LOCUS       c00049_NZ_OFSM..       15867 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_OFSM01000006.1 Acetatifactor muris isolate GP69, whole genome
            shotgun sequence.
ACCESSION   NZ_OFSM01000006
VERSION     NZ_OFSM01000006
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:34:13
            Original ID  :: NZ_OFSM01000006.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 224118
            Orig. end    :: 239985
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15867
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[234118:238774]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14656
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..15867
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15867
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             complement(1154..1669)
                     /locus_tag="ctg49_191"
                     /transl_table=11
                     /translation="MASLGALRSELNYWNSQVNELNGKIRKLNRRKADVNSVKTALNSN
                     VNRNSSDVNGKIRNTSNKLDKGIDYSGKDGQLNGILSGKNEQSVGGDGSLASADSEIQR
                     EINEVERQLNDARGDLSRAQDKVQSTRQAIADEERRQREEERRRREEERRQREEEARRA
                     AEARANSR"
     CDS             complement(1686..1982)
                     /locus_tag="ctg49_192"
                     /transl_table=11
                     /translation="MAGNVTHLDTAHFNETMTAYANYIRQFEGIVRDVKSATDTMAENW
                     KGKGRNAFVKDCKQVQLNLKDISDIMYDLRDALVDAEATYVKTDAALSKNFES"
     CDS             complement(1984..6585)
                     /locus_tag="ctg49_193"
                     /transl_table=11
                     /translation="MNVQKYILTILNSSIFREVDVYPDTSPLKIGTLQDCDVRLKRELF
                     AEPVCVTLLYGEGEWRAACAEGLCIHSPSVKDSKETVIRHGDIIEIHSAGSGAVLFSMS
                     FSYDFTLNSTDFDTIVDVRNISRLVIGNSPDAQIKLESAYIGSEYITLDRRPDGGYDVD
                     AGHAPASATLNGIRLFGKAQAGEYDFIGIADYSFYFKNQVLYTAKREDMRMSGISSQPL
                     REETPAFDYPKLNRSPRMLYDFDTRPVEILNPPQKPDKPRDNLVLQLSPALLMMAVTVL
                     TRSGLIGGTASGNPTFLIFSVATMAVGIVTSVISFIHNRKRYEKDLAEWNQDYAAYVSA
                     KRQEIEAGQDRERSALNDIYPGPEKERDFVKTFSGRLFERSLGDADFLHVRAGLGAVPA
                     KREITYQQEEHVKVENELMSVPVQLHEEYSMIKDAPVLLHLREAGAVGVIGSTGEQYAF
                     FKSMLLDICVLHSYEEVQIIVLLPREEQKRYEWIKWFPHIKESGGGMRGIVCDDESRDN
                     VFEYLYALMAERKAAAEGAERSVPLPHVVVFVLEEYAIKTHPLSKYADQSAECGVSFVY
                     FKEYKENLPQYCGEIVELTQTGGTLRLRNDKEFACPFVREEVSDDSIRFAAERLAPVYC
                     EKIALSSRLTSNITLFELLNILSPEDLNLSERWSRANVQKSLAAPLGVDVKGSRIFLDL
                     HEKAHGPHGLVAGTTGSGKSEIMQSYILSAAVNFHPYEVSFVLIDFKGGGMANQFENLP
                     HLIGKITDIDSHEMNRSLLSIRAELEKRKRLFAEYEVNHIDQYIAKFRSGETKTALPHL
                     ILIVDEFAELKAEQPEFMKELISTARVGRSLGIHLILATQKPAGQVNEQIWSNSKFKLC
                     LKVATKEDSNEVLRSPLAAEIREPGRAYLQVGNNEIFTLFQSAYSGASAISDKNGNMRE
                     FSVSEVSFTGKRTVVYERKAQQSGDGSRITQLKAMIQYMDQYCRDACIPRLPSICLPPL
                     PEVIDYPEGGENACTGICVPVGVYDDPANQIQPPVSLNLSQGNIMIVGSAQTGKTLLLQ
                     TILRGIAENYDPGQVAVYVLDFASKVMKIYEGLNHVGGVLTDADDEKLKNFFKMIREEI
                     ADRKETFSQLGIGSYETYLEQTPSPDKPQIVIMIDNLAAFKELFQEYEDAMLNICREGL
                     ALGVTVIATAKQMMGLSYKYLSNFATRLAFNCTESSEYNNIFDRCPIRPGNVQGRGLVS
                     IEKTVYEYQVYLPFDGIVETGGEQRRTEGRRIEQAKEFVNRISARYGKRRARAIPAIPP
                     VLTAEYWEGEEFAPYVIPVALTYSEIEPVTVDLAHVGTLGIYGREGFGKSNLLRSVLTY
                     LQRHVFDLPCEAYLIDGYDRQLAEFETCGFVEQFTVDCADFEEIVLRFADRAKERMEIL
                     RMGGSLEEEPLLLCVVQNPQIFTAGTIPKPVCEQFRKLLPEAKQLKICFIFSNVDNNGE
                     FTPPDMMKIVRDFQQFFFLDDMANVKLFGANKFSSTDLKPYKKPISLGDGYWYEARNGI
                     EKVKMVKCEEGSL"
     CDS             complement(6589..6840)
                     /locus_tag="ctg49_194"
                     /transl_table=11
                     /translation="MAANKAIITLNLVSMGISHDLEVPLDISANELCAALFQRYMPDRD
                     SDVQQYYLKSERPIALLRGERTLREYGLRDGSVINITR"
     CDS             7376..8605
                     /locus_tag="ctg49_195"
                     /transl_table=11
                     /translation="MTELINRPEYLNQLIQNKDVNLVKIVSGIRRCGKSSLLDLFHQYL
                     SDSGIEDSHIIHMNLESLRYRNLSDYLAFYDYVSGRIPDTGRTYLIFDELQAVEHWEKA
                     IESFRLDFDVDIYITGSNAYLLSTEFSTLLSGRYVEIRMLPLSFKEFLTFYEFAPSVTA
                     EEKFHRYLQFGGMPILREYRFNEARSIQALEGIYATVVLRDILQRNNQTDQRILHKIVL
                     FLCSNVGSITSPNSIGNVLSNEGDIQNGKGKNVAGKTVEKYISLLRSAYIFYSIGRYDV
                     KGRQLLKTLGKNYIIDMGFRNMLLGYRDADRGHILENIVFLELLRRDYRVYIGKVGGTE
                     VDFVAEKPNDKLYIQVTESMQSPETRERELRPLRLIPDNYEKIILSMDRNYITSYDGIK
                     SLNLIDWLLA"
     CDS             complement(8804..9133)
                     /locus_tag="ctg49_196"
                     /transl_table=11
                     /translation="MEHNIYLYILTAAAVSCLIRVLPLTLIRKKIKNPFLRSFLYYVPY
                     VTLAVMTFPAIIAAPQIPLAGILALIVGVIAAWKGVNMIGIAALCCFVVFVCEAVVLHL
                     NSLAR"
     CDS             complement(9123..9878)
                     /locus_tag="ctg49_197"
                     /transl_table=11
                     /translation="MEQNRRAFRDGIRDGFPIALGYFAVAFSLGIAARKAGLNPFQGFL
                     SSILNHASAGEYAEFTVIMANAAYFEMAFVILVTNMRYLLMSCALSQKFDPTTSGIHRF
                     LVGFGITDEIFGIGIARKGVVNPWYHYGAMAVALPSWAAGTAIGIVAGNILPVSAVSAL
                     SVALYGMFVAIIVPASRKDKTVGGVVAVSFLASFLVSRIALFDGLSESMKISLLTVLIA
                     GIAAAFFPVKEEADKEAETRTEKGRRHGA"
     CDS             complement(10001..11260)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_198"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 1.9e-42, bitscore:
                     139.8, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 3.5e-35,
                     bitscore: 114.8, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEIVIIGCGGVASVAIQKCAKKADVFSEICIASRTISKCDALKE
                     KLEGTTEAKITTAKVDADNVEELIALLKKEKPKAVLNLALPYQDLTIMDACLACGVDYI
                     DTANYEAEDTEDPEWRAAYEKRCKEAGFTAYFDYSWQWAYRERFEKAGITALLGSGFDP
                     GVTSVFSAYALKHYFDEIHRIDILDCNGGDHGYPFATNFNPEINLREVSANGSYWENGH
                     WVETKPMEIKREYDFAQVGKKDMYLLHHEEIESLAKNIPGIQRIRFFMTFGQSYLTHMK
                     CLENVGMLRTDPVVFEGREIVPIQFLKTLLPDPASLGPRTVGKTNIGCIFTGVKDGKEK
                     SVYIYNVCDHQECYRELGSQAISYTTGVPAMIGAMLVMKGTWKRAGVFNVEEFDPDPFM
                     EALNEYGLPWVVEENPVLVD"
     CDS             complement(11342..12199)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_199"
                     /sec_met_domain="Spermine_synth (E-value: 4.2e-57,
                     bitscore: 186.3, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 2.6e-17,
                     bitscore: 56.2, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWFSEPHTPDVKLSIRVDKQLYSGESDLQRIDVFESPELGRFL
                     VLDGYVMLTEKDEFIYHEMIVHVPMAVHPCVKRVLVIGAGDGGVVRELTRYPEIEYIDL
                     VEIDQQVIQVCRDYLPRTACKLDDERVYIHYEDGLKFVRTREDEYDLIIVDSTDPFGPG
                     EGLFTKEFYGNCYKALREDGIMVNQHESPFYEADATACMRAHKRIVESFPISRVYQAHI
                     PTYPSGHWLFGFASKRYHPVRDLDAARWDERGLETKYYTTRLHMGAFCLPAYVEKLLRK
                     VEIR"
     CDS             complement(12363..13823)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg49_200"
                     /sec_met_domain="OKR_DC_1_C (E-value: 1.5e-13, bitscore:
                     44.9, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 3.3e-124,
                     bitscore: 408.2, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRFNQSRAPIYEALEEFRRDRIVPFDVPGHKRGRGNPELAALLG
                     QQCVGIDVNSMKSLDNLCHPVSVIREAEEMAAEAFGAAYAFLMVGGTTSSVQSMVLSAC
                     KKGDKIILPRNVHRSVINALVLNGAIPIYVNPDMDSRLGIALGMKVSQVERTIQEHPDA
                     VAVLVNNPTYYGICSDLRSIVCMAHAHGMKVLVDEAHGTHFYFGEKMPLSAMEAGADMA
                     AVSMHKSGGSLTQSSFLLTGIGMNPGYVRQIINLTQTTSASYLLLASLDISRRNLALRG
                     KEQFAKVISLAEYAREEINRIGGYYAYTAELINGDSIFDFDRTKLTVNTLGIGLAGIEV
                     YDLLRDEYDIQMELGDIANVLAYLSIGDRERDMERLIGALVEIRRKYGRDNTGMYTQEY
                     IEPKVAVSPQNAFYAEKESLPLSETEGRICSEFVMCYPPGIPILAPGEEITAQILEYIT
                     YAREKGCSMTGPEDPAIERLNVLKEEWM"
     CDS             complement(13898..14656)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: AdoMet_dc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_201"
                     /sec_met_domain="AdoMet_dc (E-value: 1.2e-31, bitscore:
                     102.8, seeds: 266, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEKFTLYGFNNLTKSLSFNIYDVCYAKSQREQKDYIAYIDQQYN
                     SERLTKLLVDVTEMIGATVLNISSQDYEPQGSSVTILIADESKVPMGDTTVAHLDKSHI
                     TVHTYPEYHPDTCLATFRVDIDVATCGEITPLSTLDYLIGAFDSDIITMDYRVRGFTRD
                     VSGQKLFMDHRITSIQDYIDQNTMRRYDAVDINVYEANIFHTKMLIKEIDLQNYLFNSD
                     VYELPPKLRLEIMDNLRREMIEIFSGRNIY"
     CDS             complement(15168..15518)
                     /locus_tag="ctg49_202"
                     /transl_table=11
                     /translation="MNLNTSKINLPGLWDVIRAYEGKQFLTKKGLPFTYTIKGGELFTD
                     RRERSITRSTFEKAYEKLIQDQTGENAPKKIVGPKTLNVYGAPYVWAVFMGIGLIEETV
                     YVQLAIEPKQED"
     CDS             complement(15636..15866)
                     /locus_tag="ctg49_203"
                     /transl_table=11
                     /translation="YTPKHGSWLDIAEIELNVMTRQCLSRRIADIELLRSELSVWETER
                     NTTAAKVDWHFRTGDARIKLKSLYPSFTAAS"
ORIGIN
        1 atttcagcgt cactttcttg atcggcttac cgtcggaacc ccgggccagc tctttgaagg
       61 caaatcctac cccgttcttg ctaaggaagc ttcccgcaat cttcccgatg gaatgtacca
      121 gggtaatgac gcccgctatg gtatccgtaa tctcaatggc gcttgccgcg gtataggagg
      181 ccctgttcaa ctctctgtta tggaaattat gctcccgcag cacctgggcc agggtatccc
      241 gctccccgta tattttggcc attgcagggt cacccccctg actggcggta atggcctgta
      301 cagaggtaac gatattcgtc accgcattga ccgcggcaat cactgcagtg acacaggccg
      361 ccacagcaaa tagaatcgcc cctcccgtaa tcaccgtggc tgtggccagg gccacaacgg
      421 cagcaactgc ggtaagcaca gccgccacag ctgcgccgat tttaatcaca atgtccaggc
      481 agttcataat cagctctttc ccgccgccgc atttccacca gtgcttaatc tctctcccca
      541 gcgcatcgat tgcatttaac gcatcctctc cgccctgaat cagccagccc agaaccggca
      601 cattcttcat atcacagata aaggtagtcc aggcctgctt gtaccagggg gccttaagct
      661 ccggattctt ctggaaaaag gattcctgat tgtcctgaat catcctttcc acatcttcgt
      721 ccacccgctt cgccgtgtcg accagctcct gtatcttccc ggaaagggtg cgggcactgt
      781 cttcccggtt ccgcagctgt gtaatcttct ggttgacata gtaatccgca ttgctcagcg
      841 cggacgacat tccgccttcc accgaataca ttttctgctg aaccttccgg ctcagatcct
      901 cacagtactg attcagttcg tcggccagcc gattcgcctc ggttgccgca cctgataagt
      961 ccccatatct taatgagaga accacttttc taccccctgt tgcaatttct atgtatccct
     1021 gtctctttcc ccaccgcgcc tgaaagcttt gacgcagctc catgcttccc gctcctgcag
     1081 gacagctcat ttccggaaac cgtcgttcat ttcctgcgcg gctcttctta tcactgctca
     1141 gatttccggc tcattaccgg gaattggctc tggcctccgc cgccctgcgg gcttcctcct
     1201 cccgctgccg cctttcctct tcccggcgtc ttctttcctc ttcccgctgt cgtctctctt
     1261 catctgcgat ggcctgcctg gtgctttgaa ctttatcctg ggctctggac aggtctcctc
     1321 tggcatcgtt cagctgccgt tccacctcat tgatctcacg ctggatttca ctgtccgcag
     1381 aggccagact cccgtcacct cccacggact gctcgttctt cccggataaa ataccgttca
     1441 actgaccgtc tttacctgaa taatcgattc ctttatccag cttatttgac gtgttacgga
     1501 ttttgccgtt cacatcgctg gaattcctgt tgacattgga attcagcgct gtctttaccg
     1561 aatttacatc tgccttcctt ctgttcagct ttctgatctt cccattcagc tcatttacct
     1621 gactgttcca atagttaagc tcactgcgga gcgctcccag actcgccatt ttccctcacc
     1681 cgccttcacg attcaaaatt cttcgacagc gccgcatctg tcttcacata tgtggcctcc
     1741 gcgtccacaa gcgcgtcacg cagatcatac atgatgtccg aaatatcctt cagattcagc
     1801 tgtacctgtt tgcagtcctt cacaaaagca ttgcgccctt tgcccttcca gttctccgcc
     1861 atggtatccg tggcagactt cacatcccgg acaattccct cgaactgtct gatataattg
     1921 gcataggcgg tcattgtctc attgaaatgg gccgtatcaa gatgtgtcac atttcctgcc
     1981 atgtcacaga ctcccttcct cacactttac cattttaacc ttctcaattc cgttccgggc
     2041 ttcataccag tacccgtctc ccagagaaat gggctttttg tatggcttca gatcggttga
     2101 cgagaattta tttgcaccga aaagtttgac attcgccata tcgtccaaaa agaagaactg
     2161 ctggaaatca cggacaattt tcatcatatc cggaggcgta aattctccgt tgttatccac
     2221 attggagaag ataaaacata tcttcaactg ttttgcttcc ggcagcagct tccggaactg
     2281 ctcgcacacc ggcttcggaa ttgtccccgc cgtgaaaatc tgtggattct gaaccacaca
     2341 gagcagcagc ggttcttctt ccaggcttcc gcccatgcgg agaatctcca tacgctcctt
     2401 cgccctgtca gcgaatctca gaacaatctc ttcaaagtcc gcgcagtcca cagtaaactg
     2461 ctccacaaaa ccacaggtct cgaactccgc cagctgtctg tcatatccgt ctatcagata
     2521 agcttcgcag ggcaggtcaa acacatgcct ctgcagataa gtcaggacag accgcagcag
     2581 attgctcttg ccgaatccct ctcttccata gattccaagg gtacccacat gggccagatc
     2641 caccgtcacc ggctctatct cgctgtaggt cagagccaca ggaatcacat aaggcgcaaa
     2701 ttcctctccc tcccaatact ctgccgtcag cacaggcgga atggccggaa tggctctggc
     2761 ccgccgtttg ccgtatctgg ccgatatcct gttcacaaat tctttcgcct gctcaatacg
     2821 ccggccttcc gtccgcctct gttcgcctcc tgtctccaca atgccgtcaa aaggcaggta
     2881 tacctgatat tcatacactg tcttctcaat ggaaaccagc ccccggccct ggacattccc
     2941 cggccggatc ggacaacggt caaaaatgtt attatactca ctgctttccg tacagttaaa
     3001 ggcaagcctt gtggcaaaat tactcagata tttatagctg agtcccatca tctgcttcgc
     3061 ggtggcaatg acagtgacgc ccagggccag cccttcccgg cagatattca gcatggcatc
     3121 ctcgtactcc tggaaaagct ccttgaaggc agccaggttg tctatcataa tcactatctg
     3181 cggcttatcc ggcgaaggtg tctgttccag atacgtctca taggagccga tgcccagctg
     3241 ggaaaatgtc tccttgcggt cggcgatttc ctcccgtatc attttgaaga aattcttcag
     3301 tttctcgtcg tcggcatctg tcagcacacc gcccacatgg ttcagcccct catagatttt
     3361 catcaccttg gaggcaaagt caagaacgta taccgccacc tgaccggggt cgtaattttc
     3421 cgcaatcccg cgcaatatgg tctgcagcag caatgtcttg cccgtctgcg ccgagcccac
     3481 aatcatgata ttcccctgag acagattgag acttacggga ggctgtatct gattggccgg
     3541 atcgtcgtac acgcccacag gtacacagat ccctgtacag gcattctccc cgccctccgg
     3601 ataatcaatc acctccggca aaggcggcag acaaatgctg ggaagcctgg gaatgcaggc
     3661 atccctgcag tactggtcca tatactggat cattgctttc agctgggtaa tccggcttcc
     3721 gtcaccggac tgctgtgcct tccgctcata gaccaccgtc cgtttcccgg taaaggatac
     3781 ttccgagacg gagaattccc gcatattacc gttcttgtca ctgattgcgg acgcaccgct
     3841 gtaagctgac tgaaacaatg taaaaatctc attattgccc acctgcagat aggcccggcc
     3901 cggttctctg atttccgccg caagagggga acgcagcact tcgttgctgt cttccttcgt
     3961 ggccaccttc agacacagct tgaatttcga attgctccat atctgctcat ttacctggcc
     4021 tgccggcttc tgggttgcca atataagatg aattcccaga ctgcgcccca cccgggccgt
     4081 actgatcagc tctttcatga attccggctg ttccgccttc agctccgcga actcatccac
     4141 aatcagaatc agatgcggca gcgccgtttt ggtttctccc gaccggaact tcgcaatata
     4201 ctgatcgata tgatttactt catactcggc aaataaccgc tttctctttt ccagctccgc
     4261 ccgaatggac agcagagagc ggttcatttc atggctgtct atatccgtga tcttcccgat
     4321 cagatggggc aggttctcga actgattcgc catgccgccg cccttaaagt ctatgaggac
     4381 aaaggatact tcatagggat gaaaattcac cgccgctgaa agtatgtagg actgcatgat
     4441 ctcacttttt cctgagcctg tggtacctgc caccagacca tggggaccgt gagccttctc
     4501 atgaagatcc aggaaaatcc tgctcccttt cacatccacg cccagcggtg cggcaaggga
     4561 cttctgcaca ttggctctgc tccagcgttc cgacaggttc aaatcctccg gcgacagaat
     4621 gttgagcagc tcaaacagtg tgatattgga tgtcagcctg gaagaaagcg caatcttctc
     4681 acagtatacc ggtgccagcc gctccgccgc aaaacggatg ctgtcgtcac tgacctcctc
     4741 ccgcacaaag ggacaggcga attccttgtc atttctcagg cgcagcgttc cgcctgtctg
     4801 cgtcagttcc acgatttcac cgcagtactg gggcagattt tccttatatt ccttaaaata
     4861 gacaaagctt accccacact ctgcggactg atccgcatat tttgacagcg ggtgcgtctt
     4921 tatggcatat tcctccagca caaaaaccac cacatgcggc agaggcacag acctctcggc
     4981 tccctcggcc gccgctttcc gttccgccat cagcgcatag aggtactcga acacattatc
     5041 ccggctctcg tcatcacaga caatcccccg cattccgccg ccggactcct taatatgcgg
     5101 aaaccatttt atccattcat accttttctg ctcctcccgg ggcagcagga caataatctg
     5161 tacctcctca taactgtgca ggacgcagat atccagaagc atacttttga aaaaagcata
     5221 ctgctctccg gtcgaaccga ttacgcccac agctcccgct tccctcagat gcagcagcac
     5281 aggagcgtcc ttaatcatcg aatattcttc gtgaagctgg acgggaactg acatcagttc
     5341 attttccacc ttgacatgct cttcctgctg atatgttatt tcacgcttcg caggaaccgc
     5401 ccccagacct gctctcacat ggagaaaatc ggcatctccc aaagagcgct caaacagccg
     5461 cccggaaaac gttttcacga aatcccgctc tttctccggc cccggataga tatcgttcag
     5521 cgcggaacgc tccctgtcct gcccggcctc gatctcctgc cgtttggcac ttacataagc
     5581 ggcataatcc tgattccatt ccgccaggtc cttctcatat cgcttcctgt tatggataaa
     5641 gctgatcaca gaagtgacaa ttcccacggc catagtggca acactgaaaa tcagaaaggt
     5701 cggattgccg gaagccgttc cgccgatgag accgcttcgg gtcagcaccg tcacagccat
     5761 catcagcagc gccggagaca gctgcagcac aagattatcc cggggtttgt ccggcttctg
     5821 cggcggattt aaaatctcca ccggcctcgt gtcaaaatca tagagcatac ggggactgcg
     5881 gttcagcttc ggatagtcaa aggccggcgt ctcctcccgc aaaggctgag aagaaattcc
     5941 ggacatgcgc atgtcttcac gcttcgccgt atacaaaacc tgattcttaa agtaaaaact
     6001 atagtcggca atcccgataa aatcatactc tcctgcctgc gctttcccga acagacggat
     6061 cccgttcagc gttgcgctag caggcgcatg gccggcatcc acatcgtacc cgccgtccgg
     6121 cctgcggtcc agcgtaatat attcgctgcc tatatacgca ctctcaagtt ttatctgagc
     6181 atccggcgaa ttgccgatga caagacggct gatgttacgc acatcaacaa tcgtatcgaa
     6241 gtctgtagaa ttcagagtaa aatcatagga aaaagacatg ctgaacagca ctgcaccgct
     6301 gccggcactg tgtatttcaa tgatatctcc atgacggatt accgtttcct ttgagtcctt
     6361 cacactggga gaatgaatac acagtccctc cgcacaggcg gcgcgccact ctccctcccc
     6421 atacaggagt gtaacacata ccggttctgc aaataattcc cgcttcagcc tcacatcaca
     6481 gtcctgcaat gttccaattt taagaggaga ggtgtccggg tacacatcca cctctctgaa
     6541 aatactgctg tttagaatgg tcagtatgta tttctgtaca ttcattgatt acctcgttat
     6601 gttgattacg cttccgtcac gaagcccata ctcacgaaga gtgcgctcgc cgcgcagcag
     6661 cgcaatcggc cgctctgact tcagatagta ctgctgtaca tcactgtccc tgtcaggcat
     6721 ataacgctga aaaagcgcag cacataattc attggccgag atatccaacg gtacttccag
     6781 atcatggctg atgcccatac tcaccagatt caatgtaata atcgccttat tcgccgccat
     6841 ccactgcctt ccccttcgct gtgtttattt cagattttct aaataatgta taaacattat
     6901 aaataaattg taagtttttg tcaattattg tttctaaatt tgggcaattt agtccaaacc
     6961 attcaaatac aaaacgccac ataattttcc gtcacggctc ccataaacag acttccttcc
     7021 cctgataaaa tggtctgccc ggacatgcct gctttcatga caaggagccc cgtatcagcc
     7081 atatttcagc cattcaatgg atgcgccgaa aatggcggca ctcccgccct tctgcactac
     7141 tttatactga aattttctat tctcctttgc cagctgagca ggaatggcct gtcaagaatc
     7201 ccattctgca ccatagttac gtccagaaaa cttttatgct ccaaaaacgc attgttttct
     7261 gtctctatat gtcaaaaact actgtatttc atttggtttc cgactcgcaa gtccgaaact
     7321 cttgtatttt ttcaattata gggtataata aaaaatagaa attaggaggt gcgtcatgac
     7381 cgaactgata aatcgacccg aatatttaaa tcaactcatt caaaataaag atgtgaatct
     7441 ggtcaaaatt gtctccggca ttcgcagatg tggaaaatca tccctgctgg atctgtttca
     7501 tcaatacctg tctgacagtg gaatagagga ttctcacatc attcatatga acctggaatc
     7561 tctgcgctac cggaatcttt ccgattacct tgctttctat gactatgtca gcggacgcat
     7621 tccggacacc ggaaggactt atctgatttt tgatgagctt caggctgtgg aacattggga
     7681 aaaggctatc gagtctttcc gcctggattt tgatgttgat atctacatta ccggttccaa
     7741 tgcttacctg ctttctacgg agttttccac gctgctttcc ggcaggtatg tggaaatccg
     7801 tatgttgccg ctgtctttta aagaatttct gaccttctat gaatttgctc cttctgtcac
     7861 agcggaggaa aaattccata gatatcttca gtttggcggt atgcccattt taagagaata
     7921 caggtttaac gaagcgagaa gcattcaggc actggaaggt atctatgcaa ctgtagttct
     7981 acgcgatatt ctccagcgta acaatcagac cgatcagaga attctgcaca aaatcgtact
     8041 gtttctctgc tccaatgttg gcagcatcac atcacccaac agcatcggta atgtcttgag
     8101 caatgaaggt gacattcaaa acggaaaagg aaaaaatgtg gcgggtaaaa ctgtggagaa
     8161 atacatttcc ctgctgcgca gcgcatatat cttctactct atcggcagat atgacgtaaa
     8221 aggcaggcag ctactgaaaa cactgggaaa aaactacatc attgacatgg gattccgcaa
     8281 catgctgctt ggctatcgcg atgcggatcg gggtcacatt ctcgagaata ttgtgttcct
     8341 ggaactgctt cgacgtgact accgtgtgta catcggaaaa gtagggggaa ccgaagtaga
     8401 ttttgtagcg gaaaagccaa atgataagtt atatattcag gtaacagaaa gtatgcaatc
     8461 cccggaaacc cgtgagcgcg aactaagacc tctgcgcctg atacctgaca actatgagaa
     8521 aattattctg tcaatggatc ggaattatat cacttcttat gacggcatca aatctttgaa
     8581 tttgattgac tggctgctgg cctgaatttg aaattcctta acagttgtgt actatcttct
     8641 cctgccttcg tttatgaaga gcaggagaag cacagcgcag gcggttagtc cttctaaatt
     8701 aaactgttcg atcatgaatc ataccggaat ccatgaggtt aatcttctac agcggccatg
     8761 aaaaatagga gttgatgaaa gactccagct tttaaagtcc tctctacctt gccaaagaat
     8821 ttaaatgcag aaccacagct tcgcagacaa ataccacaaa acagcacagc gcagcaatcc
     8881 cgatcatgtt gacacctttc catgcggcaa tgacacccac aatcaatgcc agaatcccgg
     8941 caagcggaat ctggggtgcc gcgataatcg ccggaaaagt catcacggcg agagtcacat
     9001 acggaacata gtaaagaaat gaccgcagaa agggattctt aatcttcttc cgaatcagcg
     9061 tcagaggcag tacacgaatc agacaggata cggcagccgc tgtcaatatg taaagataaa
     9121 tgttatgctc catgtctccg tcccttctct gtcctggtct ccgcctcttt atcggcttcc
     9181 tccttcaccg gaaagaaagc cgcggcaatc ccggcaatca gcactgtgag caggctgatc
     9241 ttcatgcttt ccgacagccc gtcgaacaga gcaatcctgg ataccagaaa gctcgcgaga
     9301 aagctgaccg caactacgcc ccccacagtc ttatccttcc tggacgccgg aacgataatc
     9361 gccacaaaca taccgtataa cgccacactc agcgcgctga ccgcagaaac cggaagtatg
     9421 ttgcccgcca caatccctat ggcagtacct gccgcccagc tgggaagggc gacagccata
     9481 gccccatagt gataccaggg attcaccact ccttttctgg caatgccgat tccgaagatt
     9541 tcatctgtaa ttccgaagcc caccaggaac cgatggatgc cggaagtcgt cgggtcgaac
     9601 ttctggctca gcgcacagct cataagcaga tagcgcatat ttgtcaccag aatgacaaag
     9661 gccatctcaa aataggctgc attcgccata atcacagtaa attcggcata ttctcctgcg
     9721 gaagcatgat ttaatatact ggataaaaat ccctgaaaag ggttcaaacc agctttcctc
     9781 gccgcgattc ccagagaaaa tgccactgca aagtatccca gcgcaatggg aaaaccatct
     9841 ctgattccgt ctcggaaagc ccttctattc tgttccattt tatttctctt tcgccgcctc
     9901 tctcagggat ttcaagtccg ccccctatca gaatcattgt ccctttaccc cacaggcaac
     9961 agtcaggaca gctccctgag ctgttgccct ctcagtccaa tcagtccacc agcacgggat
    10021 tctcctccac cacccagggc aggccgtatt cgttcagcgc ctccataaac ggatcgggat
    10081 caaattcttc cacgttaaat acgccggccc ttttccaggt ccccttcatc accagcatgg
    10141 cgccgatcat ggcaggcaca cctgtcgtgt aggaaatggc ctgagacccc agctccctat
    10201 agcattcctg atggtcacac acattgtaaa tgtagacaga cttctccttc ccatccttta
    10261 ctccggtgaa aatgcagccg atattggtct tgcccaccgt gcgggggccc agagacgccg
    10321 ggtccggaag cagtgtcttc aggaactgga tgggtacaat ctctctgccc tcgaatacca
    10381 cagggtcggt gcgcagcatt cccacattct ccagacattt catatgggtc agatagctct
    10441 gcccaaatgt cataaaaaac cggatgcgct gaatgcccgg aatattcttc gccagagact
    10501 cgatttcctc atggtgcaga agatacatat cctttttccc cacctgagca aaatcatact
    10561 cccgctttat ctccatgggc ttcgtctcca cccagtgtcc gttctcccag taggaaccat
    10621 ttgccgatac ctcccggaga ttgatttccg ggttgaaatt ggtggcaaag ggatagccgt
    10681 gatcgccgcc gttgcagtcc aggatatcaa tcctgtgaat ctcgtcaaaa tagtgcttca
    10741 acgcataggc agaaaatacg ctggtcactc cggggtcaaa gccgctgccc agcagagccg
    10801 taatccccgc cttctcaaag cgttctctgt aagcccattg ccaggaatag tcaaaataag
    10861 cggtgaagcc cgcctcttta cagcgtttct catatgcggc gcgccactcc ggatcttccg
    10921 tgtcctccgc ctcataattg gccgtgtcaa tatagtctac cccgcaggcc aggcaggcat
    10981 ccattatggt caggtcctga tatggcagcg ccagattcag cacagccttc ggcttctcct
    11041 ttttgagcag agcaatcagc tcctccacat tgtccgcatc caccttcgcg gtagtaatct
    11101 tcgcttcggt ggttccctca agcttctctt ttaatgcatc acatttggat atcgtgcggc
    11161 tggcaatgca gatttccgag aatacatccg ccttcttcgc acatttctga attgccacag
    11221 aggccacgcc tccgcagccg ataattacaa tctcagccat tttcatctct cctctaatat
    11281 agttctacag ccttcccggt actcttaaat cctgtattca caacataata aaaagccgga
    11341 ctcatcgtat ctccaccttg cgcagcagct tctccacata agccggcaga cagaaagctc
    11401 ccatatgaag ccttgtggtg taatatttcg tctccagccc ccgctcatcc catctcgcag
    11461 cgtccaggtc ccgcaccggg tgataccgtt tggaggcgaa cccgaacagc cagtggccgg
    11521 agggataggt gggaatatgt gcctgataca cccggctgat gggaaagctc tccacgatac
    11581 gcttgtgagc cctcatacag gctgtggcat ctgcctcata gaaaggactt tcatgctggt
    11641 tcaccatgat gccatcctcc cgcagcgcct tatagcagtt tccatagaat tccttcgtga
    11701 acagcccttc tccggggccg aaagggtccg tggaatccac aatgatcaga tcatactcgt
    11761 cttcccgggt gcggacgaat ttcagaccgt cttcatagtg aatatacact ctctcgtcgt
    11821 ccagcttaca ggctgtccgg ggcagataat ctctgcacac ctgaatcacc tgctggtcaa
    11881 tctccaccag gtcgatatac tctatctccg gatacctggt cagttcccgc accacgccgc
    11941 cgtccccggc accgattacc agcacccgct ttacacaggg atgtaccgcc atgggcacat
    12001 gaacaatcat ttcatggtaa ataaattcgt ccttttccgt cagcattaca tatccgtcca
    12061 gcaccaggaa ccgtcccagt tccggggatt cgaacacatc aatcctctgc agatcacttt
    12121 ctccgctgta taactgctta tctacccgga tggacagctt cacatccggt gtgtgcggtt
    12181 ccgaaaacca taattccata aagccacctc ctattccagt tccgtatctg cccgaaagta
    12241 cacttttcct gagatacatt tccggtcgca agtacattcg tccgtaaatg tatctgtgta
    12301 cttcccgggc agatactgtt ttctaaatta agtcgctgcg cgacggctct aaagggtaaa
    12361 gtctacatcc actcttcttt caacacattc aggcgttcga tggccgggtc ctccggaccg
    12421 gtcatggagc agcctttttc tctggcataa gtgatatact ccagaatctg cgccgtgatc
    12481 tcttcccccg gcgccagaat gggaatgccg ggcggatagc acatgacaaa ttcactgcag
    12541 atacgccctt ccgtttccga taaaggcagg gattctttct ccgcgtaaaa tgcgttctga
    12601 ggagacacag ccactttggg ctcgatgtat tcctgggtat acatacctgt attgtcccgg
    12661 ccgtattttc tcctgatttc caccagggcg ccgatcagcc gctccatatc ccgctctctg
    12721 tccccgatag acagataggc cagcacattg gcaatgtcac ccagctccat ctgaatgtca
    12781 tattcatccc tgagcaggtc atagacttca attcccgcca gcccgattcc cagcgtattc
    12841 acggtcagtt tcgtcctgtc gaaatcgaag atgctgtccc cgttaatcag ttccgcggta
    12901 taggcataat atcccccgat acggttaatt tcttcccggg catattccgc cagtgatatg
    12961 acttttgcaa actgttcctt tccccgaagc gccagattcc tgcgggaaat atccaggctg
    13021 gccagcagaa ggtacgaagc gcttgttgtc tgggtcagat tgataatctg tctcacataa
    13081 ccgggattca tcccgattcc cgtcagcaga aaggagctct gtgtcaggct tccgcctgat
    13141 ttgtgcatac tgacagccgc catatctgcg ccggcttcca tggctgacag cggcatcttt
    13201 tccccgaaat aaaagtgggt cccatgagcc tcatccacca gcaccttcat tccatgggca
    13261 tgcgccatac acacaatact ccgcagatca gagcaaatcc catagtaagt agggttattt
    13321 accagtacag ccaccgcgtc cggatgctcc tgaatggtcc gctccacctg agacactttc
    13381 atccccagcg caatacccag cctgctgtcc atatccggat tcacgtatat ggggatagcc
    13441 ccgttcagca ccagtgcatt gatcacactc ctgtgcacat tcctgggcag aataatctta
    13501 tctccctttt tgcaggcgct cagaaccata ctctgtaccg aagatgtggt gccgcccacc
    13561 atcagaaaag catatgccgc tccaaaggct tccgctgcca tttcctccgc ttcccgaatc
    13621 acagatacgg gatggcacag gttgtccagg gacttcatgg aattcacatc tattcccaca
    13681 cactgctgcc ccagaagcgc agccagctcc ggattccccc ggccccgttt gtgtcccggc
    13741 acatcgaagg gcacaattct gtctcttcga aactcttcca gcgcctcata gatcggcgct
    13801 ctggactgat tgaaacgccc catctgctgt cccctccttc cccggatctg ccttccagag
    13861 tgttctctta cctttcgctc ctgtcacacc cggcacatta ataaatattc ctcccgctga
    13921 atatctcaat catctccctg cgcagattgt ccataatctc cagccgcagc ttcggcggca
    13981 gttcatagac atcgctgttg aacagatagt tctgcagatc aatctcctta atcagcatct
    14041 tggtatgaaa aatatttgcc tcatatacat tgatatccac cgcatcatat ctgcgcatgg
    14101 tgttctggtc aatgtagtcc tgaatggacg tgattctgtg gtccataaaa agcttctggc
    14161 cgctgacatc ccttgtaaac cctctgaccc tgtaatccat ggtaataatg tcggaatcaa
    14221 aggctccgat cagataatcc agcgtggaca gcggcgtaat ctctccgcag gtggccacgt
    14281 caatatccac ccgaaaagtg gcgagacagg tatcaggatg gtactccgga tatgtatgaa
    14341 cggttatatg gcttttatcc agatgcgcca ctgtggtatc ccccatgggc accttgcttt
    14401 cgtccgcaat cagaatagtc actgaactgc cctgcggctc ataatcctgg ctggaaatat
    14461 tcagtacagt ggcccctatc atctccgtca catccaccag aagtttggtc agacgttccg
    14521 aattatactg ctgatcgata taggcaatat agtccttctg ctccctctga gacttggcat
    14581 agcacacatc gtaaatatta aaactaaggg atttggttaa attattaaat ccatacagag
    14641 taaatttctc gctcatacct tctcctttat ccagacttcc atataccgga cctgtgcaaa
    14701 ataaaaagca agtgatactt acctcacttg cttttaaata tccctgctct cgttttcact
    14761 tatacccgcc gtctgattcc acgactttca agtacgaaat aacagatata tggttttaga
    14821 gtctatatag caaatatttt acttttacta ctcttattga ccgtttcaca agttagatgt
    14881 gcatctgcac cggtttatag taaccaactt ataaaatctg agctcttaac tcaatcaata
    14941 aggcaacaca gttgccaaaa tatttacatg gaagactctg tctgttttcc atacttacac
    15001 tgtcatatcc agtgtatcgc tttcactatc gctcattgta tcatgtctct tacatttcgt
    15061 caaatattat ttgtccactt tattacctgc tctgaccgcc gcgttttgcc ggcagcagtt
    15121 cggcagcctg tcttttaaca cccgcaccgt cggatgcagg atgcgttcta gtcctcctgc
    15181 ttcggctcta tcgccagctg cacatacaca gtttcttcta tcagcccgat gcccatgaac
    15241 acagcccaca cataaggcgc gccgtacacg ttcagcgttt taggtcccac gatctttttc
    15301 ggcgcattct cgccggtctg atcctgaatc agcttttcat atgctttttc aaaagtactt
    15361 ctggtaatgg acctttcccg cctgtctgtg aacagttccc cgcccttgat ggtataggta
    15421 aacggaagcc cctttttggt taaaaactgc tttccctcgt atgcccgaat cacatcccac
    15481 aggccaggga gatttatctt cgatgtatta agattcatat gcctcctcgc tccgtaacac
    15541 acccctgaaa tcagggccgg ttcccagcgg cgctatcggt ctatgccgtt atactagtgt
    15601 attgacatga cgatatttaa ccttactacc gccttttaag aggcggcagt aaagctgggg
    15661 tataaagact tgagctttat tctggcatca cctgtcctaa aatgccagtc aacctttgct
    15721 gctgttgtat tacgctctgt ttcccataca gacagctcgc tgcgcagcag ctcaatgtca
    15781 gctatacggc gggacaggca ctgccgggtc attacattca gctctatttc ggcgatgtcc
    15841 agccaactgc cgtgctttgg ggtataa
//
