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Overview
1.1
1.2
1.3
1.4
1.5
1.6
1.7
2.1

### Identified secondary metabolite regions using strictness 'relaxed'

NC_017554.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | hserlactone | 2,323,536 | 2,342,702 |
Region 1.2 | redox-cofactor | 2,430,510 | 2,452,675 | lankacidin C | NRP + Polyketide | 13%
Region 1.3 | hserlactone | 2,937,749 | 2,958,360 |
Region 1.4 | thiopeptide | 3,017,908 | 3,044,173 | O-antigen | Saccharide | 14%
Region 1.5 | siderophore | 3,857,506 | 3,868,860 | desferrioxamine E | Other | 100%
Region 1.6 | phosphonate,butyrolactone | 4,129,395 | 4,170,321 |
Region 1.7 | siderophore | 4,256,841 | 4,271,246 | aerobactin | Other | 77%

NC_017553.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 2.1 | terpene | 248,680 | 272,244 | carotenoid | Terpene | 100%

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | hserlactone | 2,323,536 | 2,342,702 |
Region 1.2 | redox-cofactor | 2,430,510 | 2,452,675 | lankacidin C | NRP + Polyketide | 13%
Region 1.3 | hserlactone | 2,937,749 | 2,958,360 |
Region 1.4 | thiopeptide | 3,017,908 | 3,044,173 | O-antigen | Saccharide | 14%
Region 1.5 | siderophore | 3,857,506 | 3,868,860 | desferrioxamine E | Other | 100%
Region 1.6 | phosphonate,butyrolactone | 4,129,395 | 4,170,321 |
Region 1.7 | siderophore | 4,256,841 | 4,271,246 | aerobactin | Other | 77%
Region 2.1 | terpene | 248,680 | 272,244 | carotenoid | Terpene | 100%

Compact view
NC_017554.1 - Region 1 - hserlactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,323,536 - 2,342,702 nt. (total: 19,167 nt) Show pHMM detection rules used
hserlactone: Autoind_synth

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | hserlactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001184.1 |  | 0.15 | Other | bacilysin | Bacillus velezensis FZB42
BGC0000243.1 |  | 0.15 | Polyketide | macrotetrolide | Streptomyces griseus subsp. griseus
BGC0001928.1 |  | 0.14 | Other | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37
BGC0001605.1 |  | 0.14 | Terpene | gibberellin | Sinorhizobium fredii NGR234
BGC0001197.1 |  | 0.14 | Polyketide | frankiamicin | Frankia sp. EAN1pec
BGC0001987.1 |  | 0.14 | Polyketide | koreenceine A, koreenceine B, koreenceine C, koreenceine D | Pseudomonas koreensis
BGC0001882.1 |  | 0.14 | Polyketide | chrysoxanthone A, chrysoxanthone B, chrysoxanthone C | Penicillium rubens Wisconsin 54-1255
BGC0000899.1 |  | 0.14 | Other | desosamine | Streptomyces narbonensis
BGC0001156.1 |  | 0.14 | Terpene | platencin | Streptomyces platensis
BGC0001783.1 |  | 0.14 | Other | streptonigrin | Streptomyces flocculus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001184.1 |  | 0.45 | Other | bacilysin | Bacillus velezensis FZB42
BGC0000243.1 |  | 0.44 | Polyketide | macrotetrolide | Streptomyces griseus subsp. griseus
BGC0001928.1 |  | 0.44 | Other | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37
BGC0001605.1 |  | 0.44 | Terpene | gibberellin | Sinorhizobium fredii NGR234
BGC0001197.1 |  | 0.44 | Polyketide | frankiamicin | Frankia sp. EAN1pec
BGC0001987.1 |  | 0.43 | Polyketide | koreenceine A, koreenceine B, koreenceine C, koreenceine D | Pseudomonas koreensis
BGC0001882.1 |  | 0.43 | Polyketide | chrysoxanthone A, chrysoxanthone B, chrysoxanthone C | Penicillium rubens Wisconsin 54-1255
BGC0000899.1 |  | 0.43 | Other | desosamine | Streptomyces narbonensis
BGC0001156.1 |  | 0.43 | Terpene | platencin | Streptomyces platensis
BGC0001783.1 |  | 0.43 | Other | streptonigrin | Streptomyces flocculus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NC_017554.1 - Region 2 - redox-cofactor
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,430,510 - 2,452,675 nt. (total: 22,166 nt) Show pHMM detection rules used
redox-cofactor: (cds(PF04055 and (TIGR04085 or SPASM)) and (TIGR02111 or TIGR03966) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | redox-cofactor | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001440.1 |  | 0.19 | Other | cystargolide A, cystargolide B | Kitasatospora cystarginea
BGC0001441.1 |  | 0.18 | Other | belactosin A, belactosin C | Streptomyces sp.
BGC0001562.1 |  | 0.14 | NRP | curacomycin | Streptomyces curacoi
BGC0000906.1 |  | 0.13 | Other | heme D1 | Heliophilum fasciatum
BGC0001365.1 |  | 0.11 | NRP | clapurines | Claviceps purpurea 20.1
BGC0001371.1 |  | 0.11 | NRP | echinocandin B | Aspergillus nidulans NRRL 8112
BGC0000813.1 |  | 0.11 | Alkaloid | K-252a | Nonomuraea longicatena
BGC0001569.1 |  | 0.10 | NRP | dechlorocuracomycin | Streptomyces noursei ATCC 11455
BGC0001100.1 |  | 0.09 | NRP, Polyketide | lankacidin C | Streptomyces rochei
BGC0001035.1 |  | 0.09 | Other (Aminocoumarin), Polyketide, NRP | pneumocandin B0, pneumocandin A0 | Glarea lozoyensis ATCC 20868

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001440.1 |  | 0.52 | Other | cystargolide A, cystargolide B | Kitasatospora cystarginea
BGC0001441.1 |  | 0.50 | Other | belactosin A, belactosin C | Streptomyces sp.
BGC0001562.1 |  | 0.43 | NRP | curacomycin | Streptomyces curacoi
BGC0000906.1 |  | 0.42 | Other | heme D1 | Heliophilum fasciatum
BGC0001365.1 |  | 0.37 | NRP | clapurines | Claviceps purpurea 20.1
BGC0001371.1 |  | 0.37 | NRP | echinocandin B | Aspergillus nidulans NRRL 8112
BGC0000813.1 |  | 0.37 | Alkaloid | K-252a | Nonomuraea longicatena
BGC0001569.1 |  | 0.35 | NRP | dechlorocuracomycin | Streptomyces noursei ATCC 11455
BGC0001100.1 |  | 0.34 | NRP, Polyketide | lankacidin C | Streptomyces rochei
BGC0001035.1 |  | 0.32 | Other (Aminocoumarin), Polyketide, NRP | pneumocandin B0, pneumocandin A0 | Glarea lozoyensis ATCC 20868

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NC_017554.1 - Region 3 - hserlactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,937,749 - 2,958,360 nt. (total: 20,612 nt) Show pHMM detection rules used
hserlactone: Autoind_synth

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | hserlactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000896.1 |  | 0.17 | Other | cycloserine | Streptomyces lavendulae subsp. lavendulae
BGC0000528.1 |  | 0.16 | RiPP | michiganin A | Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0000016.1 |  | 0.15 | Other | amphotericin B | Streptomyces nodosus
BGC0001120.1 |  | 0.15 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0001674.1 |  | 0.09 | RiPP | MS-271 | Streptomyces mirabilis
BGC0001921.1 |  | 0.09 | Other | MS-271 | Streptomyces sp.
BGC0002015.1 |  | 0.09 | RiPP | aborycin | Streptomyces sp. ZS0098
BGC0001650.1 |  | 0.09 | NRP | Le-pyrrolopyrazines | Lysobacter enzymogenes
BGC0000926.1 |  | 0.09 | Other | rhizocticin A | Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0001302.1 |  | 0.09 | Other | lomofungin | Streptomyces lomondensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000896.1 |  | 0.49 | Other | cycloserine | Streptomyces lavendulae subsp. lavendulae
BGC0000528.1 |  | 0.47 | RiPP | michiganin A | Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0000016.1 |  | 0.45 | Other | amphotericin B | Streptomyces nodosus
BGC0001120.1 |  | 0.45 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0001674.1 |  | 0.34 | RiPP | MS-271 | Streptomyces mirabilis
BGC0001921.1 |  | 0.34 | Other | MS-271 | Streptomyces sp.
BGC0002015.1 |  | 0.34 | RiPP | aborycin | Streptomyces sp. ZS0098
BGC0001650.1 |  | 0.34 | NRP | Le-pyrrolopyrazines | Lysobacter enzymogenes
BGC0000926.1 |  | 0.34 | Other | rhizocticin A | Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0001302.1 |  | 0.33 | Other | lomofungin | Streptomyces lomondensis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NC_017554.1 - Region 4 - thiopeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,017,908 - 3,044,173 nt. (total: 26,266 nt) Show pHMM detection rules used
thiopeptide: ((YcaO or TIGR03882) and ((thio_amide and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N or PF07366 or PF06968 or PF04055) or thiostrepton)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Thiopeptides
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | thiopeptide | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000784.1 |  | 0.24 | Saccharide | O-antigen | Pseudomonas aeruginosa
BGC0000781.1 |  | 0.16 | Saccharide | O-antigen | Pseudomonas aeruginosa
BGC0001285.1 |  | 0.07 | Other (Fatty acid) | pseudopyronine A, pseudopyronine B | Pseudomonas putida
BGC0000981.1 |  | 0.06 | NRP, Polyketide | cylindrospermopsin | Aphanizomenon sp. 10E6
BGC0001302.1 |  | 0.06 | Other | lomofungin | Streptomyces lomondensis
BGC0002012.1 |  | 0.05 | Polyketide | julichrome Q3-3, julichrome Q3-5 | Streptomyces afghaniensis 772
BGC0001283.1 |  | 0.05 | Polyketide | arsono-polyketide | Streptomyces lividans 1326
BGC0000957.1 |  | 0.04 | NRP, Polyketide | mycotrienin I | Streptomyces sp. XZQH13
BGC0000123.1 |  | 0.03 | Polyketide | phoslactomycin B | Streptomyces sp. HK803

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000784.1 |  | 0.58 | Saccharide | O-antigen | Pseudomonas aeruginosa
BGC0000781.1 |  | 0.47 | Saccharide | O-antigen | Pseudomonas aeruginosa
BGC0001285.1 |  | 0.29 | Other (Fatty acid) | pseudopyronine A, pseudopyronine B | Pseudomonas putida
BGC0000981.1 |  | 0.24 | NRP, Polyketide | cylindrospermopsin | Aphanizomenon sp. 10E6
BGC0001302.1 |  | 0.24 | Other | lomofungin | Streptomyces lomondensis
BGC0002012.1 |  | 0.23 | Polyketide | julichrome Q3-3, julichrome Q3-5 | Streptomyces afghaniensis 772
BGC0001283.1 |  | 0.22 | Polyketide | arsono-polyketide | Streptomyces lividans 1326
BGC0000957.1 |  | 0.19 | NRP, Polyketide | mycotrienin I | Streptomyces sp. XZQH13
BGC0000123.1 |  | 0.15 | Polyketide | phoslactomycin B | Streptomyces sp. HK803

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Thiopeptide predictions
Lists the possible core peptides for each biosynthetic enzyme, including the predicted class. Each core peptide shows the leader and core peptide sequences, separated by a dash. Predicted tail sequences are also shown.
No core peptides found.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
Thiopeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists its possible molecular weights and the scores for cleavage site prediction and RODEO. If relevant, other features, such as macrocycle and amidation, will also be listed.
No core peptides found.
NC_017554.1 - Region 5 - siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,857,506 - 3,868,860 nt. (total: 11,355 nt) Show pHMM detection rules used
siderophore: IucA_IucC

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | siderophore | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001572.1 |  | 0.62 | Other | desferrioxamine E | Pantoea agglomerans
BGC0001478.1 |  | 0.30 | Other | desferrioxamine E | Streptomyces sp. ID38640
BGC0000941.1 |  | 0.28 | Other | desferrioxamin B | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001453.1 |  | 0.27 | Other | desferrioxamine | Streptomyces argillaceus
BGC0000940.1 |  | 0.27 | Other | desferrioxamin B, desferrioxamine E | Streptomyces coelicolor A3(2)
BGC0000295.1 |  | 0.22 | NRP | acinetoferrin | Acinetobacter haemolyticus
BGC0001713.1 |  | 0.21 | Other | ochrobactin | Ochrobactrum anthropi
BGC0000939.1 |  | 0.19 | Other | aerobactin | Grimontia hollisae
BGC0001499.1 |  | 0.19 | Other | aerobactin | Pantoea ananatis
BGC0001498.1 |  | 0.19 | Other | aerobactin | Xenorhabdus szentirmaii DSM 16338

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001572.1 |  | 0.85 | Other | desferrioxamine E | Pantoea agglomerans
BGC0001478.1 |  | 0.64 | Other | desferrioxamine E | Streptomyces sp. ID38640
BGC0000941.1 |  | 0.61 | Other | desferrioxamin B | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001453.1 |  | 0.60 | Other | desferrioxamine | Streptomyces argillaceus
BGC0000940.1 |  | 0.60 | Other | desferrioxamin B, desferrioxamine E | Streptomyces coelicolor A3(2)
BGC0000295.1 |  | 0.55 | NRP | acinetoferrin | Acinetobacter haemolyticus
BGC0001713.1 |  | 0.54 | Other | ochrobactin | Ochrobactrum anthropi
BGC0000939.1 |  | 0.52 | Other | aerobactin | Grimontia hollisae
BGC0001499.1 |  | 0.51 | Other | aerobactin | Pantoea ananatis
BGC0001498.1 |  | 0.51 | Other | aerobactin | Xenorhabdus szentirmaii DSM 16338

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NC_017554.1 - Region 6 - butyrolactone,phosphonate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 4,129,395 - 4,170,321 nt. (total: 40,927 nt) Show pHMM detection rules used
phosphonate: phosphonates
butyrolactone: AfsA

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | phosphonate | butyrolactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0000846.1 |  |  | 0.46 | Other | tabtoxin | Pseudomonas syringae
BGC0000904.1 |  |  | 0.46 | Other | FR-900098 | Streptomyces rubellomurinus
BGC0001859.1 |  |  | 0.46 | Other (Phosphonate) | fosfomycin | Pseudomonas syringae
BGC0000885.1 |  |  | 0.43 | Other | 4-hydroxy-3-nitrosobenzamide | Streptomyces murayamaensis
BGC0000937.1 |  |  | 0.36 | Other | fosfazinomycin A | Streptomyces sp. WM6372
BGC0000897.1 |  |  | 0.36 | Other | dehydrophos | Streptomyces luridus
BGC0001374.1 |  |  | 0.34 | Other | thienodolin | Streptomyces albogriseolus
BGC0001411.1 |  |  | 0.31 | Saccharide | polysaccharide B | Bacteroides fragilis
BGC0001739.1 |  |  | 0.30 | Other | phosphonoacetic Acid | Streptomyces sp. NRRL F-525
BGC0000254.1 |  |  | 0.28 | Polyketide | oxytetracycline | Streptomyces rimosus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000846.1 |  | 0.56 | Other | tabtoxin | Pseudomonas syringae
BGC0000904.1 |  | 0.56 | Other | FR-900098 | Streptomyces rubellomurinus
BGC0001859.1 |  | 0.56 | Other (Phosphonate) | fosfomycin | Pseudomonas syringae
BGC0000885.1 |  | 0.55 | Other | 4-hydroxy-3-nitrosobenzamide | Streptomyces murayamaensis
BGC0000897.1 |  | 0.51 | Other | dehydrophos | Streptomyces luridus
BGC0000937.1 |  | 0.50 | Other | fosfazinomycin A | Streptomyces sp. WM6372
BGC0001374.1 |  | 0.48 | Other | thienodolin | Streptomyces albogriseolus
BGC0001411.1 |  | 0.46 | Saccharide | polysaccharide B | Bacteroides fragilis
BGC0001739.1 |  | 0.46 | Other | phosphonoacetic Acid | Streptomyces sp. NRRL F-525
BGC0000254.1 |  | 0.44 | Polyketide | oxytetracycline | Streptomyces rimosus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NC_017554.1 - Region 7 - siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 4,256,841 - 4,271,246 nt. (total: 14,406 nt) Show pHMM detection rules used
siderophore: IucA_IucC

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | siderophore | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001499.1 |  | 0.95 | Other | aerobactin | Pantoea ananatis
BGC0001498.1 |  | 0.39 | Other | aerobactin | Xenorhabdus szentirmaii DSM 16338
BGC0001572.1 |  | 0.29 | Other | desferrioxamine E | Pantoea agglomerans
BGC0001555.1 |  | 0.27 | RiPP | colicin V | Escherichia coli chi7122
BGC0000939.1 |  | 0.26 | Other | aerobactin | Grimontia hollisae
BGC0001713.1 |  | 0.24 | Other | ochrobactin | Ochrobactrum anthropi
BGC0000941.1 |  | 0.21 | Other | desferrioxamin B | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001531.1 |  | 0.21 | Other | bisucaberin B | Tenacibaculum mesophilum
BGC0000295.1 |  | 0.19 | NRP | acinetoferrin | Acinetobacter haemolyticus
BGC0001453.1 |  | 0.17 | Other | desferrioxamine | Streptomyces argillaceus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001499.1 |  | 0.99 | Other | aerobactin | Pantoea ananatis
BGC0001498.1 |  | 0.71 | Other | aerobactin | Xenorhabdus szentirmaii DSM 16338
BGC0001572.1 |  | 0.63 | Other | desferrioxamine E | Pantoea agglomerans
BGC0001555.1 |  | 0.60 | RiPP | colicin V | Escherichia coli chi7122
BGC0000939.1 |  | 0.59 | Other | aerobactin | Grimontia hollisae
BGC0001713.1 |  | 0.58 | Other | ochrobactin | Ochrobactrum anthropi
BGC0000941.1 |  | 0.54 | Other | desferrioxamin B | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001531.1 |  | 0.54 | Other | bisucaberin B | Tenacibaculum mesophilum
BGC0000295.1 |  | 0.52 | NRP | acinetoferrin | Acinetobacter haemolyticus
BGC0001453.1 |  | 0.48 | Other | desferrioxamine | Streptomyces argillaceus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NC_017553.1 - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 248,680 - 272,244 nt. (total: 23,565 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000638.1 |  | 0.90 | Terpene | carotenoid | Pantoea ananatis
BGC0000641.1 |  | 0.57 | Terpene | carotenoid | Enterobacteriaceae bacterium DC416
BGC0000656.1 |  | 0.53 | Terpene | zeaxanthin | Xanthobacter autotrophicus Py2
BGC0000639.1 |  | 0.48 | Terpene | carotenoid | Enterobacteriaceae bacterium DC260
BGC0000647.1 |  | 0.48 | Terpene | carotenoid | Rhodobacter sphaeroides
BGC0000642.1 |  | 0.45 | Terpene | carotenoid | Enterobacteriaceae bacterium DC413
BGC0000640.1 |  | 0.42 | Terpene | carotenoid | Enterobacteriaceae bacterium DC404
BGC0000630.1 |  | 0.35 | Terpene | (2R,3S,3'S)-2-hydroxyastaxanthin | Paracoccus haeundaensis
BGC0000635.1 |  | 0.27 | Terpene | carotenoid | Paracoccus sp. N81106
BGC0000664.1 |  | 0.26 | Terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000638.1 |  | 0.97 | Terpene | carotenoid | Pantoea ananatis
BGC0000641.1 |  | 0.82 | Terpene | carotenoid | Enterobacteriaceae bacterium DC416
BGC0000656.1 |  | 0.80 | Terpene | zeaxanthin | Xanthobacter autotrophicus Py2
BGC0000639.1 |  | 0.77 | Terpene | carotenoid | Enterobacteriaceae bacterium DC260
BGC0000647.1 |  | 0.77 | Terpene | carotenoid | Rhodobacter sphaeroides
BGC0000642.1 |  | 0.75 | Terpene | carotenoid | Enterobacteriaceae bacterium DC413
BGC0000640.1 |  | 0.73 | Terpene | carotenoid | Enterobacteriaceae bacterium DC404
BGC0000630.1 |  | 0.68 | Terpene | (2R,3S,3'S)-2-hydroxyastaxanthin | Paracoccus haeundaensis
BGC0000635.1 |  | 0.60 | Terpene | carotenoid | Paracoccus sp. N81106
BGC0000664.1 |  | 0.60 | Terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names