LOCUS       NZ_CP028101.1          24694 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP028101.1 Fusobacterium nucleatum subsp. nucleatum ATCC 25586
            chromosome, complete genome.
ACCESSION   NZ_CP028101
VERSION     NZ_CP028101.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:57:10
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1825093
            Orig. end    :: 1849787
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24694
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[1835093:1839787]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [Aldedh, HAD, HAD_2, IDH, Ldh_1_C, Ldh_1_N,
                     Succ_CoA_lig]) and not (PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene or
                     Gly_radical or Gly_430_pcre or Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_lactate_related"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14694
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [Aldedh, HAD, HAD_2, IDH, Ldh_1_C, Ldh_1_N,
                     Succ_CoA_lig]) and not (PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene or
                     Gly_radical or Gly_430_pcre or Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_lactate_related"
                     /protocluster_number="1"
     cand_cluster    1..24694
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [Aldedh, HAD, HAD_2, IDH, Ldh_1_C, Ldh_1_N,
                     Succ_CoA_lig]) and not (PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene or
                     Gly_radical or Gly_430_pcre or Gly_8-9_TMA))"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="chemical_hybrid"
                     /product="OD_lactate_related"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="gutsmash"
     region          1..24694
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="OD_lactate_related"
                     /product="PFOR_II_pathway"
                     /region_number="8"
                     /rules="(minimum(1, [PFOR_II, POR, POR_N]) and minimum(2,
                     [Aldedh, HAD, HAD_2, IDH, Ldh_1_C, Ldh_1_N, Succ_CoA_lig])
                     and not (PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene or
                     Gly_radical or Gly_430_pcre or Gly_8-9_TMA))"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             1650..2444
                     /locus_tag="ctg1_1698"
                     /transl_table=11
                     /translation="MAEKTQRIGIFDSGLGGTTVLKELINSLPNEDYIYYGDNGNFPYG
                     SGKTKNELQKLTERILDFFVKNNCKLVIVACNTASTAAIDYLREKFSLPIIGIIEAGVK
                     IASKNTKNKNIAVISTKFTAESHGYKNKAKMLDSELNVKEIACIEFAQMIETGWDTFDN
                     RKELLNKYLSEIPKNADTLVLGCTHYPLIREDIEKNIKIKVVDPAVEIVERTIQTLTSL
                     NLLNDKKERGRIIFFVTGETYHFKPTAEKFLGKEIEIYRIPK"
     protocluster    1650..24189
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[1836220:1839787](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="2"
                     /tool="gutsmash"
     proto_core      complement(11128..14694)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="2"
     CDS             2632..3255
                     /locus_tag="ctg1_1699"
                     /transl_table=11
                     /translation="LRVKCFHLGAYGTNCFLAYDENNIAYFFDCGGRNLEKVYEFISEH
                     NLDLKYIVLTHGHGDHIEGLNDLASHYPEAKVYIGEEDKDFLYNSELSLSDAIFGEFFK
                     FKGEIHTVKESDMVGDFKVIDTPGHTIGSKSFYYEKDKILISGDTLFRRSYGRYDLPTG
                     SLEMLCHSLKKLSKLPDETVVYNGHTDNTTIGEERRFLERVGIL"
     CDS             3278..4201
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1700"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.3e-30, bitscore:
                     103.6, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKIYDVIIVGAGPAGLTAGIYAGRGNLSTLILEKEGIGSMIMTH
                     QIDNYPGSHIGASGKEIYDTMKKQALDFGCEIKPATVLGFDPYDEIKVVKTDAGNFKTK
                     YIIIATGLGKIGAKKVKGENKFLGAGVSYCATCDGAFTKGRVVSLVGKGDEIIEEALFL
                     TRYAKEVNIFLTSDDLDCNEELKEAILSKENVKITKKVKLLEIKGEEFVTELELEIAGN
                     KETISTDFVFLYLGTKNNIELYGEFVNLSEAGYIITDETMKTRTDKMYAIGDIREKDVR
                     QVATATNDGVIATTFILKEILKSKKK"
     CDS             4225..5172
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ROK"
                     /gene_functions="other (smcogs) SMCOG1034:Repressor, ORF,
                     Kinase (Score: 239.1; E-value: 2.4e-73)"
                     /gene_kind="other"
                     /locus_tag="ctg1_1701"
                     /sec_met_domain="ROK (E-value: 7.9e-72, bitscore: 239.1,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHYIGIDLGGTNTKIGVVDSEGNLINSKIIKTHSHQNVDKTLER
                     IWETAKKLILEKEIPLFSVVGIGIGIPGPVKNQSTVGFFANFDWEKNLNLKEKMEKLSG
                     IETRIENDANIIAQGEAIFGAAKGKKSSITIAIGTGIGGGIFYNGNLISGMSGVGGEIG
                     HMKVVKDGKTCGCGQNGCFEAYASASSLVKEAKERLKLNEDNLLFKEINGDLDELEAKN
                     IFDAARKGDQFSKDLIEYESDYLALGIGNLLNIINPECIVISGGISLAGDEILLPIKEK
                     LKKYTMPPALENLEIKIGTLGNEAGVKGAVALFI"
     CDS             5369..6394
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1702"
                     /sec_met_domain="Peripla_BP_1 (E-value: 2.1e-08, bitscore:
                     30.8, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKFGMLLGSIILASALVACGEKKEEAKTDAPATEKLSIGLTAYK
                     FDDNFIALFRKAFEAEAAAKADIVAVTAIDSQNSVATEKEQIEAVLEKGVKAFAINLVD
                     ASAADGIINLLKEKDVPVVFYNRKPSDEAIASYDKLFYVGIDPNAQGIAQGELIEKLWK
                     ENPDLDLNKDGVIQYVMLTGEPGHPDAVARTKYSISTLNDHGVKTEELHQDTAMWDTAT
                     AKDKMDAWLSGPNGSKIEVVICNNDGMALGAVESMKAAGKVLPTFGVDALPEALVKIEA
                     GEMAGTVLNDAKGQASATFNMVVNLAQGKEATEGTDLKLDNKIILIPSIGIDKSNVADF
                     K"
     CDS             6484..7986
                     /locus_tag="ctg1_1703"
                     /transl_table=11
                     /translation="MENLKYVLEMENISKEFPGVKALDDVQLKLKPGTVHALMGENGAG
                     KSTLMKCLFGIYEKNSGKILLDGVEVNFKSTKEALENGVSMVHQELNQVLQRNVLDNIW
                     LGRYPMKGFFVDEKKMYNDTINIFKDLDIKVDPRKKVADLPIAERQMIEIAKAVSYKSK
                     VIVMDEPTSSLTEKEVDHLFRIIKKLKESGVGIIYISHKMEEIKMISDEITILRDGKWI
                     STNDVSKISTEQIISMMVGRDLTERFPKKDNKAKEMILEVKNLTALNQPSIQDVSFELY
                     KGEILGIAGLVGSKRTEIVETIFGMRPKKHGEIILNGKTVKNKSPEDAIKNGFALVTEE
                     RRSTGIFSMLDVAFNSVISNLDRYKNKFRLLKNKDIEKDTKWIVDSMRVKTPSYSTKIG
                     SLSGGNQQKVIIGRWLLTEPEVLMLDEPTRGIDVLAKYEIYQLMIDLAKKDKGIIMISS
                     EMPELLGVTDRILVMSNGRVAGIVKTSETNQEEIMELSAKYL"
     CDS             8009..9028
                     /locus_tag="ctg1_1704"
                     /transl_table=11
                     /translation="MIARTNEGKIDYKKIIIESGLYLVLFCMLVAIIIKEPTFLSLRNF
                     KNILTQSSVRTIIALGVAGLIVTQGTDLSAGRQVGLSAVISGTLLQSMTNVNKAFPKLG
                     EFSIFTTILIVVVVGVVIASINGVVVATLNVHPFIATMGTMTIVYGINSLYYDKAGAAP
                     ISGFVEKYSKFAQGYIKIGSYTIPYLIIYAAIATLIMWTLWNKTKFGKNVFAVGGNPEA
                     AKVSGVNVVLTLMGIYALSGAYYAFGGFLEAGRIGSATNNLGFMYEMDAIAACVIGGVS
                     FYGGVGRISGVITGVIILTIINYGLTYTGVSPYWQYIIKGIIIVTAVAFDSIKYAKKK"
     CDS             complement(9072..9980)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 73; E-value: 7.3e-23)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_1705"
                     /sec_met_domain="MFS_1 (E-value: 2.4e-21, bitscore: 73.0,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VQSKESNIKLLLLGRVVSLFGNTIYLIVLPLYILNITQNLKTTGI
                     FFASINLPTIIISPLIGTLIEKFNKKNIILICDFLTSMLYFIPFLYFKNSNSVIFLLIV
                     SLILNIISKFFEIASKVLFSEINTPETLEKYNGLQSFLENAVMIFGPVVGTYLFATFTF
                     NFVLIIISLAYFLSFLQELFIKYEKNTNLSKEKSSFFKDFKEGISYIKSKKIIFNFFIL
                     AMFLNFFIANNDEIINPGILIKKYQISEKLFGFSVACYGLGSVVAGYLSSYIGADVTYI
                     IDNVAIIIIVFLVFKNIERDC"
     CDS             complement(10001..10957)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_lactate_related: Ldh_1_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_lactate_related: Ldh_1_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1706"
                     /sec_met_domain="Ldh_1_C (E-value: 1.1e-25, bitscore: 87.4,
                     seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Ldh_1_N (E-value: 4.5e-26, bitscore: 88.6,
                     seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLQTRKVGIVGIGHVGSHCALSMLLQGVCDEMVLMDIIPEKAKAH
                     AIDCMDTISFLPHRAIIRDGGIQELSKMDVIVISVGSLTKNEQRLEELKGSLEAIKSFV
                     PDVVKAGFNGIFVTITNPVDIVTYFVRELSGFPKNRVIGTGTGLDSARLKRILSEVTNI
                     DSQVIQAYMLGEHGDTQIANFSSATIQGVPFLDYMKTHPEQFKGVELSVLEKQVVRTAW
                     DIISGKNCTEFGIGCTCSNLVKAIFHNERRVLPCSAYLNGEYGHSGFYTGVPAIIGSNG
                     VEEILELPLDERERKGFEDACAVMKKYIEVGKSYKIV"
     CDS             complement(11128..14694)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_lactate_related: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_lactate_related: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_lactate_related: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1707"
                     /sec_met_domain="PFOR_II (E-value: 1.3e-15, bitscore: 54.5,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 5.9e-81, bitscore: 268.5,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 1.2e-31, bitscore: 107.0,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.2e-13, bitscore:
                     48.0, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.8e-10, bitscore: 37.9,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 3.5e-07, bitscore: 26.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.0019, bitscore: 15.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 3.3e-20, bitscore: 68.6,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKKMQTMDGNQAAAYASYAFTEVAGIYPITPSSPMAEYTDEWAA
                     KGMKNIFGVPVKLVEMQSEGGAAGTVHGSLQAGALTTTYTASQGLLLKIPNMYKIAGEL
                     LPGVIHVSARSLSAQALSIFGDHQDIYAARQTGFAMLATNSVQEVMDLAGVAHLSALKS
                     RVPFLHFFDGFRTSHEIQKVEVMDYEDLKKLVDWKALEGFRKRALNPEHPVTRGTAQND
                     DIYFQAREVQNKFYDAVPDIVADYMKEISKITGREYKPFNYYGAPDAERVIIAMGSVCE
                     AAQEVIDYLVEKGEKVGLISVHLFRPFSAKYFFDILPKTAKRISVLDRTKEPGSLGEPL
                     LLDIKALFYNKENAPLIVGGRYGLSSKDTTPAQIKAVFDNLAKDTPKDAFTVGIVDDVT
                     HTSLEVGPAMALADPTTKACLFYGLGADGTVGANKNSIKIIGDKTDLYAQGYFAYDSKK
                     SGGVTRSHLRFGKKPIRSTYLVSRPTFVACSVPAYLNQYDMTSGLKEGGKFLLNCVWTK
                     EEAIANIPNNVKRDLAKNKARLFIINATALAQEIGLGQRTNTIMQAAFFKLAEIIPFEE
                     AQQYMKDYAKKSYAKKGDEIVQLNYNAIDRGANDIIEIEVDPAWANLEVTPLNEPKETT
                     GCAYCQPDTEFVKKIVRPVNAIKGYDLPVSAFLGYEDGTFENGTSAFEKRGVAVDVPIW
                     NVDKCIQCNQCSYVCPHAAIRPFLINEDELKAAPNSFATKKATGKGLDELVYRIQVSAL
                     DCVGCGSCANVCPANALDMRPIAESLETHEDINTNYLYNNVEYRSNLMPLDTVKGSQFS
                     QPLFEFHGACPGCGETPYIKLITQLYGDRMMVANATGCSSIYSGSAPATPYTTNKNGEG
                     PSWGSSLFEDNAEYGFGMHVGVEALRFRIQHTMEENMDKVDEDIATLFKDWIANRQYSV
                     RTREVRDILVPKLEALGTDFAKEILDLKQYLVKKSQWIIGGDGWAYDIGYGGLDHVLAS
                     NEDINVLVMDTEVYSNTGGQASKATPTGSVAKFAAAGKPVKKKDLAAIAMSYGHIYVAQ
                     VSMGANQQQFIKAVKEAEAHQGPSIIIAYSPCINHGIKKGMSKSQTEMKLATECGYWPI
                     FRYNPSLEKIGKNPLQIDSKEPKWEKYEEYLTGEVRYQTLAKSNPEEAKNLFETNKKDA
                     QKRWRQYKRMAALDYSEEKEAE"
     CDS             complement(14786..15982)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetate_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1708"
                     /sec_met_domain="Acetate_kinase (E-value: 1.2e-148,
                     bitscore: 491.9, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKILVINCGSSSLKYQLINPETEEVFAKGLCERIGIDGSKLEYEV
                     VAKDFEKKLETPMPSHKEALELVISHLTDKEIGVIASVDEVDAIGHRVVHGGEEFAQSV
                     LINDAVLKAIEANNDLAPLHNPANLMGIRTCMELMPGKKNVAVFDTAFHQTMKPEAFMY
                     PLPYEDYKELKVRKYGFHGTSHLYVSGIMREIMGNPEHSKIIVCHLGNGASITAVKDGK
                     SVDTSMGLTPLQGLMMGTRCGDIDPAAVLFVKNKRGLTDAQMDDRMNKKSGILGLFGKS
                     SDCRDLENAVVEGDERAILAESVSMHRLRSYIGAYAAIMGGVDAICFTGGIGENSSMTR
                     EKALEGLEFLGVELDKEINSVRKKGNVKLSKDSSKVLIYKIPTNEELVIARDTFRLAK"
     CDS             complement(16033..17037)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTA_PTB"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1709"
                     /sec_met_domain="PTA_PTB (E-value: 5.2e-120, bitscore:
                     397.4, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFLGQVRKKALQANRRIVLPESSDERIIRATSQILKEGLAQVVL
                     VGNQEAIMHSAKAYEVSLSGAKIVDPYNFERLNDYINKLVELRAKKGMTPEEAKKILLN
                     DPTFFGAMLVRMGDADGMVSGSASPTANVLRAAIQVIGTQPGVKTVSSVFIMELSQFKD
                     LFGSILVFGDCSVIPFPTSEQLADIATSAAETAIKIAGINPRVALMTFSTKGSAKHECV
                     DRVIEAGHILRERKVQFRFDAELQADAALVKSIGEIKAPLSDVSGNANVLIFPTLSAGN
                     IGYKLVQRLAGANAYGPIIQGLNAPVNDLSRGCSVEDIVVLTAITSAQACIDC"
     CDS             17917..18123
                     /locus_tag="ctg1_1710"
                     /transl_table=11
                     /translation="LTDIKYDSKDNMNPLNFYRAVKENRLPLSEKNINDFTNIKLKVSP
                     KLINLLQESSIFYNFSPKKRNTN"
     CDS             complement(19927..20205)
                     /locus_tag="ctg1_1711"
                     /transl_table=11
                     /translation="MYVVVVYDISLDEKGSRNWRKIFGICKRYLHHIQNSVFEGELSEV
                     DIQRLKYEVSKYIRDDLDSFIIFKSRNERWMEKEMLGLQEDKTDNFL"
     CDS             complement(20210..21202)
                     /locus_tag="ctg1_1712"
                     /transl_table=11
                     /translation="MKRSFFLYSNGTLKRKDNTITFINEKDEKRDIPIEMVDDFYVMSE
                     MNFNTKFINYISQFGIPIHFFNYYTFYTGSFYPREMNISGQLLVKQVEHYTNEQKRVEI
                     AREFIEGASFNIYRNLRYYNGRGKDLKLYMDQIEELRKHLKEVNNVEELMGYEGNIRKI
                     YYEAWNIIVNQEIDFEKRVKNPPDNMINSLISFVNTLFYTKVLGEIYKTQLNPTVSYLH
                     QPSTRRFSLSLDISEVFKPLIVDRLIFSLLNKNQITEKSFVKDFEYLRLKEDVSKLIVQ
                     EFEDRLKQIITHKDLNRKISYQYLVRLECYKLIKHLLGEKKYKSFQMWW"
     CDS             complement(21214..21708)
                     /locus_tag="ctg1_1713"
                     /transl_table=11
                     /translation="MDKNITGLMVYYYEVCKRKLWYFVNEIQLEENNSNVILGKLLEEN
                     TYTRDEKKINIDGIINIDFIRSKKVLHEIKKSNSIEPASLLQVQYYLYYLEKKGLIGLK
                     GILDYPLLKQTVEVNLTDKDRENLDNIIIGIKEILRKESPPALEKKSICKKCAYFDLCF
                     V"
     CDS             complement(21751..24189)
                     /locus_tag="ctg1_1714"
                     /transl_table=11
                     /translation="MLDEELLKKYKAKSNKSIFEHNQDLKKQKDVLINLGYLNDKEKIE
                     LLSYAIDYHDSGKFNLKFQRRIEENIKRINGEKYNSKYLKFDKENEIEHNILSAFLINS
                     QDFNSEKEYLAVLYSVIFHHRYSDAISTINNQIFPNIEEILEDNLPNGVVTYEGDIPLE
                     LNFQDLNTVENIKLLGLLMKCDHSASGGYEIEYPNDFLEEALNNLLNEFKEKDKSADWN
                     DMQKFCKENSDKNIIAIADTGMGKTEGGFLWGGNNKIFFVLPLRTAINAMYKRVKLFVP
                     KNKILEEKVGLLHSNSLEYYLNNKKELVIDDKDEKEMDILEYNKRGKHLSLPVTICTPD
                     QIFNFILKYKGYESKLATLSYSKIILDEMQMYDASLLAAVIFGITKIIEMGGKIAIVTA
                     TFPPIIEYFLNKYLMKGNKKAIKDLDKPEEVVEEPIFIKKKFTNNEKIRHNIVLIDDEI
                     GVEQILWKFRKNRKENKKSNKILVICNTIKKAQEIYLKLKEEDDLKDKINMLHSNFIRE
                     DRENKEKEILDFGKTEFDGEGIWISTSLVEASLDIDFDYLFTELQDLNSLFQRFGRCNR
                     KGKKLVDEANCFIYLKIEDKYLKEKGSKYGFIDKDIYENSKKGLENYYEVVSKDEIENS
                     QDYSELFKNYSKQINEGDKIKLIEENLSFENLKESNFVDEFEKAYEKYQRILNSDENSQ
                     DALKLRDIQSVTVIPYDIYEENEENIKELIKKIEDKNLGLEERQNAKTELLKKTLSIQY
                     YQLSKYISEILKGKADANKYKSESINKFEKITVMEADYDKELGFRAKDFKDGIPTYEFI
                     "
ORIGIN
        1 acttgaattt ttagatgatt ttataaaaga ttttaatata aaagatagtg atttaaaaaa
       61 aggaaatata aaaattccaa attttagagc ttatcagtta aatgttcttc aaaataaata
      121 tatggatata gagaaaaatc aagattttaa taaattattt gagcaaaaag ttatagaaat
      181 tccatctaaa tataaaaaaa ttttaagaga gtatcaaatt gttggtgttg aatggatgtt
      241 aaaattaaga gctatgaatt taggtggtat tcttgcagat gatatgggac ttgggaaaac
      301 tttacaagtt ataacatatt tagaaagtgt taaaagagaa agagcttgtt taattgtaac
      361 accagcttct ttaattctaa actgggaaaa tgagtttaat aaatttaatt catcagtttt
      421 aacattatca atttacggtg atagaaaaaa tagagaagtg cttctttcta atttaaaaaa
      481 tgaagtagta ataacttcct atgattactt aaaaagagat atggacttat atgaaaatat
      541 tgactttgat actattatac ttgatgaagc acagtacatt aagaaccata aaacaaaggt
      601 agctcaagct gtgaagaaaa taaattctaa atttaaacta gcacttacag gaacaccatt
      661 agaaaatagt ttggctgaaa tatggtctat ttttgatttt ctaatgaatg gatatctatt
      721 taattatgat tatttttata aaaattatga aaaagctatt gttttacaga ctgaaaagag
      781 agttacagaa agattaaaaa atatggttga accttttata ttgagaagat taaaaaaaga
      841 tgttcttaaa gaattaccag aaaaaattga agaaacatat tatgttgata tgaatcaaga
      901 agagaaaaag ctatatcagg caaatcttat aaaaattaat gaaactttgg ctcaaaatat
      961 agatgtcaat actaataaaa ttgaagtctt agctatgcta acaaaattga gacaaatttg
     1021 tatagatcca agattgctat atgaagatgt aagctcttct tcttcaaaaa ttaatgcttg
     1081 tatagaactg atagaaaaaa gtatagaaaa taatcaaaaa atattattat tttcttcatt
     1141 cacaactgta cttgatttag ttgcacagga atgtgataat ttatcaattc cgtattttat
     1201 gctaacagga gaaacaaata aagtaaaaag aaaagaaatg gttgaaaatt ttcaaaatga
     1261 agcagtacct ttatttttaa tttctttaaa agcaggtgga actggtttaa atttaactaa
     1321 ggcaagtgtt gttattcatt tagatccttg gtggaatata tctgcacaaa atcaagcaac
     1381 agatagagca cataggatag ggcaagaaga tactgtccaa gtatttaatc taattacaaa
     1441 aaatacaata gaagaaaaaa tactaaatct tcagagtaaa aagaaagaat taagtgatat
     1501 ttttgtagaa aattctaagg gaagtttttc aagtttgaca aaagaacagt tgttagattt
     1561 gtttaagttg gaataattgc tattataaaa aaaatatgat attataaaaa agtatttatt
     1621 actataatct ataaaaagaa ggaaaaaaca tggcagaaaa aactcaaaga ataggaatat
     1681 ttgactctgg tttaggagga acaactgtac ttaaagaatt aataaattca cttccaaatg
     1741 aagattacat atactatgga gataatggaa acttccctta tggttctgga aaaactaaaa
     1801 atgaacttca aaaattaact gaaagaattt tagatttttt tgtcaaaaat aattgtaaat
     1861 tagtaatagt agcttgcaat acagcttcta ctgctgctat tgattatcta agagaaaaat
     1921 tctctttacc tataattggt attatagaag caggagttaa aatagcaagt aaaaatacca
     1981 aaaataaaaa tattgctgtg atatcaacta aatttacagc agaatctcat ggctataaaa
     2041 ataaagctaa aatgcttgat agtgagttaa atgttaaaga aattgcttgt attgaatttg
     2101 ctcaaatgat agagacagga tgggatactt ttgataacag aaaggaactt ctaaataaat
     2161 acttatctga aattcctaaa aatgctgata ccttagtatt aggttgcact cattatccac
     2221 ttataagaga agatattgaa aaaaatataa aaattaaagt ggttgatcca gctgtagaaa
     2281 tagttgaaag aactatacaa actttgactt ctcttaatct tttgaatgat aaaaaagaaa
     2341 gagggagaat aatatttttt gtaacaggag aaacatatca ttttaaacca actgctgaaa
     2401 agtttttagg aaaagaaata gaaatttata gaataccaaa ataaaaaaag ttttagctca
     2461 taattaaaat aatttagaga atttttttaa gaataaaact cttaaaaaga ttctcttttt
     2521 atatgattta aaattttctt gctaaaaata taaatttcaa aggtagacta ttttagttca
     2581 atttgttata atgtattagg tttaatataa atatttgaaa ggagaggaac attgcgagta
     2641 aaatgctttc atttaggagc ttatggaaca aattgtttct tagcttatga tgaaaataat
     2701 atagcttatt tttttgattg tggaggacgc aatttagaaa aagtttatga atttataagt
     2761 gaacataatt tagatttaaa atatatagtg ttaacacatg gacatggaga tcacattgaa
     2821 ggtcttaatg atttagcttc tcactatcca gaagcaaaag tgtatattgg tgaagaagat
     2881 aaagattttt tgtataattc tgaacttagt ttatcagatg ctatttttgg agaatttttt
     2941 aaatttaaag gagaaattca tactgtaaaa gaaagtgaca tggtaggaga tttcaaagtt
     3001 atcgatactc ctggacatac tatcggttca aagagtttct actatgaaaa agataaaatt
     3061 ttaatatcag gagatacatt gtttagaaga agttatggac gatatgattt acctactgga
     3121 agtttagaaa tgttatgtca tagtttaaaa aaattatcaa aattaccaga tgaaactgtt
     3181 gtttacaatg gacatacgga taatacaact attggagaag aaagaagatt tttagaaaga
     3241 gttggaatac tttaaaaaat ttaaggagag aaaaataatg gaaaaaatat atgatgttat
     3301 aattgttgga gctggtcctg ctgggctaac agctggaata tatgcaggaa gaggaaattt
     3361 atcaactctt attttggaaa aagaaggaat aggaagtatg ataatgactc atcaaataga
     3421 caactatcct ggttctcata ttggagcctc tggaaaagaa atttatgata caatgaaaaa
     3481 acaagcctta gactttggtt gtgaaataaa acctgcaaca gttttaggat ttgaccctta
     3541 tgatgaaatt aaagttgtaa aaacagatgc aggaaatttt aagacaaaat atattataat
     3601 agcaactgga ttaggtaaaa ttggtgctaa aaaggtaaaa ggagaaaata agtttttagg
     3661 tgcaggtgtt tcttattgtg caacttgtga tggagctttt acaaaaggta gagttgtttc
     3721 attggtcgga aaaggtgatg aaattattga agaagcttta tttttaacta gatatgcaaa
     3781 ggaagtaaat atctttttaa cttctgatga tttagattgc aatgaagaat taaaagaagc
     3841 tattttatca aaagaaaatg taaaaattac aaagaaagta aaacttttag aaataaaagg
     3901 agaagaattt gtaacagaat tagaattgga aatagctggc aataaagaaa ctatatcaac
     3961 tgattttgtt ttcttgtatt taggtacaaa aaataatatt gaattatatg gagaatttgt
     4021 taatttaagt gaagcaggat atataataac agatgaaact atgaaaacaa gaactgataa
     4081 aatgtatgct attggagata taagagaaaa agatgtaaga caagttgcca ctgccactaa
     4141 tgatggagta atagcgacaa cattcatttt aaaagaaata ctaaaatcta agaaaaaata
     4201 aaatattaat tataggagct agctatgaaa cattatattg gtattgattt aggtggaacc
     4261 aacacaaaaa taggagtagt tgattcagag ggaaatttga taaatagcaa aattattaaa
     4321 actcactctc atcaaaatgt tgataaaaca cttgaaagaa tttgggaaac tgcaaaaaaa
     4381 ttgatattag aaaaagaaat tccacttttt tctgttgtag gaataggaat tggtattcca
     4441 ggacctgtaa aaaaccaaag tacagtaggt ttctttgcaa attttgattg ggaaaaaaat
     4501 cttaatttga aagaaaaaat ggaaaagtta agtggaatag aaacaagaat tgaaaatgat
     4561 gctaatataa ttgcacaagg tgaagctatt tttggagctg caaaaggaaa aaaatcttca
     4621 ataactattg caataggaac aggaataggc ggaggaattt tttataatgg aaaccttatt
     4681 tctggtatgt ctggtgtagg tggagaaata ggacatatga aggtggttaa agatggtaaa
     4741 acttgtggtt gtggacaaaa tggttgtttt gaagcttatg cctcagctag ctctcttgtt
     4801 aaagaggcaa aagagagatt aaaattaaat gaagataatt tactttttaa ggagattaat
     4861 ggagatttag atgaacttga agcaaaaaat atttttgatg ctgctagaaa gggagatcaa
     4921 ttttcaaaag atttaataga atacgaaagt gattatttag ctttaggaat aggaaatctt
     4981 ttaaatataa taaatcctga atgtattgtt ataagtggag gtatttctct tgcaggagat
     5041 gaaattttac ttccaataaa agaaaaatta aaaaaatata ctatgcctcc tgctcttgaa
     5101 aatttagaaa ttaaaatagg gactttgggt aatgaagcag gtgtaaaagg agctgtggca
     5161 ctttttattt agatattaat taagtaaaat agcaaaaatt atttgtcata taaaaataca
     5221 ttttttctaa aatatggaaa atttatttat ttttaataaa aatctattga caaaaggcaa
     5281 caaaaaatta tatattgtat tatatatgga aatatataat acaaataaag aattattatt
     5341 ttattaaatt atttaggagg gtatttatat gaaaaagttc ggtatgttat tgggttcaat
     5401 tattcttgca tcagcactag ttgcttgtgg agaaaaaaag gaagaagcta aaactgatgc
     5461 tcctgctaca gaaaaattat caataggatt aactgcttat aaatttgatg ataactttat
     5521 agctctattt agaaaagcat ttgaagctga agcagcagct aaagctgata tagttgcagt
     5581 aactgctata gactctcaaa acagtgttgc tactgaaaaa gaacaaatag aagcagttct
     5641 tgaaaaaggt gttaaagctt ttgctataaa tctagttgat gcctctgcag cagatggaat
     5701 tatcaattta ttaaaagaaa aagatgttcc agttgtattc tataatagaa aaccttctga
     5761 tgaagcaata gcttcttatg ataaattatt ctatgtagga attgacccta atgctcaagg
     5821 aattgcacaa ggtgaattaa ttgaaaaatt atggaaagaa aatcctgatc ttgacttaaa
     5881 taaagatgga gttatccaat atgtaatgtt aacaggagaa cctggacacc cagatgcagt
     5941 tgcaagaact aaatattcta tttctacttt aaatgatcat ggagtaaaaa cagaagaatt
     6001 acaccaagat actgctatgt gggatactgc tactgcaaaa gataaaatgg atgcttggtt
     6061 atcaggacct aatggttcta aaatagaagt agttatctgt aataatgatg gaatggcttt
     6121 aggagctgtt gaatcaatga aagccgctgg aaaagtttta cctacatttg gtgttgatgc
     6181 attgccagaa gctctagtta aaatagaagc tggagaaatg gcaggaactg ttcttaatga
     6241 tgcaaaaggg caagcaagtg caacattcaa tatggtagtt aatttagcac aaggaaaaga
     6301 agctactgaa ggaactgacc taaaattaga taataaaata atattaattc ctagtattgg
     6361 aatagacaaa tctaatgttg cagacttcaa ataagaatta attgtatagt aatcttaaag
     6421 gagattgtac atcaatctcc tttttttaaa aatggaaaat aaaggaaaag gaataggata
     6481 tttatggaaa atctaaaata tgtattagaa atggaaaata tttccaaaga gtttcctgga
     6541 gtaaaagcac tagatgatgt tcaattaaaa ctaaaacctg gaactgtcca tgctctaatg
     6601 ggagaaaatg gagctggaaa atcaacatta atgaaatgtt tatttggaat ttatgaaaaa
     6661 aatagtggga aaattttatt agatggagta gaagttaatt tcaaatctac aaaagaagcc
     6721 ttagaaaatg gtgtttctat ggttcaccaa gaattaaacc aagttttaca aagaaatgta
     6781 cttgataata tttggcttgg tagatatcca atgaaaggat tttttgtaga tgaaaagaaa
     6841 atgtataatg atacaattaa catctttaaa gatttagata ttaaagtaga tcctagaaaa
     6901 aaagtggctg atttacctat tgctgaaaga caaatgatag aaatagctaa agcagtatca
     6961 tataaatcaa aagtaatagt tatggacgaa cctacttctt cgttaacaga aaaggaagtt
     7021 gatcatttat ttagaattat caaaaaatta aaagaaagtg gagttgggat tatttatatt
     7081 tctcataaaa tggaagaaat aaaaatgatt tctgatgaaa ttactatttt aagagatggt
     7141 aaatggatat caactaatga tgtttcaaaa atttcaactg aacaaattat aagtatgatg
     7201 gtaggtagag atttaactga acgtttccct aaaaaagata ataaagctaa ggaaatgata
     7261 ttagaagtta agaatttaac tgctttaaat caaccttcta tacaagatgt aagttttgaa
     7321 ctttataaag gagaaatctt aggaatagct ggacttgttg gttctaaaag aacagaaata
     7381 gttgaaacta tttttggaat gagaccaaaa aaacatggtg aaattatttt aaatggtaaa
     7441 actgtaaaaa ataaaagtcc agaagatgct ataaaaaatg gttttgcctt agtaacagaa
     7501 gaacgtagaa gtacaggaat attttcaatg ttagatgtag catttaactc tgttatctct
     7561 aacttagata gatataaaaa taaatttaga cttcttaaaa ataaagatat agagaaagat
     7621 acaaaatgga tagtagatag tatgagagta aaaactcctt catactctac caaaatcgga
     7681 agtctttctg gtggaaatca acaaaaagta attattggaa gatggctact aactgaacca
     7741 gaagttctta tgcttgatga acctactaga ggtattgatg ttttagcaaa atatgaaatt
     7801 tatcaattaa tgatagatct tgctaaaaaa gataaaggaa ttataatgat ttcttctgaa
     7861 atgcctgaac ttttaggagt aacagataga atacttgtta tgagtaatgg tagagttgca
     7921 ggaattgtta aaacatctga aactaatcaa gaagaaataa tggaactatc agctaaatat
     7981 ctataaaaat taagaaggag aataagaaat gattgcaaga actaatgaag gaaaaataga
     8041 ttataaaaaa attattatag aaagtggact gtatcttgta ttattttgta tgcttgttgc
     8101 aataataata aaagagccta cttttttaag tttaagaaac tttaaaaata ttcttacaca
     8161 atcatctgta agaacaatta ttgcacttgg tgttgctgga cttatagtaa cacaaggtac
     8221 tgacttatca gcaggtagac aagttggact ttctgctgta atttctggaa cacttttaca
     8281 atcaatgaca aatgtaaata aagcatttcc aaaattagga gaattttcaa tatttacaac
     8341 tatattgatt gttgttgtag ttggtgtagt tatagcaagt ataaatggag tggttgttgc
     8401 tacattaaat gttcacccat ttatagctac tatgggaaca atgactattg tgtatggaat
     8461 aaactctctt tactatgata aagcaggagc tgctccaatt tctggatttg tagaaaaata
     8521 tagtaaattt gcacaaggtt atataaaaat aggctcatat acaataccat atttaattat
     8581 ctatgcagct attgcaacat taattatgtg gactttatgg aacaaaacaa agtttggtaa
     8641 gaatgtattt gcagttggag gaaatccaga agctgcaaaa gtatcaggag taaatgttgt
     8701 tttaactctt atgggaattt atgcattatc tggagcgtat tatgcttttg gtggtttctt
     8761 agaagctgga cgtattggtt ctgcaactaa caacctagga tttatgtatg aaatggatgc
     8821 tatcgctgcc tgtgtaattg gtggagtttc attctatggt ggtgttggta gaatttctgg
     8881 agttatcaca ggagttataa ttttaacaat tataaactat ggacttactt atacaggtgt
     8941 tagcccatac tggcaatata ttataaaagg tataataatt gttactgctg ttgcatttga
     9001 ctctattaaa tatgctaaga aaaaataaga attaaataat atgaataaat ttttaaggga
     9061 ttgctaatat tttaacaatc cctttctata tttttaaaaa ctaaaaatac tataattata
     9121 atagctacat tatcaattat atatgtaaca tcagcaccaa tatatgatga taaataacct
     9181 gcaactacac ttcctagtcc ataacaagca actgaaaatc caaataattt ttcagatatt
     9241 tgatattttt ttattaaaat tccaggatta attatctcat cattatttgc tataaaaaaa
     9301 tttaaaaaca tagctaatat aaaaaaatta aaaataattt ttttactctt tatatagctt
     9361 attccttctt taaaatcttt aaagaaactt gatttttctt ttgataaatt agtatttttt
     9421 tcatatttta taaatagttc ttgtaaaaac gataaaaaat aagctaagga tataattatc
     9481 aaaacaaaat taaaagtaaa tgtagcaaat agataagttc caacaactgg tccaaaaatc
     9541 ataactgcat tttctaaaaa actttgtaaa ccattatatt tttcaagtgt ttcaggagta
     9601 ttaatttctg aaaataatac cttagaggct atctcaaaaa attttgaaat aatatttaaa
     9661 attaatgaaa ctataagtaa aaaaattacc gaattagaat ttttaaaata taaaaatgga
     9721 ataaaatata acattgaggt tagaaaatca catatcaaaa ttatattctt tttattaaat
     9781 ttctctatta atgttcctat aagtggtgaa ataattattg taggaaggtt aatagaagca
     9841 aagaaaatac ctgttgtttt taaattttga gtaatattta atatatacaa tggtaaaact
     9901 atcagataaa ttgtatttcc aaataaggat actactctac ctaataataa cagttttata
     9961 ttactttctt tgctctgcac tttaacctct atagatattt ttatactatt ttataagatt
    10021 ttccaacctc aatatatttt ttcattacag cacaagcatc ttcaaagcct tttctttctc
    10081 tttcatctaa aggaagctct aagatttctt ctactccatt acttccaata atggctggaa
    10141 ctcctgtata gaaacctgaa tgtccatatt caccatttaa ataagcacta catggtaaaa
    10201 ctcttctttc attatggaaa attgctttca ctaaattaga gcaagtacaa cctattccaa
    10261 actctgtaca attttttcca gaaataatat cccaagctgt tctaactact tgtttttcta
    10321 aaacagaaag ttctactcct ttaaattgtt ctggatgagt tttcatataa tctaaaaatg
    10381 gaactccttg tattgtagca cttgaaaagt ttgctatttg tgtatctcca tgttctccta
    10441 acatgtatgc ttgaataact tggctatcaa tatttgtaac ttcacttaaa attcttttta
    10501 accttgcact atctagacct gttcctgttc caataactct gtttttaggg aagcctgaaa
    10561 gctctcttac aaaataagtt actatatcaa ctggattagt tattgtaaca aaaattccat
    10621 taaatcctgc ttttacaaca tcaggaacaa aactttttat agcttctaat gagcctttta
    10681 attcttccaa tctttgttca ttttttgtta aacttccaac actgattacg attacatcca
    10741 tttttgaaag ctcttgaatt cctccatcac gaataatagc tctatgagga agaaaactta
    10801 tagtgtccat acaatctatt gcatgagctt ttgctttttc tggaataata tccattaaaa
    10861 ccatttcatc acatacacct tgtaataaca tagataaggc acaatgactt ccaacatgac
    10921 caattccaac aattccaact tttcttgttt gtaacatata aaaactcctt tcagtttaaa
    10981 ataattcgct gattatatta taacaaaaag aactattata aagcaataat ctcttttaaa
    11041 taattataaa taagaaaaaa ttataacaaa aaagagttgc tatgaaataa tttcataaca
    11101 actctcactc ttaacaatta tttaatttta ttcagcttct ttttcttcac tataatctag
    11161 tgcagccatt ctcttatatt gtctccatct cttttgagca tcttttttat ttgtttcaaa
    11221 taaattttta gcttcttctg gatttgattt tgctagagtt tgatatctta cttcaccagt
    11281 tagatattct tcatattttt cccatttagg ttctttagaa tctatttgta aaggattctt
    11341 acctattttt tctagtgatg ggttatatct aaatattggc caatatccac attcagtagc
    11401 aagtttcatt tcagtttgag actttgacat acctttctta ataccatggt tgatacaagg
    11461 tgagtatgca ataattattg aaggtccttg gtgagcttct gcttccttaa cagctttaat
    11521 aaattgttgt tgattagctc ccatagaaac ttgtgctaca taaatatgtc cataagacat
    11581 tgctattgca gctaaatctt ttttcttaac tggttttcct gctgctgcaa acttagcaac
    11641 tgatccagta ggtgtagctt ttgatgcttg tccaccagta tttgaataaa cttctgtatc
    11701 cattactaat acatttatat cttcattaga tgcaagcaca tgatcaagtc caccataacc
    11761 aatatcataa gcccatccat ctccaccaat tatccattga gattttttaa ctagatattg
    11821 ttttaaatcc aagatttctt ttgcaaaatc tgttcctaat gcttctaatt ttggaacaag
    11881 aatatctcta acttctcttg ttcttacaga atattgtcta tttgctatcc aatctttgaa
    11941 taaagtagct atatcttcat caactttatc catattttct tccatagtat gttgaattct
    12001 aaatcttaat gcttcaactc ctacatgcat accaaatcca tattcagcat tgtcttcaaa
    12061 taatgaagat ccccaagatg gtccttcacc atttttatta gttgtatatg gagttgcagg
    12121 agcagaacct gaataaattg aagaacatcc agttgcattt gcaaccatca ttctatctcc
    12181 atataattga gttatcaatt taatataagg tgtttctcca caaccaggac atgctccatg
    12241 gaattcaaat aatggttgag agaattgaga accttttaca gtatcaagtg gcattaaatt
    12301 acttctatat tcaacattat tatataaata atttgtattt atgtcttcat gtgtttctaa
    12361 tgattcagct attggtctca tatctaaagc atttgcagga caaacattag cacaagatcc
    12421 acaaccaaca caatcaagag ctgatacttg tattctatat actaattcat ctaatccttt
    12481 tcctgttgct ttctttgtag caaaagaatt tggagcagct tttaattcat cttcatttat
    12541 taagaatggt cttattgcag catgtggaca cacataagaa cattggttac attgtataca
    12601 tttatcaaca ttccaaatag gaacatctac tgcaactcct cttttttcaa atgcagaagt
    12661 accattttca aaagtaccat cttcatatcc taagaaagct gatactggta aatcataacc
    12721 ttttattgca tttactggtc ttactatttt cttaacaaat tctgtgtcag gttgacaata
    12781 agcacaacct gttgtttctt taggctcatt tagtggggtt acttcaagat ttgcccatgc
    12841 tggatcaact tctatttcaa taatatcgtt tgctcctcta tctattgcat tatagttaag
    12901 ttgaactatt tcatcacctt ttttagcata agatttttta gcataatctt tcatatattg
    12961 ttgtgcttct tcaaaaggaa taatttcagc taatttgaag aaagctgctt gcattatcgt
    13021 atttgttctt tgtcctaaac caatttcttg tgcaagagca gtagcattta taataaataa
    13081 tcttgcttta tttttagcca aatctctttt tacattattt ggtatattag ctattgcttc
    13141 ttcttttgtc catacacagt tcaataagaa ttttccacct tctttaagtc cagatgtcat
    13201 atcatattgg tttaaatatg ctggaactga acaagcaaca aatgttggtc ttgatactaa
    13261 ataagttgat ctaataggtt ttttaccaaa tcttaagtga gatctagtaa ctcctcctga
    13321 ttttttagag tcataagcaa aatatccttg tgcatacaag tcagtcttat ctccaattat
    13381 tttaatagag tttttatttg ctccaactgt tccatctgct cctaatccat agaataaaca
    13441 tgcttttgtt gttggatctg caagtgccat agctggtcct acttcaagtg aagtatgagt
    13501 tacatcatct actataccaa ctgtaaatgc atctttaggt gtatcttttg caaggttatc
    13561 aaatacagct tttatttgag ctggagttgt atcttttgaa gacaacccat atcttccacc
    13621 aactattaat ggagcatttt ctttattata gaacaatgct tttatatcaa gtaataaagg
    13681 ttctcctaat gaaccaggtt ctttagttct atctaaaact gaaattcttt ttgctgtttt
    13741 tggtaaaata tcaaagaaat atttagcaga gaaaggtcta aataaatgta cagatattaa
    13801 accaactttt tctccttttt ctactaagta atctataact tcctgtgctg cttcacatac
    13861 tgatcccatt gcaattataa ctctttcagc atctggagca ccataataat taaatggttt
    13921 gtattctctt cctgtaattt ttgatatttc tttcatatag tcagcaacta tatctggaac
    13981 agcatcataa aatttgtttt gtacttctct tgcttggaag taaatatcat cattttgtgc
    14041 tgtacctctt gttactggat gttcaggatt taatgctctt tttctaaatc cttctaatgc
    14101 tttccaatct actaatttct ttaaatcttc ataatccatt acttctactt tttgaatttc
    14161 atgagaagtt ctaaatccat caaagaagtg taaaaatggt actcttgact tcaatgctga
    14221 taagtgagct acaccagcta aatccattac ttcttgtact gaatttgttg caagcatagc
    14281 aaatccagtt tgtcttgctg cataaatatc ttggtggtca ccaaagattg ataatgcttg
    14341 tgcagataat gatcttgcag atacatgtat aacacctggt aataattcac cagctatttt
    14401 atacatatta ggaattttta aaagtaatcc ttgtgatgca gtataagttg ttgttaatgc
    14461 cccagcttgt aaagacccgt gaactgttcc agcagctcct ccttctgatt gcatttcaac
    14521 taattttact ggaactccaa aaatattttt cattcctttt gctgcccatt catctgtata
    14581 ttcagccatt ggtgaagatg gtgttatagg ataaattcct gccacttctg taaaagcgta
    14641 agatgcgtat gcagcagctt ggtttccgtc catagtttgc attttttttg ccatatagtt
    14701 tcctcctaat ttctaaacat ttacttgttt aatttctatc atttcacaat ttaatttata
    14761 taaaaataat tctatatttt ctctgttatt ttgctagtct aaaagtatct cttgctatta
    14821 ctaattcttc attagtaggt attttatata ttaaaacttt tgaactatcc ttagataatt
    14881 ttacatttcc tttttttcta actgagttaa tttctttatc taattctaca cctaaaaatt
    14941 ctaaaccttc taatgctttt tctcttgtca ttgaagaatt ttctccaatt cctcctgtaa
    15001 agcatatagc atctactcca cccataatag ctgcataagc acctatatat gatcttaatc
    15061 tatgcataga aacgctttca gcaagtattg ctctttcatc tccttcaaca actgcatttt
    15121 ctaagtctct acaatcagat gattttccaa ataatccaag aattccagat tttttattca
    15181 ttctatcatc catttgagca tctgtaagcc ctcttttatt tttaacaaat agtacagctg
    15241 caggatctat atctccacat cttgttccca tcattaaacc ttgtagagga gttaatccca
    15301 ttgaagtatc aactgacttt ccatctttaa cagcagttat tgatgctcca tttcctaagt
    15361 gacaaacaat tatttttgaa tgttcaggat ttcccataat ttctctcata attccagata
    15421 catacaagtg agatgttcca tggaaaccat attttctaac ttttaattct ttataatctt
    15481 catatggtaa tggatacata aatgcttctg gtttcatagt ttggtggaaa gcagtatcaa
    15541 atacagcgac atttttctta ccgggcataa gttccataca agttcttatt cccattaaat
    15601 ttgctggatt atgtaaagga gctaggtcat tatttgcttc aatagctttt aaaacagcat
    15661 cattaattaa aactgattgt gcaaattctt cccctccatg tactacccta tgtcctattg
    15721 catcaacttc atctactgag gctataactc ctatttcttt atcagttaaa tgagatatta
    15781 ctaattctaa tgcttctttg tggcttggca taggagtttc taattttttt tcaaaatctt
    15841 ttgctacaac ttcgtattcc aacttagaac catctattcc aattctttca caaagtcctt
    15901 ttgcgaaaac ttcttcagtt tctggattta ttaattggta ttttaatgaa gaacttccac
    15961 aatttattac tagtattttc atttatattt tcctccatct aatttttata tttatattac
    16021 agaatttttt tattaacaat ctatacaagc ttgtgcagaa gtaatagcag ttaatacaac
    16081 tatatcttca actgaacatc ctcttgataa atcatttact ggtgcattta atccttggat
    16141 aattggtcca taagcattag ctcctgctaa tctttgaacc aacttatatc caatatttcc
    16201 agcagataat gtagggaata ttaagacatt tgcattacca gatacatcag ataaaggagc
    16261 ctttatttct ccaatagatt ttactaaagc cgcatctgct tgtaattcag catcaaatct
    16321 aaattgtact tttctttctc ttaaaatatg tcctgcttct ataactctat ccacacattc
    16381 atgttttgct gaaccttttg ttgagaatgt catcaatgct actcttggat ttatccctgc
    16441 tattttaatt gctgtttcag ctgcagaagt agcaatatca gccaattgtt ctgaagttgg
    16501 gaatggaata actgaacaat ctccaaatac taagatactt ccaaataaat ctttaaattg
    16561 agataattcc ataatgaaaa cagatgaaac tgtctttact cctggttgag tccctataac
    16621 ttgaattgct gctcttaata catttgcagt tggtgatgca gatccagata ccattccatc
    16681 agcatctccc attcttacta acatagctcc aaaaaaagta ggatcattta ataatatttt
    16741 ttttgcttct tcaggagtca tccctttttt agctcttaat tcaactaact tattaatata
    16801 gtcatttaat ctttcaaaat tataaggatc tacaattttg gctccactta atgaaacttc
    16861 ataagccttt gcactatgca ttattgcttc ttgatttcct acaagaacaa cttgagctaa
    16921 accttctttt aaaatttgag aagttgctcg gattattctt tcatcacttg attcaggtaa
    16981 aactattctt ctgtttgctt gtaaggcctt ttttctaact tgccctaaaa aactcattat
    17041 aatcactccc tatttttagt agataaaact ttaaatttat cttttaaatt tattaagtat
    17101 atattaacac caattacgat taaatgcaat aattttattg taaaattcac tcaattttta
    17161 ataaaatttt atcattttaa tattcagtaa ctttcttttt ctatttttaa aagaattatg
    17221 ttcattattc taatatttta gttggaattt atctttttat tttttttatc actttaaaga
    17281 tacttaattc ttagtttact ttataaagat atacttaaca taataaaaat taatccattt
    17341 aattggcttt tactttttta catttttata aactattttt atttcataaa gttccttcat
    17401 aaagttccta taataaaaaa tcttcatttg aaactttaat aggatatttt tactcatata
    17461 tattgaagtt ttttatgaaa tgtatttaaa attttcttat tgtattctta aaaaatgata
    17521 ttgtttacta tcttcataga ccactactac ttttatatac tttacataat ttaaatccct
    17581 cacttagata tttatacatg ttcaatttaa ttatataaaa ataatatcga attcttcaaa
    17641 aagtatgata taatgagtta acaaaactga tatgtaaaag atctgacagt tggcaggcaa
    17701 cggaaaaacc tgaagataag ttaatttgag agtgtctgtt caaggacact cttttttaga
    17761 ggttataata gaaaatcgta aaatttttaa aaaattaaag ttagctcaag aagtttatga
    17821 taagaatttt ttaaataaga gggtttcata catttatgaa aataaaaatg aaataaaaaa
    17881 attcctaatt acttttaaga agcatttttt ttacatttga cagatataaa gtatgattct
    17941 aaagataata tgaatccatt aaatttctat agggctgtga aagaaaatag attaccttta
    18001 tctgaaaaaa atattaatga ttttacaaat attaaattaa aagtatctcc taaattaata
    18061 aatcttttac aagaaagttc aattttttat aatttttcac ctaaaaaaag aaatacaaat
    18121 tgactatata tcgactcttt tattacagaa aatcaaagaa acaaaaagtc aatcattttt
    18181 agaataataa aaaaagagga aaatacaagt aattattttc catcttctat actaagaact
    18241 attcctgagg aaaaaggaaa ttacattgga aatgttttaa ttattgcttg tagaaattgt
    18301 aatttaaaaa agaaaaaata taaagcaatc tatagagtaa cagatgcatc taaaattcct
    18361 gatgaattaa agaaagatat ttcagattta gaaaacctat aattgtctta caggaaatcc
    18421 aatagaatat acaaaattta aaaattttga aaatagttgt attgcaaaaa ttgacttgaa
    18481 aaaatatgga atagaaaaaa agaaagtgat atagagggaa ctcagataag catagggttt
    18541 atagaggaag aaaaagtaac agaaaaatta aaaggattaa ctcctgcttc ttacagaagt
    18601 caatccttat tagtaagtta aattaaattt gtctaacttt ttggggtcag tacattttaa
    18661 atacataaat ttattctttc cctgcaatca tttatatctt gttcgatatt taaattctaa
    18721 tatagaaata cataaatttc tataaatttc aaatgtctta ctatctttcc atatttaaat
    18781 tctaatatag aaatacataa attaaaaaac tcctatcaga aaaattacct tttttaatat
    18841 ttaaattcta atatagaaat acataaatga agtgcttttg tagaatattt aaagtattga
    18901 aaaatttaaa ttctaatata gaaatacata aatcttagaa caaagagcag aattattaaa
    18961 aaattctcat ttaaattcta atatagaaat acataaattt tatcagaagc ttttgaatta
    19021 ccagttgtag tatatttaaa ttctaatata gaaatacata aataaattga acaggaaaat
    19081 ttaaaaaata aagaaaaaaa tttaaattct aatatagaaa tacataaatt tgctctgtat
    19141 cttttattag ctttgttttg ttgttccatt taaattctaa tatagaaata cataaatata
    19201 tagtatgtat catcaattaa atacgcttct tcatttaaat tctaatatag aaatacataa
    19261 atgagaactt actacaaagg tgggaatcca gtcaaaaaaa tatttaaatt ctaatataga
    19321 aatacataaa taagagattt tttatttgaa ttagctaatg aagctacatt taaattctaa
    19381 tatagaaata cataaattag attattgact tcatttaatc ctggaatagt tacatttaaa
    19441 ttctaatata gaaatacata aattaaaaaa cttctttgaa attataacca ctgtcagatt
    19501 tatttaaatt ctaatataga aatacataaa tgaatacttg aatcttttaa cttaaacatc
    19561 tgtaatactt atttaaattc taatatagaa atacataaat ctgttgattc aaataataaa
    19621 ttagttggaa gtagatttaa attctaatat agaaatacat aaattcaaaa atacattatg
    19681 tcaatgaatt aactcaaaac tcatttaaat tctaatatag aaatacataa atagctagct
    19741 aaaaaaacta ctcctacata atactttttt tatatctttt tgtcaatgta agttttttta
    19801 ctaaaaaata aaaaacttta atttcttata attttttatt ttcttaaatt tatttataaa
    19861 taaacacatt tataactttt gtcaatcttc cagtaatttt acattatcag aggtagacaa
    19921 taaattttat aagaaattat cagttttatc ttcttgtaaa cctaacattt ctttttccat
    19981 ccatctttca tttcttgatt taaaaattat aaaagaatct aaatcatctc taatatattt
    20041 tgaaacttca tattttaatc tttgaatatc aacttctgat aattctcctt caaagacaga
    20101 attttgaata tggtgaagat atcttttaca aattccaaaa atttttctcc aattccgact
    20161 acctttttca tccaatgaaa tatcatacac tacaactaca tacattttat caccaccaca
    20221 tttgaaaaga tttatatttc ttttcaccta ataaatgttt aataagttta taacattcca
    20281 gtctcactaa atattgataa gatatttttc tatttaaatc cttatgagtt attatttgtt
    20341 ttaatctatc ttcaaattct tgaacaataa gtttagaaac atcttctttt aatcttaaat
    20401 attcaaaatc tttcacaaaa cttttctctg taatttgatt tttatttaat aatgaaaaaa
    20461 ttaatctgtc cactatcaat ggtttaaata cttctgaaat atcaagtgaa agagaaaatc
    20521 ttcttgtact aggttgatgt aagtaactaa ctgttggatt tagttgtgtc ttataaattt
    20581 ctcctaatac ctttgtataa aaaagagtat ttacaaatga tattaaagaa ttaatcatat
    20641 tatcaggagg atttttaact ctcttttcaa aatctatttc ttgatttaca ataatattcc
    20701 aagcctcata ataaattttt ctaatgtttc cttcatatcc cattaattct tcaacattat
    20761 ttacttcttt taaatgcttt ctaagttctt ctatttgatc catatagagt tttaaatctt
    20821 ttcctctacc attatagtat ctcaaattac gataaatatt aaatgaagca ccttctataa
    20881 attccctagc tatctctact cttttttgtt catttgtata atgctcaact tgttttacta
    20941 aaagttgtcc tgaaatattc atttctcttg gataaaaact tcctgtataa aaagtataat
    21001 aattaaaaaa atgtattgga ataccaaatt gggatatata attgataaat ttagtattga
    21061 aattcatttc agacataaca taaaaatcat ctaccatttc aataggaata tctctttttt
    21121 catctttttc attaataaat gttatagtat tatcttttct tttcaatgtt ccattgctat
    21181 aaagaaaaaa acttcttttc atattaaccc ctcctataca aaacataaat caaaataagc
    21241 acatttttta caaatacttt ttttctctaa tgctggaggg ctttccttcc ttaaaatttc
    21301 ttttattcct attattatat tatctaaatt ttctctgtct ttatctgtta aattaacttc
    21361 aactgtttgc tttaatagtg gataatccaa aattcctttt aatccaatta atcctttttt
    21421 ctctaaataa tacaaataat attgaacctg caataaagaa gcaggttcta ttgaattact
    21481 tttcttaatt tcgtgtaata ccttttttga acggataaaa tcaatattta taatcccatc
    21541 tatattaatt tttttctcat ctctggtata agtattttct tctaaaagtt ttcctaaaat
    21601 aacatttgaa ttattttctt caagttgaat ttcatttaca aaataccata actttctttt
    21661 acagacttca taataataaa ccatcaatcc agttatattc ttgtccataa tatctatctc
    21721 cccatagttt aattaataaa gtattatttt ttagataaat tcataagttg gaatgccatc
    21781 tttgaaatct tttgcacgga aacctaattc tttatcataa tcagcttcca taactgttat
    21841 tttttcaaat ttattaatac tttctgactt atatttattt gcatcagctt taccttttaa
    21901 aatttcactt atatacttac ttaactgata gtattggatt gaaagagtct tctttagaag
    21961 ttcagtttta gcattctgtc tttcttctaa acctaaattt ttatcttcta tcttttttat
    22021 aagttccttt atattttctt cattttcctc ataaatatca tatggaatta cagtaacact
    22081 ttggatatcc ctaagcttta aagcatcttg tgaattttca tcactattta aaattctttg
    22141 gtatttttca taagcttttt caaattcatc aacaaaatta ctttctttta aattctcaaa
    22201 acttaaattt tcttctataa gttttatctt atctccctca ttaatttgtt tagaataatt
    22261 tttaaataat tcactatagt cttgtgaatt ttctatttca tctttagata ctacttcata
    22321 gtagttttct aaaccttttt ttgaattttc ataaatatct ttatctatga aaccatattt
    22381 agaacccttt tcttttaaat atttgtcttc aatttttaaa tatataaaac aattagcttc
    22441 atctactaat tttttacctt tacgattaca tcttccaaat ctttggaata atgaatttaa
    22501 atcttgtaac tctgtaaata aataatcaaa atcaatatct aatgaggctt caacaagtga
    22561 agttgatatc caaattcctt caccatcaaa ttcagttttt ccaaaatcta aaatttcttt
    22621 ttctttgttt tctctatctt cacgaataaa gtttgagtgt aacatattaa ttttatcttt
    22681 taagtcatct tcttctttta attttaaata aatttcttgt gcttttttta tagtgttaca
    22741 gataaccaaa attttattag actttttatt ctcttttcta ttttttctaa atttccataa
    22801 aatttgttct accccaattt catcatcaat aagcactata ttatgtctta ttttttcatt
    22861 attagtaaat tttttcttta taaatattgg ttcttcaact acttcctcag gtttatccaa
    22921 atcttttatt gcctttttat tacctttcat taaatattta tttaaaaaat actcaattat
    22981 tggaggaaaa gtagcagtta caatagcaat tttacctccc atttctataa ttttggtaat
    23041 tccaaaaatt acagctgcaa gtaaactcgc atcatacatc tgcatttcat ctaaaattat
    23101 tttagaataa gaaagagttg ctaatttact ttcataacct ttatatttta aaataaagtt
    23161 aaatatttgg tcaggtgtac agatagtaac aggtagagat aaatgtttac ctcttttatt
    23221 atattctaaa atatccattt ccttttcatc tttatcatca attacaagtt cttttttatt
    23281 attcaagtag tattcaagag aatttgaatg caatagtcca actttttctt ctaaaatttt
    23341 attttttgga acaaaaagtt taactctttt atacattgca ttaatagctg ttctaagagg
    23401 tagaacaaaa aatatcttat tatttcctcc ccaaagaaaa cctccctcag ttttacccat
    23461 tcctgtatct gctattgcaa ttatattttt atcactattt tctttacaga atttttgcat
    23521 atcattccaa tcagctgatt tatctttttc tttaaattca tttagcagat tgtttaaagc
    23581 ctcttctaaa aaatcattag gatattctat ttcatatcct ccactagctg aatgatcgca
    23641 tttcataagt aaacctagta attttatatt ttctactgta tttaaatctt ggaaattcaa
    23701 ttctaaaggt atatctcctt cataagttac tactccattt ggtaagttat cttctaaaat
    23761 ttcctctata ttaggaaaaa tttggttatt tattgtacta attgcatctg aatatctatg
    23821 gtgaaatata actgaataaa gtactgctaa atactctttt tctgaattaa aatcttgtga
    23881 atttattaaa aaagctgaaa gaatattatg ttctatttca ttttctttat caaattttaa
    23941 atatttagaa ttatattttt ctccattaat tctttttata ttttcttcta ttcttctttg
    24001 aaatttcaga ttaaattttc cactatcgtg ataatctatt gcatatgata aaagttctat
    24061 tttttcttta tcattgaggt atcctaaatt tattaaaaca tctttctgtt tttttaaatc
    24121 ttgattatgc tcaaaaatgc ttttattaga ttttgcttta tattttttaa gaagttcctc
    24181 atctaacatc tatatcccac ccctcaatct taatatattc ttttataagg taattagcta
    24241 ggaaatttta tttttcctag ctaataatat aatttaatta aagaaaatta accaaaatct
    24301 cttgtttttt atcttgactc aatatttcta aataatctaa ctttacattc tcactactat
    24361 ttttagctcc tataaaatta ctatatataa ctggaacttt tttaaatatt cttctgtttt
    24421 tttcaagttt ataattttta tctaagtaat attttgttcc acctgcttga tgatcttgat
    24481 caactgctaa aggaattatt tttttatcac tcacatcttc attttttaag tacatagaaa
    24541 attttgaaac ccttatattt cttgaaaatt cttgcaactc aaccatttta cattcaacga
    24601 cttcaacaaa gtcctcactt cttcctagtg attgcaagtt gtaaatattt tcttctatat
    24661 cttttaaagt ttgtttatta gcttttatat gtaa
//
