GCF_000285555.1_ASM28555v1_genomic - 3 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_HE610996.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	NRPS,betalactone	14,831	61,640	bacillibactin	NRP:NRP siderophore	60%
Region 1.2	terpene	94,395	115,222

NZ_HE610999.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 4.1	betalactone	259,004	283,098	fengycin	NRP	46%

No secondary metabolite regions were found in these records:: NZ_HE610997.1; NZ_HE610998.1; NZ_HE611000.1; NZ_HE611001.1; NZ_HE611002.1; NZ_HE611003.1; NZ_HE611004.1; NZ_HE611005.1; NZ_HE611006.1; NZ_HE611007.1; NZ_HE611008.1; NZ_HE611009.1; NZ_HE611010.1; NZ_HE611011.1; NZ_HE611012.1; NZ_HE611013.1; NZ_CAEU01000072 (original name was: NZ_CAEU01000072.1)

Compact view

NZ_HE610996.1 - Region 1 - NRPS,betalactone

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Location: 14,831 - 61,640 nt. (total: 46,810 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))
betalactone: (HMGL-like and AMP-binding)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001615.1	0.65	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0000457.1	0.61	NRP	vicibactin	Rhizobium etli CFN 42
BGC0001149.1	0.53	NRP, Saccharide	brabantamide A	Pseudomonas sp. SHC52
BGC0001132.1	0.53	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001833.1	0.53	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001825.1	0.53	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0000321.1	0.52	NRP	chaetocin	Collariella virescens
BGC0001185.1	0.52	NRP	bacillibactin	Bacillus velezensis FZB42
BGC0001131.1	0.51	NRP	ambactin	Xenorhabdus miraniensis
BGC0001873.1	0.50	NRP	pyrrolizixenamide A	Xenorhabdus szentirmaii DSM 16338

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001615.1	0.66	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0000457.1	0.64	NRP	vicibactin	Rhizobium etli CFN 42
BGC0001149.1	0.60	NRP, Saccharide	brabantamide A	Pseudomonas sp. SHC52
BGC0001132.1	0.60	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001833.1	0.60	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001825.1	0.60	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0000321.1	0.60	NRP	chaetocin	Collariella virescens
BGC0001185.1	0.59	NRP	bacillibactin	Bacillus velezensis FZB42
BGC0000410.1	0.59	NRP	pseudomonine	Pseudomonas fluorescens
BGC0001585.1	0.59	Alkaloid	melinacidin IV	Escovopsis weberi

Similar known gene clusters

Module view

Legend

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 14830 - 61640:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly - thr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_42

Search NORINE for peptide: strict or relaxed

AMP-binding (432..815): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGMIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

AMP-binding (1435..1830): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

ctg1_44

Search NORINE for peptide: strict or relaxed

AMP-binding (31..435): dhb

NRPSPredictor2: dhb

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: dhb, sal
Small clusters prediction:: dhb, sal
Single AA prediction:: dhb

Stachelhaus prediction details:

Stachelhaus sequence:: PMPAlGVVNK
Nearest Stachelhaus code:: dhb
Stachelhaus code match:: 90% (moderate)

NZ_HE610996.1 - Region 2 - terpene

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Location: 94,395 - 115,222 nt. (total: 20,828 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000851.1	0.19	Other	albonoursin	Streptomyces noursei ATCC 11455
BGC0000452.1	0.06	NRP	tyrocidine	Brevibacillus brevis NBRC 100599
BGC0000727.1	0.06	Saccharide	indigoidine	Streptomyces aureofaciens
BGC0001215.1	0.05	NRP	conglobatin	Streptomyces conglobatus
BGC0001022.1	0.04	NRP, Polyketide	myxalamid	Stigmatella aurantiaca
BGC0000100.1	0.04	Polyketide	monensin	Streptomyces cinnamonensis
BGC0001580.1	0.04	Polyketide	ebelactone	Kitasatospora aburaviensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000851.1	0.52	Other	albonoursin	Streptomyces noursei ATCC 11455
BGC0000452.1	0.26	NRP	tyrocidine	Brevibacillus brevis NBRC 100599
BGC0000727.1	0.24	Saccharide	indigoidine	Streptomyces aureofaciens
BGC0001215.1	0.22	NRP	conglobatin	Streptomyces conglobatus
BGC0001022.1	0.19	NRP, Polyketide	myxalamid	Stigmatella aurantiaca
BGC0000100.1	0.18	Polyketide	monensin	Streptomyces cinnamonensis
BGC0001580.1	0.18	Polyketide	ebelactone	Kitasatospora aburaviensis

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NZ_HE610999.1 - Region 1 - betalactone

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Location: 259,004 - 283,098 nt. (total: 24,095 nt) Show pHMM detection rules used

betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001778.1	0.29	Other	showdomycin	Streptomyces showdoensis
BGC0000234.1	0.21	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0001897.1	0.21	Polyketide	cepacin A	Burkholderia ambifaria IOP40-10
BGC0000842.1	0.19	Other (Non-NRP beta-lactam)	carbapenem MM4550	Streptomyces argenteolus
BGC0000258.1	0.19	Polyketide	prodigiosin	Serratia sp.
BGC0002034.1	0.16	Other	perquinoline A, perquinoline B, perquinoline C	Streptomyces sp. IB2014 016-6
BGC0000522.1	0.16	RiPP	lacticin Z	Lactococcus lactis
BGC0001343.1	0.16	Polyketide	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0000620.1	0.16	RiPP	lacticin Q	Lactococcus lactis
BGC0000634.1	0.16	Terpene	carotenoid	Brevundimonas sp. SD212

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001778.1	0.63	Other	showdomycin	Streptomyces showdoensis
BGC0000234.1	0.54	Polyketide	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0001897.1	0.53	Polyketide	cepacin A	Burkholderia ambifaria IOP40-10
BGC0000842.1	0.52	Other (Non-NRP beta-lactam)	carbapenem MM4550	Streptomyces argenteolus
BGC0000258.1	0.51	Polyketide	prodigiosin	Serratia sp.
BGC0002034.1	0.47	Other	perquinoline A, perquinoline B, perquinoline C	Streptomyces sp. IB2014 016-6
BGC0000522.1	0.47	RiPP	lacticin Z	Lactococcus lactis
BGC0001343.1	0.47	Polyketide	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0000620.1	0.47	RiPP	lacticin Q	Lactococcus lactis
BGC0000634.1	0.47	Terpene	carotenoid	Brevundimonas sp. SD212

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names