LOCUS       c00020_NZ_CALE..       23354 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CALERU010000020.1 MAG: Desulfovibrio piger isolate
            ERR318677_bin.72_CONCOCT_v1.1_MAG ERZ1764591.3, whole genome shotgun
            sequence.
ACCESSION   c00020_NZ_CALE..
VERSION     c00020_NZ_CALE..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:46:20
            Original ID  :: NZ_CALERU010000020.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 348417
            Orig. end    :: 371771
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23354
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[358417:361771]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13354
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..23354
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23354
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             450..1346
                     /locus_tag="ctg20_321"
                     /transl_table=11
                     /translation="MGRELAEARPEAMTLWKRAEAISGLPLREIYWEGDDAAMSDTRAL
                     QPALTVVNINLWRELAGKVRPCAAAGHSLGEFSALAAAEVLDPETVLQIVSLRGRLMAE
                     ADPDGTGSMAAILKMKQEDVEALAREAAVEADALLIVANYNTPAQFVVSGHRDAVALAC
                     QKAKEHRGRAIELKVSGAFHSPMMEKASRELEPLLRKAVWRKPQFPVYCNLHGRAVTDG
                     ESAKESLLKQMTSSVLWIETVRNQYADGVRRWVEVGPKAVLGKMVPACLNHLDEAARQE
                     LRVELVNSLESVENFSA"
     CDS             1377..3032
                     /locus_tag="ctg20_322"
                     /transl_table=11
                     /translation="MRATDVLRSALMGIVEEMGLNWPAKAVIEPPRDPKHGDLAANIAM
                     LLAREAHKNPHELAQVFVEKLPQRCADIEKVEVAGPGFCNVTFSQHFWRKTVCEVEAAG
                     AAYGQSSVGQGRKTLVEYVSANPTGPLHVGHGRGAAVGDSLARLLRKAGFDVETEYYIN
                     DAGRQMRILGLSVWLRVKELAGRPVEWPEDYYRGSYIIDIAREMLAEDPSLPDMEDQAG
                     QDRCYERAMNEILDGIKADLADFRVEHQHWFSEKTLVESGAVKAAFDALTEAGHTFDKD
                     GAFWFATQALGDDKDRVLRKSDGSLTYFASDIAYHHNKFQRGYDWLIDIWGADHHGYVP
                     RMRAAITAMGKPRESFDVVLIQLVNLLQGGKPVSMSTRAGTFETLADVVKEVGADAARF
                     MFLSRKSDTSLDFDLELAKQRSLDNPVYYVQYAHARICAVLRRAEERGITLPAAATDEL
                     LAALDTPEDMALLRKMAGFEDMVATAAQALAVHHVSHYLMDLAGMLHSYYAKHQVLLAD
                     DTARTLSRLALLRAVSQVLRNGLDLLGVSAPEAM"
     CDS             3038..3829
                     /locus_tag="ctg20_323"
                     /transl_table=11
                     /translation="MAQPLRKIRQRIAPSVPKGGFSFTLPPLAAGAICIVMLACIGWAF
                     FMGYMVGHGQNPGEEMRELTGIGRPDRETLAEMDKAMAGSEDASLRDKLADLGQQPVGG
                     APAAPEGDAAAAPAAASSAPAAPAAAPAAKNSHPFNKPSGNGLAAWGNAPKGAAQPAPE
                     KTAAPATRPQAATNAAPLYDFVFQVAAFRNVDDADRLRQRLEGQGLRTRGQKSGKLTLV
                     MVHMRGTDLDAANLKEELQRMRLGSPLQKSKKRVGGKPRPR"
     CDS             3848..4642
                     /locus_tag="ctg20_324"
                     /transl_table=11
                     /translation="MSSILTFCNRLGAAVLRMLDSLGAVTLFMLDGLRHIFTSPRIVPR
                     TIQQLYVIGYKSLFVILLIGIFCGMVLGLQGYYTLVQFGSVGMLGSAVSLSLIRELGPV
                     LTAIMLAGRAGSSMAAEIGVMRISDQIDALDVMDINSMAYLVSPRLVASLLAFPLLTAI
                     FDVIGIIGGYLTGVLMLHINEGAYLYRIASSVTMNDVAGGFIKSLVFGLLVATVCCHQG
                     YTTHMRRDSVGPEAVGNATTSAVVISCVLILVADYVLTSFLL"
     CDS             4649..5464
                     /locus_tag="ctg20_325"
                     /transl_table=11
                     /translation="MNAWDISFSSLSVGYGDHAVLHDINATLPGGKVSVILGGSGCGKS
                     TLLRHIIGLSRPISGNLRIGGQDLFSLPHAEARRIRRRMGVLFQDGALLGALTLVQNVC
                     LPLSEHLRLPKDVLREAGLRVLRMVGLEDFADYFPNQLSGGMRKRAGLARALIAEPRIL
                     LCDEPTSGLDPITAARMDALLQAMHRQYPEMTIVVVSHDLASLRCIADHVLVLREGRAI
                     FSGTLPELEASRDPYLLQFLRREGGDEESLADAPADPRVSAALDRWFRT"
     CDS             5646..6095
                     /locus_tag="ctg20_326"
                     /transl_table=11
                     /translation="MNSFRQTAVGIFVLLGLVCVAYLTIKLGKMEVFDSKGFELVANFN
                     SVSGLRVGADVEMAGVPVGRVASIKLDDDLSRRQARVVLILDKDLQLPADTIASVKTSG
                     LIGDKYVNLTAGGSEDILASGDTLEETESAVDIESLISKYALGGV"
     CDS             6097..6753
                     /locus_tag="ctg20_327"
                     /transl_table=11
                     /translation="MNNRRTVLGLLAGAALTLCLSLPGFAPAADAAEASPARKALEVSI
                     SRVLDCIKNPDYVNPATRPPLRRQIEDEVYHIFDFGEFSSRTVGPRWKEFSAAQKKSFS
                     NAFADLLLTTYLNKVDGYNGEQVAYTGEIANAAKTRVEVRTEITMKDGTRVPVAYRMMA
                     KDNSWRVYDIIVENLSLVKNYRTQFQDILTSGTPDELIARVKAKADEVRKQPVGK"
     CDS             6772..7605
                     /locus_tag="ctg20_328"
                     /transl_table=11
                     /translation="MRPLILVSLLLLTLLCAVPAGAAPAAPATDHAPSSLYDSSSPTMP
                     AGAISVHPYAHEQLSDGDSLDDYDCEPLTSIADPLEPWNRFWFAFNDIFFLHVAKPVYN
                     FYETVVPQPIRGGVKNFYANILMPKRMINSLLQFRVKEAFVEFGRFCMNTTVGLGGFAD
                     VAGTKKILVDIDPGGEDFGQTLGRWGIGHGFYIVWPFLGPSSVRESIGFAGDCATDVFF
                     FVHPWELATASELYLRFNALDDLLPTYESLSGIAVDPYIAVREAYIQYREARVKR"
     CDS             7742..8704
                     /locus_tag="ctg20_329"
                     /transl_table=11
                     /translation="MNLDDTLTLEQLSVSFSTDDGILPAVHAVSLSLPPAGITCLVGES
                     GCGKSLTARAILHLLPENAHISGRILFRGRDLRTMPPEEMRALRGRHIAMIFQEPMTSL
                     NPVLKVGMQTAEPLRLHLGLSRGEARQEVIRLFSEVGIPAAESRYDDYPHQLSGGMRQR
                     VMIAMALACKPDLLLADEPTTALDATIQGQILSLITEQSRKRGMAVLFITHDLGVVARI
                     ADNVGVMYAGHLVEHAPTTELFRNPLHPYTRGLMRSAPGRAAMGMNRLPAITGSVPRLD
                     NMPEGCPFAPRCDEALPRCFESVPVARCENGHSVACWAV"
     CDS             complement(9160..9762)
                     /locus_tag="ctg20_330"
                     /transl_table=11
                     /translation="VAPDTAFYDQRAASYAAASHDMDLRPLYARFLPHVRPGGLILDAG
                     CGSGRDALAFRQAGFRVEAFDASPQMARQAALLLEQDVPVLCFEDVAWQDRFDGIWACA
                     SLLHVAPADLPDALRRLQRALRPGGVMFFNFKYGQGLRRSPDGRRFTDMDEAGVRGLLE
                     ELPGLVCLEMTTGEDDRAAELRERWIQVLVRRAPSSD"
     CDS             complement(10001..11002)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_331"
                     /sec_met_domain="IlvN (E-value: 4.5e-78, bitscore: 255.2,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.1e-69, bitscore: 228.0,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVYYDQDADLSVLKNKTVAIIGYGSQGHAHAQNLRDSGVKVVVG
                     QRPGGANYELAKQHGFTPVSAAEAAAQGDLIMILLPDEVQAAVYEKDIKPNLTPGKALL
                     FAHGFNIHFNQIVPPKDVDVFLIAPKGPGHLVRRTFTEGGGVPCLVGIQQDATGEALKV
                     ALAYAKGIGGTRSGVIETSFREETETDLFGEQAVLCGGISALIKAGFETLVEAGYQPEM
                     AYFECMHEMKLIVDLMYEGGLSRMRYSISNTAEYGDYVTGPRLITDAVKKEMKAVLKDI
                     QSGKFARDFILEARANYPMFMATRRNEANHQLEQVGKELRGMMTWLKKDKKD"
     CDS             complement(11162..11650)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_332"
                     /sec_met_domain="ALS_ss_C (E-value: 1.8e-29, bitscore:
                     96.6, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQRHVLSVLVENEPGVLSRVAGLFSGRGFNIDSLNVAPTLEEGVS
                     HMTITTYGDSQILEQIMKQLHKIVTVIKVMDFADMPAIEREMMFVKVQAEGPARSEILR
                     TVEIFRCKVVDVSSSEMTIEATGDHDKLDAILSLLHRFGIKEVARTGSVAMRRSKKCE"
     CDS             complement(11663..13354)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_333"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.6e-56, bitscore:
                     185.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTGAQILLESLKKEGVDVLFGYPGGAVIDIYDELPRHPELKHV
                     LVRHEQGAVHAADGYARASGKVGCCLVTSGPGATNTVTGIATAYCDSIPLVVFTGQVPT
                     QLIGNDAFQEVDIVGITRPCTKHNFLVKDVRNLAKTIRQAFYLARSGRPGPVLVDLPKD
                     IMQARTEFVWPEDIFMRSYNPTYKPNLNQLRRTAEELAKARKPIILAGGGVIMANASEV
                     LCELAHELNIPVATTLMGLGAFPANGDLWLGMVGMHGTYAANMSINHADLLVCVGARFD
                     DRVTGRLQDFASHARIVHIDIDPTSIRKNVEVDVPVVGDCRQALEGILEICRAKMADTD
                     WSGMHADWLQTVHEWKANHPLAYNKNGHIKPQQVIETMYSITKGDAIIATEVGQNQMWA
                     AQFYTFTKPRTLLTSGGLGTMGYGFPAAIGAQFAFPDKLVINVAGDGSIQMNIQELATV
                     VQNKIPVKVVILNNGHLGMVRQWQELFYNRNYSHTNMEAQPDFVKLAEAYGAEGYRISK
                     PEELEDVLRKALTSPNPAFIDVMVEREENVYPMVPAGAALDEMLLV"
     CDS             complement(13378..13605)
                     /locus_tag="ctg20_334"
                     /transl_table=11
                     /translation="MDQHEIELIEQLLPTDPELKSLWEDHVLYSKQVEKLEAKSFRTPT
                     EEQTLKQLKKQKLEGKTKLMELLDSHRAGA"
     CDS             complement(13667..13969)
                     /locus_tag="ctg20_335"
                     /transl_table=11
                     /translation="MFFVQNVILAVVDLLAIVLNLYFWVVIVAAVLSWVRPDPYNPVVR
                     ALRTLTEPVFYRVRKWLPFTYTNGIDFSPVVVLLVIQLINRIVIASLAQFAATLV"
     CDS             complement(13972..14616)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_336"
                     /sec_met_domain="HAD_2 (E-value: 2.3e-31, bitscore: 103.9,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKLFPHGLTGIIFDCDGVMIDSRAANAIFYNKVLAALGLPPLTP
                     EQDAYTFMATARQALEYIVPPEMHQRMYEVVRTEVIYSRDIVPLLQIYPGYREFLELAR
                     SHGMRLAVHTNRTAEGMQRVLDFLALPSYFNPVVTATEAAPKPAPDGVRLILDQWGAAP
                     EQVLFVGDSPNDQKAATAAGVVFAAFGGELQGPLAAAGYDELAGLLQNEWE"
     CDS             complement(14616..15578)
                     /locus_tag="ctg20_337"
                     /transl_table=11
                     /translation="MSALCIRVPALRGPLPGEAPLLPAEGSCPVLRLWPGLPEEFSRPA
                     AGGLTASGRRAVTVAAPAPEGPWHMPEDLPFSPREAAACLDDLQRMGDAALSGQPVGTL
                     GADVGRARRNSAESALRAGLMADGTLETAQALEAAREEREKACAAQRMLLWSWLQEERL
                     AELQALSSSLSSSNARLQAALDMDPADLDEAALLAGDARDTEAALATLATLNSPVHVDD
                     SLLPAWPRLLDAVVRFAPADCLLLAEGRMRRDLLDGQGELEFRPLPDDGPLRLCDAEGR
                     IVPLLQARAPLWRILGRPRAPRCCPGWQEERPVVLRGDD"
     CDS             16016..16897
                     /locus_tag="ctg20_338"
                     /transl_table=11
                     /translation="MEQGTIRLKTGLAEMLKGGVIMDVTTPEQAKIAEEAGACAVMALE
                     RVPADIRAAGGIARMADPTIVKRIMEVVSIPVMAKARIGHFVEARILEALGVDYIDESE
                     VLTPADDRYHIDKRDFTVPFVCGCRNLGEALRRIAEGAAMIRTKGEPGTGNVVEAVRHC
                     RQVMDEIRVLCSLPEAEVANFAKENGAPLEVCMAVRKEGRLPVVNFAAGGIATPADAAM
                     MMHLGCDGVFVGSGIFKSGNPAKRARAIVQAVTNYKDYALLAEISRDLGEPMVGIDIST
                     IPPAERMQERGW"
     CDS             16899..17480
                     /locus_tag="ctg20_339"
                     /transl_table=11
                     /translation="MARIGVLALQGAFREHAAALRRLGADVCEVRQLKDMEGLEGMVIP
                     GGESTTIGKLLVEWDMLEPLRQRILDGMPVYGSCAGLILLCKEIEGSDQPRLGVLDATV
                     RRNAFGRQVDSFETDLHIDGLAGEPLRAVFIRAPLISRVGEGVQVLARLDADRGERIVA
                     VRQGNVLATSFHPELTPDLRLHQYFLDMLA"
     CDS             17831..18796
                     /locus_tag="ctg20_340"
                     /transl_table=11
                     /translation="MTNTTLTAIPGLLAGHATDDRNHTGCTAILCPQGFTPGIAVPGFA
                     PGCRETELMRPESQVDTVHGLLLAGGSAFGLAAADGVMRFLREQGHGFAMPHGVIPIVP
                     GAVIYDLDMNARPGVLPDAAMGYTAARAASAAPLTEGAVGAACGARCGRLFCLCQDDAG
                     KPLDLSDKSGLGSLCLERDGIQVAALVVLNALGNVYDGQGRFLAGGRFPDGTPVPHAQA
                     LEALAGKVPTGNTVLTVVATNVPLDKTQCSRLARMAATGLARHIVPAHMLFDGDIVFTL
                     ASKQPLPEGHGPWNELLLGALAADAVAGAVCRAARPGMFA"
     CDS             complement(19036..20235)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035:Iron-containing alcohol dehydrogenase (Score:
                     413.6; E-value: 1.9e-126)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_341"
                     /sec_met_domain="Fe-ADH (E-value: 1.3e-125, bitscore:
                     413.6, seeds: 219, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTDVKSMHMGQITSFFIPTVTLVGQNCSTQIPDRLKSLGGKKPL
                     IVTDQGIVAVGILKQITDILDAAGMQYAVYDKTVPNPTDKNVEEATEAYKSNGCDSLIT
                     LGGGSSHDCGKGVGFVVGNGGKIHDYEGVDKSSKPFPPYVAVNTTAGTASEMTRFCIIT
                     DTSRKVKMAIVDWRCTPSVAIDDPVLMMGMPPSLTAATGMDALTHAVEAYVSTAATPMT
                     DACAEKAMEYINRYLRRAVANGKDMEAREGMCYAQYLAGMAFNNASLGHVHAMAHQLGG
                     FYDLPHGECNAILLPHVCEYNLISSRRRFGRIAKLLGERVDGLSPTDASQAAIKAIRIL
                     SKDVGIPEGLIALGKKYGKEVKEEDIPTMTANAQKDACGLTNPRIMSDAAVAAIYKAAL
                     "
ORIGIN
        1 gggggatggc gggcaggccc gcgccggagc ccagatccca gcacagggga tcttcgggca
       61 ggggcaggcc ctcgaggaag gtcgccagat ggaagctgtc ggccaccagg cgctgcatgg
      121 cgtcgcgcca gtgatgcgcg cccaccaggt tcatggcctt gttccagcgg cagagcagct
      181 gcagatattc cgccagcccg ggcagggccg cctcgggcac cgtcacgccc gcctcccggg
      241 cgcatcgcgc cagggcggac agggagatgt cgtcgtgttt cgcgttgggc ttcatgggcc
      301 ttgtgtagcc tctggcggcg ggacttgcaa gctccggcgc tctgtcgtaa aaaagacgac
      361 tttataccgc ttgccaatcc atttttggag ttatgaaaat gacatcgtgt gcattgcttt
      421 ttcccggaca gggctcgcag gaagcgggca tgggccggga gctggccgaa gcccgtcccg
      481 aagccatgac gctctggaag cgcgccgaag ccatcagcgg cctgccgctg cgcgagatct
      541 actgggaagg cgatgatgcc gccatgagcg acacccgcgc cctgcagccc gcgctgaccg
      601 tggtcaacat caacctctgg cgcgagctgg cgggcaaggt gcgcccctgt gccgccgccg
      661 gtcacagcct gggcgaattc agcgccctgg ccgccgccga ggtgctggat cccgagaccg
      721 tgctgcagat cgtgtccctg cgcggccgcc tcatggccga ggccgatccc gacggcaccg
      781 gcagcatggc cgccatcctc aagatgaagc aggaagacgt ggaagccctg gcccgcgagg
      841 ccgccgtgga agccgacgcc ctgctcatcg tggccaatta caacaccccg gcgcagttcg
      901 tggtcagcgg tcaccgcgat gccgtggccc tggcctgcca gaaggccaag gaacaccgcg
      961 gccgcgccat cgagctcaag gtgagcggcg ccttccacag ccccatgatg gaaaaggcct
     1021 cccgcgagct ggagcccctg ctgcgcaagg ccgtgtggcg caagccgcag ttcccggtct
     1081 actgcaacct gcacggccgc gccgtcaccg acggtgaaag cgccaaggaa agcctgctca
     1141 agcagatgac ctcgtccgtg ctctggatcg agaccgtgcg caaccagtat gccgacggcg
     1201 tgcgccgctg ggtcgaagtg ggtcccaagg ccgtgctggg caagatggtg cccgcctgcc
     1261 tcaatcatct ggacgaggcc gcccgccagg aactgcgggt ggaactggtc aatagcctcg
     1321 aaagcgtgga aaatttttcg gcgtaggcgc gagccccgcc tcaggagata ggatacatgc
     1381 gcgctactga cgttttgcgc tctgccctca tgggcattgt ggaagagatg ggcctcaact
     1441 ggcccgccaa agcggtcatc gaaccgcccc gcgaccccaa acacggcgac ctggccgcca
     1501 acatcgccat gctgctggcc cgcgaggccc acaagaatcc ccacgaactg gcccaggtct
     1561 tcgtggaaaa gctgccccag cgctgcgccg acatcgaaaa ggtggaagtg gccggccccg
     1621 gtttctgcaa cgtgaccttc agccagcact tctggcgcaa gaccgtgtgt gaagtggaag
     1681 ccgccggcgc cgcctacggc cagagcagcg tgggccaggg ccgcaagacc ctggtggaat
     1741 acgtttccgc caaccccacc ggccccctgc acgtgggcca cggccgcggc gccgccgtgg
     1801 gcgacagcct ggcccgcctg ctgcgcaagg ccggtttcga cgtggagacc gaatactaca
     1861 tcaacgacgc cggccgtcag atgcgcatcc tgggcctttc cgtgtggctg cgcgtgaagg
     1921 aactggccgg ccggcccgtg gaatggcctg aagactacta ccgcggcagc tacatcatcg
     1981 acatcgcccg cgagatgctg gccgaagacc ccagcctgcc cgacatggaa gaccaggccg
     2041 gtcaggaccg ctgctacgaa cgcgccatga acgagatcct ggacggcatc aaggccgacc
     2101 tggccgactt ccgcgtggaa caccagcact ggttctcgga aaagaccctg gtggagagcg
     2161 gcgccgtcaa ggccgccttc gacgccctga ccgaagccgg gcacaccttc gacaaggacg
     2221 gtgccttctg gttcgccacc caggccctgg gcgacgacaa ggaccgcgtg ctgcgcaagt
     2281 ccgacggcag cctgacctat ttcgcctcgg acatcgccta ccaccacaac aagttccagc
     2341 gcggctatga ctggctcatc gacatctggg gcgccgacca ccacggctac gtgccccgca
     2401 tgcgagccgc catcaccgcc atgggcaagc cccgcgaaag cttcgacgtc gtgctcatcc
     2461 agctggtgaa cctgctccag ggcggcaagc ccgtgagcat gtccacccgc gccggcacct
     2521 tcgagaccct ggccgacgtg gtcaaggaag tgggcgccga cgcggcccgc ttcatgttcc
     2581 tttcgcgcaa gagcgacacc agcctggact tcgacctgga gctggccaag cagcgcagcc
     2641 tggacaaccc cgtgtactat gtgcagtacg cccatgcccg catctgcgcc gtgctgcgcc
     2701 gtgccgagga acgcggcatc accctgcccg ccgccgccac ggacgaactg ctggcggccc
     2761 tggacacccc cgaagacatg gccctgctgc gcaagatggc cggtttcgag gacatggtgg
     2821 ccaccgctgc ccaggccctg gccgtgcatc acgtcagcca ctacctgatg gatctggccg
     2881 gcatgctgca cagctactac gccaagcatc aggtgctgct ggccgacgat acggcccgca
     2941 ccctctcgcg tctggcgctg ctgcgcgccg tgagtcaggt gctgcgcaac ggccttgacc
     3001 tgctgggcgt gagcgctccc gaggccatgt agatcctatg gcccagcctt tgcgaaagat
     3061 ccgccagcgt atcgctccct ctgtgcccaa gggcggtttc agcttcacgc tgccgcccct
     3121 ggccgcgggg gccatctgca tcgtcatgct ggcctgcata ggctgggcct tcttcatggg
     3181 ctatatggtg gggcacggtc agaaccccgg cgaagaaatg cgggaactga ccggcatcgg
     3241 ccgtcccgac agggagaccc tggccgagat ggacaaggcc atggccggtt ccgaagacgc
     3301 gagcctgcgg gacaaactgg ccgatctggg ccagcagccc gtgggcggcg cccctgccgc
     3361 tcccgaaggg gatgccgcgg cagcccccgc cgccgcctcc agcgcccccg ccgcaccggc
     3421 cgccgctcct gccgccaaaa actcgcatcc tttcaacaag ccttcgggca acggtctcgc
     3481 ggcctggggc aatgccccca agggcgcggc ccagcccgct cccgaaaaaa cggcggcccc
     3541 ggccaccagg ccccaggcgg cgacgaacgc cgcgcccctg tacgatttcg tgttccaggt
     3601 ggcggccttc cgcaatgtgg acgatgccga ccgcctgcgc cagcgcctgg agggccaggg
     3661 cctgcgcaca cgcggccaga aaagcggcaa gctgaccctg gtcatggtcc acatgcgcgg
     3721 cacggatctg gatgccgcca acctgaaaga agagctgcaa cgcatgcggc tcggttctcc
     3781 cctgcaaaaa tccaaaaaac gggtaggcgg caaaccccgc ccccgctagt gaggcgtgat
     3841 accccttatg agcagcatcc tgacgttctg caaccggctg ggcgccgctg tgctgcgcat
     3901 gctggacagt ctgggcgccg tgaccctttt catgctcgac ggcctgcgcc atatcttcac
     3961 cagtccccgt atcgtccccc gtaccatcca gcagctgtac gtcatcggtt acaaatccct
     4021 gttcgtcatc ctgctcatcg gcatcttctg cggcatggtg ctgggcctgc aaggctacta
     4081 caccctcgtc cagttcggtt ccgtgggcat gctgggctcg gccgtctcgc tgagcctcat
     4141 ccgcgaactg ggccccgtgc tcacggccat catgctggcc ggacgcgccg ggtcctccat
     4201 ggcggccgag atcggcgtca tgcgcatctc cgatcagatc gacgccctgg acgtcatgga
     4261 catcaactcc atggcttatc tggtcagccc ccgtctggtg gcctcgctgc tggcctttcc
     4321 cctgctcacg gccatcttcg acgtcatcgg catcatcggc ggctacctga ccggcgtgct
     4381 catgctgcat atcaacgaag gcgcgtacct gtaccgcatc gccagctccg tgaccatgaa
     4441 cgacgtggcc gggggcttca tcaaatccct ggtcttcggc ctgctggtgg ccacggtctg
     4501 ctgccatcag ggctacacca cccacatgcg gcgtgacagt gtgggccccg aagccgtggg
     4561 caacgccacc acctcggccg tggtcatctc ctgcgtgctc atcctggtgg ccgactatgt
     4621 gctgacctcc ttcctgctgt aggtgaccat gaacgcctgg gacatctctt tttcttccct
     4681 ttccgtaggc tacggcgacc acgccgtgct gcatgacatc aacgccaccc tgcccggcgg
     4741 caaggtctcc gtcatcctgg ggggctccgg ctgcggcaag tccaccctgc tgcgccacat
     4801 catcggcctt tcgcgcccca tcagcggcaa cctgcgcatc ggcggccagg acctgttcag
     4861 cctgccccat gccgaggccc ggcgcatccg ccgccgcatg ggcgtgcttt tccaggacgg
     4921 tgccctgctg ggcgccctga ccctggtgca gaacgtctgc ctgcccctca gcgagcatct
     4981 gcgcctgccc aaggacgtcc tgcgcgaagc cgggctgcgc gtcctgcgca tggtggggct
     5041 ggaagacttt gccgattatt tccccaacca gctttcgggc ggcatgcgca aacgggcggg
     5101 ccttgcccgg gccctcatcg ccgagccgcg catcctgctg tgtgacgagc ccacgtccgg
     5161 tctggatccc atcacggccg cgcgcatgga tgccctgctg caggccatgc accgccagta
     5221 cccggaaatg accatcgtgg tggtcagcca tgacctggcc agcctgcgct gcatcgccga
     5281 ccatgtgctg gtgctgcgcg agggcagggc catcttttcc ggtaccctgc cagagctgga
     5341 ggccagccgg gatccgtacc tgctccagtt cctgcgccgt gaaggcggcg acgaggagag
     5401 cctggccgac gccccggccg atccgcgcgt gagcgccgcc ctggaccggt ggttcaggac
     5461 ctaggcgggg gccggcctac cctccggccc tgcggccccg tacagggacc gcgccgccgc
     5521 atccatcgtc tgagacccgg cgagccgcca acgagagttg ccgtatatcg ttgcggacgc
     5581 accttgaaga ttgcccctgc cgggcgtata accatagcgc ggcattgccg cacaaggaaa
     5641 ttgccatgaa ttctttccgc cagaccgctg tcggcatctt cgtcctgctg ggccttgtct
     5701 gtgtggccta cctgaccatc aagctcggca agatggaggt cttcgacagc aagggctttg
     5761 agcttgtggc caacttcaac tccgtttccg gtctgcgcgt gggcgccgac gtggagatgg
     5821 ccggtgtgcc cgtgggccgt gtggcctcca tcaagctgga tgacgacctt tcccggcgcc
     5881 aggcccgtgt ggtcctgatc ctggacaagg acctgcagct gcccgccgat accatcgcct
     5941 cggtcaagac cagcggcctt atcggtgaca agtacgtcaa cctgaccgcc ggcggttccg
     6001 aagacatcct ggcttccggc gacaccctgg aagagacgga atccgccgtg gacatcgaat
     6061 cccttatcag caaatacgcc ctgggaggtg tgtaatatga acaaccgtcg cacggtgctc
     6121 ggcctgctgg ccggtgccgc cctcaccctg tgtctgtccc tgcccggctt tgcccccgcc
     6181 gccgacgcgg ccgaagcctc tcccgcccgc aaggccctgg aggtctccat cagccgcgtg
     6241 ctggactgca tcaagaaccc cgactatgtg aaccccgcca cccggccgcc cctgcgccgc
     6301 cagatcgagg acgaggtcta ccatatcttc gatttcggcg agttctcgtc ccgtacggtg
     6361 ggcccccgct ggaaggaatt ctccgccgcc cagaaaaaga gcttcagcaa cgcctttgcc
     6421 gatctgctgc tgaccaccta cctgaacaag gtggacggct ataacggcga acaggtggcc
     6481 tataccggcg agatcgccaa cgccgccaag acccgtgtgg aagtccgcac cgagatcacc
     6541 atgaaggacg gcacccgcgt gcccgtggcc taccgcatga tggccaagga caacagctgg
     6601 cgcgtctatg acatcatcgt ggagaacctg agcctggtca aaaactaccg cacccagttc
     6661 caggatatcc tgaccagcgg cacccctgac gaactcatcg cccgcgtcaa ggccaaggct
     6721 gacgaagtgc gcaagcagcc ggtcggcaaa tagccgccaa acggagagag catgcgtccc
     6781 cttatcctag tctcgctcct gctgctgacg ctcctgtgcg ctgtgcccgc cggtgccgcc
     6841 ccggccgctc cggccacgga ccatgcgccg tcgagcctgt acgacagcag cagtcccacc
     6901 atgccggccg gggccatctc cgtgcacccc tatgcccacg aacagctgtc cgacggggat
     6961 tcgctggacg attacgactg tgagcccctg accagcatcg ccgacccgct ggagccctgg
     7021 aaccgcttct ggttcgcttt caacgacatc ttcttcctgc atgtcgccaa gccggtctac
     7081 aacttctacg agaccgtcgt cccccagccc atccggggcg gtgtcaaaaa cttctatgcc
     7141 aacatcctca tgcccaagcg catgatcaac agcctgctgc agttccgcgt caaggaagcc
     7201 ttcgtggaat tcgggcgctt ctgcatgaac accaccgtgg gcctgggcgg ctttgccgat
     7261 gtggccggca ccaagaagat cctggtggac atcgatcccg gtggcgagga cttcggccag
     7321 accctgggcc gctggggcat cgggcacggc ttctacatcg tctggccctt cctggggccc
     7381 agctccgtgc gtgagagcat cggctttgcg ggcgactgcg ccaccgatgt cttcttcttc
     7441 gtccatccct gggagctggc cacggcttcc gagctctacc tgcgcttcaa tgcgctggac
     7501 gacctgctgc ccacctacga aagcctgagc ggtatcgccg ttgatccgta catcgccgta
     7561 cgcgaggcct acatccagta ccgcgaggcg cgcgtcaaac gctgatccgc cgtcatcgcg
     7621 acgacatccg ggggaaggag ccgtttccgc aaggaaagac tccttccctt tttcaaacct
     7681 gccgcgccgt gcccgtcagg cacaggcccg cccaacccaa cagccgggga acacgccgcc
     7741 catgaacctg gacgataccc tcactctgga acagctttcc gtcagcttca gcaccgacga
     7801 cggcatcctg cccgccgtcc acgccgtcag cctcagcctg cccccggcgg gcatcacctg
     7861 cctggtgggc gaatccggtt gcggaaaaag cctcacggcc cgcgccatcc tgcatctgct
     7921 gcccgagaat gcccatatca gcggccgtat cctgttccgc ggccgcgacc tgcgcaccat
     7981 gcccccggaa gagatgcgcg ccctgcgggg ccgccatatc gccatgatct tccaggaacc
     8041 catgacctcg ctcaatccgg tgctgaaggt gggcatgcag accgcggagc ccctgcgcct
     8101 gcatctgggc ctgtcccgcg gcgaggcgcg acaggaggtc atccgcctgt tctccgaggt
     8161 gggcatcccc gcagcggaga gccgctatga cgattatccc caccagcttt ccggcggcat
     8221 gcgccagcgc gtgatgatcg ccatggccct ggcctgcaag ccagacctgc tgctggcgga
     8281 cgaacccacc acggccctcg acgccaccat ccaggggcag atcctcagcc tcatcacgga
     8341 gcagagccgc aagcgcggca tggccgtgct cttcatcacc cacgacctgg gcgtggtggc
     8401 ccgcatcgcc gacaatgtgg gcgtcatgta cgcggggcat ctggtggaac acgcccccac
     8461 gaccgagctg ttccgcaatc ccctgcatcc gtacacgcgc gggctcatgc gctccgcacc
     8521 gggacgcgcg gccatgggca tgaatcgcct gcccgccatc accggcagcg tcccccgcct
     8581 ggacaacatg cctgaaggct gcccctttgc cccgcgctgt gacgaagccc tgccgcgctg
     8641 cttcgagagc gtccctgtgg cccgctgcga gaacggccac agcgtggcct gctgggcggt
     8701 gtaggcgcca ttgctttttg ctgggagggg agccttccct ctgctgtcga tgcccgtaac
     8761 ttcctgcgtc gtaacgggca cgtccctgcg ggacgccatc cggtcgctcc ttgcgataaa
     8821 aaagacccat ttcccctcaa gttcccctct ttgccgccaa ggcatcaagc ccatccgccc
     8881 tgcggacggg cttttttgtt ccggtatcgt ggcggccagc tgctctatgg gcaaacaacg
     8941 ctcgcggaac gaaaggatcg acaggatatg cgggccctat ccgtcacgat gcgacccggg
     9001 aagtgggaga tgcccctgcc ctgaaacaaa aaaacaccca tagcgggtgc tttcttgttt
     9061 gatgatccca gagggcagta tttgcgaggg cacggcagga caggaaacgt catggacaga
     9121 cgctcctctc ccccatccgg tcccctcgcc aggccgatct caatcagaag acggggcgcg
     9181 ccggacaagg acctggatcc agcgttcccg cagctccgcc gcacggtcgt cctctcctgt
     9241 cgtcatctcc agacagacga gtcccggcag ctcctccagc agtccccgga caccagcttc
     9301 atccatatcg gtgaaacgac gcccgtccgg gctccggcgc aggccctgac cgtacttgaa
     9361 attgaagaac atcacgccgc cggggcgcag tgctcgctgc aggcgccgca gggcatcggg
     9421 cagatcggcc ggggccacat gcaacaggct ggcgcaggcc cagatcccat cgaaacgatc
     9481 ctgccacgcc acgtcttcga aacagagcac gggcacgtcc tgctccagca ggagcgccgc
     9541 ctgtcgggcc atctgcggtg aggcgtcgaa ggcctccacc cggaagccgg cctggcggaa
     9601 cgccagcgcg tcccgccccg atccgcaacc ggcatcgagg atgagcccgc cgggacgcac
     9661 atgcggcaaa aaacgggcat acaggggccg cagatccata tcatgggatg ccgcggcata
     9721 actggccgcg cgctggtcat agaatgccgt atccggtgcc acaggctcct ctctttatct
     9781 catcgtgtcg ggacgcaggc gctcgcttgc gggacgtgag gcctgccggg aggcagcgat
     9841 cccgacctgt cctttttccg tcaaaggtca ggggggccag tatactgctt gccccaccac
     9901 atcgccgagc cccgttttcc acaggatgcc gtcctgcccg caaaacaaaa aaagggggac
     9961 cggagtcccc cctttgtgag cgtcatgacg gacagcggaa ctagtccttc ttgtccttct
    10021 tcagccaggt catcatgccg cgcagttcct tgcccacctg ctccagctgg tggttggctt
    10081 cgttgcggcg ggtggccatg aacatgggat agttggcgcg ggcttcgagg atgaagtcac
    10141 gggcgaactt gccgctctgg atgtccttca gcacggcctt catttccttc ttcacggcgt
    10201 cggtgatcag gcgggggccg gtcacatagt cgccgtattc agccgtgttg ctgatggagt
    10261 aacgcatgcg ggacaggccg ccttcgtaca tcaggtcaac gatcagcttc atttcgtgca
    10321 tgcactcgaa gtaagccatt tcgggctggt aaccggcttc caccagggtc tcgaaaccgg
    10381 ccttgatgag ggcggagata ccgccgcaca gcacggcctg ttcgccgaag aggtcggttt
    10441 cggtctcttc gcggaagctg gtctcgataa cgccggagcg ggtgccgccg atgcccttgg
    10501 cgtaggccag ggccaccttc agggcctcac cggtggcgtc ctgctggatg cccaccaggc
    10561 agggcacgcc gccgccttcg gtgaaggtac ggcgcaccag atggccggga cccttggggg
    10621 cgatcaggaa cacgtccacg tccttgggag gcacgatctg gttgaagtgg atgttgaagc
    10681 cgtgggcgaa cagcagagcc ttgccggggg tcaggttggg cttgatgtcc ttttcgtaca
    10741 cggcggcctg cacttcgtca ggcagcagga tcatgatcag gtcgccctgg gcggcggctt
    10801 cggcagcgga cacgggggta aagccgtgct gcttggccag ctcatagttg gcaccgccgg
    10861 ggcgctggcc cacgacgacc ttcacgccgg agtcgcgcag gttctgggca tgggcatggc
    10921 cctggctgcc gtaaccgatg atggccacag tcttgttttt caagacggaa agatcggcat
    10981 cctgatcata gtaaactttc atggctcttg tccttttcaa tggaaaaata ctcggtattc
    11041 ccgaggggga aacttctatt tgggatgccg tggcgcaaat gtcaagcgtc acggcatccc
    11101 tcaggcaaat ttgccgtcat cttccggtgg gggaccgtcc gcggccccct cgccggggat
    11161 gctattcaca ctttttggag cggcgcatgg ccacggaacc ggtgcgggcc acttccttga
    11221 tgccaaagcg gtgcagcagg ctcaggatgg cgtccagctt gtcgtggtcg ccggtagcct
    11281 cgatggtcat ctcgctggag ctaacgtcca ccaccttgca gcggaagatc tccacggtac
    11341 gcaggatctc gctgcgggcg gggccttcgg cctgcacctt gacgaacatc atctcgcgtt
    11401 cgatggcggg catgtcggca aagtccatca ccttgatgac ggtcacgatc ttgtggagct
    11461 gtttcatgat ctgctccagg atctggctgt caccataggt ggtgatggtc atgtgcgaaa
    11521 cgccctcttc cagggtaggc gccacattga gcgaatcgat attgaagccg cggccgctga
    11581 acaggccggc cacgcggctg agcacaccgg gctcgttctc caccagcacg gaaagaacat
    11641 gtctttgcat ggcgtccctc ctctacacca agagcatctc atccagggca gccccggcgg
    11701 gcaccatggg atagacgttt tcctcgcgct caaccatgac gtcgatgaag gccgggttgg
    11761 gcgaggtcag ggccttgcgc agcacgtctt ccagctcttc gggcttgctg atgcggtagc
    11821 cttcggcgcc gtaggcctca gccagcttca cgaagtcggg ctgggcctcc atattggtat
    11881 ggctgtagtt gcgattgtag aagagttcct gccactggcg gaccatgccc agatggccgt
    11941 tgttgaggat gaccaccttg accgggatct tgttctgcac cacggtggcc agttcctgga
    12001 tgttcatctg gatggagccg tcaccggcca cgttgatgac caacttgtcc gggaaggcga
    12061 actgcgcgcc gatggccgcg gggaagccgt agcccatggt gcccaggcca ccgctggtca
    12121 gcagggtgcg cggtttggtg aaggtataga actgggcggc ccacatctgg ttctgcccca
    12181 cctcggtggc gatgatggca tcgcccttgg tgatggagta catggtctcg atgacctgct
    12241 ggggcttgat gtgaccgttc ttgttgtagg ccagcggatg attggccttc cattcatgca
    12301 cggtctgcag ccagtcggca tgcatgcccg accagtcggt atcggccatc ttggcgcggc
    12361 agatctccag gatgccttcc agggcctggc ggcagtcgcc caccacgggc acgtccactt
    12421 ccacgttctt gcggatggag gtggggtcga tgtcgatatg cacgatgcgc gcatgggagg
    12481 cgaagtcctg cagacggccg gtcacacggt cgtcgaagcg cgcgcccaca cagaccagca
    12541 ggtccgcatg gttgatgctc atgttggcgg cataggtacc atgcatgccc accatgccca
    12601 gccacaaatc gccgttggca gggaaggcgc ccagacccat gagcgtggtg gccacgggga
    12661 tgttcagctc gtgggccagc tcgcaaagga cttccgaagc attggccatg atgacgccgc
    12721 cgcccgccag gatgatgggc ttgcgggcct tggccagctc ttcggccgta cggcgcagct
    12781 ggttcaggtt gggcttgtag gtgggattgt aactgcgcat gaagatatct tcaggccaga
    12841 cgaattccgt acgggcctgc atgatatcct tgggcaggtc cacaaggacg ggcccggggc
    12901 gaccggagcg cgcaagatag aaggcctggc ggatggtctt ggccaggttg cgcacgtcct
    12961 tcaccagaaa attgtgtttg gtacagggac gggtgatgcc cacgatatcg acttcctgga
    13021 aggcgtcgtt accgatgagc tgcgtgggga cctgtcccgt gaagacgacc agcggaatgg
    13081 aatcacagta ggctgtggct atgcccgtaa cggtattggt ggcacccggt ccggaagtga
    13141 ccaggcagca ccctaccttg ccggaggcac gggcatagcc atcagccgcg tgcacagccc
    13201 cttgttcatg ccgcaccaga acatgtttca gttccggatg ccgcggcaac tcgtcataaa
    13261 tatcaatcac agcaccgccc ggataaccga acagtacatc aacaccttct tttttaaggg
    13321 attcaaggag aatctgcgca cctgtgagtt ccatagggtc aactcctgcg ccagcagtta
    13381 tgctccggcg cgatggctat ccaagagctc catgagcttg gttttgcctt caagtttctg
    13441 tttcttaagc tgcttcaggg tctgttcctc ggtgggggta cggaaagact tggcttccag
    13501 cttttctacc tgcttgctgt aaaggacatg gtcttcccat agggatttca gctccggatc
    13561 agtgggcagt agctgttcga tgagttcaat ttcatgctga tccataagaa atctccagcg
    13621 ttagatgttc ggcgcccacg gtggcgcccg ttacgacaaa ccgctgctac accagagtag
    13681 cggcaaactg ggccagtgaa gcgatgacga tgcggttgat gagctggatg accagcagca
    13741 ccaccacagg cgagaaatcg atgccgttgg tataggtgaa aggcaaccat ttccgcaccc
    13801 ggtagaatac cggttccgtc agggtgcgca gggcgcgcac cacagggttg taggggtcgg
    13861 ggcgtaccca cgaaagcacg gccgccacga tgacaaccca gaaatacaga ttgaggacta
    13921 tggccagcag atcgaccacg gccaggatga cattttgtac aaaaaacatg cctactccca
    13981 ttcattttgc agcagcccgg ccagttcgtc ataaccggct gccgcgagcg ggccttgcaa
    14041 ttccccgccg aatgccgcga acacgacgcc tgcggcggtg gcggctttct ggtcgttggg
    14101 actgtcgccc acaaaaagca cctgctcagg agcggccccc cactggtcaa ggatcagccg
    14161 cacaccatcg ggggcgggct tgggggctgc ttccgtcgcc gtgactacag gattaaaata
    14221 ggagggcaac gccaaaaagt ccagaaccct ttgcatccct tccgcagttc tgttggtgtg
    14281 cacggccaga cgcatgccgt gactgcgggc aagctcgagg aattcccggt aaccgggata
    14341 gatctgcagc aggggaacga tgtcgcgcga atagatgacc tccgtccgca ccacttcata
    14401 catgcgctga tgcatctcgg gaggcacgat gtattccagt gcctgccgcg ccgtggccat
    14461 gaacgtatac gcatcctgct ccggggtcag gggcggcagt cccagggccg ccagcacctt
    14521 gttgtaaaag atggcgttgg cggcgcggga atcgatcatg accccgtcac agtcgaagat
    14581 gatgccggtg aggccgtgcg ggaaaagttt gcccatcagt cgtccccgcg cagcaccacg
    14641 gggcgttctt cctgccagcc ggggcagcag cggggcgcac gcggacgccc gaggatgcgc
    14701 cacagggggg cacgcgcctg cagcaggggc acgatgcggc cttccgcatc gcacaggcgc
    14761 agggggccat cgtcgggcag gggccggaat tccagctcgc cctggccgtc cagcagatcg
    14821 cgacgcatgc ggccttcggc cagcaacagg cagtccgccg gggcaaagcg caccacggcg
    14881 tccagcaggc ggggccaggc gggcaaaagg gaatcgtcca catgcacggg gctgttgagg
    14941 gtggccagcg tggccagggc ggcttccgta tcgcgggcat cgcccgccag cagggccgcc
    15001 tcgtcaaggt cggcgggatc catgtccagc gcggcctgca gacgggcatt gctgctgctc
    15061 aggctggagc tcagggcctg gagctcggcc aggcgctctt cctgcagcca gctccagagc
    15121 agcatgcgct gggccgcaca ggccttttcc cgctcctcgc gggcggcttc cagggcctgg
    15181 gccgtctcca gggtgccgtc ggccatcagg ccggcgcgca gggcgctttc cgcgctgttg
    15241 cggcgggcac ggcccacgtc ggcgcccagg gtgcccaccg gctgaccgga aagggcggca
    15301 tcccccatgc gctggaggtc gtccagacag gccgcggctt cacgcggcga aaaaggcaga
    15361 tcctccggca tatgccacgg cccttcgggg gccggggccg cgacggtcac ggcgcgacgg
    15421 ccggatgccg tcagccctcc ggcggcagga cgggaaaatt cttccggcag gccgggccac
    15481 agacgcaaga caggacagga cccctccgcg ggcaaaagcg gtgcttctcc gggcagggga
    15541 ccgcgcaggg cggggacacg gatacagagt gcagacatgt atcatccttg gttaagctgg
    15601 agtttttagc atacgccaca gggggacacg attgcaaggc caaagccgtc attccctgac
    15661 agcttcggcc cttccctgcc tgtcccggcc ctgccagtcc tccatggcgg ccgacaaacg
    15721 tcccgcaggg gaccgctccc gttttcgata ccggcctgcc tctggcggga tcagccacaa
    15781 cggcgatgcc attccgcgga ctgtgcgcgc gggcatggaa aacagccggc gtccctgtca
    15841 gaacaggttc ccgtcccgta ttgcgcgaac ggcaggcaca gcctgtctgc cggaaaccgc
    15901 acgacgggca cggattattg tcactggcga cgatatggca tataacgcgc ttctggccgt
    15961 taacggcccc acgcaactta gcgcaccgca cgacggtgcc gaaggagtag aagatatgga
    16021 acagggcacc attcgcctga agaccggtct tgcagaaatg ctcaaggggg gcgtcatcat
    16081 ggacgtgacc acccccgaac aggcgaagat cgccgaagaa gccggcgcct gcgccgtcat
    16141 ggctcttgaa cgcgtcccgg ccgacatccg cgccgccggc ggcatcgccc gcatggccga
    16201 tcccaccatc gtcaagcgca tcatggaagt ggtgagcatc cccgtcatgg ccaaggcccg
    16261 catcggtcat ttcgtggaag cccgcatcct cgaagccctg ggcgtggact atatcgacga
    16321 gagcgaagtg ctgacccccg ccgatgaccg ttatcatatc gacaagcgcg acttcaccgt
    16381 gcctttcgtc tgcggctgcc gcaacctggg cgaagccctg cgccgcatcg ccgaaggcgc
    16441 ggccatgatc cgcaccaagg gcgaacccgg caccggcaac gtggtggaag ccgtgcgcca
    16501 ttgccgccag gtcatggacg agatccgcgt gctctgctcc ctgcccgaag ccgaagtggc
    16561 caacttcgcc aaggaaaacg gcgctcccct ggaagtctgc atggccgtgc gcaaggaagg
    16621 ccgcctgccc gtggtgaact ttgccgccgg cggcatcgcc acccccgctg acgccgccat
    16681 gatgatgcac ctgggctgcg acggcgtgtt cgtgggctcc ggcatcttca agtccggcaa
    16741 tccggccaag cgtgcccgcg ccatcgtgca ggccgtgacc aactacaagg actacgctct
    16801 gctggccgag atctcccgcg acctgggcga acccatggtg ggcatcgaca tctccaccat
    16861 cccgccggcc gaacgcatgc aggagcgggg ctggtagcat ggcccgcatc ggagtcctgg
    16921 ccctgcaggg ggccttccgc gaacatgccg cagcgctgcg ccgcctgggc gccgacgtct
    16981 gcgaagtacg ccagctcaag gacatggaag gccttgaggg catggtcatc cccggcggcg
    17041 aaagcaccac catcggcaag ctgctggtgg aatgggacat gctggaaccg ctgcgccagc
    17101 gcatcctgga cggcatgccc gtctatggca gctgcgcggg cctgatcctg ctctgcaagg
    17161 agatcgaagg ctctgaccag ccgcgtctgg gcgtgctgga cgccaccgtg cgccgcaacg
    17221 ccttcggccg tcaggtagac agcttcgaga ccgatctgca catcgacggc ctggccggcg
    17281 agcccctgcg ggccgtgttc atccgcgcac cgctcatcag ccgcgtgggc gagggcgtgc
    17341 aggtgctggc ccgtctggat gccgaccgcg gtgaacgcat cgtggccgtg cgtcagggca
    17401 atgtgctggc cacctccttc caccccgaac tgaccccgga tctgcgcctg caccagtatt
    17461 tcctggacat gctggcctga tccgccccat ctgctgaaaa aacaaagagc cccgcgccga
    17521 actttttgtc cgcgtggggc tctttgttta tatagtaccg tgccgcggca acggctgcgc
    17581 cgcgacctct tctcacacgc cccgctccct gcaaggctcc ctccctgtcc ggcatccagg
    17641 atcgccctgt ccatatgctt ctttctcccc tctccctctt cccgtcacag gacggacggg
    17701 cctgtatgcc ccgcaagaga gggctttcct tttccctccg aacatggaag attcgtctca
    17761 cggtccccct cctgatcgca gccgcatggc cgtacgggga cagctgtcaa cctccgccac
    17821 aggagctccc atgaccaata ccactctgac cgccatcccc ggcctgctgg caggccacgc
    17881 cacggacgac cgcaaccaca ccggctgcac cgccatcctt tgcccgcaag gcttcacgcc
    17941 gggcatcgcc gtgccgggct tcgccccggg ctgccgcgag accgagctca tgcggcccga
    18001 atcccaggtg gacaccgtgc acggcctgct gctggccgga ggaagcgcct ttggtctggc
    18061 cgctgccgac ggtgtcatgc gattcttgcg cgaacagggg cacggcttcg ccatgccgca
    18121 cggcgtcatc cccatcgtcc cgggagccgt catctacgat ctggacatga acgccaggcc
    18181 cggcgttctt cccgatgcgg ccatgggcta taccgcggcc cgggcggcct ctgcggcacc
    18241 gctgaccgaa ggcgctgtgg gggccgcctg cggggcccgt tgcggccgtt tgttctgtct
    18301 ttgccaggat gacgcgggca agccgctgga tctttcggac aaaagcggtc tgggcagcct
    18361 gtgtctggaa cgggacggca tacaggtagc ggccctggtg gtcctcaatg cgttgggcaa
    18421 cgtctatgat ggccaggggc gtttcctggc cggcgggcgc ttccccgacg gtacgcctgt
    18481 gccccatgcg caggccctgg aagccctggc cggaaaggtc cccaccggca ataccgtgct
    18541 caccgtcgtg gccaccaatg tccccctgga caagacccag tgcagccgtc tggcccgcat
    18601 ggccgccacc ggtctggccc ggcatatcgt ccccgcgcac atgcttttcg acggcgatat
    18661 cgtcttcacg ctggccagca agcagcccct gccggaaggg cacggcccct ggaacgagct
    18721 ccttctgggg gccctggccg ctgatgccgt ggccggggcc gtttgccgcg ccgcccggcc
    18781 ggggatgttc gcctgatgcc gaggtgatac cgccggcgcc ccttctccct gacaaacagg
    18841 ggctcccttc cctgccctcc gctttgcggt acgtcgtgca gaaaaaagct gcaaagcaca
    18901 ggggtcctgc cagcgagaca tgacgttccg ccctgtccgc acggctgccg gcaggctgac
    18961 aacgatcctg accaggaaat acaaaaaggc ccccggtttc ccgggggcct ccattatgca
    19021 gctatgcagc gaggactaca gggcggcctt gtagatggcg gccacagcgg cgtcgctcat
    19081 gatgcgcggg ttggtcagac cgcaggcgtc cttctgggcg ttggcggtca tggtggggat
    19141 gtcctcttcc ttcacttcct tgccgtactt cttgcccagg gcgatcaggc cttccgggat
    19201 gcccacgtcc ttggacagga tgcggatggc cttgatggca gcctgcgaag cgtcggtcgg
    19261 gctcaggccg tccacgcgtt cgcccagcag tttggcgatg cggccaaagc ggcggcggct
    19321 ggagatcagg ttgtactcgc acacatgggg cagcaggatg gcgttgcatt cgccgtgcgg
    19381 caggtcatag aagccgccca gctggtgagc catggcgtgc acgtgaccca ggctggcgtt
    19441 gttgaaggcc ataccggcca ggtactgggc gtagcacata ccttcgcggg cttccatatc
    19501 cttgccgttg gcaacggcgc ggcgcaggta gcggttgatg tattccatgg ccttttcagc
    19561 acaggcgtcg gtcatgggag tggcggcggt ggaaacatag gcttccacgg cgtgggtcag
    19621 ggcgtccata ccggtagcgg cggtcaggga cggaggcatg cccatcatca ggaccgggtc
    19681 gtcgatggcg acgctggggg tgcagcgcca gtcaacgatg gccatcttca ccttgcggga
    19741 ggtgtcggtg atgatgcaga aacgggtcat ttcagaggcg gtaccagcgg tggtgttcac
    19801 ggccacatag ggcgggaagg gcttgctgga tttgtccacg ccttcgtagt cgtggatctt
    19861 gccgccgttg ccgaccacga agccgacgcc cttgccgcag tcatgcgaag aaccgccgcc
    19921 cagggtgatc aggctgtcgc aaccgttgct cttgtaagct tcggtggctt cctcaacgtt
    19981 tttgtccgtg gggttgggca cggtcttgtc gtacacggca tactgcatgc cggcggcgtc
    20041 aaggatatcg gtgatctgct tcagaatgcc cacggccacg atgccctggt cggtgacgat
    20101 cagcggcttc ttgccgccga ggctcttcag gcgatcgggg atctgggtgg agcagttctg
    20161 gccgaccaga gtcacggtgg ggatgaagaa ggacgtgatc tggcccatat gcatgctctt
    20221 gacatccgtg ctcattgtgc aactccttgg tttgggcatc tgaacggtct ggatccccgt
    20281 ccgagcccgg tttggaaacg tttatggatg tactggaatc aacatacgcg accagccccg
    20341 ccatggcaat aagattttat aaaatagatt caactttttt tgtcttcccc gaaaagaacc
    20401 gggcaggccg gggcttcgcg gggctttgaa aggatgcaga tgcgcgccat gaggcgcagg
    20461 tactccttgc gtctgtcgag gaagaaggcc aagggtttcg agaagttgcg ccccagcagg
    20521 ccgtccacca ggaactgact cacctcccgt tcgcgcatca gcaccagctg ggcgctgagc
    20581 agcacggccc tgtccgcctc ggccatggag cggaccttgt gccggaaggc ctcctgggca
    20641 cgcggctggt agaaccagaa atacatcagg tccagggcgc agatgatgag gatgcgctcc
    20701 agccgctggg cctcttcgcc gccacgtccg cgcaggccgc cggggcgggc caggcagatc
    20761 agggcatcct cgcgggggaa gagcagctcc agctgggtgt agcagtcgaa gatgcgcttg
    20821 atggtgcttt cataatccca ccggcgcatg cgcaggttca cctggctgtc ggcgtaacct
    20881 tcgatgatgg cggccacggt gtccgaggcc atcttggaga tgacggccgc actgggcacc
    20941 agatacagat ggggatcggc gatgccccaa agcagcagca ggtggaagag gatgaagtcg
    21001 tacagggacg agaccgggat ggccagggcg ctgcggaaca ggttgccgat ggccgcctcg
    21061 cgggggaagc cccggtagac gttgtgcgcg aagatataga aaccattgac gatgttcagc
    21121 acggtaaaga ccaccacagg ctgctctgcc acggtcacgc cgaagcagtc ttccagcagc
    21181 cagacgcgga tcatcacctc cagcagcagc accgagatgc ccgtgtacat gagcgagtca
    21241 cagatgcgtt tgacgctgac gtgttcccgc cagtgggtca gggtgctgcg cttggcaccg
    21301 cgggcggcca tgaccatctg gaccacgttg cgcacgccgg tgatgccgaa ccagatgaag
    21361 gtgccgaacc aggccaggaa ccaccagtcc tgcgtataga tgaaggagac gaaggccggg
    21421 atgaagccca gcagcacctt gaggcagttg ctcaggttgc tgttgaggta ctggccgtcg
    21481 ggcctggctt cctccccctg cggcgcatcg gtcaggccat tgccgcggaa cgggctcagg
    21541 ccgccaagat tgaccatgtt gccccggttg ctgacgcggc aatcctcact ggccgcccgc
    21601 catacgcggc gccgctccat acccagatgg tcgcaacccg gcaaaaagcg gaaatgggcc
    21661 agcaggcgct gcccgggcga ggggttctcc ggctcgttat agcggatctg ttcctccacc
    21721 ggtgagtaga tggggatggc ggactgctgg ctgcccgact tcttcatgga cagcagggcc
    21781 cggcgcggca gcgtctcccg gatggccagg cccatgccgt acgaacggga acgactggcc
    21841 gaattgctgc ccaggcgcga cttgaggggc tcgtggcggt aggcggccca gagcttgggg
    21901 atgtcccgca ggatggcatg gaacttttcc aggcgctcgt cgtcgcccgt catctccatc
    21961 tggcggatca tctggcgcac catctgcttc atgcgcgggg caaggccctg attgagcaca
    22021 cgctgcaact cgttgatggc cgcgatattg ttgaggtgcc cttccaccca gctcttcatg
    22081 ttgaagagtt ccagatgggt gatgcgcccc tcgcagtccc agagcagctc caccacgtct
    22141 tccacgctca ggccctcggt gcccaggatc agacggttgc ccgtggcaag gccgttgaga
    22201 taggcggaaa gcttctgggc gctcatgcac atcagttccg gcaggttgtc gcacgcgccc
    22261 ggctgctccg tattggggat gcgcgggttg tggctcgggt tcagccacag ggcctgcacg
    22321 tcgtcgggcc ccagattgtc cagacgctgc aattcctcca tggcctcggg atcgtcatgc
    22381 cgggcacgca ggatctcggc ccgggcccgc aggctgggct ggatgtgctt gtgcaggtat
    22441 tcggccaggc gcagcaggga ggcatggccg cgccccacga agtcgaggaa ttcctccagg
    22501 cccatgggcg ccacggagac gccccagagc tgttccagac ggggacgctc gtcctcgttc
    22561 cagacttcca gggtgtgcag ggccacttca cgccgccagt gcagcacttc gcgccccttt
    22621 tccagcatct cccgcatctg cgggctgcgc aaaaagtcca ggaagccctt gccggagctg
    22681 aaaccgcgcg gcatccagac caggttcacg aagcggtcgt agaaaggcac gctgaactcc
    22741 aggccgatgc gcacggagat gcccacgatg cccgaggcat ggatgacctc ggtggcggcc
    22801 tccagatcca cgctgttgtc gtagaccacc gtgatggagc gcaggccctt gatccaggcg
    22861 tccatgatga ggtgcgtggg cgttttgcgg cccttggtgt tcacgtcata gacatggtcg
    22921 tcgaaggcca gctggttcca ggcttcgggc atctcgggca gatggtagcg cgccagcatg
    22981 cggcgcacca cgcgcggcgt gcccagggcg gtgctgcgga agtcatgggc cagcatgagc
    23041 tggcgggtct cgtcgccatg ggcgcgcacc atgtccttca tgatctgcat gagcgcacgg
    23101 gcggtgttgc ggcgcagggc cgaatgggcg ctggtcagca cctcgtcata cagggtctgc
    23161 agggccagca ggcggtcgcg cgagccgccg acctccaggt tgcgcagcag gttgatgacg
    23221 gcataggcca tgcgggaagc cggagaggtg accagctcct tgatgccgtg gggatgcagt
    23281 tcgggattga agagattgtc ccgcgagggc acgttgggcg cttcaaggat gcggttgacc
    23341 aggacgagga tgtc
//
