GCF_000285835.1_ASM28583v2_genomic - 6 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_HE978602.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 3.1	RiPP-like	171,867	182,670
Region 3.2	terpene	240,412	261,413	carotenoid	Terpene	33%

NZ_HE978603.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 4.1	betalactone	73,585	104,971
Region 4.2	terpene	268,047	288,961

NZ_HE978605.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 6.1	ectoine	121,373	131,777	ectoine	Other	75%

NZ_HE978607.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 8.1	NAPAA	81,751	120,703	ulleungmycin	NRP	5%

Region	Type	From	To	Most similar known cluster	Similarity
Region 3.1	RiPP-like	171,867	182,670
Region 3.2	terpene	240,412	261,413	carotenoid	Terpene	33%
Region 4.1	betalactone	73,585	104,971
Region 4.2	terpene	268,047	288,961
Region 6.1	ectoine	121,373	131,777	ectoine	Other	75%
Region 8.1	NAPAA	81,751	120,703	ulleungmycin	NRP	5%

No secondary metabolite regions were found in these records:: NZ_HE978600.1; NZ_HE978601.1; NZ_HE978604.1; NZ_HE978606.1; NZ_HE978608.1; NZ_HE978609.1; NZ_HE978610.1; NZ_HE978611.1; NZ_HE978612.1; NZ_HE978613.1; NZ_HE978614.1; NZ_HE978615.1; NZ_CAHK01000065 (original name was: NZ_CAHK01000065.1)

Compact view

NZ_HE978602.1 - Region 1 - RiPP-like

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Location: 171,867 - 182,670 nt. (total: 10,804 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001521.1	0.15	NRP	auriculamide	Herpetosiphon aurantiacus DSM 785
BGC0000019.1	0.15	Polyketide	angolamycin	Streptomyces eurythermus
BGC0000703.1	0.14	Saccharide	kanamycin	Streptomyces kanamyceticus
BGC0000698.1	0.14	Saccharide	hygromycin A	Streptomyces hygroscopicus
BGC0001138.1	0.14	Other (Nucleoside)	a201a	Marinactinospora thermotolerans
BGC0001607.1	0.14	Other	gilvusmycin	Streptomyces sp. NRRL B-1347
BGC0001484.1	0.14	Other	2'-chloropentostatin, 2'-amino-2'-deoxyadenosine	Actinomadura sp. ATCC 39365
BGC0001488.1	0.13	Other	4-formylaminooxyvinylglycine	Pseudomonas fluorescens WH6
BGC0000882.1	0.13	Other	mildiomycin	Streptomyces rimofaciens
BGC0000801.1	0.13	Saccharide	galactoglucan	Sinorhizobium meliloti

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001521.1	0.45	NRP	auriculamide	Herpetosiphon aurantiacus DSM 785
BGC0000019.1	0.45	Polyketide	angolamycin	Streptomyces eurythermus
BGC0000703.1	0.44	Saccharide	kanamycin	Streptomyces kanamyceticus
BGC0000698.1	0.44	Saccharide	hygromycin A	Streptomyces hygroscopicus
BGC0001138.1	0.43	Other (Nucleoside)	a201a	Marinactinospora thermotolerans
BGC0001607.1	0.43	Other	gilvusmycin	Streptomyces sp. NRRL B-1347
BGC0001484.1	0.43	Other	2'-chloropentostatin, 2'-amino-2'-deoxyadenosine	Actinomadura sp. ATCC 39365
BGC0001488.1	0.42	Other	4-formylaminooxyvinylglycine	Pseudomonas fluorescens WH6
BGC0000882.1	0.42	Other	mildiomycin	Streptomyces rimofaciens
BGC0000801.1	0.42	Saccharide	galactoglucan	Sinorhizobium meliloti

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NZ_HE978602.1 - Region 2 - terpene

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Location: 240,412 - 261,413 nt. (total: 21,002 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000648.1	0.32	Terpene	carotenoid	Myxococcus xanthus
BGC0000644.1	0.30	Terpene	carotenoid	Dietzia sp. CQ4
BGC0000637.1	0.28	Terpene	carotenoid	Corynebacterium glutamicum
BGC0000650.1	0.25	Terpene	carotenoid	Algoriphagus sp. KK10202C
BGC0001227.1	0.21	Terpene	isorenieratene	Streptomyces collinus Tu 365
BGC0000640.1	0.19	Terpene	carotenoid	Enterobacteriaceae bacterium DC404
BGC0001456.1	0.18	Terpene	isorenieratene	Streptomyces argillaceus
BGC0000664.1	0.18	Terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000636.1	0.18	Terpene	carotenoid	Brevibacterium linens
BGC0000886.1	0.18	Other	allylmalonyl-CoA	Streptomyces tsukubensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000648.1	0.65	Terpene	carotenoid	Myxococcus xanthus
BGC0000644.1	0.64	Terpene	carotenoid	Dietzia sp. CQ4
BGC0000637.1	0.62	Terpene	carotenoid	Corynebacterium glutamicum
BGC0000650.1	0.58	Terpene	carotenoid	Algoriphagus sp. KK10202C
BGC0001227.1	0.54	Terpene	isorenieratene	Streptomyces collinus Tu 365
BGC0000640.1	0.51	Terpene	carotenoid	Enterobacteriaceae bacterium DC404
BGC0001456.1	0.50	Terpene	isorenieratene	Streptomyces argillaceus
BGC0000664.1	0.50	Terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000636.1	0.50	Terpene	carotenoid	Brevibacterium linens
BGC0000886.1	0.50	Other	allylmalonyl-CoA	Streptomyces tsukubensis

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NZ_HE978603.1 - Region 1 - betalactone

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Location: 73,585 - 104,971 nt. (total: 31,387 nt) Show pHMM detection rules used

betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000666.1	0.28	Terpene	xiamycin A	Streptomyces sp. SCSIO 02999
BGC0000665.1	0.28	Terpene, Alkaloid	xiamycin	Streptomyces sp. HKI0576
BGC0001156.1	0.28	Terpene	platencin	Streptomyces platensis
BGC0001140.1	0.28	Terpene	platensimycin, platencin	Streptomyces platensis
BGC0000904.1	0.25	Other	FR-900098	Streptomyces rubellomurinus
BGC0000663.1	0.20	Terpene	hopene	Streptomyces coelicolor A3(2)
BGC0000258.1	0.18	Polyketide	prodigiosin	Serratia sp.
BGC0000259.1	0.18	Polyketide	prodigiosin	Serratia marcescens
BGC0000260.1	0.15	Polyketide	prodigiosin	Hahella chejuensis KCTC 2396
BGC0002036.1	0.15	Other	dehydrofosmidomycin	Streptomyces lavendulae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000666.1	0.62	Terpene	xiamycin A	Streptomyces sp. SCSIO 02999
BGC0000665.1	0.62	Terpene, Alkaloid	xiamycin	Streptomyces sp. HKI0576
BGC0001156.1	0.61	Terpene	platencin	Streptomyces platensis
BGC0001140.1	0.61	Terpene	platensimycin, platencin	Streptomyces platensis
BGC0000904.1	0.58	Other	FR-900098	Streptomyces rubellomurinus
BGC0000663.1	0.52	Terpene	hopene	Streptomyces coelicolor A3(2)
BGC0000258.1	0.50	Polyketide	prodigiosin	Serratia sp.
BGC0000259.1	0.49	Polyketide	prodigiosin	Serratia marcescens
BGC0000260.1	0.45	Polyketide	prodigiosin	Hahella chejuensis KCTC 2396
BGC0002036.1	0.45	Other	dehydrofosmidomycin	Streptomyces lavendulae

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NZ_HE978603.1 - Region 2 - terpene

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Location: 268,047 - 288,961 nt. (total: 20,915 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000650.1	0.33	Terpene	carotenoid	Algoriphagus sp. KK10202C
BGC0000596.1	0.18	RiPP	SLI-2138	Streptomyces lividans TK24
BGC0000595.1	0.18	RiPP	SCO-2138	Streptomyces coelicolor A3(2)
BGC0000633.1	0.17	Terpene	carotenoid	Streptomyces avermitilis
BGC0001456.1	0.17	Terpene	isorenieratene	Streptomyces argillaceus
BGC0001150.1	0.17	Polyketide	pamamycin-607	Streptomyces alboniger
BGC0000644.1	0.16	Terpene	carotenoid	Dietzia sp. CQ4
BGC0000637.1	0.16	Terpene	carotenoid	Corynebacterium glutamicum
BGC0000243.1	0.15	Polyketide	macrotetrolide	Streptomyces griseus subsp. griseus
BGC0000906.1	0.14	Other	heme D1	Heliophilum fasciatum

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000650.1	0.66	Terpene	carotenoid	Algoriphagus sp. KK10202C
BGC0000596.1	0.50	RiPP	SLI-2138	Streptomyces lividans TK24
BGC0000595.1	0.50	RiPP	SCO-2138	Streptomyces coelicolor A3(2)
BGC0000633.1	0.49	Terpene	carotenoid	Streptomyces avermitilis
BGC0001456.1	0.48	Terpene	isorenieratene	Streptomyces argillaceus
BGC0001150.1	0.48	Polyketide	pamamycin-607	Streptomyces alboniger
BGC0000644.1	0.47	Terpene	carotenoid	Dietzia sp. CQ4
BGC0000637.1	0.46	Terpene	carotenoid	Corynebacterium glutamicum
BGC0000243.1	0.45	Polyketide	macrotetrolide	Streptomyces griseus subsp. griseus
BGC0000906.1	0.43	Other	heme D1	Heliophilum fasciatum

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

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NZ_HE978605.1 - Region 1 - ectoine

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Location: 121,373 - 131,777 nt. (total: 10,405 nt) Show pHMM detection rules used

ectoine: ectoine_synt

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000853.1	0.42	Other	ectoine	Streptomyces anulatus
BGC0000855.1	0.40	Other	ectoine	Methylomicrobium kenyense
BGC0000859.1	0.40	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000856.1	0.40	Other	ectoine	Methylophaga thalassica
BGC0000858.1	0.39	Other	ectoine	Methylobacter marinus
BGC0000852.1	0.38	Other	ectoine	Sporosarcina pasteurii
BGC0000860.1	0.31	Other	ectoine	Methylarcula marina
BGC0000857.1	0.30	Other	ectoine	Methylophaga alcalica
BGC0000854.1	0.28	Other	ectoine	Methylomicrobium alcaliphilum 20Z
BGC0000665.1	0.15	Terpene, Alkaloid	xiamycin	Streptomyces sp. HKI0576

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000853.1	0.74	Other	ectoine	Streptomyces anulatus
BGC0000855.1	0.72	Other	ectoine	Methylomicrobium kenyense
BGC0000859.1	0.72	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000856.1	0.72	Other	ectoine	Methylophaga thalassica
BGC0000858.1	0.71	Other	ectoine	Methylobacter marinus
BGC0000852.1	0.71	Other	ectoine	Sporosarcina pasteurii
BGC0000860.1	0.64	Other	ectoine	Methylarcula marina
BGC0000857.1	0.64	Other	ectoine	Methylophaga alcalica
BGC0000854.1	0.62	Other	ectoine	Methylomicrobium alcaliphilum 20Z
BGC0000665.1	0.45	Terpene, Alkaloid	xiamycin	Streptomyces sp. HKI0576

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NZ_HE978607.1 - Region 1 - NAPAA

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Location: 81,751 - 120,703 nt. (total: 38,953 nt) Show pHMM detection rules used

NAPAA: (AMP-binding and PP-binding and TIGR02353)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001302.1	0.27	Other	lomofungin	Streptomyces lomondensis
BGC0002008.1	0.24	Other	aryl polyenes	Xenorhabdus doucetiae
BGC0000836.1	0.24	Other	APE Ec	Escherichia coli CFT073
BGC0000837.1	0.23	Other	APE Vf	Aliivibrio fischeri ES114
BGC0000551.1	0.22	RiPP	SapB	Streptomyces coelicolor A3(2)
BGC0001050.1	0.22	NRP, Polyketide	thalassospiramide A	Tistrella bauzanensis
BGC0000258.1	0.22	Polyketide	prodigiosin	Serratia sp.
BGC0000513.1	0.22	RiPP	Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3	Saccharopolyspora erythraea NRRL 2338
BGC0001483.1	0.22	Other	5-isoprenylindole-3-carboxylate β-D-glycosyl ester	Streptomyces sp. RM-5-8
BGC0000678.1	0.22	Terpene	pentalenolactone	Streptomyces avermitilis MA-4680 = NBRC 14893

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001302.1	0.61	Other	lomofungin	Streptomyces lomondensis
BGC0002008.1	0.58	Other	aryl polyenes	Xenorhabdus doucetiae
BGC0000836.1	0.58	Other	APE Ec	Escherichia coli CFT073
BGC0000837.1	0.56	Other	APE Vf	Aliivibrio fischeri ES114
BGC0000551.1	0.55	RiPP	SapB	Streptomyces coelicolor A3(2)
BGC0001050.1	0.55	NRP, Polyketide	thalassospiramide A	Tistrella bauzanensis
BGC0000258.1	0.55	Polyketide	prodigiosin	Serratia sp.
BGC0000513.1	0.55	RiPP	Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3	Saccharopolyspora erythraea NRRL 2338
BGC0001483.1	0.55	Other	5-isoprenylindole-3-carboxylate β-D-glycosyl ester	Streptomyces sp. RM-5-8
BGC0000678.1	0.54	Terpene	pentalenolactone	Streptomyces avermitilis MA-4680 = NBRC 14893

Similar known gene clusters

Module view

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Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 81750 - 120703:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg8_83

Search NORINE for peptide: strict or relaxed

AMP-binding (47..422): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAESIGtVvK
Nearest Stachelhaus code:: lys
Stachelhaus code match:: 80% (moderate)

ctg8_87

Search NORINE for peptide: strict or relaxed

AMP-binding (42..460): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: glu, gln
Single AA prediction:: gln

Stachelhaus prediction details:

Stachelhaus sequence:: itcaMGGaqK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 40% (weak)

ctg8_94

Search NORINE for peptide: strict or relaxed

AMP-binding (17..414): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: gLTssGgavK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 40% (weak)