LOCUS       c00110_NZ_JAJB..       15846 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JAJBNW010000049.1 Anaerosalibacter bizertensis strain MSK.14.19
            PBLBGLII_49, whole genome shotgun sequence.
ACCESSION   c00110_NZ_JAJB..
VERSION     c00110_NZ_JAJB..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 01:45:24
            Original ID  :: NZ_JAJBNW010000049.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15846
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15846
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[112:6078]"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [ACP_syn_III, ACP_syn_III_C,
                     FA_synthesis, GRDA, GRDB]) and Glycine_reductase and not
                     Pro_racemase)"
                     /neighbourhood="10000"
                     /product="Glycine_reductase"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      113..6078
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(3, [ACP_syn_III, ACP_syn_III_C,
                     FA_synthesis, GRDA, GRDB]) and Glycine_reductase and not
                     Pro_racemase)"
                     /neighbourhood="10000"
                     /product="Glycine_reductase"
                     /protocluster_number="1"
     cand_cluster    1..15846
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(3, [ACP_syn_III, ACP_syn_III_C,
                     FA_synthesis, GRDA, GRDB]) and Glycine_reductase and not
                     Pro_racemase)"
                     /kind="single"
                     /product="Glycine_reductase"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15846
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Glycine_reductase"
                     /region_number="1"
                     /rules="(minimum(3, [ACP_syn_III, ACP_syn_III_C,
                     FA_synthesis, GRDA, GRDB]) and Glycine_reductase and not
                     Pro_racemase)"
                     /tool="gutsmash"
     CDS             complement(113..1294)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_reductase: FA_synthesis"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg110_1"
                     /sec_met_domain="FA_synthesis (E-value: 6.3e-69, bitscore:
                     222.6, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDNNVKSMVGKVFNDIADALETGQFGRKIRVGITTLGSEHGVEN
                     VVKGAEIAQERDSNIEVVLIGPKVDSSLTQVVAKTEDEGYKKMEELLDNNEIDSAVTMH
                     YSFPIGVSTVGRVITPGKGKEMFIATTTGTSSPHRVEAMVMNGIYGIITAKAMGIDNPT
                     VGILNVDGAIQVERALKELDKNGYKINFTESLRADGGCVMRGNDLLSGVPDVMITDTLT
                     GNILIKMFSSYTTGGNYESLGYGYGPGIGEGYERTILILSRASGVPVVANAISYGASLS
                     KGNINEVAKEEFKKVNSAGFKEMLEGITKDSKKGTVDEEIIPPEKETVTGTISGIDIME
                     LEDAVKVLWKNGIYAESGMGCTGPVLMVNEGKVENAISILAKEGYISNESNIC"
     CDS             complement(1305..2843)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_reductase: ACP_syn_III"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg110_2"
                     /sec_met_domain="ACP_syn_III (E-value: 1.6e-08, bitscore:
                     24.6, seeds: 136, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAHAVVKGSGYVLIHTPDMILHNGTTQTTEKTINPNSDYLKNLPE
                     HIRSFEEVVSYPPNQTYIGNITPEELKEYKMPWHDKKVEGADKVGKFGEIMPQDEFIGL
                     MKIVDTFDLVKLEKKFTEDVKQKLGTHHFMKEDLILRLKEGEEIESIKKSVEEQGAEGL
                     YNNGELVGCVKRAHDIDVNLSAHVLFENLVAKASGVLAALNLIEKNNINPEEVEYIIEC
                     SEEACGDMNQRGGGNFAKAVGEMAGFTNATGSDTRGFCAAPTHAMIEAAALVDAKIFKN
                     VVVVAGGSTAKLGMNGKDHIKKGLPVLEDVVGGFAIIIGENDGVNPILRTDLVGRHTVG
                     TGSSPQAVISSLVTEPLDKGDLKITDIDKYSVEMQNPDITKPAGAGDVPKANYKMIGAL
                     GVMRKELERTQLNDFIETHGMEGWAPTQGHIPSGVPYVGFAREDILNNKIKNAMIIGKG
                     SLFLGRMTNLFDGVSIVMEKNPGKVDEEKGVSEEEIRSLVAEAMRDFASHLLKE"
     CDS             complement(2938..3171)
                     /locus_tag="ctg110_3"
                     /transl_table=11
                     /translation="MVKEIERAGIPVVHMCTVTPISMTVGANRIVPTIAIPHPLGNPNL
                     DFEEEKSIRRKLIERALKALTTEVEEQTIFEE"
     CDS             complement(3199..4248)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_reductase: GRDB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg110_4"
                     /sec_met_domain="GRDB (E-value: 3.6e-184, bitscore: 601.9,
                     seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKIKAVHYINQFFAGIGGEEKADYKPEVREGIVGPGMAINAGFK
                     GEAEIVATIICGDSYFNENIEEAKSEIVEMVKKYDPDIFIAGPAFNAGRYGVACGTITD
                     AVHKELGIPVLTGMYVENPGADMFKKSVYIVSTKNSAAGMRNAVKQMVPLALKLAKGED
                     IGSPEEEGYIARGVRKNYFAEKRGSERAVDMLLKKLRGEEFVTEFPMPDFDRVEPEAAI
                     KDLSKAKIALVTSGGIVPKGNPDHIESSSASKYGKYDIEGIDNLTKETHETAHGGYDPV
                     YANEDPDRVLPVDVLRDLEKEGKIGSLHRYFYTTVGNGTAVASAKAFAEEIAKELLSDG
                     VNAVILTST"
     CDS             complement(4282..4611)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_reductase: GRDA"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg110_5"
                     /sec_met_domain="GRDA (E-value: 3e-56, bitscore: 179.5,
                     seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLENQKRVKEAAEKYGEENVIVLIGGAEAEAAGLAAETVTAGDP
                     TFAGPLAGVQLGLRVYHVVEPEFKEAVDPDVYDEQIGMMEMVLDVDEIIEEVKGIRDEF
                     CKFND"
     CDS             complement(4627..4758)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_reductase: GRDA"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg110_6"
                     /sec_met_domain="GRDA (E-value: 7e-22, bitscore: 68.0,
                     seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLFDGKKIIIIGDRDGIPGPAIEECIKTTGGEVVFSSTECFV"
     CDS             complement(4792..6078)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_reductase: Glycine_reductase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg110_7"
                     /sec_met_domain="Glycine_reductase (E-value: 3e-234,
                     bitscore: 766.9, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLELGYLFIEDVQFAEETKLENKTLYVNKNELVNLIKEDEHFEK
                     VDLELARPGESIRITPVKDVIEPRVKVEGPGGIFPGMISKVDTVGSGKTNVLKGCAVVT
                     AGKIVGFQEGIIDMTGPGADYTPFSKLNNIVLVCEPKEGLKQHEHERALRMAGFKAATY
                     LGEVAKNLTPDEVEIFETEPMLESINKYPELPKVAYVQMLQSQGLLHDTYVYGVDAKES
                     LPTIIYPTEIMDGAIVSGNCVSACDKNTTYHHLNNPVVKDLFAKHGKELNFIGVIITNE
                     NVYLADKERSSNWTAKLAEFLGLDGVLISQEGFGNPDTDLIMNCKKIEQKGIKTVIITD
                     EYAGRDGASQSLADADPLANAVVTGGNANEVITLPPMDKIIGDTSYVDTIAGGFDGSLK
                     EDGSIVVELQAITGATNELGFNKLTAKGY"
     CDS             complement(6145..6462)
                     /locus_tag="ctg110_8"
                     /transl_table=11
                     /translation="MLEVDKKTFEEEVLKADGYVLVDFWSQGCEPCKALMPHIEELEKQ
                     YGDKMKFCKLDTMKARRLAISQKVLGLPVIAIYKDGEKIDERVKEEATEKSVEEMIKKY
                     V"
     CDS             complement(6486..7436)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg110_9"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.9e-58, bitscore:
                     187.5, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLTEIYDVIIIGAGPAGLSAGLYASRSRLKTLIIEKEKPGGQIV
                     TTNEVENYPGSIENSSGPSLTARMVQQADEFGAERIIDTVLEVNLDDKIKTIKGEKNEY
                     KAKAVIIATGAVPRPIGIPGEKELTGKGVSYCATCDGAFFTDLEVYVVGGGDAAVEEAI
                     FLTKFARKVTIIHRRDELRAVKSIQEKAFKNEKIDFMWDSVVKEIKGDGLVSSMVVENT
                     KTGEQTEVVADEDDGMFGIFVFIGYLPATEIFEGKVNMENGYIPTDAEMRTNVDGVFAA
                     GDCRVKTVRQVVTATGDGAIAAIQAEKYISEVFDD"
     CDS             complement(7509..7883)
                     /locus_tag="ctg110_10"
                     /transl_table=11
                     /translation="MTESIIVTNNPLVKNRLKEKVFLEYYDVDYLKLLEIVRDKVHLGY
                     KLLTHPLSGSVKPNETPYKTVIVSENSNLDTESLMIIENSIATTKKMLDINNTPPWNKE
                     ILEDFQVIDLSLIEGVLYRL"
     CDS             complement(8350..9957)
                     /locus_tag="ctg110_11"
                     /transl_table=11
                     /translation="MEIAFGVFGGLGLFLYGMNLMGMGLQKAAGERLKKLIEVLTNNRL
                     MGVLVGALVTMIIQSSSATTVMVIGFVNAGLMTLNQAVGVIMGANVGTTITAQLIAFNL
                     TDFAPIALGVGVGIWLFTSRKSAKDFAEILIGFGLLFMGMDLMGNSLAPLSENPAFKSI
                     MISLNDPFLGVLVGLGLTTILQSSSASIGLLQALAREGLISLNIAFPILFGDNIGTTTT
                     ALLSSIGTNKTAKRAAIIHFLFNLIGTIIFMTLLRTPIQKVVLALTPGNIQKQIANAHT
                     IFNILNVIIQFPFAGLLVKAANKLVPGDIEEEGVGLKFLDSRIIETPSIAVGQVSKEVS
                     RMGKVVEKNLETSAKAFFSKDSKLIQEVFQQEKVINRLETDITEYLVELSNAPLTKEQH
                     NAVNTLFNAVNDIERVGDHADNLAELAQYRIDHKLRFTDEAIDELKVMFDKVENVYILA
                     VEAFKNTDFKKAEEVLKMEEEVDFMEKQYRANHIDRLNNLACQPSAGVIFLDLISNLER
                     ISDHSSNIAQYVLDKQNS"
     CDS             complement(10066..10533)
                     /locus_tag="ctg110_12"
                     /transl_table=11
                     /translation="MSLNIVLVEPEIPQNTGNIARTCALTETKLHLVKPLGFSVEDKYL
                     KRAGLDYWNLVDIFYYDSFEELIEKHKKEKFFYATTKGKKKHTEMEYFDECFLVFGKET
                     KGLPMDLISENWDRTIRIPMKKDIPRSLNLANSVNIILFECLRQLDFPNLE"
     CDS             complement(10624..11445)
                     /locus_tag="ctg110_13"
                     /transl_table=11
                     /translation="MKYKLIAIDMDGTLLNSKNEISKKNKEAIKKVTDKGVKVVLSTGR
                     IFPSALHYAKSLEIETPIISCNGAYVAEHGKLNIIYEKPISVEASKEVINLAEKKGIYY
                     HFYDDTTFFARRFSETVNNYYKLNEKIDEKERIDIRIIDNPIEIIDSEKPLVYKFVFVE
                     DDREKLLEFRKEAIKIDGIEVASSWWNNVEIMNKGVSKGRALIELCNVLNIDRSEVVAI
                     GDNENDIPMLKIAGLSIAMGNGEEEVKKIANVVTKTNDESGVGEAIEKFVL"
     CDS             complement(11546..12802)
                     /locus_tag="ctg110_14"
                     /transl_table=11
                     /translation="MNYALEVENLNFAYRKQLVLKDISFFIEKGQFISIIGPNGSGKST
                     LLKNLSNLYNPESGFIKVYGKDIKKYRTKELAKNISLVPQDTTISYDFTVFDIVMMGRF
                     PYLDRFKKENEKDFKIVAEALKKTNTFHLRNRNINEISGGERQRVIIARALAQESEIIF
                     LDEPTSHLDINHQIDLLNLLKQLNEEKGTTIILVIHDINLACRYSDKIILMDKGEIVSK
                     GTPIEVITRKNIEKAYGLNVIVEENPYTDSLYIVPLSLNNSIDQNKKRNKKIHVIAGGG
                     TSGEILSKLEEKGYDVSVGVVNVGDSDWQLAKKLSLDVVDERPFSAISEKSFKENMEAI
                     GKSDVVILSSIPYGEGNLKNLEAAYNGLKMGKKVYLVNKYTKYDKFDYTEGEGLKILES
                     MKKDGLIIINSIDQFTKEG"
     CDS             complement(12818..13867)
                     /locus_tag="ctg110_15"
                     /transl_table=11
                     /translation="MIFKKLKNKYATIIIILSILLIFCIGLFATIGTANIKVADTFKII
                     FSRFPYIGDMIDVSGISDSYKTIILNIRLPRVLLGVLVGASLASAGTAFQGMFKNPMAD
                     PYVIGISSGAALGASIAIISGIEINFLGISSTSLFAFLGSIITVFTVYFISKVKGKVPA
                     TTLLLSGIALGQFFTAIMSFLMVLYTKDMEKIIFWTLGSFSGKGWEPLIRITIPTTISI
                     IFLNFFARDLNIILTGEESARSLGVEVEKVKIYILILSSFMTSMVVSVSGIIGFVGLII
                     PHIVRLMVGPDHRILMPASALVGGIFMIFTDTIARTIISPTEIPVGIITALFGGPFFIY
                     LLRKKKREI"
     CDS             complement(13882..14841)
                     /locus_tag="ctg110_16"
                     /transl_table=11
                     /translation="MKRFKNKKTLMLVLVLALTLVAFTGCGNSNKAEDSNEKVETEGEN
                     STYPLEVEDQFKNKVTIEKEPERIVSLAPSHTEILFSLGLEDKIVGVTSFCDYPEEAKE
                     KDKIGDYEGINIEKVIELEPDLVVQYGKGDEGINSKIKEAGIPIVSYEPESIDEVINTI
                     NEIGKVTGKEEEAKKITEDMKAKKDEIVDKVKDEERAKVFYEIWHDPLMAAGPGSFMDE
                     LINLAGGENIAKDAKEEYTEFDQEQLIERNPDIYLAAEDTEDKTVESIKSRPGYETINA
                     VKNDKVYLLEPNIVSRPGPRIVEALELVAKTLHPDLFE"
     CDS             complement(15050..15721)
                     /locus_tag="ctg110_17"
                     /transl_table=11
                     /translation="LEKVEELYDKKVQCPVCNQEFITNKVRTSKLRLIKRDSDFLTYYE
                     GENPIKYNVFVCQHCGYASMEDKFHNINSKEKKIILDKVSSKWNKRSFSGRRSIEKSIE
                     AYKLSLYCGQLLNFEKYNLANICLRTAWLYRIKKDSNEEKRFLHFTLDLYREAYYNEYL
                     TDSTMDELTLTYLIGEISRRLGKKEEALNWFNNVLRNPEIKDNRVIERMTREQWQLAKE
                     S"
ORIGIN
        1 aatagtaatg gagcgggatt taagaaaatc ccaccccaaa tattgacaaa gagccacttt
       61 ttataatatc tcacaaaaac actccaagtt taccttggag gcttggagtg ttttaacaaa
      121 tattagattc atttgaaata tagccttctt tggctaatat gcttatagca ttttcaactt
      181 taccttcatt aaccattaaa actggtcctg tacatcccat tccactttct gcatatattc
      241 catttttcca gagaaccttc actgcatctt ctaattccat aatatctatg ccagaaatag
      301 tccctgttac cgtttccttt tctggaggaa taatttcttc atcaacagtc cctttcttac
      361 tatcctttgt tatcccttca agcatttctt taaaacctgc actatttacc tttttaaatt
      421 cttctttagc cacttcattt atatttcctt tagatagact agcaccataa ctaatagcat
      481 tagctacaac tggtactcct gaagctcttg aaagaataag tattgttctt tcataacctt
      541 ctccaattcc tggaccatat ccataaccta atgattcata gtttccacct gtagtgtaag
      601 atgaaaacat ctttattaat atatttcccg ttaaagtatc tgttatcatt acatcaggta
      661 ctccactaag taaatcattt cctctcatta cacatccacc atctgctctt agtgattcag
      721 taaagttgat tttatatcca tttttatcaa gctctttcaa tgctctttcc acttgtatag
      781 caccatctac atttaatatt ccaactgtag gattatctat acccatagct ttagcagtaa
      841 tgattccata tatcccattc atgaccattg cttctactct atgtggtgaa gaagtacctg
      901 tagttgtagc tatgaacatt tccttgcctt tgcctggtgt tataactctt cccacagtag
      961 aaactccaat tggaaaacta taatgcatag ttacagcaga atctatttca ttattatcta
     1021 acaattcctc cattttctta taaccttcat cttcagtttt cgctactact tgagtcagtg
     1081 aactatctac ttttgggcct attaaaacaa cctcaatatt tgaatctctt tcttgagcta
     1141 tttccgcgcc tttaactaca ttttctacac catgttcact tccgagagta gttataccta
     1201 ctcttatttt ccttccaaac tgtcctgttt ctaaagcatc tgctatatca ttaaaaactt
     1261 tacctaccat acttttcaca ttattatctg tcattttatc acctctactc ctttagtaga
     1321 tgagaggcaa aatctctcat agcttctgct acaaggcttc ttatttcttc ttctgatact
     1381 cctttttctt catctacttt tccaggattc ttttccataa ctatggatac cccatcaaat
     1441 aaattagtca ttctacctaa aaataaacta ccttttccta taatcattgc attttttatt
     1501 ttgttattta atatatcttc tctagcaaac cctacataag gtactcctga tggaatatgt
     1561 ccttgagttg gtgcccaacc ttccatacca tgtgtttcta taaaatcatt taactgggtc
     1621 ctttccaatt cctttctcat tacacctaat gcaccaatca ttttataatt agcctttggt
     1681 acatcccctg ctcctgcagg ttttgttata tctggatttt gcatttctac tgagtattta
     1741 tctatatctg ttatttttaa gtcaccttta tcaagaggtt cagttacaag agaacttata
     1801 actgcttgag gtgaagaacc tgttcctact gtatgccttc ccactagatc ggttctaagt
     1861 attggattaa ctccatcatt ttctcctata ataattgcaa atcctccaac tacatcctct
     1921 aatactggta atcctttttt aatatgatct ttaccattca tacctagttt agctgttgaa
     1981 ccacctgcta ctactactac attcttaaat attttagcgt caactaatgc agcagcttct
     2041 atcatggcat gtgtaggagc ggcacagaat cctctagtat ctgaacctgt agcatttgta
     2101 aaacctgcca tttcaccaac tgcttttgca aaattccctc cacctctttg attcatatct
     2161 ccacaagctt cttctgaaca ttcaattata tattcaactt cctctggatt aatattattt
     2221 ttctctataa gatttaaagc tgctaaaacc cctgaagctt ttgctactaa attttcaaat
     2281 agcacatggg cgctaaggtt aacatcaatg tcatgagctc tcttaacgca acctacaagc
     2341 tctccattat tatataatcc ttcagcacct tgttcttcta cagatttttt tatgctttct
     2401 atttcttctc cttctttaag tcttaatatt aaatcttctt tcataaaatg gtgtgttccc
     2461 agtttttgtt taacatcttc tgtgaatttt ttttctaact taactaaatc aaaagtatct
     2521 acaattttca taagacctat aaattcatct tgaggcatta tttccccaaa tttgcctact
     2581 ttatctgccc cttcaacttt cttatcatgc caaggcattt tatattcttt taattcttct
     2641 ggtgttatat tcccaatata tgtttgattc ggcggataac taactacttc ttcaaaactt
     2701 ctaatatgtt cgggtaagtt ttttaaataa tctgaatttg gattgattgt tttttctgta
     2761 gtttgtgtag ttccattatg caagatcatg tctggcgtat gtatcaaaac atatcctgag
     2821 cctttaacta cagcatgagc cataaattac acctccaata atataagctt ataaataatt
     2881 cttatatctt ttagataagg gccaggccct tatctaaaag atattatgat tttgttatta
     2941 ttcttcaaat atcgtttgct cttctacttc agtggttaaa gcttttaaag ctctctctat
     3001 taattttctt ctaatacttt tttcttcttc aaaatctaaa ttagggttac ctaatgggtg
     3061 aggaattgct attgttggta ctattctatt agctcctaca gtcatagaaa taggagttac
     3121 agtacacata tgaactacag gaattcctgc cctttcaatt tctttaacca tcgttgctcc
     3181 gcaacgtgta caggtacctc aagtggaagt taagataact gcattaactc catcagataa
     3241 taactctttt gcaatttctt ccgcaaaagc ctttgcacta gcaacagccg ttccgtttcc
     3301 cactgttgta taaaaatacc tatgaaggct tcctattttg ccttctttct ccaaatccct
     3361 taaaacatct actggcaaca ctctatctgg atcttcattt gcatataccg gatcatatcc
     3421 cccatgagct gtttcatgag tttccttagt tagattatcg ataccttcaa tatcgtactt
     3481 tccatattta gaagcactag aagattctat atgatctgga tttcctttag gaacaattcc
     3541 accagatgta accaacgcaa tttttgcctt tgacaaatct ttaatagctg cttctggttc
     3601 taccctatca aagtcaggca ttggaaactc tgttacaaac tcttctcctc ttaacttttt
     3661 aaggagcata tccacagctc tttcagaacc tcttttttct gcaaaataat tctttcttac
     3721 acctcttgca atatatccct cttcttctgg agagcctata tcttctcctt tagcaagttt
     3781 taatgctaat ggcaccattt gttttactgc atttctcata cctgctgcac tattcttagt
     3841 tgaaactata taaacacttt tcttaaacat atctgcacca ggattttcta catacatacc
     3901 tgttaaaaca ggtatgccca attctttatg aactgcatct gttatagttc cacaagctac
     3961 accatatctt cctgcattaa aagctggacc tgctatgaaa atatcgggat catatttttt
     4021 taccatttca actatttcgc ttttagcttc ttcaatattt tcattaaaat aactgtcacc
     4081 gcatataatt gttgcaacta tttcagcttc tcctttaaat ccagcattta tagccattcc
     4141 cggtccaaca attccttctc gaacctctgg tttataatct gctttttctt ctccgcctat
     4201 tcctgcaaaa aactgattta tatagtgaac agctttgatt tttgccattt actccccccc
     4261 tctctcgtat ttaagtgggt attaatcatt aaatttacaa aactcgtccc ttatgccttt
     4321 aacttcttca attatttcat caacatctaa aaccatttcc atcataccaa tttgttcgtc
     4381 ataaacatct ggatctactg cttctttaaa ttctggctct acaacatgat atactctaag
     4441 tcctaactgg actcctgcta atggacctgc aaaagttggg tctcctgctg ttacagtttc
     4501 agctgctaaa cctgcagctt ccgcttcagc tccacctatt aatacgatta cattttcttc
     4561 accgtatttt tcagcagctt ctttaaccct cttttgattc tctaagtcca tagctcctgc
     4621 agcagttcag acaaaacatt cagttgatga gaaaactact tcgccaccag ttgtctttat
     4681 acactcttca atagctggtc ctggtatacc atccctgtca cctataatta ttatcttttt
     4741 accatcaaat agtgacatat tctcacatcc tttcttattt tttaatatct cttaataacc
     4801 tttagcagtt aatttgttaa aaccaagttc attagttgct ccagttatag cttgtaattc
     4861 tacaactata ctaccatctt ctttcaaact tccatcaaat cctcctgcaa ttgtatctac
     4921 ataacttgta tctccaataa ttttatccat tggaggaaga gttattactt catttgcatt
     4981 tccacctgtt actacagcat tagctagtgg atcagcgtct gcaagagatt gacttgctcc
     5041 atcccttcct gcatattcat ctgtaattat tactgttttt ataccttttt gctctatttt
     5101 cttgcagttc ataataagat ctgtatctgg attaccaaag ccttcttgag agattagcac
     5161 tccatctaat cctaagaact cagctagttt tgctgtccaa tttgatgatc tttccttgtc
     5221 tgccaaataa acattttcat tagtgattat tactccaata aaattcaatt ccttaccatg
     5281 ttttgcaaac aaatctttga ctaccggatt gtttaagtga tgataagttg tattcttatc
     5341 acatgctgaa acacagtttc cactaacaat tgcaccatcc attatttctg ttggataaat
     5401 aatagttggt aaagactctt ttgcgtctac gccataaaca taggtatcat gaagtaaacc
     5461 ttgactttga agcatttgaa cataagctac ttttggaagt tctggatact tattgatact
     5521 ttcaagcata ggctctgttt caaaaatttc tacttcatca ggagttaaat tctttgctac
     5581 ttctcctaaa taagtagcag ccttaaatcc agccattctt aatgctcttt catgttcatg
     5641 ttgcttaagt ccctctttag gttcacaaac taaaactata ttgttcaatt tagaaaatgg
     5701 agtataatca gctcctggac cagtcatatc aatgataccc tcttgaaacc ctactatctt
     5761 tcctgcagta actactgcac agccttttaa cacattggtt ttaccacttc caacagtatc
     5821 taccttggaa atcattcctg ggaatattcc tcctggcccc tctactttaa cccttggttc
     5881 aataacgtct tttacaggtg ttattctaat gctttcacct ggccttgcca attctaaatc
     5941 tactttttca aaatgttcat cttctttaat aagatttact agctcatttt tgtttacata
     6001 taatgtcttg ttttctagtt ttgtctcttc ggcaaattga acatcttcaa taaataaata
     6061 gcctaattcc agacgcatac agtcacctcc tcttgtttta aaaaatatct attttaattc
     6121 taggcatatg cctagaatta aaatctaaac atacttttta atcatttctt ctacactttt
     6181 ttctgttgct tcttctttaa ctctttcatc aattttttct ccatctttat atatagcaat
     6241 aacaggtaaa cccaatacct tttgtgaaat agcaagtctt cttgccttca ttgtatcaag
     6301 tttgcaaaat ttcattttat ctccatattg tttttctaat tcttcaatat gtggcataag
     6361 tgctttacat ggctcacaac cttgactcca aaagtctacc aatacatagc catcagcctt
     6421 taacacttcc tcttcaaaag tttttttgtc aacctctaac ataattatcc ctcctaatta
     6481 tatttttaat catcaaaaac ttcactaata tatttttctg cttgaatagc agcaatagcc
     6541 ccatcaccag tagctgtaac tacctgtctt accgttttaa ctctacaatc accagcagca
     6601 aatacaccat caacatttgt tctcatctca gcatcagttg gaatatagcc attttccata
     6661 ttaaccttac cttcaaatat ttcagttgca ggtaaatatc ctatgaacac aaatatacca
     6721 aacatgccat catcttcgtc agctactact tccgtttgtt ccccagtttt tgtgttttct
     6781 actaccatag aacttactaa gccatcacct tttatttctt taacaacaga atcccacata
     6841 aaatctattt tttcattttt gaaagctttc tcttgaatag atttaactgc tcttagttca
     6901 tctcttctat gaattatagt tactttcctt gcaaatttag ttaagaatat agcttcttct
     6961 acagctgcat ctcctccacc aactacataa acttctaaat cagtaaagaa tgccccatca
     7021 caagtagcac aataagaaac tcctttacca gttaattctt tttctcctgg aatacctatt
     7081 ggtctaggta ctgctcctgt agctattata accgcctttg ccttatattc gtttttttca
     7141 ccttttattg ttttaatctt atcgtctaaa ttaacttcaa gaacagtatc aatgattctt
     7201 tcagcgccaa attcatcagc ctgttgaacc attcttgctg ttaaagatgg tccactagag
     7261 ttctcaatag aacctggata gttttcaacc tcatttgtag ttactatttg tcctccaggt
     7321 ttttcttttt caattattag agtcttaagt cttgatcttg atgcatataa tcctgctgaa
     7381 agccctgcag gacctgctcc tattattata acgtcataaa tttctgtcaa attcatctcc
     7441 tccttaatta tagtatggat ataatttact gctcggtatt aaacttaccg aaaatatttt
     7501 tatttatact acaatctata taatacccct tcaatcaaag ataaatctat tacctgaaaa
     7561 tcctctagta tctctttatt ccaaggaggt gtattattga tatctaacat tttttttgta
     7621 gtggctatac tgttttcaat aatcataagg gattctgtat caagattact attttctgat
     7681 acaataactg ttttatatgg ggtttcgtta ggcttaacac tgcctgataa tggatgagtc
     7741 aataatttat atcctaagtg aactttatct ctcactattt ctaacaattt taaatagtca
     7801 acatcataat attctaagaa aactttttct ttcaatctat ttttaactaa aggattattt
     7861 gttactataa tagactcagt catagacttc tctccttaat ttttataaag actcatgttt
     7921 ttttaaaatt aatgtgtcta ttgacagttt taataaagat tgttaatttt ttctctatct
     7981 agtttaggta taaaaaaaga atagaaaaga cacattatgc ctatctactc tgttttataa
     8041 cctgagagtt tctcctcctc tatacgagga ggattgctcc ttcggtgtgc tttcgctttc
     8101 cagagaactg tccaaatgcg attcttttgc ctgagagttt cattatagag tggcaaaacc
     8161 tataacttac tccttcggcg ccaaattttg gtctctcccg catttttcat acagttggtg
     8221 aaaagatatt attattatgt atgtactaga ttattgaatt ttattgtttc cacttttatt
     8281 ataatatata attccataaa atacaatata attatcaatc aatacaaaaa tttaacattt
     8341 aatatattat tagctatttt gtttatctaa tacatattga gcaatatttg atgaatggtc
     8401 agaaattctc tctaaattac ttattaaatc taaaaatatt actcctgcac ttggttgaca
     8461 agctaaatta tttagtctgt caatatgatt agctctgtat tgtttttcca taaaatctac
     8521 ttcttcttcc atcttaagaa cttcttctgc ttttttaaaa tcagtatttt taaatgcttc
     8581 tactgctaat atatatacat tttctacttt atcgaacatt acttttaact catctatcgc
     8641 ttcatctgta aaccgcagtt tatgatctat tctatattga gctaattctg ctaagttatc
     8701 tgcatgatcc cctactctct caatatcatt tactgcattg aaaagagtgt tcactgcatt
     8761 atgctgttcc ttagttagag gtgcatttga aagctctact aaatattcag taatatctgt
     8821 ttcaagtcta ttaattactt tttcttgttg aaaaacctct tgaattaatt ttgaatcttt
     8881 gctaaaaaat gcttttgctg aagtttctaa gtttttttct acaacttttc ccattctgct
     8941 tacttctttt gaaacttgac ctacagcaat ggaaggtgtt tcaattattc ttgaatctaa
     9001 aaatttaagt cctacccctt cttcttctat atcaccaggc accaatttat tagctgcttt
     9061 aactaataat cctgcaaaag gaaattgaat aattacattt aaaatattaa aaatagtatg
     9121 agcatttgca atttgttttt gtatattacc tggtgttaac gctaaaacta ctttttgtat
     9181 aggtgttctt aataaggtca tgaaaataat tgttcctata agattgaata aaaagtggat
     9241 tattgcagcc ctttttgcag ttttattagt tcctatactt gataaaagtg ctgtagtagt
     9301 tgtccctata ttgtcaccaa ataatatagg aaatgcaatg ttaagactta ttaatccttc
     9361 ccttgctaaa gcttgtaaaa gtccaataga ggcactacta ctttggagaa tagttgtaag
     9421 accaaggccc accaaaactc ctaaaaacgg atcatttaag cttatcatta tgcttttaaa
     9481 agcaggattt tcacttaatg gtgccaagct attgcccatt aaatccatac ccataaaaag
     9541 aagaccaaat cctattaata tttcagcaaa atctttggca ctttttcttg aagtaaacaa
     9601 ccatatacct acacctacgc ctaatgctat tggagcaaag tccgtcaaat taaaagctat
     9661 aagctgggct gttatagttg tacctacgtt ggctcccatt attacaccaa cagcttgatt
     9721 aagagtcata agtccagcat ttacaaatcc aattaccatt acagtagttg cactactact
     9781 ttgaataatc attgtaacaa gtgcacctac taaaactccc ataagcctat tattagttaa
     9841 aacttcaata agttttttta atctttcgcc agcagctttt tgaagtccca tgcccattag
     9901 gttcatgcca tataaaaaaa ggcctaatcc accaaagaca ccaaaagcaa tttccattta
     9961 ataatccccc taactttttc atataaagta ttttaataag ccttatatat agtacattat
    10021 ttttttaaaa gatttgttaa atctatgtta attttattaa ttttcttact ctaagtttgg
    10081 aaaatcaagt tgtcttaaac attcaaataa aattatattt acagaattag caagatttaa
    10141 ggatcttgga atatcttttt tcatggggat tctaatagtt ctatcccaat tttcagaaat
    10201 taaatccatt ggtaaacctt ttgtttcttt accaaaaacc aaaaagcatt catcaaaata
    10261 ttccatttca gtatgctttt tctttccttt tgttgttgca taaaaaaatt tttctttttt
    10321 atgcttctct atcaattctt caaagctatc ataataaaat atatctacta agttccaata
    10381 atcaagtcct gctcttttta aatatttgtc ttctacagaa aaacctaaag gttttactaa
    10441 atgtaattta gtttctgtaa gggcacaagt tctagctata tttcccgtat tttgcggtat
    10501 ttctggttct actaatacga tatttaatga catttaaatc tcctcttttc ttagtttttg
    10561 cttatctaaa aaaagtatac cataattact gtagtaatgt aatattcttt attgcaatat
    10621 tctttataat acaaactttt ctattgcttc tcctactccg ctttcatcat ttgtctttgt
    10681 aactacatta gcaatttttt ttacttcttc ttctccattt cccatggcta tagaaagacc
    10741 tgctatttta agcataggta tgtcattttc attatctcca atagctacta cttcacttct
    10801 atctatattt aatacattgc ataactctat caatgctctt cctttagaca ctcccttatt
    10861 cataatttct acattattcc accaggaact tgccacttca attccatcta ttttaatagc
    10921 ttctttccta aactctaaaa gtttttctct atcgtcttct acaaatacga atttataaac
    10981 taaaggtttc tcactatcta ttatttcaat aggattgtct attattctaa tatctattct
    11041 ttccttttca tctatttttt catttaattt ataataatta ttaactgttt ctgaaaatct
    11101 ccttgcaaaa aaggtagtat catcataaaa gtgataataa atcccttttt tttcagctaa
    11161 gtttataact tctttagaag cttcaaccga aataggcttt tcatatatta tatttaattt
    11221 accatgttcc gctacatagg caccattaca gcttattata ggagtttcta tttccaaaga
    11281 tttagcataa tgtaatgcag aaggaaagat tctgccagta gaaagtacta ctttaacccc
    11341 tttatctgta acttttttta tagcttcttt gtttttttta cttatttcat ttttactatt
    11401 caatagggtt ccatccatat ctattgcaat taacttatac ttcatttaca tcctcctatc
    11461 ttttttataa accacataaa agtataccat aaatatatga aaacattaat acaaataaaa
    11521 agtaatttac aaaagaaggc tagaactagc cttcttttgt aaattgatct atagagttaa
    11581 taattataag tccatctttt ttcatcgact ccaatatctt taatccttcc ccttctgtat
    11641 aatcaaattt atcatattta gtatatttat ttactaaata cacttttttt cccattttca
    11701 atccattata agctgcttct aagtttttta aatttccttc tccataaggt atgctactta
    11761 atattactac atctgatttt cctattgcct ccatattttc tttgaaagat ttttcactta
    11821 ttgctgaaaa tggcctttca tctactacat ccaaagataa tttttttgct aattgccaat
    11881 cactgtctcc tacatttact actcctacag atacatcata gcccttttct tctaacttac
    11941 ttaatatttc tcctgatgta cccccacctg ctattacatg aattttttta ttcctttttt
    12001 tattttgatc tatactatta tttaaagata atggcactat ataaagacta tcggtataag
    12061 gattttcttc aactataaca tttagtccat aagccttctc aatatttttt cttgttataa
    12121 cttctattgg agttcctttg ctcacaattt ctcctttgtc catgagtatt attttatcac
    12181 tatatctaca agctaaatta atatcatgta ttactaatat aatggtagta cctttttctt
    12241 catttaattg ttttagtaaa tttaataaat caatttgatg gtttatatct agatggctag
    12301 taggttcatc taaaaaaatt atttcagact cttgagccaa agctctagca attataactc
    12361 tttgcctttc tcctccactt atttcattta tgtttctatt ccttaaatga aatgtatttg
    12421 tttttttaag ggcttcagct acaattttga aatctttttc attttctttt ttaaatctat
    12481 ctaaataggg aaaccttccc atcatcacta tatcaaatac agtaaaatca taagatatgg
    12541 ttgtatcctg aggaacaaga gaaatatttt ttgccaattc ctttgtcctg tactttttta
    12601 tgtccttacc atataccttt ataaaaccac tttccggatt atataaattg cttaaatttt
    12661 tcaataatgt ggatttgcct gagccgtttg gtccaataat acttataaac tgtcccttct
    12721 ctataaaaaa agatatatct tttaaaacta attgtttcct ataggcaaaa tttaaatttt
    12781 caacttctag tgcataattc ataatgttca ctcctagtta aatctctctt tttttctttc
    12841 gcaataaata tatgaagaag ggtcctccaa ataaggctgt tataattcct acaggtattt
    12901 ctgtgggaga tataatagtt cttgcaattg tatcagtaaa gatcataaat atacctccaa
    12961 ctaatgcaga agctggcata agtattctat ggtctggtcc taccataagc ctaactatat
    13021 gaggaattat taaacctaca aatccaatta ttccacttac agataccacc atagatgtca
    13081 taaatgatga taatataagt atatatattt taaccttttc tacttctact cctaaacttc
    13141 tagccgattc ttcacctgta agaattatat ttaaatccct agcaaaaaaa tttaggaata
    13201 taatagatat tgtagtaggt attgtaatac gtattaaagg ttcccatccc tttccagaaa
    13261 aactacctaa tgtccaaaaa attatttttt ccatatcttt agtatacaat accatcaaaa
    13321 aagacattat ggcagtaaaa aattggccta aagctatacc tgacaataaa agggtggtag
    13381 caggcacttt accttttact ttagatataa agtagactgt aaaaactgta ataatagaac
    13441 ctaaaaatgc aaaaagggat gtagaagaaa ttcccaggaa atttatttct attcctgata
    13501 ttatggcaat agaagcccct agggctgccc ctgatgatat acctattaca taggggtcag
    13561 ccatagggtt tttaaacatt ccttgaaagg cagttcctgc actagcaaga ctagctccaa
    13621 ccaacacacc aagcaatacc cttggcaatc taatatttaa gattatagtc ttataggaat
    13681 cagatattcc acttacatct atcatatccc caatataagg aaatcttgaa aatattatct
    13741 taaatgtatc agctacttta atattagccg ttccaatagt agcaaatagt ccaatgcaaa
    13801 atatcaataa aatagataat attataatta tagtagcata tttattcttt aactttttaa
    13861 atatcatata aatccctgct tttattcaaa taaatctgga tgcaatgttt tagctactag
    13921 ttctaaagct tctacaattc ttggtccagg tcttgaaact atattaggtt ctaatagata
    13981 taccttgtca tttttaacag catttatagt ttcatatcca ggtctagatt ttattgattc
    14041 taccgtttta tcttctgtat cttcagctgc taaatatata tcaggatttc tttcaatcaa
    14101 ttgttcctgg tcaaattctg tatattcctc ttttgcatct ttagctatat tttctccacc
    14161 agctaaattt attaattcat ccataaaaga tccaggacca gcagccataa gtgggtcatg
    14221 ccatatttca taaaacactt ttgccctctc ttcatccttt actttatcca caatttcatc
    14281 ttttttggct ttcatatcct ctgttatttt tttagcttct tcttctttac cagtaacttt
    14341 acctatttca tttatagtat ttattacttc atctatagac tctggttcat aagatactat
    14401 aggtatacct gcttctttta ttttactatt tattccttca tcaccttttc catattgaac
    14461 tactaaatct ggttctaatt caataacctt ttcaatattt attccttcat aatctcctat
    14521 tttatctttt tcttttgctt cttccggata atcacagaaa cttgttactc ctacaatctt
    14581 atcttctaat cctaaactaa aaagtatttc tgtatggctt ggtgctaatg aaactatcct
    14641 ttcaggttcc ttttctatag tgactttatt cttaaactgg tcttctacct ctagagggta
    14701 tgttgaattt tcaccttcag tttcaacctt ctcattacta tcttctgctt tattagaatt
    14761 tccacaacct gtaaaagcaa ccaatgttaa tgctagtact aatactaaca ttagtgtttt
    14821 tttgttttta aatcttttca tatgtattcc tccatccttt agttaattaa atactatatt
    14881 tcaaggaaat gatatcaaat aatcttaata gattcaagac tagaatatta gctaaatatt
    14941 tctctaaaat cttataccag cttcttcatt ctcattatgc aataataact ttagtattct
    15001 tcaccttgta aatgctatat ttattttcct attgtgcttt catttatcac taactttctt
    15061 tagctaattg ccattgctct cttgtcattc tttcaataac cctattatct tttatttcag
    15121 gatttcttaa aacattgtta aaccaattta aagcttcttc cttctttcct aatcttctcg
    15181 aaatttcccc tattaaatac gttaaggtca attcgtccat agtgctatca gttaaatatt
    15241 cattataata ggcttctctg taaagatcta aagtaaaatg taaaaatctt ttttcttcat
    15301 tgctgtcttt ttttattcta tacaaccaag ctgttcttaa acaaatatta gctaaattat
    15361 atttttcaaa gtttaatagt tgtccacaat atagtgataa tttatatgct tcgatggatt
    15421 tttcaatact tcttcggcct gaaaagcttc ttttattcca ttttgaagat actttatcta
    15481 atataatttt cttttcctta gaatttatat tatgaaactt gtcctccata gatgcgtaac
    15541 cacaatgttg gcatacaaat acattatatt ttataggatt ctccccttca taataagtta
    15601 aaaaatccga atccctttta attaatctaa gtttagaggt tctaacctta tttgttatga
    15661 attcttgatt acatacggga cattgaactt ttttatcata caattcttct actttttcca
    15721 atttaattcc tccatttttt atttattatt ctgtatttaa gctatatctt caacttcttt
    15781 gttagaggaa ataatagttt attatctttt tctgttttta tctccatata tatatatttt
    15841 tacatt
//
