LOCUS       c00032_NZ_CYYM..       13095 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CYYM01000032.1 Dorea longicatena strain 2789STDY5608851, whole
            genome shotgun sequence.
ACCESSION   NZ_CYYM01000032
VERSION     NZ_CYYM01000032
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:31:40
            Original ID  :: NZ_CYYM01000032.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13095
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13095
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[7816:12892]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      7817..12892
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..13095
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13095
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             complement(224..943)
                     /locus_tag="ctg32_1"
                     /transl_table=11
                     /translation="MNGNVLKGGIFMNPTKEFRDYMISQGAALVGIGDLTAVPSSDYPV
                     GIAVAIPLPKHVIKDLQLAPTREYYKLYTTLNDKLNAIVTAGEKYLTGRGYQAYAQTTD
                     RITVDSDNRSPLPHKTVATRAGLGWIGKNCLLVTPQYGSAVRISSLLTDAPLTCDAPVT
                     RSQCGACHACVRYCPAHALKNTLWRSGMPREDIVSVSACYKKQREIMRKSTGIDTDLCG
                     KCFAVCTYTKQYLKQKQ"
     CDS             1024..2049
                     /locus_tag="ctg32_2"
                     /transl_table=11
                     /translation="MELMEAIQESEGQAERRVLTLLGGRYISEKALVIDGKIVWESRKN
                     GYFHGYTDEIKNITESGITYIGNEKVFCDTLGQEKQIVICGAGHVSIPVIKMAVMMDCE
                     VIVLEDRPMYADHARMAGASQVICEPFEEALDKIQGSADTYFVILTRGHRYDQICLEKI
                     AAKEHAYIGMIGSRRRTALVKQSLAEKGVDQEVLDAVYTPIGLDIGAQTPAEIGVAIIA
                     EIIEVKNRKKRTYGYSKEIMRALTAQEPYPEKKIMATIITRHGSAPQGLGTKMLIYRDG
                     RCVGTIGGGCMEARVIQIARLMAAGEGEQARICHVDMTGNEAEEEGMVCGGEVDVFLEI
                     V"
     CDS             2085..2642
                     /locus_tag="ctg32_3"
                     /transl_table=11
                     /translation="MIEVEVKIPIENIEKIKQKLLETGFIYQKTVVETDTYFTSDHYDM
                     RKKDKALRIRKTENLDTGEVKAQLNCKGPKLDQVSMTRKETEIDIYEPEKMEDILKELE
                     FYPASCRVKKTRCYYIKDHMTAAADKVENLGNFLELEIIVAKEEERAGGLDMIYELMRM
                     LGCEKTETVRDSYLSMLEKRGV"
     CDS             2817..5159
                     /locus_tag="ctg32_4"
                     /transl_table=11
                     /translation="MTLKELPIGKSATLTVVGGEGALRQHFLDMGLIPGADVTMVKYAP
                     MGDPVELRIHSYELTLRLADAEKIEITDVRDEIKIKNQIPKEKIDHPGLGEGGKYHEKA
                     DENPLPDGTTLTFALAGNQNCGKTTLFNQLTGSNQHVGNFPGVTVDRKDGVIKEHSDTL
                     VTDLPGIYSMSPYSSEEIVTRNFVLNEHPKGIINIVDATNIERNLYLTMQLMELDIPMV
                     LALNMMDEVRDNGGSILVNEMEQELGIPVIPISAAKNEGIGELIEHAVHVAKYQESPGR
                     QDFCDADDHGGAVHRCLHGIMHLIEDHAKKADIPVRFAACKLAEGDELILEQLKLDENE
                     KQLLEHIVKQMEQERGLDRSAAIADMRFTFIEKICDATVVKPKESKEHLRSAKMDKILT
                     GKYTAIPCFVAIMAAVFWLTFNVIGAALSNLLDMGISALTNLVDGALTSWNVNSVIHSL
                     VIDGIFNGVGSVLSFLPVIVTLFFFLSILEDSGYMARVAFVMDKLLRKIGLSGRSIVPM
                     LVGFGCTVPGVMASRTLPSERDRKMTILLTPFMSCSAKLPIYAFFTAAFFPKQGAVVMV
                     ALYFGGILMGILMALLLRGTMFKGEAVPFVMELPNYRMPGAKNVGQLLWEKAKDFLQRA
                     FTVIFFATIIIWFLQTFNLHMNVVADSKDSILAVVAGIIAPVFLPLGFGNWKISTALIT
                     GFMAKESVVSTLSVLFGSTAELTGAITPVAAASLLVFCLLYTPCVAAIASIKRELGAKW
                     AAYVVLGQCVVAWIAAFIVHLIGTLVM"
     CDS             complement(5229..6212)
                     /locus_tag="ctg32_5"
                     /transl_table=11
                     /translation="MEQITKVLSRISSVLTKYIGMIIICFSVIAFFWRDGFAWTTNYTS
                     IFLGVAMFGMGLTIHIGDFKVVFTRPKEIIIGFAAQYTIMPLIAWGLSVLLHLPTDIAL
                     GVILVGCCPGGTASNVITYIAGGDVALSVGMTITSTLAAPVMTPLLVYLLAGAWVQVSF
                     PGMVISVVKVVLIPVLLGILLRKLIGRHIEKLSGILPLISVVSIVMIISGIVAVNAEKI
                     MTSGFLVLCIVILHNLAGMGLGLLAGRIFHVEYDKATALAIEVGMQNSGLAITLATANF
                     AANPFATLPGAIFSIWHNISGSLFASLRRSGRYKIKEQIAKAEHVI"
     CDS             complement(6216..7055)
                     /locus_tag="ctg32_6"
                     /transl_table=11
                     /translation="MQVTNTIEKTRELVNNWKKEGKTIGLVPTMGYLHEGHASLIRRCR
                     EENDIVVVSDFVNPTQFGPNEDLEAYPRDFDRDSALCESIGADLIFCPSPAEMYHDPHA
                     FVSIDTLSDTLCGKTRPIHFKGVCTVVSKLFNIVKPNRAYFGQKDAQQLAIIRKMVLDL
                     NFDIQIVGCPIVREEDGLAKSSRNTYLSCEERKAALCLSKAVKKGQELIRNGIAASEVL
                     EPMCEIINGEPLAHIDYVSMVDALSMQPVDSVNADVLVAMAVYIGKTRLIDNFSYEV"
     CDS             complement(7162..7554)
                     /locus_tag="ctg32_7"
                     /transl_table=11
                     /translation="MTLELLKGKIHRATVVQAELDYVGSITVDEALLEAAGILEYEKVQ
                     IVDVNNGSRFETYTISGQRGSGMICLNGAAARCVSTGDKIIIMAYGQYTPDEAKEHKPA
                     VVFVDEENKVNRVTNYERHGLLKDME"
     CDS             complement(7817..8581)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: FGGY_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg32_8"
                     /sec_met_domain="FGGY_C (E-value: 1.1e-08, bitscore: 24.8,
                     seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 8.3e-51, bitscore:
                     162.7, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYIGIDIGSTASKVVVKGDHDIHFVLPTGWSSKETCQTIKDRLL
                     EDSVDVLSDDSKVVATGYGRVAVDFADHVITEITCHARGGREMAGDECAIIDVGGQDTK
                     IILVSGGMVQDFQMNDKCSAGTGKFLEIMANRLGVTLQELFDMADKGTVLPISSLCTVF
                     AESEVINYIGEGQKREDIAAGVVDSVANKVAQLAMKKNLPDKVILTGGLSNSTYFTKIL
                     SQKLGQTVSPTEHGRYAGALGAALLAKEKKKR"
     CDS             complement(8612..8872)
                     /locus_tag="ctg32_9"
                     /transl_table=11
                     /translation="MQKIQHYVLFPNHDNGMRLYGILKEAGIKTTIAPTPRVASKCCGI
                     SLLVREEDLDTIQKCIDENQIEILKIAAIERDINPKRDKYC"
     CDS             complement(8916..10193)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg32_10"
                     /sec_met_domain="HGD-D (E-value: 8.3e-92, bitscore: 298.1,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADYRKMWEELGMDVELHDQLCAVLPQAFGDVFLSQENRPDSMDY
                     YNMVVADIHGIRPAELIEHQKKGGKVFGTFCVYVPDEIVFAADAIATGLCGGSQFWVPG
                     GEKVLPANTCPLIKASVGARLDRTCPFFRIADMFIGETTCDGKKKAWEILAKDVPLHVM
                     DLPQMKRAKDIKAWAEEIETFKNVVEEFTGNVVTAEKLAESIKLINNKRKALERLYNLR
                     KNENLPISGCDVLLISQIAFYDDPARFTQMTNKLCDELDQRVKDGVSVVPAGTKRIMLT
                     GTPLAIPNWKLHNIVETSGAAIVCEEMCTGTRYFENLVDESKTTLEDQYMALAERYMKI
                     NCACFTPNEGRIDDILRLAKEYKVDGIIDVNLKFCNLYDTEGYFVEKALKESGIPVLGI
                     ETDYTDSDAGQLRTRISAFIEMLDNK"
     CDS             complement(10334..11545)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg32_11"
                     /sec_met_domain="Aminotran_5 (E-value: 4.5e-85, bitscore:
                     275.5, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEICYNIRIRYHIYHGGFSMEQNIYFDNGSTSWPKAPGVAASMTK
                     LLESGAFNINRGNYEGAYELENQVLKTRMQLARFFHAPDSRCVVFTPGITYSLNCLLKG
                     FLKPGDHVLVSSLEHNAVMRPLCQLASQDIHYTMIPAETDGTTHPESIEALIRPETKAV
                     IMLHASNVCGTILPIREIGEVCRRRHLFFAVDTAQSAGSVDIDMQKYNIDFLAFTGHKG
                     LLGPQGIGGFLISEALDQELTPLIAGGTGSQSDSLLMPDYLPDKYESGTLNLPGIIGLH
                     AALTYLDETGISAIHQKKMALTGHFLEKIREIPQAHIVGRQTLQDRLAVVSLDFPDYDN
                     AEIAFALEQDYGIMTRVGLHCAPMAHQTLHTMPQGTIRFAFSHFNTIEEIDQCIAGFRE
                     LFSV"
     CDS             11741..12892
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg32_12"
                     /sec_met_domain="HGD-D (E-value: 2.8e-87, bitscore: 283.2,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELIKELPEVFEEFAEQRQKSFLAMKGLKDQGVPVVGAYCTYFPA
                     EIARAMGAVTVGLCSVSDETIPDAEKDLPKNLCPLIKSSYGFAKTDKCPFFYFSDVVVG
                     ETTCDGKKKMYEYMSDFKDVFVMELPNTQSEMALKLWKSELIRFKEYLEKKFDVEITDE
                     AVLEAVKEENKVRKVMKDLYHVMALDPAPIKGGDLFKVLYGSGFKFDRKAIPAEIEAMR
                     EKIEKEYEEGKRLDKMPRILITGCPIGGATEKVIRAVEDNGGVVVAFENCNGAKSFDKL
                     VDEENPDVYDALARRYLNIGCSVMTPNPNRLDLLDRLIDEFKVDGVVEMTLQACHTYNV
                     ESLAIRKFVNEKKGIPYINVETDYSQADIGQLNTRIAAFIEML"
     CDS             complement(12901..13095)
                     /locus_tag="ctg32_13"
                     /transl_table=11
                     /translation="KFLSKKVDRLLTKNPLSETNVEFGFFVSSFLGQLFYLRIFNHESV
                     CTGWDLVVLFRSVTAAMMH"
ORIGIN
        1 aaaaaaatca ttaggatatt tgagtcctat agagtacaga catagacttg gattggtcac
       61 ttagatagtc caagaaaatg tccgcaccct ccactccatt tttttaatta tgtttaaatt
      121 cttcagacat tcgataccca cggaataaaa gttaggattc ctaactttta tgtaggtcca
      181 ggtagccagt ctgatgcatt aaataccaat tttattatgt atattactgt ttctgcttca
      241 aatattgctt cgtataagta cagaccgcaa agcacttccc gcacagatcc gtatcaatcc
      301 cagtactctt tcgcataatt tcccgctgct tcttataaca tgcagaaaca gatacgatat
      361 cttcgcgtgg catacccgaa cgccacaatg tatttttcag tgcatgtgcc gggcaatacc
      421 ggacgcaggc atgacaggca ccgcactgag agcgtgtaac cggagcatcg caggtcagcg
      481 gggcatcggt cagaagagaa gaaatcctta cagcagagcc atattgtggt gttacaagca
      541 gacagttttt gccgatccag ccgaggccgg ctctggtggc aacagttttg tgaggtaaag
      601 gactgcggtt gtccgagtct actgttatcc ggtctgttgt ctgggcataa gcctggtatc
      661 ctctgcctgt cagatatttt tcaccggcag ttacaatggc attcagtttg tcgttcaaag
      721 tagtatacag tttgtagtat tctctggttg gagcaagttg aagatctttg atgacatgtt
      781 tcggcaaggg aattgcgact gcaattccaa ccggatagtc agaagatgga actgcggtca
      841 gatccccaat tccgaccaaa gcagcaccct gtgagatcat ataatctctg aattcttttg
      901 tgggattcat aaaaatccct cctttcagaa catttccgtt cattgactta ttgtacattc
      961 aattttacaa tagaatgcag aagaaagata gtgggaaggg aaactattat ggaaagtaga
     1021 atgatggaat taatggaagc gattcaggaa agtgaaggac aggcagaacg cagggtgctt
     1081 actttgctgg gcggcagata catttctgaa aaggcactgg tcatagatgg aaaaattgtc
     1141 tgggaaagca ggaaaaatgg ttattttcat ggatatacag atgagataaa gaatattaca
     1201 gaaagtggaa tcacctatat tggaaatgag aaagtattct gcgatacatt gggacaggaa
     1261 aaacagattg tgatctgtgg tgccggtcat gtgtcgattc cggtgattaa aatggcagtg
     1321 atgatggact gtgaggtaat tgtactggaa gatcgtccga tgtatgcgga tcatgcaaga
     1381 atggccgggg cgtcacaggt tatctgtgaa ccattcgaag aagcactgga caagatacag
     1441 ggaagtgcgg atacgtattt tgtgatcctg acgagaggac accggtatga ccagatctgt
     1501 ctggagaaaa tagctgcaaa agagcatgcc tatatcggta tgatcggaag ccgcagaaga
     1561 acagcactgg taaaacaaag tctggcggaa aaaggcgtgg atcaggaggt gctggatgca
     1621 gtgtatacac cgatcggtct ggatatcgga gcgcagacac cggcagagat cggagtggca
     1681 attattgcag agattattga agtaaagaac aggaagaaac ggacttatgg atattccaaa
     1741 gaaattatgc gtgcgctgac tgctcaggaa ccgtatccgg aaaagaagat aatggcaacg
     1801 atcattacca gacatggttc cgcaccacag gggctgggaa ccaaaatgct gatatacaga
     1861 gatggccgct gcgttgggac gatcggcggt ggatgtatgg aagcaagagt catccagatt
     1921 gccagactta tggcagcagg agagggagaa caggcaagga tctgccatgt agacatgacc
     1981 ggaaatgaag ccgaagaaga aggtatggtc tgtggcgggg aagtggatgt atttctggaa
     2041 atcgtctaag cgcggaaaac agaatcatcg gaggcattaa aaagatgata gaagtagagg
     2101 ttaaaatacc cattgaaaat atagaaaaga taaagcaaaa attgcttgaa acagggttca
     2161 tatatcagaa aaccgttgtg gagacggata cttattttac cagtgatcac tatgatatgc
     2221 ggaagaagga caaggcactg cgcatccgta agacggagaa tctggatacg ggagaagtaa
     2281 aagcacagct taactgcaaa ggaccgaaat tagaccaggt atccatgacc aggaaagaaa
     2341 cagagattga tatctatgag ccggaaaaga tggaagacat tcttaaagaa cttgaatttt
     2401 atccagcgtc ttgcagagtg aagaagacaa gatgttatta tataaaagat catatgacag
     2461 cggctgcaga taaggtagag aatctgggca actttctgga attggagata attgttgcaa
     2521 aagaagaaga acgagcaggt ggattggata tgatatatga actaatgaga atgttgggat
     2581 gcgaaaagac agagacagta agggattcat atctgtcaat gttagaaaaa cgaggtgtct
     2641 aacatcagaa agagccataa gggacagata aagagccaaa attccccgtc cccgtggtta
     2701 gctgttgaca aaaattatcg ataagcctat actaacctta cgagttgaga aatattatca
     2761 gtaacagtgg aaataatacc actgcctgta gataaatttg gaaggaagta cagacgatga
     2821 cattaaaaga attaccgatc ggcaaaagtg caaccttgac agttgtaggt ggagaaggtg
     2881 cattgagaca gcattttctg gatatgggac ttattccggg ggcagacgtt accatggtaa
     2941 aatacgcacc aatgggtgat ccggtggaac ttcgtatcca tagttatgaa ctgacactca
     3001 ggcttgcaga tgcggaaaag atagagatta cagatgtccg tgatgagatt aagattaaga
     3061 atcagattcc gaaagagaag attgatcatc cgggacttgg agaaggtgga aaatatcatg
     3121 aaaaagcaga tgaaaatcca ctgccggatg gaacaacact gacatttgca ctggcaggaa
     3181 atcagaattg cggaaagacg acactgttca accagctgac cggctctaat cagcatgtgg
     3241 gaaatttccc gggagtgaca gttgaccgta aagatggagt gatcaaggaa cacagtgata
     3301 ccctggtgac agatctgccg ggaatctact ctatgtcgcc gtattccagt gaagagatcg
     3361 tgaccaggaa ctttgtgtta aatgagcatc caaagggaat catcaatatc gtggatgcaa
     3421 ccaatattga gcggaacctg tatctgacca tgcagctgat ggagctggat attcctatgg
     3481 ttctggcact gaatatgatg gatgaggtgc gggacaacgg cggttcgatc ctggtaaatg
     3541 agatggagca ggaacttgga ataccggtta ttccaatctc ggctgcgaag aatgaaggaa
     3601 ttggcgaact gattgagcat gccgtgcatg tggcaaaata tcaggaaagt ccggggagac
     3661 aggatttctg tgatgcagat gaccatggcg gggcagtaca cagatgcctg cacgggatca
     3721 tgcatctgat cgaggatcat gcgaagaagg cagacattcc ggtaagattt gcggcatgca
     3781 aactggcaga aggggatgaa ctgatcctgg aacagctcaa gctggatgag aatgaaaaac
     3841 agctcctgga gcatattgta aagcagatgg aacaggaacg tggacttgat cggtccgcag
     3901 caattgcaga tatgcgtttt acatttattg agaagatctg tgatgctacg gttgtgaagc
     3961 cgaaagaaag caaggaacat ctgcgaagtg cgaagatgga taagatcctg acgggaaaat
     4021 atacagctat tccatgcttt gttgcaatta tggcggctgt attctggctg acatttaatg
     4081 tgatcggagc tgcgttgtcg aatctgctgg atatgggaat ctctgcactt acgaatctgg
     4141 tagatggtgc gttgacatcc tggaatgtca attccgttat tcattcgctg gtaatcgatg
     4201 gaatctttaa tggtgtggga agtgtgttaa gtttccttcc ggttatcgtt accttattct
     4261 ttttcctgtc cattctggaa gacagcggat atatggcaag agttgcattt gtgatggata
     4321 aattactccg taagatcgga ctttccggac ggagtatcgt accgatgctg gtaggattcg
     4381 gatgtacggt tcccggtgtt atggcgagca ggacactgcc ttcggagaga gaccgtaaga
     4441 tgacgatcct tctgacacca tttatgagct gctcggcgaa actcccgatt tatgcatttt
     4501 ttacggcagc atttttccca aaacaaggag cagtagtgat ggtagcgtta tattttggtg
     4561 gaatactgat gggaattctg atggcgctgc ttttaagagg aacgatgttc aaaggtgagg
     4621 ccgtaccgtt tgtcatggaa cttccgaatt accgtatgcc gggagcaaag aatgtagggc
     4681 agcttctgtg ggaaaaagca aaggactttt tgcagagagc atttaccgta atcttctttg
     4741 caacaattat catctggttc ctgcagacat ttaacttaca catgaatgtg gtagcagatt
     4801 ccaaggacag tatcctggca gttgtggcag gaatcattgc accggtattc cttccgcttg
     4861 gtttcggaaa ctggaagatt tctactgcac tgatcacagg atttatggca aaggaaagtg
     4921 tggtatctac gctttcggta ctctttggaa gtacggcaga actgacggga gcaattacac
     4981 cggtggcagc cgcaagcctt ttggtcttct gcctgttgta tacaccatgt gttgcggcaa
     5041 ttgcatcgat caagagagaa cttggcgcaa aatgggcggc atatgtggtg ctgggacagt
     5101 gtgtggttgc gtggatcgca gcatttatcg tgcatctgat tggtacgttg gtgatgtaaa
     5161 gagtcataaa aaactcctgt ggatggaatt agatatgttc cattcacagg agttttttgc
     5221 tgcatatatt aaattacatg ctctgctttt gctatttgtt cttttatctt atatcttccg
     5281 ctgcgccgga gacttgcgaa taaagagccc gaaatattgt gccatatact gaagatcgcc
     5341 ccaggcagtg tggcaaatgg gtttgcggca aagtttgcgg tggcaagtgt gatagcaaga
     5401 ccgctgttct gcataccgac ttcgatcgca agggcggttg ctttgtcata ttccacatgg
     5461 aagatgcgtc cggcaagtaa tccaagtccc atacctgcaa gattatgtaa gataacgata
     5521 cagagtacga ggaatccgga tgtcatgatc ttttccgcat ttactgcgac gattccgctg
     5581 atgatcatga cgatggatac aacggagatc agtggaagga tgccggataa tttctcaata
     5641 tgtctgccga tcagtttgcg gagaaggata cccagaagaa ccgggatcag tacgaccttt
     5701 acaaccgaga ttaccatccc cgggaaagat acctgaaccc atgcaccggc aagtaaatat
     5761 accagaagag gtgtcataac cggtgctgcc agagttgaag tgatcgtcat accgacagaa
     5821 agtgcaacat caccacctgc gatataagtg atcacattgc tggcagttcc accagggcag
     5881 catccgacca ggatgacacc aagtgcgata tccgttggca gatgaaggag gaccgagagt
     5941 ccccatgcga tcagcggcat aatcgtatat tgtgcggcaa atccgataat gatctctttg
     6001 ggtctggtaa ataccacttt aaaatctccg atatgaatcg tcagtcccat gccgaacatg
     6061 gcaacgccga gaaagatcga agtatagttt gtagtccatg caaatccatc acgccagaag
     6121 aaggcaatga cagaaaagca gataatgatc attccaatat atttggtaag aacagagctg
     6181 atccgtgata atacctttgt tatctgctcc atatattata cctcgtaact gaaattgtcg
     6241 atgagtcggg tctttccgat ataaactgcc atagcaacca ggacgtcagc atttacagag
     6301 tcaacaggct gcatgctgag tgcatcgacc atggatacgt aatcgatatg tgccagcggt
     6361 tcaccgttta tgatctcaca catcggttct aatacttcag atgcggcaat accatttcgg
     6421 atcagttcct gacctttctt tacagctttt gaaaggcaga gggcagcttt gcgttcttcg
     6481 cagcttaagt atgtattacg ggaagatttg gcaagtccgt cttcttcacg tacgatcggg
     6541 catccgacaa tctggatatc aaagttcaga tccagaacca ttttgcggat gatagcaagc
     6601 tgctgtgcat ctttctgtcc aaagtaagca cggtttggtt ttacgatgtt aaataacttt
     6661 gatacaacgg tacacacccc tttgaaatgg atcggacgcg tcttaccgca cagcgtatca
     6721 gataaagtat cgatactgac aaatgcgtgt ggatcatgat acatttccgc cggtgacgga
     6781 cagaagatca gatctgctcc gatgctttca caaagtgcac tgtcgcggtc aaagtctctt
     6841 ggataagctt ccagatcttc attcggtcca aactgtgtcg gattgacgaa atcagataca
     6901 acaacgatat cattttcctc gcggcagcga cggatcagac tggcatgtcc ctcatggaga
     6961 tatcccatag tagggacaag accgatggtc ttaccttctt tcttccagtt atttacgagt
     7021 tctcttgttt tttcaattgt gttagttacc tgcattggta ttctccttta ttcgttataa
     7081 ttcggagagt tctcttctga atacactgtg atctctggtg attgcatgta ataaaatatg
     7141 ttgtgataat tgagtatctt tttattccat gtcttttaac agtccgtgac gttcataatt
     7201 ggtcacgcgg tttaccttgt tctcctcatc tacgaataca accgcaggtt tgtgttcttt
     7261 tgcttcgtcc ggcgtatact gtccgtaagc catgatgatg atcttatctc cggtactgac
     7321 acatcttgca gcagctccgt ttaagcagat cattccactg ccacgctgtc cgctgatggt
     7381 gtacgtttcg aaacggcttc cgttgtttac atcaacgatc tggactttct catattcgag
     7441 aattccagca gcctccagta atgcttcatc caccgtaatg cttcctacat aatcaagttc
     7501 tgcctgaacg acagtagcgc ggtggatctt tccttttaat aattcaagtg tcatctcata
     7561 tatcctttcc ttttaaggaa aaaaattcag ccagaataca tctggtcctg agtcttattt
     7621 cctgaaaata taagctcatt tttgttgaaa attatgagat tccagtgctt cagttctgag
     7681 tatggttctg tcagggacag ataccgtctc cgctgttcat tataaaaagg cagaaaaggt
     7741 atgtcaatct atgtatacga aaaaaaaaca gaaccggatt tctgaaatta taaatccggt
     7801 tctgtattat ttcttattat ctttttttct tttcctttgc aaggagtgcg gcaccaagtg
     7861 cacctgcata tcttccatgt tcggtaggag atacggtctg tccgagtttc tgtgagagaa
     7921 tcttcgtgaa gtaggtgctg ttactgagtc cgccagtcag gattacttta tccggcaggt
     7981 ttttcttcat ggcaagttgt gctaccttgt tggcaacaga atcgacaaca ccggcggcaa
     8041 tatcttcccg tttctgtccc tcaccgatat agttgatgac ctcagattcg gcaaataccg
     8101 tacacagtga actgatcgga agaacagttc ctttatctgc catatcaaac agttcctgca
     8161 gggtaacgcc taagcggttt gccataatct ccagaaattt tccggttccg gcagaacact
     8221 tatcattcat ctggaagtcc tgtaccatgc cgccggacac caggatgatc ttggtatcct
     8281 gtccgccgac atcgataatg gcacattcat ctccggccat ctcccggccg cctcttgcat
     8341 ggcaggtaat ctccgtgata acatgatctg caaaatctac agcaacacgg ccatatccgg
     8401 ttgcgaccac ttttgaatcg tccgacagta catctacact gtcttccagt agacgatcct
     8461 tgatcgtctg gcaggtttcc ttgctgctcc atccggttgg cagtacaaaa tgtatatcat
     8521 gatctccttt tacaacgact ttggatgccg tagatccgat atcaattcca atataatcca
     8581 taataaaatt tcctcgtttc acatatattt tttaacaata tttatcccgc ttcgggttga
     8641 tatcccgttc aatggcggca atttttaata tttcgatctg attctcgtcg atgcatttct
     8701 ggatcgtatc caggtcttct tctctaacga gcagtgagat gccgcagcat ttactggcca
     8761 cgcgcggtgt aggagcgata gtggtcttga ttccggcttc ttttaatatc ccatacagac
     8821 gcattccgtt gtcatggttg ggaaataata cataatgctg tatcttttgc atgatctgtt
     8881 acctcggtta tgtatcggac atgaattgtc tgatattatt tgttatctaa catttcgata
     8941 aatgcactga ttctggtacg aagttgtcct gcatcgctgt cggtgtaatc ggtctcgatt
     9001 ccaaggacag ggattccgga ttctttcagt gctttctcta cgaaatagcc ttcggtatca
     9061 taaaggttac agaacttgag gttcacatcg atgataccgt caactttgta ttccttagca
     9121 agacgtaaga tgtcatcaat acggccttca tttggtgtaa agcatgcgca gttgatcttc
     9181 atgtatcttt cagccagagc catatactgg tcttccagtg ttgtcttgct ttcatcgaca
     9241 agattttcaa aatatctggt tccggtacac atctcttcac agacgattgc agcaccactg
     9301 gtctctacaa tattatgaag cttccagttc ggaattgcaa gaggagttcc ggtcagcatg
     9361 atacgtttgg ttccggcagg aacaacgctt acaccgtctt ttactctctg atccagttcg
     9421 tcacataact tattcgtcat ctgtgtaaat cttgcaggat catcatagaa tgcaatctga
     9481 gagatcagaa gtacatcaca tccgctgatt ggaagattct cattcttacg aagattgtaa
     9541 agacgctcca gagcttttcg tttattgtta attaatttaa tactttcggc cagtttttcg
     9601 gcagtgacta catttcctgt aaattcttct acgacatttt taaatgtctc aatttcttct
     9661 gcccatgcct tgatgtcttt ggcacgtttc atttgaggaa ggtccatcac atgtaacggt
     9721 acgtctttgg caagaatctc ccatgctttc ttcttgccgt cgcaggtggt ctccccgatg
     9781 aacatatctg cgatacggaa gaatggacag gtgcggtcaa gacgtgcacc aacagatgcc
     9841 ttgatcagtg gacaggtatt ggcaggaagg actttctctc cgccaggaac ccagaactgg
     9901 gaaccgccgc ataatccggt tgcaatcgca tctgccgcaa atacgatctc gtccggtaca
     9961 tatacacaga atgtgccgaa gactttgccg ccttttttct gatgctcgat cagttctgca
    10021 gggcggatac cgtgaatatc tgcaactacc atattataat agtccataga atccggacgg
    10081 ttttcctgcg ataaaaatac atctccaaat gcctgtggaa gtactgcaca gagctggtca
    10141 tgcagttcta catccattcc gagttcttcc cacattttac gataatcagc cattttaaaa
    10201 tacctcctta tagtgtaatt gatccaattg tatcgataag ttaaacgtaa cacttttagg
    10261 gggcccaggc aatgcatacc ggaagaattg gctatagata atttacaagt tcaatagaat
    10321 atatctatag attctatact gagaacagtt ctcgaaatcc agcgatgcac tggtcgattt
    10381 cttcgatggt attaaagtgg ctgaaagcaa aacgtatcgt tccctgaggc attgtatgca
    10441 gggtctgatg cgccatcggg gcacagtgga gtccgaccct tgtcataatt ccataatcct
    10501 gttccagagc aaatgcaatc tctgcattgt catagtccgg gaaatcaaga gagacgacag
    10561 caagccggtc ctgaagggtc tgccttccca caatatgtgc ctgtggaatt tcacgtattt
    10621 tttcaagaaa atgtccggtc agtgccattt tcttctgatg gattgcggaa atcccggttt
    10681 cgtccagata agtgagggca gcgtgaagtc cgatgatgcc agggagattt aatgtgccgc
    10741 tttcatactt gtccgggaga tagtccggca taagaagcga atccgactgg cttccggtcc
    10801 cgcctgcaat cagaggtgtc agttcctgat ccagagcttc tgagatcaga aagccgccga
    10861 taccctgcgg gccaagcagt cccttatgtc cggtaaatgc aagaaagtcg atgttatatt
    10921 tctgcatatc gatatcgaca gaaccggcac tctgtgcagt gtccacggca aagaacagat
    10981 gacggcgcct gcatacctca ccaatctcac ggattggcag aatggttccg catacattgg
    11041 aagcgtggag catgatgact gcttttgtct ccggacggat cagagcttcg atcgattccg
    11101 gatgcgttgt gccgtctgtc tctgcaggaa tcatcgtata atggatatcc tgtgaagcaa
    11161 gctgacagag cggacgcatc acggcattgt gttccagact gctgaccagc acgtggtcgc
    11221 cgggctttaa aaatcctttg agcagacaat tcagagaata ggtgatcccc ggtgtaaata
    11281 cgacacatct ggaatccggt gcatgaaaaa atctggcgag ctgcatgcgg gtcttaagta
    11341 cctgattttc aagttcgtag gcaccttcgt aatttccccg gttaatattg aaggcaccgg
    11401 attctaaaag tttcgtcatg gaagcagcga ctcccggtgc tttcggccag gatgtgctgc
    11461 cgttgtcaaa atatatgttc tgttccatag aaaaacctcc atgataaata tggtatctga
    11521 tacgtatatt gtaacagatt tccatattaa cgtatacagg agatgaagtc aggaaaagga
    11581 tagaaaatgc gaataatatt catagacgat attaatagaa tggaacgatt tatcaatatt
    11641 tcctattatg taaatacagg tacaggtggt atgatagtct tatgaaaaaa attatcaaaa
    11701 aaattatcaa aaaataaaaa aagcacggag gaaatttatt atggagttaa ttaaagaact
    11761 gccggaggta ttcgaagaat ttgcagaaca gcgtcagaaa tcattcctgg caatgaaggg
    11821 gttaaaagac cagggagttc cggttgttgg cgcatattgt acttattttc cggcagagat
    11881 cgcaagagca atgggagcag ttacagtcgg cttatgctct gtatccgatg agacaatccc
    11941 ggacgcagag aaagacctgc caaagaactt atgtccactg atcaaatcca gctatggatt
    12001 tgccaagaca gacaaatgtc cattcttcta cttctcagat gtagttgttg gggagactac
    12061 ctgtgacgga aagaagaaaa tgtacgagta tatgtcagat ttcaaagatg tattcgtaat
    12121 ggaactgcca aatacacaga gcgagatggc cctgaaactc tggaagagtg aactgattcg
    12181 tttcaaagaa tatctggaga aaaaattcga cgtagagatc acagatgaag ctgtattaga
    12241 ggccgtaaaa gaagaaaata aagtaagaaa agtcatgaaa gacctgtatc atgtcatggc
    12301 acttgatcct gcaccgatca aaggcggcga cctgttcaaa gtattatacg gaagcggctt
    12361 caaattcgat cgtaaagcaa tcccggcaga gattgaagcc atgagagaga agattgaaaa
    12421 agaatacgaa gaaggtaaga gactggacaa gatgcctcgt atcctgatca ccggatgtcc
    12481 gatcggcgga gcaactgaga aagtgatccg cgccgtagaa gacaatggtg gagttgtagt
    12541 tgcattcgaa aactgtaacg gagcaaaatc ttttgacaaa ttagtagacg aagagaatcc
    12601 ggatgtatac gatgcactgg caagacgtta cctgaacatt ggctgttctg taatgacacc
    12661 gaatccaaac agactggacc ttctggatcg cctgatcgat gaatttaagg tagacggagt
    12721 tgtcgagatg acacttcagg cttgtcatac atataatgta gagtcactgg ctatccgtaa
    12781 atttgtgaat gagaagaagg gtattccgta cattaatgta gagacggatt attcgcaggc
    12841 tgatatcggg cagttgaata ctcgaattgc ggcatttata gagatgctgt aaatttctat
    12901 ttaatgcatc atggcggctg tcaccgaccg gaataaaact acaaggtccc agcctgtgca
    12961 tacggactca tggttgaaaa ttcttaagta aaaaagttga cctaaaaacg agctcacaaa
    13021 aaatccaaac tcgacattcg tctcagacag tggatttttt gtgagcaaac ggtcaacttt
    13081 tttacttaag aattt
//
