LOCUS       c00036_NZ_JAJC..       13225 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JAJCIA010000041.1 Blautia faecis strain DFI.3.66 LDJIBEFH_41,
            whole genome shotgun sequence.
ACCESSION   c00036_NZ_JAJC..
VERSION     c00036_NZ_JAJC..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 01:13:26
            Original ID  :: NZ_JAJCIA010000041.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13225
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13225
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[135:3225]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      136..3225
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13225
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13225
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(136..864)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 79.6;
                     E-value: 9e-25)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_1"
                     /sec_met_domain="Radical_SAM (E-value: 7e-30, bitscore:
                     95.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKGYVHSLESFGSVDGPGVRYVIFLSGCAMRCQFCHNPDTWNMT
                     DGKEYTTDQLLKTALRFKSYWGDKGGITVSGGEPLLQMDFLTELFRKAKEAGVHTTLDT
                     SGNPYTTKVPWHSKWLELMKYTDLLLLDIKQINEQEHVKLTGQTNTNILAMARELSDMG
                     KPVWIRHVLVPGGSDKDEYLHQLADFIHTLKNVERVEVLPYHTLGIFKWEKLGIPYPLE
                     GVKPPTQERIDNARRILGAI"
     CDS             complement(970..3225)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_2"
                     /sec_met_domain="Gly_radical (E-value: 1.9e-41, bitscore:
                     131.8, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 1.8e-267, bitscore:
                     879.3, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDFAQWEGFEGNRWKEQINVRDFIRHNYTPYDGDDSFLEGPTEA
                     TDKLWGKLQELQKAERANNGVLDMETKVVTGLTAYGPGYIAEDLKNLEKVVGLQTDKPL
                     KRAFMPYGGIKMAEQACEMYGYKVDPQIHDMFTKYEFKTHNQGVFDIYTPEMKRARHSH
                     ILTGLPDTYGRGRIVGDYRRVALYGIDALIAGKEKDFADSDRQGMRRYDFQLREEIADQ
                     IRALKGMKEMAKVYGYDISEPAKNAHEAFQWLYFGYLAAIKTQNGAAMSVGRISTFLDI
                     YIERDLKNGVITEKEAQELVDHMVMKFRMVKFARIESYNQLFSGDPVWATLEVAGIGVD
                     GRHMVTKNDYRFLHTLEDMGPAPEPNLTVLYSSKLPENFKKYAANISVTTSSIQYENDD
                     VMRPVWGDDYSICCCVSATETGKEMQFFGARANLAKCLLYAINGGVDEKLKTQVGPEYK
                     PITSEYLDYDEVMQKYDQMMDWLAHLYVGTLNMIHYMHDKYYYEAAEMALIDTKVERSF
                     ATGIAGFSHVVDSLSAIKYAKVKAIRDEDGITTDFQVEGDFPRYGNDDDRADEIARNLL
                     STFMDKLKHIHTYRDSKPTTSILTITSNVVYGKATGALPDGRKAGEPLAPGANPSYGAE
                     QNGLLASLNSVAKLDYEDALDGISNTQTINPEALGHSDEERTDNLVHVLDGYFNQGAHH
                     LNVNVFGKEKLIDAMEHPEKEEYANFTIRVSGYAVKFIDLTREQQLDVIARTCHDRM"
     CDS             3526..3702
                     /locus_tag="ctg36_3"
                     /transl_table=11
                     /translation="MNFREALDGLICIAMFNAIAERVAVNEVDNNLYSFLLAKNLSICF
                     TIILSYVILFLQH"
     CDS             3719..5110
                     /locus_tag="ctg36_4"
                     /transl_table=11
                     /translation="MEKKSNHFSGQLGFVLAAAGSAVGVGNLWRFPYLAAKDGGGLFLI
                     IYLILVLTFGFALLTSDIAIGRHTQKSAIGAYTQMRPRWKFLGILTFLVPVLIMTYYAV
                     IGGWITKYAVVYITGQAQAAASDDYFTAFITSSTSPVIFALLFMGVTAFIVYNGVEKGI
                     EKVSKWMMPVLLVLVVVIAVYSLTISHTDASGQLRTGLQGFLYYLTPDLEGLTVQRFLQ
                     ILLDAMSQLFFSLSVSMGIMITYGSYVKPEVNLNKAINQIEIFDTGVAFLAGAMIIPAV
                     YVFSGTEGMGAGPSLMFISLPKVFSAMGKAGTFVGILFFVTAIFATLSSCISVLESITA
                     NCMEIFHTSRKKTVLVLSVIYLAASAVIALGYSIFYVEVKLPNGSVGQLLDIMDYISNS
                     VMMPFIALLSTILIGWVVTPDYVISEMERSGDKFRRKKLYRVMIRFVAPVMMFILFLQS
                     TGILS"
     CDS             complement(5268..5957)
                     /locus_tag="ctg36_5"
                     /transl_table=11
                     /translation="MDHHKRVQTSEAFINSAFLAVSGGFQDAYTYFTRDGVFSNAQTGN
                     VVLMSERFMNGEVKAGLHYLIPLTAFFLGVLLAERIQEKFRYARRLHWRQGILLVEIIL
                     LFLVGFIPGNLNVLATTLVSFSCALQVQTFRKVEGNAYASTMCIGNLRSGTAALSAYMR
                     ERKPRLLRQALCYFAIIFLFAIGAGIGGRLSMAYGERAIWVSSILLLISFLLMFIEEIE
                     EAEHRWQ"
     CDS             complement(6121..6687)
                     /locus_tag="ctg36_6"
                     /transl_table=11
                     /translation="MERRHITLPLTEELAKTLHAGDQVLLTGTIYTSRDAGHKRMCEAL
                     AKGEKIPFDPTDATIYYVGPTPAKPGQVIGSAGPTTSGRMDAYAPTMMSVGARGMIGKG
                     ARLLEVVEAMKKYHGVYFGAIGGAGALLAKCIKKAELIAYEDLGAEALRKLYVEDMPLV
                     VIIDSEGNNLYEEGRKEYLEAHKEN"
     CDS             complement(6690..7532)
                     /locus_tag="ctg36_7"
                     /transl_table=11
                     /translation="MREVEVSRLTDVIEKLCIEANEHLPEDVKCAIKTCRACEDGEIAK
                     GILDNIIENFDIADNENVPICQDTGMACVFLEIGQDVHFVGGDLTDAINEGVRRGYTNG
                     YLRKSVVKDPVRRGNTGDNTPAMIYTEIVPGDKVKITVGPKGFGSENMSMIRMFKPSAG
                     LQGIKDFILEVVETAGPNPCPPMVVGVGIGGTFDKCALLAKKALMRPLDSHNPDPYYAE
                     LEDEMLEKVNKLGIGPQGFGGKTTAIGLNIETMPTHIAGMPCAVNINCHVTRHKTEVI"
     CDS             complement(7572..9185)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 218.3; E-value:
                     6.6e-67)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg36_8"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.9e-67, bitscore:
                     218.3, seeds: 62, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYAPYPENMMESIKKVEATRAQRMATEPRRLSADEKDALLKKFHP
                     DYNPDAFAEIKVGPNKGQKAPLELAEMLHSESRLLNEKIDLNKIDYDVDVLVIGGGGAG
                     SSCAIEAHNAGANVMIVTKLRIGDANTMMAEGGIQAADKENDSPVQHYLDCFGGGHFAA
                     KPELVKRLVMEAPDAIKWLNDLGVEFDKEDDGTMITTHGGGTSRKRMHAAKDYSGSEIM
                     RTIRDEVLNLGIPVVEFTSAVELLKDEKGQTAGAVLLNMETGDYSVARAKTVVIATGGA
                     GRMHYQGFPTSNHYGATADGLVLGYRAGASLLYQDSIQYHPTGAIYPSQILGALVTEKV
                     RSVGAQLVNANGEAYIHPLETRDVNASGVIRECEEGRGVEVPGGLKGVWLDTPMIEILG
                     GEGTIEKRIPAMFRMYMNYGVDMRKVPIVIYPTLHYQNGGLEIDGDGFTKEIPNLLVAG
                     EAAGGIHGRNRLMGNSLLDVIVFGRNAGKKAAAKCKEVELGEMNLDHIYAYEKELKAAG
                     AETDKVSPLLLPNYARHEQR"
     CDS             complement(9201..9875)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer2_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg36_9"
                     /sec_met_domain="Fer2_4 (E-value: 1.7e-08, bitscore: 25.3,
                     seeds: 126, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENMVNVYFFGKKYTVPADLTIMTAMEYAGYTLKRGCGCRHGFCG
                     ACATIYRIKGDNELKTCLACQTQVQEGMYVASIPFFPTDKRLYNIEDLQPNQQVMMELY
                     PEIYSCIGCNACTKACTQGLNVMQYIAYAQRGELEKCAEESFDCVSCGCCSVRCPAGIS
                     HPMVGLLARRLTGKYIAPKSEHLEKRVEEIHEGKYDDLIEQIMQKPITDMEELYNNREI
                     EK"
     CDS             complement(10147..11001)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FAD_binding_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg36_10"
                     /sec_met_domain="FAD_binding_6 (E-value: 3.2e-11, bitscore:
                     34.4, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_1 (E-value: 1.3e-21, bitscore:
                     68.2, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSECTCHKNYTLDTLIPQVGVITDIHEETPDVKTFCVTAPDGGKL
                     FEHMPGQCAMVCAPGVSEGMFSITSSPTNKEYQEFSIKKCGELTSYLHSLQVGDEITVR
                     GPYGNHFPVEDKLKGKNLLFIAGGIGLAPLRSVINYVLDNRDDYGTVDILYGSRSADDL
                     VKLKEIQEVWMNAKDVNVYLTIDREQEGWDGHVGFVPTYLKEIGFDTNKVALVCGPPIM
                     IKFVLQGLEELGFTRTQVYTTLELRMKCGIGKCGRCNIGSKYVCKDGPVFRMDEIDQLP
                     DEY"
     CDS             complement(11001..12062)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg36_11"
                     /sec_met_domain="Fer4_8 (E-value: 1.5e-09, bitscore: 29.1,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 7.9e-05, bitscore: 14.1,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYKIEKENLEALFRKIAESQDLILPIKKAGQTNFGLWNEGEEADL
                     ETLKTVKSGKDAFFPQSETLYTCVRDGKKLTVEPEELRSRPFVVFGMKACDVKGVAVLD
                     KVFLADPVDTFYAARRDHGTIVALACHEPEESCFCKVFGTDAADPEADADVKGIADVAA
                     WMVEGSLYWKALTEKGEALTEAVKELLIPADDDQVKVDAEKEAIRAIVEKLPYTHLSLE
                     GWDGNATDEKFNSPVWETLYKPCLACGTCTFVCPTCQCYDIKDYDTGHGVKRYRCWDSC
                     MYSDFTMMAHGNNRTSQMQRFRQRFMHKLVYFPANNDGMYSCVGCGRCVEKCPSSLNIV
                     KVIKAFEKHGGEK"
     CDS             complement(12066..13040)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg36_12"
                     /sec_met_domain="Fer4_8 (E-value: 4.2e-11, bitscore: 34.1,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00014, bitscore: 13.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQELIARAKELLADGTVTRVLGWKAGDLPYNPEAAYFETAESLDE
                     FVYNGFCGQNLSKMMIEASKLEGKTLVCLKPCDTYSFNQLIKEHRVDREKAYIIGVGCK
                     GKLDVEKLRKMGIKGIQSISGAELTDDCEELNISTIYGDKTVAYKDAMLERCHVCKGKE
                     HMIYDEIIGESKDTKDADRFAEVEKIEKMSPEERFAFFQKELSKCIRCNACRNACPACS
                     CRKCVFDSTKFDSAQKANVDSFEEKMFHIIRAFHVAGRCTDCGECSRVCPQGIPLHLFN
                     RKFIKDIDTFYGEYQAGADAESKGPLTSFTFDDVEPGVVAERG"
ORIGIN
        1 caccattgtc cgaatgcgtc cgccttgaac aactttcaac acactaaata gcaacttaaa
       61 agaggccatt gcgaactcat ttccagtccg caacggcctc cccttaagga gttttattta
      121 ctttctttca cgctcttaaa tcgccccaag aatccgtctg gcattatcaa tcctctcctg
      181 cgttggaggt ttcacgccct ccagcggata aggaatcccc agcttttccc atttaaaaat
      241 gccaagagta tgatacggaa gaacttccac gcgctcaacg tttttcagtg tatggataaa
      301 atccgccagc tggtgcagat actcatcctt gtcactgccc cccggtacta acacatgccg
      361 gatccaaaca ggcttaccca tatccgaaag ctcacgggcc atggcaagaa tattcgtatt
      421 ggtctgcccg gtaagcttca catgctcctg ctcattgatc tgcttgatat ccagaagcag
      481 aagatctgta tacttcatca gctccagcca cttagaatgc cacggcacct tagtcgtata
      541 aggatttccg ctggtatcca aagtagtatg gactcccgct tcctttgcct tacggaaaag
      601 ctctgtgaga aaatccatct gcaaaagtgg ttccccgccg ctcaccgtga taccaccctt
      661 atctccccag taagacttaa accgaagtgc tgtcttcaaa agctgatccg tagtgtactc
      721 ttttccatct gtcatattcc aggtatccgg attatggcag aactggcaac gcatagcaca
      781 gccagaaaga aaaatcacat atctcactcc aggtccgtcc acagacccga agctctccag
      841 agaatgaaca tagcctttta acatttctaa ttcctttgca ttcatattta taaaaaggac
      901 atgcaacctc taacatatat tgtattgcat gcccttttgt ttcgccgata ctattttaaa
      961 atatcagact tacattctgt cgtggcaggt tctggcaata acatccaact gctgctctct
     1021 tgtcagatcg ataaacttaa ctgcataacc ggaaacacgg atagtgaagt ttgcatactc
     1081 ctctttttcc ggatgctcca tagcatcgat cagtttctct ttgccaaata catttacgtt
     1141 caggtgatgt gcaccctggt tgaaatatcc gtccagtaca tgtaccagat tatctgtacg
     1201 ctcttcatca ctatgtccaa gagcttccgg attaatggtc tgtgtattgg aaattccatc
     1261 cagtgcatcc tcatagtcaa gctttgcaac agagttcagg gaagcaagaa gtccgttctg
     1321 ctctgctccg taagatgggt ttgctccagg tgccagaggc tctccagcct ttcttccatc
     1381 cggaagagct ccggtagctt taccataaac aacgttagaa gtaatggtaa gaatagaagt
     1441 ggttggcttg gaatcacggt aggtatggat gtgtttcagt ttatccatga aggtggaaag
     1501 cagatttctt gcaatctcat ctgctctgtc atcatcatta ccatagcgtg ggaaatcacc
     1561 ctcaacctgg aaatcagtgg taattccatc ctcatcacgg atagctttta ccttcgcata
     1621 cttaatagca gacagagaat ctactacatg tgaaaatcca gcaatacctg ttgcaaaaga
     1681 acgctcaacc ttggtatcga taagcgccat ctcagctgcc tcatagtaat atttatcatg
     1741 catatagtgg atcatgttca gagttcctac atacagatga gccagccagt ccatcatctg
     1801 gtcatatttc tgcataacct catcataatc aagatactcg gaagtgatcg gcttgtactc
     1861 cggtcctacc tgagtcttta acttctcatc cacaccaccg ttgatcgcat aaaggaggca
     1921 tttcgcaagg tttgcacgag ctccaaagaa ctgcatttcc ttaccagtct cagtagcaga
     1981 tacacagcag cagatggaat aatcatcgcc ccataccgga cgcataacat catcgttctc
     2041 atactggata gaacttgttg taacagaaat attagcagca tatttcttga agttttccgg
     2101 cagcttggaa gaataaagaa cagtaaggtt tggctccgga gccggtccca tatcctcaag
     2161 agtatgaagg aaacgatagt cattcttggt aaccatgtgg cgtccgtcaa caccaatacc
     2221 tgcaacctca agagttgccc ataccgggtc accggagaac agctggttgt aggactcaat
     2281 tcttgcaaat ttaaccatac ggaatttcat taccatgtgg tcaacaagct cctgtgcctc
     2341 tttctcagtg atcacgccat tcttaaggtc tctttcaata tagatatcaa ggaatgtgga
     2401 gatacgtcca acactcattg cagcaccatt ctgggtctta attgctgcaa gatatccaaa
     2461 gtacagccac tggaatgcct catgagcatt ctttgcaggc tctgaaatat cataaccata
     2521 gacctttgcc atctctttca ttcctttaag agcgcggatc tgatctgcga tttcctcacg
     2581 aagctggaaa tcataacgtc tcataccctg gcggtcgctg tctgcaaagt ctttctcctt
     2641 gcctgcgatc agagcgtcaa taccgtacag agccacacgt ctgtaatcgc caactatacg
     2701 tccacgtcca taagtatccg gaagtccggt aaggatgtgg ctgtgacgtg ctcttttcat
     2761 ttctggtgta taaatgtcaa aaacgccctg gttatgtgtt ttgaactcat attttgtaaa
     2821 catatcgtgg atctgaggat ctaccttgta gccgtacatt tcgcatgcct gctcagccat
     2881 tttgattccg ccgtatggca taaatgcacg tttcagaggc ttgtctgtct gaagtcctac
     2941 aaccttctca agattcttta ggtcttcagc aatatatcct ggtccgtatg cggtcaggcc
     3001 tgtgacaacc tttgtctcca tgtcaagcac accattgttg gcacgctctg ctttctgcag
     3061 ctcctgcagc tttccccaca gtttgtcagt agcctcggtc gggccttcca ggaaagaatc
     3121 gtctccgtca taaggggtat aattgtgacg gataaaatca cgaacgttaa tctgttcttt
     3181 ccaacgattt ccttcgaagc cttcccactg tgcaaaatct ttcattcttg tacctctttc
     3241 tttattttat agttctccgc gtatattgaa gaattgttat tagtttaacg attgtagtat
     3301 acgagattgt tatttcttag tcaatcggtt tggggaatgc ttttaataaa gtacaattta
     3361 tctggtaaaa aatggatttc cctatatata agtcctatat tatgtacttt aattcatttt
     3421 tccatttgta agccccattt tcactgtagt aaatacagag aaatattctc gatatacttt
     3481 gttaaatttt atcaacttaa ttgaaggggg gctatcgctt aacgaatgaa ttttcgtgaa
     3541 gctctcgatg gtcttatctg tatcgccatg ttcaatgcca tcgcggagcg tgttgctgtg
     3601 aacgaagtgg acaataactt atactccttt ctgcttgcta aaaatttaag tatttgtttt
     3661 actattatct tgtcatatgt tatcctattc ttacaacatt aagggggaaa caaatgtaat
     3721 ggaaaagaaa tcaaaccatt tttcaggaca gcttggtttt gtcctggctg cagccggaag
     3781 tgctgtagga gtgggaaatt tgtggagatt cccatacctt gccgcaaagg acggaggcgg
     3841 cttattttta attatctacc taattctggt actaaccttc ggatttgccc ttctcacctc
     3901 tgatattgcg atcggacggc atacacagaa gagtgccatc ggagcctata cccagatgcg
     3961 tcccagatgg aagttcctgg gaatccttac cttccttgta ccagtgctta ttatgaccta
     4021 ttacgcggtc atcggcggat ggatcaccaa atatgcagtg gtatacataa ccggtcaggc
     4081 acaggcagct gcctcagatg actattttac agcctttatc acctcttcca cttcaccggt
     4141 gatcttcgca ctgcttttca tgggtgttac tgctttcatt gtatacaatg gcgtggaaaa
     4201 ggggattgaa aaagtatcca aatggatgat gccggtcctg ctagttctgg tcgtagtgat
     4261 tgcagtgtat tctcttacga tttcacatac ggatgcttcc ggtcagcttc gcaccggctt
     4321 acagggattt ctttactacc tgacgcctga ccttgaagga ctgactgtgc agcgttttct
     4381 gcagattctg ctggatgcca tgagccagct gttcttttca ctcagtgtat ccatgggaat
     4441 tatgatcacc tacggctcct atgtaaaacc tgaagtgaac ctaaacaaag cgatcaatca
     4501 gattgaaatt tttgacacag gtgttgcctt tcttgcaggt gccatgatca tcccggctgt
     4561 atatgtgttt tccggcactg agggaatggg tgccggacca agcctgatgt ttatttccct
     4621 gccaaaggta ttttctgcaa tgggaaaagc tggtaccttc gtaggaatcc tgtttttcgt
     4681 aactgctatt tttgcaacct tgtcttcctg tatttccgta ctggaatcta ttactgcaaa
     4741 ctgcatggaa atttttcata ccagccgtaa aaaaacagtt cttgttttat ctgtgatcta
     4801 ccttgcagct tccgcagtta tcgctttggg atacagtatt ttctatgtgg aagtgaagct
     4861 tccgaacggt tctgtaggac agcttcttga tattatggat tacatcagca acagtgttat
     4921 gatgccgttt attgcactgc tttccacgat tctcatcggc tgggtcgtaa cgccggatta
     4981 tgtgattagc gaaatggaaa gaagcgggga taagttccgt aggaaaaaat tgtaccgcgt
     5041 catgatccgc tttgttgcgc cggttatgat gtttattctg tttttacaat ctacagggat
     5101 tttatcttaa actgcaaagc acgtttgaga aaggcttttt gcaagatgtg cctcacaatt
     5161 ttggaaagct tatattgcgc aaaaaacatc cagcctgcca tcgttgtatg gagactggat
     5221 gtttttataa tttgtaattg tttagatact gaagctttat tagtttctca ctgccagcgg
     5281 tgttctgcct cttcgatttc ctcaataaac attaaaagga agctgatgag aagcaggatg
     5341 ctggataccc agatggctct ttcgccgtaa gccattgaaa gtctgccgcc aattcctgcg
     5401 ccaatggcaa acaggaaaat aatggcgaag tagcataagg cctgacgaag caggcgtggc
     5461 tttctttcac gcatgtaagc ggaaagagcg gcagtgccgc ttctcagatt tccgatacac
     5521 atggtgctgg cataggcatt tccttcaacc tttcggaagg tctgcacctg aagggcgcag
     5581 gagaaggata ccagggtggt ggcaagcacg ttcaggttcc ctgggatgaa gccaaccaga
     5641 aacagcagga tgatctctac cagaaggatt ccctggcgcc agtgaaggcg tctggcatag
     5701 cggaattttt cctgaatgcg ttccgctaac agaactccaa gaaagaatgc ggtcagggga
     5761 atgagataat gcaatcctgc tttcacttcg ccgttcataa accgctcact catcagtacc
     5821 acgtttccgg tctgggcgtt ggagaaaacg ccatcgcggg taaaataggt ataggcatcc
     5881 tgaaatcctc ctgacactgc aaggaatgca ctgtttatga atgcttctga ggtctgtacc
     5941 cttttatgat ggtccataat aagctccttc tttcgtcttt tgtctttcgt atacatatct
     6001 tcagattata gaataaataa tgctttctgt aaacatctat tttgatatgt ggagtatata
     6061 tatcttatat gcctggagcg tatttgaaaa agactttctg caggatttcc gtcacaatta
     6121 ttagttttct ttatgtgctt ccagatactc ttttcttccc tcttcataaa gattgttgcc
     6181 ttcgctgtca ataatgacta caaggggcat atcttctacg taaagcttac ggagagcttc
     6241 tgcacccaga tcctcgtatg cgataagctc cgcttttttg atacatttgg caagaagggc
     6301 gccggcaccg ccgatggctc cgaagtaaac accgtgatat tttttcatgg cttctactac
     6361 ttcaagcaga cgcgctcctt tgccgatcat tccgcgggct cctacagaca tcatggttgg
     6421 tgcgtaggca tccatacggc cgctggtagt tggtccggca gatccgatga cctgacctgg
     6481 ttttgcagga gttggaccta cataataaat agttgcatct gttggatcaa aaggaatctt
     6541 ttcgcctttt gcaagagcct cacacatacg cttgtgacct gcgtcacggg atgtgtagat
     6601 ggttccggta aggagaacct gatctcctgc gtgaagggtt tttgccagtt cttccgtcag
     6661 aggcagtgta atatgtcttc tttccatgat cagatcacct ccgttttgtg gcgggtaacg
     6721 tggcagttga tgttgactgc acatggcatt cccgcaatgt gagtaggcat tgtctcaata
     6781 ttcaggccga tggctgtggt ctttcctcca aagccctgtg gtccgattcc aagcttgttt
     6841 actttctcca gcatttcgtc ttccagctct gcatagtatg gatccggatt gtgggaatcc
     6901 agaggacgca tcagtgcctt ctttgcaaga agagcacatt tgtcaaaagt tccgccgatt
     6961 ccaacaccta caaccatagg agggcatggg ttcggacctg ctgtctcaac gacttccaga
     7021 atgaaatcct tgattccctg aagtcctgca gatggcttga acatacggat catactcatg
     7081 ttctcacttc cgaagccctt cgggccaact gtgatcttta ctttatcacc aggaacgatt
     7141 tctgtataga tcatagccgg tgtattgtct cctgtatttc cacggcgtac aggatctttt
     7201 acaacagatt tgcgaagata tccgtttgta tatccgcggc gtacaccttc attgatggca
     7261 tcagtaagat ctccgccaac aaagtgcaca tcctgtccaa tttcaaggaa cacacatgcc
     7321 attcctgtat cctggcagat cggtacattt tcgttatctg caatatcaaa attctcgata
     7381 atattgtcaa gaataccctt ggcaatctct ccgtcttcgc atgcgcggca tgttttgata
     7441 gcgcatttta cgtcttccgg aagatgttcg tttgcttcga tacagagttt ttcgatgacg
     7501 tctgtaagtc tgcttacttc tacttcacgc attttggtaa gctcccttct tttataatat
     7561 ttatttcatt tttatctctg ctcgtggcgg gcgtagtttg gaagcagtaa tggagatact
     7621 ttatcggtct ctgctcctgc tgcttttaac tctttctcat atgcgtaaat atgatccagg
     7681 ttcatttctc caagctctac ctctttgcat tttgcagcag cctttttacc ggcatttctt
     7741 ccgaatacga ttacgtccag aagagagttg cccatcagtc tgtttcttcc gtggattccg
     7801 cctgcagctt ctcctgcaac cagaaggttc gggatttctt ttgtaaatcc gtctccatca
     7861 atttccagac caccgttctg gtagtgaaga gtaggataga tcacgatcgg cacttttctc
     7921 atgtcaacgc cgtagttcat gtacatacgg aacattgccg gaattctctt ctcaatagtt
     7981 ccctcgcctc caaggatctc gatcatcgga gtatccagcc atacaccttt caatccgcca
     8041 ggaacttcta cgccacggcc ttcctcacac tcacggataa caccggaagc attgacatca
     8101 cgggtttcca aagggtgaat ataggcttct ccgtttgcat ttacaagctg tgcgccaaca
     8161 gaacggacct tctctgttac cagcgcgcca aggatctgtg acggataaat ggcaccagtc
     8221 ggatggtact ggatggaatc ctgataaaga agggaagcac ctgctctgta accaagtaca
     8281 agaccatctg cggttgcgcc gtagtggtta gaggtaggga atccctgata gtgcattctt
     8341 cctgctccgc cggttgcaat gacaacggtt tttgctcttg caacggagta atcgccggtt
     8401 tccatgttaa gaagaacagc acctgcagtc tgtccttttt catctttcag aagttctaca
     8461 gcagaagtaa attctactac cggaatgcca aggttcagaa cctcgtcacg gatagtacgc
     8521 atgatttcag atccggaata atcctttgca gcatgcattc tctttctgga ggttccgcca
     8581 ccgtgtgtgg tgatcatggt tccatcgtct tctttatcga actcaacgcc aagatcattc
     8641 agccatttaa ttgcatccgg agcttccatt acaagtctct ttaccagctc tggttttgca
     8701 gcaaaatgtc cgccgccgaa gcagtccaga taatgctgta caggagaatc gttttctttg
     8761 tcagctgcct ggattccgcc ttctgccatc atggtgttgg catcaccgat acgaagcttg
     8821 gtcacgatca ttacgttggc acctgcattg tgtgcttcga tggcacagga tgagcctgca
     8881 ccgccgccgc cgattacaag tacatctaca tcataatcga ttttgttaag gtcaattttt
     8941 tcattcagaa gacggctttc ggagtgaagc atttctgcca gctccagtgg tgccttctgt
     9001 cctttgtttg gtcctacttt gatttctgca aatgcatccg ggttatagtc tggatggaat
     9061 ttcttaagaa gagcatcttt ctcatcagcg ctcagacgtc ttggctctgt tgccatacgc
     9121 tgtgctcttg tagcctctac ctttttgatg gattccatca tattttctgg atatggtgcg
     9181 tacatgtttt tatgccctcc ttatttctca atttctctgt tgttgtaaag ttcttccatg
     9241 tctgtgatcg gtttctgcat gatctgctcg atcaggtcat catatttacc ttcatgaatc
     9301 tcttctacac gtttttcaag atgctcactc ttaggagcaa tgtattttcc tgtgagacgt
     9361 cttgcaagaa ggcctaccat cggatgggag atacctgccg gacatcttac ggaacagcat
     9421 ccgcagctta cgcagtcaaa ggattcttct gcgcatttct caagctcacc tctctgcgca
     9481 tatgcgatgt actgcattac atttaagccc tgggtacatg cttttgtaca cgcgttacag
     9541 ccgatgcagc tgtaaatttc cgggtagagc tccatcatga cctgctggtt tggctgaagg
     9601 tcttcgatgt tgtagagtct cttgtctgta gggaagaacg ggatgcttgc tacatacatg
     9661 ccttcctgta cctgtgtctg acaggcaaga caggttttca gttcgttgtc gcctttgatt
     9721 ctgtagattg tggcgcaggc gccgcagaag ccgtgacggc agccgcagcc gcgttttaaa
     9781 gtgtatccgg cgtattccat ggccgtcata atggtcaggt cagctggtac ggtgtatttt
     9841 ttaccgaaga aatatacgtt taccatattt tccatgttgt ggggtccttt cttctactta
     9901 ttcaacccgt acgacttgtg aaatgggtat cccgcatgtg cccgtcgcaa cgctctgctg
     9961 aactaatcgc taactgcgac taaggagttc aggagagcct tcactcctaa gtcttcgtaa
    10021 gcgctggatt tcagcgccgc taaaaccgct cctgaaatgg gcatcttagc gagataccca
    10081 ttccccaagt ctgtgtactg gcaataactg attcatttat tcgaaagttt cttaagatta
    10141 aaaagtttag tactcgtcag gtaattgatc gatctcgtcc attctaaaaa ccggaccatc
    10201 tttacatacg tacttagatc cgatattaca acgtccgcat ttaccaatac cgcacttcat
    10261 acgaagctcc agtgttgtat aaacctgagt tcttgtaaat ccaagctcct caaggccctg
    10321 aagtacgaat ttgatcatga tcggcggtcc acagactaat gcgactttgt tggtatcaaa
    10381 gccgatttct tttaaataag tcggtacgaa acctacatgt ccgtcccagc cttcctgctc
    10441 acggtcgatg gtcagataga cgtttacgtc ttttgcattc atccacactt cctggatctc
    10501 ttttaatttt acaagatcgt ctgcggaacg ggaaccgtag aggatgtcta cagtgccgta
    10561 gtcatcacgg ttgtccagca cgtaattgat cacggaacga agtggtgcaa gaccgatacc
    10621 tccggcgata aagagaagat ttttgccttt caacttatcc tctaccggga aatggtttcc
    10681 gtatggtcca cggactgtga tctcatctcc cacctgaagg ctgtgaagat aagaggtcag
    10741 ctcaccacat ttcttaatac tgaattcctg atactcttta tttgtaggag aggaagtaat
    10801 ggaaaacata ccttcgctta caccaggagc acaaaccatg gcacactgtc caggcatatg
    10861 ttcaaaaagc tttcctccat ccggtgctgt tacacagaat gtttttacat ccggagtctc
    10921 ctcatgaata tctgtgatca cgccaacctg cgggatcaga gtatccagag tataattttt
    10981 atgacaggta cactcgctca ttacttttca cctccatgct tttcaaaagc cttgatcacc
    11041 tttacgatat ttaaagatga cggacatttt tccacgcagc ggccacagcc tacacaagag
    11101 tacataccgt cgttattagc agggaaatat acaagcttgt gcataaatct ctgacggaat
    11161 ctctgcatct ggctggtacg gttatttccg tgagccatca ttgtgaaatc ggaatacata
    11221 caggaatccc agcagcggta acgctttaca ccgtgtcctg tgtcgtaatc cttaatgtcg
    11281 tagcactggc aggtcggaca tacaaaggta caggttccgc atgccagaca tggtttatat
    11341 aaggtctccc agacaggaga attaaacttc tcatctgtgg cgtttccatc ccagccttcc
    11401 agggaaagat gggtgtatgg aagtttttcc acaatggctc tgattgcctc tttttccgca
    11461 tccactttta cctgatcgtc gtcggccggg ataagaagtt cttttactgc ttctgtaaga
    11521 gcctctcctt tttcagtaag agctttccag taaaggcttc cctccaccat ccaggctgct
    11581 acatcggcaa tgccttttac gtcggcatct gcttccggat ctgctgcatc tgttccaaaa
    11641 accttacaga aacaggattc ctccggctca tgacaagcca gggcaacgat agttccatgg
    11701 tctcttcttg ctgcatagaa agtatcaaca ggatcagcaa gaaaaacctt atccagaact
    11761 gcaacccctt ttacatcgca ggccttcatg ccaaatacaa cgaacggacg gcttctcagc
    11821 tcttccggct ctacggtcag cttctttcca tcacgaacac aggtgtaaag tgtttcgctc
    11881 tgtgggaaaa aggcatcttt gccggatttt acggttttca atgtctcaag gtctgcctct
    11941 tctccttcat tccaaaggcc gaagttggtc tgtcctgcct ttttgatcgg aaggatcaga
    12001 tcctggcttt ctgcgatttt ccggaataat gcttccagat tttctttttc aatcttatac
    12061 atacattatc ccctttctgc cactacacct ggctctacat catcaaatgt aaagctggtc
    12121 agcgggcctt tagactctgc atcagctcct gcctgatatt caccgtagaa ggtatcaata
    12181 tctttgatga acttacggtt aaacagatga agcggaatcc cctgcgggca gacacggctg
    12241 cactcaccgc agtctgtaca tcttcctgca acgtggaatg cacggataat gtggaacatt
    12301 ttttcttcaa aggaatccac atttgccttc tgtgcactgt caaacttggt gctgtcgaac
    12361 acacatttac ggcagctgca ggccggacat gcattacggc atgcattaca gcggatacat
    12421 ttactaagct ccttctggaa aaatgcgaag cgctcttccg ggctcatctt ctcaattttc
    12481 tccacctctg caaaacggtc tgcatccttt gtatccttgg attcgccgat gatctcgtcg
    12541 tagatcatgt gctcttttcc tttgcataca tggcagcgct ccagcattgc atccttgtaa
    12601 gcgactgttt tgtcaccata gattgtggaa atgttaagtt cttcacaatc atcggtaagc
    12661 tcagcgccgg aaatgctctg gattcccttg atgcccattt tacgaagctt ctccacatcc
    12721 agcttgcctt tacagccaac accgataatg taggcttttt cacggtctac acggtgctcc
    12781 ttgatcagct ggttgaagct gtaggtatca caaggcttca gacagacaag agtttttccc
    12841 tctaatttgg aagcctcgat catcatttta cttaaattct gtccgcagaa accattgtag
    12901 acaaattcgt ccaggctttc tgcagtttcg aaatatgctg cttccggatt gtaaggcagg
    12961 tctccggctt tccagccaag aacacgtgtt acggttccat cagccagcag ttcttttgca
    13021 cgagcgatca gttcctgcat cttaaatcct ccaatctgac gtttttaccc agagaatgga
    13081 ttttttccac aaattcattc atggtctggg agaattttac accttctgcg gcagataccc
    13141 actcaacacg ggtacggcca ttttccacac caatgaagtc cagcatggag aaaagaagtg
    13201 tcatacgtct tctcgcataa tagtt
//
