GCF_902375455.1_MGYG-HGUT-01486_genomic - 3 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

c00016_NZ_CABK.. (original name was: NZ_CABKTY010000017.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 16.1	NRPS-like	102,623	150,569	salinilactam	Polyketide	8%

c00020_NZ_CABK.. (original name was: NZ_CABKTY010000021.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 20.1	betalactone,terpene	345,609	395,858	herboxidiene	Polyketide	4%

c00023_NZ_CABK.. (original name was: NZ_CABKTY010000024.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 23.1	NRPS-like	258,412	302,059	acarviostatin I03 / acarviostatin II03 / acarviostatin III03 / acarviostatin IV03	Saccharide	7%

No secondary metabolite regions were found in these records:: c00001_NZ_CABK.. (original name was: NZ_CABKTY010000001.1); c00002_NZ_CABK.. (original name was: NZ_CABKTY010000002.1); c00003_NZ_CABK.. (original name was: NZ_CABKTY010000003.1); c00004_NZ_CABK.. (original name was: NZ_CABKTY010000004.1); c00005_NZ_CABK.. (original name was: NZ_CABKTY010000005.1); c00006_NZ_CABK.. (original name was: NZ_CABKTY010000006.1); c00007_NZ_CABK.. (original name was: NZ_CABKTY010000007.1); c00008_NZ_CABK.. (original name was: NZ_CABKTY010000009.1); c00009_NZ_CABK.. (original name was: NZ_CABKTY010000010.1); c00010_NZ_CABK.. (original name was: NZ_CABKTY010000011.1); c00011_NZ_CABK.. (original name was: NZ_CABKTY010000012.1); c00012_NZ_CABK.. (original name was: NZ_CABKTY010000013.1); c00013_NZ_CABK.. (original name was: NZ_CABKTY010000014.1); c00014_NZ_CABK.. (original name was: NZ_CABKTY010000015.1); c00015_NZ_CABK.. (original name was: NZ_CABKTY010000016.1); c00017_NZ_CABK.. (original name was: NZ_CABKTY010000018.1); c00018_NZ_CABK.. (original name was: NZ_CABKTY010000019.1); c00019_NZ_CABK.. (original name was: NZ_CABKTY010000020.1); c00021_NZ_CABK.. (original name was: NZ_CABKTY010000022.1); c00022_NZ_CABK.. (original name was: NZ_CABKTY010000023.1)

Compact view

c00016_NZ_CABK.. - Region 1 - NRPS-like

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Location: 102,623 - 150,569 nt. (total: 47,947 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001343.1	0.46	Polyketide	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0000340.1	0.45	NRP	echoside A, echoside B, echoside C, echoside D, echoside E	Streptomyces sp. LZ35
BGC0000389.1	0.44	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0000375.1	0.44	NRP	indigoidine	Streptomyces chromofuscus
BGC0000427.1	0.41	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000957.1	0.40	NRP, Polyketide	mycotrienin I	Streptomyces sp. XZQH13
BGC0001895.1	0.39	Polyketide	huanglongmycin A, huanglongmycin B, huanglongmycin C	Streptomyces sp. CB09001
BGC0001806.1	0.37	NRP	tolaasin A	Pseudomonas tolaasii
BGC0001940.1	0.37	Polyketide	pyxidicycline A, pyxidicycline B	Pyxidicoccus fallax
BGC0000905.1	0.37	Other	heme D1	Heliobacillus mobilis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001343.1	0.57	Polyketide	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0000340.1	0.56	NRP	echoside A, echoside B, echoside C, echoside D, echoside E	Streptomyces sp. LZ35
BGC0000389.1	0.55	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0000375.1	0.55	NRP	indigoidine	Streptomyces chromofuscus
BGC0001225.1	0.54	NRP	celesticetin	Streptomyces caelestis
BGC0000957.1	0.53	NRP, Polyketide	mycotrienin I	Streptomyces sp. XZQH13
BGC0000427.1	0.53	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001895.1	0.53	Polyketide	huanglongmycin A, huanglongmycin B, huanglongmycin C	Streptomyces sp. CB09001
BGC0001940.1	0.51	Polyketide	pyxidicycline A, pyxidicycline B	Pyxidicoccus fallax
BGC0001806.1	0.51	NRP	tolaasin A	Pseudomonas tolaasii

Similar known gene clusters

Module view

Legend

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 102622 - 150569:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X) + (X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 102622 - 143949:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X) + (X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 107986 - 150569:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X) + (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg16_131

Search NORINE for peptide: strict or relaxed

AMP-binding (44..448): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: haTvtArLIK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 50% (weak)

ctg16_134

Search NORINE for peptide: strict or relaxed

AMP-binding (28..420): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: hAmHtarLiK
Nearest Stachelhaus code:: hpg
Stachelhaus code match:: 40% (weak)

c00020_NZ_CABK.. - Region 1 - betalactone,terpene

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Location: 345,609 - 395,858 nt. (total: 50,250 nt) Show pHMM detection rules used

betalactone: (HMGL-like and AMP-binding)
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000243.1	0.33	Polyketide	macrotetrolide	Streptomyces griseus subsp. griseus
BGC0001779.1	0.33	RiPP	siamycin	Streptomyces nodosus
BGC0001210.1	0.31	RiPP	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0000939.1	0.29	Other	aerobactin	Grimontia hollisae
BGC0001498.1	0.29	Other	aerobactin	Xenorhabdus szentirmaii DSM 16338
BGC0000294.1	0.29	NRP	acinetobactin	Acinetobacter baumannii
BGC0000488.1	0.28	RiPP	circularin A	Clostridium beijerinckii
BGC0001311.1	0.28	RiPP	flavecins	Ruminococcus flavefaciens FD-1
BGC0000410.1	0.28	NRP	pseudomonine	Pseudomonas fluorescens
BGC0001684.1	0.26	Other	N-acyloxyacyl glutamine	Klebsiella variicola

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000646.1	0.57	Terpene	β-carotein	uncultured bacterium
BGC0000634.1	0.56	Terpene	carotenoid	Brevundimonas sp. SD212
BGC0000648.1	0.55	Terpene	carotenoid	Myxococcus xanthus
BGC0000249.1	0.54	Polyketide	nogalamycin	Streptomyces nogalater
BGC0000641.1	0.54	Terpene	carotenoid	Enterobacteriaceae bacterium DC416
BGC0000639.1	0.53	Terpene	carotenoid	Enterobacteriaceae bacterium DC260
BGC0000664.1	0.53	Terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000649.1	0.53	Terpene	carotenoid	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000938.1	0.50	Other (Aminocoumarin)	fosfomycin	Streptomyces fradiae
BGC0001897.1	0.50	Polyketide	cepacin A	Burkholderia ambifaria IOP40-10

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

c00023_NZ_CABK.. - Region 1 - NRPS-like

Download region GenBank file

Download region SVG

Location: 258,412 - 302,059 nt. (total: 43,648 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000375.1	0.34	NRP	indigoidine	Streptomyces chromofuscus
BGC0000427.1	0.32	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001249.1	0.28	NRP	dimethylcoprogen	Alternaria alternata
BGC0000900.1	0.28	Other	ferrichrome	Aspergillus oryzae
BGC0000348.1	0.27	NRP	ergovaline	Epichloe festucae var. lolii
BGC0000979.1	0.25	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E9
BGC0000980.1	0.25	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 22D11
BGC0001561.1	0.23	NRP	curacomycin	Streptomyces curacoi
BGC0001479.1	0.23	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001718.1	0.21	NRP	okaramine D	Aspergillus aculeatus ATCC 16872

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000375.1	0.67	NRP	indigoidine	Streptomyces chromofuscus
BGC0000427.1	0.65	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001249.1	0.62	NRP	dimethylcoprogen	Alternaria alternata
BGC0000900.1	0.61	Other	ferrichrome	Aspergillus oryzae
BGC0000348.1	0.61	NRP	ergovaline	Epichloe festucae var. lolii
BGC0000979.1	0.58	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E9
BGC0000980.1	0.58	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 22D11
BGC0001561.1	0.56	NRP	curacomycin	Streptomyces curacoi
BGC0001479.1	0.56	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001718.1	0.54	NRP	okaramine D	Aspergillus aculeatus ATCC 16872

Similar known gene clusters

Module view

Legend

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 258411 - 302059:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg23_220

Search NORINE for peptide: strict or relaxed

AMP-binding (26..397): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: gly, ala
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAESIGtVvK
Nearest Stachelhaus code:: lys
Stachelhaus code match:: 80% (moderate)