GCF_002055515.1_ASM205551v1_genomic - 8 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP020000.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	NRPS,hserlactone	101,682	143,859
Region 1.2	arylpolyene	516,995	558,996	APE Vf	Other	45%
Region 1.3	arylpolyene	819,011	860,240	berninamycin A	RiPP	26%
Region 1.4	betalactone	1,470,206	1,499,286	mycosubtilin	NRP + Polyketide	20%
Region 1.5	NRPS,redox-cofactor	1,919,944	1,974,827	lankacidin C	NRP + Polyketide	13%
Region 1.6	siderophore	2,357,793	2,374,220	staphylobactin	Other	12%
Region 1.7	NAPAA	3,144,517	3,178,515
Region 1.8	lassopeptide	3,473,947	3,496,405

Region	Type	From	To	Most similar known cluster	Similarity
Region 1.1	NRPS,hserlactone	101,682	143,859
Region 1.2	arylpolyene	516,995	558,996	APE Vf	Other	45%
Region 1.3	arylpolyene	819,011	860,240	berninamycin A	RiPP	26%
Region 1.4	betalactone	1,470,206	1,499,286	mycosubtilin	NRP + Polyketide	20%
Region 1.5	NRPS,redox-cofactor	1,919,944	1,974,827	lankacidin C	NRP + Polyketide	13%
Region 1.6	siderophore	2,357,793	2,374,220	staphylobactin	Other	12%
Region 1.7	NAPAA	3,144,517	3,178,515
Region 1.8	lassopeptide	3,473,947	3,496,405

No secondary metabolite regions were found in these records:: NZ_CP020001.1

Compact view

NZ_CP020000.1 - Region 1 - NRPS,hserlactone

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Location: 101,682 - 143,859 nt. (total: 42,178 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))
hserlactone: Autoind_synth

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NRPS/PKS domains

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NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001983.1	0.50	Other	triacsins	Kitasatospora aureofaciens
BGC0001831.1	0.47	Polyketide	alkylpyrone-407, alkylpyrone-393	Myxococcus xanthus DK 1622
BGC0001343.1	0.46	Polyketide	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0001458.1	0.43	Other (Aminocoumarin)	salinipostin G	Salinispora tropica CNB-440
BGC0000343.1	0.42	NRP	enterobactin	Pseudomonas sp. J465
BGC0000274.1	0.41	Polyketide	tetarimycin A, tetarimycin B	uncultured bacterium
BGC0002034.1	0.41	Other	perquinoline A, perquinoline B, perquinoline C	Streptomyces sp. IB2014 016-6
BGC0000220.1	0.41	Polyketide	enterocin	Streptomyces maritimus
BGC0001185.1	0.40	NRP	bacillibactin	Bacillus velezensis FZB42
BGC0000401.1	0.38	NRP	paenibactin	Paenibacillus elgii B69

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001890.1	0.65	NRP	amphi-enterobactin 1, amphi-enterobactin 2, amphi-enterobactin 3, amphi-enterobactin 4	Vibrio campbellii ATCC BAA-1116
BGC0001615.1	0.65	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0001399.1	0.64	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0001778.1	0.61	Other	showdomycin	Streptomyces showdoensis
BGC0001983.1	0.61	Other	triacsins	Kitasatospora aureofaciens
BGC0000389.1	0.60	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0001343.1	0.59	Polyketide	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0000417.1	0.58	NRP	rhodochelin	Rhodococcus jostii RHA1
BGC0002034.1	0.58	Other	perquinoline A, perquinoline B, perquinoline C	Streptomyces sp. IB2014 016-6
BGC0001185.1	0.58	NRP	bacillibactin	Bacillus velezensis FZB42

Similar known gene clusters

No matches found.

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Detailed TIGRFAM domain annotation

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 101681 - 143859:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_95

Search NORINE for peptide: strict or relaxed

AMP-binding (38..443): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: ayyaSAHmVK
Nearest Stachelhaus code:: pip
Stachelhaus code match:: 50% (weak)

ctg1_103

CAL_domain (154..486): pk

minowa: NH2

Prediction, score:

NH2: 123.2
Acetyl-CoA: 59.5
fatty_acid: 21.0
shikimic_acid: 0.0
AHBA: 0.0

ctg1_106

Search NORINE for peptide: strict or relaxed

AMP-binding (486..872): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGvVWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 90% (moderate)

NZ_CP020000.1 - Region 2 - arylpolyene

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Location: 516,995 - 558,996 nt. (total: 42,002 nt) Show pHMM detection rules used

arylpolyene: (APE_KS1 or APE_KS2)

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Pfam domains

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002008.1	0.29	Other	aryl polyenes	Xenorhabdus doucetiae
BGC0000836.1	0.28	Other	APE Ec	Escherichia coli CFT073
BGC0001723.1	0.24	Polyketide	oviedomycin	Streptomyces antibioticus
BGC0000231.1	0.24	Polyketide	griseusin	Streptomyces griseus
BGC0001591.1	0.23	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.23	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0000219.1	0.22	Polyketide, Saccharide	elloramycin	Streptomyces olivaceus
BGC0000234.1	0.22	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0000228.1	0.22	Polyketide	granaticin	Streptomyces violaceoruber
BGC0001366.1	0.22	Polyketide	BE-24566B, zunyimycin A	Streptomyces sp. FJS31-2

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002008.1	0.62	Other	aryl polyenes	Xenorhabdus doucetiae
BGC0000836.1	0.61	Other	APE Ec	Escherichia coli CFT073
BGC0001723.1	0.57	Polyketide	oviedomycin	Streptomyces antibioticus
BGC0000231.1	0.57	Polyketide	griseusin	Streptomyces griseus
BGC0001591.1	0.56	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.56	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0000219.1	0.56	Polyketide, Saccharide	elloramycin	Streptomyces olivaceus
BGC0000234.1	0.55	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0000228.1	0.55	Polyketide	granaticin	Streptomyces violaceoruber
BGC0001366.1	0.55	Polyketide	BE-24566B, zunyimycin A	Streptomyces sp. FJS31-2

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Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NZ_CP020000.1 - Region 3 - arylpolyene

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Location: 819,011 - 860,240 nt. (total: 41,230 nt) Show pHMM detection rules used

arylpolyene: (APE_KS1 or APE_KS2)

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Pfam domains

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000779.1	0.21	Saccharide	lipopolysaccharide	Aeromonas piscicola
BGC0000780.1	0.19	Saccharide	O&K-antigen	Vibrio parahaemolyticus
BGC0000906.1	0.15	Other	heme D1	Heliophilum fasciatum
BGC0000905.1	0.14	Other	heme D1	Heliobacillus mobilis
BGC0001897.1	0.14	Polyketide	cepacin A	Burkholderia ambifaria IOP40-10
BGC0001987.1	0.14	Polyketide	koreenceine A, koreenceine B, koreenceine C, koreenceine D	Pseudomonas koreensis
BGC0000234.1	0.14	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0002008.1	0.14	Other	aryl polyenes	Xenorhabdus doucetiae
BGC0001973.1	0.14	Other	fervenulin	Streptomyces hiroshimensis
BGC0001972.1	0.14	Other	toxoflavin, fervenulin	Streptomyces hiroshimensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000779.1	0.54	Saccharide	lipopolysaccharide	Aeromonas piscicola
BGC0000780.1	0.51	Saccharide	O&K-antigen	Vibrio parahaemolyticus
BGC0000906.1	0.45	Other	heme D1	Heliophilum fasciatum
BGC0000905.1	0.44	Other	heme D1	Heliobacillus mobilis
BGC0001897.1	0.44	Polyketide	cepacin A	Burkholderia ambifaria IOP40-10
BGC0001987.1	0.44	Polyketide	koreenceine A, koreenceine B, koreenceine C, koreenceine D	Pseudomonas koreensis
BGC0000234.1	0.43	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0002008.1	0.43	Other	aryl polyenes	Xenorhabdus doucetiae
BGC0001973.1	0.43	Other	fervenulin	Streptomyces hiroshimensis
BGC0001972.1	0.43	Other	toxoflavin, fervenulin	Streptomyces hiroshimensis

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Detailed TIGRFAM domain annotation

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NZ_CP020000.1 - Region 4 - betalactone

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Location: 1,470,206 - 1,499,286 nt. (total: 29,081 nt) Show pHMM detection rules used

betalactone: (HMGL-like and AMP-binding)

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000662.1	0.24	Terpene	grixazone	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001897.1	0.20	Polyketide	cepacin A	Burkholderia ambifaria IOP40-10
BGC0001399.1	0.20	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000890.1	0.20	Other (Aminocoumarin)	pentabromopseudilin	Pseudoalteromonas phenolica O-BC30
BGC0000891.1	0.20	Other (Aminocoumarin)	pentabromopseudilin	Pseudoalteromonas luteoviolacea 2ta16
BGC0000234.1	0.20	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0001940.1	0.17	Polyketide	pyxidicycline A, pyxidicycline B	Pyxidicoccus fallax
BGC0001983.1	0.17	Other	triacsins	Kitasatospora aureofaciens
BGC0000373.1	0.16	NRP	holomycin	Streptomyces clavuligerus ATCC 27064
BGC0001730.1	0.15	Polyketide	paramagnetoquinone 1, paramagnetoquinone 2	Actinoallomurus sp.

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000662.1	0.57	Terpene	grixazone	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001897.1	0.52	Polyketide	cepacin A	Burkholderia ambifaria IOP40-10
BGC0001399.1	0.52	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000890.1	0.52	Other (Aminocoumarin)	pentabromopseudilin	Pseudoalteromonas phenolica O-BC30
BGC0000891.1	0.52	Other (Aminocoumarin)	pentabromopseudilin	Pseudoalteromonas luteoviolacea 2ta16
BGC0000234.1	0.52	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0001940.1	0.48	Polyketide	pyxidicycline A, pyxidicycline B	Pyxidicoccus fallax
BGC0001983.1	0.48	Other	triacsins	Kitasatospora aureofaciens
BGC0000373.1	0.47	NRP	holomycin	Streptomyces clavuligerus ATCC 27064
BGC0001730.1	0.45	Polyketide	paramagnetoquinone 1, paramagnetoquinone 2	Actinoallomurus sp.

Similar known gene clusters

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Detailed TIGRFAM domain annotation

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NZ_CP020000.1 - Region 5 - NRPS,redox-cofactor

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Location: 1,919,944 - 1,974,827 nt. (total: 54,884 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))
redox-cofactor: (cds(PF04055 and (TIGR04085 or SPASM)) and (TIGR02111 or TIGR03966) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001733.1	0.50	RiPP	PcpA	Pleurocapsa sp. PCC 7327
BGC0000401.1	0.34	NRP	paenibactin	Paenibacillus elgii B69
BGC0001615.1	0.33	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0001207.1	0.32	NRP	teixobactin	Eleftheria terrae
BGC0000835.1	0.32	Polyketide	simocyclinone	Streptomyces antibioticus
BGC0000527.1	0.31	RiPP	mersacidin	Bacillus sp. HIL-Y85/54728
BGC0000292.1	0.31	NRP	acetylaranotin	Aspergillus terreus NIH2624
BGC0001498.1	0.29	Other	aerobactin	Xenorhabdus szentirmaii DSM 16338
BGC0000939.1	0.29	Other	aerobactin	Grimontia hollisae
BGC0000329.1	0.28	NRP	corpeptin A, corpeptin B	Pseudomonas corrugata

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000401.1	0.68	NRP	paenibactin	Paenibacillus elgii B69
BGC0001615.1	0.67	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0001184.1	0.61	Other	bacilysin	Bacillus velezensis FZB42
BGC0000888.1	0.61	Other	bacilysin	Bacillus sp. CS93
BGC0000410.1	0.60	NRP	pseudomonine	Pseudomonas fluorescens
BGC0001149.1	0.60	NRP, Saccharide	brabantamide A	Pseudomonas sp. SHC52
BGC0001833.1	0.60	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001132.1	0.60	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001825.1	0.59	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001733.1	0.59	RiPP	PcpA	Pleurocapsa sp. PCC 7327

Similar known gene clusters

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Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 6, location 1919943 - 1974827:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - ser)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 7, location 1919943 - 1967098:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - ser)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_1829

Search NORINE for peptide: strict or relaxed

AMP-binding (478..892): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DslDLGlVDK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 70% (weak)

AMP-binding (1538..1943): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

ctg1_1834

Search NORINE for peptide: strict or relaxed

AMP-binding (36..446): dhb

NRPSPredictor2: dhb

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: dhb, sal
Small clusters prediction:: dhb, sal
Single AA prediction:: dhb

Stachelhaus prediction details:

Stachelhaus sequence:: SMACQGVVNK
Nearest Stachelhaus code:: dhb
Stachelhaus code match:: 100% (strong)

NZ_CP020000.1 - Region 6 - siderophore

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Location: 2,357,793 - 2,374,220 nt. (total: 16,428 nt) Show pHMM detection rules used

siderophore: IucA_IucC

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core biosynthetic genes

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Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000295.1	0.30	NRP	acinetoferrin	Acinetobacter haemolyticus
BGC0001453.1	0.27	Other	desferrioxamine	Streptomyces argillaceus
BGC0000942.1	0.27	Other	petrobactin	Bacillus anthracis str. Ames
BGC0000946.1	0.22	Other	vibrioferrin	Vibrio parahaemolyticus
BGC0000939.1	0.19	Other	aerobactin	Grimontia hollisae
BGC0000943.1	0.17	Other	staphylobactin	Staphylococcus aureus subsp. aureus NCTC 8325
BGC0000896.1	0.14	Other	cycloserine	Streptomyces lavendulae subsp. lavendulae
BGC0000774.1	0.14	Saccharide	lipopolysaccharide	Xanthomonas campestris pv. campestris
BGC0001587.1	0.14	Other	ethylenediaminesuccinic acid hydroxyarginine (EDHA)	Streptomyces avermitilis MA-4680 = NBRC 14893
BGC0001122.1	0.11	NRP, Polyketide	dihydroisoflavipucine, isoflavipucine	Aspergillus terreus NIH2624

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000295.1	0.63	NRP	acinetoferrin	Acinetobacter haemolyticus
BGC0001453.1	0.61	Other	desferrioxamine	Streptomyces argillaceus
BGC0000942.1	0.61	Other	petrobactin	Bacillus anthracis str. Ames
BGC0000946.1	0.55	Other	vibrioferrin	Vibrio parahaemolyticus
BGC0000939.1	0.51	Other	aerobactin	Grimontia hollisae
BGC0000943.1	0.48	Other	staphylobactin	Staphylococcus aureus subsp. aureus NCTC 8325
BGC0000896.1	0.44	Other	cycloserine	Streptomyces lavendulae subsp. lavendulae
BGC0000774.1	0.44	Saccharide	lipopolysaccharide	Xanthomonas campestris pv. campestris
BGC0001587.1	0.43	Other	ethylenediaminesuccinic acid hydroxyarginine (EDHA)	Streptomyces avermitilis MA-4680 = NBRC 14893
BGC0001122.1	0.38	NRP, Polyketide	dihydroisoflavipucine, isoflavipucine	Aspergillus terreus NIH2624

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Detailed TIGRFAM domain annotation

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NZ_CP020000.1 - Region 7 - NAPAA

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Location: 3,144,517 - 3,178,515 nt. (total: 33,999 nt) Show pHMM detection rules used

NAPAA: (AMP-binding and PP-binding and TIGR02353)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001444.1	0.22	Other	caboxamycin	Streptomyces sp. NTK 937
BGC0001538.1	0.22	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0000375.1	0.22	NRP	indigoidine	Streptomyces chromofuscus
BGC0000427.1	0.21	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000888.1	0.21	Other	bacilysin	Bacillus sp. CS93
BGC0001399.1	0.20	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0001897.1	0.20	Polyketide	cepacin A	Burkholderia ambifaria IOP40-10
BGC0001197.1	0.20	Polyketide	frankiamicin	Frankia sp. EAN1pec
BGC0000761.1	0.18	Saccharide	exopolysaccharide	Methylobacillus sp. 12S
BGC0001479.1	0.18	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001444.1	0.55	Other	caboxamycin	Streptomyces sp. NTK 937
BGC0001538.1	0.55	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0000375.1	0.55	NRP	indigoidine	Streptomyces chromofuscus
BGC0000427.1	0.54	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000888.1	0.53	Other	bacilysin	Bacillus sp. CS93
BGC0001399.1	0.53	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0001897.1	0.52	Polyketide	cepacin A	Burkholderia ambifaria IOP40-10
BGC0001197.1	0.52	Polyketide	frankiamicin	Frankia sp. EAN1pec
BGC0000761.1	0.50	Saccharide	exopolysaccharide	Methylobacillus sp. 12S
BGC0001479.1	0.50	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102

Similar known gene clusters

No matches found.

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Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 10, location 3144516 - 3178515:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_2950

Search NORINE for peptide: strict or relaxed

AMP-binding (31..418): X

NRPSPredictor2: hydrophilic

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DmEHNgTVtK
Nearest Stachelhaus code:: dab
Stachelhaus code match:: 70% (weak)

NZ_CP020000.1 - Region 8 - lassopeptide

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Location: 3,473,947 - 3,496,405 nt. (total: 22,459 nt) Show pHMM detection rules used

lassopeptide: (PF13471 and Asn_synthase or micJ25 or mcjC)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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MIBiG comparison

KnownClusterBlast

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Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000571.1	0.32	RiPP	burhizin	Paraburkholderia rhizoxinica HKI 454
BGC0000580.1	0.31	RiPP	xanthomonin I, xanthomonin II	Xanthomonas gardneri ATCC 19865
BGC0000576.1	0.31	RiPP	rubrivinodin	Rubrivivax gelatinosus IL144
BGC0001494.1	0.27	RiPP	acinetodin	Acinetobacter gyllenbergii CIP 110306
BGC0000577.1	0.24	RiPP	sphingonodin II	Sphingobium japonicum UT26S
BGC0000574.1	0.23	RiPP	caulosegnin I, caulosegnin II, caulosegnin III	Caulobacter segnis ATCC 21756
BGC0001549.1	0.19	RiPP	citrulassin B	Streptomyces aurantiacus JA 4570
BGC0001550.1	0.19	RiPP	citrulassin D	Streptomyces katrae
BGC0000575.1	0.19	RiPP	lariatin	Rhodococcus jostii
BGC0001356.1	0.19	RiPP	paeninodin	Paenibacillus dendritiformis C454

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000571.1	0.65	RiPP	burhizin	Paraburkholderia rhizoxinica HKI 454
BGC0000580.1	0.64	RiPP	xanthomonin I, xanthomonin II	Xanthomonas gardneri ATCC 19865
BGC0000576.1	0.64	RiPP	rubrivinodin	Rubrivivax gelatinosus IL144
BGC0001494.1	0.61	RiPP	acinetodin	Acinetobacter gyllenbergii CIP 110306
BGC0000577.1	0.57	RiPP	sphingonodin II	Sphingobium japonicum UT26S
BGC0000574.1	0.56	RiPP	caulosegnin I, caulosegnin II, caulosegnin III	Caulobacter segnis ATCC 21756
BGC0001549.1	0.51	RiPP	citrulassin B	Streptomyces aurantiacus JA 4570
BGC0001550.1	0.51	RiPP	citrulassin D	Streptomyces katrae
BGC0000575.1	0.51	RiPP	lariatin	Rhodococcus jostii
BGC0001356.1	0.51	RiPP	paeninodin	Paenibacillus dendritiformis C454

Similar known gene clusters

No matches found.

Lasso peptide predictions

Lassopeptide(s) for ctg1_3227 - Putative Class II

ctg1_3227 leader / core peptide / cleaved tail: MNNNQVNNLIEDQDDVDLIFLGSVKDETK - GFDFEGTVEPRDFDKYNKDLQEIDSMP

Legend:

Red: Putative macrolactam
Purple: Putative cleaved off residues

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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Lasso peptides

Core peptide predictions

ctg1_3227 - Class II: Cleavage pHMM score: 7.90; RODEO score: 16; Monoisotopic mass: 3173.4 Da; Molecular weight: 3175.4 Da; Number of bridges: 0