LOCUS       c00001_NZ_RKHR..       22493 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_RKHR01000003.1 Sinobacterium caligoides strain DSM 100316
            Ga0244720_101, whole genome shotgun sequence.
ACCESSION   NZ_RKHR01000003
VERSION     NZ_RKHR01000003
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:42:41
            Original ID  :: NZ_RKHR01000003.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 271634
            Orig. end    :: 294127
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22493
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[281634:284127]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12493
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..22493
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..22493
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Fumarate2succinate"
                     /region_number="2"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(20..1198)
                     /locus_tag="ctg1_236"
                     /transl_table=11
                     /translation="MKLVTDIWRALSKPAKHLTLGTIAISAFIMGIIFWGGFNTALEAT
                     NTEEFCISCHEMGDNVYKELQETVHYSNHAGVRATCPDCHVPHNWTNKIARKMQASKEV
                     FAKLTGAINTREKFLNKRLELASHEWARFEANGSLECKQCHSYKSMKWEEMSKLAQKQM
                     KRAAKRDQSCLDCHKGIAHHLPDMAASRAPELIAEVGEGPSKFDDGEQYFSSLTKPLYL
                     SADATEEAGLLNIATEVTVLETKGDRIKLHIDGWRKRIGAGRVIYFGFGINMNSAQLTM
                     TAAKTDGVIKVFEDKVDEMTGLTWERVEVTAWTDADYMLKEQQPLWDYAKTTFQSSCSV
                     CHTQPAENHFDANTWPGMFQGMMAFVNFDQDTEALVQKYLQAHSSTFSKEKH"
     CDS             complement(1244..1411)
                     /locus_tag="ctg1_237"
                     /transl_table=11
                     /translation="MTKDSTDNDEKKNELKALAFITIFLFPILSIIGVGGYGFIIWMLQ
                     IIFGPPGHGL"
     CDS             complement(1780..2655)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Ligase_CoA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CoA_binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_238"
                     /sec_met_domain="Ligase_CoA (E-value: 7.8e-22, bitscore:
                     74.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="CoA_binding (E-value: 1.2e-32, bitscore:
                     108.8, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVLINKDTKVICQGFTGGQGTFHSEQAIAYGTNMVGGVTPGKGG
                     TEHLGLPVFNTVAEAVEVTGADASVIYVPAPFCKDSILEAANAGIKLIVTITEHIPVLD
                     MLECKVRCDELGVRLIGPNCPGVITPGECKIGIMPGHIHLPGKVGIVSRSGTLTYEAVK
                     QTTDYGFGQSTCVGIGGDPIPGTNFIDVLEMFQNDPQTEAIVMIGEIGGTAEEEAAAYI
                     KANVTKPVVSYIAGVTAPAGKRMGHAGAIISGGAGTADEKFAALEDAGVKTVRSLAQIG
                     DALSEITGWK"
     CDS             complement(2662..3822)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GARS_A"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Ligase_CoA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_239"
                     /sec_met_domain="GARS_A (E-value: 1.4e-06, bitscore: 24.5,
                     seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Ligase_CoA (E-value: 5.2e-26, bitscore:
                     87.6, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLHEYQGKQLFAEYGLPVSKGFACDTPEEAAEATQKIGGDMWVV
                     KAQVHAGGRGKAGGVKLIKSADEAKAFAEKWLGQNLVTFQTDENGQPVSKVLVETCTDI
                     ADELYLGAVVDRSSRRIVFMASTEGGVEIETVAHETPEKILKCEIDPLVGAQPYQGREL
                     AFKLGLNKTQVGQFVKIFMGLAKLFEEKDLALIEINPLVIKEDGDLHCLDAKLGVDGNS
                     LYRQKKIADMNDPSQEDAREAEAAKWDLNYVALDGNIGCMVNGAGLAMGTMDIVALHGG
                     SPANFLDVGGGATKERVAHAFKLILSDEKVKCVLVNIFGGIVRCDMIAEGIIGAVKEVG
                     VTVPVVVRLEGTNADLGKEVLKNSGLDIIAATSLTDAAEQAVKAAG"
     CDS             complement(3983..5431)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_dim"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_240"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1e-70, bitscore:
                     234.5, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="Pyr_redox_dim (E-value: 8.6e-40, bitscore:
                     131.7, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDSYDVVVIGAGPGGYVAAIRAAQLGFKTLCVEKWLNDEGKTSL
                     GGTCLNVGCIPSKALLDSSHKYHEARDDYALHGITHNDIAIDVKAMVARKDAIVSQLTG
                     GIAGLFKANGVELAEGSAKVLAGKKVEITAHDGSVKVVDATSIIIASGSSPVNIPPAPL
                     FEDIVLDSTGALKIDETPKRLGVIGGGVIGLEMASIWNRLGTEVVVIEAMDDFLAMMDG
                     QVAKEARKLLKKQGLDIRTGALVTGTEVDADKREVTVTYKDAKGVQTEVFDKLIVAVGR
                     RPHTENLLAADAGVKLDERGFIFVNDFCETEMPGIYAIGDVVRGPMLAHKSSEEGIVAV
                     ERIAGKKAQMNYDCIPSVIYTHPEIAAVGKTEEQLKAAGDAYKVGVFPFAASGRAMAAN
                     ETAGFVKILADEETDRVLGAHIIGPSAADLIQQVVIAMEFGSSAEDLGMIVFGHPTLSE
                     AVHEAALAVDGHAIHIANRKKRKK"
     CDS             complement(5561..6763)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) oxoacid_dh"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_241"
                     /sec_met_domain="Biotin_lipoyl (E-value: 4.4e-18, bitscore:
                     61.2, seeds: 40, tool: rule-based-clusters)"
                     /sec_met_domain="oxoacid_dh (E-value: 6.6e-83, bitscore:
                     274.0, seeds: 75, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIEIKAPQFPESIADGTIASWVKQPGEACTRDELIVEVETDKVT
                     LEILAPADGVIREIVKAEDDTVLSEELIGYFEEGAAAATPEAAAPVAAQASVSSSAADV
                     KLSPAARKMVDEQGIDASSIVATGKGGLITKEDVVAATKKPAAAVAPAPTPAAKPVIEV
                     DAGERVEKRVPMTRMRSRIAERLLDATQSTAMLTTFNEVDMGPIMELRKQYKDMFEKKH
                     NGTRLGFMSFFVKAATEALKRFPAVNASIDGNDVVYHGYQDVGIAVSTEKGLVVPVLRD
                     TDQMGLADIEAGIRNYGLRARDGKLGIEDMTGGTFTITNGGVFGSLMSTPILNPPQAAI
                     LGMHKIQERAMVVDGEVVVRPMMYLALSYDHRLIDGKNSVQFLVTIKELLEDPARILLE
                     I"
     CDS             complement(6882..9710)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) E1_dh"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transket_pyr"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_242"
                     /sec_met_domain="E1_dh (E-value: 1.3e-53, bitscore: 178.1,
                     seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="Transket_pyr (E-value: 1e-67, bitscore:
                     223.5, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQESIMELLWSSSHISGGNSAYVEDLYEQYLLDPNSVPEDWRTYF
                     EKLPRVEGVVNQDTPHSPVVEHFELLGKSRLRPAAASSEGVSTEYERKQVRVVNLIESY
                     RNRGHQKATLDPLGLWQRQLPADLDIHFHQLSAADLDTTFQTSNLFSNKSEATLKEVID
                     ALESTYCGNVGVEFAHITSHEEQQWLQQRMESVRAKPEYGDEVKRHILERLTAAEGLEK
                     YLGSRYPGTKRFGLEGAESLIPMLDELIQRAGSYGVQEVVIGMAHRGRLNVLVNTLGKN
                     PRELFDEFDGKANYVGSADVKYHQGLSSNVMTSGGEVHLAMAFNPSHLEIVSPVVEGSV
                     RARQDRRDAPEQVLPVVAHGDAAFAGQGVVMETFQMSQTRAYKTGGTVHIVINNQVGFT
                     TSNVEDSRSTEYCTDVAKVIQAPIFHVNGDDPEAVIFATQVALDFRQEFKKDVVLDLVC
                     YRRRGHNEADEPSGTQPQMYSKIREQRTTRELYVDSMIAQGIISADQDKQAVDGYRNAL
                     DNGNHVAKSLVLEPNTGMFVDWAPYIGHDWTAYADTRVDQDKLKELALRLSDIPEGVTL
                     QRQVSKIVEDRKKMASGALPVNWGFAETMAYATLLDEGHPIRLTGQDVGRGTFSHRHAV
                     LHNQKEKNCYVPLQHLAENQPAFSIHDSLLSEEAVLAFEYGYATTMPNALVVWEAQFGD
                     FANGAQVVIDQFITSGEHKWQRLCGLTMLLPHGYEGQGPEHSSARLERFLQMCAEHNIQ
                     VCVPTTPAQVYHMLRRQVIRPLRKPLIVMSPKSLLRHKQAVSTLQELAEGSFQTVIGEA
                     DEIADDQVKRLVLCSGKVYYDLYNMRAEHELEGVAVVRLEQLYPFPEEGMMAELSKYPN
                     LETMVWCQDEPQNQGAWYSSQHHMRRVLAAHNQDCQLEYAGREASASPAAGYMALHLAQ
                     QDKLLKDALGLV"
     CDS             complement(10001..10708)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 101; E-value: 1.2e-31)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_243"
                     /sec_met_domain="Fer2_3 (E-value: 2.5e-30, bitscore: 101.0,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 4e-11, bitscore: 39.6,
                     seeds: 82, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKVSIYRYNPATDSEPKMVDYELDTQGKDIMVLDVLEQLKAEDS
                     SIAFRRSCREGVCGSDGLNINGKNGLACIMPLSEAGLRGGKLVIRPLPGLPVIRDLVVD
                     MEMFYDQYKKIKPYLLNDTPAPAIERLQSPEEREKLDGLYECILCACCSTSCPSFWWNP
                     DRFIGPSGLLQAWRFLVDSRDTATEERLAGLDDPFSVFRCHGIQSCVNVCPKGLNPTRA
                     IGHIRNMLLANAT"
     CDS             complement(10724..12493)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 403.8; E-value:
                     3.2e-123)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_244"
                     /sec_met_domain="FAD_binding_2 (E-value: 6.7e-122,
                     bitscore: 403.8, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 6.2e-42,
                     bitscore: 138.9, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIRTISFDAIVVGGGGAGMRAALQMAQSGYNTAVVTKVFPTRSH
                     TVSAQGGITCAIASNDPNDDWRWHMYDTVKGSDYIGDQDAIEYMCSVGPEAVYELDHMG
                     LPFSRTEEGRIYQRPFGGQSKDFGKGGQAARTCAAADRTGHALLHTLYQSNLKSNTQFL
                     NEWYAVDLVKNAAGDIVGCIAICIEDGETVFIKSKATVLATGGAGRIFASTTNAHINTG
                     DGIGMALRAGIPVQDIEMWQFHPTGIHGAGVLVTEGCRGEGGYLINKDGERFMERYAPN
                     AKDLAGRDVVARSMTLEILEGRGCGPDGDHVYLKLDHLGEEVLHSRLPGICELSITFAH
                     ADPVKVPVPVVPTCHYMMGGVATNIHGQVLTVDDSGQDVVINGLYACGEVACVSVHGAN
                     RLGGNSLLDLVVFGRAAGIYIEKALREGIEMDAATDADVEKAMARLNRLNSASDGDKVS
                     DLRKELQTIMQNHFGVFRRGDFMQEGIKKLAELRTRIENCRLDDKSAAFNTARIEALEL
                     QNLFEVAEATAVAAEERKESRGAHARDDFQDRDDENWLCHSMYFPGEKRVSKRAVNFKP
                     KTVPTFEPMERKY"
     CDS             complement(12493..12864)
                     /locus_tag="ctg1_245"
                     /transl_table=11
                     /translation="MSVTSVTTYGRNGLADWLVQRVTAVVLLAYFVFLTVFIACNEITF
                     ALWSALFAETWMRVFSMMALLSLCAHAWIGLWGVSTDYMTARMMGAKGNLVRWVFQSVV
                     AVVTFTYLVWGVQILWSVS"
     CDS             complement(12861..13235)
                     /locus_tag="ctg1_246"
                     /transl_table=11
                     /translation="VKDNRPVNLEIGTMKLPLTAYASILHRISGVFIFAGVALLLCLLG
                     SSLESEESFRAAQESLQSPVAKFALWVVLAGLIYHLVAGTKHLIMDMGIGESLEGGLLG
                     AKLTIAISAVLIILAGVWIV"
     CDS             13721..14998
                     /locus_tag="ctg1_247"
                     /transl_table=11
                     /translation="MSERTATLKLDDLEEALELPVMSGTIGPDVIDVGGLTAKGYFTYD
                     PGFVSTASCESKITYIDGGKGVLLHRGYPIEQLAEKSDFLETCYLLVYSKLPNKEEKTK
                     FINNIRYHTMVHDQLSHFFNGFRRDAHPMAIMCGVVGALSAFYHDSLDITDERHREISA
                     QRLIAKMPTLAAMTYKYSIGQPFVYPRNDLNYAENFLYMMFSNPCEEYKVNPVLSKAMD
                     RIFLLHADHEQNASTSTVRLAGSTGANPFACISAGIAALWGPSHGGANEAVLAMLDEIG
                     DVSNIDEFVARAKDKNDPFRLMGFGHRVYKNFDPRARVMKETADEVLAELGLEDSPLLK
                     IAKRLEQIALEDPYFIEKKLYPNVDFYSGIILKALGIPTSMFTVIFALGRTPGWIAHWH
                     EMISHPYKIGRPRQLYTGPAKRDYPE"
     CDS             complement(15174..16550)
                     /locus_tag="ctg1_248"
                     /transl_table=11
                     /translation="MFGAKEKSKNVGKVFYAPWEKAFDRVLTPFDEFIHRQSTSGLILM
                     TMAVVALLLANSPLSAGYENILKTYFKLSFGGFELKLSLQHWINDGLMAYFFLLVGLEL
                     KREFLVGELADTKKAVLPIMAAIGGMVIPAGLYAVFNIGGPGAGGWGIPMATDIAFAVG
                     IITLMGNTVPKSLVTFLVALAIVDDLGAIAVIAVFYTEQLNFAAAAWVGALTFLLVAMN
                     FGGIRRTGPYMFVGVLLWFALLKTGIHATLAGVVVAFTIPAMPKFDAVAFATKVKRSAV
                     RIGDSANLGIDIMRNDELRANAQSLKSGIELAQAPLQKVEHGLHTPVTYFIVPLFALAN
                     AGIPFSAFSGDVSLLNNVTLGVIVGLFFGKLIGIAGAVWLGRSFGLGLLPKGCNMMHIV
                     GVALLGGIGFTMSIFIAELAFAGSEQLILAKGGILIASLLSGIFGYIALKYAGKSKPGR
                     "
     CDS             complement(16740..17930)
                     /locus_tag="ctg1_249"
                     /transl_table=11
                     /translation="MRIITIVFFSQLMSFMAVAETLPEGMVLNGVAEFKELNRSYFVGA
                     LYLEEPANTAEAVQALASTRRMMEIRVTAKRWSPRRFSSQWTQLIVANNEEAMLNRYSD
                     EFIAFNNMARFSLKRGDTLLFDQSPDGKIVIHVNGVKTASYDRIGSFDMLLNTWIGKRP
                     PSTEFKQSILGAVDNAGALSLYEATTVQPERRDIVVQWMGAMQQLAMAAGSGEVPAASL
                     GGLANATTEAVDAASTLEIVPDKIESTKPASQSIVVEEKEVVAELVEESVAVEEELVDD
                     LELGDDFDIDPEIIQQQHDMMLKLYRSSIVKQTLRKVQYPSRAIKRGLEGLVVVEVRLD
                     RFGKRLSAERVQSAKYSLLNKAAMAAVSSVESYPAAPIALKGDVISVKVPIRFALN"
     CDS             18320..18955
                     /locus_tag="ctg1_250"
                     /transl_table=11
                     /translation="MIRITIFSLILLITACSSQPMKPKDITGLWLKASKNGEPEGFYLG
                     PQGDLQLYNIFSWLGESWGIEGKSLLWLTATEQVPSPELSELHYSLKGDNLIISEGSYF
                     NGEYQRAAVQILCGSVNILQQADDQQLSITLIQEDKKSTINQKLISRKVIANPETATPF
                     TLAIASDLINDKQPYRLLLVLSDGRTIISRQSIEYTKLPGQCVAPIDL"
     CDS             complement(18975..19520)
                     /locus_tag="ctg1_251"
                     /transl_table=11
                     /translation="MALKSTVYKIQLQVSDMNRHYYAEHHLSVACHPSESLLRMLTRII
                     VFGLNADEKLTFGRGLSEVDDAPLWLKDDTGEVKLWIEVGSPSVDRMMWLRGKSDTYAN
                     YSYQESSRVWWAKHGAELSVLDKCEYYLLPEALLKTLTGGIKRQMKIGLLVTDDTIMLT
                     GDLEAEFLLEKMDSLEIG"
     CDS             19551..20000
                     /locus_tag="ctg1_252"
                     /transl_table=11
                     /translation="MPILTLSETRIINATPTQVFQTVIGIDHYHRWNPWLKEAKGSVKP
                     GDSVRVKVDLGRDKLEEYNHTILAYKTDKYFAWEDKGWFTFLTKGSRHRYFSLTEEGAT
                     HYRVELNLSGLFAGLAQRKFGAALSKGLAAEADALKNYCEAMTSN"
     CDS             20097..20240
                     /locus_tag="ctg1_253"
                     /transl_table=11
                     /translation="MSPSAPHTDSHSLLEVGTNSNHKKSVLYSWSLLTITLVEKDTTLQ
                     NK"
     CDS             20300..21079
                     /locus_tag="ctg1_254"
                     /transl_table=11
                     /translation="MTNSKYPLLFLAHGSPMNAIEDNPFSRDWHKLYIGTPSPKAVIVI
                     SAHWESNGTYITHHRSPPTLHDFSGFPAQLNQLRYACPGAPILAEEVHRRVPSIQLDQQ
                     RGLDHGCWSLMNQLFPRANIPTLQISLNRKLSPQQHWDLAKQLKWLRQEEVLILCSGNI
                     VHNIAAWQAWMSGNINDVTWAGSFDKTIYNALKNSDTSSLIHYSEHYGSELSVPTAEHY
                     LPLIYADAIRDKKDPLISSTPSINSFEASCSRSIRFG"
ORIGIN
        1 tgctcatgct gactctacct taatgctttt ctttagagaa cgtggatgaa tgcgcctgca
       61 agtacttttg cactaaggcc tcggtatctt ggtcgaagtt aacaaaggcc atcattccct
      121 ggaacatacc tggccaagta ttagcatcaa aatgattttc cgcaggctgc gtatggcata
      181 ccgaacaaga agactggaac gttgtttttg cataatccca aagtggttgc tgctctttca
      241 gcatgtaatc agcatcagtc cacgccgtca cttcaacacg ctcccaggtc aaccccgtca
      301 tctcatcgac tttatcttca aagactttga tgacgccgtc tgtctttgct gcggtcattg
      361 tcagctgcgc tgagttcata ttgataccaa agccaaagta aataacacgc cccgcgccaa
      421 tccgctttct ccagccatca atatgtaact taatccgatc gcccttggtc tctaaaacag
      481 tcacctctgt tgcaatattc agcaggcccg cttcctctgt cgcatcagca gagaggtata
      541 gaggcttcgt taacgagctg aaatattgct cgccgtcatc aaacttagat ggtccctcac
      601 ccacttccgc tataagttca ggtgctcgag aagctgccat atcaggtagg tggtgagcaa
      661 ttcccttgtg gcaatcaaga cagctttgat cacgcttcgc agcacgcttc atttgcttct
      721 gggcaagctt cgacatctct tcccatttca tcgacttata actatgacac tgcttgcact
      781 ctaaagagcc attggcttcg aaacgcgccc actcatggct ggccaattct aagcgcttat
      841 taagaaattt ctcacgggta ttgatagcac ctgttaattt agcaaacacc tctttcgatg
      901 cctgcatctt cctggctatt ttgttcgtcc agttatgcgg tacgtgacaa tcagggcaag
      961 tggccctgac gccggcatga ttactgtaat gaaccgtctc ctgcagctcc ttgtaaacat
     1021 tgtcacccat ctcatgacag ctaatacaaa attcttctgt attcgttgcc tctaatgcag
     1081 tgttaaagcc cccccaaaag ataatcccca tgatgaatgc agaaattgcg atggtgccca
     1141 gcgtaagatg ctttgcaggc ttggatagcg cacgccagat atcagtgact agtttcatct
     1201 gatagtttcc ctttgataac gatggaaaga agaagtgtag ggtttacaga ccgtgccctg
     1261 gcgggccgaa aattatttgc aacatccaaa taataaagcc atacccccct actccaataa
     1321 tgctcaggat tggaaaaagg aagatggtaa taaacgccaa cgcctttagt tcgttcttct
     1381 tctcatcgtt atcagtagaa tctttagtca tattattcag caccttaatc tgcaacatat
     1441 ccctgcatgg tctgaccgaa gccaacgcaa tcacatcatt gttacgagta gcttcgctaa
     1501 tgccagctta gacaacaaaa cgccctactt ccaacagcca gaaagatgtg cgcagcgaac
     1561 acattaacaa ctacccatat aaatatgagc gcattttatg cctcttagga acaactttac
     1621 tgactcaaat caactgaaaa cagctcgcaa aacacatcct cttgttgctt gctctacatc
     1681 attaatagaa ttaaatttct caccaaataa aaaacttaga cacaaaaaaa ccgcccttag
     1741 gcggtttttt aaacgagtac tattagaagc taataagcac tacttccaac cagtgatctc
     1801 agaaagtgca tcaccgattt gcgcaagaga acggacagtc ttaacgcctg cgtcttcaag
     1861 ggcagcaaac ttctcatcag cagttccagc accgccagag atgattgcac cagcatgccc
     1921 catacgctta cctgcaggtg cagtaacacc ggcaatgtaa gagacaacag gcttagtcac
     1981 gttagcttta atataagcag ccgcttcttc ttcagcagta ccaccgatct caccgatcat
     2041 cacgatcgcc tcagtctgtg gatcgttctg gaacatttcc agtacgtcga tgaagttagt
     2101 acctgggatt ggatcaccac cgataccaac acaagtagac tgaccgaaac cgtagtcagt
     2161 agtctgctta acagcttcat aagtcagcgt acctgagcgc gatacgatgc caaccttacc
     2221 cggcaggtga atgtgaccag gcatgatacc gatcttacat tcgcccggtg taataacacc
     2281 aggacagtta gggccgatca ggcgtacgcc caactcatca cacctaactt tacactccaa
     2341 catatccaac actggaatgt gctcagtaat ggtgacaatc aacttgatac cagcatttgc
     2401 cgcttcaagg attgagtcct tacagaaagg agcaggcaca tagataacag aggcatcagc
     2461 acccgttact tcaacagcct cggcaacagt attaaaaact ggcagaccta ggtgctcagt
     2521 gccaccctta ccaggtgtaa caccgccaac catgttggta ccataagcaa ttgcttgctc
     2581 agagtgaaaa gtaccctgac cgccagtgaa accctgacag atgactttag tatctttatt
     2641 aattagtaca gacattgata attaccccgc cgccttaact gcttgctcag cagcatcagt
     2701 cagacttgtt gctgcaatga tgtctaggcc agagttctta agaacctctt tacccaaatc
     2761 agcgttagta ccttccagac gcacaacaac aggaacggtt acaccaactt ctttaactgc
     2821 gccaatgatg ccttcggcaa tcatgtcaca acgaacgata ccgccgaaga tgttaaccaa
     2881 cacacacttc actttctcgt cagacagaat cagcttgaat gcgtgagcaa cacgctcttt
     2941 agtcgcacca ccgccaacat ctaagaagtt tgcagggcta ccaccgtgca gtgcgacgat
     3001 atccatagta cccattgcta gaccagcacc gttaaccata cagccgatgt tgccatcaag
     3061 cgctacgtag ttaagatccc atttagccgc ctcagcttca cgagcatctt cttgcgaagg
     3121 atcgttcatg tctgcaattt ttttctggcg atacaaagag tttccatcaa cgccaagctt
     3181 ggcgtctagg cagtgaagat caccgtcttc tttgataaca agagggttaa tctcgataag
     3241 agcaagatct ttctcttcga ataatttagc cagacccatg aatatcttaa caaattggcc
     3301 aacttgagtc ttattcagac ccagcttgaa cgctagctca cgaccttgat agggctgagc
     3361 accaaccaac ggatcgattt cacatttaag aatcttttca ggagtctcgt gagcaacagt
     3421 ttcaatctcc acgccacctt cagtagatgc catgaaaacg atacgacgag atgaacggtc
     3481 aacaaccgca cccaagtata attcgtcagc gatatcggtg caggtttcta ctagaacctt
     3541 agaaactggc tgaccatttt cgtctgtctg aaaagtcact aggttctgac ccaaccactt
     3601 ttcagcgaaa gcctttgctt cgtcggcaga cttgatgagc ttaacaccac ccgccttacc
     3661 acgaccacca gcgtgaactt gagctttaac aacccacatg tcgccgccga tcttttgagt
     3721 tgcttctgca gcttcttctg gggtatcgca agcgaaaccc ttcgaaactg gcagtccgta
     3781 ttcagcaaac aactgtttgc cttgatactc atgcagattc atatctcatt accgttttat
     3841 ttgtgctgat tgccagcacc tcactcttcc aacactgcct cgatatttgt tttttattcg
     3901 aaacaatgcc ccaaagacaa cctgtgctac taaaagcaac acagattgtc cttcttatta
     3961 gcgcaatgcg caaataaagt cgttattttt tacgcttttt tctgttcgcg atatgaatcg
     4021 catgaccatc cacagccagt gctgcctcat gaacagcctc tgaaagcgtc gggtgaccaa
     4081 acacaatcat ccccaagtct tcggcgctag aaccgaactc catcgcgata actacctgct
     4141 gaataaggtc tgctgcactt gggccaataa tgtgcgcacc caaaacgcga tctgtctctt
     4201 cgtcggcaag tatttttaca aagcctgccg tctcatttgc cgccattgca cgcccagacg
     4261 ctgcaaacgg gaatacgcca accttgtagg catctcctgc cgccttcagc tgctcttcag
     4321 tcttaccaac cgccgcaatt tcagggtggg tgtaaataac agacggaata cagtcatagt
     4381 tcatctgagc tttcttgccc gcaatacgct caacagcgac aataccttct tcagaagact
     4441 tatgcgccaa catcgggcca cggacaacat caccgatggc gtaaatacca ggcatttccg
     4501 tctcacaaaa atcattgacg aaaataaagc cacgctcgtc caacttaaca ccagcgtctg
     4561 ccgcaagcag gttctcagta tgaggacgac gaccgacagc aacgatcaac ttgtcaaaga
     4621 cttctgtttg aacgcccttg gcatctttat aagtcacggt cacttcacgc ttatcagcat
     4681 cgacctctgt acccgtaacc agtgcgccgg tacgaatatc aagcccttgc ttcttcagca
     4741 gcttacgcgc ttctttagcc acctgaccat ccatcatcgc caagaagtca tccatcgcct
     4801 cgatgacaac cacttctgtc cctagacgat tccagatgct cgccatctct aaaccgataa
     4861 caccaccacc gataacacca agacgcttag gcgtctcatc aattttcaag gcgccagtag
     4921 aatcgagaac gatatcttca aacagcggcg caggcgggat atttacagga gaagagccag
     4981 aagcaattat gatgcttgtc gcatcgacaa ccttaaccga accatcatga gctgtgatct
     5041 caactttctt accagctaga accttcgcag aaccctcagc cagctcaacg ccattcgcct
     5101 taaacaaacc ggcaatgccg ccagttagct gtgaaacgat agcatcttta cgtgcgacca
     5161 ttgctttaac gtcaatagcg atatcattgt gggtaatacc atgcagggca taatcatcac
     5221 gcgcctcatg atacttatga ctagagtcca gcaacgcctt agaaggaata catccgacgt
     5281 tcaaacaagt gccgccgagc gaggtcttac cctcatcatt gagccacttc tcgacacaaa
     5341 gagttttaaa accaagttgg gcagcgcgaa tagcggcaac ataaccacct gggccagcac
     5401 caataacaac gacatcatat gaatcagaca tggataacct tcttaaatta agtcctactc
     5461 tcgagagtag ggattggcac atacgcctac ccgcaatttt tatgctaagt agccgtaaca
     5521 aaaagaaagc ggcttatggc cgccttcttt catttttagc ttatatctct agcagtattc
     5581 tagcaggatc ttcaagtagt tccttaatag tgacgaggaa ctgcacagag tttttcccat
     5641 caatcaatcg atggtcgtaa gagagggcca aatacatcat cgggcgcaca acaacctcac
     5701 cgtcgacaac catcgcacgc tcttgaatct tgtgcatgcc gaggatagca gcttgtggtg
     5761 ggttgaggat aggcgttgac atcaacgaac caaaaacgcc accgttagtg atggtaaaag
     5821 taccaccggt catatcctcg ataccaagct tgccgtcacg tgcacgcaga ccgtaattac
     5881 ggataccggc ctcaatatca gccagcccca tctggtccgt gtcgcgtaaa acaggaacga
     5941 ccagcccctt ttcggtagac acagcaatac ctacatcttg gtagccgtga taaacaacat
     6001 cgttgccatc aatcgaagca ttgaccgcag ggaaacgctt aagcgcctca gttgccgcct
     6061 tcacaaagaa actcatgaag ccaaggcgag taccattgtg cttcttctcg aacatgtctt
     6121 tatattgctt acgcagctcc ataatcgggc ccatgtcgac ttcattaaaa gtcgtcaaca
     6181 ttgccgtact ttgcgttgca tctaacaaac gctcagcaat gcgcgaacgc atacgcgtca
     6241 tcggaacacg cttttcaaca cgctcacctg catcaacttc gattacaggc ttagccgccg
     6301 gcgttggcgc tggtgccacc gctgcagcag gcttcttcgt cgccgctaca acgtcttcct
     6361 ttgtgatcaa accgccctta cctgttgcca ctatgctaga agcatcgatc ccctgctcat
     6421 caaccatttt acgtgctgca gggctcaact tcacatcagc agccgagctt gacactgaag
     6481 cctgtgcggc aacaggtgca gctgcctcgg gtgtagcggc agcagccccc tcttcgaagt
     6541 agccgatcaa ctcttcacta agcaccgtgt catcttcggc cttaactatt tctcggataa
     6601 caccgtcggc tggcgccaag atttctaggg taactttatc cgtttcaact tctacgatta
     6661 gctcgtcgcg ggtacaggct tcaccgggct gcttcaccca ggaagcgata gtgccgtcag
     6721 cgatagactc agggaactgc ggtgctttta tttcgatagc catgttaatt ccttagaact
     6781 tgtctttctc gtcgtacgcc tcacttgtgc gcactacaaa agttatgtat tcgtaccact
     6841 taaacaaaga gccctgcatt aatataatgc agggccttca cttaaacgag cccgagggcg
     6901 tctttaagta acttgtcttg ctgggcaagg tgcaacgcca tataccctgc agctggagag
     6961 gccgatgcct cacgacctgc gtactctaat tggcaatcct gattatgagc tgccaacact
     7021 cggcgcatat ggtgttgcga ggaataccaa gccccctggt tttgcggctc atcttgacac
     7081 cacaccatgg tctctaaatt agggtactta gatagctcag ccatcattcc ctcctcaggg
     7141 aatgggtata actgctccaa acgcacaacc gcgacaccct caagctcatg ctccgcacgc
     7201 atattgtaaa gatcgtagta gaccttaccg ctacacaaca ctaagcgctt cacttggtca
     7261 tcagctattt catcagcctc accaataacc gtctgaaagc taccttccgc caactcttgc
     7321 aacgttgaaa cagcctgctt atggcgcaac aggctctttg gcgacatcac aatcagcggt
     7381 ttacgcagcg gtcgaatcac ctgacggcgt aacatgtgat aaacctgagc tggcgtcgtt
     7441 ggcacacaaa cttgaatatt gtgctctgca cacatctgca aaaaacgctc tagacgagcc
     7501 gaagagtgct caggaccctg cccctcatag ccgtgaggca gcaacatagt caagccacaa
     7561 agacgctgcc atttgtgctc accactagta atgaactgat caataacgac ctgcgcacca
     7621 ttggcgaagt caccaaactg agcctcccag acaaccagcg cgtttggcat cgtcgtcgca
     7681 taaccatact caaaagcaag aacagcttct tctgataaca gtgagtcatg gattgaaaag
     7741 gctggctgat tctctgcaag atgctgaaga gggacgtaac aattcttttc tttctggtta
     7801 tgcagaaccg cgtgacgatg cgagaacgtg ccacgcccaa catcctgacc cgttagacga
     7861 ataggatgcc cctcatcgag tagagtcgca taggccattg tctcggcaaa accccagttc
     7921 acaggcaacg cacctgaagc catctttttg cgatcttcga caattttgga aacttggcgc
     7981 tgtaaggtaa ctccttcagg aatatcactt aaacgtaacg caagctcttt cagcttatcc
     8041 tgatcgactc gcgtgtctgc gtaagccgtc caatcgtgac caatataagg cgcccagtcg
     8101 acaaacatac cggtattagg ctctagcacc agcgacttag caacatggtt accgttatca
     8161 agcgcatttc gataaccatc gaccgcctgc ttatcctggt ccgcgctgat aatgccttga
     8221 gcaatcattg aatcaacgta caactcacga gtagttcgct gctcacgaat cttgctatac
     8281 atttgtggct gagtacctga gggctcgtcc gcctcattat gacctcgacg acgatagcaa
     8341 accaaatcta agacaacgtc tttcttgaat tcctggcgga aatctaacgc aacttgagta
     8401 gcaaagatta ctgcttcagg gtcatcgcca ttaacatgaa agataggtgc ctgaataact
     8461 ttcgccacat cggtacaata ctcagtagaa cgagaatctt cgacattgct tgtcgtaaag
     8521 cccacctgat tattaatgac gatatgaact gttccacctg tcttataagc tcgagtctga
     8581 gacatctgaa acgtctccat gactacaccc tgtcctgcaa aagccgcatc accatgagcg
     8641 acaacaggca gcacctgctc aggcgcatct cttcgatcct gcctagcgcg aacagagccc
     8701 tcaacaacag gcgatacaat ttccaaatga gatgggttaa aagccatggc aagatgaact
     8761 tcaccaccac tggtcatcac attagaagat aggccctgat gatatttcac atcagctgaa
     8821 cctacatagt tggctttgcc gtcgaactca tcaaataact cacgaggatt tttacctagc
     8881 gtattgacca gaacattcaa acgaccacgg tgcgccatac ctatgacgac ttcttggaca
     8941 ccgtaagagc ctgcacgctg aataagttca tccaacatag ggataagact ctcagccccc
     9001 tctaaaccaa aacgttttgt gccgggatag cgcgagccaa ggtacttttc tagcccttcc
     9061 gccgctgtta agcgttccag tatatggcgt ttaacctcat caccgtactc aggcttggca
     9121 cgaacggact ccattcgctg ctgcaaccat tgttgctctt catgagaggt gatatgtgca
     9181 aactcaaccc ccacgttgcc gcagtaggtt gactctagcg catcaataac ctctttaagt
     9241 gtcgcttccg acttgttact aaagaggttg gatgtttgga aggttgtatc gagatcagca
     9301 gctgaaagct gatgaaaatg aatatcgaga tcggcaggca attggcgctg ccataaccct
     9361 aacggatcta gtgtagcttt ttgatggcca cgattccggt aggattcaat caggttaaca
     9421 acgcgcacct gtttacgctc atactcagta ctaacgcctt cactgcttgc cgcagcgggc
     9481 cttaaccttg acttaccaag cagttcaaaa tgctcaacga cgggggagtg aggagtatct
     9541 tgattgacaa caccctccac ccgaggaagc ttttcgaaat aggtgcgcca gtcttccggt
     9601 acagaattag ggtccaacaa gtactgctcg tagagatctt ctacgtaagc agagttaccg
     9661 ccacttatat gtgaactgct ccacagcagt tccatgatgc tctcttgcat tatcacacac
     9721 cttaagatgg gagcaattat taacccaaaa gctaagcgct gatgtagcac caaatagcaa
     9781 atcgagaata cctgagcatt ccaaccgatc gacctaagcc tccgataata atcgggattt
     9841 tatccgcaac ccccgaggga tacagctttt tatttagcct caaaccatcc agcaagatgg
     9901 tcgaccaccc ttaccattaa gacggatctc actctgcctt aaatcgggcg gaggcattgt
     9961 aaaacacctc cacccaaacc actagggcta acgctacatt ttacgtggca tttgctagca
    10021 gcatatttct gatatgacca attgctcggg ttggattaag acccttagga cacacattga
    10081 cacaactttg aataccatga cagcggaaaa cgctgaacgg gtcatcaagg cctgcgagac
    10141 gctcctcagt agccgtatca cgactatcaa caagaaaacg ccacgcctga agcaagccgc
    10201 ttggaccgat aaaacgatcg ggattccacc agaacgaagg gcatgatgtc gagcaacagg
    10261 cgcagagtat acactcatac aagccatcaa gcttttcacg ctcctcaggt gactgcaagc
    10321 gttcaatggc tggcgctggc gtatcattca gcagataagg cttgatcttc ttgtactggt
    10381 cataaaacat ttccatgtct acaactagat cacgaataac cggcagccca ggtaacggac
    10441 gaatgactaa cttgccaccg cgcaagcccg cctcagacaa tggcatgata caagctaagc
    10501 catttttacc gttgatatta agaccatcag aaccacaaac accttcacga cacgagcgcc
    10561 taaaggcgat acttgagtcc tcagctttaa gctgctcaag cacatccaac accataatat
    10621 ctttgccctg ggtatccaac tcataatcaa ccattttagg ctcagagtcg gtcgcagggt
    10681 tgtagcgata aatagaaact ttcaacattt tcctgctccc ttattagtac ttacgttcca
    10741 tcggttcaaa cgtcggtacg gtcttcggct tgaagtttac cgcacgctta gaaactcgct
    10801 tttcaccggg gaagtacatt gagtggcaca accagttttc atcatcacga tcctggaagt
    10861 catcacgagc atgagcgcca cgactctcct tacgctcctc ggccgctaca gctgtcgcct
    10921 cagccacctc aaacaagttt tgcagctcga gcgcctcgat acgcgccgta ttaaacgccg
    10981 ccgacttatc atctaagcga cagttttcaa tacgtgtacg cagctccgca agcttcttta
    11041 tgccttcttg cataaagtct ccacgacgga acacgccaaa gtggttctgc ataatagtct
    11101 gcaactcttt acgcaagtca ctgaccttat caccatcaga ggcgctgtta aggcgattca
    11161 agcgcgccat agccttctcg acatccgcat ctgttgccgc atccatctca ataccttcac
    11221 gcagtgcttt ttcgatatag ataccggcag cacgcccaaa aacaacaaga tcaagcaacg
    11281 agttaccgcc taagcgattg gcaccatgca cagaaacgca ggcaacctca ccacaggcat
    11341 atagaccatt aataacgaca tcctgaccgc tatcatccac agtcagcacc tgtccatgaa
    11401 tatttgtagc cacaccaccc atcatataat gacaagtagg aactacaggc acaggcacct
    11461 taacaggatc agcgtgtgcg aaagtaatcg acaactcaca gattcctggt agacggctat
    11521 gcaaaacctc ttcaccgagg tgatcaagct taagatatac gtgatctcca tccggcccac
    11581 aaccacgccc ttcaagaatc tctagtgtca tggaacgcgc cacaacatca cgacccgcca
    11641 aatccttagc gttaggtgca taacgctcca taaaacgctc accatccttg ttaatcaggt
    11701 aaccaccctc tcctcgacaa ccctcggtaa ccaaaacacc ggcaccgtga atacctgtcg
    11761 ggtggaattg ccacatttcg atatcctgaa caggaatacc tgcacggagc gccatgccaa
    11821 taccgtcacc cgtgttgatg tgcgcattcg ttgtagaggc aaagattcga ccagcaccgc
    11881 cagtcgccag aacagtcgct tttgacttga taaagacggt ctcgccgtct tcgatacaga
    11941 tcgcgataca accaacaata tcgcctgccg cattcttgac caaatcaacc gcataccact
    12001 cattcaagaa ctgagtatta ctcttcaaat tactctgata aagcgtgtgt agcagcgcat
    12061 gaccagtacg gtcagcggcc gcacaagtac gagcagcctg accaccctta ccaaaatcct
    12121 ttgactgacc accaaaagga cgctgataga tacgcccctc ttctgtacga gaaaaaggta
    12181 gacccatgtg atctaactcg tagacggcct cagggccaac agagcacatg tattcgatag
    12241 catcctggtc accaatgtaa tcagaacctt tgacagtgtc atacatatgc caacgccagt
    12301 catcattcgg gtcattacta gcgattgcac aggttatacc accctgagct gacacggtat
    12361 gcgaacgcgt cgggaaaact ttagtgacga cagccgtgtt ataacctgac tgagccattt
    12421 gtagcgcggc acgcatgccc gcaccgccac caccaacaac gatggcatca aaagagatag
    12481 tgcgaataga cattacgaca cgctccacaa aatctgaaca ccccaaacga ggtatgtaaa
    12541 ggtcacgaca gcaacaactg attgaaagac ccaacgaacg agattacctt tcgcacccat
    12601 catacgggca gtcatgtaat cagtagatac tccccacaga ccaatccagg catgcgcgca
    12661 caacgacagc aacgccatca tgctaaagac gcgcatccag gtctctgcaa acagagcact
    12721 ccagagcgca aaagtaattt cattgcaggc aataaaaaca gtaagaaaaa caaagtacgc
    12781 caacaagaca acggctgtta cgcgctgaac tagccaatcg gccaagccat tacgcccata
    12841 cgtagttaca gatgttacac tcatactatc cacacccccg caagaataat cagtacagct
    12901 gagatggcga tagtcaactt agcacccagc aaaccaccct ctagtgattc accgataccc
    12961 atatccataa tcaggtgctt agtaccagcc acgagatgat agataaggcc agctaaaaca
    13021 acccacagcg caaactttgc gacaggagac tgcagacttt cttgtgcagc acggaagctc
    13081 tcttcgctct ctaacgaaga tcccaacaag cacagcagca aagctactcc agcaaaaata
    13141 aacaccccag agattctgtg tagaatcgag gcataggcgg taagagggag tttcatggtc
    13201 ccaatttcga gatttacagg tctattatct ttcacgacta gttacacttc tataatgccc
    13261 agttatgcag gcggttcatc gaaaagtgtt gaggcttgtc actttttaca aaggaggccc
    13321 catattatgt ttggaatcat cgattatccg gcattaaaat tacgcatttc gacaccaaac
    13381 aaccaaaatc cgcccgaaat tatatgctcg cgacgaggta attacaacgt catatgacag
    13441 atttaaaggg ccgagggtga ctattgcgca gcgcttatta gcaatatttt tcaaaatgat
    13501 agagcgcacc aaaacagtgc ctaaagcccc attatgaacg cgttatggac tgattccgac
    13561 taaccattga gtaatgctct cacgtcaagc ccttatgtac gaaaaaatac ctatatcgcg
    13621 acactccgct acattgacaa agaatttaat ccctctatag tgatgccgtc ctcaaaaggg
    13681 acacctctgt aatgtaagaa taagttatca ggagcccaat atgagtgagc gcacagcaac
    13741 tctcaagctg gacgatctag aagaagcact agaattgccc gtaatgtctg gcactatcgg
    13801 accagacgtg atcgacgttg gcggactgac agccaaaggt tattttactt acgatccggg
    13861 attcgtctcc accgcctcct gcgaatcaaa gatcacctat atcgatggcg gaaaaggtgt
    13921 acttctacac cgcggttacc ctatcgagca gctagccgag aaatcagact ttttagaaac
    13981 ctgctacctt ctcgtttata gcaagctacc aaacaaagaa gaaaaaacta agtttatcaa
    14041 caacatccga taccacacga tggtgcacga tcaactcagc cacttcttta acggcttccg
    14101 ccgcgatgcc caccctatgg ccatcatgtg cggcgtagtc ggcgcactgt ccgcttttta
    14161 ccacgactct ctcgacatca ccgacgagcg tcaccgcgag atctccgcac aacgcctaat
    14221 cgctaagatg ccaactctcg ccgccatgac ctacaagtac tctatcggtc aacctttcgt
    14281 ctatcctcgc aacgatttaa actatgctga gaacttcctc tacatgatgt tcagcaaccc
    14341 ctgcgaggag tacaaagtca accctgtact ctccaaggca atggatcgga tattcctgct
    14401 tcacgcagat cacgaacaaa acgcctcaac ctcaacagta cgccttgcgg gctcgacagg
    14461 cgccaaccca ttcgcctgta tctctgcggg cattgctgca ctctgggggc catcacacgg
    14521 cggcgccaac gaagctgttc ttgccatgct ggacgagatc ggtgacgtat caaatattga
    14581 tgagttcgtc gcccgcgcca aagataaaaa cgaccccttc cgcttaatgg gcttcggtca
    14641 ccgtgtttat aagaacttcg accctcgcgc tcgcgtgatg aaagaaactg ccgacgaagt
    14701 attggccgag cttggtctag aggacagccc tctactcaag atcgctaaac gactcgagca
    14761 aattgcattg gaagatcctt acttcatcga gaagaagctt tatccaaacg tcgatttcta
    14821 ctcaggcatc atcctgaagg cactaggcat tccgaccagc atgtttactg tcatattcgc
    14881 actaggccgc acgccaggct ggattgcaca ctggcatgaa atgatcagcc atccttataa
    14941 aattggccgc ccacgccagc tttataccgg accagccaag cgtgattacc ccgagtaatc
    15001 acgtaaagca aaaaaaaacc gcccttatgg gcggtttttt tttgctaata gaatattgcc
    15061 aaagactacg taaaagaaag ttaatctcaa cctagagcgc accaatataa tgcacaacaa
    15121 tcgcccaata gttaaagggc agcacaaaac caccccctta actcaaccaa tgtttaacga
    15181 ccaggcttac tcttgccagc atatttcagc gcaatataac caaagatccc tgagagcaac
    15241 gaagctatta agatcccgcc tttggccaaa atcaattgct cgcttcccgc aaaagccaac
    15301 tcagcgataa agatggacat cgtaaaaccg attccaccaa gcaaggccac accgacgata
    15361 tgcatcatat tgcaaccctt aggcagcaag ccgagcccga aagagcgccc taaccaaaca
    15421 gcaccagcga taccaatcag cttgccaaaa aacaagccga caataacacc aagcgttaca
    15481 ttatttagta acgaaacatc acccgaaaat gcagagaaag gtatccccgc attcgctagg
    15541 gcaaataaag gtacaataaa gtaagtcaca ggagtatgta aaccgtgctc aaccttctgt
    15601 aacggcgcct gggccagctc gataccactc tttaagctct gtgcattggc acgcagctca
    15661 tcattacgca tgatatcgat acccaaattg gcactatctc caatcctaac cgccgaacgc
    15721 ttaaccttgg tagcaaatgc cacggcatca aattttggca tcgcaggaat agtaaaggct
    15781 acaacgacgc cagccagggt ggcatgaata ccagttttta ataaggcaaa ccaaagcaac
    15841 acaccaacaa acatatacgg gcccgtgcgc ctaatgccac cgaaattcat cgccaccagc
    15901 aagaaggtta acgctcctac ccatgctgct gcagcaaaat ttaactgctc ggtatagaat
    15961 actgcaataa cagcaatcgc ccctaagtca tcaacaattg ccagcgccac caaaaatgtt
    16021 accaatgact taggaactgt attacccatc aaggtaataa tacccacagc gaaagctata
    16081 tctgttgcca tcggtatacc ccagcctccg gcaccaggtc caccaatatt aaaaacagca
    16141 tataaacctg ccggaatgac catgcctccg atagctgcca taatcggcag aactgctttc
    16201 ttagtatctg cgagctcacc aacgagaaac tcccgcttaa gttctagacc gaccagaagg
    16261 aagaaataag ccatcaagcc gtcattgatc cagtgctgca gagacagttt tagctcaaac
    16321 ccgccgaaag aaagcttaaa ataggtcttt aatatattct catagcccgc cgacaaaggg
    16381 gaattagcca acaacaaggc tacaactgcc atagtcatta gaatcaagcc acttgttgat
    16441 tgacgatgta taaattcgtc aaacggcgtc agtaccctgt cgaaagcctt ttcccatgga
    16501 gcataaaaca ccttgcccac attcttcgat ttttccttag caccaaacat gactctcctt
    16561 cagttttatt aagtcgtaaa aattgatggt atgcgtttcc acagcaatac caataagtac
    16621 aaatacgtaa cccacacctg cgcttgaata atatttcatg tttacatgac taaacaagtt
    16681 tctctgacac aaaaaagcgg ctatttgtag ccgcctattt acactccatg acctaacgat
    16741 cagttaagtg caaagcgaat cggcacttta accgagatga catccccctt tagagctatt
    16801 ggggcagcag gataactctc tacagaagac actgcggcca tagccgcctt atttaacaag
    16861 ctatatttgg ctgactgcac tctctctgca gataagcgct taccaaaacg atctaggcgc
    16921 acctcgacaa ccaccagccc ttctaagcca cgcttaatag cacgactcgg gtactgaacc
    16981 ttacgcaatg tttgcttgac aatacttgag cgataaagct tcaacatcat atcgtgctgc
    17041 tgctggataa tttcaggatc aatatcgaag tcatccccaa gctccaagtc gtcgacaagc
    17101 tcctcctcga ccgccacact ttcttcaaca agctctgcaa ccacctcctt ttcttcaacg
    17161 actatcgact gacttgctgg cttagtgctc tctatcttat cgggtactat ttctaacgta
    17221 gaggcggcat caacggcctc tgtcgttgcg tttgccaacc cccctaaaga agctgcagga
    17281 acttcgcccg aaccagcagc catcgcaagc tgctgcatcg cccccatcca ctgcactacg
    17341 atatcccgac gctcaggctg aacagttgta gcttcataca acgatagggc tccagcatta
    17401 tctacagccc ccaatattga ttgcttaaac tctgtagaag gcggtcgctt acctatccat
    17461 gtgttcagca gcatatcaaa actaccaatt cggtcatatg aggccgtctt gacaccatta
    17521 acatgtatca caatcttgcc atccgggctt tggtcaaaaa gcaaagtgtc tccacgcttc
    17581 aggctaaaac gggccatgtt attaaaagct ataaactcat cggaataacg gttcaacatt
    17641 gcctcttcat tattagcaac aatcaactga gtccactgac tcgagaaccg cctaggactc
    17701 cagcgcttgg ccgtgactcg aatttccatc attcgccgtg tactagcaag cgcctggacc
    17761 gcttctgctg tatttgcagg ctcttctaaa tacagcgcac caacaaaata agagcggttt
    17821 aactctttaa attcggccac tccgtttaac accatgcctt ctggtaacgt ctcagcaaca
    17881 gccataaaac tcattaattg actaaagaaa acaatcgtta ttattcgcat cacattcctg
    17941 cccactttca tccaatagca aattttttat tattagtagc tatcctgatg cttcaaggtg
    18001 tcattcttga tcaacttaca gcaccatcgt gccaccgaat agccctttat tatcactcta
    18061 cactagccta aaagcctaat aaagtcgtta gcattgagga gtatagcttt tttcgcctct
    18121 aacagcagtg cctttcaata aaagacaacg agaaataacc tcgggcagcc catacctacc
    18181 tgcttttata agctcccccc ccctctgcgt cgggctctgg cattgctttt caaaagacca
    18241 gcctctttgc tatattgaaa ctattacagc gacattgctg tctatccccg atactataac
    18301 tgtttgtacc gagcccttta tgatccgcat tactatattc tccctcattc tcctaatcac
    18361 agcttgcagc agccagccaa tgaagccaaa ggatattacc ggactatggc ttaaagccag
    18421 taaaaacggt gagcctgaag ggttctatct cgggcctcag ggagacttac agctatacaa
    18481 tatttttagc tggcttggcg agagttgggg tatcgaaggg aaatcattgc tttggctcac
    18541 agccaccgaa caagtcccct caccagagct cagcgagctc cattattcac taaaagggga
    18601 taacctaatc atttcagaag gctcctactt taatggtgag tatcaacggg ctgcagtaca
    18661 gatcctttgc gggagtgtaa atatattgca gcaagccgat gaccaacagc tctctatcac
    18721 actcatccaa gaagacaaaa aaagcacgat caatcaaaag cttatatcaa gaaaagttat
    18781 tgccaacccg gagacagcaa cccctttcac gcttgccatc gcttctgacc taatcaatga
    18841 caaacaaccc tatcgattac ttctcgtcct aagtgatgga cgtacgatta tcagtcgtca
    18901 aagtattgag tacacaaaac taccggggca atgtgtcgca ccaatcgacc tctagcctcg
    18961 ataaaagaac taactcaccc tatctcgagg ctatccatct tctctaacaa aaactcagcc
    19021 tcgagatctc ctgtcaacat aatcgtgtca tcagtcacta ataaaccgat cttcatttgt
    19081 cgtttaatcc ccccagtcaa agtcttcagt aaggcctcag gtagcaagta atattcacac
    19141 ttatctagta ctgacaattc agccccatgc tttgcccacc atacccgcga cgactcttga
    19201 taggaatagt tcgcataagt gtctgacttc cccctcaacc acatcatccg atcaacggat
    19261 ggacttccca cctctatcca caacttaacc tcgccagtat catctttcag ccataacggc
    19321 gcatcatcga cctccgacaa ccctcgacca aaggttaatt tctcatcggc gttaaggcca
    19381 aatacaataa ttcttgttaa catgcgcaat agagattcag aggggtgaca tgcaacagat
    19441 aaatgatgct cagcatagta gtgccggttc atatcggata cttgtaattg aattttgtag
    19501 accgtagatt taagcgccat tcactgctca cagagttgct atcagttaaa atgcccatat
    19561 taacactaag cgagacaaga ataatcaatg ccactcccac ccaggtgttt cagaccgtca
    19621 tcggtatcga tcattatcat cgctggaacc cttggctcaa agaggcgaaa ggctccgtca
    19681 aacctgggga tagcgtaaga gtcaaagtcg atcttggccg agacaagctg gaggagtata
    19741 accatacaat cctagcttac aaaacggaca aatactttgc ttgggaagac aagggctggt
    19801 tcacctttct aaccaagggc tcacgtcatc gctacttttc actgacagag gaaggcgcga
    19861 ctcattacag agttgagcta aacctctcag gtctatttgc aggccttgct cagcgtaagt
    19921 ttggcgctgc tttgtcgaag gggctagccg ccgaagcaga cgccctcaag aactattgcg
    19981 aagcaatgac gagcaattaa tttccttttt aactcaccac ctccttcgtc gccgcaacag
    20041 ataaactacg gtcaaataac ctccctctca acagcaattc tgataacgag agcacgatga
    20101 gtcccagtgc cccccacact gatagccact ccctattaga ggtcggcacg aatagcaacc
    20161 ataaaaaatc cgtactttac tcctggtcac tcttaacgat tacactcgtg gaaaaagaca
    20221 ctacgctgca gaacaagtaa ttcattgatg agtcaatacc actaacatta cccccccctt
    20281 taaaaagtgg tgtgaaacaa tgactaactc taaatatcct ttgttattct tagctcacgg
    20341 cagcccaatg aacgcaatcg aggacaaccc atttagcagg gattggcata aactctatat
    20401 tggcactcct tcacctaaag ccgtaatcgt catttctgca cactgggaga gcaacggcac
    20461 ttatatcacc caccacagaa gccctccaac actgcacgat tttagcggtt tccccgctca
    20521 actaaaccaa ctacggtacg cctgtcccgg tgcaccgata ctcgccgaag aggtacaccg
    20581 acgggtgccc tctattcagc tcgatcagca gcggggttta gatcatggtt gttggtctct
    20641 catgaatcaa ctttttcctc gcgccaacat acccacctta cagattagtt taaaccgtaa
    20701 acttagccca caacaacact gggacttagc aaaacagctt aaatggctta gacaagaaga
    20761 ggtgttaatt ttatgctcag gcaatatagt acacaatata gccgcttggc aggcttggat
    20821 gagcggaaat ataaatgatg ttacttgggc gggtagcttt gacaaaacga tatacaacgc
    20881 ccttaaaaat agcgatacgt catcactcat acactactca gaacactacg gcagcgagct
    20941 ttctgtgcca actgcagaac attatttacc actaatatat gctgacgcaa tacgtgacaa
    21001 gaaagacccg cttattagct ctaccccctc tatcaatagc ttcgaggcca gttgcagtcg
    21061 atcaatccga tttggctaaa ttttaattaa ggttatcgtt aagcatagca attaaatcca
    21121 ctgcccctcc ccctgcacac tttgctcgca cccgctccga gcaaagaagc gccatcgcct
    21181 gttcctcgct catagggcga ttaaataagt aaccttgctg cacaccacaa cctagactag
    21241 caagaaagcc agattgctgc tctgtttcaa ccccttccgc tactaaacta caatccaagt
    21301 ctttggccaa actaataatc gacttaataa tatgctcact acgactcgag cgataaatgt
    21361 ttttgacgaa gctgcgatct attttcacct catctaccgg taaactttgc aaatatgaca
    21421 acgacgaata acctgtacca aaatcatcga tggctactaa gacgccctgg ttatgcaaag
    21481 actgcaacgc ctcccttacc ggtaaatgct tgtcgattag gaggcgctcc gtcacctcga
    21541 gtgtgagaca atttgctggc agctctgtca actggagcag ctcactcaca tccttcaata
    21601 actgagggcg accaaactca gctgctgaga tattcactga aatcctaatc ggccgccgca
    21661 cccgctcaat ccaccgctgg caagcaatgc aagcctgttc caatacccaa cgatcgattg
    21721 cctttaacat accgttagac tcggccaaag gaataaattg atccggcatt actaaggtcc
    21781 catcacacct taaccaacga actaatgcct caaaccctac cacccgccca gtcaagacat
    21841 ccacctgagg ctgatagcgc aaagtgagct cattattctc tatagcagat ctcagcagat
    21901 taagctgcac taactcctct gccatatggt gctgtagacc actgacgtaa taccgataca
    21961 cattaccgcc tgaactttta gcctgactca atgctaaacc tgcattattt aacaactcac
    22021 tgctatctct acttgaattt ggatagtctg taatacctat actagcgctt atatagactg
    22081 tgtttccttt tataatataa ggctctgcta gcgaaagtaa aagtaatgaa gccagctcac
    22141 cgctatcagc tatagaatcg atattcccat gcagaatgac aaattcatct ccaccaaaac
    22201 gcccgcaatt ttcacctaca atgcctacaa ttctccccgc aactagttcg agcaataggt
    22261 ctccacattc atgcccaaag ctatcattca cttgcttaaa acggtctaat ccgacaaaca
    22321 acagactaaa ttgctgatga tgacgagcag aaaactgaat ctggctcgat aagacacgat
    22381 caaaagcact gcgactcatc gttcctgtta acgggtcttt ctctaatata cgacgcagct
    22441 ttttctcagc agagctcttt tctgccagtt catgcagggt gacgacaacg ccc
//
