GCF_000146185.1_ASM14618v1_genomic - 5 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NC_012778.1

Region	Type	From	To
Region 1.1	cyclic-lactone-autoinducer	641,336	667,089
Region 1.2	ranthipeptide	1,425,526	1,447,122
Region 1.3	betalactone	1,963,186	1,989,064

NC_012780.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 3.1	cyclic-lactone-autoinducer	36,948	55,354
Region 3.2	cyclic-lactone-autoinducer	58,689	84,141

Region	Type	From	To	Similarity
Region 1.1	cyclic-lactone-autoinducer	641,336	667,089
Region 1.2	ranthipeptide	1,425,526	1,447,122
Region 1.3	betalactone	1,963,186	1,989,064
Region 3.1	cyclic-lactone-autoinducer	36,948	55,354
Region 3.2	cyclic-lactone-autoinducer	58,689	84,141

No secondary metabolite regions were found in these records:: NC_012782.1

Compact view

NC_012778.1 - Region 1 - cyclic-lactone-autoinducer

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Location: 641,336 - 667,089 nt. (total: 25,754 nt) Show pHMM detection rules used

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000585.1	0.21	RiPP	microcin C7	Escherichia coli
BGC0001618.1	0.19	RiPP	hyicin 3682	Staphylococcus hyicus
BGC0000925.1	0.18	Other	quinolobactin	Pseudomonas fluorescens
BGC0000244.1	0.17	Polyketide	macrotetrolide	Streptomyces griseus subsp. griseus
BGC0000886.1	0.17	Other	allylmalonyl-CoA	Streptomyces tsukubensis
BGC0000917.1	0.17	Other	molybdenum cofactor	Rhodobacter capsulatus
BGC0000488.1	0.17	RiPP	circularin A	Clostridium beijerinckii
BGC0000514.1	0.16	RiPP	gallidermin	Staphylococcus gallinarum
BGC0000538.1	0.16	RiPP	nisin Z	Lactococcus lactis
BGC0001289.1	0.16	RiPP	penisin	Paenibacillus ehimensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000585.1	0.54	RiPP	microcin C7	Escherichia coli
BGC0001618.1	0.51	RiPP	hyicin 3682	Staphylococcus hyicus
BGC0000925.1	0.49	Other	quinolobactin	Pseudomonas fluorescens
BGC0000244.1	0.49	Polyketide	macrotetrolide	Streptomyces griseus subsp. griseus
BGC0000886.1	0.48	Other	allylmalonyl-CoA	Streptomyces tsukubensis
BGC0000917.1	0.48	Other	molybdenum cofactor	Rhodobacter capsulatus
BGC0000488.1	0.48	RiPP	circularin A	Clostridium beijerinckii
BGC0000514.1	0.46	RiPP	gallidermin	Staphylococcus gallinarum
BGC0000538.1	0.46	RiPP	nisin Z	Lactococcus lactis
BGC0001289.1	0.46	RiPP	penisin	Paenibacillus ehimensis

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NC_012778.1 - Region 2 - ranthipeptide

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Location: 1,425,526 - 1,447,122 nt. (total: 21,597 nt) Show pHMM detection rules used

ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000487.1	0.17	RiPP	carnocyclin	Carnobacterium maltaromaticum
BGC0000938.1	0.17	Other (Aminocoumarin)	fosfomycin	Streptomyces fradiae
BGC0000488.1	0.17	RiPP	circularin A	Clostridium beijerinckii
BGC0000542.1	0.16	RiPP	paenicidin B	Paenibacillus terrae
BGC0000554.1	0.16	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000541.1	0.16	RiPP	paenicidin A	Paenibacillus polymyxa
BGC0000504.1	0.16	RiPP	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0000601.1	0.16	RiPP	sporulation killing factor	Bacillus subtilis subsp. subtilis str. 168
BGC0000600.1	0.16	RiPP	thurincin H	Bacillus thuringiensis
BGC0001407.1	0.16	RiPP	bicereucin	Bacillus cereus SJ1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000487.1	0.48	RiPP	carnocyclin	Carnobacterium maltaromaticum
BGC0000938.1	0.48	Other (Aminocoumarin)	fosfomycin	Streptomyces fradiae
BGC0000488.1	0.48	RiPP	circularin A	Clostridium beijerinckii
BGC0000542.1	0.47	RiPP	paenicidin B	Paenibacillus terrae
BGC0000554.1	0.47	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000541.1	0.47	RiPP	paenicidin A	Paenibacillus polymyxa
BGC0000504.1	0.47	RiPP	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0000601.1	0.47	RiPP	sporulation killing factor	Bacillus subtilis subsp. subtilis str. 168
BGC0000600.1	0.47	RiPP	thurincin H	Bacillus thuringiensis
BGC0001407.1	0.47	RiPP	bicereucin	Bacillus cereus SJ1

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NC_012778.1 - Region 3 - betalactone

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Location: 1,963,186 - 1,989,064 nt. (total: 25,879 nt) Show pHMM detection rules used

betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000649.1	0.18	Terpene	carotenoid	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000701.1	0.16	Saccharide	jinggangmycin	Streptomyces hygroscopicus subsp. yingchengensis
BGC0000805.1	0.13	Saccharide	moenomycin	Streptomyces viridosporus ATCC 14672
BGC0001411.1	0.13	Saccharide	polysaccharide B	Bacteroides fragilis
BGC0001544.1	0.13	NRP, Polyketide	chlorflavonin	Aspergillus campestris IBT 28561
BGC0001627.1	0.12	NRP	isonitrile lipopeptides	Mycobacterium tuberculosis H37Rv
BGC0000353.1	0.12	NRP	tacrolimus	Streptomyces sp. MA6548
BGC0001298.1	0.10	Polyketide	4-Z-annimycin	Streptomyces calvus
BGC0001515.1	0.10	NRP	aspercryptins	Aspergillus nidulans FGSC A4
BGC0001007.1	0.09	Polyketide, NRP	lymphostin, neolymphostinol B, lymphostinol, neolymphostin b	Salinispora arenicola CNS-205

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000649.1	0.49	Terpene	carotenoid	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000701.1	0.46	Saccharide	jinggangmycin	Streptomyces hygroscopicus subsp. yingchengensis
BGC0000805.1	0.42	Saccharide	moenomycin	Streptomyces viridosporus ATCC 14672
BGC0001411.1	0.41	Saccharide	polysaccharide B	Bacteroides fragilis
BGC0001544.1	0.41	NRP, Polyketide	chlorflavonin	Aspergillus campestris IBT 28561
BGC0001627.1	0.40	NRP	isonitrile lipopeptides	Mycobacterium tuberculosis H37Rv
BGC0000353.1	0.40	NRP	tacrolimus	Streptomyces sp. MA6548
BGC0001298.1	0.36	Polyketide	4-Z-annimycin	Streptomyces calvus
BGC0001515.1	0.35	NRP	aspercryptins	Aspergillus nidulans FGSC A4
BGC0001007.1	0.34	Polyketide, NRP	lymphostin, neolymphostinol B, lymphostinol, neolymphostin b	Salinispora arenicola CNS-205

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NC_012780.1 - Region 1 - cyclic-lactone-autoinducer

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Location: 36,948 - 55,354 nt. (total: 18,407 nt) Show pHMM detection rules used

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002009.1	0.16	Polyketide	kanglemycin A, kanglemycin V1, kanglemycin V2	Amycolatopsis vancoresmycina
BGC0000518.1	0.16	RiPP	informatipeptin	Streptomyces viridochromogenes DSM 40736
BGC0001494.1	0.16	RiPP	acinetodin	Acinetobacter gyllenbergii CIP 110306
BGC0000571.1	0.15	RiPP	burhizin	Paraburkholderia rhizoxinica HKI 454
BGC0000486.1	0.15	RiPP	butyrivibriocin AR10	Butyrivibrio fibrisolvens
BGC0000617.1	0.15	RiPP	coagulin	Bacillus coagulans
BGC0001639.1	0.15	RiPP	klebsidin	Klebsiella pneumoniae
BGC0000620.1	0.15	RiPP	lacticin Q	Lactococcus lactis
BGC0000584.1	0.14	RiPP	colicin V	Escherichia coli
BGC0001484.1	0.13	Other	2'-chloropentostatin, 2'-amino-2'-deoxyadenosine	Actinomadura sp. ATCC 39365

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002009.1	0.47	Polyketide	kanglemycin A, kanglemycin V1, kanglemycin V2	Amycolatopsis vancoresmycina
BGC0000518.1	0.47	RiPP	informatipeptin	Streptomyces viridochromogenes DSM 40736
BGC0001494.1	0.46	RiPP	acinetodin	Acinetobacter gyllenbergii CIP 110306
BGC0000571.1	0.46	RiPP	burhizin	Paraburkholderia rhizoxinica HKI 454
BGC0000486.1	0.46	RiPP	butyrivibriocin AR10	Butyrivibrio fibrisolvens
BGC0000617.1	0.46	RiPP	coagulin	Bacillus coagulans
BGC0001639.1	0.45	RiPP	klebsidin	Klebsiella pneumoniae
BGC0000620.1	0.45	RiPP	lacticin Q	Lactococcus lactis
BGC0000584.1	0.43	RiPP	colicin V	Escherichia coli
BGC0001484.1	0.42	Other	2'-chloropentostatin, 2'-amino-2'-deoxyadenosine	Actinomadura sp. ATCC 39365

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NC_012780.1 - Region 2 - cyclic-lactone-autoinducer

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Location: 58,689 - 84,141 nt. (total: 25,453 nt) Show pHMM detection rules used

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001618.1	0.17	RiPP	hyicin 3682	Staphylococcus hyicus
BGC0001973.1	0.17	Other	fervenulin	Streptomyces hiroshimensis
BGC0001972.1	0.17	Other	toxoflavin, fervenulin	Streptomyces hiroshimensis
BGC0000488.1	0.17	RiPP	circularin A	Clostridium beijerinckii
BGC0000528.1	0.16	RiPP	michiganin A	Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0000538.1	0.16	RiPP	nisin Z	Lactococcus lactis
BGC0001289.1	0.16	RiPP	penisin	Paenibacillus ehimensis
BGC0000486.1	0.15	RiPP	butyrivibriocin AR10	Butyrivibrio fibrisolvens
BGC0000535.1	0.15	RiPP	nisin A	Lactococcus lactis subsp. lactis
BGC0000536.1	0.15	RiPP	nisin Q	Lactococcus lactis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001618.1	0.48	RiPP	hyicin 3682	Staphylococcus hyicus
BGC0001973.1	0.48	Other	fervenulin	Streptomyces hiroshimensis
BGC0001972.1	0.48	Other	toxoflavin, fervenulin	Streptomyces hiroshimensis
BGC0000488.1	0.47	RiPP	circularin A	Clostridium beijerinckii
BGC0000528.1	0.47	RiPP	michiganin A	Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0000538.1	0.46	RiPP	nisin Z	Lactococcus lactis
BGC0001289.1	0.46	RiPP	penisin	Paenibacillus ehimensis
BGC0000486.1	0.45	RiPP	butyrivibriocin AR10	Butyrivibrio fibrisolvens
BGC0000535.1	0.45	RiPP	nisin A	Lactococcus lactis subsp. lactis
BGC0000536.1	0.45	RiPP	nisin Q	Lactococcus lactis

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names