GCF_000196855.1_ASM19685v1_genomic - 3 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NC_014319.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	furan	46,659	67,597	methylenomycin A	Other	9%
Region 2	T3PKS	895,294	936,454
Region 3	hglE-KS	1,848,497	1,890,977

NC_014319.1 - Region 1 - furan

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Location: 46,659 - 67,597 nt. (total: 20,939 nt) Show pHMM detection rules used

furan: (mmyO or AvrD)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000487.1	0.17	RiPP	carnocyclin	Carnobacterium maltaromaticum
BGC0001526.1	0.17	Other	bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K	Synechocystis salina LEGE 06099
BGC0001525.1	0.16	Other	bartoloside 2, bartoloside 3, bartoloside 4	Synechocystis salina LEGE 06155
BGC0000502.1	0.16	RiPP	cerecidin, cerecidin A1, cerecidin A2, cerecidin A3, cerecidin A4, cerecidin A5, cerecidin A6, cerecidin A7	Bacillus cereus
BGC0001407.1	0.16	RiPP	bicereucin	Bacillus cereus SJ1
BGC0000554.1	0.16	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0001210.1	0.16	RiPP	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0000516.1	0.16	RiPP	geobacillin II	Geobacillus thermodenitrificans
BGC0001660.1	0.16	RiPP	mathermycin	Marinactinospora thermotolerans
BGC0001579.1	0.16	RiPP	duramycin	Streptomyces cinnamoneus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000487.1	0.48	RiPP	carnocyclin	Carnobacterium maltaromaticum
BGC0001526.1	0.48	Other	bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K	Synechocystis salina LEGE 06099
BGC0001525.1	0.47	Other	bartoloside 2, bartoloside 3, bartoloside 4	Synechocystis salina LEGE 06155
BGC0000502.1	0.47	RiPP	cerecidin, cerecidin A1, cerecidin A2, cerecidin A3, cerecidin A4, cerecidin A5, cerecidin A6, cerecidin A7	Bacillus cereus
BGC0001407.1	0.47	RiPP	bicereucin	Bacillus cereus SJ1
BGC0000554.1	0.47	RiPP	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0001210.1	0.47	RiPP	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0000516.1	0.46	RiPP	geobacillin II	Geobacillus thermodenitrificans
BGC0001660.1	0.46	RiPP	mathermycin	Marinactinospora thermotolerans
BGC0001579.1	0.46	RiPP	duramycin	Streptomyces cinnamoneus

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

Expand to show all names

NC_014319.1 - Region 2 - T3PKS

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Location: 895,294 - 936,454 nt. (total: 41,161 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000286.1	0.22	Polyketide	viguiepinol	Streptomyces sp. KO-3988
BGC0000255.1	0.20	Polyketide	pederin	Uncultured bacterium
BGC0001120.1	0.16	NRP, Polyketide	burkholderic acid	Burkholderia thailandensis E264
BGC0000720.1	0.16	Saccharide	tobramycin	Streptoalloteichus tenebrarius
BGC0001104.1	0.16	NRP, Polyketide	myxovirescin A1	Myxococcus xanthus DK 1622
BGC0000719.1	0.16	Saccharide	tobramycin	Streptoalloteichus hindustanus
BGC0000880.1	0.15	Other (Nucleoside)	tunicamycin B1	Streptomyces chartreusis NRRL 3882
BGC0000874.1	0.15	Other	blasticidin S	Streptomyces griseochromogenes
BGC0001591.1	0.14	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.14	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000286.1	0.55	Polyketide	viguiepinol	Streptomyces sp. KO-3988
BGC0000255.1	0.53	Polyketide	pederin	Uncultured bacterium
BGC0001120.1	0.47	NRP, Polyketide	burkholderic acid	Burkholderia thailandensis E264
BGC0000720.1	0.46	Saccharide	tobramycin	Streptoalloteichus tenebrarius
BGC0001104.1	0.46	NRP, Polyketide	myxovirescin A1	Myxococcus xanthus DK 1622
BGC0000719.1	0.46	Saccharide	tobramycin	Streptoalloteichus hindustanus
BGC0000880.1	0.46	Other (Nucleoside)	tunicamycin B1	Streptomyces chartreusis NRRL 3882
BGC0000874.1	0.44	Other	blasticidin S	Streptomyces griseochromogenes
BGC0001591.1	0.44	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.44	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NC_014319.1 - Region 3 - hglE-KS

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Location: 1,848,497 - 1,890,977 nt. (total: 42,481 nt) Show pHMM detection rules used

hglE-KS: (hglE or hglD)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000044.1	0.18	Polyketide	dawenol	Stigmatella aurantiaca DW4/3-1
BGC0000410.1	0.17	NRP	pseudomonine	Pseudomonas fluorescens
BGC0001579.1	0.17	RiPP	duramycin	Streptomyces cinnamoneus
BGC0001364.1	0.17	RiPP	cinnamycin B	Actinomadura atramentaria DSM 43919
BGC0001660.1	0.17	RiPP	mathermycin	Marinactinospora thermotolerans
BGC0001258.1	0.17	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0000626.1	0.17	RiPP	thuricin	Bacillus thuringiensis
BGC0000616.1	0.17	RiPP	amylocyclicin	Bacillus velezensis FZB42
BGC0000539.1	0.16	RiPP	nukacin ISK-1	Staphylococcus warneri
BGC0001779.1	0.16	RiPP	siamycin	Streptomyces nodosus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000044.1	0.49	Polyketide	dawenol	Stigmatella aurantiaca DW4/3-1
BGC0000410.1	0.49	NRP	pseudomonine	Pseudomonas fluorescens
BGC0001579.1	0.48	RiPP	duramycin	Streptomyces cinnamoneus
BGC0001364.1	0.48	RiPP	cinnamycin B	Actinomadura atramentaria DSM 43919
BGC0001660.1	0.48	RiPP	mathermycin	Marinactinospora thermotolerans
BGC0001258.1	0.48	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0000626.1	0.48	RiPP	thuricin	Bacillus thuringiensis
BGC0000616.1	0.48	RiPP	amylocyclicin	Bacillus velezensis FZB42
BGC0000539.1	0.47	RiPP	nukacin ISK-1	Staphylococcus warneri
BGC0001779.1	0.47	RiPP	siamycin	Streptomyces nodosus

Similar known gene clusters

No matches found.

Module view

Legend

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 3, location 1848496 - 1890977:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_1829

PKS_AT (30..321): mal

ATSignature: (unknown)

No matches above 50%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 27.5
Methoxymalonyl-CoA: 21.9
Methylmalonyl-CoA: 18.4
trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0