GCF_008107585.1_ASM810758v1_genomic - 5 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_VSLA01000001 (original name was: NZ_VSLA01000001.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	lassopeptide	1	4,490

NZ_VSLA01000002 (original name was: NZ_VSLA01000002.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 12.1	NRPS-like	210,795	252,654

NZ_VSLA01000024 (original name was: NZ_VSLA01000024.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 16.1	NRPS	270,103	316,816

NZ_VSLA01000030 (original name was: NZ_VSLA01000030.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 23.1	ranthipeptide	98,063	119,412

NZ_VSLA01000004 (original name was: NZ_VSLA01000004.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 25.1	terpene	70,183	91,043

Region	Type	From	To	Similarity
Region 1.1	lassopeptide	1	4,490
Region 12.1	NRPS-like	210,795	252,654
Region 16.1	NRPS	270,103	316,816
Region 23.1	ranthipeptide	98,063	119,412
Region 25.1	terpene	70,183	91,043

No secondary metabolite regions were found in these records:: NZ_VSLA01000011 (original name was: NZ_VSLA01000011.1); NZ_VSLA01000012 (original name was: NZ_VSLA01000012.1); NZ_VSLA01000013 (original name was: NZ_VSLA01000013.1); NZ_VSLA01000014 (original name was: NZ_VSLA01000014.1); NZ_VSLA01000015 (original name was: NZ_VSLA01000015.1); NZ_VSLA01000016 (original name was: NZ_VSLA01000016.1); NZ_VSLA01000017 (original name was: NZ_VSLA01000017.1); NZ_VSLA01000018 (original name was: NZ_VSLA01000018.1); NZ_VSLA01000019 (original name was: NZ_VSLA01000019.1); NZ_VSLA01000020 (original name was: NZ_VSLA01000020.1); NZ_VSLA01000021 (original name was: NZ_VSLA01000021.1); NZ_VSLA01000022 (original name was: NZ_VSLA01000022.1); NZ_VSLA01000023 (original name was: NZ_VSLA01000023.1); NZ_VSLA01000025 (original name was: NZ_VSLA01000025.1); NZ_VSLA01000026 (original name was: NZ_VSLA01000026.1); NZ_VSLA01000027 (original name was: NZ_VSLA01000027.1); NZ_VSLA01000028 (original name was: NZ_VSLA01000028.1); NZ_VSLA01000029 (original name was: NZ_VSLA01000029.1); NZ_VSLA01000003 (original name was: NZ_VSLA01000003.1); NZ_VSLA01000031 (original name was: NZ_VSLA01000031.1); NZ_VSLA01000005 (original name was: NZ_VSLA01000005.1); NZ_VSLA01000006 (original name was: NZ_VSLA01000006.1); NZ_VSLA01000007 (original name was: NZ_VSLA01000007.1); NZ_VSLA01000009 (original name was: NZ_VSLA01000009.1); NZ_VSLA01000008 (original name was: NZ_VSLA01000008.1); NZ_VSLA01000010 (original name was: NZ_VSLA01000010.1)

Compact view

c00001_NZ_VSLA.. - Region 1 - lassopeptide

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Location: 1 - 4,490 nt. (total: 4,490 nt) Show pHMM detection rules used

Region on contig edge.

lassopeptide: (PF13471 and Asn_synthase or micJ25 or mcjC)

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Gene details

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MIBiG comparison

KnownClusterBlast

Lasso peptides

Similar gene clusters

Analysis type:

No matches found.

Similar known gene clusters

No matches found.

Lasso peptide predictions

Lassopeptides - No core peptides found.

Lasso peptides

Core peptide predictions

No core peptides found.

c00012_NZ_VSLA.. - Region 1 - NRPS-like

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Location: 210,795 - 252,654 nt. (total: 41,860 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Gene details

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NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001343.1	0.24	Polyketide	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0001831.1	0.23	Polyketide	alkylpyrone-407, alkylpyrone-393	Myxococcus xanthus DK 1622
BGC0001723.1	0.23	Polyketide	oviedomycin	Streptomyces antibioticus
BGC0001591.1	0.22	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.22	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0000886.1	0.22	Other	allylmalonyl-CoA	Streptomyces tsukubensis
BGC0000220.1	0.22	Polyketide	enterocin	Streptomyces maritimus
BGC0001895.1	0.21	Polyketide	huanglongmycin A, huanglongmycin B, huanglongmycin C	Streptomyces sp. CB09001
BGC0001940.1	0.21	Polyketide	pyxidicycline A, pyxidicycline B	Pyxidicoccus fallax
BGC0000231.1	0.21	Polyketide	griseusin	Streptomyces griseus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001343.1	0.57	Polyketide	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0001831.1	0.56	Polyketide	alkylpyrone-407, alkylpyrone-393	Myxococcus xanthus DK 1622
BGC0001723.1	0.56	Polyketide	oviedomycin	Streptomyces antibioticus
BGC0001591.1	0.55	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.55	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0000886.1	0.55	Other	allylmalonyl-CoA	Streptomyces tsukubensis
BGC0000220.1	0.55	Polyketide	enterocin	Streptomyces maritimus
BGC0001895.1	0.54	Polyketide	huanglongmycin A, huanglongmycin B, huanglongmycin C	Streptomyces sp. CB09001
BGC0001940.1	0.54	Polyketide	pyxidicycline A, pyxidicycline B	Pyxidicoccus fallax
BGC0000231.1	0.54	Polyketide	griseusin	Streptomyces griseus

Similar known gene clusters

No matches found.

Module view

Legend

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 210794 - 252654:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg12_192

Search NORINE for peptide: strict or relaxed

AMP-binding (73..341): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: fVpWvGfiFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 50% (weak)

ctg12_208

Search NORINE for peptide: strict or relaxed

AMP-binding (23..430): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: phe, trp
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: GfygfGAmGK
Nearest Stachelhaus code:: tcl
Stachelhaus code match:: 50% (weak)

c00016_NZ_VSLA.. - Region 1 - NRPS

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Location: 270,103 - 316,816 nt. (total: 46,714 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000308.1	0.26	NRP	aureusimine	Staphylococcus aureus subsp. aureus str. JKD6008
BGC0001575.1	0.25	NRP	dipeptide aldehydes	Ruminococcus sp. 5_1_39BFAA
BGC0001627.1	0.22	NRP	isonitrile lipopeptides	Mycobacterium tuberculosis H37Rv
BGC0001758.1	0.21	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001479.1	0.21	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001128.1	0.21	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001135.1	0.21	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001825.1	0.21	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001615.1	0.21	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0001833.1	0.21	NRP	icosalide A, icosalide B	Burkholderia gladioli

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000308.1	0.59	NRP	aureusimine	Staphylococcus aureus subsp. aureus str. JKD6008
BGC0001575.1	0.58	NRP	dipeptide aldehydes	Ruminococcus sp. 5_1_39BFAA
BGC0001627.1	0.55	NRP	isonitrile lipopeptides	Mycobacterium tuberculosis H37Rv
BGC0001758.1	0.54	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001479.1	0.53	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001128.1	0.53	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001135.1	0.53	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001825.1	0.53	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001615.1	0.53	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0001833.1	0.53	NRP	icosalide A, icosalide B	Burkholderia gladioli

Similar known gene clusters

No matches found.

Module view

Legend

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 270102 - 316816:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (leu - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg16_259

Search NORINE for peptide: strict or relaxed

AMP-binding (267..653): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DAmFsGLViK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 70% (weak)

AMP-binding (1262..1654): X

NRPSPredictor2: hydrophobic-aromatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DALiiGAVeK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 70% (weak)

c00023_NZ_VSLA.. - Region 1 - ranthipeptide

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Location: 98,063 - 119,412 nt. (total: 21,350 nt) Show pHMM detection rules used

ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001664.1	0.17	Terpene	merosterol	Scytonema sp. PCC 10023
BGC0000665.1	0.15	Terpene, Alkaloid	xiamycin	Streptomyces sp. HKI0576
BGC0001156.1	0.15	Terpene	platencin	Streptomyces platensis
BGC0000666.1	0.15	Terpene	xiamycin A	Streptomyces sp. SCSIO 02999
BGC0001140.1	0.15	Terpene	platensimycin, platencin	Streptomyces platensis
BGC0001605.1	0.15	Terpene	gibberellin	Sinorhizobium fredii NGR234
BGC0000906.1	0.14	Other	heme D1	Heliophilum fasciatum
BGC0000905.1	0.14	Other	heme D1	Heliobacillus mobilis
BGC0001914.1	0.13	Other	benzastatin J, 7-hydroxyl benzastatin B, 7-hydroxyl O-demethylbenzastatin A, JBIR-67, 7-hydroxyl benzastatin F, 7-hydroxyl O-demethylbenzastatin D, O-demethylvirantmycin, 7-hydroxyl benzastatin D, virantmycin, benzastatin K, methylbenzastatin K	Streptomyces sp. RI18
BGC0001529.1	0.13	Alkaloid	bezastatin derivates	Streptomyces sp. RI18

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001664.1	0.48	Terpene	merosterol	Scytonema sp. PCC 10023
BGC0000665.1	0.45	Terpene, Alkaloid	xiamycin	Streptomyces sp. HKI0576
BGC0001156.1	0.45	Terpene	platencin	Streptomyces platensis
BGC0000666.1	0.45	Terpene	xiamycin A	Streptomyces sp. SCSIO 02999
BGC0001140.1	0.45	Terpene	platensimycin, platencin	Streptomyces platensis
BGC0001605.1	0.44	Terpene	gibberellin	Sinorhizobium fredii NGR234
BGC0000906.1	0.44	Other	heme D1	Heliophilum fasciatum
BGC0000905.1	0.44	Other	heme D1	Heliobacillus mobilis
BGC0001914.1	0.41	Other	benzastatin J, 7-hydroxyl benzastatin B, 7-hydroxyl O-demethylbenzastatin A, JBIR-67, 7-hydroxyl benzastatin F, 7-hydroxyl O-demethylbenzastatin D, O-demethylvirantmycin, 7-hydroxyl benzastatin D, virantmycin, benzastatin K, methylbenzastatin K	Streptomyces sp. RI18
BGC0001529.1	0.41	Alkaloid	bezastatin derivates	Streptomyces sp. RI18

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

c00025_NZ_VSLA.. - Region 1 - terpene

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Location: 70,183 - 91,043 nt. (total: 20,861 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000647.1	0.45	Terpene	carotenoid	Rhodobacter sphaeroides
BGC0000650.1	0.27	Terpene	carotenoid	Algoriphagus sp. KK10202C
BGC0000637.1	0.23	Terpene	carotenoid	Corynebacterium glutamicum
BGC0000648.1	0.23	Terpene	carotenoid	Myxococcus xanthus
BGC0000646.1	0.21	Terpene	β-carotein	uncultured bacterium
BGC0001227.1	0.21	Terpene	isorenieratene	Streptomyces collinus Tu 365
BGC0000644.1	0.21	Terpene	carotenoid	Dietzia sp. CQ4
BGC0000640.1	0.21	Terpene	carotenoid	Enterobacteriaceae bacterium DC404
BGC0000664.1	0.20	Terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000633.1	0.20	Terpene	carotenoid	Streptomyces avermitilis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000647.1	0.76	Terpene	carotenoid	Rhodobacter sphaeroides
BGC0000650.1	0.60	Terpene	carotenoid	Algoriphagus sp. KK10202C
BGC0000637.1	0.56	Terpene	carotenoid	Corynebacterium glutamicum
BGC0000648.1	0.56	Terpene	carotenoid	Myxococcus xanthus
BGC0000646.1	0.54	Terpene	β-carotein	uncultured bacterium
BGC0001227.1	0.53	Terpene	isorenieratene	Streptomyces collinus Tu 365
BGC0000644.1	0.53	Terpene	carotenoid	Dietzia sp. CQ4
BGC0000640.1	0.53	Terpene	carotenoid	Enterobacteriaceae bacterium DC404
BGC0000664.1	0.53	Terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000633.1	0.53	Terpene	carotenoid	Streptomyces avermitilis

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names