GCF_022647425.1_ASM2264742v1_genomic - 11 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

c00002_NZ_JALC.. (original name was: NZ_JALCKS010000002.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 2.1	betalactone	87,813	117,444

c00003_NZ_JALC.. (original name was: NZ_JALCKS010000003.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 3.1	ranthipeptide	12,010	33,470
Region 3.2	NRPS	178,432	206,340

c00013_NZ_JALC.. (original name was: NZ_JALCKS010000013.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 13.1	terpene	1	15,093

c00022_NZ_JALC.. (original name was: NZ_JALCKS010000022.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 22.1	NRPS	1	52,633
Region 22.2	proteusin	53,954	74,274

c00033_NZ_JALC.. (original name was: NZ_JALCKS010000033.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 33.1	T3PKS	1,646	42,704	molybdenum cofactor	Other	11%

c00035_NZ_JALC.. (original name was: NZ_JALCKS010000035.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 35.1	proteusin	16,145	36,465	S-layer glycan	Saccharide	8%

c00056_NZ_JALC.. (original name was: NZ_JALCKS010000056.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 56.1	NRPS	1	28,596	tyrocidine	NRP	31%

c00065_NZ_JALC.. (original name was: NZ_JALCKS010000065.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 65.1	LAP,RiPP-like	1	19,791

c00067_NZ_JALC.. (original name was: NZ_JALCKS010000067.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 67.1	cyclic-lactone-autoinducer	1	16,490

Region	Type	From	To	Most similar known cluster	Similarity
Region 2.1	betalactone	87,813	117,444
Region 3.1	ranthipeptide	12,010	33,470
Region 3.2	NRPS	178,432	206,340
Region 13.1	terpene	1	15,093
Region 22.1	NRPS	1	52,633
Region 22.2	proteusin	53,954	74,274
Region 33.1	T3PKS	1,646	42,704	molybdenum cofactor	Other	11%
Region 35.1	proteusin	16,145	36,465	S-layer glycan	Saccharide	8%
Region 56.1	NRPS	1	28,596	tyrocidine	NRP	31%
Region 65.1	LAP,RiPP-like	1	19,791
Region 67.1	cyclic-lactone-autoinducer	1	16,490

No secondary metabolite regions were found in these records:: c00001_NZ_JALC.. (original name was: NZ_JALCKS010000001.1); c00004_NZ_JALC.. (original name was: NZ_JALCKS010000004.1); c00005_NZ_JALC.. (original name was: NZ_JALCKS010000005.1); c00006_NZ_JALC.. (original name was: NZ_JALCKS010000006.1); c00007_NZ_JALC.. (original name was: NZ_JALCKS010000007.1); c00008_NZ_JALC.. (original name was: NZ_JALCKS010000008.1); c00009_NZ_JALC.. (original name was: NZ_JALCKS010000009.1); c00010_NZ_JALC.. (original name was: NZ_JALCKS010000010.1); c00011_NZ_JALC.. (original name was: NZ_JALCKS010000011.1); c00012_NZ_JALC.. (original name was: NZ_JALCKS010000012.1); c00014_NZ_JALC.. (original name was: NZ_JALCKS010000014.1); c00015_NZ_JALC.. (original name was: NZ_JALCKS010000015.1); c00016_NZ_JALC.. (original name was: NZ_JALCKS010000016.1); c00017_NZ_JALC.. (original name was: NZ_JALCKS010000017.1); c00018_NZ_JALC.. (original name was: NZ_JALCKS010000018.1); c00019_NZ_JALC.. (original name was: NZ_JALCKS010000019.1); c00020_NZ_JALC.. (original name was: NZ_JALCKS010000020.1); c00021_NZ_JALC.. (original name was: NZ_JALCKS010000021.1); c00023_NZ_JALC.. (original name was: NZ_JALCKS010000023.1); c00024_NZ_JALC.. (original name was: NZ_JALCKS010000024.1); c00025_NZ_JALC.. (original name was: NZ_JALCKS010000025.1); c00026_NZ_JALC.. (original name was: NZ_JALCKS010000026.1); c00027_NZ_JALC.. (original name was: NZ_JALCKS010000027.1); c00028_NZ_JALC.. (original name was: NZ_JALCKS010000028.1); c00029_NZ_JALC.. (original name was: NZ_JALCKS010000029.1); c00030_NZ_JALC.. (original name was: NZ_JALCKS010000030.1); c00031_NZ_JALC.. (original name was: NZ_JALCKS010000031.1); c00032_NZ_JALC.. (original name was: NZ_JALCKS010000032.1); c00034_NZ_JALC.. (original name was: NZ_JALCKS010000034.1); c00036_NZ_JALC.. (original name was: NZ_JALCKS010000036.1); c00037_NZ_JALC.. (original name was: NZ_JALCKS010000037.1); c00038_NZ_JALC.. (original name was: NZ_JALCKS010000038.1); c00039_NZ_JALC.. (original name was: NZ_JALCKS010000039.1); c00040_NZ_JALC.. (original name was: NZ_JALCKS010000040.1); c00041_NZ_JALC.. (original name was: NZ_JALCKS010000041.1); c00042_NZ_JALC.. (original name was: NZ_JALCKS010000042.1); c00043_NZ_JALC.. (original name was: NZ_JALCKS010000043.1); c00044_NZ_JALC.. (original name was: NZ_JALCKS010000044.1); c00045_NZ_JALC.. (original name was: NZ_JALCKS010000045.1); c00046_NZ_JALC.. (original name was: NZ_JALCKS010000046.1); c00047_NZ_JALC.. (original name was: NZ_JALCKS010000047.1); c00048_NZ_JALC.. (original name was: NZ_JALCKS010000048.1); c00049_NZ_JALC.. (original name was: NZ_JALCKS010000049.1); c00050_NZ_JALC.. (original name was: NZ_JALCKS010000050.1); c00051_NZ_JALC.. (original name was: NZ_JALCKS010000051.1); c00052_NZ_JALC.. (original name was: NZ_JALCKS010000052.1); c00053_NZ_JALC.. (original name was: NZ_JALCKS010000053.1); c00054_NZ_JALC.. (original name was: NZ_JALCKS010000054.1); c00055_NZ_JALC.. (original name was: NZ_JALCKS010000055.1); c00057_NZ_JALC.. (original name was: NZ_JALCKS010000057.1); c00058_NZ_JALC.. (original name was: NZ_JALCKS010000058.1); c00059_NZ_JALC.. (original name was: NZ_JALCKS010000059.1); c00060_NZ_JALC.. (original name was: NZ_JALCKS010000060.1); c00061_NZ_JALC.. (original name was: NZ_JALCKS010000061.1); c00062_NZ_JALC.. (original name was: NZ_JALCKS010000062.1); c00063_NZ_JALC.. (original name was: NZ_JALCKS010000063.1); c00064_NZ_JALC.. (original name was: NZ_JALCKS010000064.1); c00066_NZ_JALC.. (original name was: NZ_JALCKS010000066.1); c00068_NZ_JALC.. (original name was: NZ_JALCKS010000068.1); c00069_NZ_JALC.. (original name was: NZ_JALCKS010000069.1); c00070_NZ_JALC.. (original name was: NZ_JALCKS010000070.1); c00071_NZ_JALC.. (original name was: NZ_JALCKS010000071.1); c00072_NZ_JALC.. (original name was: NZ_JALCKS010000072.1); c00073_NZ_JALC.. (original name was: NZ_JALCKS010000073.1); c00074_NZ_JALC.. (original name was: NZ_JALCKS010000074.1); c00075_NZ_JALC.. (original name was: NZ_JALCKS010000075.1); c00076_NZ_JALC.. (original name was: NZ_JALCKS010000076.1); c00077_NZ_JALC.. (original name was: NZ_JALCKS010000077.1); c00078_NZ_JALC.. (original name was: NZ_JALCKS010000078.1); c00079_NZ_JALC.. (original name was: NZ_JALCKS010000079.1); c00080_NZ_JALC.. (original name was: NZ_JALCKS010000080.1); c00081_NZ_JALC.. (original name was: NZ_JALCKS010000081.1); c00082_NZ_JALC.. (original name was: NZ_JALCKS010000082.1); c00083_NZ_JALC.. (original name was: NZ_JALCKS010000083.1); c00084_NZ_JALC.. (original name was: NZ_JALCKS010000084.1); c00085_NZ_JALC.. (original name was: NZ_JALCKS010000085.1); c00086_NZ_JALC.. (original name was: NZ_JALCKS010000086.1); c00087_NZ_JALC.. (original name was: NZ_JALCKS010000087.1); c00088_NZ_JALC.. (original name was: NZ_JALCKS010000088.1); c00089_NZ_JALC.. (original name was: NZ_JALCKS010000089.1); c00090_NZ_JALC.. (original name was: NZ_JALCKS010000090.1); c00091_NZ_JALC.. (original name was: NZ_JALCKS010000091.1); c00092_NZ_JALC.. (original name was: NZ_JALCKS010000092.1); c00093_NZ_JALC.. (original name was: NZ_JALCKS010000093.1); c00094_NZ_JALC.. (original name was: NZ_JALCKS010000094.1)

Compact view

c00002_NZ_JALC.. - Region 1 - betalactone

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Location: 87,813 - 117,444 nt. (total: 29,632 nt) Show pHMM detection rules used

betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000234.1	0.19	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0001808.1	0.17	Other	toyocamycin	Streptomyces diastatochromogenes
BGC0000881.1	0.17	Other	toyocamycin	Streptomyces ahygroscopicus subsp. wuzhouensis
BGC0000879.1	0.17	Other	toyocamycin, sangivamycin	Streptomyces rimosus
BGC0001937.1	0.17	Other	tubercidin	Streptomyces tubercidicus
BGC0000938.1	0.16	Other (Aminocoumarin)	fosfomycin	Streptomyces fradiae
BGC0000554.1	0.16	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0001241.1	0.16	Terpene	ergotamine	Claviceps fusiformis
BGC0001267.1	0.16	Terpene	lysergic acid, elymoclavine	Claviceps fusiformis
BGC0001391.1	0.16	RiPP	thusin	Bacillus thuringiensis serovar rongseni

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000234.1	0.51	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0001808.1	0.49	Other	toyocamycin	Streptomyces diastatochromogenes
BGC0000881.1	0.49	Other	toyocamycin	Streptomyces ahygroscopicus subsp. wuzhouensis
BGC0000879.1	0.49	Other	toyocamycin, sangivamycin	Streptomyces rimosus
BGC0001937.1	0.48	Other	tubercidin	Streptomyces tubercidicus
BGC0000938.1	0.47	Other (Aminocoumarin)	fosfomycin	Streptomyces fradiae
BGC0000554.1	0.47	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0001241.1	0.47	Terpene	ergotamine	Claviceps fusiformis
BGC0001267.1	0.47	Terpene	lysergic acid, elymoclavine	Claviceps fusiformis
BGC0001391.1	0.46	RiPP	thusin	Bacillus thuringiensis serovar rongseni

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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c00003_NZ_JALC.. - Region 1 - ranthipeptide

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Location: 12,010 - 33,470 nt. (total: 21,461 nt) Show pHMM detection rules used

ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000928.1	0.16	Other	T3 toxin	Cylindrospermopsis raciborskii T3
BGC0000188.1	0.16	Alkaloid	saxitoxin, neosaxitoxin, decarbamoylsaxitoxin, gonyautoxin 3, gonyautoxin 2	Cylindrospermopsis raciborskii T3
BGC0000486.1	0.16	RiPP	butyrivibriocin AR10	Butyrivibrio fibrisolvens
BGC0001787.1	0.16	RiPP	suicin 3908	Streptococcus suis
BGC0000498.1	0.16	RiPP	bovicin HJ50	Streptococcus equinus
BGC0000561.1	0.16	RiPP	thermophilin 1277	Streptococcus thermophilus
BGC0000626.1	0.16	RiPP	thuricin	Bacillus thuringiensis
BGC0000602.1	0.15	RiPP	subtilosin A	Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0001222.1	0.15	RiPP	acidocin B	Lactobacillus acidophilus
BGC0000491.1	0.15	RiPP	gassericin A	Lactobacillus gasseri

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000928.1	0.47	Other	T3 toxin	Cylindrospermopsis raciborskii T3
BGC0000188.1	0.47	Alkaloid	saxitoxin, neosaxitoxin, decarbamoylsaxitoxin, gonyautoxin 3, gonyautoxin 2	Cylindrospermopsis raciborskii T3
BGC0000486.1	0.46	RiPP	butyrivibriocin AR10	Butyrivibrio fibrisolvens
BGC0001787.1	0.46	RiPP	suicin 3908	Streptococcus suis
BGC0000498.1	0.46	RiPP	bovicin HJ50	Streptococcus equinus
BGC0000561.1	0.46	RiPP	thermophilin 1277	Streptococcus thermophilus
BGC0000626.1	0.46	RiPP	thuricin	Bacillus thuringiensis
BGC0000602.1	0.46	RiPP	subtilosin A	Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0001222.1	0.45	RiPP	acidocin B	Lactobacillus acidophilus
BGC0000491.1	0.45	RiPP	gassericin A	Lactobacillus gasseri

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

c00003_NZ_JALC.. - Region 2 - NRPS

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Location: 178,432 - 206,340 nt. (total: 27,909 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001399.1	0.30	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0001479.1	0.22	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0000427.1	0.22	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001128.1	0.22	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001833.1	0.22	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001135.1	0.21	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001641.1	0.21	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001758.1	0.21	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001615.1	0.21	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0001131.1	0.21	NRP	ambactin	Xenorhabdus miraniensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001399.1	0.64	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0001479.1	0.55	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0000427.1	0.55	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001128.1	0.55	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001833.1	0.55	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001135.1	0.54	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001641.1	0.54	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001758.1	0.54	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001615.1	0.54	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0001131.1	0.54	NRP	ambactin	Xenorhabdus miraniensis

Similar known gene clusters

No matches found.

Module view

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Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 178431 - 206340:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (tyr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg3_171

Search NORINE for peptide: strict or relaxed

AMP-binding (257..667): tyr

NRPSPredictor2: tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: N/A
Single AA prediction:: tyr

Stachelhaus prediction details:

Stachelhaus sequence:: DAaAIAAVgK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 80% (moderate)

ctg3_173

Search NORINE for peptide: strict or relaxed

AMP-binding (8..409): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: hcaftGLpGK
Nearest Stachelhaus code:: phg
Stachelhaus code match:: 40% (weak)

c00013_NZ_JALC.. - Region 1 - terpene

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Location: 1 - 15,093 nt. (total: 15,093 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001839.1	0.32	Terpene	squalestatin S1	Aspergillus sp. Z5
BGC0000888.1	0.16	Other	bacilysin	Bacillus sp. CS93
BGC0001138.1	0.15	Other (Nucleoside)	a201a	Marinactinospora thermotolerans
BGC0000207.1	0.15	Polyketide	chartreusin	Streptomyces chartreusis
BGC0001184.1	0.15	Other	bacilysin	Bacillus velezensis FZB42
BGC0000698.1	0.15	Saccharide	hygromycin A	Streptomyces hygroscopicus
BGC0001917.1	0.15	Polyketide	5-alkyl-1,2,3,4-tetrahydroquinolines, streptoaminals	Streptomyces nigrescens
BGC0000265.1	0.15	Polyketide	rhodomycin	Streptomyces purpurascens
BGC0000867.1	0.15	Other	polyhydroxyalkanoic acids	Ectothiorhodospira shaposhnikovii
BGC0000010.1	0.15	Polyketide	aflatoxin	Aspergillus flavus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001839.1	0.65	Terpene	squalestatin S1	Aspergillus sp. Z5
BGC0000888.1	0.47	Other	bacilysin	Bacillus sp. CS93
BGC0001138.1	0.46	Other (Nucleoside)	a201a	Marinactinospora thermotolerans
BGC0000207.1	0.46	Polyketide	chartreusin	Streptomyces chartreusis
BGC0001184.1	0.45	Other	bacilysin	Bacillus velezensis FZB42
BGC0000698.1	0.45	Saccharide	hygromycin A	Streptomyces hygroscopicus
BGC0001917.1	0.45	Polyketide	5-alkyl-1,2,3,4-tetrahydroquinolines, streptoaminals	Streptomyces nigrescens
BGC0000265.1	0.45	Polyketide	rhodomycin	Streptomyces purpurascens
BGC0000867.1	0.44	Other	polyhydroxyalkanoic acids	Ectothiorhodospira shaposhnikovii
BGC0000010.1	0.44	Polyketide	aflatoxin	Aspergillus flavus

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

c00022_NZ_JALC.. - Region 1 - NRPS

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Location: 1 - 52,633 nt. (total: 52,633 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000389.1	0.26	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0001538.1	0.25	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0001444.1	0.22	Other	caboxamycin	Streptomyces sp. NTK 937
BGC0001636.1	0.22	NRP	KK-1	Curvularia clavata
BGC0001699.1	0.21	Polyketide	nidulanin A	Aspergillus nidulans FGSC A4
BGC0001343.1	0.21	Polyketide	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0001591.1	0.21	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.21	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0001615.1	0.21	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0001220.1	0.21	NRP	aculeacin A	Aspergillus japonicus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000389.1	0.60	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0001538.1	0.58	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0001444.1	0.55	Other	caboxamycin	Streptomyces sp. NTK 937
BGC0001636.1	0.55	NRP	KK-1	Curvularia clavata
BGC0001699.1	0.54	Polyketide	nidulanin A	Aspergillus nidulans FGSC A4
BGC0001343.1	0.54	Polyketide	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0001591.1	0.54	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.54	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0001615.1	0.53	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0001220.1	0.53	NRP	aculeacin A	Aspergillus japonicus

Similar known gene clusters

No matches found.

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Detailed TIGRFAM domain annotation

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 52633:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Me-cys - Me-cys) + (Me-cys)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg22_12

Search NORINE for peptide: strict or relaxed

AMP-binding (538..933): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNLSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)

ctg22_15

Search NORINE for peptide: strict or relaxed

AMP-binding (568..967): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNMSMIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)

AMP-binding (2036..2437): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNLSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)

ctg22_16

Search NORINE for peptide: strict or relaxed

AMP-binding (32..435): dhb

NRPSPredictor2: dhb

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: dhb, sal
Small clusters prediction:: dhb, sal
Single AA prediction:: dhb

Stachelhaus prediction details:

Stachelhaus sequence:: PLPAQGViCK
Nearest Stachelhaus code:: dhb
Stachelhaus code match:: 90% (moderate)

c00022_NZ_JALC.. - Region 2 - proteusin

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Location: 53,954 - 74,274 nt. (total: 20,321 nt) Show pHMM detection rules used

proteusin: (PoyD or TIGR03793)

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001120.1	0.13	NRP, Polyketide	burkholderic acid	Burkholderia thailandensis E264
BGC0001596.1	0.11	Polyketide	fluostatins M-Q	Streptomyces albus
BGC0001636.1	0.09	NRP	KK-1	Curvularia clavata
BGC0000937.1	0.09	Other	fosfazinomycin A	Streptomyces sp. WM6372
BGC0001669.1	0.09	RiPP	microvionin	Microbacterium arborescens
BGC0001497.1	0.07	Polyketide	actinonin	Streptomyces sp.
BGC0001442.1	0.07	NRP	actinonin	Streptomyces sp. strain ATCC 14903
BGC0001580.1	0.07	Polyketide	ebelactone	Kitasatospora aburaviensis
BGC0000350.1	0.06	NRP	ET-743	uncultured organism
BGC0000609.1	0.06	RiPP	nocathiacin	Nocardia sp. ATCC 202099

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001120.1	0.42	NRP, Polyketide	burkholderic acid	Burkholderia thailandensis E264
BGC0001596.1	0.38	Polyketide	fluostatins M-Q	Streptomyces albus
BGC0001636.1	0.34	NRP	KK-1	Curvularia clavata
BGC0000937.1	0.33	Other	fosfazinomycin A	Streptomyces sp. WM6372
BGC0001669.1	0.33	RiPP	microvionin	Microbacterium arborescens
BGC0001497.1	0.29	Polyketide	actinonin	Streptomyces sp.
BGC0001442.1	0.29	NRP	actinonin	Streptomyces sp. strain ATCC 14903
BGC0001580.1	0.28	Polyketide	ebelactone	Kitasatospora aburaviensis
BGC0000350.1	0.27	NRP	ET-743	uncultured organism
BGC0000609.1	0.27	RiPP	nocathiacin	Nocardia sp. ATCC 202099

Similar known gene clusters

No matches found.

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Detailed TIGRFAM domain annotation

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c00033_NZ_JALC.. - Region 1 - T3PKS

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Location: 1,646 - 42,704 nt. (total: 41,059 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000282.1	0.27	Polyketide	alkylresorcinol	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001962.1	0.24	Polyketide	hierridin B, hierridin C	Cyanobium sp. LEGE 06113
BGC0001938.1	0.23	Polyketide	entotheonella	Candidatus Entotheonella serta
BGC0001535.1	0.22	Other	branched-chain fatty acids	Streptomyces filamentosus
BGC0001831.1	0.20	Polyketide	alkylpyrone-407, alkylpyrone-393	Myxococcus xanthus DK 1622
BGC0000867.1	0.18	Other	polyhydroxyalkanoic acids	Ectothiorhodospira shaposhnikovii
BGC0000866.1	0.18	Other	polyhydroxyalkanoate	Burkholderia sp. DSM 9242
BGC0001589.1	0.17	Saccharide	exopolysaccharides	Burkholderia cenocepacia J2315
BGC0001588.1	0.17	Saccharide	exopolysaccharides	Burkholderia pseudomallei 1026b
BGC0000626.1	0.16	RiPP	thuricin	Bacillus thuringiensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000282.1	0.60	Polyketide	alkylresorcinol	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001962.1	0.57	Polyketide	hierridin B, hierridin C	Cyanobium sp. LEGE 06113
BGC0001938.1	0.56	Polyketide	entotheonella	Candidatus Entotheonella serta
BGC0001535.1	0.55	Other	branched-chain fatty acids	Streptomyces filamentosus
BGC0001831.1	0.52	Polyketide	alkylpyrone-407, alkylpyrone-393	Myxococcus xanthus DK 1622
BGC0000867.1	0.49	Other	polyhydroxyalkanoic acids	Ectothiorhodospira shaposhnikovii
BGC0000866.1	0.49	Other	polyhydroxyalkanoate	Burkholderia sp. DSM 9242
BGC0001589.1	0.48	Saccharide	exopolysaccharides	Burkholderia cenocepacia J2315
BGC0001588.1	0.47	Saccharide	exopolysaccharides	Burkholderia pseudomallei 1026b
BGC0000626.1	0.47	RiPP	thuricin	Bacillus thuringiensis

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c00035_NZ_JALC.. - Region 1 - proteusin

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Location: 16,145 - 36,465 nt. (total: 20,321 nt) Show pHMM detection rules used

proteusin: (PoyD or TIGR03793)

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Analysis type:

Reference	proteusin	Similarity score	Type	Compound(s)	Organism
BGC0000795.1		0.14	Saccharide	S-layer glycan	Aneurinibacillus thermoaerophilus
BGC0001133.1		0.05	NRP	taxlllaid A	Xenorhabdus bovienii SS-2004

Reference	Aggregated	Similarity score	Type	Compound(s)	Organism
BGC0000795.1		0.44	Saccharide	S-layer glycan	Aneurinibacillus thermoaerophilus
BGC0001133.1		0.22	NRP	taxlllaid A	Xenorhabdus bovienii SS-2004

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c00056_NZ_JALC.. - Region 1 - NRPS

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Location: 1 - 28,596 nt. (total: 28,596 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000426.1	0.45	NRP	sevadicin	Paenibacillus larvae
BGC0000389.1	0.41	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0001050.1	0.37	NRP, Polyketide	thalassospiramide A	Tistrella bauzanensis
BGC0001615.1	0.36	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0001833.1	0.35	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0000417.1	0.33	NRP	rhodochelin	Rhodococcus jostii RHA1
BGC0000396.1	0.32	NRP	nodularin	Nostoc sp. 73.1
BGC0001128.1	0.31	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001825.1	0.31	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001758.1	0.31	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000426.1	0.75	NRP	sevadicin	Paenibacillus larvae
BGC0000389.1	0.73	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0001050.1	0.70	NRP, Polyketide	thalassospiramide A	Tistrella bauzanensis
BGC0001615.1	0.68	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0001833.1	0.68	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0000417.1	0.66	NRP	rhodochelin	Rhodococcus jostii RHA1
BGC0000396.1	0.65	NRP	nodularin	Nostoc sp. 73.1
BGC0001128.1	0.65	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001825.1	0.64	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001758.1	0.64	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 28596:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-phe) + (pro - val - orn - leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg56_7

Search NORINE for peptide: strict or relaxed

AMP-binding (35..427): phe

NRPSPredictor2: phe

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: phe, trp
Single AA prediction:: phe

Stachelhaus prediction details:

Stachelhaus sequence:: DAWTvAAICK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 90% (moderate)

ctg56_8

Search NORINE for peptide: strict or relaxed

AMP-binding (473..869): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: DVQSIAHVVK
Nearest Stachelhaus code:: pro
Stachelhaus code match:: 100% (strong)

AMP-binding (1511..1904): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAFfIGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 90% (moderate)

AMP-binding (2547..2949): orn

NRPSPredictor2: orn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: orn, lys, arg
Small clusters prediction:: orn, horn
Single AA prediction:: orn

Stachelhaus prediction details:

Stachelhaus sequence:: DVGEIGSIDK
Nearest Stachelhaus code:: orn
Stachelhaus code match:: 100% (strong)

AMP-binding (3593..3987): leu

NRPSPredictor2: leu

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DGAYTGEVVK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 100% (strong)

c00065_NZ_JALC.. - Region 1 - LAP,RiPP-like

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Location: 1 - 19,791 nt. (total: 19,791 nt) Show pHMM detection rules used

Region on contig edge.

LAP: ((((goadsporin_like or PF00881 or TIGR03605) and (YcaO or TIGR03882 or TIGR03604)) or TIGR03603 or TIGR03602) and not cyanobactin_synth)
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

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Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000607.1	0.52	RiPP	micrococcin P1	Macrococcus caseolyticus
BGC0000569.1	0.40	RiPP	plantazolicin	Bacillus velezensis FZB42
BGC0001173.1	0.40	RiPP	plantazolicin	Bacillus pumilus ATCC 7061
BGC0001146.1	0.39	RiPP	cyclothiazomycin C	Streptomyces sp. NRRL WC-3908
BGC0000483.1	0.39	RiPP	aeruginosamide B, aeruginosamide C	Microcystis aeruginosa PCC 9432
BGC0001145.1	0.33	RiPP	cyclothiazomycin b1	Streptomyces mobaraensis NBRC 13819 = DSM 40847
BGC0001849.1	0.33	RiPP	thiovarsolin A, thiovarsolin B, thiovarsolin C, thiovarsolin D	Streptomyces varsoviensis
BGC0000628.1	0.32	RiPP	lactocillin	Lactobacillus paragasseri JV-V03
BGC0000475.1	0.31	RiPP	patellamide A, patellamide C	Prochloron didemni
BGC0000480.1	0.31	RiPP	tenuecyclamide A, tenuecyclamide C	Nostoc spongiaeforme var. tenue str. Carmeli

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000607.1	0.59	RiPP	micrococcin P1	Macrococcus caseolyticus
BGC0000569.1	0.53	RiPP	plantazolicin	Bacillus velezensis FZB42
BGC0001173.1	0.53	RiPP	plantazolicin	Bacillus pumilus ATCC 7061
BGC0001146.1	0.52	RiPP	cyclothiazomycin C	Streptomyces sp. NRRL WC-3908
BGC0000483.1	0.52	RiPP	aeruginosamide B, aeruginosamide C	Microcystis aeruginosa PCC 9432
BGC0000628.1	0.50	RiPP	lactocillin	Lactobacillus paragasseri JV-V03
BGC0001145.1	0.48	RiPP	cyclothiazomycin b1	Streptomyces mobaraensis NBRC 13819 = DSM 40847
BGC0001849.1	0.47	RiPP	thiovarsolin A, thiovarsolin B, thiovarsolin C, thiovarsolin D	Streptomyces varsoviensis
BGC0001472.1	0.46	RiPP	berninamycin A	Streptomyces bernensis
BGC0000475.1	0.46	RiPP	patellamide A, patellamide C	Prochloron didemni

Similar known gene clusters

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c00067_NZ_JALC.. - Region 1 - cyclic-lactone-autoinducer

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Location: 1 - 16,490 nt. (total: 16,490 nt) Show pHMM detection rules used

Region on contig edge.

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

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Analysis type:

Reference	cyclic-lactone-autoinducer	Similarity score	Type	Compound(s)	Organism
BGC0001457.1		0.03	NRP	jomthonic acid A, jomthonic acid B, jomthonic acid C	Streptomyces caniferus

Reference	Aggregated	Similarity score	Type	Compound(s)	Organism
BGC0001457.1		0.16	NRP	jomthonic acid A, jomthonic acid B, jomthonic acid C	Streptomyces caniferus

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