GCF_019890915.1_ASM1989091v1_genomic - 6 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP082331.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	ectoine	270,502	280,873
Region 1.2	RRE-containing	574,426	594,758
Region 1.3	siderophore	1,130,982	1,142,817
Region 1.4	betalactone	1,488,206	1,515,168	microansamycin	Polyketide	7%
Region 1.5	NAPAA	1,545,575	1,579,336	stenothricin	NRP:Cyclic depsipeptide	31%
Region 1.6	terpene	2,248,012	2,268,908	carotenoid	Terpene	66%

Region	Type	From	To	Most similar known cluster	Similarity
Region 1.1	ectoine	270,502	280,873
Region 1.2	RRE-containing	574,426	594,758
Region 1.3	siderophore	1,130,982	1,142,817
Region 1.4	betalactone	1,488,206	1,515,168	microansamycin	Polyketide	7%
Region 1.5	NAPAA	1,545,575	1,579,336	stenothricin	NRP:Cyclic depsipeptide	31%
Region 1.6	terpene	2,248,012	2,268,908	carotenoid	Terpene	66%

No secondary metabolite regions were found in these records:: NZ_CP082332.1

Compact view

NZ_CP082331.1 - Region 1 - ectoine

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Location: 270,502 - 280,873 nt. (total: 10,372 nt) Show pHMM detection rules used

ectoine: ectoine_synt

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001778.1	0.35	Other	showdomycin	Streptomyces showdoensis
BGC0001844.1	0.14	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0000193.1	0.14	Polyketide	aclacinomycin	Streptomyces galilaeus
BGC0000891.1	0.14	Other (Aminocoumarin)	pentabromopseudilin	Pseudoalteromonas luteoviolacea 2ta16
BGC0000890.1	0.14	Other (Aminocoumarin)	pentabromopseudilin	Pseudoalteromonas phenolica O-BC30
BGC0001463.1	0.13	Other	2,3,4,5-tetrabromopyrrole	Pseudoalteromonas piscicida
BGC0001241.1	0.13	Terpene	ergotamine	Claviceps fusiformis
BGC0001267.1	0.13	Terpene	lysergic acid, elymoclavine	Claviceps fusiformis
BGC0001343.1	0.11	Polyketide	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0001006.1	0.10	NRP, Polyketide	lymphostin, neolymphostinol B, lymphostinol, neolymphostin B	Salinispora tropica CNB-440

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001778.1	0.68	Other	showdomycin	Streptomyces showdoensis
BGC0001844.1	0.43	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0000193.1	0.43	Polyketide	aclacinomycin	Streptomyces galilaeus
BGC0000891.1	0.43	Other (Aminocoumarin)	pentabromopseudilin	Pseudoalteromonas luteoviolacea 2ta16
BGC0000890.1	0.43	Other (Aminocoumarin)	pentabromopseudilin	Pseudoalteromonas phenolica O-BC30
BGC0001463.1	0.42	Other	2,3,4,5-tetrabromopyrrole	Pseudoalteromonas piscicida
BGC0001241.1	0.42	Terpene	ergotamine	Claviceps fusiformis
BGC0001267.1	0.42	Terpene	lysergic acid, elymoclavine	Claviceps fusiformis
BGC0001343.1	0.38	Polyketide	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0001006.1	0.37	NRP, Polyketide	lymphostin, neolymphostinol B, lymphostinol, neolymphostin B	Salinispora tropica CNB-440

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NZ_CP082331.1 - Region 2 - RRE-containing

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Location: 574,426 - 594,758 nt. (total: 20,333 nt) Show pHMM detection rules used

RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001894.1	0.17	Saccharide	heteropolysaccharide (HePS)	Lactobacillus plantarum
BGC0000780.1	0.14	Saccharide	O&K-antigen	Vibrio parahaemolyticus
BGC0000763.1	0.13	Saccharide	stewartan	Pantoea stewartii subsp. stewartii DC283
BGC0001812.1	0.04	Polyketide	tylactone	Micromonospora chalcea subsp. izumensis
BGC0000362.1	0.03	NRP	glycopeptidolipid	Mycobacterium avium

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001894.1	0.48	Saccharide	heteropolysaccharide (HePS)	Lactobacillus plantarum
BGC0000780.1	0.44	Saccharide	O&K-antigen	Vibrio parahaemolyticus
BGC0000763.1	0.42	Saccharide	stewartan	Pantoea stewartii subsp. stewartii DC283
BGC0001812.1	0.17	Polyketide	tylactone	Micromonospora chalcea subsp. izumensis
BGC0000362.1	0.16	NRP	glycopeptidolipid	Mycobacterium avium

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

Selected features only

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NZ_CP082331.1 - Region 3 - siderophore

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Location: 1,130,982 - 1,142,817 nt. (total: 11,836 nt) Show pHMM detection rules used

siderophore: IucA_IucC

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001478.1	0.50	Other	desferrioxamine E	Streptomyces sp. ID38640
BGC0000941.1	0.41	Other	desferrioxamin B	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001453.1	0.34	Other	desferrioxamine	Streptomyces argillaceus
BGC0001572.1	0.31	Other	desferrioxamine E	Pantoea agglomerans
BGC0000940.1	0.25	Other	desferrioxamin B, desferrioxamine E	Streptomyces coelicolor A3(2)
BGC0001499.1	0.17	Other	aerobactin	Pantoea ananatis
BGC0001531.1	0.17	Other	bisucaberin B	Tenacibaculum mesophilum
BGC0001713.1	0.16	Other	ochrobactin	Ochrobactrum anthropi
BGC0000244.1	0.16	Polyketide	macrotetrolide	Streptomyces griseus subsp. griseus
BGC0001985.1	0.15	Other	pyrazomycin	Streptomyces candidus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001478.1	0.78	Other	desferrioxamine E	Streptomyces sp. ID38640
BGC0000941.1	0.73	Other	desferrioxamin B	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001453.1	0.67	Other	desferrioxamine	Streptomyces argillaceus
BGC0001572.1	0.64	Other	desferrioxamine E	Pantoea agglomerans
BGC0000940.1	0.59	Other	desferrioxamin B, desferrioxamine E	Streptomyces coelicolor A3(2)
BGC0001499.1	0.49	Other	aerobactin	Pantoea ananatis
BGC0001531.1	0.48	Other	bisucaberin B	Tenacibaculum mesophilum
BGC0001713.1	0.46	Other	ochrobactin	Ochrobactrum anthropi
BGC0000244.1	0.46	Polyketide	macrotetrolide	Streptomyces griseus subsp. griseus
BGC0001985.1	0.45	Other	pyrazomycin	Streptomyces candidus

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

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NZ_CP082331.1 - Region 4 - betalactone

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Location: 1,488,206 - 1,515,168 nt. (total: 26,963 nt) Show pHMM detection rules used

betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000889.1	0.23	Other	bagremycin A, bagremycin B	Streptomyces sp. WK-5344
BGC0000649.1	0.23	Terpene	carotenoid	Streptomyces griseus subsp. griseus NBRC 13350
BGC0002029.1	0.21	Other	bagremycin A, bagremycin B, bagremycin C, bagremycin E, bagremycin F, bagremycin G, ferroverdin A, ferroverdin B, ferroverdin C	Streptomyces lunaelactis
BGC0001592.1	0.21	Other	ferroverdin	Streptomyces lunaelactis
BGC0001483.1	0.20	Other	5-isoprenylindole-3-carboxylate β-D-glycosyl ester	Streptomyces sp. RM-5-8
BGC0001935.1	0.19	Other	3,7-dihydroxytropolone	Streptomyces cyaneofuscatus
BGC0001487.1	0.19	Other	3,7-dihydroxytropolone	Streptomyces cyaneofuscatus
BGC0001387.1	0.19	Other	nucleocidin	Streptomyces calvus
BGC0000698.1	0.18	Saccharide	hygromycin A	Streptomyces hygroscopicus
BGC0002009.1	0.18	Polyketide	kanglemycin A, kanglemycin V1, kanglemycin V2	Amycolatopsis vancoresmycina

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000889.1	0.56	Other	bagremycin A, bagremycin B	Streptomyces sp. WK-5344
BGC0000649.1	0.56	Terpene	carotenoid	Streptomyces griseus subsp. griseus NBRC 13350
BGC0002029.1	0.54	Other	bagremycin A, bagremycin B, bagremycin C, bagremycin E, bagremycin F, bagremycin G, ferroverdin A, ferroverdin B, ferroverdin C	Streptomyces lunaelactis
BGC0001592.1	0.54	Other	ferroverdin	Streptomyces lunaelactis
BGC0001483.1	0.52	Other	5-isoprenylindole-3-carboxylate β-D-glycosyl ester	Streptomyces sp. RM-5-8
BGC0001935.1	0.51	Other	3,7-dihydroxytropolone	Streptomyces cyaneofuscatus
BGC0001487.1	0.51	Other	3,7-dihydroxytropolone	Streptomyces cyaneofuscatus
BGC0001387.1	0.51	Other	nucleocidin	Streptomyces calvus
BGC0000698.1	0.50	Saccharide	hygromycin A	Streptomyces hygroscopicus
BGC0002009.1	0.49	Polyketide	kanglemycin A, kanglemycin V1, kanglemycin V2	Amycolatopsis vancoresmycina

Similar known gene clusters

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NZ_CP082331.1 - Region 5 - NAPAA

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Location: 1,545,575 - 1,579,336 nt. (total: 33,762 nt) Show pHMM detection rules used

NAPAA: (AMP-binding and PP-binding and TIGR02353)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000858.1	0.23	Other	ectoine	Methylobacter marinus
BGC0000855.1	0.23	Other	ectoine	Methylomicrobium kenyense
BGC0000852.1	0.23	Other	ectoine	Sporosarcina pasteurii
BGC0000859.1	0.23	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000856.1	0.23	Other	ectoine	Methylophaga thalassica
BGC0000375.1	0.21	NRP	indigoidine	Streptomyces chromofuscus
BGC0001399.1	0.21	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000719.1	0.21	Saccharide	tobramycin	Streptoalloteichus hindustanus
BGC0000427.1	0.20	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000723.1	0.19	Saccharide	β-D-galactosylvalidoxylamine-A	Streptomyces hygroscopicus subsp. limoneus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000858.1	0.57	Other	ectoine	Methylobacter marinus
BGC0000855.1	0.56	Other	ectoine	Methylomicrobium kenyense
BGC0000852.1	0.56	Other	ectoine	Sporosarcina pasteurii
BGC0000859.1	0.56	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000856.1	0.56	Other	ectoine	Methylophaga thalassica
BGC0000375.1	0.54	NRP	indigoidine	Streptomyces chromofuscus
BGC0001399.1	0.54	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000719.1	0.53	Saccharide	tobramycin	Streptoalloteichus hindustanus
BGC0000427.1	0.53	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000723.1	0.52	Saccharide	β-D-galactosylvalidoxylamine-A	Streptomyces hygroscopicus subsp. limoneus

Similar known gene clusters

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Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 5, location 1545574 - 1579336:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_1365

Search NORINE for peptide: strict or relaxed

AMP-binding (0..337): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAESIGtVvK
Nearest Stachelhaus code:: lys
Stachelhaus code match:: 80% (moderate)

NZ_CP082331.1 - Region 6 - terpene

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Location: 2,248,012 - 2,268,908 nt. (total: 20,897 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000644.1	0.35	Terpene	carotenoid	Dietzia sp. CQ4
BGC0000645.1	0.30	Terpene	carotenoid	Halobacillus halophilus DSM 2266
BGC0000650.1	0.28	Terpene	carotenoid	Algoriphagus sp. KK10202C
BGC0000664.1	0.21	Terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000648.1	0.21	Terpene	carotenoid	Myxococcus xanthus
BGC0000637.1	0.20	Terpene	carotenoid	Corynebacterium glutamicum
BGC0001456.1	0.19	Terpene	isorenieratene	Streptomyces argillaceus
BGC0000649.1	0.19	Terpene	carotenoid	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000663.1	0.17	Terpene	hopene	Streptomyces coelicolor A3(2)
BGC0001521.1	0.17	NRP	auriculamide	Herpetosiphon aurantiacus DSM 785

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000644.1	0.68	Terpene	carotenoid	Dietzia sp. CQ4
BGC0000645.1	0.64	Terpene	carotenoid	Halobacillus halophilus DSM 2266
BGC0000650.1	0.62	Terpene	carotenoid	Algoriphagus sp. KK10202C
BGC0000664.1	0.54	Terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000648.1	0.54	Terpene	carotenoid	Myxococcus xanthus
BGC0000637.1	0.53	Terpene	carotenoid	Corynebacterium glutamicum
BGC0001456.1	0.51	Terpene	isorenieratene	Streptomyces argillaceus
BGC0000649.1	0.51	Terpene	carotenoid	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000663.1	0.48	Terpene	hopene	Streptomyces coelicolor A3(2)
BGC0001521.1	0.48	NRP	auriculamide	Herpetosiphon aurantiacus DSM 785

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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