR-900098	Streptomyces rubellomurinus
BGC0001859.1	0.56	Other (Phosphonate)	fosfomycin	Pseudomonas syringae
BGC0000885.1	0.55	Other	4-hydroxy-3-nitrosobenzamide	Streptomyces murayamaensis
BGC0000897.1	0.51	Other	dehydrophos	Streptomyces luridus
BGC0000937.1	0.50	Other	fosfazinomycin A	Streptomyces sp. WM6372
BGC0001374.1	0.48	Other	thienodolin	Streptomyces albogriseolus
BGC0001411.1	0.46	Saccharide	polysaccharide B	Bacteroides fragilis
BGC0001739.1	0.46	Other	phosphonoacetic Acid	Streptomyces sp. NRRL F-525
BGC0000254.1	0.44	Polyketide	oxytetracycline	Streptomyces rimosus

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NC_017554.1 - Region 7 - siderophore

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Location: 4,256,841 - 4,271,246 nt. (total: 14,406 nt) Show pHMM detection rules used

siderophore: IucA_IucC

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001499.1	0.95	Other	aerobactin	Pantoea ananatis
BGC0001498.1	0.39	Other	aerobactin	Xenorhabdus szentirmaii DSM 16338
BGC0001572.1	0.29	Other	desferrioxamine E	Pantoea agglomerans
BGC0001555.1	0.27	RiPP	colicin V	Escherichia coli chi7122
BGC0000939.1	0.26	Other	aerobactin	Grimontia hollisae
BGC0001713.1	0.24	Other	ochrobactin	Ochrobactrum anthropi
BGC0000941.1	0.21	Other	desferrioxamin B	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001531.1	0.21	Other	bisucaberin B	Tenacibaculum mesophilum
BGC0000295.1	0.19	NRP	acinetoferrin	Acinetobacter haemolyticus
BGC0001453.1	0.17	Other	desferrioxamine	Streptomyces argillaceus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001499.1	0.99	Other	aerobactin	Pantoea ananatis
BGC0001498.1	0.71	Other	aerobactin	Xenorhabdus szentirmaii DSM 16338
BGC0001572.1	0.63	Other	desferrioxamine E	Pantoea agglomerans
BGC0001555.1	0.60	RiPP	colicin V	Escherichia coli chi7122
BGC0000939.1	0.59	Other	aerobactin	Grimontia hollisae
BGC0001713.1	0.58	Other	ochrobactin	Ochrobactrum anthropi
BGC0000941.1	0.54	Other	desferrioxamin B	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001531.1	0.54	Other	bisucaberin B	Tenacibaculum mesophilum
BGC0000295.1	0.52	NRP	acinetoferrin	Acinetobacter haemolyticus
BGC0001453.1	0.48	Other	desferrioxamine	Streptomyces argillaceus

Similar known gene clusters

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NC_017553.1 - Region 1 - terpene

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Location: 248,680 - 272,244 nt. (total: 23,565 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000638.1	0.90	Terpene	carotenoid	Pantoea ananatis
BGC0000641.1	0.57	Terpene	carotenoid	Enterobacteriaceae bacterium DC416
BGC0000656.1	0.53	Terpene	zeaxanthin	Xanthobacter autotrophicus Py2
BGC0000639.1	0.48	Terpene	carotenoid	Enterobacteriaceae bacterium DC260
BGC0000647.1	0.48	Terpene	carotenoid	Rhodobacter sphaeroides
BGC0000642.1	0.45	Terpene	carotenoid	Enterobacteriaceae bacterium DC413
BGC0000640.1	0.42	Terpene	carotenoid	Enterobacteriaceae bacterium DC404
BGC0000630.1	0.35	Terpene	(2R,3S,3'S)-2-hydroxyastaxanthin	Paracoccus haeundaensis
BGC0000635.1	0.27	Terpene	carotenoid	Paracoccus sp. N81106
BGC0000664.1	0.26	Terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000638.1	0.97	Terpene	carotenoid	Pantoea ananatis
BGC0000641.1	0.82	Terpene	carotenoid	Enterobacteriaceae bacterium DC416
BGC0000656.1	0.80	Terpene	zeaxanthin	Xanthobacter autotrophicus Py2
BGC0000639.1	0.77	Terpene	carotenoid	Enterobacteriaceae bacterium DC260
BGC0000647.1	0.77	Terpene	carotenoid	Rhodobacter sphaeroides
BGC0000642.1	0.75	Terpene	carotenoid	Enterobacteriaceae bacterium DC413
BGC0000640.1	0.73	Terpene	carotenoid	Enterobacteriaceae bacterium DC404
BGC0000630.1	0.68	Terpene	(2R,3S,3'S)-2-hydroxyastaxanthin	Paracoccus haeundaensis
BGC0000635.1	0.60	Terpene	carotenoid	Paracoccus sp. N81106
BGC0000664.1	0.60	Terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350

Similar known gene clusters

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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