LOCUS       c00136_NZ_JAJB..       10920 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JAJBNW010000072.1 Anaerosalibacter bizertensis strain MSK.14.19
            PBLBGLII_72, whole genome shotgun sequence.
ACCESSION   c00136_NZ_JAJB..
VERSION     c00136_NZ_JAJB..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 01:45:24
            Original ID  :: NZ_JAJBNW010000072.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10920
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10920
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[8209:10825]"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      8210..10825
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
     protocluster    1..10920
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4376:10825]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     (minimum(2, [ACD1_car, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     Butyrate_kinase, CT_Propionyl_CoA1, CT_Propionyl_CoA2,
                     CT_Propionyl_CoA3, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_2_CAF,
                     CoA_trans_6_Glutaconate, E1_dh, ECH_1, ECH_2, HBT, HBT_2,
                     HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C, Thiolase_N,
                     adh_short, adh_short_C2]) or FA_synthesis) and not
                     (Gly_radical_scatole or Gly_radical or Gly_430_pcre or
                     Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_fatty_acids"
                     /protocluster_number="2"
                     /tool="gutsmash"
     proto_core      4377..10825
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     (minimum(2, [ACD1_car, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     Butyrate_kinase, CT_Propionyl_CoA1, CT_Propionyl_CoA2,
                     CT_Propionyl_CoA3, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_2_CAF,
                     CoA_trans_6_Glutaconate, E1_dh, ECH_1, ECH_2, HBT, HBT_2,
                     HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C, Thiolase_N,
                     adh_short, adh_short_C2]) or FA_synthesis) and not
                     (Gly_radical_scatole or Gly_radical or Gly_430_pcre or
                     Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_fatty_acids"
                     /protocluster_number="2"
     cand_cluster    1..10920
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [PFOR_II, POR, POR_N]) and
                     (minimum(2, [ACD1_car, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     Butyrate_kinase, CT_Propionyl_CoA1, CT_Propionyl_CoA2,
                     CT_Propionyl_CoA3, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_2_CAF,
                     CoA_trans_6_Glutaconate, E1_dh, ECH_1, ECH_2, HBT, HBT_2,
                     HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C, Thiolase_N,
                     adh_short, adh_short_C2]) or FA_synthesis) and not
                     (Gly_radical_scatole or Gly_radical or Gly_430_pcre or
                     Gly_8-9_TMA))"
                     /detection_rules="(Fer4_7 and TPP_enzyme_C and POR and
                     POR_N and PFOR_II and not (EKR or Fer4_16))"
                     /kind="interleaved"
                     /product="OD_fatty_acids"
                     /product="porA"
                     /protoclusters="2"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10920
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="OD_fatty_acids"
                     /product="porA"
                     /region_number="1"
                     /rules="(minimum(1, [PFOR_II, POR, POR_N]) and (minimum(2,
                     [ACD1_car, ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (Gly_radical_scatole or Gly_radical or Gly_430_pcre or
                     Gly_8-9_TMA))"
                     /rules="(Fer4_7 and TPP_enzyme_C and POR and POR_N and
                     PFOR_II and not (EKR or Fer4_16))"
                     /tool="gutsmash"
     CDS             167..874
                     /locus_tag="ctg136_1"
                     /transl_table=11
                     /translation="LSTRLFIIAITPALVITVGLYLSDRYDKEPLKLLLITYILGALSV
                     IPTIFVEELLTVFNVFPGILGAFYTAFIVAGFTEEYFKRLVVLKVAYKSKYFNEKLDGI
                     VYAVFASMGFATIENVIYVVYRYSNNPYIGLYRGILSVPAHGVFAVTMGYYLSLAKFST
                     IEERKRRAYRRSLYMPIIFHGIFDFILMANIPQLTIIFVPYVIYLWWLNERKLSKYLYD
                     SRSRFIGTREKRK"
     CDS             943..2121
                     /locus_tag="ctg136_2"
                     /transl_table=11
                     /translation="MEKKTLRIIFFTTLICTSILLTSCVKLKAKPKDSEDVNESTKSKL
                     VETKPNATATILAAGDVMFHSPQIRGAYDETTGTYDFKENFKYIKKYVDSADLALANFE
                     TTTAGEERGFQGYPNFNSPEESIEALKDSGFDILSTANNHTLDQGKDGLLKTIDTIKKY
                     DLKNVGTYKEPEQHILIEKVNDIDIGILSYTYGCNGMEHTLTDEELKYMVNIIDEDKIK
                     NDIYKIKEKGADLVIMFIHWGNEYEMEPNEEQIELGKKMTEWGVDIVFGSHPHVIQKSE
                     IIQSNGEDKFIIYSLGNFLSNQRRESINNKYTEDGVMVNIEVEKDFSNNKTIIKNVEYI
                     PTWVNKYIESGKPKYEILPVEDFIDTEVFNQETLLKMKESYKNTMNKMGQQQ"
     CDS             2266..3114
                     /locus_tag="ctg136_3"
                     /transl_table=11
                     /translation="VCETLQYLKELFLNVRIRDIIDILIVAFAFYKLFMLIRETRAEQL
                     TKGIIVLFVATKISEWLELFTVYWILEKTMTVGVLAILIVFQPELRRGLEYIGRSRFFT
                     KSFAEIKDESLNEVVDEIVDAVASLSRQKIGALIVMERETGLSEVVETGTRIDGKISSG
                     LLINVFIPNTPLHDGAVVIKENIVKAAGCFLPLTDNTSLSKELGTRHRAALGISEKSDC
                     LAIVVSEETGAISIAENGSLARYLDTKTLKQILIDMYKPKIQRQSFFVKWRRKDEQGEE
                     K"
     CDS             3092..4372
                     /locus_tag="ctg136_4"
                     /transl_table=11
                     /translation="MSKEKKSNLTIKIFSLVIAIILWSYVMSEVNPKITKEFRNIDVVF
                     SNMEDLERSGIELMSPKEVKINVKVEGRRSEVLKLRDTDIIAKVDLSGYSEGTKKVPIY
                     IDVPSKVDIVDYTPKEISFRFERIVSKEKPVVLKTIGKLEPGYSLGDGEIKPQSVILKG
                     PKSWVNSVREVVAVVDITGKTKDINATVPIKLLDDDGNDVGRVEKEPNVVDVFIPMYRS
                     RKIPIDIQLDGSIPTEYENPTLTVSPKAVDVKGNDAILNTLSSIKTKPISVYKLVGSGS
                     VETELLLPEGIELVDPNQKIVVSLKSNSIENGTDVEDSDVENGNISENINKRFDYSFSE
                     INVRNLGDELVIDTSNSTNSITVILNGPKDYLNSTGKEVLSPEIDLKGLDEGVHEVKLI
                     IKDIREIKVSDIIPAKVKVSLKREEKE"
     CDS             4377..5462
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_fatty_acids: Butyrate_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg136_5"
                     /sec_met_domain="Butyrate_kinase (E-value: 3.2e-135,
                     bitscore: 440.0, seeds: 62, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRKYVLVINPGSTSTKVAIYEAEKEIKSNKITHQLKDLEKYARV
                     YEQYDYRLKLIYDWLAKEEISTSSLVAVVGRGGLLRSIPGGTYIVTEKMIEDLKIGIQG
                     EHASNLGGILAKGIADKEGIKSYIVDPVAVDEFKDIARISGLKEIKRKSLIHALNIKAV
                     SYRRAKELNKDLSELNLIVAHLGGGISIAPVKKGKMIDVNNASEMGPFSPDRTGSLPVG
                     DIVKLCYSGKYTHEEMKIKLKGKGGLSGYLGTMDAREIEAMIAQGNKKADLIYSAMAYQ
                     IGKEIGSVATVLEGNVDNIILTGGLAYSKYLTDFIIGMVEFIADVVIYPGEDEMDALNK
                     GVLRVLNKEEKEKIYENEVDL"
     CDS             5462..6385
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTA_PTB"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg136_6"
                     /sec_met_domain="PTA_PTB (E-value: 4.8e-52, bitscore:
                     166.8, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKNFQELLDLAKERDPKKIAVAVAEDREVLTSVKAAKDLGVADS
                     ILVGDKNKIEKIAKDIKMDLSQFEIIDEKDTVEACRKAVSLVSSKKAHVLMKGLIDTAV
                     IMKQVLDKEIGLRTGNLISHLAVFSVSTYEKLIIVTDAAMNIHPNLSQKRQIIENAVSF
                     AHSLEMEKPKVAVICAREKVTPNMEATIHARELEDMNKRGDITGCIIEGPLALDNAISK
                     EAAKHKGIDGPVAGDADVLIVPNIETGNVLYKSLTFFAKAESAGLIVGTSAPIVLTSRA
                     DTAEAKLRSIVLGVLMASKSGHTYGL"
     CDS             6417..7490
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_fatty_acids: Butyrate_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg136_7"
                     /sec_met_domain="Butyrate_kinase (E-value: 2.4e-168,
                     bitscore: 548.7, seeds: 62, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEKYRILVINPGSTSTKIAVFDDEKAIFEETLRHSTEELSKYDK
                     VYDQYKFRKDIILEILNKNNIELESLNAIVGRGGLLNPIEGGTYKVNEKMLKDLKIGVQ
                     GEHASNLGGIIANEIAKMIDKPAYIVDPVVVDEMEDIARISGMPEIERRSIVHALNQKA
                     VARRHSKSKNKNYEDINLIVAHLGGGISVGAHRKGKIIDVNNALDGEGPFSPERSGGLP
                     VGDLVKLCYSGKYSEDEMKKKIKGNGGLVSYLNTNDAREVGEMIKEGNKEAELVYNAMA
                     YQIAKEIGSCAAVLKGEVDGIILTGGIAYDKEFTKWIEEMVKFISNVYIYPGEDELMAL
                     AEGGLRVLRGEEKAKEY"
     CDS             7509..8183
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CbiA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg136_8"
                     /sec_met_domain="CbiA (E-value: 4.7e-10, bitscore: 29.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYRDKRIRIIVGHYGSGKTEFSVNYALKIAEQGKKVALVDLDIVN
                     LYFRSREKEKVLEKSNVKVISSSIKASAVDIPAISAEAYAPLQNEKYDTILDIGGDPVG
                     ARVLGRYNDILKEGSYDMFYVLNANRPETNTLDKAIGYLNAIEGASRKKVTGIINNTHM
                     LKSTTVDDVLKGQKLAKELSQKLEIPIKYIVALESVAEKLPNNLEGEIFPINLYMREDW
                     ML"
     CDS             8210..8437
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg136_9"
                     /sec_met_domain="Fer4_7 (E-value: 1.4e-15, bitscore: 47.4,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.2e-08, bitscore: 24.3,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.2e-07, bitscore: 20.1,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKVKGRVTFQENLCKGCGLCVSVCPMKIISLDKEKINEKGYHPA
                     TVKEMDKCIGCTNCATMCPDVVITVERITE"
     CDS             8458..9534
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg136_10"
                     /sec_met_domain="PFOR_II (E-value: 2e-28, bitscore: 88.5,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 1e-56, bitscore: 181.9,
                     seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKILMKGNEAIGAAAIEAGCKYFFGYPITPQSELPEYMAREMPK
                     INGVFLQAESEIAAINMVYGAAGAGARVMTSSSSPGISLKQEGISYIAGAELPCLIVNI
                     MRGGPGLGSIQPSQTDYFQATRGGGNGDYRLVVLAPANVQELVDLIIEGFDIADQYRNP
                     VMILGDGMIGQMMEPVEFKKPKKRELPEKDWATTGTKGKRKPNIINSLYLAAEELEEHN
                     ERLQKKYKAIKENEVKVESYNIEDADIVVAAYGTTSRIAKTAISQLEKEGYKVGLIRPI
                     SLWPFPYDEFNKINDKCKGVLTIEMNTGQMVDDVKIAVNGRFPVYFYGRTGGMVPTPNE
                     IAEKVKESMEVKSNGCSI"
     CDS             9518..10264
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg136_11"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.6e-28, bitscore:
                     87.3, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVVFEKTRGLTDEQTHYCPGCTHGIVHRLVAESLEELGVLDDTI
                     GVAPVGCSVLAYKYFNCDMHEAAHGRAPAVATGIKRVHPDKFVFTYQGDGDLASIGTAE
                     IVHAAHRGEKISTIFINNAIYGMTGGQMAPTTLVGQKATTAPYGRDEAHAGRPIRMAEM
                     LATIHGAKFVERVAVNTPANVRKAKKAIKKCFETQINGEGFGIVEVLSTCPTNWGYTPE
                     EALKWLEENMIPYYPLGNFRTPEEVE"
     CDS             10268..10825
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg136_12"
                     /sec_met_domain="POR (E-value: 2.6e-39, bitscore: 124.8,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEERIVVAGFGGQGVMAIGQLLTYAGMIENRHVSWLPSYGPEMRG
                     GTANCNVIVSDESIGAPVIEEASAVIVMNKPSLDKFEDDVIKGGKLFINSSLIDKKAVR
                     NDIDVYYIPANEIANKLGNDRVANMVILGAYLEATKLVKEESVLEAFTKVFGENKAHLL
                     PLNKEAIEKGMEAAKEQEKAMV"
ORIGIN
        1 gaaaaaataa atgttagggt aaattatttt ccaccccaac atttattata gaacctttct
       61 tatttaatac ctatttaata cctattataa aggctataaa atcagaaaca taggcaataa
      121 taatattaat gtatagaata aattaaaata atttgggggt gctattttgt caactagatt
      181 atttataatt gcaataacac cagcattagt tataacagta ggtctttatt taagtgatag
      241 atacgataaa gaaccactaa aattgttatt aattacttat attcttggag cattgtctgt
      301 aatacctact atatttgtag aagaattatt aactgtattt aacgtttttc ctggtatact
      361 tggagctttt tatacagctt ttatagtagc aggatttaca gaggaatatt ttaaaagatt
      421 ggttgtttta aaagttgctt ataaatcaaa gtattttaat gagaaattag atggtatagt
      481 ttatgctgta tttgcctcta tgggatttgc tacaatagaa aatgttatat atgtagtata
      541 tagatacagc aataaccctt atattggcct ttatagaggt atactatctg ttccagctca
      601 tggagtattc gcagttacaa tgggatatta tttatcttta gctaaattta gtactataga
      661 ggaaagaaaa agaagagctt atagacgttc actatatatg ccaataatat ttcatggaat
      721 atttgacttt atactaatgg ccaatatacc gcagttaaca attatatttg ttccatatgt
      781 aatatattta tggtggttaa atgagaggaa attaagtaaa tacttatatg attctagatc
      841 aagatttata ggaactaggg agaaaagaaa gtaaaaaatc attgaaaaaa ttattatata
      901 gaagtaatat atagttatcc catataaaaa aggagagaga acatggaaaa gaagaccctc
      961 agaatcatat tttttacaac tttaatttgt acttccattt tattaacatc ttgtgttaaa
     1021 ttaaaagcca agcctaaaga ctctgaagat gttaatgaat ctactaaatc taagttagta
     1081 gaaactaaac caaatgctac tgctactata ttggcagcag gagatgtaat gtttcattca
     1141 cctcagatta gaggagctta tgatgaaaca acaggtactt atgatttcaa agaaaatttt
     1201 aaatatataa aaaaatatgt agattctgca gacttggctt tagcaaattt tgaaactact
     1261 actgcaggtg aagaaagagg gtttcaagga tatccaaatt tcaactctcc agaagagtct
     1321 atagaagcat taaaagattc aggatttgat atactgtcta cagcaaataa ccatacttta
     1381 gatcaaggaa aagatgggct tttaaaaact atagatacaa taaaaaaata tgaccttaaa
     1441 aatgttggca catataagga accagagcag catatactta ttgaaaaagt aaatgatata
     1501 gatattggaa tactatccta tacctatgga tgtaatggta tggaacatac tttgacagat
     1561 gaagaattaa agtatatggt aaatataata gatgaagata aaataaaaaa tgatatatat
     1621 aaaataaaag aaaaaggagc agatctagtt attatgttta ttcattgggg aaatgaatat
     1681 gaaatggaac ctaatgaaga acaaatagaa ttagggaaaa aaatgacaga gtggggagta
     1741 gatatagtat ttgggagtca tcctcatgtg attcaaaagt ctgaaataat acaatctaat
     1801 ggagaagata agtttataat ttattccctg ggaaatttcc tgtcgaatca gagaagagaa
     1861 agtataaata ataaatatac agaagatgga gttatggtaa atatagaagt agaaaaagat
     1921 ttttctaata acaaaactat tataaagaat gtggaatata ttcctacctg ggtaaataag
     1981 tatattgaaa gtgggaagcc taaatatgaa atacttccag ttgaagattt tatagataca
     2041 gaagtattta atcaagaaac cttacttaaa atgaaagaat cttataaaaa tactatgaat
     2101 aaaatgggcc agcagcaata atttctggct tatttttatt aacaaaaagt aatttatttg
     2161 ttaacttttg ttattaataa gtctttttat tgatatagat ttaaatttac aataatttat
     2221 tatataatag aattatagaa tattatgtga atatagtata taagggtgtg tgaaaccttg
     2281 caatatttaa aagaactttt tctaaatgta agaattaggg atattataga catacttata
     2341 gtagcctttg ctttttataa attatttatg cttataaggg aaacacgagc agagcaactt
     2401 actaaaggaa ttatagtttt atttgtcgct actaagataa gtgagtggtt agaattattt
     2461 actgtgtatt ggatattgga aaaaactatg actgttggag ttttagctat tcttattgtt
     2521 tttcaacctg aattaagaag aggattagaa tacattggta gaagcagatt ttttactaaa
     2581 tcttttgcag aaataaaaga tgagagctta aatgaagtag tggatgaaat agtggacgca
     2641 gtagcttcgc tgtcgagaca aaaaattgga gcattgatag ttatggagag agaaactggc
     2701 ctaagtgaag ttgtagaaac tggaactaga atagatggta aaatttcaag tggtctactt
     2761 ataaatgttt ttatacctaa tactcctctt catgatggtg cagtagtaat aaaagagaat
     2821 attgtcaaag cagcaggttg ttttttacct ttaacagata acacatcttt aagtaaagaa
     2881 ttaggtacca gacatagagc agcgctaggt atatcagaaa agtcagattg tttagctatt
     2941 gtagtttcag aagaaacagg cgcaatatca atagcggaaa atggaagtct agcaaggtat
     3001 ttggatacaa agacattgaa acaaatactt attgatatgt ataaacccaa aattcaacga
     3061 caaagttttt ttgtaaagtg gaggcgtaaa gatgagcaag gagaagaaaa gtaatctcac
     3121 tataaaaatc ttttctctag taattgctat tatattatgg agttatgtaa tgagcgaagt
     3181 taatcctaaa ataactaagg aatttagaaa tattgatgtt gtattttcta atatggaaga
     3241 tttagaacgt tcaggcattg aactcatgtc tccaaaagag gtcaaaataa atgtaaaggt
     3301 tgaaggtagg agaagtgaag ttttaaaact tagagatact gatataatag caaaagtaga
     3361 tttaagtgga tattctgagg gtactaagaa agtacctata tatatagatg taccaagtaa
     3421 agtggatatt gttgattata ctccaaaaga gatttctttt agattcgaga ggattgtatc
     3481 taaagaaaag ccagttgtgt taaaaactat aggtaaactc gaaccagggt atagtttagg
     3541 agatggagaa ataaaacctc aatctgtaat attaaaagga cctaaaagtt gggtaaattc
     3601 agtcagggag gttgtggctg tagtggatat aacaggtaaa actaaggata taaatgctac
     3661 agtacctatt aagcttttag atgatgatgg aaatgatgta ggaagggtgg agaaagagcc
     3721 taatgttgtg gatgtcttta ttcctatgta taggagcagg aaaattccta ttgatattca
     3781 attagatgga agtattccaa ctgaatatga aaaccctaca ttgactgttt cgcctaaggc
     3841 ggtggatgta aagggtaatg atgctatttt gaacactcta tcatctataa aaacaaaacc
     3901 gattagtgta tataaacttg taggaagtgg gtccgtagag actgaattat tgttacctga
     3961 aggtatagaa ttagttgatc caaatcaaaa gatagttgta agtttaaaat cgaatagtat
     4021 cgaaaatgga acagatgttg aagattctga tgtagaaaat ggaaatatta gtgaaaacat
     4081 aaataaaaga tttgactata gtttttctga aataaatgtt agaaatttag gagatgaact
     4141 ggttattgat accagtaatt ctactaatag tataacggtt attctaaatg gtcccaaaga
     4201 ttatttaaat tcaacaggaa aagaagtttt atcgccagaa attgatttaa agggattaga
     4261 tgagggagtt catgaagtaa aattaatcat aaaagatatt agagaaataa aagtatcaga
     4321 tattattcct gctaaagtaa aagtttcatt aaaaagggaa gaaaaggagt gaaggcatga
     4381 ctagaaagta tgtattagtc attaacccag gctctacttc taccaaggta gcaatatatg
     4441 aagctgagaa agagattaaa tccaataaaa ttacgcacca actgaaagac ctagaaaaat
     4501 atgcaagagt atatgaacaa tatgattata ggttgaaatt aatttatgac tggttagcta
     4561 aggaagaaat ctccacttct tctttagttg cagtagttgg tagaggaggg cttctaaggt
     4621 ctataccagg aggcacttat attgtaacag aaaaaatgat agaggattta aaaattggta
     4681 ttcaaggtga acatgcttca aatctaggtg gcatactggc aaaaggtatt gcagacaaag
     4741 aaggaatcaa atcttatata gtggatccag tagctgtaga tgaatttaag gatatagcta
     4801 ggatttcagg tcttaaagaa ataaaaagaa agtcactaat ccatgcatta aatattaaag
     4861 cagtttccta tcgaagagca aaagaattaa ataaagattt aagtgaatta aatttaatag
     4921 ttgcccattt aggagggggt atatctatag ctcctgttaa aaaaggaaaa atgatagatg
     4981 ttaataatgc tagtgaaatg ggaccttttt ctcctgatag gacaggaagc ctcccagttg
     5041 gggatatagt gaaactttgt tattcaggaa aatatactca tgaagaaatg aaaataaaat
     5101 taaaaggaaa aggtggatta tcaggttatc tggggactat ggatgctaga gaaatagagg
     5161 caatgatagc ccaaggcaat aaaaaagcag accttattta tagcgctatg gcatatcaaa
     5221 taggcaaaga aattggctct gtagcaacag ttttggaggg aaatgtggac aatataattt
     5281 taacaggtgg actagcttat tcaaagtatt taacagattt tataattgga atggtagaat
     5341 ttattgcaga tgtagtaata tatcctggag aagatgaaat ggatgcctta aataaagggg
     5401 tacttagagt gcttaataag gaggaaaaag aaaaaatata tgaaaatgag gtggatttat
     5461 aatggttaag aatttccagg agttattaga tttggctaag gagagggatc caaaaaaaat
     5521 tgctgtagca gttgctgaag atagagaggt acttacttct gtaaaagcag ctaaagatct
     5581 aggtgttgca gattctattc ttgttggaga taaaaataaa attgaaaaga tagcaaaaga
     5641 tataaaaatg gatctttctc aatttgaaat tatagatgaa aaggatacag ttgaagcttg
     5701 tagaaaagct gtaagtttag ttagttcaaa aaaagcccat gttttgatga aaggtttaat
     5761 agatactgca gttataatga agcaagtact agataaggaa ataggcctta gaacaggaaa
     5821 tttaataagc catttagctg tgtttagtgt ctctacatat gaaaagttga ttattgttac
     5881 agatgcagct atgaatatcc atccgaattt aagtcagaag agacaaataa ttgaaaacgc
     5941 agtgtctttt gctcatagtc tagaaatgga aaaaccaaaa gtagctgtaa tctgtgcaag
     6001 ggaaaaggtt accccaaata tggaagctac aattcatgca agagaattag aagatatgaa
     6061 taaaagaggt gatattacag gttgtattat tgaggggcca ttagccttag ataatgctat
     6121 atctaaagaa gcagcaaaac ataaaggtat agatggacct gttgcaggag atgccgatgt
     6181 attaattgtg cctaatatag aaacaggtaa tgtgctttat aaatctttaa ctttctttgc
     6241 aaaagctgaa agtgcagggt taatagttgg aacatcagct ccaatagtat taacttctag
     6301 agctgataca gcagaagcta agctacgttc tattgtatta ggcgtactta tggcatctaa
     6361 gtcaggtcat acttatggcc tctaaaaaca cacaaaaatt agagaggaga cttaaaatgg
     6421 aagagaagta taggatatta gtaataaatc caggtagtac atctacaaag attgctgtat
     6481 ttgatgatga aaaagctata tttgaggaaa cacttagaca ttctacagaa gaattatcta
     6541 aatatgataa agtgtatgat caatataaat ttagaaaaga tataatactt gagattttga
     6601 ataaaaataa tatagaatta gaatctctaa atgcaatagt aggtagagga ggattgttaa
     6661 atcctataga aggtggtact tataaagtta atgagaaaat gttaaaagat ttaaaaattg
     6721 gtgttcaagg agaacatgct tcgaatttag gtggaataat agctaatgaa atagctaaaa
     6781 tgatagacaa acctgcttat atagtagatc cagtagttgt agacgagatg gaggatatag
     6841 ctagaatatc aggtatgcct gaaatagaga gaagaagtat tgtacatgca ttaaatcaaa
     6901 aggctgttgc aagaagacat tctaagtcta aaaacaaaaa ttatgaagac ataaatttaa
     6961 tagttgcaca tttaggtgga ggtatatctg taggagctca tagaaaagga aagattatag
     7021 atgtaaataa tgctcttgat ggagaaggac ctttttcacc agaaaggtct gggggacttc
     7081 cagttgggga tctagtgaaa ctttgttatt caggtaaata ttcagaagat gaaatgaaaa
     7141 agaaaataaa aggaaatggt ggactagtat cttatttaaa tactaatgat gcaagagaag
     7201 ttggagaaat gataaaagaa ggtaataaag aggcagaact tgtttacaat gctatggctt
     7261 atcaaatagc taaagaaata ggtagctgtg ctgctgtact taaaggtgaa gtagatggca
     7321 taatacttac aggtggaata gcttatgata aagagtttac taaatggata gaagaaatgg
     7381 ttaaatttat atctaatgta tatatttatc ctggagaaga tgagttaatg gctttagcag
     7441 aaggtggttt aagggtttta agaggagaag aaaaagcaaa agaatactaa ataggataag
     7501 gtgggaatat gtatagagat aaaaggataa gaattattgt tggtcattat ggtagtggta
     7561 aaacagaatt tagtgttaat tatgctttaa aaatagctga gcaaggaaaa aaagtggcac
     7621 ttgtagattt agatatagta aatttatatt ttagaagtag agaaaaagaa aaggtgttgg
     7681 aaaaatccaa tgtgaaagta atttcaagtt caataaaagc ttctgcagta gatataccag
     7741 ctatatctgc agaagcttat gccccactac aaaatgaaaa atatgataca attctagata
     7801 tagggggaga tcctgtagga gctagggttt taggaagata taatgatatt ttaaaagaag
     7861 gaagctatga tatgttttat gttctaaatg ccaatagacc tgaaaccaat actctagata
     7921 aggcaatagg gtatttaaat gctatagaag gtgcttcaag aaaaaaggta acaggaatca
     7981 taaacaatac acatatgctt aaaagtacta ctgtagatga cgtattaaaa ggtcagaaat
     8041 tggcaaaaga actttcacaa aagttagaaa tacctattaa atatatagtt gcactagaaa
     8101 gtgtagcaga aaaacttcca aataatttgg aaggagaaat tttcccaatt aatttatata
     8161 tgagggaaga ttggatgctt taattaatta tgagtaagga ggggtcaata tgcctaaagt
     8221 taaaggaagg gttacatttc aggaaaacct ttgcaaagga tgtggactat gcgtatctgt
     8281 atgtccaatg aaaatcatat ccttagataa agaaaaaata aatgaaaaag gatatcatcc
     8341 agcaacagta aaagaaatgg acaaatgtat tggttgtaca aattgtgcaa ctatgtgtcc
     8401 agatgtagtt attacagttg aaaggattac tgaataaaaa taaggagggt ttataacatg
     8461 gctaaaattc tcatgaaggg aaatgaggct attggagctg ctgcaattga agctggctgt
     8521 aagtactttt ttgggtaccc gataactcct caaagtgaac tccctgaata tatggcaaga
     8581 gaaatgccta agattaacgg ggtattttta caagcagaaa gtgaaattgc tgctataaat
     8641 atggtatatg gagcagcagg agcaggtgca agagtaatga cttcctcatc aagccctggt
     8701 atttcattaa agcaagaagg tatttcttat atagcaggtg ctgagctacc atgtttaata
     8761 gtaaatataa tgagaggtgg tccaggccta ggaagtattc aaccttctca aacagattat
     8821 ttccaagcaa caagaggagg gggaaatgga gattacagat tagtagttct tgctccagca
     8881 aatgtacaag aactagtaga tttaataata gaaggatttg atatagcaga tcagtatagg
     8941 aatccagtaa tgattcttgg agatggaatg attggacaaa tgatggagcc tgttgaattt
     9001 aagaagccta aaaagagaga actaccagaa aaagattggg ctacaacagg gacaaaagga
     9061 aagagaaaac ctaatattat taactctctt tatttagcag cagaagagtt agaagagcat
     9121 aatgagagac ttcaaaaaaa atataaagct attaaagaaa atgaagtaaa agttgaatct
     9181 tacaacattg aagatgcaga tatagtagtt gcagcttatg gaacaacttc tagaatagct
     9241 aaaactgcaa tttctcaatt agaaaaagaa ggatataaag taggacttat aagaccaata
     9301 tctttatggc ctttcccata tgatgaattc aataaaataa atgataagtg caagggtgta
     9361 ttgactatag aaatgaatac tggccaaatg gtagacgacg taaaaattgc agtaaatggc
     9421 agatttccgg tttactttta tggaagaacg ggtgggatgg ttcctacacc taatgaaata
     9481 gctgaaaagg taaaagaatc tatggaggtg aaaagtaatg gctgtagtat ttgagaagac
     9541 tagagggtta acagatgaac aaacccacta ttgtccagga tgtacccatg gtatagttca
     9601 tagattagtt gctgaatctt tggaagagtt aggagttctt gatgatacta taggggttgc
     9661 acctgtagga tgttctgttc tagcatataa atattttaat tgcgatatgc atgaggcagc
     9721 tcatggaagg gcacctgcag tagctacggg aataaaaagg gttcatccag ataaatttgt
     9781 atttacctat caaggagatg gggatttagc ttcaataggt actgctgaaa tagttcatgc
     9841 tgcccatcgt ggagaaaaaa tttcaactat atttataaat aatgcaatat atggtatgac
     9901 tggaggacag atggctccaa caacccttgt aggacaaaaa gctacaacag caccttatgg
     9961 aagagatgaa gctcatgctg gtagacctat aagaatggct gaaatgcttg ctacaattca
    10021 tggagcaaag tttgtagaaa gggtagcagt aaatactcca gctaatgtaa gaaaggcaaa
    10081 aaaagctata aaaaaatgtt ttgaaacaca aattaatgga gaaggatttg gaatagtaga
    10141 agtactatct acttgtccaa ctaattgggg atatactcca gaagaagctt tgaaatggtt
    10201 agaagaaaac atgatacctt attatcctct aggaaatttt agaaccccag aggaggtgga
    10261 ataagaaatg gaagaaagaa tagttgttgc aggttttggt gggcaaggag ttatggctat
    10321 aggtcaattg ttaacttatg ctggaatgat tgaaaataga catgtatcat ggctaccatc
    10381 ttatgggcca gaaatgcgtg gagggactgc taactgtaac gttatagtat ctgatgaatc
    10441 tataggagca ccagtaatag aagaagcaag tgcagtaatt gttatgaaca aaccatctct
    10501 tgataaattt gaagatgatg taataaaagg tggaaaactt tttattaatt catctttaat
    10561 agataagaaa gcagtaagaa atgatataga tgtatattat ataccagcta atgaaatagc
    10621 aaacaaatta gggaatgata gggttgcaaa tatggtaata ttaggagctt atttagaagc
    10681 tactaaattg gtaaaagaag aatctgtatt agaagctttt actaaagtgt ttggggaaaa
    10741 taaagcccat ctattacctt taaacaaaga ggctattgaa aaaggtatgg aagcagcaaa
    10801 agaacaagag aaagcaatgg tataaatgta caaaaagcta gctgaatttc agctagcttt
    10861 tttatttgtg tgcccagcat gatcaacaac ttggtggtga aagtccacta cgggcttggt
//
