Select genomic region:
Overview
1.1
12.1
16.1
23.1
25.1

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_VSLA01000001 (original name was: NZ_VSLA01000001.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | lassopeptide | 1 | 4,490 |

NZ_VSLA01000002 (original name was: NZ_VSLA01000002.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 12.1 | NRPS-like | 210,795 | 252,654 |

NZ_VSLA01000024 (original name was: NZ_VSLA01000024.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 16.1 | NRPS | 270,103 | 316,816 |

NZ_VSLA01000030 (original name was: NZ_VSLA01000030.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 23.1 | ranthipeptide | 98,063 | 119,412 |

NZ_VSLA01000004 (original name was: NZ_VSLA01000004.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 25.1 | terpene | 70,183 | 91,043 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | lassopeptide | 1 | 4,490 |
Region 12.1 | NRPS-like | 210,795 | 252,654 |
Region 16.1 | NRPS | 270,103 | 316,816 |
Region 23.1 | ranthipeptide | 98,063 | 119,412 |
Region 25.1 | terpene | 70,183 | 91,043 |

No secondary metabolite regions were found in these records:
  NZ_VSLA01000011 (original name was: NZ_VSLA01000011.1)
  NZ_VSLA01000012 (original name was: NZ_VSLA01000012.1)
  NZ_VSLA01000013 (original name was: NZ_VSLA01000013.1)
  NZ_VSLA01000014 (original name was: NZ_VSLA01000014.1)
  NZ_VSLA01000015 (original name was: NZ_VSLA01000015.1)
  NZ_VSLA01000016 (original name was: NZ_VSLA01000016.1)
  NZ_VSLA01000017 (original name was: NZ_VSLA01000017.1)
  NZ_VSLA01000018 (original name was: NZ_VSLA01000018.1)
  NZ_VSLA01000019 (original name was: NZ_VSLA01000019.1)
  NZ_VSLA01000020 (original name was: NZ_VSLA01000020.1)
  NZ_VSLA01000021 (original name was: NZ_VSLA01000021.1)
  NZ_VSLA01000022 (original name was: NZ_VSLA01000022.1)
  NZ_VSLA01000023 (original name was: NZ_VSLA01000023.1)
  NZ_VSLA01000025 (original name was: NZ_VSLA01000025.1)
  NZ_VSLA01000026 (original name was: NZ_VSLA01000026.1)
  NZ_VSLA01000027 (original name was: NZ_VSLA01000027.1)
  NZ_VSLA01000028 (original name was: NZ_VSLA01000028.1)
  NZ_VSLA01000029 (original name was: NZ_VSLA01000029.1)
  NZ_VSLA01000003 (original name was: NZ_VSLA01000003.1)
  NZ_VSLA01000031 (original name was: NZ_VSLA01000031.1)
  NZ_VSLA01000005 (original name was: NZ_VSLA01000005.1)
  NZ_VSLA01000006 (original name was: NZ_VSLA01000006.1)
  NZ_VSLA01000007 (original name was: NZ_VSLA01000007.1)
  NZ_VSLA01000009 (original name was: NZ_VSLA01000009.1)
  NZ_VSLA01000008 (original name was: NZ_VSLA01000008.1)
  NZ_VSLA01000010 (original name was: NZ_VSLA01000010.1)

Compact view
c00001_NZ_VSLA.. - Region 1 - lassopeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1 - 4,490 nt. (total: 4,490 nt) Show pHMM detection rules used
Region on contig edge.
lassopeptide: (PF13471 and Asn_synthase or micJ25 or mcjC)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Lasso peptides
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

No matches found.

No matches found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Lasso peptide predictions
Lists the possible core peptides for each biosynthetic enzyme, including the predicted class. Each core peptide shows the leader and core peptide sequences, separated by a dash.
Lassopeptides - No core peptides found.
Lasso peptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of disulfide bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.
No core peptides found.
c00012_NZ_VSLA.. - Region 1 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 210,795 - 252,654 nt. (total: 41,860 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001343.1 |  | 0.24 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15
BGC0001831.1 |  | 0.23 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0001723.1 |  | 0.23 | Polyketide | oviedomycin | Streptomyces antibioticus
BGC0001591.1 |  | 0.22 | Other | fatty acid enol ester | uncultured bacterium CSLC2
BGC0001688.1 |  | 0.22 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0000886.1 |  | 0.22 | Other | allylmalonyl-CoA | Streptomyces tsukubensis
BGC0000220.1 |  | 0.22 | Polyketide | enterocin | Streptomyces maritimus
BGC0001895.1 |  | 0.21 | Polyketide | huanglongmycin A, huanglongmycin B, huanglongmycin C | Streptomyces sp. CB09001
BGC0001940.1 |  | 0.21 | Polyketide | pyxidicycline A, pyxidicycline B | Pyxidicoccus fallax
BGC0000231.1 |  | 0.21 | Polyketide | griseusin | Streptomyces griseus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001343.1 |  | 0.57 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15
BGC0001831.1 |  | 0.56 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0001723.1 |  | 0.56 | Polyketide | oviedomycin | Streptomyces antibioticus
BGC0001591.1 |  | 0.55 | Other | fatty acid enol ester | uncultured bacterium CSLC2
BGC0001688.1 |  | 0.55 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0000886.1 |  | 0.55 | Other | allylmalonyl-CoA | Streptomyces tsukubensis
BGC0000220.1 |  | 0.55 | Polyketide | enterocin | Streptomyces maritimus
BGC0001895.1 |  | 0.54 | Polyketide | huanglongmycin A, huanglongmycin B, huanglongmycin C | Streptomyces sp. CB09001
BGC0001940.1 |  | 0.54 | Polyketide | pyxidicycline A, pyxidicycline B | Pyxidicoccus fallax
BGC0000231.1 |  | 0.54 | Polyketide | griseusin | Streptomyces griseus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 210794 - 252654:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (X)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg12_192: X
  Search NORINE for peptide: strict or relaxed
  AMP-binding (73..341): X
  NRPSPredictor2: (unknown)
  SVM prediction details:
    NOTE: outside applicability domain
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      gly, ala, val, leu, ile, abu, iva
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      fVpWvGfiFK
    Nearest Stachelhaus code:
      val
    Stachelhaus code match:
      50% (weak)
ctg12_208: X
  Search NORINE for peptide: strict or relaxed
  AMP-binding (23..430): X
  NRPSPredictor2: (unknown)
  SVM prediction details:
    NOTE: outside applicability domain
    Predicted physicochemical class:
      N/A
    Large clusters prediction:
      N/A
    Small clusters prediction:
      phe, trp
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      GfygfGAmGK
    Nearest Stachelhaus code:
      tcl
    Stachelhaus code match:
      50% (weak)

c00016_NZ_VSLA.. - Region 1 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 270,103 - 316,816 nt. (total: 46,714 nt) Show pHMM detection rules used
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000308.1 |  | 0.26 | NRP | aureusimine | Staphylococcus aureus subsp. aureus str. JKD6008
BGC0001575.1 |  | 0.25 | NRP | dipeptide aldehydes | Ruminococcus sp. 5_1_39BFAA
BGC0001627.1 |  | 0.22 | NRP | isonitrile lipopeptides | Mycobacterium tuberculosis H37Rv
BGC0001758.1 |  | 0.21 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001479.1 |  | 0.21 | NRP | anabaenopeptin NZ857, nostamide A | Nostoc punctiforme PCC 73102
BGC0001128.1 |  | 0.21 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001135.1 |  | 0.21 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0001825.1 |  | 0.21 | NRP | xenematide | Xenorhabdus nematophila AN6/1
BGC0001615.1 |  | 0.21 | NRP | hexose-palythine-serine, hexose-shinorine | Heteroscytonema crispum UCFS10
BGC0001833.1 |  | 0.21 | NRP | icosalide A, icosalide B | Burkholderia gladioli

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000308.1 |  | 0.59 | NRP | aureusimine | Staphylococcus aureus subsp. aureus str. JKD6008
BGC0001575.1 |  | 0.58 | NRP | dipeptide aldehydes | Ruminococcus sp. 5_1_39BFAA
BGC0001627.1 |  | 0.55 | NRP | isonitrile lipopeptides | Mycobacterium tuberculosis H37Rv
BGC0001758.1 |  | 0.54 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001479.1 |  | 0.53 | NRP | anabaenopeptin NZ857, nostamide A | Nostoc punctiforme PCC 73102
BGC0001128.1 |  | 0.53 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001135.1 |  | 0.53 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0001825.1 |  | 0.53 | NRP | xenematide | Xenorhabdus nematophila AN6/1
BGC0001615.1 |  | 0.53 | NRP | hexose-palythine-serine, hexose-shinorine | Heteroscytonema crispum UCFS10
BGC0001833.1 |  | 0.53 | NRP | icosalide A, icosalide B | Burkholderia gladioli

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 270102 - 316816:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (leu - X)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg16_259: leu - X
  Search NORINE for peptide: strict or relaxed
  AMP-binding (267..653): leu
  NRPSPredictor2: leu
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      gly, ala, val, leu, ile, abu, iva
    Small clusters prediction:
      val, leu, ile, abu, iva
    Single AA prediction:
      leu
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAmFsGLViK
    Nearest Stachelhaus code:
      leu
    Stachelhaus code match:
      70% (weak)
  AMP-binding (1262..1654): X
  NRPSPredictor2: hydrophobic-aromatic
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aromatic
    Large clusters prediction:
      N/A
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DALiiGAVeK
    Nearest Stachelhaus code:
      phe
    Stachelhaus code match:
      70% (weak)

c00023_NZ_VSLA.. - Region 1 - ranthipeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 98,063 - 119,412 nt. (total: 21,350 nt) Show pHMM detection rules used
ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | ranthipeptide | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001664.1 |  | 0.17 | Terpene | merosterol | Scytonema sp. PCC 10023
BGC0000665.1 |  | 0.15 | Terpene, Alkaloid | xiamycin | Streptomyces sp. HKI0576
BGC0001156.1 |  | 0.15 | Terpene | platencin | Streptomyces platensis
BGC0000666.1 |  | 0.15 | Terpene | xiamycin A | Streptomyces sp. SCSIO 02999
BGC0001140.1 |  | 0.15 | Terpene | platensimycin, platencin | Streptomyces platensis
BGC0001605.1 |  | 0.15 | Terpene | gibberellin | Sinorhizobium fredii NGR234
BGC0000906.1 |  | 0.14 | Other | heme D1 | Heliophilum fasciatum
BGC0000905.1 |  | 0.14 | Other | heme D1 | Heliobacillus mobilis
BGC0001914.1 |  | 0.13 | Other | benzastatin J, 7-hydroxyl benzastatin B, 7-hydroxyl O-demethylbenzastatin A, JBIR-67, 7-hydroxyl benzastatin F, 7-hydroxyl O-demethylbenzastatin D, O-demethylvirantmycin, 7-hydroxyl benzastatin D, virantmycin, benzastatin K, methylbenzastatin K | Streptomyces sp. RI18
BGC0001529.1 |  | 0.13 | Alkaloid | bezastatin derivates | Streptomyces sp. RI18

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001664.1 |  | 0.48 | Terpene | merosterol | Scytonema sp. PCC 10023
BGC0000665.1 |  | 0.45 | Terpene, Alkaloid | xiamycin | Streptomyces sp. HKI0576
BGC0001156.1 |  | 0.45 | Terpene | platencin | Streptomyces platensis
BGC0000666.1 |  | 0.45 | Terpene | xiamycin A | Streptomyces sp. SCSIO 02999
BGC0001140.1 |  | 0.45 | Terpene | platensimycin, platencin | Streptomyces platensis
BGC0001605.1 |  | 0.44 | Terpene | gibberellin | Sinorhizobium fredii NGR234
BGC0000906.1 |  | 0.44 | Other | heme D1 | Heliophilum fasciatum
BGC0000905.1 |  | 0.44 | Other | heme D1 | Heliobacillus mobilis
BGC0001914.1 |  | 0.41 | Other | benzastatin J, 7-hydroxyl benzastatin B, 7-hydroxyl O-demethylbenzastatin A, JBIR-67, 7-hydroxyl benzastatin F, 7-hydroxyl O-demethylbenzastatin D, O-demethylvirantmycin, 7-hydroxyl benzastatin D, virantmycin, benzastatin K, methylbenzastatin K | Streptomyces sp. RI18
BGC0001529.1 |  | 0.41 | Alkaloid | bezastatin derivates | Streptomyces sp. RI18

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00025_NZ_VSLA.. - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 70,183 - 91,043 nt. (total: 20,861 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000647.1 |  | 0.45 | Terpene | carotenoid | Rhodobacter sphaeroides
BGC0000650.1 |  | 0.27 | Terpene | carotenoid | Algoriphagus sp. KK10202C
BGC0000637.1 |  | 0.23 | Terpene | carotenoid | Corynebacterium glutamicum
BGC0000648.1 |  | 0.23 | Terpene | carotenoid | Myxococcus xanthus
BGC0000646.1 |  | 0.21 | Terpene | β-carotein | uncultured bacterium
BGC0001227.1 |  | 0.21 | Terpene | isorenieratene | Streptomyces collinus Tu 365
BGC0000644.1 |  | 0.21 | Terpene | carotenoid | Dietzia sp. CQ4
BGC0000640.1 |  | 0.21 | Terpene | carotenoid | Enterobacteriaceae bacterium DC404
BGC0000664.1 |  | 0.20 | Terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000633.1 |  | 0.20 | Terpene | carotenoid | Streptomyces avermitilis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000647.1 |  | 0.76 | Terpene | carotenoid | Rhodobacter sphaeroides
BGC0000650.1 |  | 0.60 | Terpene | carotenoid | Algoriphagus sp. KK10202C
BGC0000637.1 |  | 0.56 | Terpene | carotenoid | Corynebacterium glutamicum
BGC0000648.1 |  | 0.56 | Terpene | carotenoid | Myxococcus xanthus
BGC0000646.1 |  | 0.54 | Terpene | β-carotein | uncultured bacterium
BGC0001227.1 |  | 0.53 | Terpene | isorenieratene | Streptomyces collinus Tu 365
BGC0000644.1 |  | 0.53 | Terpene | carotenoid | Dietzia sp. CQ4
BGC0000640.1 |  | 0.53 | Terpene | carotenoid | Enterobacteriaceae bacterium DC404
BGC0000664.1 |  | 0.53 | Terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000633.1 |  | 0.53 | Terpene | carotenoid | Streptomyces avermitilis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

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Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
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Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
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