GCF_000422745.1_ASM42274v1_genomic - 5 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_AUGQ01000001 (original name was: NZ_AUGQ01000001.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	NRPS	334,067	388,726	fuscachelin A / fuscachelin B / fuscachelin C	NRP	66%

NZ_AUGQ01000002 (original name was: NZ_AUGQ01000002.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 2.1	NAPAA	18,481	52,164	formicamycins A-M	Polyketide	9%
Region 2.2	ectoine	274,142	284,531	ectoine	Other	75%

NZ_AUGQ01000013 (original name was: NZ_AUGQ01000013.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 12.1	terpene	9,964	30,848	carotenoid	Terpene	28%

NZ_AUGQ01000014 (original name was: NZ_AUGQ01000014.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 13.1	betalactone	1	20,399

No secondary metabolite regions were found in these records:: NZ_KE383914.1; NZ_AUGQ01000005 (original name was: NZ_AUGQ01000005.1); NZ_AUGQ01000006 (original name was: NZ_AUGQ01000006.1); NZ_AUGQ01000007 (original name was: NZ_AUGQ01000007.1); NZ_AUGQ01000008 (original name was: NZ_AUGQ01000008.1); NZ_AUGQ01000009 (original name was: NZ_AUGQ01000009.1); NZ_AUGQ01000010 (original name was: NZ_AUGQ01000010.1); NZ_AUGQ01000011 (original name was: NZ_AUGQ01000011.1); NZ_AUGQ01000012 (original name was: NZ_AUGQ01000012.1); NZ_AUGQ01000015 (original name was: NZ_AUGQ01000015.1); NZ_AUGQ01000016 (original name was: NZ_AUGQ01000016.1); NZ_AUGQ01000017 (original name was: NZ_AUGQ01000017.1); NZ_AUGQ01000018 (original name was: NZ_AUGQ01000018.1); NZ_AUGQ01000019 (original name was: NZ_AUGQ01000019.1); NZ_AUGQ01000020 (original name was: NZ_AUGQ01000020.1); NZ_AUGQ01000021 (original name was: NZ_AUGQ01000021.1); NZ_AUGQ01000022 (original name was: NZ_AUGQ01000022.1); NZ_AUGQ01000023 (original name was: NZ_AUGQ01000023.1); NZ_AUGQ01000024 (original name was: NZ_AUGQ01000024.1); NZ_AUGQ01000025 (original name was: NZ_AUGQ01000025.1); NZ_AUGQ01000026 (original name was: NZ_AUGQ01000026.1); NZ_AUGQ01000027 (original name was: NZ_AUGQ01000027.1); NZ_AUGQ01000028 (original name was: NZ_AUGQ01000028.1); NZ_AUGQ01000029 (original name was: NZ_AUGQ01000029.1); NZ_AUGQ01000030 (original name was: NZ_AUGQ01000030.1); NZ_AUGQ01000031 (original name was: NZ_AUGQ01000031.1); NZ_AUGQ01000032 (original name was: NZ_AUGQ01000032.1); NZ_AUGQ01000033 (original name was: NZ_AUGQ01000033.1); NZ_AUGQ01000034 (original name was: NZ_AUGQ01000034.1); NZ_AUGQ01000035 (original name was: NZ_AUGQ01000035.1); NZ_AUGQ01000036 (original name was: NZ_AUGQ01000036.1); NZ_AUGQ01000037 (original name was: NZ_AUGQ01000037.1); NZ_AUGQ01000038 (original name was: NZ_AUGQ01000038.1); NZ_AUGQ01000039 (original name was: NZ_AUGQ01000039.1); NZ_AUGQ01000040 (original name was: NZ_AUGQ01000040.1); NZ_AUGQ01000041 (original name was: NZ_AUGQ01000041.1); NZ_AUGQ01000042 (original name was: NZ_AUGQ01000042.1); NZ_AUGQ01000043 (original name was: NZ_AUGQ01000043.1); NZ_AUGQ01000044 (original name was: NZ_AUGQ01000044.1); NZ_AUGQ01000045 (original name was: NZ_AUGQ01000045.1); NZ_AUGQ01000046 (original name was: NZ_AUGQ01000046.1); NZ_AUGQ01000047 (original name was: NZ_AUGQ01000047.1); NZ_AUGQ01000048 (original name was: NZ_AUGQ01000048.1); NZ_AUGQ01000049 (original name was: NZ_AUGQ01000049.1); NZ_AUGQ01000050 (original name was: NZ_AUGQ01000050.1); NZ_AUGQ01000051 (original name was: NZ_AUGQ01000051.1); NZ_AUGQ01000052 (original name was: NZ_AUGQ01000052.1); NZ_AUGQ01000053 (original name was: NZ_AUGQ01000053.1); NZ_AUGQ01000054 (original name was: NZ_AUGQ01000054.1); NZ_AUGQ01000055 (original name was: NZ_AUGQ01000055.1); NZ_AUGQ01000056 (original name was: NZ_AUGQ01000056.1); NZ_AUGQ01000057 (original name was: NZ_AUGQ01000057.1); NZ_AUGQ01000058 (original name was: NZ_AUGQ01000058.1); NZ_AUGQ01000059 (original name was: NZ_AUGQ01000059.1); NZ_AUGQ01000060 (original name was: NZ_AUGQ01000060.1); NZ_AUGQ01000061 (original name was: NZ_AUGQ01000061.1); NZ_AUGQ01000062 (original name was: NZ_AUGQ01000062.1); NZ_AUGQ01000063 (original name was: NZ_AUGQ01000063.1); NZ_AUGQ01000064 (original name was: NZ_AUGQ01000064.1); NZ_AUGQ01000065 (original name was: NZ_AUGQ01000065.1); NZ_AUGQ01000066 (original name was: NZ_AUGQ01000066.1); NZ_AUGQ01000067 (original name was: NZ_AUGQ01000067.1); NZ_AUGQ01000068 (original name was: NZ_AUGQ01000068.1); NZ_AUGQ01000069 (original name was: NZ_AUGQ01000069.1); NZ_AUGQ01000070 (original name was: NZ_AUGQ01000070.1); NZ_AUGQ01000071 (original name was: NZ_AUGQ01000071.1); NZ_AUGQ01000072 (original name was: NZ_AUGQ01000072.1); NZ_AUGQ01000073 (original name was: NZ_AUGQ01000073.1); NZ_AUGQ01000074 (original name was: NZ_AUGQ01000074.1); NZ_AUGQ01000075 (original name was: NZ_AUGQ01000075.1)

Compact view

c00001_NZ_AUGQ.. - Region 1 - NRPS

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Location: 334,067 - 388,726 nt. (total: 54,660 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

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TTA codons

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Gene details

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NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001050.1	0.34	NRP, Polyketide	thalassospiramide A	Tistrella bauzanensis
BGC0000457.1	0.30	NRP	vicibactin	Rhizobium etli CFN 42
BGC0000901.1	0.29	Other	ferrichrome	Aspergillus niger
BGC0000438.1	0.27	NRP	syringopeptin 25A	Pseudomonas syringae pv. syringae
BGC0000313.1	0.27	NRP	beauvericin	Beauveria bassiana
BGC0000465.1	0.26	NRP	xenortide A, xenortide B, xenortide C, xenortide D	Xenorhabdus nematophila ATCC 19061
BGC0000389.1	0.26	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0000426.1	0.26	NRP	sevadicin	Paenibacillus larvae
BGC0000342.1	0.26	NRP	enniatin	Fusarium equiseti
BGC0001399.1	0.26	NRP	fellutamide B	Aspergillus nidulans FGSC A4

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001050.1	0.67	NRP, Polyketide	thalassospiramide A	Tistrella bauzanensis
BGC0000457.1	0.64	NRP	vicibactin	Rhizobium etli CFN 42
BGC0000901.1	0.62	Other	ferrichrome	Aspergillus niger
BGC0000438.1	0.60	NRP	syringopeptin 25A	Pseudomonas syringae pv. syringae
BGC0000313.1	0.60	NRP	beauvericin	Beauveria bassiana
BGC0000465.1	0.60	NRP	xenortide A, xenortide B, xenortide C, xenortide D	Xenorhabdus nematophila ATCC 19061
BGC0000389.1	0.60	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0000426.1	0.60	NRP	sevadicin	Paenibacillus larvae
BGC0000342.1	0.59	NRP	enniatin	Fusarium equiseti
BGC0001399.1	0.59	NRP	fellutamide B	Aspergillus nidulans FGSC A4

Similar known gene clusters

Module view

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Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 334066 - 388726:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ala-b) + (X) + (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_348

Search NORINE for peptide: strict or relaxed

AMP-binding (106..539): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: m-WgtSmIcK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 40% (weak)

ctg1_349

Search NORINE for peptide: strict or relaxed

AMP-binding (453..843): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DMyiAGLmWK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 70% (weak)

ctg1_350

Search NORINE for peptide: strict or relaxed

AMP-binding (1069..1441): ala-b

NRPSPredictor2: ala-b

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: IDTtvSSGDK
Nearest Stachelhaus code:: ala-b
Stachelhaus code match:: 80% (moderate)

ctg1_351

Search NORINE for peptide: strict or relaxed

AMP-binding (458..852): X

NRPSPredictor2: ser, thr, dhpg, hpg

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAWegGfVDK
Nearest Stachelhaus code:: glu
Stachelhaus code match:: 70% (weak)

ctg1_352

Search NORINE for peptide: strict or relaxed

AMP-binding (549..940): X

NRPSPredictor2: hydrophilic

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DLqHmgLIhK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 60% (weak)

ctg1_354

Search NORINE for peptide: strict or relaxed

AMP-binding (39..437): dhb

NRPSPredictor2: dhb

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: dhb, sal
Small clusters prediction:: dhb, sal
Single AA prediction:: dhb

Stachelhaus prediction details:

Stachelhaus sequence:: TMPSQGVVNK
Nearest Stachelhaus code:: dhb
Stachelhaus code match:: 100% (strong)

c00002_NZ_AUGQ.. - Region 1 - NAPAA

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Location: 18,481 - 52,164 nt. (total: 33,684 nt) Show pHMM detection rules used

NAPAA: (AMP-binding and PP-binding and TIGR02353)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001591.1	0.23	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.23	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0001441.1	0.22	Other	belactosin A, belactosin C	Streptomyces sp.
BGC0000375.1	0.22	NRP	indigoidine	Streptomyces chromofuscus
BGC0000343.1	0.22	NRP	enterobactin	Pseudomonas sp. J465
BGC0001343.1	0.21	Polyketide	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0000427.1	0.21	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000410.1	0.21	NRP	pseudomonine	Pseudomonas fluorescens
BGC0001399.1	0.21	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000823.1	0.19	Alkaloid	rebeccamycin	Lechevalieria aerocolonigenes

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001591.1	0.56	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.56	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0001441.1	0.55	Other	belactosin A, belactosin C	Streptomyces sp.
BGC0000375.1	0.55	NRP	indigoidine	Streptomyces chromofuscus
BGC0000343.1	0.55	NRP	enterobactin	Pseudomonas sp. J465
BGC0001343.1	0.54	Polyketide	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0000427.1	0.53	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000410.1	0.53	NRP	pseudomonine	Pseudomonas fluorescens
BGC0001399.1	0.53	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000823.1	0.52	Alkaloid	rebeccamycin	Lechevalieria aerocolonigenes

Similar known gene clusters

Module view

Legend

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 18480 - 52164:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg2_34

Search NORINE for peptide: strict or relaxed

AMP-binding (35..424): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: gly, ala
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAESIGtVvK
Nearest Stachelhaus code:: lys
Stachelhaus code match:: 80% (moderate)

c00002_NZ_AUGQ.. - Region 2 - ectoine

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Location: 274,142 - 284,531 nt. (total: 10,390 nt) Show pHMM detection rules used

ectoine: ectoine_synt

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

reset view

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Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000853.1	0.43	Other	ectoine	Streptomyces anulatus
BGC0000856.1	0.40	Other	ectoine	Methylophaga thalassica
BGC0000852.1	0.38	Other	ectoine	Sporosarcina pasteurii
BGC0000859.1	0.33	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000855.1	0.33	Other	ectoine	Methylomicrobium kenyense
BGC0000858.1	0.32	Other	ectoine	Methylobacter marinus
BGC0000860.1	0.26	Other	ectoine	Methylarcula marina
BGC0000857.1	0.26	Other	ectoine	Methylophaga alcalica
BGC0000854.1	0.25	Other	ectoine	Methylomicrobium alcaliphilum 20Z
BGC0000774.1	0.16	Saccharide	lipopolysaccharide	Xanthomonas campestris pv. campestris

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000853.1	0.74	Other	ectoine	Streptomyces anulatus
BGC0000856.1	0.72	Other	ectoine	Methylophaga thalassica
BGC0000852.1	0.70	Other	ectoine	Sporosarcina pasteurii
BGC0000859.1	0.66	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000855.1	0.66	Other	ectoine	Methylomicrobium kenyense
BGC0000858.1	0.66	Other	ectoine	Methylobacter marinus
BGC0000860.1	0.60	Other	ectoine	Methylarcula marina
BGC0000857.1	0.60	Other	ectoine	Methylophaga alcalica
BGC0000854.1	0.58	Other	ectoine	Methylomicrobium alcaliphilum 20Z
BGC0000774.1	0.47	Saccharide	lipopolysaccharide	Xanthomonas campestris pv. campestris

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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c00012_NZ_AUGQ.. - Region 1 - terpene

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Location: 9,964 - 30,848 nt. (total: 20,885 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000648.1	0.29	Terpene	carotenoid	Myxococcus xanthus
BGC0000650.1	0.25	Terpene	carotenoid	Algoriphagus sp. KK10202C
BGC0000637.1	0.21	Terpene	carotenoid	Corynebacterium glutamicum
BGC0000644.1	0.21	Terpene	carotenoid	Dietzia sp. CQ4
BGC0000656.1	0.18	Terpene	zeaxanthin	Xanthobacter autotrophicus Py2
BGC0001456.1	0.17	Terpene	isorenieratene	Streptomyces argillaceus
BGC0000207.1	0.16	Polyketide	chartreusin	Streptomyces chartreusis
BGC0001295.1	0.14	Other	cremeomycin	Streptomyces cremeus
BGC0001374.1	0.14	Other	thienodolin	Streptomyces albogriseolus
BGC0000812.1	0.13	Alkaloid	huperzine A	Shiraia sp. slf14

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000648.1	0.62	Terpene	carotenoid	Myxococcus xanthus
BGC0000650.1	0.59	Terpene	carotenoid	Algoriphagus sp. KK10202C
BGC0000637.1	0.54	Terpene	carotenoid	Corynebacterium glutamicum
BGC0000644.1	0.53	Terpene	carotenoid	Dietzia sp. CQ4
BGC0000656.1	0.50	Terpene	zeaxanthin	Xanthobacter autotrophicus Py2
BGC0001456.1	0.48	Terpene	isorenieratene	Streptomyces argillaceus
BGC0000207.1	0.46	Polyketide	chartreusin	Streptomyces chartreusis
BGC0001295.1	0.44	Other	cremeomycin	Streptomyces cremeus
BGC0001374.1	0.43	Other	thienodolin	Streptomyces albogriseolus
BGC0000812.1	0.42	Alkaloid	huperzine A	Shiraia sp. slf14

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

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c00013_NZ_AUGQ.. - Region 1 - betalactone

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Location: 1 - 20,399 nt. (total: 20,399 nt) Show pHMM detection rules used

Region on contig edge.

betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000853.1	0.27	Other	ectoine	Streptomyces anulatus
BGC0000855.1	0.27	Other	ectoine	Methylomicrobium kenyense
BGC0000858.1	0.27	Other	ectoine	Methylobacter marinus
BGC0000859.1	0.27	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000852.1	0.26	Other	ectoine	Sporosarcina pasteurii
BGC0000856.1	0.26	Other	ectoine	Methylophaga thalassica
BGC0000234.1	0.21	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0000857.1	0.21	Other	ectoine	Methylophaga alcalica
BGC0000860.1	0.21	Other	ectoine	Methylarcula marina
BGC0000854.1	0.20	Other	ectoine	Methylomicrobium alcaliphilum 20Z

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000853.1	0.61	Other	ectoine	Streptomyces anulatus
BGC0000855.1	0.60	Other	ectoine	Methylomicrobium kenyense
BGC0000858.1	0.60	Other	ectoine	Methylobacter marinus
BGC0000859.1	0.60	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000852.1	0.60	Other	ectoine	Sporosarcina pasteurii
BGC0000856.1	0.60	Other	ectoine	Methylophaga thalassica
BGC0000234.1	0.53	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0000857.1	0.53	Other	ectoine	Methylophaga alcalica
BGC0000860.1	0.53	Other	ectoine	Methylarcula marina
BGC0000854.1	0.53	Other	ectoine	Methylomicrobium alcaliphilum 20Z

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names