LOCUS       c00021_NZ_CALE..       14930 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CALERU010000021.1 MAG: Desulfovibrio piger isolate
            ERR318677_bin.72_CONCOCT_v1.1_MAG ERZ1764591.8, whole genome shotgun
            sequence.
ACCESSION   c00021_NZ_CALE..
VERSION     c00021_NZ_CALE..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:46:20
            Original ID  :: NZ_CALERU010000021.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 332088
            Orig. end    :: 347018
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14930
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[342088:346172]"
                     /cutoff="10000"
                     /detection_rule="(DAO and Fer2_BFD and FAD_binding_2 and
                     Fer4_8)"
                     /neighbourhood="10000"
                     /product="Respiratory_glycerol"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14084
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(DAO and Fer2_BFD and FAD_binding_2 and
                     Fer4_8)"
                     /neighbourhood="10000"
                     /product="Respiratory_glycerol"
                     /protocluster_number="1"
     cand_cluster    1..14930
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(DAO and Fer2_BFD and FAD_binding_2 and
                     Fer4_8)"
                     /kind="single"
                     /product="Respiratory_glycerol"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14930
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Respiratory_glycerol"
                     /region_number="3"
                     /rules="(DAO and Fer2_BFD and FAD_binding_2 and Fer4_8)"
                     /tool="gutsmash"
     CDS             1956..2543
                     /locus_tag="ctg21_289"
                     /transl_table=11
                     /translation="MTMTAKNKKEALLQAAKELFGECGYVETTFKKISDRAGVALGLLT
                     HHYGNKEKLFLASGLDVLEHFLVKLRQATADAACGYDAVMHFCKAYLDFSVDKDSNWLV
                     LVRCSPYSDMKTKTDREQMDSMFAQVHRELEEQIQRGIRDGSIVNVDSKATAQVIISLM
                     VGANRTRVLTPYALPELYDETLDFVSRSIRKN"
     CDS             complement(2852..4186)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) UDPG_MGDP_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) UDPG_MGDP_dh"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_290"
                     /sec_met_domain="UDPG_MGDP_dh_N (E-value: 6.4e-66,
                     bitscore: 215.7, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="UDPG_MGDP_dh (E-value: 6.6e-42, bitscore:
                     135.9, seeds: 679, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLCIVGTGYVGLVSAACFAEMGNSVTCIDVNKDVVARLNAGSVH
                     IFEPGLEPMVRRSHADGRLKFTTSLAEGLVGADCAFICVGTPPGEDGSCDLHYVEQVAR
                     EIGRTMENDLIVVDKSTVPVGTADRVRAIITEELAARGKNFDFEVVSNPEFLKEGDAIS
                     DFMKPDRVVIGTSSDKAAAVMRELYAPFARTRDKLIVMGIRSAEMTKYAANCMLATKIS
                     FINEIATICERVGADVRDVRNGIGSDSRIGYQFIYPGVGYGGSCFPKDVKALIHTAEAA
                     GMEPKLLNAVEAVNARQKLHMAERIKEYFAPQGGVKGKTLALWGLAFKANTDDMREAAS
                     INIINALTEAGMKVRAFDPVAADNARRIFQDNPLVEIVDDQYGVCDGAQALLVVTEWNQ
                     FRNPDFDRIKSLLTAPLLFDGRNLYSPAAMGSRGFAYFCIGRRAD"
     CDS             4299..4670
                     /locus_tag="ctg21_291"
                     /transl_table=11
                     /translation="MLVGLGMDLTDIGRMERALQRHGTRFAARILAPAEQEACPELRPA
                     FVAGRWAAKEAAVKALGCGFSLGIGPRHIEILPTPTGKPELRFTGPALERARQLGVRHI
                     HVSITHERTTAAAVVVLEA"
     CDS             4673..6247
                     /locus_tag="ctg21_292"
                     /transl_table=11
                     /translation="MNREWWSALPPLPLPHEMQQWDRQAVELGILPEILMENAAAAAFR
                     QLGTLCPRLAGKQIWLFMGSGNNGGDAACLARYLLDAGACPHVFHTRPLDHYRNETAYH
                     LQAARSCGVPFLPVAALTEPSRALPHPDIVVDGLLGTGFSGQLRDDVLRLVSFVNDLSP
                     RPLILSLDVPSGLDATSGLPCPDAVRADMTVSFAAAKPGLMLPWARPYTGECHVGPIAM
                     PAKVREEGPCSFRLLDSRALALLPAMTAASYKNTYGHILVMGGRPGMCGAGHLAARGAL
                     RTGAGLVTAAMPAAGEDQVRMGWPEIMTLPLGDPGNRDWPAQLPDALRQRLHQCRAVVI
                     GPGMGRGEDSHAFLAALLKEPGRPACVFDADALMLLAEDPALLASLGPGDILTPHPGEA
                     AALLHCPGGTVQQDRMAALNALCAIVPSAVVLKGAGTLVGQRDCPTGLSPLDIPQLAMG
                     GSGDVLAGCAAALLARLQESPRSAHQAACLAVALHAAAGGILARTHPRRGNVAGELADA
                     LPQAMTL"
     CDS             6263..6787
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TsaE"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_293"
                     /sec_met_domain="TsaE (E-value: 9.1e-27, bitscore: 87.8,
                     seeds: 801, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDAFTFLLESLDDTACLGTLLAGMMQNAPQVRALLLQGDLGSGKT
                     TLTRSFVAALPGGDQAEISSPSFTICNNYPTCPPVLHCDLYRCPASLPDEVWDALDADA
                     GICIVEWAQYIPEAALPKEFLDIRLESCEKGRFLTVMAHGQASQALAQELHTAWTTSGR
                     HGSRTDLPLFS"
     CDS             6813..8036
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_294"
                     /sec_met_domain="AA_kinase (E-value: 3.4e-54, bitscore:
                     178.2, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKILVQKFGGTSVANLECMKKVREKVQAGLNKGYKMVVVLSARSG
                     ETNRLLALASEWSSTPDPAECDSLVSTGEQVSIALFTMLLKDAGIRARSLLAWQIPIIT
                     DDDHGNARIESIDSQRLRSYLDEYDVLVVAGFQGCTESQRITTLGRGGSDTSAVALAAA
                     LGSVECEIYTDVDGVYTTDPNICSSARKMDRVAYEEMLEMASMGAKVLHIRSVEFAKKY
                     KVPVRVRSTFSDDPGTLVTQEDSSMEAVLVSGIAYDKDQARVTLHDLPDVPGVAAAIFG
                     PLSEKGVLVDMIVQNTSLDGHTDMTFTISRKDLKQTLAIMEEVKERTGATDVVSDVNVA
                     KVSAIGVGMRNHSGVAARAFSALTQEGINILMISTSEIKITILIQEKYVELAVRILHDT
                     FGLDWDIN"
     CDS             complement(8248..8913)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_295"
                     /sec_met_domain="HAD_2 (E-value: 1.4e-31, bitscore: 104.1,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAHTSFFFDLDGTITDSKQGIINSVLYSLNHFGIRASADSLLFFI
                     GPPLKQSFARYFPGDSARVTLAVEKYREYFRRQGMFENQVYPGVPQMLERLIEQGHRIH
                     LATSKPEVFARQILDHFKLSRYFSFVAGAELNGARNDKVDVLRYALQETGADVSHSLMV
                     GDRFHDVVGGHAVGMKTVGVLYGYGSRQELESVHADYICQSMTDLQTTLLALGAEMRH"
     CDS             complement(8982..9752)
                     /locus_tag="ctg21_296"
                     /transl_table=11
                     /translation="MRLPDKRCIVLDMDGTIYMGDNPIEGAVAFVQRHWEDVDFFFLSN
                     NTSKAPETYIKKLNGMGIPARREQLLSPVTPLVAFLKAEGIHTAYVVGNRDFVSDLRQR
                     MPELKQQEEGAQAVILAYDTELTYEKLSRSALLLQKDDVRFLATHPDLVCPSPEGPLPD
                     VGSFLALYATATGRRPERIFGKPDATLLSGLLQRYAPENMLMVGDRLSTDKLLAENAGI
                     DFLLVLSGEARRSDLPGLERQPTLVLDHLGLLDQ"
     CDS             10001..11608
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Respiratory_glycerol: Fer2_BFD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Respiratory_glycerol: DAO"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_297"
                     /sec_met_domain="DAO (E-value: 2.6e-47, bitscore: 156.3,
                     seeds: 522, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 4.2e-08, bitscore:
                     27.8, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKETTVIIIGGGATGIGILRDLSMRGVPALLLEQGGLAHGTSSRF
                     HGLLHSGARYAVSDSESARECIEENMILRRIGKQCVEETEGFFVRTKLDDPAFEPGWVE
                     ACARAGITAERIDVAEARRLEPNLAPNICSVYRVPDSCVDGFRLVWHNALCARRYGGDI
                     LTYHEVIAIKQSNGKVTGVTARNRITGEELDIACEYVVNAAGSWSGQIAHLAGLDVSVS
                     PDRGTLIVFNHRFTSRVVNRLHKSSDGDIFVPHGSITILGTTSTPTDRPDNNTPTTEDV
                     LRLLDIGEPLFPDLRSYRILRAFAGTRPLYTPNNAVGRAASRNFHIVDHKQDGLEGMAS
                     IFGGKLTTYRLMAERMSDLVCRYLGNNEPCRTAEEPIMEDPSPELMQKAAKVFPLNGAV
                     LAADRLGSTFADVVEKAASETDNELLCECEMVSMAEVEYVARDPATHSLHDVRLRTRLG
                     MGTCQGTFCSLRAIGALTERNVPLAFSPTEDVSQFLQERWRGLRPALWGKQLKEIELGR
                     AIYVATLNLDGAGNEQKK"
     CDS             11592..12854
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Respiratory_glycerol: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 59.1; E-value:
                     1.4e-18)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_298"
                     /sec_met_domain="FAD_binding_2 (E-value: 6.7e-18, bitscore:
                     59.1, seeds: 62, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKRNSDVLVIGAGMSGLVAALAAARRGRKVTVLSRGVGALAIGS
                     GCVDILGYVNGQAVSGHPLDAIESLPETHPYRLLGRDRVAEACSFLEEVCAAQGLSLLP
                     MKENNRLVPSIMGTLKPSGLCPASADGDLLLKAKRVAVVTIGGLRDCQPNLIIKQFRRY
                     PALRSIEFTEVVLPSPLGKTHRNITALDLARYVDRPEGVFWLADALKKACGRQDLILLP
                     PVCGVRNFLWKKLVELLDCPVVEMLSIPPGVSGLRLRTCLLNALRELDVTLLENTTVIR
                     ADVADGHCRGVVTSGLDHEHVYTADQIIVATGGFMGDGFEAEPGKMQESIFQLPLCLEN
                     GEMPSADPSDWSEENVFARHAFATLRVRVDAQLRPCSEEGSVLLDNVRFVGRSLGGYDF
                     ATEKSGNGVALATAWYAAQCV"
     CDS             12864..14084
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Respiratory_glycerol: Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_299"
                     /sec_met_domain="Fer4_8 (E-value: 4.8e-11, bitscore: 37.2,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.009, bitscore: 10.9,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMALKHPNPDACIACTTCVVQCPVAQATTNFLGPRMIGPAYERFR
                     LLGLAEEESLHYCANCKNCDIACPQGVPVSSLNMMARAEQCRKKRPPLRDWILGHGELM
                     AKLLRYVPAKLKNFGMLNPVTRFALDKLGISAKAPMPAFAEKSFRQQLKKIWQPHTNKY
                     VVLFPGCYLDVYDPQTGLDLVWVLNQAGYHVIVPKEFVCCGLPMVANGFWDDARANAKK
                     NIAELQRWRKEGIPVITGCPSCALMFSSDLPEYYPDLMIDGVSTTLLDAQAFLLDCVEK
                     GELRLPEKTVDSSVVPSELIYHAPCHLRAQGNGLPGLDLLRALPGMHVSNADAGCCGIS
                     GSYGFKKEKYPIGMQVGSALFDAVRKSPAPVAASECGTCRVQIKHGSGKDCMHPVSVLR
                     RWLEAAR"
ORIGIN
        1 ctggtcaagg gcaagcgcct gagcgaggaa gaattcgaac atctggacga cagcctgcgc
       61 atgaccctca agcggcgtgg cgagaccctt gtccagagca tggctagctt catgcgccag
      121 ttgagcaagg ccgaagagag cttccacgac gacgaacgca atctggaaca gaccgtcatg
      181 gcccaggtgc tggacgccct gctgctcccg gctcaaaaga agctgctcaa ggcctgccag
      241 agcgaagctc tggaacagta ctttgccagc ctgcgcgcgg acatcctgaa gaacaccgag
      301 gccttcctgc cccgggaggc cggccagtcc ggcccggatg tcccccatgc gcccctgccc
      361 ccgcagggcg atccgctgta ccgctatgac gtcaacgtct tcgtggacaa cagcgaactc
      421 agcggtgccc ccatcgtggt ggaagaccat ccgacgtcat ccaacctgct gggctgtatc
      481 gaacgggaat cggaactggg cgccctggtg acggacttca ccctcgtacg ggccgggagc
      541 ctgcacaagg ccaacggcgg cttcctcgtc ctgcgggcgg aagacctgct gcagcatccc
      601 aacgcctggg aaggcctgct gcgggccctg cgagccaatt ccctgcgcat cgaggatggc
      661 gcggagaccc cggatgccgc catccgtacc aagggcatca atcccgagcc cctgaagctg
      721 gatctcaagg tcgtgctcat cggcacggaa gatctgtacg aagctctggt cctcaatgaa
      781 gaccgtttcg ccaagctgtt ccgtatcaag gcacagatgg ccgaacgcat ggaccgcaat
      841 gccgccggtg tccgtttcta tctgtcggtc atcgcccgca tcgcagaaga gtccggtctg
      901 cggccttttg accgcacggc cctagcctgg ctggtggacc tgggctcgca cctttgcgag
      961 gaccagcgtc gtctgtcgct caagttcccg ctgttgcgcg aacagatgat cgaaggggat
     1021 gccctggcgg gcatggaagg cgccgaggtc gtcaccggcg acatcatgga gcgctcctat
     1081 gccgcgcgta cctaccgggc caacctagtg gaagaaatct tcatggaaga gtacgaccgc
     1141 gagatgatca aggtctgtac gtcgggcagc gccatcggcc aggtcaacgg cctgtccgtc
     1201 accggctacg gtgatttcga attcggcctg ccccaccgca tttcctgtac cgtgggcgtg
     1261 ggccatgaag gcatcatcga tctggaaagg gaagccgaac tgggcggccc catccacacc
     1321 aaggccatga tgatcctcaa aagttacctg accaacctct tcgcccgcaa aaagccgctg
     1381 gtcctggccg gatcgcttta ctttgagcaa agctacgcgg gcatcgaagg cgactccgcc
     1441 tccggtgcgg agctggtggc cctgctctct gccctggccg atgtccccgt acggctcgac
     1501 ctggccttca cgggcgcggt cagccattcc gggcagatca tggccgtggg cggcgtgacg
     1561 cggaagatcg aaggtttctt caaggtctgt gcacggcatg gcctcaccgg cagccagggg
     1621 gtcatcatcc cccacgacaa cgtggatcat ctgatgctct ccccggacgt gctccaggcc
     1681 gtggaaaagg ggcagttcgc catctatcct gtccgcagca tcgaagaagc cctgaccctg
     1741 ctcacgggcc tgcccgtggg acgccgccgc aaggacgata cgttcacgcc cggcagcctt
     1801 tacgatatgg tggaccgccg tctggaacgg ctgggcgact atgcccagaa ctccttccgc
     1861 cggacgcgta aaggataggc gtcatgcatt gacttgcctt cattgagcga gtaaacagtt
     1921 ctggccgatt gtgaaaaaga cgcttaaccc ccgcaatgac catgactgca aaaaataaaa
     1981 aagaagccct gctccaggcc gccaaggaac tttttggtga atgtggctat gtggagacca
     2041 ctttcaagaa gatttccgac cgggctggtg tggcccttgg actgctgacg caccactatg
     2101 gcaacaagga aaaactgttc ctggcctcgg gactcgatgt gctggaacat tttctggtca
     2161 agctgcgtca ggccacggcc gatgcggcct gcggctatga cgccgtcatg cacttctgca
     2221 aggcctacct ggacttctct gtggataagg actccaactg gctggtgctg gtgcgctgct
     2281 ctccgtacag cgatatgaag accaagacgg acagggaaca gatggattcc atgttcgccc
     2341 aggtgcatcg tgaactggaa gaacagatcc agcgcggcat ccgggacggc agcatcgtca
     2401 atgtggacag caaggccacg gcgcaggtca tcatctccct gatggtgggt gccaaccgta
     2461 cccgtgtgct gaccccctat gccctgccgg agctctatga cgagaccctg gacttcgtct
     2521 cccgctccat ccgcaagaac tagtccttct tcctcctccg cttcaagcaa gatccccggc
     2581 agcctgctgc cggggatctt tttattttct acttcagaag cgctcgctta tgcaggggaa
     2641 aaacgcccct ccgtgtcggg gactgctccc ctgcggcctg cctgatggcc tatgctgttg
     2701 cggatgctcg caagatcgtt gccaaatctt cgcacggcag cccttgtccg caaggccgtt
     2761 ccctcatgct gcactcatcc tgcagtacat cctgacaaaa aagggcctgc cctttacagg
     2821 acaggccctc ggctgatctt gggtcggttt gctagtcggc gcgacggccg atgcagaagt
     2881 aggcgaaacc acggctcccc atggcggcgg gagagtagag gttgcggccg tcaaagagca
     2941 gcggcgcggt cagcagggac ttgatacggt cgaagtcggg attgcggaac tggttccatt
     3001 ccgtcaccac cagcagcgcc tgggcgccat cgcacacgcc gtactgatca tccacgatct
     3061 ccaccagggg gttgtcctgg aagatacggc gggcgttgtc ggccgccacg gggtcgaaag
     3121 cccgcacctt catgccggct tcggtcaggg cgttgatgat gttgatggaa gcggcttcac
     3181 gcatatcgtc ggtgttggcc ttgaaggcca ggccccacag ggccagggtc ttgcccttca
     3241 caccgccctg cggcgcaaag tattccttga tgcgctcggc catgtgcagc ttctggcggg
     3301 cgttcacggc ttccacggca ttgagcagct tgggttccat accggcggct tcggccgtgt
     3361 ggatcagggc cttcacgtcc ttggggaagc aggaaccgcc gtaccccaca ccgggataga
     3421 tgaactggta accgatacgg ctgtcagaac cgatgccgtt gcgcacgtcg cgcacgtcag
     3481 cgcccacgcg ttcgcaaatg gtggcgatct cgttgatgaa ggagatcttg gtggccagca
     3541 tgcagttggc ggcatatttg gtcatctcgg cgctgcggat gcccatgacg atcagtttgt
     3601 cacgggtgcg ggcaaagggc gcgtacagtt cgcgcatgac ggcagcagcc ttgtccgacg
     3661 acgtaccgat gaccacgcgg tcaggcttca tgaagtcgga aatggcgtcg ccttctttca
     3721 ggaattcggg gttggagacc acctcgaaat caaaattctt gccgcgggca gccagttctt
     3781 cggtaatgat ggcacgcaca cggtcggcag tacccaccgg caccgtggac ttgtccacca
     3841 cgatgagatc gttttccatg gtacggccga tctcacgggc cacctgctcc acatagtgca
     3901 ggtcgcagga accgtcttct ccgggagggg tacccacgca gatgaaggcg caatcagcgc
     3961 ccaccaggcc ttccgccagg ctggtggtga acttcaggcg gccatcggca tggctgcggc
     4021 gcaccatggg ttccagtccg ggctcgaaaa tatgcacgga gccggcattc aggcgggcca
     4081 caacatcctt gttgacatcg atgcaggtca cggagttgcc catttcagcg aagcaggcgg
     4141 cgctcaccag acccacatag ccggtgccga cgatacacaa tttcatatgt tttctccctt
     4201 ggggcgctct tgacgcccga cagtgataac gtcaaaacaa attgattgag tgcgtagtat
     4261 agcctttttt ttcttgagct tcaactccgg gggcggatat gctggttgga ctggggatgg
     4321 acctgaccga tatagggcgc atggaacgtg ccctgcaacg ccacggcacc cgttttgccg
     4381 ccaggatcct cgcacctgcc gagcaggagg cctgcccgga gttgcggcca gccttcgtgg
     4441 cagggcgctg ggctgccaaa gaggccgccg tcaaggcgct gggctgcggt ttcagcctgg
     4501 ggatcggccc ccgccatatc gagatcctgc ccacgccgac gggcaagccg gagctgcgct
     4561 tcaccggccc ggccctggag cgtgcccggc aactgggcgt gcgccatatc catgtatcca
     4621 tcacccatga acgaaccacg gcagccgcgg ttgtcgtact ggaggcctga cgatgaacag
     4681 ggaatggtgg tccgcactgc cgccgctgcc cctgccgcac gagatgcagc aatgggacag
     4741 acaggccgtg gaactgggca tcctgccgga aatcctgatg gaaaatgccg cggccgcggc
     4801 attccgccag ctgggcaccc tgtgcccccg gcttgcggga aagcaaatct ggctgttcat
     4861 gggcagtggc aacaatggcg gcgatgccgc ctgccttgcc cgctatctgc ttgacgccgg
     4921 cgcctgcccg catgttttcc acacccggcc tctcgaccat taccggaacg agacggccta
     4981 tcatctccag gcggcccggt cctgtggtgt ccccttcctg cctgtggccg cgctgacgga
     5041 gccttcccgg gccctgcccc accccgatat cgttgtggac ggtctgctgg ggacgggctt
     5101 ttccggccag ctgcgtgacg atgtccttcg cctggtctcc ttcgtgaacg acctttctcc
     5161 ccggccgctg atcctgtccc tggacgtgcc gtcaggactg gatgccacca gcggcctgcc
     5221 ctgccccgat gccgtcaggg cggatatgac ggtcagcttc gccgccgcca agcccggcct
     5281 gatgctgccg tgggcccgtc cgtacaccgg ggaatgccat gtgggcccca tcgccatgcc
     5341 cgccaaagtc cgggaagaag ggccctgttc cttccgcctt ctggacagcc gggccctggc
     5401 cctgctgcct gccatgacgg ccgcgagcta caagaacact tacgggcata tcctcgtcat
     5461 gggaggacgc cccggcatgt gcggtgcggg gcatctggcg gcccgggggg ccctgcgcac
     5521 cggtgccggc ctggtcacgg cagccatgcc cgccgccgga gaggatcagg tacgcatggg
     5581 ctggcccgag atcatgaccc tgcccctggg cgatcccggg aacagggact ggcctgcgca
     5641 gctcccagac gccctgcggc aacgcctgca ccagtgccga gccgtggtca tcggccccgg
     5701 catggggcgt ggggaagaca gccatgcgtt cctggcggct ctcctgaaag agccgggacg
     5761 tccggcctgc gtgttcgatg ccgacgccct gatgctgctg gcagaggatc ccgccctgct
     5821 ggcgtccctt ggccccgggg acatcctgac gccgcatccc ggcgaggccg cggccctgct
     5881 ccactgcccg ggcggtaccg tccagcagga caggatggca gccctgaacg ctctgtgtgc
     5941 gatcgtcccg tccgccgtcg tcctcaaggg tgcggggacg ctggtcggcc agcgggactg
     6001 ccccacgggt ctcagtcctc tggatattcc ccagctggcc atgggcggtt ccggcgacgt
     6061 actggccggt tgtgccgcgg ccctgctggc ccggctgcag gaaagtcccc gatcggccca
     6121 tcaggcagcc tgcctggcag tggcgctgca tgccgccgcc ggcgggatac tggcccgcac
     6181 ccatccccgc cggggcaatg tggccggcga actggccgat gccctgcccc aggccatgac
     6241 cctctaaccg gatagccccg ctatggatgc ctttaccttt ctgctcgaat ccctggacga
     6301 taccgcctgc ctcggcacct tgctggccgg catgatgcaa aatgcccccc aggtacgcgc
     6361 cctgctcctg caaggggatc tgggcagcgg caaaacgacc ctgacccgct cctttgtcgc
     6421 ggccctgccg ggtggcgacc aggctgagat ctccagcccg tccttcacca tctgcaacaa
     6481 ttatcccacc tgcccgccgg tcctgcactg cgacctttac cgttgcccgg cctcccttcc
     6541 cgacgaggtc tgggacgcgc tggacgccga tgcaggcatc tgcatcgtgg aatgggccca
     6601 gtacatcccc gaagcggccc tgcccaagga atttctggac atccggctgg agtcatgcga
     6661 aaaaggacga ttcctgacgg taatggcgca tgggcaggcg tctcaggctc tggcgcagga
     6721 gctgcataca gcctggacca catccggacg gcacggctcc cggacggatc tgcccctttt
     6781 ttcgtgagac aggtgcatca atggaatctg gcatgaaaat cttagttcaa aaattcggtg
     6841 gcacttcagt ggcaaacctg gagtgcatga agaaagtgcg cgaaaaagtg caggccgggt
     6901 tgaacaaggg ctacaagatg gtggtcgtgc tttccgcccg ttcgggcgag accaaccgtc
     6961 tgctggccct ggcctccgag tggtcctcca ccccggatcc ggcggaatgt gattctctgg
     7021 tctccaccgg ggaacaggtc tccatcgcgc tcttcaccat gctgctcaaa gacgcgggca
     7081 tccgtgcccg ctccctgctg gcatggcaga tccccatcat taccgatgac gatcacggca
     7141 atgcgcgtat cgaatccatc gacagccagc gcctgcgcag ctatctggat gagtacgacg
     7201 tactggtggt cgccggtttc caggggtgca cggagtccca gcgcatcacc actctgggcc
     7261 gcggcggctc cgatacttcg gccgttgccc tggctgccgc cctgggttcg gtggaatgcg
     7321 agatctacac ggatgtggac ggcgtctata ccaccgaccc caacatctgc tccagcgccc
     7381 gcaagatgga tcgtgtcgcc tatgaagaaa tgctggaaat ggccagcatg ggcgccaagg
     7441 tgctgcacat ccgttccgtg gaatttgcca agaagtacaa agtgcctgtg cgcgtccgct
     7501 ccactttttc cgacgacccc ggcacgctcg ttacccagga ggactccagc atggaagctg
     7561 ttcttgtttc cggcattgcc tatgataagg accaggctcg tgtgaccctg cacgaccttc
     7621 ccgacgtgcc cggcgtggcc gccgccatct tcggccccct ttccgaaaag ggcgtgctgg
     7681 tggacatgat cgtccagaac accagccttg acggccatac cgacatgacc ttcaccatct
     7741 cccgcaagga tctcaagcag accctggcca tcatggaaga agtgaaggaa cgcaccggcg
     7801 ccaccgacgt ggtctccgac gtcaacgtgg ccaaggtctc cgccatcggt gtcggtatgc
     7861 gcaaccattc cggcgtggcc gcccgtgctt tctccgccct gacccaggaa ggcatcaaca
     7921 tcctgatgat cagcacctcc gagatcaaga tcaccatcct gatccaggaa aagtacgtgg
     7981 aactggccgt gcgcatcctg cacgatacct tcggcctgga ttgggacatc aactagtccc
     8041 gctcctgcct gccggctgac cggccccggc catccgccgg caatacgctc catacgataa
     8101 gaaagcccgg tatcctgtga taccgggctt tttctttact catgcgcatg ctctgcacaa
     8161 agcgctaccg aggaaagctc ctttccgcga gggcctgccg caacggcacc gaccattctt
     8221 tttcgaccat tgagggatgg ggtcattcta gtggcgcatc tcggccccaa gggccagcag
     8281 agtcgtctgc agatccgtca tgctctggca gatatagtca gcatggacgg actccagctc
     8341 ctgacggctc ccgtacccgt acagcacgcc cacggtcttc atacccacgg cgtgaccgcc
     8401 gactacgtca tggaacctgt cccccaccat caaggaatgg gatacatcgg cgcccgtttc
     8461 ctgaagggcg taacgcagta catcgacctt gtcgttgcgg gccccgttca gctcggcacc
     8521 ggccacaaag gagaagtaac ggctcaactt gaaatgatcc aggatctgcc gggcgaacac
     8581 ttccggcttc gatgtggcca gatggatgcg gtgtccctgc tcgatcagac gctccagcat
     8641 ctgaggcacc ccgggataga cctgattttc aaacatcccc tgccgccgga agtattcgcg
     8701 gtatttttcc actgccagcg tgacacgggc gctgtctccc gggaaataac gggcaaagga
     8761 ttgcttgagc ggcgggccga taaagaacag cagactgtcc gcactggccc tgatcccgaa
     8821 atggttcaga gagtacagga cggaattgat gatgccctgc ttggaatcgg tgatggtgcc
     8881 gtcaagatcg aaaaagaagg aagtatgggc cataggcata ccggggtttg cgactacgaa
     8941 aaatgctgtc ggacgttttt attactatcg cctcttgcgg cctactggtc aagcagtccc
     9001 aggtgatcca gcaccagggt cggctggcgc tccagtccgg gcagatcgga acgccgggct
     9061 tccccgctca aaaccagcag gaaatcgatg ccggcattct cggccagcag tttgtcggtg
     9121 gaaagcctgt ctcccaccat cagcatgttt tccggcgcat agcgctgcaa caggccggaa
     9181 agcagggtcg catccggctt gccgaagatg cgttccggtc tcctgcctgt ggcggtggca
     9241 tacagggcca ggaagctgcc cacgtccggc agggggcctt ccggggacgg acagaccaga
     9301 tcaggatgcg tggccaggaa acggacatcg tctttttgca gcaacagcgc ggagcgtgac
     9361 agtttttcgt aggtcagttc cgtgtcatag gccaggatga cggcctgcgc gccttcttcc
     9421 tgctgtttca gctcgggcat gcgctggcgc aggtcggaga cgaaatcccg gttgccgacc
     9481 acatacgccg tgtggatgcc ttccgccttc aaaaaagcca ccagcggcgt caccggcgag
     9541 agcagctgct ccctgcgggc ggggatgccc atgccgttca gctttttgat gtaggtctcc
     9601 ggcgccttgg aggtattgtt gctcaggaag aagaaatcca catcttccca gtgccgctgc
     9661 acaaaggcca cggccccctc gatgggattg tcccccatat agatggtacc atccatgtcc
     9721 agaacgatgc aacgtttgtc aggaagccgc atgccgtgtc ccccaagttt caaaaatgaa
     9781 aaaaatgacg gcaaaaccgt ggcgcccccg tccggcaccc gccgccgtgc cgggattcta
     9841 cacaggccga tggcctgctg caagcggcgt ttttcccgcc tcttgcccat cttgacacaa
     9901 caatgtcctg taagtagagg aaagggacga cttccccgta taactttcgc aaacgaagat
     9961 tccaaagcta taattgtcgc tcctgtgagc ggaggacagc gtgaaagaaa ccacagtgat
    10021 catcattggc ggtggtgcga caggtatcgg cattctgcgc gacctgagca tgcgcggcgt
    10081 gcccgccctg ctgctggaac agggggggct ggcccacggc acgagctccc gcttccacgg
    10141 cctgctgcac agcggcgccc ggtacgctgt cagtgacagc gaatccgccc gggaatgcat
    10201 cgaagaaaac atgatcctgc gccgtatcgg caagcagtgt gtggaagaga ccgaaggctt
    10261 tttcgtccgt actaaactgg acgacccggc cttcgaaccc ggctgggtcg aagcctgtgc
    10321 ccgtgcgggc atcaccgccg agcgcatcga tgtggccgaa gcccggcggc tggagcccaa
    10381 cctggccccc aatatctgct ctgtttaccg cgtgccggat tcctgcgtcg acggtttccg
    10441 cctggtctgg cacaatgccc tgtgtgcccg gcgctacggc ggtgacatcc tcacctacca
    10501 cgaagtcatc gccatcaagc agagcaacgg caaggtcacg ggcgtcacgg cccgcaaccg
    10561 catcaccggc gaagaactgg acatcgcctg tgaatatgtg gtcaatgccg ccggctcctg
    10621 gtccgggcag atcgcccatc tggccggtct ggatgtcagc gtttcgcccg accgcgggac
    10681 gctgatcgtt ttcaaccacc gctttacgtc gcgcgtggtc aaccgcctgc acaaaagctc
    10741 cgacggcgac atcttcgtcc cgcacggttc catcaccatc ctggggacaa cgtcgacgcc
    10801 tactgaccgc ccggacaaca atactcccac gaccgaagat gtcctgcgct tgctggacat
    10861 cggcgagccc ctgttccccg acctgcgctc gtaccgcatc ctgcgtgcct ttgccggtac
    10921 gcgcccgctc tacacgccca acaatgccgt ggggcgtgcc gccagccgca atttccacat
    10981 cgtggaccac aagcaggacg gtctggaagg catggccagc atctttggcg gcaaactgac
    11041 cacctaccgt ctgatggcgg agcgcatgag cgatctggtc tgccgctacc tcggcaacaa
    11101 cgagccttgc cgtacggcgg aagagcccat catggaggat ccttcccccg agctgatgca
    11161 aaaagccgcc aaggtcttcc cgctcaatgg tgccgtcctt gccgccgacc gtctgggcag
    11221 cacgtttgcc gacgtggtgg aaaaggctgc ctccgaaacg gacaacgagc tgctgtgcga
    11281 atgcgagatg gtcagcatgg ctgaagtgga atatgtggcc cgcgatcctg ccacccactc
    11341 cctgcacgac gtccgcctgc gtacccgcct gggcatgggc acctgccagg gaactttctg
    11401 ctccctgcgc gccatcggcg ccctgaccga acgcaatgtg ccgctggcct tctcgcccac
    11461 ggaagacgtc tcccaattcc tgcaggaacg ctggcgtggt ctgcgcccgg ccctgtgggg
    11521 caagcagctg aaagaaatcg aactggggcg tgccatctac gtggccaccc tcaatctgga
    11581 tggagccggc aatgaacaaa agaaatagcg acgtcctggt tatcggcgcc ggcatgtccg
    11641 gccttgtagc ggcccttgcc gctgcccggc gcggccgcaa ggtcactgtc ctttcccggg
    11701 gcgtgggagc gctggccatc ggcagcggtt gcgtggacat cctgggctat gtcaacggcc
    11761 aggctgtttc cggccatccg ctggatgcca tcgaatcctt gcctgagacc catccctatc
    11821 gtctgctggg acgcgatcgc gtggctgaag cctgctcttt cctggaagaa gtctgtgccg
    11881 ctcagggcct gtccctgctg cccatgaaag agaacaatcg cctggtcccc agcatcatgg
    11941 gtaccctcaa gccgagcggc ctgtgcccgg ccagcgccga cggcgatctg ctgctgaagg
    12001 ccaaaagggt cgccgtggtc accatcgggg gcctgcgcga ctgccagccc aatctgatca
    12061 tcaagcagtt ccgccgttat cctgctctca ggagcatcga gttcaccgaa gtcgtcctgc
    12121 cctcgccgct gggcaagacg catcgcaata tcacggctct ggatctggcc cgctatgtgg
    12181 atcgtcccga gggtgttttc tggctggctg atgccctgaa aaaagcctgc ggccggcagg
    12241 atctcatcct gctgccgcct gtgtgcggcg tgcgcaactt cctttggaaa aaactggtgg
    12301 aactgctgga ttgcccggtg gtggaaatgc tttccatccc tccgggagtc agcggcctgc
    12361 gtctgcgcac ctgccttctg aacgccctgc gcgaactgga tgtcaccctg ctggaaaata
    12421 cgacggtgat ccgtgccgac gtcgcggacg ggcattgccg tggcgtggtc acctccggtc
    12481 tcgaccacga acacgtctat actgctgacc agatcatcgt ggctaccggc ggcttcatgg
    12541 gcgacggctt cgaggctgag cccggtaaga tgcaggaaag cattttccag ctgccgctct
    12601 gtctggaaaa tggcgagatg ccttccgccg atccttctga ctggtcggaa gaaaacgtct
    12661 ttgcccgcca tgctttcgcc accctgcgcg tccgcgtcga tgcacagctg cgtccctgct
    12721 ctgaagaagg ctcggtgctg ctggacaatg tccgttttgt gggccgctcg ctgggcggct
    12781 atgacttcgc tactgaaaaa agcggtaacg gcgtggccct ggccacggcc tggtatgccg
    12841 cccaatgtgt gtaaggcagg tgcatgatgg ctctcaaaca tcccaatcct gatgcctgta
    12901 tcgcctgcac cacctgtgtg gtacagtgcc cggtggccca ggccaccacg aacttccttg
    12961 gcccccgcat gatcggtccc gcctatgagc gcttccgcct gctgggtctt gccgaagaag
    13021 aatccctgca ctattgcgct aactgcaaga actgtgacat cgcctgcccc cagggcgtcc
    13081 cggtctccag cctgaacatg atggctcgtg ccgagcagtg ccgcaaaaag cgtccgcccc
    13141 tgcgggactg gatccttggg cacggcgaac tgatggccaa gctgctgcgc tacgtgcctg
    13201 ccaagctgaa gaacttcggc atgctcaacc ccgtgacgcg ctttgctctg gacaagctgg
    13261 gcatctctgc caaagctccc atgccggcct ttgccgaaaa gagcttccgg cagcagctga
    13321 aaaaaatctg gcagccccat accaacaagt atgtcgtcct tttccccggc tgctatctgg
    13381 atgtttacga cccgcagacc ggtctcgatc ttgtgtgggt gctgaaccag gccggctatc
    13441 atgtcatcgt tcccaaggaa ttcgtctgct gcggcctgcc catggtcgcc aacggattct
    13501 gggacgacgc ccgcgccaat gccaaaaaga atatcgcgga actgcagcgc tggcgcaagg
    13561 aaggcatccc ggtcatcacc ggttgcccca gttgcgcgtt gatgttctct tccgacctgc
    13621 cggaatacta tcccgacctg atgatcgatg gcgtctccac gactctgctg gatgctcagg
    13681 ctttcctcct ggattgcgtg gaaaagggag aactgaggct gcccgaaaaa actgtggaca
    13741 gctctgtggt tccttccgag ctcatctacc atgctccctg tcatttgcgc gctcagggca
    13801 acggcctgcc gggtctcgat ctgctccgcg ctctgcctgg catgcatgtc agcaatgccg
    13861 atgccggttg ttgcggtatc tcgggcagtt atggcttcaa gaaggaaaag tatcccatcg
    13921 gcatgcaagt gggctccgcc ctttttgatg ccgtccgcaa aagcccggcg cccgtggctg
    13981 cttctgagtg cggcacctgc cgtgtccaga tcaaacacgg ttccggcaaa gattgcatgc
    14041 atcctgtttc cgtgttgcgg cgctggctgg aagctgcccg ttagttttgg tttcggaatt
    14101 tccggagccc cccaaatata atgaagaggc ccctgcttat ggcaggggcc tcttcattat
    14161 attttatagc cgtgatgatc tttctggaat catgatcagc atacacacaa gagcttatag
    14221 cttgtgatag gatctgactc ctatgagcaa cggcttttcc tggcccgcca aaaaaggctt
    14281 gccatattag tccatataga acaaaagttt acataatcct ataggagcgt ttttcttatg
    14341 atcttaaatc ctgatttcct gaggatatac gcagaattca tggcacccga ccagaaagat
    14401 ttttatcgct gctgaagtca ttgccaaaac tccaggaatc ttgacctgcc tgccccatcc
    14461 ctcttatgca tgccagttct caggcagctg ctgtcaagcc tgcaaaaaaa tttcaacatc
    14521 tcaatatact acggtcgaag tgcccccttc ctgctgtctg gatcccgcct tttccccttc
    14581 tctgtactac tcagcccgcc ttataataat agctagtggg ccgaccagag gaaagatgca
    14641 actaagggct gaaggttgcc ataacgatat tgttatagcc tgagacgcac acctcaaagc
    14701 ggttctactc cgtaccccct cgccatccct tccatcctgg cccggcatcc ggcggcaaga
    14761 agggcccccc aaaacaaaaa aatccccggc tggtaccggg gacgatccga agcggggcac
    14821 cacagcgccc cacaggagaa agagcacaaa aaaagacccc ctcgcgctga gagctgcaag
    14881 ggggtctcga acaatctttg gcagcggcct actttcccac atgacgttat
//
