GCF_000327285.1_ASM32728v1_genomic - 3 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_HE998567.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	NRPS	955,360	1,001,743

NZ_HE998568.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 2.1	RRE-containing	64,328	84,606
Region 2.2	cyclic-lactone-autoinducer	353,455	374,012

Region	Type	From	To	Similarity
Region 1.1	NRPS	955,360	1,001,743
Region 2.1	RRE-containing	64,328	84,606
Region 2.2	cyclic-lactone-autoinducer	353,455	374,012

No secondary metabolite regions were found in these records:: NZ_HE998569.1; NZ_HE998570.1; NZ_HE998571.1; NZ_HE998572.1; NZ_HE998573.1; NZ_HE998574.1; NZ_HE998575.1; NZ_HE998576.1; NZ_HE998577.1; NZ_HE998578.1; NZ_HE998579.1; NZ_HE998580.1; NZ_HE998581.1

Compact view

NZ_HE998567.1 - Region 1 - NRPS

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Location: 955,360 - 1,001,743 nt. (total: 46,384 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001343.1	0.27	Polyketide	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0001585.1	0.26	Alkaloid	melinacidin IV	Escovopsis weberi
BGC0000321.1	0.26	NRP	chaetocin	Collariella virescens
BGC0000417.1	0.25	NRP	rhodochelin	Rhodococcus jostii RHA1
BGC0001123.1	0.25	NRP	aspirochlorine	Aspergillus oryzae RIB40
BGC0001771.1	0.25	NRP	scleric acid	Streptomyces sclerotialus
BGC0000343.1	0.24	NRP	enterobactin	Pseudomonas sp. J465
BGC0001185.1	0.24	NRP	bacillibactin	Bacillus velezensis FZB42
BGC0001149.1	0.23	NRP, Saccharide	brabantamide A	Pseudomonas sp. SHC52
BGC0001833.1	0.23	NRP	icosalide A, icosalide B	Burkholderia gladioli

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001343.1	0.61	Polyketide	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0001585.1	0.60	Alkaloid	melinacidin IV	Escovopsis weberi
BGC0000321.1	0.60	NRP	chaetocin	Collariella virescens
BGC0000417.1	0.59	NRP	rhodochelin	Rhodococcus jostii RHA1
BGC0001123.1	0.58	NRP	aspirochlorine	Aspergillus oryzae RIB40
BGC0001771.1	0.58	NRP	scleric acid	Streptomyces sclerotialus
BGC0000343.1	0.57	NRP	enterobactin	Pseudomonas sp. J465
BGC0001185.1	0.57	NRP	bacillibactin	Bacillus velezensis FZB42
BGC0001149.1	0.56	NRP, Saccharide	brabantamide A	Pseudomonas sp. SHC52
BGC0001833.1	0.56	NRP	icosalide A, icosalide B	Burkholderia gladioli

Similar known gene clusters

No matches found.

Module view

Legend

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 955359 - 1001743:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - pro)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_921

Search NORINE for peptide: strict or relaxed

AMP-binding (469..852): X

NRPSPredictor2: hydrophobic-aromatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAisLGqIgK
Nearest Stachelhaus code:: bht
Stachelhaus code match:: 60% (weak)

AMP-binding (1485..1863): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DvTqIvcVyK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 50% (weak)

ctg1_925

Search NORINE for peptide: strict or relaxed

AMP-binding (30..445): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: gLcrvGGPLK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 60% (weak)

NZ_HE998568.1 - Region 1 - RRE-containing

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Location: 64,328 - 84,606 nt. (total: 20,279 nt) Show pHMM detection rules used

RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000938.1	0.16	Other (Aminocoumarin)	fosfomycin	Streptomyces fradiae
BGC0000554.1	0.16	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000487.1	0.16	RiPP	carnocyclin	Carnobacterium maltaromaticum
BGC0001210.1	0.16	RiPP	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0000551.1	0.16	RiPP	SapB	Streptomyces coelicolor A3(2)
BGC0000602.1	0.16	RiPP	subtilosin A	Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0001526.1	0.16	Other	bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K	Synechocystis salina LEGE 06099
BGC0000626.1	0.16	RiPP	thuricin	Bacillus thuringiensis
BGC0000539.1	0.16	RiPP	nukacin ISK-1	Staphylococcus warneri
BGC0000501.1	0.15	RiPP	catenulipeptin	Catenulispora acidiphila DSM 44928

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000938.1	0.47	Other (Aminocoumarin)	fosfomycin	Streptomyces fradiae
BGC0000554.1	0.47	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000487.1	0.46	RiPP	carnocyclin	Carnobacterium maltaromaticum
BGC0001210.1	0.46	RiPP	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0000551.1	0.46	RiPP	SapB	Streptomyces coelicolor A3(2)
BGC0000602.1	0.46	RiPP	subtilosin A	Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0001526.1	0.46	Other	bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K	Synechocystis salina LEGE 06099
BGC0000626.1	0.46	RiPP	thuricin	Bacillus thuringiensis
BGC0000539.1	0.46	RiPP	nukacin ISK-1	Staphylococcus warneri
BGC0000501.1	0.46	RiPP	catenulipeptin	Catenulispora acidiphila DSM 44928

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NZ_HE998568.1 - Region 2 - cyclic-lactone-autoinducer

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Location: 353,455 - 374,012 nt. (total: 20,558 nt) Show pHMM detection rules used

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001314.1	0.17	Terpene	tirucalla	Arabidopsis thaliana
BGC0001484.1	0.13	Other	2'-chloropentostatin, 2'-amino-2'-deoxyadenosine	Actinomadura sp. ATCC 39365
BGC0000486.1	0.09	RiPP	butyrivibriocin AR10	Butyrivibrio fibrisolvens

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001314.1	0.48	Terpene	tirucalla	Arabidopsis thaliana
BGC0001484.1	0.41	Other	2'-chloropentostatin, 2'-amino-2'-deoxyadenosine	Actinomadura sp. ATCC 39365
BGC0000486.1	0.33	RiPP	butyrivibriocin AR10	Butyrivibrio fibrisolvens

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names