LOCUS       c00020_NZ_FOJI..       14071 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_FOJI01000014.1 [Clostridium] fimetarium strain DSM 9179, whole
            genome shotgun sequence.
ACCESSION   NZ_FOJI01000014
VERSION     NZ_FOJI01000014
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:16:02
            Original ID  :: NZ_FOJI01000014.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14071
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14071
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[538:4071]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      539..4071
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..14071
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14071
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             complement(539..1699)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_1"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 8.5e-13,
                     bitscore: 41.2, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPNQIDFSQIKTPAYIVDERLLERNLQLLKNIMDRTDCKILLAQK
                     GFSMFSLYPMIGKYLIGTTASSLYEAKLGKEEMGGETHIFAPAYREEEFSEILSLCDHI
                     VFNSLKQWIYFREKVQQADQNGKKHTCGIRINPEYAEVEHEIYNPCCEGSRLGTTLLDF
                     QEALEENPDALNGIDGLHFHVMCEQNSDTLERVLDHVEEKFGKYMYQMKWINFGGGHHI
                     TRADYDIELLVKCINRVQNKYDVAVYLEPGEAVALNTGYLIASVMDIKGNAAIIDASAA
                     CHMPDVLEMPYRPEIIDAGKPNEKKYTYKLGGNTCLAGDIVGEYSFDKPLMPGDKLVFC
                     DMAHYSMVKNNTFNGIRLPSILSYNDIEGIKIIKEFGYEDFKERLS"
     CDS             complement(1895..3094)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_2"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 1.4e-40, bitscore:
                     132.8, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 1.3e-37,
                     bitscore: 121.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGRALIIGAGGVAGVVVHKCCQNSEVFEEICIASRTKSKCDALKE
                     KLDGGKTQITTAQVDADNVSELVQLINSYKPDIVMNIALPYQDLTIMDACLETKTNYMD
                     TANYEPLDTAKFEYKWQWVYKEKFEKAGITALLGSGFDPGVTGVFSAYAAKHYFDEISE
                     IDILDCNGGEHGYPFATNFNPEINIREVSAKGSYWEYGKWIETEPMEIKRTYNFDEVGE
                     KDMYLLHHEELESLAINIKGIKRIRFFMTFGQSYLTHLKCLENVGMTSIIPIEYEGKQI
                     VPLQFLKAVLPDPASLGPRTKGKTNIGCIFTGKKDGKEKTYYVYNVCDHQECYKEVGSQ
                     AISYTTGVPAMIGAMMVMTGKWDAPGVYNIEEFDPDPFMEALNKWGLPWKENFRPVLVD
                     "
     CDS             complement(3211..4071)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_3"
                     /sec_met_domain="Spermine_synth (E-value: 3.1e-54,
                     bitscore: 175.9, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 2.1e-15,
                     bitscore: 49.2, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKNMELWYTDQHTKDVRFSMKIEEQIASCESEFQRIDILKSCEFG
                     KVLVLDGELMITQKDEFIYHEMISHVPMAVHPNVKNVLVIGAGDGGTIRELTKYDTIER
                     IDMVEIDKMVTDMCLEHFQETSCKLNDKRVHMYFEESLRYVRMKNDEYDLIIVDCADPY
                     GPAEGLFTREFYGNCFKALHDDGILINQHESPYYSEHSRTVQKAHNHIKLVFPFSTVYQ
                     CHIPSYPSGHWLFGFASKKYDPINDLNEEAWNKLGIKTRYYNTDLHKGSFYLPTYVKEL
                     LGTNE"
     CDS             complement(4088..5548)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_4"
                     /sec_met_domain="OKR_DC_1_C (E-value: 6.3e-12, bitscore:
                     38.7, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 1.7e-130,
                     bitscore: 427.9, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKTELTQYDTPIHRALEEQRLNRLAHFDVPGHKGGRGNKELREFL
                     GAECMKLDMNSMKPLDNLCHPVSVIKDAQELAAQAFGADEAFFIVNGTTAAVQAMIMST
                     TEAGDKIIMPRNVHRSAINALVVNGAIPVYINPGVNKKLGIPLGMSVESVKQSIRENPD
                     ARAILVNNPTYYGICSDLKAIVELAHESGMLVLVDEAHGTHFYFNDRMPISAMAAGADM
                     SAVSMHKTGGSLTQSSILLTKNTVNADYVRQVINLTQTTSGSYLLLSSLDIARKNMSLN
                     GQVLIDKAIEFATYAREEINKLGGYYAFGEELIDGDMIYDFDTTKLSVHTRDIGLAGIE
                     VYDFLRDEFGIQIEFGDIGNILAIISGGDRNLEIERLISALSEVKRLHEKDKSGMFDHE
                     YITPVVVMGPQKAFYSYKVSLPIQESDGKICGEFVMCYPPGIPILAPGEMITKEIIKYI
                     EYAREKGCILTGTQDMNVENINVVDTAI"
     CDS             complement(5604..6371)
                     /locus_tag="ctg20_5"
                     /transl_table=11
                     /translation="MNWVLVGVIVVLGLNAYFGLKKGMVRIILSLAAMIATILITMALT
                     PIASSFIKDNTNWYTNIKNATYQTMQRNNTVDDAFQEMGKTQDITKITDINQSSTSMQN
                     VSSQVIDKLKVPESLKNQIQSKINIEKYVGQGITTVEDMVANALAEQVSLIIFNILVFA
                     GIFIVVYIIMQVIIRVVDIVSRLPVLKQINKTGGLVLGLAKGLIVVWVFFIAITIFCDT
                     EFAHTVFAYVNSNSFLAFLYNNNLILKLIFAII"
     CDS             complement(6394..7704)
                     /locus_tag="ctg20_6"
                     /transl_table=11
                     /translation="VADIKHYLQIKKNIENKKAKNPNPSNSSNVVKGVFKDYNNSFNGR
                     DDDDDDDDDDDGLHKKIHNHRIKIAIIIGICVIAFIAIAVIVAVSLDNIKYSGYTIIKS
                     ISKDDTEAAQYIDYNNGYIRYSNDGISCYTNKGEAIWNQTYQMKAPQVKICGKSLAIGD
                     LNGSSIYIFNDKGFLYNVDTSLPISQIEVSIQGLAAAVLEDTNVNYIRLYNTDGSILYT
                     VKTELAQNGYPLDISMSDDATKLVASYVLVNGDSIKTNVVFYSFSDVGENETEKVVGGF
                     NQYDSTLVPKVKFINDTCAVAIGENVLSIYKIKEYPTLLKDIKVDSEIERVFMSDVYIG
                     LVLKNSDAGDVYKMLVYNINGTQAFETTFNTEYNIIKFDGKSIIMYNDTTFTLMNINGK
                     IQFEQSFDLPIKSILSLGSKGDYMLINSKYIQEIKLK"
     CDS             complement(7760..8902)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_7"
                     /sec_met_domain="LysM (E-value: 3.6e-14, bitscore: 45.4,
                     seeds: 155, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEIVCNDGEKKSLNEQQNIKRPKNIKQIGDMHSNKKIYIEDYVF
                     TYINSIAYEDSDKLRVGVLLGESKKSGGESYVFIKGAVKIEIDEDENRITFSENVWSLI
                     YEDMEKYFHNLEITGWFVTTPDVTLDFMSNLEKIHLDNFAGNMKALYLVNTSEKEEDFY
                     FYEGKCLKKQSGYVCFYERNNDMQEYMLAKRTGKSVDPMVEDDVIHNFRTIIAEKKEVA
                     EQKKTMSLMYGISTFMIVVVLVIGINMMNSYEKMRGLDVTLNQIVQQVANMNVKSTTSI
                     DDETTSTTVKKIVGGVYPTEAQTQVSATVAATQAQTQAPTSSTPVDVKPVASYIVQKGD
                     TLMSICRKIYGDSLRYKEIMEINKIDDPDKIFIGQEIKLP"
     CDS             9198..9728
                     /locus_tag="ctg20_8"
                     /transl_table=11
                     /translation="MLFYYNSDLSETPREMSSQISKFVHPEIIGNRQVIVLCIGSDRST
                     GDSLGPLIGYKLIKSGLTNVTIYGSLKNPVHATNLNATIDEIYNLYNNPYVIAIDASLG
                     KKDHIGCITLGTGALKPGLGVKKQLPEVGDIHITGIVNLSGAMDTLLLQTTRLSTIMTL
                     ADVISEALINSLN"
     CDS             complement(9800..10894)
                     /locus_tag="ctg20_9"
                     /transl_table=11
                     /translation="MEEQNILTCDIICLNQIKSDIKEHNIAKEKIEPVKVAVKDLEKNI
                     ESLEKAVRDEIESTLKTRREAVASGFDKEIESDQEKLKKIQSDRDKAKSKGVKERISVE
                     TSSLREDNKGMKDEIKAAFKSNRIPRFCNSRLFLALFMTKGFKDAFICIVTFLITFLAV
                     PSAIYYFVPNMPDWSLILIYIVLVAIVFTIYKLISEKIKFPHLEVIQGLIKTKDRITEN
                     KRKIRKIVHAIKKDKNEEMYGLDKFDEKINIIITDIEKFEAKKSLALEDFNNLVKPNII
                     AEIEGKDKERIIALKVDLEKKHSLLTEMEDKVKEQRIYIASNYEAYLGNEFATPDKLEA
                     LAEIMNTGGAETIGKAIAVYKTKK"
     CDS             complement(10923..13217)
                     /locus_tag="ctg20_10"
                     /transl_table=11
                     /translation="MIQLSKGGAYLINGNEVIEDGADIAAILKSKLGENVPSKKEAAKN
                     TLAYEILEKHNTSGSMDKLKVKFDKLTSHDITFVGIIQTARASGLEKFPIPYVLTNCHN
                     SLCAVGGTINEDDHMFGLTCAKKYGGIYVPPHQAVIHQFAREMLAGGGKMILGSDSHTR
                     YGALGTMAMGEGGPELVKQLLDKTYDINMPGVVGVYMTGEPMKGVGPQDVALAIIGEVF
                     GNGYVKNKVMEFVGPGISNLSADFRIGIDVMTTETTCLSSIWKTDDKIKEFYDIHGRSA
                     DFKELNPGNVTYYDGMIYVNLSEIKPMIAMPFHPSNTYTIEELNANLLDILDECEKKAL
                     VSLGGQVEYSLKDKVRNGKLYVEQGIIAGCAGGGFENICAAADILRNKSIGNDEFTLSV
                     YPASTPIYMELARNGDLADLLGTGAIVKTAFCGPCFGAGDTPANNAFSIRHSTRNFPNR
                     EGSKLQNGQISSVALMDARSIAATAANKGFLTSATDIDVEYKNPKYFFDKSIYENRVFD
                     SKGIPDPDVEIQFGPNIKDWPEMSALTDNLVLKVVAEIHDPVTTTDELIPSGETSSYRS
                     NPLGLAEYTLSRKDPGYVGRAKEVHVAEKARIAGESPEEAFPEIKSIMDKIKASYPDIN
                     NTNIGIGSAIFAVKPGDGSAREQAASCQKVLGGWANIANDYATKRYRSNLINWGMLPFL
                     VKAGELPFKKGDYLFVPGIKEAVKNKNDSIRAFVVGDTLKEFELKLGELTDDERKIILE
                     GCLINFYRENN"
     CDS             complement(13358..13777)
                     /locus_tag="ctg20_11"
                     /transl_table=11
                     /translation="MRKDDCIFCRLANGDIPTNALYEDDIVKAIFDLSPASMGHIIILP
                     KEHFDNLYSIDEETAAHVFKVATRLAKAIKEALNCDGMNILQNNGEIAGQTVFHFHMHI
                     IPRYLGDNVKFSWNQGKISEDEIKDLKKKIQNRFK"
ORIGIN
        1 accgttcgtt tattttgaaa ttcttttata gaattttcaa ggttgtttta ctatttagtt
       61 atcaatgttc aattcaaact ttttcttggg ttcgtatacc gaataatcca gtatttatgc
      121 gccttcgagt attgtttgtg tgttgccatg tgttacagcg acttggttat cttatcattc
      181 tgagcccact ttgtcaacac tatttttcgc cttttttatt ctttttattt tttctttgat
      241 ttgtcagctg cattttacat attttagatt taaaaaaaga gtaataattt gtatccaaaa
      301 tttcttataa ggtagatgtt tattgggtaa acagtatatt acctgacttc ataacacctt
      361 tcaaaatggt ctatttattg aatgctataa acttaagtct gtatatctta ttccacaatt
      421 ttccactcat ccaaattcat attaatcgcc agtttataca gactccccca agtgatcggt
      481 ttctgaaaac tgcattttca tttctaccag cattatagtt taacaattat ctcataattt
      541 atgacagtct ttccttaaaa tcttcataac caaattcctt tataatctta attccttcta
      601 tatcattata agaaagaatt gacggtaatc taatcccatt aaatgtattg ttttttacca
      661 tgctataatg tgccatatca caaaatacga gcttatcacc cggcattaat ggcttgtcaa
      721 atgagtattc gcctactata tctcctgcaa ggcaagtatt tccaccaagc ttataagtgt
      781 acttcttttc gtttggcttg cctgcatcaa ttatttccgg acgatatggc atttcaagca
      841 catctggcat atggcatgct gcagacgcat ctattattgc agcgttccct tttatatcca
      901 ttactgatgc tattaaatat ccggtgttta gcgctaccgc ttcccctggc tctagatata
      961 ctgcaacatc atatttattc tgtactctat taatacattt tacaagtagt tctatgtcgt
     1021 aatccgctct tgtaatatga tgtcctccgc caaaattaat ccatttcatc tgatacatgt
     1081 atttaccgaa tttttcttct acatgatcta acactctttc taatgtatcc gaattctgtt
     1141 cacacattac gtgaaaatgc aaaccatcta ttccatttaa tgcgtctgga ttttcctcta
     1201 gtgcctcttg aaaatctaga agtgttgttc caagtctgga accttcgcaa catggattat
     1261 atatctcatg ttcaacttct gcatattccg ggttgattcg gattccacac gtatgctttt
     1321 tgccattttg atccgcttgt tgcacttttt ctcgaaaata aatccactgt ttaagagaat
     1381 tgaaaacgat gtggtcgcat aatgataaaa tctcagaaaa ttcttcttct ctatatgcag
     1441 gtgcaaatat atgagtctct ccacccatct cttcttttcc aagctttgct tcatataacg
     1501 agcttgctgt tgttccaatt aagtattttc ctatcatagg atataaagaa aacattgaaa
     1561 atcctttttg agccaacaat attttgcaat cagttctatc cattatattt ttaagtaatt
     1621 gcaaatttct ttcaagcaat ctctcatcta caatatatgc aggtgtttta atttgtgaaa
     1681 aatctatttg attaggcatt gtattcttct ccttagcatt ttatttatta atctaaacca
     1741 ataattagat tcagtattac ttataataat tttccaataa acttaattgt ttgtcaagga
     1801 acattattta tagtatattt tgtttaaaaa tgctcctcct tatggttgac agttttattg
     1861 ttttaactgt ctaccacaag gggagcacct atatttaatc gactaatacc ggtctaaagt
     1921 tctctttcca tggaagtccc catttattga gtgcctccat aaatggatct ggatcaaatt
     1981 cttcaatgtt atatacacct ggtgcatccc attttccagt catcaccatc atagcaccaa
     2041 tcattgctgg cacgcctgtt gtatatgaaa tcgcctgtga gccgacttct ttatagcatt
     2101 cctggtgatc acatacattg tatacataat atgtcttttc cttaccatct ttctttcctg
     2161 tgaaaataca tccgatattg gttttgcctt tcgttcttgg accaagtgac gctggatctg
     2221 gaagaactgc ctttaaaaat tgaagcggaa ctatctgttt tccctcatat tcaattggta
     2281 tgattgatgt cattcctaca ttttcaagac attttaaatg tgtaagatag ctttgtccaa
     2341 atgtcataaa gaaacggatt ctcttaatac ccttaatatt aatggcaagc gattctaatt
     2401 cttcatggtg aagaagatac atgtcttttt cgccaacttc atcaaagtta tatgttcttt
     2461 taatctccat tggttctgtt tcaatccatt taccatattc ccagtagcta ccttttgcag
     2521 aaacttcacg aatgtttatt tctggattaa aattagttgc aaatggatag ccatgttcgc
     2581 caccattaca gtccaaaata tctatttcac ttatctcgtc gaaataatgt tttgcagcat
     2641 acgctgaaaa tacaccagtt acacctgggt caaatcctga tccaagaagt gctgtgattc
     2701 cagctttttc aaacttttcc ttatataccc actgccattt gtactcgaat tttgcagtat
     2761 caagtggctc ataattagcc gtatccatat agttggtctt tgtttcaaga caagcgtcca
     2821 taattgtaag atcttgatat ggaagcgcaa tattcattac gatatctggt ttgtaactat
     2881 taattaattg aacaagttct gaaacattat ctgcatctac ttgtgccgtt gtgatttgtg
     2941 tttttccacc atcaagtttt tcctttaaag catcacattt tgatttggtg cggcttgcta
     3001 tacatatttc ttcaaatacc tctgaatttt gacaacattt atgaaccact acaccagcaa
     3061 ctccgccagc gcctattatt aaagctcttc ccacttaatt tcctccgttt cttaatgttc
     3121 ttttatttta ttattcattc ttttcattac tcattcgttc cattattcat tctttttatt
     3181 attcattctt tttattattc attcttttta ttattcattc gttccaagta gttctttcac
     3241 atatgttggc aaatagaaac tgcctttatg taaatccgta ttataatatc tggtttttat
     3301 tcctaattta ttccatgctt cttcatttaa atcattaatt gggtcatatt tttttgatgc
     3361 aaatccaaac agccaatgtc ccgatggata tgatggaata tgacattgat ataccgtact
     3421 gaaaggaaac actaatttta tatgattatg tgctttttgt acagtcctag aatgctcact
     3481 gtaatatggg ctctcatgtt ggttaatcag tataccatca tcatgaagtg ccttgaaaca
     3541 attaccatag aattctctag taaacaagcc ttctgctggc ccgtatggat ccgcacaatc
     3601 tactattatt aaatcatact catcattttt cattcttaca tatcttaagc tttcctcaaa
     3661 atacatatga actcttttat catttaactt gcatgaggtt tcctgaaaat gttctaagca
     3721 catatccgta accatcttat caatctctac catatcgata cgttctattg tatcgtattt
     3781 tgttaactct ctaatcgttc cgccatcacc agcgccaatt acaagtacat ttttaacatt
     3841 gggatgaact gccattggca catgagatat catttcatgg tatataaatt catccttttg
     3901 agtaatcata agttctccat ctagaacaag aactttacca aactcacatg attttaatat
     3961 atcgattctt tgaaattcac tttcgcaact tgcaatctgt tcttcgattt tcatagaaaa
     4021 gcggacatcc tttgtatgtt ggtctgtata ccaaagttcc atattcttca cctattttcc
     4081 tttcatgcta tattgccgta tctaccacgt taatattttc aacattcata tcttgagtac
     4141 cagtcaaaat acaacctttt tctcttgcat attcgatata tttaataatt tctttcgtta
     4201 tcatctcgcc aggtgcaaga attggaattc caggtggata acacataaca aattctccac
     4261 agatctttcc gtcactttct tgaattggca aagaaacttt ataactataa aatgcttttt
     4321 gtggtcccat aactactact ggagtgatat attcatgatc aaacataccg gatttatcct
     4381 tttcatgaag tcttttaacc tccgaaagtg ctgatataag acgttctatt tctagatttc
     4441 tatcaccacc agaaattatt gcaagtatat ttccgatatc accgaattca atttgaattc
     4501 caaattcatc tcttaagaaa tcataaacct caatccctgc aagaccaata tcgcgtgtat
     4561 gaaccgaaag tttcgttgta tcaaagtcat aaatcatatc gccatcaatt aattcttcac
     4621 caaatgcata atatccacca agtttgttta tttcttctct tgcataagta gcaaattcaa
     4681 tggctttatc aatcagtact tgcccattaa gactcatatt cttccttgct atatcaagtg
     4741 atgataacaa aagatatgat ccacttgtgg tttgcgtaag attgattacc tgacgaacat
     4801 aatcagcatt tacagtattc ttagtaagta aaatcgaact ctgcgtaagt gatcctcctg
     4861 ttttatgcat actgactgca gacatatctg cacctgctgc cattgcagaa ataggcattc
     4921 tgtcattaaa atagaaatgc gtaccgtgtg cttcatctac taaaacaagc attccactct
     4981 catgtgctag ctctactatc gcttttaaat cagaacagat tccataatag gttggattat
     5041 tcacaagaat tgcccttgca tctggattct ctctaattga ctgtttcaca ctttcaactg
     5101 acattcctag cggaataccc agtttcttat tcacgcctgg attaatatat actggaattg
     5161 ctccatttac aaccaatgca ttaattgcgc ttctatgaac attgcgtggc ataattatct
     5221 tgtcaccagc ttctgttgtt gacattatca tggcttgtac tgctgctgtt gttccattta
     5281 cgatgaaaaa agcttcgtct gcgccaaatg cttgtgccgc taactcttgc gcatctttaa
     5341 taaccgaaac aggatgacac aggttgtcaa gcggtttcat tgaattcata tcaagtttca
     5401 tacattctgc accaagaaat tcgcggagtt ctttgtttcc tcttccgcct ttgtggccag
     5461 gcacgtcaaa atgagcaagc ctatttaagc gttgctcttc taaagctctg tgtatcggtg
     5521 tatcatattg tgtcaattct gttttcactt ttgttttaca ctcctttatc ataatcgtat
     5581 cagcaatata ttatttgcag agattaaata atagcaaata taagcttcaa gataaggttg
     5641 ttgttataaa ggaatgctaa aaatgaatta ctattaacat atgcaaatac tgtatgtgca
     5701 aattctgtat cacagaatat tgttattgca ataaaaaata cccaaacaac aattagtcct
     5761 tttgctaagc ctaaaaccaa gcctcctgtt ttgttaatct gtttaagaac tggaagccta
     5821 cttactatat caaccactct aataattacc tgcataataa tatacactac tataaatata
     5881 ccagcaaata ctaatatatt gaaaataatc aaagatactt gttccgctaa agcattcgcc
     5941 accatatctt cgactgttgt gattccttgt cctacatact tctcaatatt tattttagac
     6001 tgtatctgat ttttcaaact ttcaggaacc ttaagtttgt ctatcacttg acttgaaaca
     6061 ttttgcatac ttgtactaga ttgattaata tcagtgattt ttgttatatc ttgtgtttta
     6121 cccatttctt gaaaagcatc atcaacggta ttatttcgtt gcatcgtctg atatgtagca
     6181 tttttaatat ttgtatacca gttcgtatta tccttaataa aactgctagc gattggtgtc
     6241 aatgccattg taatcaaaat ggtagctatc atcgctgcta aagaaagaat aatcctaacc
     6301 attccctttt ttaatccaaa atatgcattc aatccaagta ctactattac gccaactaaa
     6361 acccagttca tactatttcc tccgtttata agtttatttt agttttatct cttgtatata
     6421 ttttgaattt ataagcatat aatcaccctt tgatccaagt gaaagaatgg actttatagg
     6481 taaatcaaaa gactgttcga attgtatttt cccgtttata ttcattaatg taaacgttgt
     6541 atcattatac attattatac tttttccatc aaacttaatt atattatatt cagtattaaa
     6601 tgttgtctca aatgcttgag ttccatttat attataaact agcatcttat atacatcacc
     6661 agcatcacta ttttttaaga ctaggcctat ataaacatcg ctcataaaga ctctttcaat
     6721 ttcgctgtct accttaatat cttttaaaag agttggatat tccttgatct tataaatact
     6781 caaaacattc tcaccaatag ctactgcaca tgtgtcattt ataaatttca ccttgggaac
     6841 taatgtgcta tcatactggt taaatccgcc aacaaccttt tccgtctcgt tctcccctac
     6901 atccgaaaag ctataaaaaa ctacattggt tttaattgaa tctccattca ccaacacata
     6961 tgatgccact agtttcgtcg catcatccga catgcttata tcaagtggat atccattctg
     7021 ggctagttct gtctttacgg tatacaatat tgaaccatct gtattataca acctaatgta
     7081 attcacattg gtatcctcga gtaccgctgc tgcaaggcct tgaatcgata cctcgatttg
     7141 tgatatcggc aatgaagtat ctacattgta tagaaaacct ttatcattaa agatatatat
     7201 gctgctacca ttaagatcac ctatcgctaa tgatttacca catattttga cttgtggcgc
     7261 tttcatctga tacgtctgat tccaaattgc ttcaccttta tttgtataac atgagatacc
     7321 atcattgcta tacctaatat atccattatt ataatcaata tattgtgccg cttccgtgtc
     7381 atctttgcta attgatttga ttattgtata accggaatat ttgatattat caaggctaac
     7441 cgccacgatt acagcgattg ctataaacgc aattacacat attccaatta ttatcgctat
     7501 cttaattcta tggttatgaa tctttttatg taacccatca tcatcatcat catcatcatc
     7561 gtcatcatct ctgccattaa aactattatt ataatcctta aaaactcctt taaccacatt
     7621 agacgaatta ctaggattag gattctttgc ttttttattt tctatatttt ttttaatttg
     7681 aagataatgt tttatatctg ccacaagaca ctcctcttat atacatactg actttattat
     7741 acagtattat ttaaattatt caaggaagtt ttatctcttg gccaataaat attttgtctg
     7801 ggtcatcaat tttgtttatc tccatgatct ctttatatct tagactatct ccatatattt
     7861 ttctgcagat gctcataagt gtatcaccct tttgtacaat atagctagct accggcttta
     7921 catcaactgg agtactgctt gttggtgcct gcgtctgcgc ctgagttgcc gctaccgttg
     7981 ccgatacctg cgtctgcgct tctgttggat atacgcctcc tacaatcttt ttcacagtgg
     8041 tacttgttgt ctcatcatct atcgaagttg ttgattttac gttcatatta gcaacttgct
     8101 gcactatttg atttaatgtt acgtcaagcc ctcgcatttt ctcgtaacta ttcatcatat
     8161 taattccaat cactaaaact acaactatca taaacgtact tatcccatac ataagtgaca
     8221 ttgttttttt ttgctcagca acttcctttt tttctgcaat aattgtccta aaattatgaa
     8281 tgacatcatc ttcaaccata ggatcaacac ttttacctgt gcgcttagcc agcatatatt
     8341 cttgcatgtc attatttctt tcataaaaac atacatatcc actctgcttc ttcaagcatt
     8401 ttccttcata aaaataaaaa tcctcttctt tttccgacgt attcaccaaa tatagggcct
     8461 tcatatttcc tgcaaagttg tctaaatgta tcttttcaag atttgacatg aaatccaacg
     8521 ttacatctgg tgttgttacg aaccatccag taatttctaa attatgaaaa tatttttcca
     8581 tgtcttcata tatcagagac catacatttt cactaaatgt aattcgattt tcatcttcat
     8641 ctatttcaat ttttactgca cctttaataa atacataact ttctccacct gactttttag
     8701 actctcctaa aagcaccccc actcttagct tgtccgaatc ttcgtatgcg atcgaattaa
     8761 tatatgtaaa tacataatcc tcaatgtaaa tttttttatt tgaatgcata tcccctattt
     8821 gcttaatgtt ttttggtctt ttaatatttt gttgttcatt taaactcttt ttttccccat
     8881 cattgcaaac tatttctatc atactacgtt tccctcctga ataagtatat tgggcacttc
     8941 aataccgtaa tattagcata tgcattttta gaaaattatc gttttatgtc agtagaaaag
     9001 aagaatttta tgacttaaat atacagaata tatcagatat gtttaaagat gtgctaagtt
     9061 ttcatttttt attgattaat atagtttttt ttatcctttt ttgtaaacaa caatatacat
     9121 agaaatgata ttttttcaat aaatatgtta ataatcattt aaaaactata aaatttatag
     9181 gagaggatat aaactctatg ttattttatt ataattcaga cttatcagag acaccgaggg
     9241 aaatgagttc tcaaatttct aaatttgttc accctgaaat cattggaaat agacaggtaa
     9301 ttgttctatg tataggaagc gatcgttcta ctggagacag cctaggcccg ttaattggct
     9361 ataagcttat taaaagtgga cttacaaacg tcaccatata tggttcatta aaaaatcccg
     9421 tccatgctac gaatcttaac gcaacaattg acgagattta taatttgtat aataaccctt
     9481 atgttattgc cattgatgct tcccttggta agaaggatca tattggctgt attacgcttg
     9541 gtactggtgc ccttaagccc ggacttggcg ttaaaaaaca actgccagaa gtcggagata
     9601 tccatattac tgggattgtt aatctttctg gggcaatgga tacattgctt ttacagacta
     9661 ccaggctttc taccattatg actttggctg atgttatttc tgaagcattg attaactcat
     9721 taaattaaca tcattgcttt tgttatatta ggttgtatta ttgggagttg tatttttgtt
     9781 ttatcatttt tgggttttat tatttttttg ttttatatac cgctattgcc tttccaattg
     9841 tttcggcacc gccagtattc attatttctg caagtgcctc caatttgtcg ggcgtagcaa
     9901 attcatttcc aagataggct tcataattag atgcaatata gattctttgc tccttaactt
     9961 tatcttccat ttctgtaagt aatgagtgtt ttttctctaa atccactttc aaagctatta
    10021 tacgttcttt atctttacct tcgatttctg caataatatt aggctttacc aaattattaa
    10081 agtcttcaag tgctaaagat ttctttgctt caaacttttc tatatccgtt attataatat
    10141 taatcttttc gtcaaactta tctagaccat acatttcttc atttttatct tttttaatag
    10201 catgcacaat tttacggatt tttcgcttgt tttcagttat tctatctttt gttttaatta
    10261 gcccttgaat aacctctaaa tgagggaact taattttctc gctaattagc ttatatattg
    10321 taaacacaat cgctacaagc acaatatata ttaagatcaa actccagtcc ggcatattcg
    10381 gaacgaaata atagatagct gaaggcaccg ctaaaaatgt tattagaaat gttactatgc
    10441 atataaaagc atctttaaac cctttagtca taaacaatgc caaaaacaga cggctattac
    10501 aaaatcttgg gattctattg cttttaaaag ccgccttaat ctcatccttc atacccttgt
    10561 tatcttctct aagcgatgaa gtttcaactg aaattctctc ttttacacct ttagactttg
    10621 ctttatccct gtctgattga atcttcttta acttttcttg gtcactttca atttctttat
    10681 caaaccctga tgcaacagct tcacgtcttg tcttaagtgt agattcaatt tcgtctctaa
    10741 ccgctttttc taaagattca atattcttct caagatcttt gactgctact ttaacaggtt
    10801 cgattttttc ttttgcaata ttatgctcct taatatcaga tttgatctgg ttaagacaaa
    10861 taatatcaca tgtcaatata ttttgttcct ccatacaacc atcctcctaa ttacgtcacg
    10921 tattaattat tctctctgta gaaattaata agacatccct caagaataat ctttcgttca
    10981 tcatctgtaa gttcacctaa cttaagttca aactctttaa gtgtatcccc tacgacaaaa
    11041 gctctaattg aatcgttttt attcttaacc gcttctttga ttcccggtac aaacaagtaa
    11101 tcaccctttt taaatggaag ttcgcccgct tttacaagga atgggagcat gccccaatta
    11161 ataagatttg aacgatatct ctttgttgca taatcatttg caatattcgc ccatcctcca
    11221 agaaccttct ggcaggaagc tgcttgttca cgtgctgatc catcgcctgg ttttactgcg
    11281 aaaatagcac ttccaattcc aatattcgta ttattgatat ctggataact cgctttgatt
    11341 ttatccatta tcgatttgat ttctggaaat gcttcttcag ggctttctcc tgcgattctg
    11401 gctttttcag caacatgaac ttctttggca cggccaacat atcctggatc ttttctagat
    11461 aaagtatatt ccgcaagtcc aagtggattt gaacgatatg atgaagtttc gcccgatgga
    11521 atcaattcat ctgttgttgt cactggatca tggatttctg caacaacctt taatactaaa
    11581 ttatctgtaa gtgctgacat ttcaggccaa tccttaatgt ttggtccaaa ttggatttcc
    11641 acatctggat cagggattcc tttgctatca aaaacacgat tttcgtaaat tgatttgtca
    11701 aagaaatact ttggattttt atattcaaca tctatatctg tagctgatgt caagaaccct
    11761 ttgttcgctg cagtcgctgc aattgaacgc gcatccataa gcgcaactga agaaatttgt
    11821 ccattttgta gcttagaccc ttcacggtta gggaagtttc tagtagaatg tctaatacta
    11881 aatgcattat tagcaggtgt atctccggct ccaaaacatg gcccgcaaaa tgcagtttta
    11941 acaattgcac ccgttccaag taaatcagct aaatcaccat ttctagcgag ttccatatat
    12001 attggtgtac ttgcaggata tacgctaagc gtaaattcat cattgccaat actcttattt
    12061 cttaaaatat cagctgctgc acaaatattt tcaaatccac cgccagcaca tccagcgata
    12121 ataccttgct caacatataa cttaccattt ctaactttat cttttaagct gtattcaact
    12181 tgaccgccta agcttacaag cgcttttttc tcacattcat ccaatatatc caaaagatta
    12241 gcgttaagct cttcaattgt atatgtgtta cttggatgaa atggcattgc gatcattggt
    12301 tttatctcgc ttaaattaac ataaatcatt ccatcataat aagttacatt tcctggattt
    12361 agttctttga agtctgcact tcttccgtga atgtcataaa attccttaat cttatcgtcc
    12421 gttttccaaa tagaggaaag acatgttgtc tctgttgtca ttacatcaat accaatacgg
    12481 aaatcggcac ttaaattaga aatacctggt ccaacaaatt ccattacttt attcttaaca
    12541 tagccattac caaatacttc tccaataatt gcaagtgcaa catcttgagg gcctacaccc
    12601 ttcattggtt caccagtcat atatacacca acaacgcctg gcatattaat atcatatgtt
    12661 ttgtcaagta actgcttcac gagttctggt ccaccttcac ccattgccat tgtacccagt
    12721 gcaccataac gcgtgtgact gtctgaacca aggatcatct tgccaccgcc tgcaagcatt
    12781 tctcttgcaa actgatgaat aactgcttga tgaggtggta catatattcc accatatttt
    12841 ttagcgcatg taagtccaaa catgtgatca tcttcattaa tcgttccacc aaccgcacac
    12901 aaactattat ggcagttagt aagtacataa ggaatcggga atttttcgag ccctgatgca
    12961 cgtgccgttt gaataattcc aacaaaagta atatcatgag aggttaattt atcaaattta
    13021 acctttaact tgtccatact tcctgacgta ttatgctttt ctaaaatttc ataagctaat
    13081 gtgtttttag cagcttcttt ctttgaaggt acattttcac ctaatttgct ctttaatata
    13141 gcagctatat ctgcaccatc ttcaatcact tcatttccat tgataagata cgctccgcct
    13201 ttactaagtt gtatcatcta aaatcctcct atttcataaa tatatgaatc aatttataat
    13261 accataaaat tacgcaataa aattggtatt gaatataata ttgaatataa ttataatatc
    13321 cagcttatat tcttgcaaat acttttcatc actattttta cttgaaccta ttctgaattt
    13381 tctttttcaa atcttttatt tcatcctcag aaatctttcc ttgattccaa gaaaacttaa
    13441 cattatcccc taaatatctt ggaataatat gcatatgaaa atgaaacact gtctgccctg
    13501 ctatttctcc attgttttgt aaaatattca taccatcaca atttagcgcc tctttaatcg
    13561 cttttgcaag tcttgttgcc actttaaata catgtgctgc agtttcttcg tcaatcgaat
    13621 ataaattatc aaaatgctcc ttgggcaaaa taattatatg tcccatagat gcgggtgata
    13681 aatcaaaaat agccttcaca atatcatctt cataaagcgc atttgtagga atatctccat
    13741 ttgctaatct gcaaaaaata caatcatctt ttctcattat atatccttct ctcctatcca
    13801 cttatttata atagaataat taacttgagt gtcaaactcc ttttataatg taaacaataa
    13861 atattaattt ataacaattt acaacaattt tcaattaatt tttttataat atgtcaaaat
    13921 atgtcgcaaa ccttttattt acataatttt acataaagcg tatactcatt aacatatata
    13981 atagcttaga agcaagcata tatcaatact atttttagct tatattgata tcttgtctat
    14041 acgagaggag tcacttatga ttagtgaaaa a
//
