LOCUS       c00004_NZ_AENN..       29903 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_AENN01000017.1 Eremococcus coleocola ACS-139-V-Col8 contig00010,
            whole genome shotgun sequence.
ACCESSION   NZ_AENN01000017
VERSION     NZ_AENN01000017
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 01:05:49
            Original ID  :: NZ_AENN01000017.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 70330
            Orig. end    :: 100233
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..29903
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[80330:90233]"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..19903
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
     cand_cluster    1..29903
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /kind="single"
                     /product="acetate2butyrate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..29903
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="acetate2butyrate"
                     /region_number="1"
                     /rules="(not (POR or POR_N or PFOR_II) and minimum(4,
                     [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF, ETF_alpha,
                     HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and minimum(1,
                     [EC1_2-faecali, ECH1_Enoyl_CoA_DH1, ECH1_Enoyl_CoA_DH2,
                     ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4, Thiolase_C]))"
                     /tool="gutsmash"
     CDS             complement(2527..3657)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OAD_beta"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_89"
                     /sec_met_domain="OAD_beta (E-value: 5.6e-157, bitscore:
                     516.2, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVLINFWQSTGLASLTMQAVIMIVLACTFLYLAIAKGYEPYLLI
                     PIASGMLLVNLPVTGLMEEGGLFYYLYQGTKLGIYPPLIFLCVGASTDFGPLIANPKSI
                     FLGAAAQFGIFFTFIGAFLLNDFIPGIHFTPQEAASVAIIGGADGPTALYLTSQLAPHI
                     LGAIAIAAYSYMALVPIIQPPIMKALTTEAERQVKMDQLRPVSKREKIIFPIVVIIFTV
                     LLLPSAAALIGMLMLGNLIKESGVVPKLTSVLTDTFMYIITILLGLTVGATAKGEVFLT
                     AQTLSIVVLGLVAFSVGTASGVLFGKLMYRLSGGKINPLIGSAGVSAVPMAARVSQKVG
                     QSVNPANFLLMHAMGPNVAGVIGSAVAAGLLLNFFQ"
     CDS             complement(3680..4072)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 70.1; E-value:
                     3.5e-22)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_90"
                     /sec_met_domain="Biotin_lipoyl (E-value: 1.5e-21, bitscore:
                     70.1, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKKYKVRIDHQEYEVEIEEVAEIEASQEAKPQPSRSLRPSQPLK
                     PASPAKRPKDPEASGSEVISAPMPGTVLSLQVKMGDQVEAGKVLLVLEAMKMENEIVAP
                     QAGKVVEIHTSQGLAVNTGDLLISLA"
     CDS             complement(4075..4449)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OAD_gamma"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_91"
                     /sec_met_domain="OAD_gamma (E-value: 3.6e-14, bitscore:
                     47.2, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVNDGVSLFESIYITIFSMAMVFLTLMVIALILSAFKYLGTKQV
                     NTQADPSIPAKNQTQSDLVSANHLETKQVAAIVAAIQAYRGQDSHPFRVHKIRRSQHDY
                     NIWAMAGLQENTRPISSRED"
     CDS             complement(4463..6010)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CT_Vparvula"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_92"
                     /sec_met_domain="CT_Vparvula (E-value: 4.5e-259, bitscore:
                     854.0, seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VANDKLKELDSKKVAAQQAGGSKGIGKQHAKGKYTARERLDKLFD
                     ANSFVELDTFVQHRCEQFGLDQDRPLGDGVVTGYGTIDGRLVYCFAQDFTVMGGSLGQM
                     HAAKIVKVQELAQKVGVPLIGINDSGGARIQEGVDSLAGFGDIFFNNVMASGQIPQISV
                     IMGPCAGGAVYSPALTDFILMVDQSSNMFITGPQVVKTVTGEVVTAEALGGATTHNQSS
                     GVAHFVDVDEEAALARIRKLLSFLPANNLELAPRVAVSDDLNRLDLRLDEIIPASPNKP
                     YDIHQVIESLLDEGDFFEVQALFAKNIVIGFGRMGGQTVGIVANQPNNLAGCLDINASD
                     KAARFIRTCDAFNIPLLTLVDVPGFLPGTSQEYNGIIRHGAKLLYAYSEATVPKITVIL
                     RKAYGGAYIAMCSKHLKADLVYAWPTAEIAVMGPDGAANIIFKHDIEAALDPDQMRADK
                     IRDYRQAVANPYTAAARGYVDDVVQPSTSRQRLISAFDMLAGKREGRPAKKHGNLPL"
     CDS             complement(6279..6965)
                     /locus_tag="ctg4_93"
                     /transl_table=11
                     /translation="MKQDNIISKTLASIKGLDQRPSQVDLIPRLSAYIADWFFGNLFVM
                     AGPFVMFSLMTAKEASYKNLYSFPAYGLAETWSYLSFILALIFYSLYFVFIPYKVWPGQ
                     TLGKKMTKLKIVEAEDYETTSWQALLMRHLVGFVVVEGAAFTMGQYLQETLSLMTGFYT
                     ENYLGTAGLILAMVSLILVIFTRSGRALHDYMANTRVIKIEGEEPVKKLIRDQRRRNHQ
                     LRHLKK"
     CDS             complement(6991..7998)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M22"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_94"
                     /sec_met_domain="Peptidase_M22 (E-value: 3.8e-97, bitscore:
                     319.3, seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVILAIESSCDETSVALIEDGHKILTNLVASQIKSHMRFGGVVP
                     EVASRHHVEQISQLVNLALKEGKVNWKQIDAVAVTQGPGLVGALLVGVTAAKTLALIHN
                     KPLIAVNHLAGHIYASQLQAPLQFPALALIVSGGHTELVYLENHLDFQVIGETQDDAVG
                     EAYDKVGRILDLPYPAGKYLDQLAHQGQESYDVPRAMLHEDNLDFSFSGMKSAVMNLVH
                     NAHQRGQTINQADLAASFQAAVVEILTSKVKTALEDHPNCQQFILAGGVAANSGLRAAL
                     TDLIQTNFSQIDLQIPPLSLCGDNAAMIGAVAYPMYLAKDFADLSINAIPSLDL"
     CDS             complement(8036..8494)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_95"
                     /sec_met_domain="Acetyltransf_1 (E-value: 5.5e-14,
                     bitscore: 46.5, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWFEILASQDLTADQQTFVAEQNQSLGWTLKASQADFTLSYSYYA
                     CLVSQAGVSEFIAYIAYHHLFEDITINQVWVAPECRGQGIGSRLLQDWLASLPSTSRVT
                     LEVRQGNQAARALYTKYNFKVIDQRPAYYHDPREDAIIMQWCISEGIF"
     CDS             complement(8509..9114)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_10"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_96"
                     /sec_met_domain="Acetyltransf_10 (E-value: 1.1e-13,
                     bitscore: 45.3, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHLLTTIKQLIKPSQPKGQPRNHQLLHTLAPLIKQGQVTISQNP
                     AWQAFDLQWQPIAAHDIAAYTELEASAYNGYLAWKEADFQTDFARNPYCLYLVLVDQDD
                     QMVAGISGRLQARSAHISHVMVVPNFRGYGLGLFMVQEFLAYADYLQISKTELEVRVSN
                     QIALNLYQKLGFKIDHLKKHYYFDNFEDGYAMVRLLPE"
     CDS             complement(9077..9883)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M22"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_97"
                     /sec_met_domain="Peptidase_M22 (E-value: 3.6e-23, bitscore:
                     76.7, seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRWLGVDSSTDALSLVLGQGELTNNFSDSKVIASQFNKENKQHG
                     QSLVASVQALLAEVSWTVADIEAVVVGIGPGSYTGLRIGVTFAKVWATSLAVPLYEVSS
                     LALQISSAPIAPVIISLMDARRLSAYIGLYSHNPINNRLENLQADCHGDFKEWLQSETV
                     SQILNDTSQVLIVGHDTESFIQVFQEIYSKIELDTVTTEEALPHVERVFNLSMVGQLNR
                     CTDPHTLAPNYAHATLAEQNWAQDHQRRVASRAENEAFIDHYKTTN"
     CDS             complement(10001..10789)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: EC1_2-faecali"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_98"
                     /sec_met_domain="EC1_2-faecali (E-value: 1e-76, bitscore:
                     251.6, seeds: 67, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEYKNILFDVKNQIGTLTINRPKALNALNSETLNEIYDLVKAIE
                     GGQFEIHFLIITGAGDKAFVAGADIKEMANLNPLEARDFSRLGSQVFKAIQNLSLPTLA
                     AINGYALGGGLELSMACDLRFACENAVVGLPEVGLGVIPGFGGTQRLPRIIGLAKANEF
                     LFTGGNLKADVALEAGLFNRLYPVEQLLPEAYAYAEKVIKKAPIAVRYAKLAASKGIDM
                     SLDKGLDYESELFGLLFATEDQSEGMGAFVEKREAEFKNQ"
     CDS             complement(10803..11654)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_99"
                     /sec_met_domain="HCDH (E-value: 3.4e-38, bitscore: 124.3,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH_N (E-value: 6.6e-66, bitscore: 215.7,
                     seeds: 60, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIKKIMVIGSGQMGNGIAQVSAQAGYEVILNDMKEEFAEKGLAN
                     IIKNLSRDVDKGRKSEEEKQTILDRITLSTDKQDAKDCQLIIEAAVENFEIKKSIFKEL
                     NGIVGEDVILATNTSSLPITDLAAVVSKPQRFIGMHFMNPVPVMKLVEIIRGVETSDEV
                     YQVIEDLSREMTKDPVEVNDSYGFVSNRVLMPMINEAAFTLYESVATPEAIDQVMELGM
                     NHPMGPLKLADLIGLDTCLSIMNVLYEGFNDPKYRPCPLLKKYVAAGRLGKKSGQGFYK
                     YD"
     CDS             complement(11702..12889)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Thiolase_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Thiolase_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_100"
                     /sec_met_domain="Thiolase_N (E-value: 1.1e-90, bitscore:
                     297.5, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="Thiolase_C (E-value: 5.4e-46, bitscore:
                     149.3, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHSVILSGVRTPFGRFGGMLKDIKAVDLGAEVIKAAVEKAGVDK
                     ENIEYVVFGQVLQAGVGQIPSRQASIKAGLDWSVGSETINKVCASSFRAVTLADQMIRC
                     GDKDLIVAGGMESMSNTPFASKDMRWGHRMFNSEFIDLMVYDGLWDAFYNQHMAVNGGY
                     GADEYDISRQAQDEWAYQSQMRAVQAQEAGRLDEEIIPLTIPQGKKDPITVSKDETPRP
                     DTNLEKLSRMPGLFVDGNTVTAGNAPATNDGASALVIASEDKAKEMGLKPLATILDHEE
                     VGVETRLIASAPGHAIKNLLDRNNLRVDDIDLFEINEAFAAVTLVSQKMNNIPSEKINV
                     NGGAIAFGHPIGASGGRIIATLVHEMRRRKAKYGVAAICSGAAQGDAILIQCDYD"
     CDS             12994..13902
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     56.8; E-value: 5.5e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg4_101"
                     /sec_met_domain="LysR_substrate (E-value: 9.6e-36,
                     bitscore: 117.1, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 2.4e-17, bitscore: 56.8,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDWKSINFQHLNYFLIAAKYQNYSQAADELFINYSTLSKAIAGIE
                     NQLGVKLFEKDGRNIKLTKYGKILNASVYAAMTNIEDGLDEIARFSHPDHGQVNISSIY
                     TVSAKYLPRLLSRFRNLFPELSLDITQASTQQIIDHVLDGTRDIGFCGEFDYSSYSSEL
                     NREFIYNDEIVLIVPANHRFAARKSVSFAEIKNEQFIGWNASAGMYYAIQQAINRVAGP
                     NFKLNTIYSMNEDTGVVGMVRAGLGIAFSSKNTELNYDDIRILELTDLYIIYNVYMIWA
                     NSEFTPSSLKSFKDFIIAQIN"
     CDS             14370..15290
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_102"
                     /sec_met_domain="LysR_substrate (E-value: 7.4e-29,
                     bitscore: 94.6, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 6e-13, bitscore: 42.7,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIKQINYFLEIVASDFNISSASKKLFISQSTLSQSMIQFENDYQ
                     AQLFKREKGRLIGLTDLGQAMYKYAQEIQKLHQEMMQVIDQDKKETTQIVRIGIPPILV
                     RTRFPRFLLNMKQLYPDLRIEYIEEGCQRLCQLLENKEIDIAFLTDPLPTTKLLNSKTA
                     IKDEFVLFMDKNHPLTKQNQVKWSSLNQYSSAIFTDAYSTHHFFMIQCQKERIAPKIFL
                     ESNSWEYLIDTIKNSQLITFLPKSVYPMVNRRQITYRPFERSANFKIFISTTDEIYQSA
                     IKKCVYDALIDYCSQVEAVANLSLA"
     CDS             15679..16503
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: EC1_2-faecali"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_103"
                     /sec_met_domain="EC1_2-faecali (E-value: 3.6e-74, bitscore:
                     243.3, seeds: 67, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKCKRLSFYKGGITLKELATLTLNIEDTLAFLNLNAVKSLNAINS
                     AMLDDLNEAMDLLEADPNVKVLVITGNGKAFMAGGDIKEMMDLSPEEADHFIAYGNQTM
                     NRIMNLSLVTIAAVNGFALGGGLELALTCDIRIGTTANKIGFPEVGLGIIPGYGGTQRA
                     SRLIGIGQTKRLALSGEIIDGAEAHRIGLLEKIVEPDQLIEEATKFAKQIAKNAPIAIK
                     QAKLSINFGSQSTLENGLKLEGEIVKGLFRTEDKYEGMNAFVEKRKAEFKGK"
     CDS             16531..17739
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_104"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.5e-29, bitscore:
                     97.2, seeds: 49, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 5.1e-24, bitscore:
                     78.5, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 3.1e-10, bitscore:
                     34.8, seeds: 796, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKSKIEKLQYLYPEDIYGYSHDLSENEVDFLLKLRETLEKELYP
                     VIDDHWKKELFPMEAFKKITDLGIMTDPSLFEGRENKLKTSEIFNLFRLYELNRMDSSI
                     GAFTIVHGGLAYSTVLIGGSQEQIDYYAPKLASYEWHSCFGLTEPLHGSDIAGGLATTA
                     ELQGDKWVINGEKKWIGGAATADVLPIFARDVADGQIKCFMVPGGTPGLTVDKIDGKIS
                     LRLIQNGHIKMNNVQVDKTARLENINSFRDVAKILYTTRADVAHLATGLHAGALANTLK
                     YVKEREQFGKKISQFQLVQEKLARMQANCVTSLALSHRLAQLQEQGRYEEVQSSLAKMN
                     NAYRLRETVALGRELLGGNGIIVEHDVARFFVDAEAAYSYEGTHEVNSLILGRFLTGKG
                     AFV"
     CDS             17782..19023
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Thiolase_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Thiolase_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_105"
                     /sec_met_domain="Thiolase_N (E-value: 1.5e-80, bitscore:
                     264.3, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="Thiolase_C (E-value: 2e-42, bitscore:
                     137.8, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKNLDQIVIVGAARTPVGAFLGNLKTVKVQDLGVTALKGAVERA
                     GIKMEDIDEVIAGHVVGSPTSSNIGRVVGLDAGVPIEKTGYTVNRLCGSGIQSAVNAVQ
                     VLQTTDKKVIAAGGAESLSRAPYFLPEEVRYQGFRTGDQQLIDSNTMIHTGCVGKEFPE
                     IIHMGQTAEKLAQMYDISREEQDKFALNSQAKAKKAIESGRLAQEIVPVEVKDRKGNVT
                     VVDTDSHPKPDTTMEKLAKLRPAFVKDGSVTAGNASGLNDGAAFEIFTTADYAKDNGLE
                     VMAKVVDYAITGCSPDVMGLGPVESVREILKRNDMTLEDIAVLEINEAFAAQTIACTKE
                     LGNEPGTALYERLNPNGGAVALGHPLGCTGARIITSICYEFKNRPDIKYAIASACIGGG
                     MGIAMLFENGYYQG"
     CDS             19052..19903
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_106"
                     /sec_met_domain="HCDH (E-value: 1.3e-35, bitscore: 116.1,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH_N (E-value: 7.6e-68, bitscore: 222.0,
                     seeds: 60, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIKNTLVIGSGLMGSGIAQVLAEAGYQVYLKDIKQEFLDKAVEK
                     IRKNLDRKVSKGKMEAPEVDKVMSRLQTTLTYDEAKDCQLVIEAATENHDIKLKIFKEL
                     DEATPDETILATNTSSLSLTDIASVTKHPDQVVGMHFFNPVPVMKLVEVVRGLQTSDET
                     VAVAQQVIDQMNKTMIVAKDAPGFAVNRILVPMLNEAIFTYGEGLASREDIDTGMQLGA
                     NHPMGPLKLCDLIGLDTLLAVMNVLYDGFKDPKYRPAPLLVKMVEAGYYGMKSGKGFYD
                     YD"
     CDS             20254..21513
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CoA_transf_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_107"
                     /sec_met_domain="CoA_transf_3 (E-value: 1.8e-96, bitscore:
                     317.5, seeds: 55, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNERKALIKEYGPLAGMRVLGSGSIVAMPTALGLLGDLGAEVIN
                     IERPGYGDSMRMLSPTSSKTGVSNGWMQEARNRMSMALELNCNIPEVKELFFELIKEVD
                     VYMENMVWLDKLGIHDEELLGVNPKLVIVHISGFGRAEFGGEEGVIGRASFDMIGQAFS
                     GFMHLNGQPAPHEPQITGPYTNDYVSAYMAAFGALAGYISAQKTGKGQVVDVSQFEAMA
                     RMLCDNFVSYTENGKVTARSGNVNERFQPYGLFEDKNGEFVTIGAFGKNVYLRFMDAAG
                     LDAEKYTFENAGNGVEAVMSAHGRALDREIREWAASKTAKEIEEILNAKKVPASKVNTA
                     EDAYKSEHFQSRGDFIKYVDQTSGQEVEAFGIVPKFSATPGDVWRGAPTMGQDTETILK
                     ELLNYDDAKISSLREQGYIG"
     CDS             21581..22366
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ECH_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_108"
                     /sec_met_domain="ECH_1 (E-value: 8.9e-57, bitscore: 186.3,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKVIYEVKENIGQIILNDPKNLNAIDDSMAEDLLAALQQAEADP
                     EAKVITITAAGKVFCGGGNLKHILSQFEANPDYDLHDLAKKVADTSLFMKKCKKLIVIG
                     SQAAAAGAGFNLALAGDFLIASEECQFIQAFVKIGLVPDMGGSYLLSRAVGANKAAQLA
                     LTGNPVKAQEGLELGFIHQVVANNELEGAVFDLAKKLARGPLKAYELIKAELFEASFKD
                     FEAYLETESHLQSEASHTEDFKEGVRAFVEKRRANFVGK"
     CDS             complement(22527..23453)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ApbA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_109"
                     /sec_met_domain="ApbA (E-value: 5.9e-41, bitscore: 133.7,
                     seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLIYIAGSGAMGCRFGAQLHEAGQEVILLDNWDDHINTIKENGLK
                     ISGDDERIVPMTIMKPQEANRVGDLIILFTKAMQLPAMLESIQGIMDSHTKVLCLLNGL
                     GHEEVIKQYVPERSIIMGVTVWTAQLVGPGHVKLASTGSINIQSIDANEAEMGHKVAEI
                     LNEAKLNAIYDQDVIPSIWRKACVNGTMNSLCALLDCTIGQLFATEPGLQLVHEIIHEF
                     VQVGQAEGVKLDEEAVTDYVMKTSVTAAHHYPSMHQDLVQNHRYTEIDFINGAVARIGD
                     KHDIETPRCDVITQLIHTKEKILIEPK"
     CDS             23514..24404
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     -3.2; E-value: 30)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg4_110"
                     /sec_met_domain="LysR_substrate (E-value: 1.5e-19,
                     bitscore: 64.3, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1.9e-17, bitscore: 57.1,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNITQVKYFIEIAKCHSISEASRNLFVTQPTLSLALKKLETELNC
                     LLISRNESGLELTAAGKILYDEGQVLISHVDKITQQIHNLQNQKDKNPIRLGMTTLFAI
                     QFAKELALFTATHQNVALTIIQDGSRLLQQMLANQELDIGLLSYPNYEADKITIEALHT
                     STKGYQVYVVVPKSNPLAQHSRLSFDDLKDQVFSSLTEDYMLGIMLAERAEAHGFKPNI
                     LSYYTDLQAMLHSLNSSNTICLMAIEYKHLVPLDNLVWIPLDDKSNYFSIGIALNKSIK
                     PSQNILDFIDILKQN"
     CDS             complement(24401..25453)
                     /locus_tag="ctg4_111"
                     /transl_table=11
                     /translation="VKTMQEVTKVSPKDFLNKVLTGTAQGTIIALIANAVLSAILSYFS
                     SNHYILMVIQAAVILQLATPLIIGGLIAKQFNFDPMRIMVIAGAAFVGSGVIKYDPAIA
                     AYVGKGTGDVINIMLTSAIAVLATLWIKNKFGSSSIIFLPIVVGVGVGFIGMLTYPYVT
                     MITTAIGSLINNFTSLQPLFMSILIAMSFAALIISPITTVGIGLAIGLNGVSAGAAAMG
                     VAATTVCLVVNSWKVNKSGVTLAIALGGMKMMMPNLFRHPIILLPCLTTAIVSAIPVAL
                     FAVSGTPQSSGFGLVGLVGPLASLDAGLTFPLLILCWFVVPIATALICQFVFEKVFKLY
                     QRETVFHYYG"
     CDS             complement(25546..26865)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) oxoacid_dh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 71.9; E-value:
                     1e-22)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_112"
                     /sec_met_domain="Biotin_lipoyl (E-value: 4.4e-22, bitscore:
                     71.9, seeds: 40, tool: rule-based-clusters)"
                     /sec_met_domain="oxoacid_dh (E-value: 1.2e-75, bitscore:
                     248.0, seeds: 75, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLVKVKMPNLGESVTEATVVAWQVKVGDQVEKYDTLLEAQSDKV
                     TTEIPSDYQGTVKEILIQEDETVPIGTEILVIEVAGEGESGSDESSEPEVESKPTLETT
                     PSQAESRASAKPSNHSKGGRFSPAVLHIAQERGIDLSQIVGTGKGGRITRKDVINYEPT
                     SAENKPTQVKELKPELVQTSLDPQPQPELKSEQNNKPVTSSLDSQQEIIKADGVRKAIA
                     KKMVQSVTEIPHAWMQIEVDVSNIVALREKTKSQFMQTEGLKLSYFPFFVKAVAQALKK
                     HPMLNSSWQDNNIVLNKDINLSIAIAAGDNLFVPVIKHVDNLSISGIAKEVDRLALKAR
                     SGKLTSEDMVGGTMTVNNTGTFGSVASMGIINYPQAAIIQVESINKRFVPTADGGFKAA
                     DMINLCLSFDHRILDGLAAGNFMKDVKENLQRFNNENDLY"
     CDS             complement(26879..27865)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transketolase_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transket_pyr"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_113"
                     /sec_met_domain="Transketolase_C (E-value: 2.7e-40,
                     bitscore: 131.2, seeds: 80, tool: rule-based-clusters)"
                     /sec_met_domain="Transket_pyr (E-value: 2.2e-43, bitscore:
                     142.0, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAILTYLEAINKGIEEEMARDEKVVIFGEDVGGEKGGVFGVTKGL
                     AAKFGDQRCFNTPLTEGEIGGLAVGLGVMGYRAIGEFQFADYILPATNQIISEASRMRY
                     RTKGDWTAPIVYRTPYGGGVRGGLYHSQSTEKVFFGQPGLRIVTPSNPYDAKGLIKAAI
                     RSDDPVLFYEHKRLYRLLKAEVPESDYVVPLDKANVVRQGDDITVIAYGMALVHALNAA
                     EKLAEEGIQAHVVDVRSIYPLDKETLIEAAKKTGKVLLVSEDNKEGAIIGEIAAIIAEE
                     ALFDLDAPIKRLAGPDVPSMGYALNLEREFLINEEKVMAAMRELAEF"
     CDS             complement(27886..28869)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) E1_dh"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_114"
                     /sec_met_domain="E1_dh (E-value: 1.1e-86, bitscore: 284.6,
                     seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKLAKSGLSKEEIIEVYKHVLRGRRLDERLWQLTRIGKSSFNIS
                     GQGAELAQVAMAMAFDPKKDYFLPYYRDMTACLVWGMTSKDIVMGTFGKEADPSSHGRQ
                     MPNHYGSKEHNIVSHSSTVSTQIPLATGVGYAAQLEGKDYVALVTTGEGSANQGEVQEA
                     MNFAGVKKLPVIFVVENNGYAISVANREQYANDDFSYRGPAYGFPGVTIDGNDFTATYL
                     AFKEAVERARKGEGPTLIELVVSRLTSHSADDDQSIYRSKEEIDGLKDKDPLNVFEKQL
                     IAEKYLSREEMDQIDADLKAEINQATDEAEAEPDPSPESVYEQVWA"
ORIGIN
        1 atgttggctt tttcctcgat tacgaagtaa gcatttactt cttcggtaat gtcttctccc
       61 ggtttttgtt cgtctacata gtgggcaatt actggtactg ttagcttttc accaccgtca
      121 aaagcttgag ggtctactgg cttagctgat accttacctg ttttctcatc aacttttaca
      181 gtccacttat ttcccttatc atctgttgcg agtttattac ctgcttcatc actttcaagt
      241 gtatctggaa gagtaaattt atttggtgga attctctttc catcttcagt ccatgtagca
      301 ggtgatgttt gctcatttac tgggtagttt acttgggcgt cgtattctgg tctgatgtag
      361 gttgactctt ggactacaaa gtggaaccag tggacgtctt ttgacccgtt ggtataggta
      421 tattcaagcg ggatagctat gaagtctcct gccttagctg attttggtgg agtgattgta
      481 aaattagaaa tgtcgttagg atcaacatct accttccatt gatcttccgg tgcttttccc
      541 ttattttcac ggtcgataaa gtccatgata agcttaccag aagcttctcc cctatcttgg
      601 gcaccattca tttcctctgc tgacttgtca gtatcacttg ggttttctgg ttgtacaata
      661 cctaccttaa attcctcgcc tggttttaca gcagaggatg ttacctttga agtctcatcg
      721 ccattgccgt ctacgaatct ttgatcataa tatcttgtat cgtcaagatt tagcttaaaa
      781 tcaccgatta agttgtagtg atcgtagcgg tcgatgcctt gcttgtcgat tgtgacatta
      841 tctcccttgt gattgatgac agcagtacct gcccctgttt ctacataagt tcctgtgcta
      901 ccaagatcat cttctgtttc tgctattttt ttaaattctt tagctgttct tggacgggca
      961 aagaatttaa catctaggtt ttgtagcgcc ttgtagtctt ttgtattaaa gatggagtct
     1021 tcattgatta ctgttttgcc attttcatcc ttttttaggg caccttctgg catcttaatg
     1081 tggatatttc cattttcgcc aatataggca cttgctcccg gaacgatttt acctgtaata
     1141 ggattataaa cttggccgac tagtctttcc tttgcatttt catcgatatt gtctaccttg
     1201 ataccagtgt cgatatcttg accttggaca aagtattttt tgtttggatc gtagttgttt
     1261 ttattaagct ttaattcttc tagcttatca ttttcatttg gccatgggtt taccttgtaa
     1321 cctaaagcga agttatcacc aaaaaactta atatctggat tttcttgagt atagttatcc
     1381 ttcataccaa aggaagtaga attattatcc ttgttgttga tatgcttcag ggtctcttca
     1441 ctggcttcat agtttaagtt tctttgtcgt ctagaagcgg atatattcga atcttctccc
     1501 ggcttataag ttacctctgg agattcaggc gttaacttat ctccctgacc catcattggt
     1561 ttatcacctg gattcacaag tgtaagaccg gaatccgtaa cataaatcct agtataggtt
     1621 ctttgaccag tctctttgtc tatggtgacc tgataacccc attcagtctt gcttggcgaa
     1681 tctgctgatg ggttcttaag ttcaaattta aaaccgtctt ttactttctt ctcgtcatcc
     1741 ttaccgaacg attgatttgg atctcccggt tgtaggtctg tttctttata acgttcagat
     1801 ttactatagt cttttatttt cttttcatct tcaccatagt ttgggtcatt tacttgtgga
     1861 gcagctgctg gttccgcttg agaagccgct tctgccccat aagctaccgc ttgtacttca
     1921 ggacttgctg gtaattcctc ttctactggc gcttctggct ctactatttt atcagttact
     1981 tgtgtattat cactctcagc agcagccgca gtcggcgctt gcccagctat aaacgcagca
     2041 attgccacgc tcgctaatcc taagcttgtc ttacgtaaag tgtatctgta tcgtttgtcc
     2101 atatatccta ccttcttata tatttatttg gatgcattgt aatttataat atacaatcca
     2161 accatcgcaa actattccgc atattttatc cctatttttt atgtgattca cacttttccc
     2221 aatgatttcc tttccattgt gtctactgtg aatgacttat tatattataa tatttttaag
     2281 gctctatttc aatagacatt ggtaaatagt gattattgaa tttatagggt tgtcaaacat
     2341 atgttacaca tactgaaact tcggatgccc tagacctaac gactaactat tctttcatta
     2401 gaaaacaaaa aataagagag acaaggacat aatatatgta ctcatctctc tggtccaact
     2461 ttttggggtc actatctgac tgaaaagtcc aagcctaggg gctattttta tggagttatc
     2521 taagaattat tggaagaaat ttaagagtaa cccagcggct acggccgacc caatgacacc
     2581 agccacattt gggcccatcg catgcattaa taagaagtta gccggattga cactttggcc
     2641 caccttttgc gatactcggg cggccatggg aaccgcagat actccagcag acccgatcag
     2701 tggattaatt ttacccccac tcagacgata cataagcttg ccaaaaagga cgcctgaggc
     2761 tgtccccaca ctaaaggcca ctaagccaag aaccacgata ctcagggttt gagcggttaa
     2821 gaagacttcc cccttagccg ttgcaccaac cgtcaaccct aataagatgg taataatata
     2881 cataaaggtg tcagttaaga ccgaagtcaa tttaggcacc actcctgact ccttaattaa
     2941 attaccaagc atcagcatcc caatcaaagc ggctgctgag ggcaataaca agacggtaaa
     3001 aattattacc acaatcggaa aaattatttt ttcccgttta gaaaccggtc ttaactggtc
     3061 catttttacc tgacgttctg cttcagtcgt taaggctttc ataattggcg gttgaataat
     3121 tggaaccaag gccatataag aataagccgc aatcgctatc gcacccaaaa tatggggtgc
     3181 caattgcgaa gtcaaataca aggcagtggg accatccgca ccgccaataa ttgcgactga
     3241 ggcagcttct tgcggggtaa agtgaatgcc cggaataaag tcatttagca aaaaagctcc
     3301 aataaaggta aaaaagatac caaattgagc cgccgcccct aaaaagatac ttttaggatt
     3361 ggcaattaaa gggccaaagt ccgtcgaagc ccccacacat aagaaaatga gaggtggata
     3421 aatacctaat ttagttcctt ggtaaagata gtaaaataag ccaccctcct ccatcaagcc
     3481 cgtcacaggt aggttaacca aaagcatccc tgaagcgatt ggaatcaaga gatagggttc
     3541 ataaccttta gcaattgcta gatagagaaa ggtacatgca aggacaatca ttatcacagc
     3601 ttgcatcgtc agactagcaa gacccgttga ctgccagaaa ttaattaaaa cttccataaa
     3661 agtccctcct tgcacctagt taagctaagc taatgagcag gtcacccgta ttcacagcca
     3721 agccctgact cgtatgaatt tctaccacct tgcccgcttg gggtgcgact atctcatttt
     3781 ccattttcat ggcttctaaa accaacaaaa ctttccctgc ctctacctgg tcacccatct
     3841 taacctgaag actgaggact gtccctggca taggtgcact aatcacttcg ctaccacttg
     3901 cttccggatc tttaggtcgt tttgcaggtg aggctggttt aagtggttga gatggccgaa
     3961 gactacgcga aggttggggt ttagcttcct ggcttgcctc aatttccgca acttcttcaa
     4021 tttccacctc gtactcttga tgatcaattc ttaccttata cttttttatc atgtttaatc
     4081 ctccctactt gaaattggtc gtgtgttttc ctgcaaccct gccatggccc agatattata
     4141 gtcatgctga cttctacgaa ttttgtggac gcgaaacgga tggctatcct ggccgcgata
     4201 ggcctgaatg gcagccacaa tggcagcgac ttgcttcgtt tctaagtgat tggctgatac
     4261 tagatctgat tgggtctgat tctttgccgg tatacttggg tcagcttgag tgtttacttg
     4321 tttagtacct aaatacttaa aagcagaaag gatcagagca atcaccatca aagttaaaaa
     4381 taccatggcc atgctaaaaa tcgtaatata aatggattcg aataggctta ccccatcatt
     4441 gacattcata tgaatcctcc ttttataatg gcaagttacc atgtttctta gctggacgac
     4501 cttcccgttt acccgctaac atatcgaagg ctgaaattaa cctttgacga ctagtacttg
     4561 gttgaacgac atcatccaca taaccacgag ccgctgcggt ataaggatta gccaccgcct
     4621 gccggtagtc tctaatctta tctgcccgca tttggtcagg atccaaggct gcttcaatgt
     4681 catgtttaaa gataatatta gctgccccgt cgggccccat gaccgctatt tcagccgtcg
     4741 gccaagcata aactaaatct gctttgaggt gtttagagca catagcaatg taggccccgc
     4801 cataggcttt tcttaaaatc acggttattt taggtacagt agcttctgaa taagcatata
     4861 agagcttggc tccgtgacga ataataccgt tatattcttg gctggttcct ggtaggaagc
     4921 caggcacatc caccaaggtt aataatggaa tattaaaagc atcacaggtc cggataaaac
     4981 gcgccgcctt atcggaggcg ttaatatcta aacagccagc taaattattt ggttggttgg
     5041 caacaatccc cacagtttgc ccgcccatgc gaccaaagcc aatcacaata tttttggcaa
     5101 aaagggcttg tacttcaaag aaatccccct catccaaaag actttcaatc acttggtgga
     5161 tatcataagg cttattaggt gacgccggaa ttatttcatc taaacgtaga tctaagcgat
     5221 tcaaatcatc tgaaacggcc acccttggtg ctagctcaag gttattggca ggcagaaaac
     5281 taagtaattt acgaattcgg gccagagcgg cttcctcatc gacatcaaca aagtgagcca
     5341 caccagagct ttgattatgg gtggtcgccc cccctaaggc ttctgcggtc accacttcac
     5401 ccgtcactgt tttaaccact tgcggtcccg taataaacat attagagctt tggtccacca
     5461 tcaagataaa atcagtcaaa gcaggtgaat agactgctcc gccagcacaa ggccccatga
     5521 tgacagaaat ttgaggaatt tgacccgaag ccattacatt attaaagaag atatcaccaa
     5581 agcccgccaa agagtcgacg ccttcttgaa tccgtgcccc accagaatca ttaatgccaa
     5641 ttaaggggac gccaactttt tgggcgagtt cttggacttt aacaattttg gcggcatgca
     5701 tttgacctaa agacccaccc attacggtaa agtcttgggc aaagcaatag actaaccgtc
     5761 catcgattgt accgtaacca gtaaccaccc catcccccag cggacgatct tgatccaaac
     5821 caaactgttc acaccggtgt tgaacaaagg tgtctaactc aacaaagcta ttcgcatcaa
     5881 ataatttatc gagtcgttcg cgcgcagtat acttgccctt agcatgttgt tttccaatac
     5941 ctttgctccc acccgcttgc tgggctgcca ctttttttga gtctaattct tttaacttgt
     6001 cattggccac aatggctcct cctaactact ctcgtatcaa ctttaatttt cacatacgac
     6061 ctttttctaa tataaaaagg tccaataaac agtgtaaaat ttataacacc cgtttattgc
     6121 acctctgcaa ataaaccaaa aagtaagttt tcttgtctat gacacgacca gccaggtaag
     6181 aatctgagct tgataagaga aaacgttttc tttgagctta ttatattaaa ttttgaagga
     6241 gctatgcaac ttatttgact agataaataa gctaaaactc atttctttaa atgccttaat
     6301 tgatggttcc gacggcgttg gtcccggatt agtttcttaa ccggttcttc gccttcgatt
     6361 ttgattacgc gggtattagc catgtaatca tgaagggccc gacctgagcg tgtaaaaatc
     6421 actaaaatta aggaaaccat agctaaaatt agacccgcag ttcctaaata attttctgta
     6481 taaaaacccg tcataaggct taaagtctct tgtaaatatt ggcccatggt aaaagcggcc
     6541 ccttccacta caacaaagcc cacaaggtgg cgcatcaata aagcttgcca agaagttgtt
     6601 tcataatcct cagcttccac aatctttaac ttggtcattt tcttacccaa ggtctggcct
     6661 ggccatactt tatatggaat aaacacaaaa tataaagaat aaaatattaa agctaaaata
     6721 aaacttagat aagaccaagt ctctgctaat ccataggccg gaaatgaata taaattttta
     6781 taactcgctt ccttagctgt cattaaagaa aacatgacaa agggaccagc catcacaaag
     6841 agattcccga aaaaccaatc cgcaatataa gcagaaagtc gcggaattag atcaacctgg
     6901 gagggtcttt gatccaatcc tttgattgaa gctaaagttt tactaatgat attatcttgt
     6961 ttcatacgct actcctaact taaacaatca ttataaatcc aaagaaggga tggcattaat
     7021 ggaaagatcg gcaaagtcct tggctaaata cattggataa gccacggccc caatcatagc
     7081 ggcattatcc ccacataagg ataaaggtgg aatctgtaaa tcgatttgag aaaaattggt
     7141 ctgaatgagg tcagtaagag ctgcccgtaa acctgagttg gccgccaccc ccccggctaa
     7201 aataaactgc tgacaattag gatggtcttc taaagcagtc ttaactttac tggtaaggat
     7261 ctccactaca gccgcttgga aagacgccgc aaggtcagct tgattaatgg tttgtcctct
     7321 ttgatgggca ttatggacta ggttcatcac ggccgatttc atgcccgaaa aagagaaatc
     7381 taaattatct tcatggagca tagcccgtgg tacatcatac gattcttgac cttggtgagc
     7441 taattggtct aaatattttc cggcaggata aggtaaatct aaaatccgcc ccactttatc
     7501 ataggcttcg ccgacggcgt catcctgggt ttccccaatc acttgaaaat caaggtggtt
     7561 ttccaaataa actagttcgg tatggccgcc tgatacaatt aaagctaggg ccggaaattg
     7621 taaaggtgct tgtaattggc tggcatagat atgcccagct aagtggttga ccgcgatcag
     7681 cggtttatta tggattaagg ccaaagtttt agctgcggtc acgcctacta aaagagcccc
     7741 cactaagcct gggccttggg tcactgcgac cgcatcaatc tgcttccaat ttactttgcc
     7801 ttcctttaaa gccaaattaa caagttgtga aatctgctcc acatgatgac gactagctac
     7861 ttcaggtacg acgccaccaa accgcatatg acttttaatc tgtgaggcaa ccaaatttgt
     7921 taggattttg tggccatctt caatcaaagc cacactggtt tcatcacagg atgattcaat
     7981 tgctaaaatc acagtcattc tattattcct ttcatttcca tcttgcatcg attcattaaa
     8041 atattccctc gcttatacac cattgcataa tgatggcatc ctccctaggg tcatgataat
     8101 aagctggacg ttgatcaatt actttaaaat tgtatttggt ataaagagca cgtgctgctt
     8161 ggtttccttg ccggacttct aacgtcaccc tgcttgttga agggaggctg gctaaccaat
     8221 cttgcaacaa acgacttcct attccttggc cccggcactc tggcgccacc cagacttgat
     8281 taatggtgat atcttcaaaa agatgatgat aagcaatata agcgatgaat tcactgactc
     8341 ctgcctgact aactaaacag gcataataac tgtaggataa tgtaaaatca gcctgactgg
     8401 ccttaagggt ccaacccaaa ctttgattct gctcagccac aaaggtttgt tggtccgcag
     8461 ttaagtcttg acttgctaat atctcaaacc acattgagct tgcccccttt attctggcaa
     8521 aagtctgacc atagcatagc catcttcaaa attatcaaag taatagtgtt ttttgagatg
     8581 gtcaatttta aaacctagtt tctgatacaa attaagggca atctgatttg aaactcggac
     8641 ttctaactct gttttactaa tttgtaagta atcagcataa gccaaaaact cttgcaccat
     8701 aaacaagccc agcccgtagc cacggaagtt aggtaccacc atcacatgac taatatgggc
     8761 tgacctcgct tgtaaacgtc ccgaaatgcc tgctaccatt tggtcgtctt gatccactaa
     8821 aaccaggtaa aggcagtaag gattgcgggc aaaatcagtc tggaaatctg cttctttcca
     8881 agccaaataa ccattataag cagaagcttc tagttcggta taggctgcaa tatcatgtgc
     8941 tgcaatgggt tgccattgta aatcaaaagc ctgccaggct ggattctgcg aaattgtcac
     9001 ttgaccctgc ttaattaagg gagctaaggt gtgcaaaagt tgatggttac gcggttgccc
     9061 tttaggctga ctgggtttaa ttagttgttt tatagtggtc aataaatgct tcattttcag
     9121 ctcggcttgc taccctcctt tgatggtctt gggcccaatt ttgttctgcc agagtggcat
     9181 gggcataatt tggggccaaa gtatgcggat cagtacaccg gtttaattga cctaccatac
     9241 ttaggttaaa gacgcgttcg acatgtggaa gtgcctcctc cgttgtcaca gtatcaagct
     9301 ctattttaga atagatttct tgaaatactt ggataaaaga ctcagtatca tgacctacta
     9361 ttaatacttg gctagtatca tttaaaattt ggctgactgt ctcactttgc aaccattctt
     9421 taaagtcacc atggcagtct gcttgtaagt tttccaaccg attattaata ggattatggc
     9481 tatataggcc gatataagcc gataaacggc gggcatccat tagggagata attactgggg
     9541 ctattggggc tgaggaaatt tggagtgcca gagaggacac ttcatataat ggcactgcca
     9601 agcttgttgc ccaaacttta gcaaaggtaa ccccaatcct aagtccagta taagagcctg
     9661 ggccgatacc aacgacaaca gcttcaatat cagcaactgt ccaggaaact tctgccaaaa
     9721 gtgcctgaac actggccact aaactttgac catgttgttt attctccttg ttaaattggc
     9781 tagcaatcac tttactatca gaaaagttgt ttgttaactc tccttgaccc aataccaaag
     9841 ataaggcatc cgttgaagaa tctaccccta accaccgtgt cataaaaccc cttcctttcg
     9901 tgcactcatc ttatcatatt ttggcataaa gaaaaataca ggttacttaa aatgaaagta
     9961 acctgtattt ttagtgtttc actgtgtttg actcacattg ttattgattt ttaaattcag
    10021 cttctcgctt ctctacgaag gcacccattc cttcactctg atcttcagtg gcaaagagca
    10081 agccaaacaa ttcagattcg taatcaagcc ctttgtctaa ggacatatca attccttttg
    10141 aagcagctaa tttagcgtat cttactgcaa ttggtgcttt tttaatgact ttttcagcat
    10201 aagcataggc ttctggcagt aattgttcca ctggatataa gcggttaaat aagccagctt
    10261 ctaaggcgac atctgcttta agatttccac ccgtaaataa gaattcattg gctttagcta
    10321 gcccaataat ccgagggaga cgttgggtac caccaaagcc tggaataacc cctagtccga
    10381 cttcaggtaa gcctacgacc gcattctcac aagcaaaccg taaatcacaa gccatggata
    10441 gttctaaacc tccccctaag gcatagccat tgatggctgc taaggttggc agggataagt
    10501 tttggatggc tttaaagact tggcttccta agcgagagaa gtctcgtgcc tctaatgggt
    10561 ttaggttagc catttctttg atatcagccc cggctacaaa ggctttatca cctgcacctg
    10621 taatgatcaa aaaatgaatc tcaaattgac cgccttcgat agctttgaca agatcataaa
    10681 tttcatttaa ggtttctgaa tttaaagcat ttaaggcttt agggcgattt atcgttaagg
    10741 ttccaatctg atttttaaca tcaaataaaa tatttttgta ttcagtcata tcaagctccc
    10801 ccttaatcgt atttgtagaa tccttgacct gatttcttac ctaaacgacc agctgccaca
    10861 tattttttca ataatggaca tggacgatat ttaggatcgt taaagccttc gtataaaacg
    10921 ttcataattg ataagcaagt gtctaaacca attaaatcag ctaattttag cggtcccatt
    10981 ggatggttca tacctaattc catgacttga tcaatcgctt ctggcgtagc aactgattca
    11041 taaagggtga aagctgcttc attaatcatt ggcattaaga cccggtttga aacaaaacca
    11101 tatgagtcgt tcacttcaac tggatcttta gtcatttcac gtgaaagatc ttcaatgact
    11161 tggtaaactt catcactggt ttcaacccca cgaataattt caactaattt catcacaggc
    11221 actggattca taaagtgcat cccaatgaaa cgttgtggct tagaaacaac cgcagctaag
    11281 tctgtaattg gtaatgaaga cgtattggtc gctaagataa catcttcgcc tacaattcca
    11341 tttaattctt tgaagataga ttttttgatt tcaaaatttt caaccgcagc ttcaataatt
    11401 aattggcaat ctttagcatc ttgtttatca gttgaaagtg taatccgatc taagatagtt
    11461 tgtttttctt cttcagactt acgccccttg tccacatcac ggcttaaatt tttaatgata
    11521 tttgctaaac ctttttcagc aaattcttct ttcatatcat ttaaaataac ctcataacca
    11581 gcttgagctg acacttgcgc aattccatta cccatttgac ctgaaccgat gaccataatt
    11641 tttttgattt ccattatatt taccaccttt tcttattatt tttactaatt tataaactaa
    11701 attaatcgta atcacattgg attaagatag catctccttg ggctgcccca gaacaaatgg
    11761 ctgccacccc atattttgct ttacgacgcc gcatttcgtg aacaagtgtc gcaataatcc
    11821 gccccccaga agctccaata ggatgaccga aggcaatcgc ccccccattc acattaatct
    11881 tttcagatgg aatgttattc attttttgtg atactaaagt gactgccgca aaggcttcat
    11941 taatttcgaa aagatctata tcatcgaccc ttaagttatt tctatcgagt agatttttaa
    12001 tggcatgacc tggtgctgaa gcaattaatc gcgtttctac cccaacttct tcgtggtcta
    12061 gaattgttgc cagtggttta aggcccattt ctttagcctt gtcttcagag gcaataacta
    12121 aagctgaggc cccatcattc gttgctgggg cattacctgc cgtcactgta tttccatcga
    12181 caaataaacc aggcatacga cttaattttt ctaaattagt gtctggtctt ggggtctcat
    12241 cttttgaaac ggtgattggg tcttttttcc cttgaggaat ggtcagtgga atgatttcct
    12301 catctaatcg tccggcttct tgagcttgaa cggcccgcat ttgactttga taagcccact
    12361 catcttgggc ttgacgacta atgtcatatt catctgcacc atagccacca ttgaccgcca
    12421 tatgttgatt ataaaaggca tcccaaaggc catcgtaaac catcaaatca ataaactcag
    12481 aattaaacat ccgatgaccc cagcgcatat ctttagaggc aaatggggtg ttagacatcg
    12541 attccatacc acccgcaacg attaggtctt tgtccccaca acgaatcatt tgatcagcta
    12601 gggtaactgc cctaaaactg gaagcacaca ccttattaat cgtttctgat ccgactgacc
    12661 agtctaagcc tgctttaatt gaagcttgac gcgatggaat ttgacccact cccgcttgga
    12721 gcacttgacc aaatacaaca tattcaatat tttccttatc gacgccggct ttttctaccg
    12781 ctgctttaat gacctctgct cctaaatcca cggccttaat atcttttaac atacctccaa
    12841 agcgaccaaa gggagtacga acccctgaca gtatcacgct gtgtgtcata aaaaatcatc
    12901 tcctttattc taatcatggc ttgtttatag taaaaaaaaa ttgtattctg aaagtaaata
    12961 tacttctatt ttatgatgga aaggataagc aaaatggatt ggaaaagtat aaattttcaa
    13021 catttaaatt attttctcat agcggcaaaa tatcaaaact atagccaagc tgctgatgaa
    13081 ctcttcatca attattcaac cctaagtaag gccattgcag gaattgaaaa ccaactgggg
    13141 gtgaaacttt ttgagaaaga cggccgtaac attaaactga ctaaatacgg caaaattctt
    13201 aatgcctctg tctatgctgc tatgaccaat attgaggatg ggcttgatga aattgctcgt
    13261 ttttcccatc ctgatcatgg ccaagtaaat atctcctcaa tttataccgt ctccgccaaa
    13321 tacctccccc gcctattatc ccgcttccgc aacctatttc ctgaactaag cctcgatatt
    13381 acccaagctt cgacccaaca aattattgat catgttttgg acggcacaag agatattggt
    13441 ttttgtggcg aatttgatta ttcctcttat tcttcagaac taaatcgcga atttatctat
    13501 aatgatgaaa tagtcctaat tgtcccagct aaccatcgtt ttgctgcgcg aaaatcagtt
    13561 tcttttgccg aaattaaaaa cgaacaattt atcggctgga atgcatcagc tggaatgtat
    13621 tatgcaatcc aacaagctat taatcgggta gctggtccta atttcaaact caacaccatt
    13681 tattctatga atgaagacac aggtgtcgta ggtatggtcc gggctggctt agggattgcc
    13741 tttagttcta aaaataccga attgaattat gatgacattc ggattttaga gttaacagat
    13801 ttatatatta tctataatgt ctacatgatt tgggcaaatt ctgaatttac cccaagcagt
    13861 ctgaagtcct ttaaagactt cattattgcc caaattaact agcttatttc tggtcataac
    13921 ttaacggata agcgcttaca aagtgactat agcacttttc ttcccctacg aatatagaat
    13981 tattttcaag gatttattca tttaattcat aggttttgtg aaatgatttt tatttttcat
    14041 ttaactctat actataagtt tcgcttatac tatattaaaa ctagctaaac tttaactttt
    14101 cttgattgag tataagtata acttatggaa gaaaacaggg tgaaaatttg cttttaaatt
    14161 cacatttctt gcttaaaaca ttgactataa ttaaaaatct ctctgaattt tttcttacga
    14221 agatgactcg atcatctact tttaaccaga ctatttaagg ctaacgcgaa atatttagaa
    14281 tttacctatt tgttttaatt aaagaataat gataagatta atcaataatg aaaacgtttt
    14341 atcattaaaa tataagaagg aggctgagta tggagataaa acaaattaat tattttctag
    14401 aaattgttgc ttcagatttc aacatttcta gtgcatctaa gaaactcttc atctctcaat
    14461 ctacccttag ccaatcgatg attcaatttg aaaatgatta tcaagcccag ctatttaaac
    14521 gggaaaaagg aagattaatt ggcttgactg accttggcca agcaatgtat aaatacgccc
    14581 aggaaatcca gaaacttcac caagaaatga tgcaagtcat tgatcaggat aaaaaagaaa
    14641 ccacccaaat tgttcgcatt ggtattccgc ctattctggt gagaacacgg tttcctcggt
    14701 ttctcctaaa tatgaaacaa ttgtatccag atttacgcat tgaatatatt gaagaaggtt
    14761 gccaaagact gtgtcaatta ctagaaaata aggaaatcga tattgcattt ttaactgatc
    14821 ccctgcctac tactaagcta ctcaattcaa aaactgcaat taaggatgaa tttgtcttat
    14881 ttatggataa aaatcatccc ctcactaaac aaaatcaagt gaaatggtct agcctcaatc
    14941 aatacagctc ggcaatcttt actgacgctt attcaaccca ccattttttt atgatacaat
    15001 gtcaaaaaga acggattgca cctaaaatat tcttagaatc aaattcttgg gaatacctga
    15061 ttgatactat taaaaatagt caactcatca cttttttgcc aaaatcagtc tatcccatgg
    15121 tcaatcggcg ccaaattact tatcgcccct ttgaaaggtc agcaaacttt aaaatattta
    15181 tttcaacaac tgatgagatt tatcaatcag ccatcaaaaa atgtgtttac gatgcactga
    15241 ttgattactg tagccaggtg gaggctgtag ccaacctatc tttagcataa tatgatcaat
    15301 ctatctaggg agtgggcttt ttagcccgca cccttttttt atttaaatag ataaataatt
    15361 aattggtata gctgataagt ttggttactt ttcaaaattt agaccattcc ttctgctaaa
    15421 aatctcctaa atcaataagt aaaacttaat ggtaaataaa tacagctaat tatcattgcc
    15481 cgatttgtga tttgttagca agattagtca tattattcac aaatgaataa ctcttgtaaa
    15541 agttggtatt acaacgttct ataatttaaa cgctttttat ttgtgataaa ttttaattat
    15601 agatgtatta gtattgataa tatcgatacc ctctatcaat acaaccaatt tgtaatacaa
    15661 gggggagctt gctatgctat gaaatgtaag cgcttatcat tttataaagg aggaattacc
    15721 ttgaaagaat tagcaacttt aaccctaaat attgaggata cactagcttt tttaaatcta
    15781 aatgctgtta aatctttaaa tgcaattaat tcagcgatgt tagatgattt aaacgaagca
    15841 atggacctac ttgaggctga tcctaatgtt aaagttctcg taattacagg aaatggcaaa
    15901 gcctttatgg caggtggtga tattaaggaa atgatggact taagccctga agaagcagat
    15961 catttcattg catatggtaa tcaaactatg aaccggatca tgaatttgag ccttgtaacg
    16021 atcgcagctg ttaatggttt tgctctgggt ggtggtttgg agttagccct aacctgtgat
    16081 attcgaatcg gaacgactgc caataaaatt ggtttcccag aggtcggctt aggtatcatt
    16141 cctggttacg gcggaactca acgtgcttcc cgtttaattg gtatcggtca gaccaaacgt
    16201 ttagccctta gcggagaaat tattgatggg gctgaagctc accggattgg cctacttgaa
    16261 aagattgttg agccagatca attaattgaa gaagcaacca aattcgctaa acaaattgct
    16321 aagaacgctc ctattgcaat taaacaagct aagttatcaa ttaattttgg ttctcaatct
    16381 acattagaaa atggcttaaa acttgaaggc gaaatcgtta aaggcttatt cagaactgaa
    16441 gataaatatg aaggtatgaa tgccttcgtt gaaaaacgta aagcagaatt caaaggtaaa
    16501 taaaaactaa gagaaagaga agtgaagtcc atgtcaaaaa gcaaaattga gaaattacag
    16561 tatttatacc ctgaagatat ttatggttac tcccatgatt taagtgaaaa tgaagttgat
    16621 tttcttctaa aactaagaga aaccttagaa aaagaactct atccagttat tgatgaccat
    16681 tggaaaaaag aattattccc aatggaagct ttcaaaaaaa ttactgattt aggtattatg
    16741 acggatcctt ccctttttga aggtcgcgaa aataaattaa agacctcaga aatctttaac
    16801 cttttccgtc tatatgaatt aaaccggatg gattcttcga ttggtgcctt cacaattgtt
    16861 catggtggtt tagcttattc aaccgtttta atcggtggta gccaagaaca aatcgattat
    16921 tatgctccta agttagcttc ttatgagtgg cattcttgct tcggcttaac cgaaccactt
    16981 catgggtcag atattgcggg tggccttgct accacagctg aacttcaagg tgataaatgg
    17041 gtcatcaatg gagagaaaaa atggattggc ggtgctgcaa ctgctgatgt attaccaatt
    17101 tttgcccgtg atgtggctga tggacaaatt aaatgtttca tggttcccgg tggaactcca
    17161 ggcttaaccg tagataaaat cgatggtaag atttccttac ggttaattca aaatggccac
    17221 atcaaaatga acaatgttca agttgataag accgctcgct tagaaaacat caatagcttc
    17281 cgtgatgttg ctaaaatttt atacacgacc cgtgcggatg tagcacattt agcaactggt
    17341 cttcatgccg gagccttagc caataccttg aaatatgtca aagaacggga acaatttggc
    17401 aagaaaattt ctcaattcca actggttcaa gaaaaacttg cccgcatgca agctaactgt
    17461 gtgacttcgc ttgccctttc tcaccgtcta gcccaacttc aagaacaagg acgttatgaa
    17521 gaagtccaat cttcactggc taaaatgaat aatgcctacc gtctacgtga aactgtggcc
    17581 ctaggtcgtg aattacttgg cggaaacgga attatcgttg aacatgatgt ggctcgtttc
    17641 tttgttgatg cagaagcagc ttactcttat gaaggtaccc atgaagtgaa ctcactaatt
    17701 ttaggtcgtt tcttaactgg taaaggtgcc tttgtctaat aaacttcagt atcctgtatt
    17761 ttaacaacga aaggaaaaag tatgaaaaaa aatttagatc aaatcgtaat tgttggggct
    17821 gcacggacac ctgtgggcgc cttcttagga aaccttaaaa ccgttaaggt tcaagatttg
    17881 ggcgtcactg cgcttaaagg tgcggttgaa cgcgctggta tcaaaatgga agatattgat
    17941 gaagtcattg cggggcacgt agtaggatca ccaacttcaa gtaatatcgg tcgtgtggtt
    18001 ggtttggatg cgggtgttcc tattgaaaaa actggctaca ccgtgaaccg tttatgtggt
    18061 tcaggtattc aatccgctgt aaatgcagtt caagtcttac aaacaactga caaaaaagtc
    18121 attgcagcag gtggtgctga atctttatct agagctcctt atttcctacc agaagaagtt
    18181 cgttatcaag gtttcagaac tggtgatcaa caattaatcg actcaaacac catgattcat
    18241 actggttgtg tggggaaaga attcccagaa attattcata tgggccaaac tgctgaaaaa
    18301 ttagctcaaa tgtacgatat ttcgcgtgaa gaacaagata aatttgcttt aaacagtcaa
    18361 gctaaagcta aaaaagcaat tgaatccggt cgcttagccc aagaaatcgt accagttgaa
    18421 gttaaagacc gtaaaggcaa tgtcactgtg gttgatactg actcacatcc aaaaccagat
    18481 acaactatgg aaaaattagc caagcttaga cctgcctttg ttaaagatgg tagtgtgacc
    18541 gctgggaatg cctctggttt aaatgatggc gcagcctttg aaatctttac taccgctgac
    18601 tatgctaaag acaatggttt agaagtgatg gcgaaagtgg ttgattatgc gattacgggt
    18661 tgtagcccag acgttatggg cttgggtcca gttgaatctg ttcgcgaaat ccttaagcgt
    18721 aatgatatga ctttagaaga tattgctgtc ttggaaatca acgaagcctt cgctgctcaa
    18781 acgattgctt gtaccaaaga attaggtaat gaaccaggta ctgctttata tgaacgtttg
    18841 aatccaaatg gtggtgcggt agccttaggt cacccgcttg gctgtaccgg agctcgaatc
    18901 atcacttcaa tctgttacga attcaaaaac cgtccagaca tcaagtatgc gattgcatcc
    18961 gcttgtatcg gtggcggaat gggtatcgct atgttatttg aaaatggcta ttatcaaggt
    19021 taattagaaa tcaaaaatag gaggaaataa tatggaaatc aaaaatactt tagttatcgg
    19081 ttctggttta atgggatcag gtatcgccca agttttagca gaagcaggtt atcaagttta
    19141 tctaaaagat attaaacaag aattcttaga taaggctgtt gaaaaaatcc gtaaaaatct
    19201 tgatcgtaaa gtaagtaaag gtaaaatgga agcgccagaa gtagataaag taatgtcccg
    19261 gttgcaaact actttaactt atgatgaagc aaaagactgc caactagtca ttgaagcagc
    19321 aactgaaaat catgatatta aacttaaaat cttcaaagaa ttagatgaag caactccaga
    19381 tgaaacaatt ttagcaacta atacctcttc tttatcctta acagatatcg catcagttac
    19441 taaacaccct gaccaagtag ttgggatgca cttctttaac ccagtaccag tgatgaaatt
    19501 agtagaagta gttagaggtt tacaaaccag cgatgaaacc gtcgctgttg ctcaacaagt
    19561 catcgatcaa atgaacaaga ccatgatcgt tgctaaagat gcgccaggct tcgcagttaa
    19621 ccggatttta gttccaatgt taaatgaagc aatcttcact tacggtgaag gcttagccag
    19681 tcgtgaagac attgatacag gtatgcaatt aggtgctaac catccaatgg gaccacttaa
    19741 actatgtgat ttaatcggat tggatactct acttgccgtt atgaatgtac tctatgatgg
    19801 cttcaaagat cctaaatatc gtcctgcccc actattagtt aagatggttg aagctggtta
    19861 ctatggtatg aagtcaggta aaggcttcta cgattacgac tagaaactaa ccattaatta
    19921 cttcttgtcg tactaactga cccagaacta gagtaaatta ggtcttcaat tatttattcg
    19981 aaggactccc tataaaaatt acagccaaaa tatttcaaaa aattctttcg attacctagt
    20041 tgataaacct aatttgctct agttttgggt ctaattactt tattcacaat atagactgaa
    20101 ataaaaatca aataaatata agtctcttat taccgcgact aaaaagtgca taaaatttga
    20161 aataattaca aagaactata gcttttttct tttggaaacg gtatcatata atagtgataa
    20221 tatacacaaa attatttttt gaggaggatt attatgacaa atgaaagaaa agctttaatt
    20281 aaggaatatg gtcctttagc aggtatgcgt gttttaggat ctgggtccat tgttgcaatg
    20341 ccaactgctt taggtctttt gggtgacctt ggggcagaag tcattaatat tgagcgtcca
    20401 ggttatggtg actctatgcg gatgctctcg cctacatcca gcaaaaccgg agtatctaac
    20461 ggatggatgc aagaagcacg taaccggatg agtatggcct tagaactaaa ctgtaatatt
    20521 cctgaagtaa aagaactttt ctttgagctc attaaagaag tcgatgtata catggaaaac
    20581 atggtttggt tagacaaatt aggcatccat gatgaagaat tattaggagt aaatcctaaa
    20641 ttagtgattg tccatatttc tggttttggt cgagcagaat ttggtggtga agaaggtgta
    20701 attggccgtg cttccttcga tatgattggc caagctttct caggctttat gcacttaaat
    20761 ggtcaaccgg caccacatga acctcaaatt actggtcctt ataccaatga ctatgtttct
    20821 gcctatatgg ctgctttcgg tgccttagct ggttatattt ccgctcaaaa aactggcaaa
    20881 ggtcaagtgg ttgatgtatc tcaatttgaa gcaatggctc ggatgctatg tgataacttc
    20941 gtaagttata ctgaaaatgg taaggttacg gctcgttctg gtaatgttaa cgaacgcttc
    21001 caaccttatg gtttatttga agataaaaat ggtgaattcg ttacaatcgg agcttttggt
    21061 aagaatgttt acctacgttt catggatgct gctggattgg atgctgaaaa atataccttc
    21121 gaaaatgcgg gtaacggggt tgaagcagtt atgtctgccc atggtcgtgc tttagaccgt
    21181 gaaatccgtg aatgggccgc ttctaaaacc gctaaggaaa tcgaagaaat cctgaatgct
    21241 aagaaagtac ccgcttcaaa agtaaatacc gccgaagatg catacaagag tgaacacttc
    21301 caaagtcggg gtgacttcat taaatacgtg gatcaaacat ctggccaaga agttgaagcc
    21361 tttggtattg ttcctaaatt ctcagcaact cctggtgatg tttggcgtgg agctccaacc
    21421 atgggtcaag atactgaaac tatcttaaaa gagttgctta actatgacga tgctaaaatc
    21481 tctagcctcc gtgaacaagg ttatattggt taatttaatt tttaagttct gacttactct
    21541 atggttcagt ttataaaatt tcaaacgaaa gagtgattat atgagtaaag taatctatga
    21601 agtaaaagaa aatattggac aaattatcct taatgaccct aagaacttaa atgctattga
    21661 tgatagtatg gcagaagact tattagcagc cttacaacaa gctgaagcag atccagaagc
    21721 taaagttatt acgattactg cagcgggtaa agtcttttgc ggtgggggta acctcaaaca
    21781 tatcttaagt caatttgaag ctaaccctga ctatgaccta catgaccttg ctaaaaaagt
    21841 tgctgatacc tccttattta tgaaaaaatg taaaaaactc attgtaattg gatctcaagc
    21901 ggcagctgcc ggagcaggct ttaacctagc cttagccgga gacttcctta ttgctagtga
    21961 agaatgtcaa ttcatccaag cctttgttaa aattggttta gtgcccgata tgggtggttc
    22021 ttacctactt tctagagctg ttggcgctaa taaagccgct caattagccc tcaccggtaa
    22081 tcctgttaaa gcacaagaag gactagaact tggctttatc catcaagttg ttgctaacaa
    22141 tgaacttgaa ggagccgtct tcgacttagc taagaaatta gctcgtggtc cactaaaagc
    22201 ttatgaatta atcaaagctg aactgtttga agcttcattt aaagactttg aagcttatct
    22261 tgaaactgaa tctcaccttc aatctgaagc ttcacataca gaagacttta aagaaggggt
    22321 tcgggctttc gttgaaaaaa gacgggctaa ctttgttggt aaataagaca tgatttttta
    22381 gattttagtt taaaatacta aaaatcctat ttgtaaccta atggaaattt ctcacccatt
    22441 agattagcaa ataggatttt ttattgattc attaaataag tcatctattc tataaaaatt
    22501 ttatctaaac tcgttataat ttagaactac ttcggttcaa tcaatatttt ttccttggta
    22561 tgaatcaatt gagtaatcac gtcgcagcgt ggcgtttcaa tgtcatgttt atccccgata
    22621 cgggcaactg ccccattgat aaaatcaatt tcagtataac gatggttttg cactaaatct
    22681 tgatgcatag atgggtagtg gtgggcggct gtcacagaag ttttcatcac atagtctgtc
    22741 accgcttctt catctaattt aaccccttct gcttggccca cttggacaaa ttcgtggata
    22801 atttcatgca ccaattgtaa gccaggttct gtggcaaata attgaccaat cgtacaatct
    22861 aagagggcac acaatgaatt catagtccca ttcacgcagg ccttacgcca gatagacgga
    22921 atcacatctt ggtcatagat tgcattaagc ttggcttcat ttaaaatttc cgctacctta
    22981 tgacccattt cagcttcatt ggcatcaata ctctggatat taatcgaccc tgttgaggct
    23041 aatttcacgt gaccgggtcc tactagttga gcagtccaca cggttacccc catgataata
    23101 cttctttctg gaacatattg tttgataact tcttcatggc ctaggccatt taataagcaa
    23161 aggactttag tatgactatc cataatccct tgaattgatt ctagcatagc tggtaactgc
    23221 attgctttgg taaatagaat aattaagtca cctacgcggt tggcttcctg aggcttcata
    23281 atcgtcattg ggacgattct ttcatcgtcc cctgagattt ttagtccatt ctctttaatg
    23341 gtattaatgt gatcatccca attgtctaat aaaataactt cttgacctgc ttcatggagt
    23401 tgggctccaa accgacatcc catggcacct gaacctgcaa tataaattaa catttgaata
    23461 cttcctctct ataaattatg gtacactaaa tttaaataaa ggatggtgac ctgatgaata
    23521 ttacccaagt aaaatacttt atcgaaatcg ctaaatgtca ttctatctca gaagcatcca
    23581 gaaatctttt tgtcactcaa cctacactct ctcttgcctt aaagaaactc gaaacagaat
    23641 tgaattgcct acttattagc agaaatgaaa gcggtttaga actgactgcc gctggcaaaa
    23701 ttctttatga tgaaggtcaa gtcttgatta gccatgttga taaaattact caacaaattc
    23761 ataatttaca aaatcaaaaa gataaaaatc ccattagact aggcatgacc accctctttg
    23821 ccattcaatt tgctaaagag ttagctttgt ttactgccac ccatcaaaat gttgcgctca
    23881 ccatcatcca ggatgggtca cgccttttac aacaaatgtt agctaatcaa gaacttgata
    23941 ttggcttgct ttcttatcct aattatgaag cggataaaat caccattgag gcactacaca
    24001 ctagcaccaa aggctatcag gtatatgtag ttgtcccaaa atccaacccg ctcgctcaac
    24061 attcacgctt aagctttgat gatctgaaag atcaagtttt ctcctcctta acggaagatt
    24121 atatgttagg aattatgtta gctgaacgag ctgaggccca tggttttaaa ccgaatatcc
    24181 tctcatatta tactgactta caggccatgc tccatagtct taactcctca aacacaattt
    24241 gtttaatggc tatcgaatat aaacatttgg tgccactaga caatttagtc tggattcctt
    24301 tagatgacaa atcaaattac ttctccattg gaattgccct taataagagc attaaacctt
    24361 cacaaaatat cctagacttt atcgatatct taaagcagaa ttaaccgtaa taatggaaaa
    24421 cagtttctct ttggtataat ttaaatactt tttcaaagac aaattgacaa ataagcgcgg
    24481 tcgcaatcgg caccacaaac caacatagaa ttaataaggg gaaagttaaa ccagcatcta
    24541 gggaagccaa aggacccacg agaccaacca aaccaaaacc agatgattgc ggcgtacccg
    24601 atacagcaaa gagggccact gggatggcgg aaacaatagc tgtggttagg caaggcaata
    24661 aaataattgg atggcggaag agatttggca tcatcatctt catgcctcca agtgcaattg
    24721 ccagcgtcac accactctta ttcaccttcc aagaatttac aactaaacaa accgtggtcg
    24781 cagccactcc catggctgca gcccctgctg agacaccatt caaaccaatt gctagtccaa
    24841 tccctactgt agtaatcggt gaaataatta aggcagcaaa agacatggca atcaaaatac
    24901 tcatgaatag tggttgtaag gaagtaaagt tattaatcaa ggacccaatc gcagtcgtaa
    24961 tcatagttac gtaaggataa gtcaacatcc caataaaacc aactcctacc cctactacta
    25021 ttggaaggaa aataatagat gaagaaccaa atttattttt tatccaaagg gtagccaaaa
    25081 cagcaatcgc agatgttaac ataatattga taacatctcc ggtcccttta ccaacgtaag
    25141 cggctatagc cggatcatat ttaatcacac cagatcctac aaacgctgca ccggcgatta
    25201 ccataatccg catgggatca aagttaaatt gtttagctat taaaccccca ataattagag
    25261 gggtggctag ttgtaagata actgccgctt gaatcaccat caagatataa tgattacttg
    25321 agaaataaga taaaatagct gagagaaccg cattagcaat caaggcaata attgttcctt
    25381 gagctgttcc cgttaacact ttattcagaa aatctttagg acttactttt gttacttctt
    25441 gcatggtttt caccacttcc tatatagtta aatcacttaa aataaaggat agcaaactta
    25501 gatatgacga gtctgctatc ctctttgcat actatcagtc attaattagt aaaggtcatt
    25561 ttcattgtta aaacgttgta gattttcttt tacatctttc ataaagttac ccgcagctaa
    25621 gccatctaaa atacgatggt caaaggatag acatagattg atcatgtcag ctgctttaaa
    25681 accgccatct gccgtcggaa caaaccgttt attgatggat tcaacctgaa taatcgctgc
    25741 ttgcggataa ttgatgattc ccattgaggc tactgagcca aaagttccgg tattatttac
    25801 cgtcatggtt ccacctacca tatcttcgct ggttaattta ccagaacgag ccttcagagc
    25861 caatcgatca acttccttag cgataccact aatagataag ttgtccacat gtttaatcac
    25921 aggtacaaat aaattatccc cagccgcaat ggcaatagat agattgatat ctttatttaa
    25981 aacgatgtta ttgtcttgcc aacttgaatt taacattgga tgttttttaa gtgcttgggc
    26041 cactgcttta acaaagaatg ggaagtagga taattttaag ccttcagttt gcataaattg
    26101 ggattttgtt ttttcacgta acgctacgat attacttaca tctacctcaa tttgcatcca
    26161 agcatgtgga atctcagtca ctgattgaac cattttctta gcaatggcct ttcttacccc
    26221 atctgctttg ataatttctt gttgtgagtc aagactagaa gttactggct tattattttg
    26281 ctcagattta agctcaggtt gaggctgagg atcaagcgag gtttggacta gttctggttt
    26341 tagttccttc acttgggtcg gcttgttttc agcactcgtt ggctcatagt ttatgacgtc
    26401 tttacgagta attctgccac ctttaccagt acctactatt tgacttaaat caatcccgcg
    26461 ttcttgagca atatgtaaaa ccgcaggcga gaatctaccg cctttagaat gattgcttgg
    26521 cttagcactc gctcttgatt ctgcttggct tggcgtcgtt tcaagggttg gtttactctc
    26581 aacttcaggt tcactgcttt catcagagcc agactcacct tcacctgcta cctctatcac
    26641 taaaatttcg gtaccgattg ggacggtttc gtcttcttga attagaattt ctttcaccgt
    26701 tccttggtag tcactcggaa tctctgtcgt taccttgtca gattgtgctt ctaataaggt
    26761 atcatatttt tcaacttggt cgcctacttt aacttgccaa gcaacgaccg ttgcttcagt
    26821 tacactttcg cctaaattag gcattttcac tttaactaat cccatgattt tcctcctctt
    26881 agaattcagc tagctcgcgc atggccgcca tgactttttc ttcattaatt aagaattcac
    26941 gttcaagatt taaagcataa cccatggatg gcacatctgg tccggctaac cgtttaatcg
    27001 gagcatcaag atcaaacaag gcttcttctg caataattgc ggcaatttcc ccgataatcg
    27061 ctccttcttt attgtcttct gaaacaagta agactttacc ggtcttttta gccgcttcta
    27121 tcaaggtttc tttatcaagc ggatagatag agcgaacgtc aaccacatgt gcttgaatgc
    27181 cttcttccgc taatttttct gccgcattca aggcatggac taaggccata ccatatgcaa
    27241 tcaccgtaat atcatcccct tgacgaacca catttgcctt gtctaatggt actacataat
    27301 cactttcagg cacctcagct tttaataaac gataaagacg tttatgttca tagaatagga
    27361 ctggatcatc tgaacgaatt gccgctttaa tcagtccttt agcatcataa ggatttgatg
    27421 gggttacaat tcttaaaccg ggttggccga agaagacttt ctcagttgat tgggagtggt
    27481 ataagcctcc gcgaacacct ccaccataag gggtacggta aacaattggc gcagtccaat
    27541 cacctttagt ccgataacgc atccgtgatg cttcagagat aatttggttt gtcgctggta
    27601 gaatataatc agcaaattga aattctccga tagctcggta acccattacg cctaaaccta
    27661 ccgccaagcc cccaatttca ccttcagtaa gtggtgtatt gaagcaacgt tggtcaccga
    27721 atttagcggc caagcccttg gttaccccaa aaacgccccc tttttctcca ccgacatcct
    27781 caccaaaaat gactactttt tcatctcgtg ccatttcttc ttcaataccc ttattaatcg
    27841 cttctaaata tgtaagaatt gccattgttc tttcctcctt cttaactaag cccacacttg
    27901 ttcatacaca gactctggac taggatctgg ctcagcctct gcttcatccg tagcttgatt
    27961 gatttccgct ttgaggtccg cgtcaatttg atccatttct tcccggctta aatacttttc
    28021 ggcaattaat tgtttttcaa acacattcaa tggatccttg tcttttaggc catcaatttc
    28081 ttctttagac cgataaattg attggtcatc gtcagcagag tgtgaagtta accgactcac
    28141 cactaactca attaaggtag gtccttcacc cttacgagcc cgttcaactg cttctttaaa
    28201 agctaagtaa gtggccgtga aatcattacc atctatcgta acacctggga aaccataagc
    28261 tggaccacgg taagagaaat catcattggc atattgttcc cggttggcta ctgaaatagc
    28321 ataaccatta ttttccacaa caaagataac tggtaatttc ttcacaccgg cgaagttcat
    28381 cgcttcttga acttctcctt ggttggctga tccttctccc gtagttacta gcgcaacata
    28441 atccttacct tccaattgag cggcatagcc aacaccggtc gctaaaggaa tttgggttga
    28501 tacagtagat gagtgagata caatattatg ttccttagac ccatagtggt ttggcatttg
    28561 gcggccatga gagcttggat ctgcttcctt accaaaggtc cccatcacaa tatctttaga
    28621 tgtcatgccc caaaccaaac aagccgtcat atctcggtag taaggcaaga aataatcttt
    28681 ttttgggtca aaagccattg ccatcgctac ttgggcgagt tcagctcctt gaccggaaat
    28741 attaaaggat gattttccaa tccgagtgag ttgccataaa cgttcatcta aacgacgtcc
    28801 tcttaagaca tgtttgtaaa cttcaataat ttcttcttta ctcaatccgc tttttgctaa
    28861 cttttccata gatagtcctc ctttatttat gaaccgcttt ttgatatgca tccaaactag
    28921 cttcttggat tacttcagat aaggttgggt gagcatgaac tgcttgccct acttcgagtg
    28981 ggctagcgtt cagatacatt gctgtagaaa cttcagaaag taaattcgta acttgtgggc
    29041 caatcattga taccccgatg aggtcatcac tttctgcatc acgtaacact tccgcaaagc
    29101 caatggcatc tccgtgtatt agggccttac catttcccgc aaagggaaaa ttacccactt
    29161 ttagtgaaat tgaggctgga acattgtcct tatgataacc tacactcgca atttccggtg
    29221 aggcgtaagt acaacgaggg atttgattat aatccaagct gtcattcttt ccggtcaaga
    29281 tatggtcaat tgccaattcg ccctctttca tcgcaacgtg ggctaattgc atacttggaa
    29341 tacaatcacc aatagcatat atgtggtctt ccgcggtttg ataatgctca tttacttgaa
    29401 ttcctttttg gtcaaactta atcgatgtat tttgtaaccc aattgaatcc acattcgctt
    29461 gccgaccgac agccaccaat aaccgatcaa aatgtaaggt tgtatcatcc cccttgactt
    29521 gaactgcaac ttgttggtct accactttag cactttctac ctgagcttga gttcttacgg
    29581 taataccttt tttgcttatt tcttgagtaa ataatttgga cactgctttt gactcagtaa
    29641 ttaataagcg ctcagcaaat tcaaagattg tgacttcaac gcctaaagaa tttaagaaag
    29701 atgcaaattc acaaccaata acgcccccac caataatagc cattgacttt ggtaaagttt
    29761 ccatttcaag taagccatct gaagataaaa tatactcttc atcaaaggga atattcggca
    29821 aacttttagg tcttgaaccg gtcgcgataa ttaatttttt tggaataatc acttcttctt
    29881 ggccagcttc atctgttaca ata
//
