LOCUS       NC_006138.1            24151 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_006138.1 Desulfotalea psychrophila LSv54, complete sequence.
ACCESSION   NC_006138
VERSION     NC_006138.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:29:22
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 262267
            Orig. end    :: 286418
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24151
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[272267:276418]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14151
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..24151
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24151
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             2414..5455
                     /locus_tag="ctg1_245"
                     /transl_table=11
                     /translation="MRKTKLYLALASLMLATPAHSYETITVGNFEAQLLAPGESAYAIG
                     AQTSEGAYTEVGDRRIITGTEAWTEGHRDAISRSLQALEQSFAMGSPKRKMQIAFALKK
                     GKEANLGDSLGTLIYDQYLTKIISTGELLLRDNSPTDKILGSVDDTINIYTSTPLHYGP
                     DAPGHDQYDFQSTVTHEILHAMGIMNGNDTDGSYPNGITRWDSLLEDGKGGHPTPENSP
                     SMTTTGKLGTVFWTGAAAKATYGGPVPIQTFADGYKEGSSLGHPGPAGELMTYQSDYLE
                     FPRAPNKLLLDMFRDMGWKINEAYYNSFGPTYYSNNSRISNTNNFETSHSYTYGMYVNG
                     NYNLIEQSGNLKTTKEYSNTLHIYGDKNIIRVSGKQSAEANYSHALYAFGRYNQIFIER
                     EGALAARGDGSVGILLFGADNTIFHSGTIKARDGATAIRIDNPFAHQAQGGHVLNASLH
                     IQTGSEIVGNIINSASGMADMTFGSNYASDGISSSPDPDFNFSYNDEIRGNWHHTITAG
                     KLNLGASAIIEGNMVNYGTLAGNGTIIGDVDSAGIIAPGNSIGKLTINGNLSQTSSSDL
                     QIEFGDGGYDQLVVSGTAHLDGALSLIPIGYLAPGTHQFINAGALAGNFATVNNFSSSI
                     LQTSAASLNPSNFTLTRRSYASVSESQQQSLASAFDRARPTASGDMADTLNLMDLMDLT
                     DIRQAADDFSPYFYNSVTTAILENIRTRSTFLQNKIRGDEADRQSPLWFSGYGGTTQYD
                     KTITSNDFKTKYAGFMLGFDRQFASGFQLGAAGAFTDFSLKEKATTSKARGSVYDGYLY
                     GSWSPQANDAFYLQSTLGIGLTDSKTNRNIPFLDRTATSDHDAIHYSAFLGGGYKQQIG
                     NWSLEPRAGFEYINLDEDGCTEYGAGAASLAVNSKDSDALVSSLGVEISHTFDLNNGLL
                     VPSFRADWFHNFSAEGEDTIATLQSGETFSVDGRTASENALELALGLRVLVSDKLHAYL
                     EYQYTFADHQNGAHLLSTGLSYYF"
     CDS             complement(5871..6464)
                     /locus_tag="ctg1_246"
                     /transl_table=11
                     /translation="MKTENKIISLAILMGLFICAGHVMVDYLLFNKGSFIEFLATDISK
                     GEIFIRILVLVCFVLFGLVSSRLITKQKAAEQKLAASLYFQQQLLDRIPVPIFYKDEEC
                     IYVGCNKSYEDFMDMPRKEIIGKSVYDIAPANLANIYHKKDSDLINKPGTQIYEFEVKS
                     KTHASNRQVILPQGNLRENRWTGYRPGRGNPGCY"
     CDS             complement(6861..7646)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_247"
                     /sec_met_domain="Fer4 (E-value: 3.6e-06, bitscore: 24.2,
                     seeds: 528, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHHTDSTHLIYFSPTNTSKSIGYSIAEELAGPAFHRHDLTFATAE
                     EALPATALAIIVVPVYAGRIAPLARKRLEAIRGAGTPAVLVVVYGNRDFEDALLELQDL
                     AQSQGFVPLAAAAFIGEHSYSTSNTPIGAGRPDEADLLAAKEFGREVAERLAHSGDSAL
                     QVPGNAEYRQGVGPVDYTPQVDSTLCNFCETCTSVCPAGIISAVEGKILFEAGDCIRCC
                     ACIKSCPTSAISFAVPALAELALKLHNNCRTRKEPRLFF"
     CDS             complement(7811..8881)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 57.8; E-value:
                     2.5e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_248"
                     /sec_met_domain="AMP-binding (E-value: 1.3e-16, bitscore:
                     57.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDSVKIDGKIYDAESLTSLLKSEAFLDLPLWRQNIFTFLAAWWQS
                     AESIEQYTSGSTGKAKPIQLAKRAMLASARRTCAFFHISEVSRLALCLSAEYIAGKMML
                     IRALVSGAELLTIAPEGNPHRKFSDDIDFVAMVPLQAENMLRDIGYTVRVKTVLLGGAE
                     VSAPLRELILACPETEFYLGYGMTETCSHVALQKIGVDDIYRGLPGVEFACDERGCLVV
                     EDGEVVGQALISNDMAALCAGGFRWLGRWDNIINSGGIKFSPEELESRIVHLLDYPFLL
                     TSSPDSRLGRKIILVIESADIYYLSRSKQDLFRKKMCLMLAEVLDKYALPRQIIYVSQL
                     VRTASGKVDRRFIYSL"
     CDS             complement(8893..9990)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_249"
                     /sec_met_domain="MR_MLE_C (E-value: 1.5e-24, bitscore:
                     84.3, seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELSYRRSDLIFKRPAGTSRGVLTSKPTWFVRLDIDGHGGQGEVS
                     LIPGLSLDPEEQIGRELDLLARRLRAEEPIRLRQFLAERGGADFSDYRSVLTDIAGILD
                     SWQVSTDGRFPALRFALEMALLDLLSGGRQEWFASDFTRGEKRIPVNGLIWMGEAAFMQ
                     EQIEAKLAEGYGCLKLKIGAIDFDKECALLAGIRESFSPQQLEIRVDANGAFSPANAPQ
                     RLKRLSQFHLHSIEQPIRQHQWSEMAALCANSPLAIALDEELIGLGAEQRSAMLDAIRP
                     QYIILKPSLLGGFHYAGQWIELARERGIGFWITSALESNLGLAAIAQWTALYQPTMPQG
                     LGTGQLYTNNLPSNLAVDGGLLGVS"
     CDS             complement(10001..10816)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_250"
                     /sec_met_domain="ECH_1 (E-value: 1.3e-81, bitscore: 271.2,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREWKTIKEYEEIKFEIFNGIAKITINRPRYYNAFTPDTNKEMLE
                     AMVYCRECQDVRVVIFTGAGDKAFCAGGDQNVKSTGGYIGKDGVPRLNVLDLQKAIRSL
                     PKPVIAMVNGFAIGGGHVLHVVCDLTIASENAKFGQTGPKVGSFDAGFGSSYLARQVGQ
                     KKAREIWFLCDQYSAQEAMDMGMVNKVVPLEQLEDTTVEWCEKIIKRSPMALRMIKAGL
                     NAELDGQAGIQELAGNATMMFYMMEEAQEGKNAFLEKREPDFDQFPKFP"
     CDS             complement(10970..12583)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_251"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.6e-07, bitscore:
                     27.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAKQHISDLAHHCIAHGMRHLVISPGSRNAPLIRAFAASSQIEC
                     LSIVDERSAAFVALGLATELQAPVGVLCTSGTALLNYGPAIAEAYYLRAPLIVLSADRP
                     ARLVGQQDSQTICQDNLFANIVKGSYSLPEEPETVAELELSARVIAQAFSTALSPCFGP
                     VHINIPLDEPLYGGELMAESLIALSPLQLAEPKGMSPALWQEVESAWRGAKRRMIVCGQ
                     GVADAELQALLARFAPDKTVTIIAENTANIVGPWLVDRPDAVLLACDEASRSLLAPDCL
                     ISFGGHLVAKHIKLLLREFKPAFHFRLDPAQMGIDTYQCLSAELDLAPTTFFRRLAQQV
                     EPAAGFRDLWALPEGVAENQDDEFLVLKRLLGQLPAGSIAHLGNSMSVRHAQKLASRAD
                     LLYHSNRGVAGIDGCLSTAVGVALATDQLVLCCLGDLSFVYDSNALWNRNLPSNLRIVI
                     LNNQGGDIFRRLKGPSVSPGYQDFFVAHHPVQIGKMIEAYGVAYRRCLASEIDGFSEEF
                     LGLQDGPLVLEVFVDPTKRD"
     CDS             complement(12657..13778)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_252"
                     /sec_met_domain="Chorismate_bind (E-value: 1.3e-54,
                     bitscore: 183.0, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPIKKTLPQLLQLCLDKKLCFASYREPGCDIVTLAQDGGEPLRL
                     SVDHEISEQRGFAIAPFVESDSCRPILISPDLISVGDAPDESLFARLEQFGGNSLNGCG
                     DIGETYQCDHAEYLQEVDSLVTAIEAGRFAKAVLSRVEIIRDDIREKVVATYIRMCARY
                     PHSLVYIFQADGHLWLGATPEILASVGQGKLQTIALAATRKNTPENQKFSAWSEKERQE
                     QQYVTDYINDLLISFDLKSVKRGLPYPRQAGNMLHLCTEFSCDSHEIGGKLSPLLQALH
                     PTPAVCGMPKEAARTFLHGLEKHDRQYYSGFLGPVNISPEQISLYVNLRCMQVCRGYAQ
                     VYVGGGITSDSVAEDEWTETVLKTKTILSALDN"
     CDS             complement(13792..14151)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_253"
                     /sec_met_domain="HBT (E-value: 8.4e-10, bitscore: 36.4,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQNLGIEFISYRNGVPRARMKVDSRTQQPHGYLHGGATIALAET
                     VASVASSCTDRDMAAFGYHVDASLLSSVREGYVYAEPLLVHRGRTSHIWDVRVETEMGK
                     TVALCRITVKLAAEA"
     CDS             14903..16063
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IspD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_254"
                     /sec_met_domain="IspD (E-value: 1.7e-71, bitscore: 238.0,
                     seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNGAVIIPAAGSGTRMKLDYPKQYHAVAGTPIIVHTIRAFNKHP
                     CIAKIILVVPQDHLEESKALLQKYQLENISIVTGGARRQDSVLRGLQEVPESIDIVLVH
                     DGARPMVSAELISRCYKGAQQYGAVIAAVPVKDTLKRGAGRIVTGTVDREGLWQAQTPQ
                     AARKALLVKAFKENGMRNVTDESTLLEGVGIPVTLIEGSETNIKITRPEDLILAENFLR
                     EKKEPMQKIRIGHGFDAHQLVEKRRLILGGVEIPYHLGLAGHSDADVLVHALCDALLGA
                     IGAGDIGRHFPDSSDAFKDIYSIRLLESVMQKVGELNYKIGNADISVICQAPKLAPYLK
                     QMQEIIATSCACQISDINIKATTTEKMGYTGRGEGISCHAVVLLQQ"
     CDS             16072..17211
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M20"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_255"
                     /sec_met_domain="Peptidase_M20 (E-value: 6.7e-20, bitscore:
                     69.2, seeds: 360, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNINSERVAQIFTALCEISSPSKNERVIANYLKEIFRELGATEIY
                     EDNSAEQTGSNSGNIIVRFAGSCPERTPLLFACHMDTVLPADNIEVARENDTFTSAGET
                     VLGGDDKSGIVALIEAFTLIKENDTEHGAIELVFTTCEEIGLLGAKYLEYDKLQAKMGY
                     ALDAGGSDTVVTRAPTANSIDIIIHGLAAHAGLSPAKGINALTLAAQALAGLQLGRLDA
                     DSTANFGLISGGTAVNIVPDKVCLHGEVRSQSPAKLDEYTEKICTVFRKTVADWSSPEH
                     KEQRPSIDIEVIKEYDAIVINEEGPLIQHLLRVTKAMGINIGITSTGGGSDANVFNGHG
                     IETAILATGMDLVHTTAERIDLKDMLKLTNLIYEIISQG"
     CDS             17232..18707
                     /locus_tag="ctg1_256"
                     /transl_table=11
                     /translation="MLLTKGDTVKENMSQVKTLSASQDYPTHECGVCGIFDHEDAAKLT
                     YFGLYALQHRGQESAGIVTSTGKEVFLHKDMGLVPEIFTEDILQGLKGDMSIGHVRYST
                     TGASNFTNTQPLMVHHKNQTLSVAHNGNLVNSTELRNRLEESGSIFQTTMDSEAVLHLM
                     VRNSGPDLDKTLSETFRALKGAYSLLYMTEDTLVAVRDPDGFRPLCLGRLTTGGWVIAS
                     ETCALDLIEADYVRDIEPGEVLIMKRGEEMRSIFPWPKQTPHHCIFEQVYFARPDSDVF
                     GINVYQSRKQMGKILAREAKIDADFVMPFPDSGNYAAIGYAQESGIPMEMGVIRNHYVG
                     RTFIEPSQSMRDFNVKVKLNPVRSLLKGKRVIIVEDSIIRGTTGKSRVRALREAGAKEI
                     HMVVSCPPTMHACYYGIDFPTSSQLIACNKNVEEIAEYLGLDSLHYLSLEGMVEATGIP
                     KEHYCLACFNGIYPIAPDQKYHKDALATKVVKG"
     CDS             complement(18744..19598)
                     /locus_tag="ctg1_257"
                     /transl_table=11
                     /translation="MIGKASFVLLLVVEEELLGKNLEELVRGYGYRVITAVDYAEALVA
                     TRSRRVDLLLVDHLPAGAEEEALIAMREVRRSIGLILVGADEENVYVAAVEGGALDFVA
                     EPVMARELELKIERARRESALRYRLSLIADFDEATGLEDGNAFFVHLSRELERAQRQKR
                     PMHLAMLYLQDVEKEQLAEIGLILKSSIRSYVDHACRCTKREFALLLPETNADQAAEIV
                     QRVLLQNLEKNFGEQPLAIGCVSCSIEKDEDLDDAEFRLIKKARMAMEESRAAGDYSVV
                     FRR"
     CDS             complement(19653..19859)
                     /locus_tag="ctg1_258"
                     /transl_table=11
                     /translation="MEQKVGEKLVAALKKRDDAESQESFVKAMELTKAYASSGSATHYS
                     AVTRLFYDLFEMFETGDDPRKKK"
     CDS             complement(19899..20225)
                     /locus_tag="ctg1_259"
                     /transl_table=11
                     /translation="MQAGKNCGENLSAIWYQYEVCPGAESLEAQRWKAGLVNMIVFAAS
                     DEEGRVLCGRYAARHDWQIIVLKRAGIISTEHLARMEGVFQALYRQAELSGIAARFDGW
                     QLSS"
     CDS             complement(20368..21384)
                     /locus_tag="ctg1_260"
                     /transl_table=11
                     /translation="MKAFVRSLCELIEQGEPCVLATVLESSGSTPRSSGAKMVVRAQHT
                     AIGTIGGGIVEAIACRDARRMLEDCKDGRAELTFTDMDQEMAANSDMICGGNLSVLLET
                     IESTGPCALAYRELDGLLRRGERAVLSTTFSKGDSLCSVGHEVMLGDYSALAGQAMEKE
                     SPCFSKSETELCFAEPFIPPAPLYIFGAGHVSLFTARVGAMLGFRTVVLDDRDDFANVE
                     RFPTVDEVRVLASFEDCCTDLSIPEDAYIIIVTRGHVHDLTVLGDALKTDARYIGMIGS
                     KKKRNAIYDALLADGVSQANIDRCHSPIGLTIGAQTPEEISVSIAAELIGVRAKTLL"
     CDS             complement(21388..22689)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_261"
                     /sec_met_domain="AMP-binding (E-value: 6.9e-09, bitscore:
                     32.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALSHLDRLLLRRMGMSEESSAPTAEEMSAWQLKYLQKTILHARE
                     KSPFYRRHFAGLELESLDSLQAFSALPRVTADDLRAGPEQFLCVSQDEIARAVTVQSSG
                     TTGAPKRIFYTESDLQATVDYFDAGMAHLVAAGQTAFLLMPTARPGGVGRLLVEGLERR
                     GVHIVSHGMVDEVAAAVDHLLQVDADCVIGPAAHLNLLACEWARRGLGHGQIASVLLCW
                     DAPSTAVVHNIERIWGCRAYRHWGMIETGLGGAVQCAPHSGMHLREADIFLEITDPETG
                     QPLPDGKFGELVLTTLQRWGMPLIRYRSGDLGRILADTCPCGSTSRRLDPWIRRLPQDS
                     SPLLTIDELNEALYSVAGLADFSASLAPGRLGILACGRGGSLESAIRVALKKIPTIFRA
                     IELGSLQISIEIKNDGRPAVPGLAKRCLQIDEER"
     CDS             complement(22670..24019)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_262"
                     /sec_met_domain="Radical_SAM (E-value: 1.2e-19, bitscore:
                     68.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSIARSVCPVCLKAIPAHHETIEGNTYLLKECPEHGAFKTVVWR
                     AGTSFKEWSRTKIPSQPKTPFTAVDRGCPYDCGLCAAHGQHTCTALLEVTWRCDLGCPV
                     CFASSGKKAAPDPSQAEISQLLERVELASGFCNIQLSGGEPTMRDDLAELIALAKKRGF
                     PFIQLNTNGLRIAREEGYAQRLAEAGLDSVFLQFDGTEDAIYSSLRGRPLMAEKRAAIE
                     ALSQAGIGIVLVPVVVPGLNDHNLGAILDLAVQNSPHVRGVHFQPVSYFGRYPQAPGDE
                     ERITLPELMDLLEVQSGGAVHAADFQPPGCEHSHCSFNGNYMVTEEGGLTKLSAGGKCD
                     CAPRPAREGADKAKSFVKRQWAGVKQSLPMAGALEDDLGRFISRAASHSLAISAMAFQD
                     AWTLDFERLRGCCIHVVSPDGRLIPFCAYNLTSMDGETLYRGKCNGPIPS"
ORIGIN
        1 caattataat cttattgacc agagtggtaa tttaaaaaca acgaaggagc aatcgaacgc
       61 cctatatgta tatggaaatg gaaacaaaat tagagtgaac ggcacacagt ctgccgatgc
      121 aaattactcc cacgcactct acgcttttgg tataaaaaac cagatattta tagaaggcga
      181 ggggactctg accgcaaaag gagctggttc tgttggtctt ttactttttg gttttgataa
      241 ctccattttt cactctggaa ctatcctggc gagtgatgaa gcaacagcta ttaggattga
      301 caatcatcgg gctacctggg gataccgcct gaatacatca ctgcacctcc aaaccggatc
      361 aaagatagtt ggggatatta ttaacactga ctctacgaag gcggcagata tgacctttgg
      421 tcgtaaatat gccagtgatg ggagctatag ccctgaccct aatttcaatt tttcctacaa
      481 tgatgagata cgaggggatt ggaattatga ctttcatagt ggtacggtaa catttgccaa
      541 tacactcaat cagcatgaag gtacaatatt aacaggtaat ggttcaatta ttggtgatgt
      601 tgatagcgcg ggtattatcg ccccgggtaa ttctattggc aaactaacaa ttaacggaaa
      661 tcttagccaa accagtagtt cggatttaca gatagaattt ggtgacggtg gctacgatca
      721 gcttgtggtg agcggtacag ctcatcttga cggctcactt tcattaatcc ccattggtta
      781 tcttactccg ggtacccatc aattcatcaa tgcaggtgcc cttgccggta actttgccac
      841 tgtaaataac ttttccagca gtatcctgca aacatcagct tccagtttca atcccagcaa
      901 ttttaatcta gtgcgcaata gttacgcatc agtaagtgaa agccagcagc aaagtctagc
      961 cagttctttt gatagagctc gaccgactgc aagcggagat atggcagata ctctcaatct
     1021 gatggatctg atgaatctta ccgatatcag gcaggcagca gacgattttt cgccttattt
     1081 ctacaactct gttaccacag caattttaga aaacatcaga acaagatcaa ctttcttgca
     1141 aaacaagata agaggagatg agacagatcg tcaatcgcca ctctggttct cgggctacgg
     1201 cggtactacc cagtacgaca agacagtcac cagcaacgat tttaaaacca aatattccgg
     1261 ttttatgctg ggctttgaca gacaatttgc atctggattt cagctaggag ccgcaggcgc
     1321 tttcactgat ttttctttca aggaaaaagc caccaccagc aaggcaaggg gttctgttta
     1381 tgatggctat ctttacggtt catggtcacc acaggcaaat aatgcgttct acctgcaatc
     1441 aactctaggc attggcctta ctgactctaa aaccaatcgg aatataccct ttctagatag
     1501 aacagccact agcgaccacg atgcaatcca ttactctgcc tttcttggcg gtggttacaa
     1561 acagcagata ggcaattggt ctcttgagcc acgggcaggg cttgagtaca tcaatcttga
     1621 tgaagacggc tgcacagaat atggagcagg agccgcctcc cttgctatca actcaaaaga
     1681 ttccgacgca ttggtaagtt ctcttggggt tgaaatcagt cgtactattg agctcaataa
     1741 tggctcgtta gtgccgagct ttcgagctga ttggttccat aatttttctg ccaagggaga
     1801 aaataccatc gccaccttgc aaagcggtga atctttcagt gttgatggtc gcacggcaag
     1861 cgaaaatgcc ctggaattag cccttggttt aagggtactg gtcagcaata agctacacgg
     1921 ttattttgaa tatcaataca cctttgccga caattaaagt ggagcccatt tactaagcac
     1981 aggactcagt tattattttt aagagacaga ccatgttcac ggcagagatc ggtttcagat
     2041 ctactatttt tctccatatt atcatattaa gtagatacta tggaaagaaa ggacaaacag
     2101 agatgcgccc gccggaactc tgttaagggc aagggtgggt agcggcgtca gtagcgtagc
     2161 ggcgagcaag cggaggcccc cctcctgacc tctcccgcaa aaaaaaatcc catattacac
     2221 gataaaataa gatatcatct tactaactgc tacgaaacgt tagaccctaa tgagcttcac
     2281 ccttgcccat gtgtccattt caagctcagg aaaatcaaac tgccgaagat ttttttgcca
     2341 ccatctattc aatatcgtgc agaccttaaa aaaataagcc tatagctaac aggctaaatt
     2401 atatgggatc ccaatgcgca aaacgaaatt atacctggcc cttgccagct taatgctggc
     2461 caccccagcc cactcctatg aaacaattac tgtcggaaat tttgaagctc aacttcttgc
     2521 ccctggagaa tcagcatacg ccataggagc acaaactagt gaaggtgctt atacagaggt
     2581 gggggacaga agaataataa caggaaccga agcgtggact gaggggcata gagatgctat
     2641 tagcagaagc ctgcaagcac tcgaacagag ttttgccatg ggtagcccaa aaagaaagat
     2701 gcagattgcc tttgctctaa agaaagggaa agaggcaaat ctcggggact cactcggcac
     2761 cctgatttac gatcaatatt tgacgaagat tatttcaaca ggagagttgc tcctgcgtga
     2821 caatagccct acagacaaga tcctgggtag tgtagacgat actatcaaca tatacacatc
     2881 tactcctcta cactacgggc ctgatgctcc tggccacgat caatatgact tccagtcaac
     2941 ggtaacccat gaaatacttc atgccatggg tattatgaat ggtaatgaca ccgatggcag
     3001 ctatccaaat ggcatcacaa gatgggattc attgttagaa gatggtaagg gtggacatcc
     3061 tactcccgag aatagcccct ctatgacgac taccggtaaa ctcggtactg tcttctggac
     3121 aggggcggct gccaaggcta cctatggagg ccctgtccct atccaaactt ttgcagatgg
     3181 atataaagaa ggtagttctc ttggccatcc aggtcctgct ggagagctga tgacttacca
     3241 gagcgattac ttagaattcc caagagctcc gaacaagctg ctgcttgata tgtttcgaga
     3301 tatggggtgg aagataaatg aggcgtacta caatagtttt ggtcccacct attacagcaa
     3361 taatagccgc ataagcaata cgaataactt cgaaacaagc catagctaca cctacggtat
     3421 gtatgttaat ggtaattata atcttattga gcaaagtggt aatttaaaaa caacgaagga
     3481 atattctaac accctacata tatatggaga taaaaacata atcagggtga gcggcaaaca
     3541 gtctgccgag gcaaattact ctcacgctct ttatgctttt ggtagatata accagatatt
     3601 tatagaaaga gagggggctc tggccgctag gggagatggc tctgttggta ttttactttt
     3661 tggtgctgat aacactattt ttcactctgg aactatcaag gcgagggatg gagcgacagc
     3721 cattaggatt gacaatcctt ttgctcacca ggcccaaggg ggacatgttc taaatgcatc
     3781 actgcatatt caaaccggct cagaaatagt tgggaatatt attaatagtg cctctggtat
     3841 ggcagatatg acctttggca gtaattatgc cagtgatggt attagctcta gccctgaccc
     3901 tgatttcaat ttttcctata atgatgagat acgagggaat tggcatcata ctattacggc
     3961 aggaaaatta aatttaggcg cttcggctat tatcgaaggc aatatggtga attatggtac
     4021 gctagctggt aatggcacca ttattggtga tgttgatagc gcgggtatta tcgccccggg
     4081 taattctatt ggcaaactaa caattaacgg aaatcttagc caaaccagta gctctgattt
     4141 acaaatagaa tttggtgacg gtggctacga tcagcttgtg gtgagcggta cagctcatct
     4201 tgacggcgca ctttcattaa tccccattgg ttacctggcc cccggtaccc atcaattcat
     4261 caacgcaggc gcccttgccg gtaactttgc cactgtaaat aacttttcca gcagtatcct
     4321 gcaaacctct gctgccagtt taaatcccag caatttcacc ctaacgcgca ggagttacgc
     4381 atcggtaagt gaaagccagc agcaaagtct agccagtgct tttgatagag ctcgaccgac
     4441 tgcaagcgga gatatggcag atactctcaa tctgatggat ctgatggatc ttaccgatat
     4501 caggcaggca gcagacgatt tttcacctta tttttacaac tctgttacca cagcaatttt
     4561 agaaaacatc agaacaagat caactttctt gcaaaacaag ataagaggag atgaagcaga
     4621 tcgtcaatcg ccactctggt tctcgggcta cggcggtact actcagtacg acaagacaat
     4681 taccagcaac gattttaaaa caaaatatgc cggttttatg ctgggctttg acagacaatt
     4741 tgcatctgga tttcagctag gagccgcagg cgctttcact gatttttctc tgaaggaaaa
     4801 agccaccacc agcaaggcaa ggggttctgt ttatgatggc tatctttacg gttcatggtc
     4861 accacaggca aatgatgcgt tctacctgca atcaactcta ggcattggcc ttactgactc
     4921 taaaaccaat cgcaatatac cctttctaga tagaacagcc actagcgacc acgatgcaat
     4981 ccattactct gcctttcttg gcggtggtta caaacagcag ataggcaatt ggtctcttga
     5041 gccacgggca gggtttgagt acatcaatct tgatgaagac ggctgcacag aatatggagc
     5101 aggagccgcc tcccttgctg ttaactcaaa agattccgat gcattggtaa gttctcttgg
     5161 ggttgaaatt agtcacacct ttgatctcaa taatggctta ttagtgccga gctttcgagc
     5221 tgattggttc cataattttt ctgcagaggg agaagacacc attgccacct tgcaaagcgg
     5281 tgaaactttt agtgttgatg gtcgcacagc aagcgaaaat gccctggaat tagcccttgg
     5341 tttaagggta ctggtcagcg ataaactaca cgcttatctc gaatatcaat atacctttgc
     5401 cgaccatcaa aatggagccc atttactgag tacaggactg agttattatt tttaagggat
     5461 gtttacggca aagttcggcc atagagacac caccttcagc gacgggaaat agcaacagcg
     5521 gagcggcgaa gggaaagtta gaaggaaaaa gcggagtgac ggcaggggtg caagtgactg
     5581 acgtagctca cctccccctc aaccccgtcc cggcacctta gagaatgggt ggctcctggc
     5641 aaaactcagg atatagcttt tttgcacact ccggacagat accatgactg aattctgcct
     5701 ctgaatgatc ccttatgtat gactcaattt cactccagta acccctgtca tctctaatat
     5761 tcttgcatga cgcacagatg ggcaggaaac cactgagttg ctttacctta tcaagggcca
     5821 attgcagttc tgtaatcaat ctctcgcttt cagcttctgc attttttatt tcagtaacat
     5881 ccaggattgc ccctaccagg cctgtaacct gtccatctgt tctctcgaag gttgccttgt
     5941 ggcaatataa cctgacgatt actggcatga gttttacttt taacttcaaa ttcataaatt
     6001 tgagttccgg gcttattgat aagatcggaa tcttttttat gataaatgtt ggcaagattg
     6061 gcaggggcaa tatcatagac agactttcct atgatctctt ttctgggcat atccatgaaa
     6121 tcttcataac tcttattaca tcctacgtaa atgcactctt catctttgta aaaaattggc
     6181 acagggattc tgtctaaaag ttgctgctgg aagtagagtg atgctgccag cttttgttcc
     6241 gcggctttct gtttcgtgat tagcctggaa ctgactagac cgaacagaac aaaacatacc
     6301 agaaccaata tcctgataaa tatttcacct ttcgaaatat ctgtcgctaa gaactcaata
     6361 aatgaccctt tattaaatag caaatagtcc accatgacgt gacctgcaca gataaaaaga
     6421 cccatgagaa tagccaatga gatgatcttg ttttcagtct tcatagctag ccttctcctt
     6481 ttataaaaac agggtattgc tcgtgcgtag acattatgat ctcttctttt tattgtagaa
     6541 atattttctt agccactcgc atgcaaaact gctcaaacca gaattaattt tatatggctc
     6601 atcattatcc ccacttcttg aagtgatacc ctatcggttt aacaggaaca agatgaacct
     6661 gcaaagggtt tccctctcag atatcaaact tttgcagtaa ggcagcttgt aggggggagg
     6721 gattttgctc cgttacacgg gcaaggatgg atagcagcga cgaaccccct tcacctcccc
     6781 cttttctcct cccccttatt ttcaaggggg aggtcgggag ggggttgaag ggggaggtaa
     6841 aggggggagg aggagagtgc ctagaagaag agccgaggtt ccttgcgagt gcggcagtta
     6901 ttatgcagct tcaaagccag ttcggcaaga gccggaacgg caaaggagat ggcggacgtc
     6961 gggcagctct taatgcaggc acagcaacgg atacagtcac cggcctcaaa gagtatcttg
     7021 ccctcgacag cactgatgat ccctgcagga cagaccgagg tacaggtctc acaaaagtta
     7081 cagagagttg aatcgacctg cggagtatag tccaccggtc caacgccctg tcgatattcc
     7141 gcattgccgg gcacctggag ggctgaatca ccactatggg caagtctctc tgctacctct
     7201 cgaccaaact ctttggcggc gaggagatct gcctcatccg gtctaccggc accgatgggg
     7261 gtattgctgg tggagtagga gtgttcgccg ataaaggcgg cggcagctaa ggggacaaag
     7321 ccctgagact gggccagatc ctgcaactct agaagggcat cctcaaaatc acgattaccg
     7381 tagaccacca ccagaacggc aggggttcct gccccccgaa ttgcctccag acgcttacgg
     7441 gccaggggtg ctattcgtcc ggcatagacg ggaacaacta taatggccag ggcagtggca
     7501 ggtagtgcct cttctgccgt ggcaaaggta aggtcatgcc tgtggaaggc tggaccggca
     7561 agctcttcgg caatactata gccgatgctc tttgaggtat ttgtggggga aaaatatatg
     7621 agatgggtac tgtctgtatg atgcatcgtg tcaccttttg aaaaacgtga aagctactca
     7681 gccacagcac tcgaaaaggg tactgcggat ataatacagg gtgtaattat taagactgtt
     7741 ggaaggcctc aacgacaaaa caccccttgg taaaagcccc ttaaaggagt tcaagaccag
     7801 tagaacaagc ctagaggcta taaataaagc gtctgtccac cttgccactg gccgtcctga
     7861 ccagttggga gacatagatg atctgccggg gcagggcata tttatccagt acctccgcaa
     7921 gcatgagaca catctttttt cggaagagat cctgtttgga tctgctcaga taatagatat
     7981 cggccgactc tatgaccaga ataatcttcc ggcccagacg actgtcagga cttgaggtca
     8041 gcaaaaatgg atagtcaagc agatggacaa tgcggctctc aagctcttcc ggggaaaatt
     8101 taattccgcc tgagttaatg atattatccc agcgccccaa ccagcgaaag cctccggcac
     8161 aaagcgctgc catatcgtta ctgatcagag cttggcctac cacctcacca tcctccacca
     8221 ccagacagcc acgctcatca caggcgaact ccacccccgg caggcctcga taaatatcat
     8281 cgacaccaat tttttgcagg gccacatggg agcaggtctc tgtcatgcca tagcccagat
     8341 aaaactccgt ctccgggcag gccaaaatca actcccgcag gggggctgaa acctcggccc
     8401 cgccgaggag aacagtcttc acccggacag tatagccaat atcccgcagc atattttccg
     8461 cctgaagggg aaccatggcc acaaagtcaa tatcgtcact aaattttcgg tggggattgc
     8521 cctcgggggc gatggtcaga agctcggccc cggagaccag ggccctaata agcatcatct
     8581 taccggcaat atattccgcc gagagacaga gggccagtcg actgacctcc gagatatgaa
     8641 aaaaagcaca ggtccgacgg gcagaggcca acatggccct cttggcaagc tgaataggct
     8701 tggcctttcc ggtggagcca gaggtatact gctctatact ctccgcagac tgccaccagg
     8761 cagccaaaaa ggtgaaaata ttctgccgcc agaggggcag atcgaggaag gcctcgctct
     8821 taagcaggga ggtaagagat tcagcatcat agatctttcc atcaatttta acagagtcca
     8881 tcggcagatc ctttaagata cccccaaaag tcccccgtcc acggcaaggt ttgagggaag
     8941 attattggta tatagctggc ctgtccccag cccttggggc atggtgggct gatagagggc
     9001 cgtccactgg gcaatggcgg caagccccag attagattca agggccgaag tgatccagaa
     9061 accgatacca cgctctcgag caagctctat ccactgtccg gcatagtgaa agccaccaag
     9121 cagggatggt ttgagaatga tatactgggg cctgatggca tcgagcatgg cagaacgctg
     9181 ttcagcccct agcccgatca gctcctcatc cagagcaatg gccagaggag agttggcaca
     9241 gagagccgcc atctcggacc attgatgctg gcgaatgggc tgctcaatgg agtgaagatg
     9301 gaactgactg agacgcttca gtctttgtgg ggcattggca ggcgaaaagg caccgttggc
     9361 atcgacccga atctccagct gctgcggaga aaagctctca cgaatgccgg cgagaagggc
     9421 acactcttta tcgaaatcaa tggccccaat cttcaatttc agacagccat agccctcggc
     9481 cagcttggcc tcgatctgtt cctgcataaa agcggcctcg cccatccaga tcaggccatt
     9541 gaccggaatc cgcttttcac cacgagtaaa gtccgaggcg aaccactcct gcctgcctcc
     9601 agagagcaga tccagcaggg ccatctccag ggcaaagcgc agggcaggaa agcgaccatc
     9661 ggttgagacc tgccaggaat ccaaaattcc ggcaatatcg gtcagaacag acctgtagtc
     9721 agaaaaatcc gccccccccc tctcagccag aaactggcgg agacgaattg gctcctcggc
     9781 ccgaagtctc cgggcaagga gatcaagctc tcgccctatc tgctcctcgg gatcaagaga
     9841 gagtcccgga ataagggata cctccccctg ccctccgtga ccgtcaatat ccagacggac
     9901 aaaccaggtg ggcttactgg tgagcactcc acgggaggtg cccgccggtc gcttaaatat
     9961 cagatcactg cgtctatagc tcagttccat gccagacacc ttatgggaat ttaggaaact
    10021 gatcgaaatc cggctcgcgt ttttccagga aagcgttctt gccctcctga gcctcttcca
    10081 tcatatagaa catcatggtg gcattaccgg caagctcctg gataccggcc tgaccgtcaa
    10141 gctcagcatt aagacccgcc ttgatcatgc gcagggccat ggggctccgt ttgataatct
    10201 tttcacacca ctcaacggtg gtatcttcca gctgttccag aggaacaacc ttattaacca
    10261 tccccatatc cattgcctcc tgagcagagt actgatcaca gagaaaccag atttcccggg
    10321 ccttcttctg gccaacctga cgggcaagat aggaggaacc aaagcctgca tcaaaactgc
    10381 ccaccttggg tcctgtctga ccgaatttgg cattttccga ggcaatggtc aaatcgcaaa
    10441 ccacatggag gacatggcca ccgccaatgg caaaaccatt taccatggca ataacgggct
    10501 tgggcaggga acggatggcc ttttgcagat cgaggacatt aagacggggc actccgtcct
    10561 taccgatata accaccggtg ctcttcacat tctgatcacc acccgcacag aaggccttat
    10621 cgcctgcacc agtaaagatc accacccgca cgtcctgaca ctcacggcaa tagaccatgg
    10681 cttcaagcat ctctttattg gtatcggggg taaaggcgtt ataataacga ggacgattaa
    10741 tggttatctt ggcgatacca ttaaaaatct caaacttaat ctcttcatac tcttttattg
    10801 ttttccattc tctcatggct gtttccttcg ttatattata gggggtaaaa ttaatgggaa
    10861 tcttaaaaaa ttaatatttt ccataagggg cacatggaaa attttaccac aggcatcgtt
    10921 aataccgaag tctacgctga gcttcgataa tagccttttt caaagttccc taatctcttt
    10981 tggtcggatc aacaaacacc tcaagaacca gagggccatc ctgcagtcct aagaattcct
    11041 cggaaaaacc atctatctcc gaggccaggc aacggcgata ggccacgcca tatgcctcta
    11101 tcatcttacc tatctgcaca ggatgatgag cgacaaaaaa gtcctgatag ccgggactga
    11161 cactgggccc cttcagcctt ctaaaaatat caccaccctg attattgaga ataacaatac
    11221 gcaggttgga aggcagattg cggttccaga gggcattgga gtcatagaca aagctcagat
    11281 cacccaaaca acagaggacc agctgatccg ttgccagggc aacccccacg gcggtggaga
    11341 gacagccatc aatgcccgcc acccctcgat tgctatgata gagaagatca gctctggagg
    11401 ccagtttttg ggcatgacgc acggacatgg agttgcccag atgggcaata ctacctgcgg
    11461 gcagttggcc cagcagtctc ttcagaacca gaaactcatc atcttggttc tcagcaactc
    11521 cctcgggcag agcccagaga tcacgaaaac cggcagctgg ctccacctgc tgagcaagac
    11581 ggcgaaaaaa tgttgtgggg gcaagatcaa gttctgcact gaggcactga taggtatcaa
    11641 tacccatctg ggcaggatcg aggcgaaagt gaaaggccgg tttaaactcc cgcaggagga
    11701 gcttgatgtg ctttgcaacc agatgaccgc caaaggagat aagacagtca ggggccagaa
    11761 gagatctgga tgcctcatca caggccagaa gcacggcatc tggtctgtcc accagccagg
    11821 ggccgacgat attggccgtg ttttcggcaa taatggtcac agttttgtcc ggagcaaatc
    11881 gagccaaaag ggcctgaagc tcagcatcgg ccacgccctg tccacataca atcatccgcc
    11941 gcttggcacc tcgccaggca gactccacct cctgccagag agctggactc atacccttgg
    12001 gctctgctag ctgcagagga gaaagagcaa taagggactc agccatcaat tcgcctccat
    12061 agaggggttc atcgagggga atattgatat gaacggggcc aaagcaggga gagagggcgg
    12121 tagaaaaggc ctgagctatg actcgcgccg acagttccag ctccgccaca gtttccggtt
    12181 cttcaggcag gctataacta cccttaacaa tattggcaaa gaggttatcc tggcaaatgg
    12241 tctgactatc ctgctgacca accagacggg ccggacgatc ggctgaaaga actataaggg
    12301 gggcccgcag atagtaggcc tcggcaatag ccggtccata gttgagcaga gccgtccccg
    12361 aggtacagag cactcccacc ggggcctgta gttccgttgc cagaccgagg gccacaaagg
    12421 ccgctgatcg ttcatcgaca atgctcaggc actctatctg ggatgaagca gcaaaggcac
    12481 ggataagggg ggcgttacgg gaaccaggag aaatcaccaa atggcgcatg ccatgggcga
    12541 tacagtgatg agcaaggtct gaaatatgtt gttttgcacg catattatct attgtatgag
    12601 gcttccggcc attggccggg gtcagtaagg cagaccctgc acagactgac aggaatttaa
    12661 ttatccaggg cggagagaat agtcttggtc ttcagtacag tttccgtcca ctcatcctcg
    12721 gcaacagagt ccgaagtgat gccaccaccg acatatacct gagcataacc tctgcatacc
    12781 tgcatacagc gcagattcac ataaagagaa atctgttccg gagatatatt taccggcccc
    12841 agaaagcccg agtagtactg gcgatcgtgt ttctccaaac catggaggaa ggtacgggcc
    12901 gcctccttgg gcataccaca taccgccggg gtgggatgga gggcctgaag cagcgggctt
    12961 agcttaccac ctatctcatg tgaatcacag gaaaattctg tgcatagatg gagcatattg
    13021 ccagcctgac gtggataggg caggcccctc ttaaccgact tcagatcaaa gctaatgaga
    13081 agatcattta tataatcggt gacatactgt tgttcctgtc tctctttctc tgaccaggca
    13141 gaaaattttt ggttttcggg agtgtttttt cgagtggccg caagagcgat ggtttgcaac
    13201 ttcccctgcc cgaccgaagc cagaatctcc ggagtggctc ccaaccagag atgcccatcc
    13261 gcctgaaaga tatagacgag ggagtgggga taacgagcac acattcttat ataggtggcc
    13321 accacctttt cccgaatatc gtccctaata atctccaccc gagagagtac ggccttggca
    13381 aaccgacccg cctcgatggc cgtaaccaga ctgtccacct cctgcagata ctccgcatgg
    13441 tcacactgat aggtctcacc aatgtctccg caaccattaa gcgaattacc accaaactgc
    13501 tccagtctgg caaaaagaga ctcatctgga gcatcaccta ctgagatcag atccggggag
    13561 ataaggatgg gacggcagga atcgctctcg acaaaggggg caatggcaaa gcccctctgc
    13621 tcagatattt catgatcaac actgagcctc aggggctctc cgccatcctg ggccagggta
    13681 acaatatcac agcccggctc tcgataagag gcaaagcaga gttttttatc cagacagagc
    13741 tgaagcagtt gaggcagggt tttctttata ggtttcatgg ggtcaaccag actatgcctc
    13801 agccgcaagc tttacggtga tacgacagag ggcaacggtc ttacccatct ctgtctccac
    13861 ccgcacatcc cagatatgac tagtccggcc cctatggaca agcaggggct cggcgtagac
    13921 atagccctca cgcaccgatg agagaagaga ggcatcaaca tgataaccaa aggccgccat
    13981 atctctgtct gtacaggaag aggcgacact ggcaacggtc tcggccaggg caatggtagc
    14041 gcctccatgc agatagccat ggggttgttg ggtgcggcta tcgaccttca tccgcgctcg
    14101 ggggacacca tttctatatg agatgaattc aatacccaga ttctggatca ttgaatcctt
    14161 acaaatttta tttatttcgt ctaaagtcat aaatatagag accacattcc aggcaataaa
    14221 cttcaccaaa atagtacgtt aaatagagcg ttcaagatgc ccagactgta gtccctcccc
    14281 cgttctatgg caagtttttt ctttaaggag atgtcttgcc gaaaaaggcc ctgcaaaaag
    14341 aaaacccact ttttctccgc ctaagaaaag ggccaggact aaacagctcg cccataaaag
    14401 ggcctcgcct cctccaggaa taatctcttc tcctctcctt atcgcaaaaa agtctttcat
    14461 cttttcctgt ttccaactat aagaaagctg tgtgtgaagt gggctcatga tcgccccgac
    14521 tttcgcagtc ggagaggaaa gtccgaactc cgcagggcaa gatggttcgt aacacgaaca
    14581 ctgggtgacc ggtggaaagt gccacagaaa atagaccgcc tggttcgcca ggtaagggtg
    14641 aaacggcgag gtaagagctc accgctttca cggtgacgtg gaaggcaggg caaaccccat
    14701 ctggagcaag accaaataga gagatgtttg agggcggctc cgtccgagat ctccgggtag
    14761 gttgcaagag gcgtcgggca accgacgtcc cagtgaaatg atcatggctc ccttcgggga
    14821 gagacagaat tcggcttata gcccacttcg cacatttttt ttcgtctcaa aacaaggaaa
    14881 catctcaccg caagacagga aaatgaaaaa cggtgcagtc atcatacccg cagcaggtag
    14941 cggcacacgg atgaaactgg attaccccaa acagtatcat gctgttgcgg ggactcccat
    15001 tatcgttcac accatacgcg cgttcaataa acacccctgc atagcaaaaa taatccttgt
    15061 cgtcccccaa gatcatctcg aagaaagcaa agctctcctg caaaaatatc agctagaaaa
    15121 catctcgatt gtgactggcg gcgcccgtcg tcaagactcc gtactccgtg gtctacaaga
    15181 ggttccagag tcaatagata ttgttttggt gcacgatggg gcccgcccca tggtcagtgc
    15241 cgagctcatc agccgttgct ataaaggcgc ccagcaatac ggggctgtca ttgccgctgt
    15301 gccggtaaaa gacaccctga agaggggcgc aggcagaatt gtgactggca ccgttgaccg
    15361 cgagggacta tggcaggccc agactcccca agctgcccga aaagctcttc tcgtcaaagc
    15421 ctttaaggaa aacggcatga gaaatgtcac cgatgagtcc acccttctgg aaggggtagg
    15481 aatccccgta accctgatcg agggatcaga gaccaatatc aagattaccc gccctgaaga
    15541 cctcatccta gctgaaaact tcctcagaga aaaaaaagaa cccatgcaaa aaatacgcat
    15601 tggccacggc tttgatgccc accagctggt cgaaaagaga aggttgatac tgggcggagt
    15661 agagatcccc taccacctgg gccttgccgg ccattccgac gccgacgttc ttgtccatgc
    15721 cctctgtgat gccctgctcg gagccattgg cgcaggtgat atcggccgcc atttccccga
    15781 cagcagtgat gcctttaagg atatctattc catcagactc ctcgaatcgg tcatgcaaaa
    15841 ggtaggggag ctgaactaca aaatcggcaa cgccgacatc agcgtgatct gccaggcacc
    15901 aaagcttgcg ccctatctca agcaaatgca ggagatcatc gccaccagct gtgcctgcca
    15961 aatcagcgat atcaatatca aggccaccac caccgaaaag atggggtata caggccgggg
    16021 cgaaggtatc agttgccatg ccgtcgtcct tcttcaacaa taaggtagac catgaatata
    16081 aacagcgaaa gagttgccca gatatttacc gcactgtgcg agatcagctc accttcaaaa
    16141 aacgaaaggg taattgccaa ctatcttaag gagatcttca gagagctggg tgccacggaa
    16201 atttacgagg ataattccgc cgaacagacc ggctccaaca gcggcaatat cattgttcgc
    16261 tttgccggat cctgccccga acgcaccccc ctcctctttg cctgtcatat ggacactgtc
    16321 ctgccggcag ataatatcga ggttgcccga gagaacgaca ccttcaccag cgccggcgaa
    16381 actgtgctcg gcggtgacga taagtcagga atcgtggccc tgatagaggc attcaccctg
    16441 atcaaagaaa atgacaccga acacggagcc attgaactgg tctttaccac ctgcgaagag
    16501 atcggcctgc tcggagccaa gtaccttgag tacgacaaac tccaggcaaa gatgggctat
    16561 gcccttgatg ccggtggtag tgacaccgtt gtcacccggg ccccgacagc aaacagcatt
    16621 gatataatca tccacggact ggcagcccat gccggcctca gcccggcaaa ggggatcaat
    16681 gccctcactc ttgccgccca ggccttggca ggcctgcagc tgggacgact ggacgcggat
    16741 tcaaccgcca acttcggcct tatctccggt ggtacggcag tcaacattgt ccccgacaag
    16801 gtctgtctcc atggcgaggt gcgcagccaa tcaccagcca agctcgatga gtatacggaa
    16861 aaaatctgca ctgtctttcg taagaccgtg gccgactgga gtagccctga gcataaggag
    16921 cagagaccct ctattgatat agaggtgata aaagagtacg acgccatcgt cataaacgaa
    16981 gagggaccgc tcatccagca cctcctccgg gttaccaagg ccatgggtat aaatatagga
    17041 atcacctcca ccggaggcgg cagtgatgcc aatgttttta acggccacgg tatagagacg
    17101 gctatcctgg caacgggcat ggatctagtc cataccaccg cagaacgaat cgatcttaaa
    17161 gatatgctta aattgacgaa tcttatttat gaaatcatca gtcagggata gtatttaatc
    17221 caccctcatc tatgctgctt acaaagggcg acacagtaaa ggaaaacatg tcacaggtaa
    17281 aaacattatc cgcgtcccag gactacccca cccacgaatg tggtgtttgc ggtattttcg
    17341 accatgaaga tgctgcaaag ctcacctact tcggcctcta tgccctccag caccgtggcc
    17401 aagaaagtgc gggaattgtt acatcaaccg gcaaagaggt ctttcttcac aaagatatgg
    17461 gacttgtgcc cgagatcttt accgaagata tcctgcaagg acttaaaggg gacatgtcca
    17521 tcggccatgt acgctactcc accaccggtg cgtccaactt caccaatacc caacccctga
    17581 tggttcacca taagaaccag accctctccg ttgcccacaa tggcaacctg gtgaactcca
    17641 ccgagctcag aaacaggctc gaggagagtg gttctatctt tcaaaccacc atggactccg
    17701 aggccgtcct ccatctcatg gtacgcaaca gcggtcccga tctcgataaa acactgagcg
    17761 agacattccg tgccctcaag ggtgcctatt ccctgctcta tatgaccgag gacaccctcg
    17821 ttgccgtccg tgatcccgat ggatttcgcc ccctctgcct tggtcgcctg accactggcg
    17881 gctgggttat agcctctgaa acctgcgccc tcgacctcat cgaggccgat tatgtacgtg
    17941 atatcgagcc gggtgaagtt cttatcatga aaagaggtga ggagatgcgc tccatcttcc
    18001 catggccaaa acagaccccg caccactgca tctttgagca ggtctacttt gcccgtcccg
    18061 attccgatgt ctttggtatc aacgtctatc aatcacgtaa gcagatgggt aagatcctgg
    18121 cccgcgaggc aaagattgat gccgatttcg ttatgccctt tcctgattcc ggtaactatg
    18181 cggccattgg ctatgcacag gaatccggta ttcccatgga gatgggcgtg atcagaaatc
    18241 actatgtggg caggacattc attgaaccaa gccagtccat gcgtgacttc aacgtcaagg
    18301 tcaagctcaa ccccgtacga tctctcttga agggaaaacg ggttatcatc gttgaggatt
    18361 ctattatccg aggaacaaca ggtaagagtc gggtacgagc cctacgcgag gcgggggcca
    18421 aagagatcca catggtggtc agctgtcctc cgaccatgca tgcctgctac tatggcatcg
    18481 atttcccaac ctcatcacag ctcattgcct gcaataagaa cgtcgaagaa atcgcagaat
    18541 atctgggcct ggactctctc cactacctca gccttgaggg catggtagag gcaacgggta
    18601 tccctaaaga gcactactgt ctggcctgtt tcaatggcat ttaccccatc gcccctgatc
    18661 aaaaatatca caaagacgct ctggcaacaa aggttgtcaa gggctagaat aaatacagta
    18721 cagggggatg ccccctgtac tgcttatctg cgaaaaacca ccgaatagtc acctgcagca
    18781 cgagactcct ccatggccat tcttgccttt ttgatcaacc taaactcggc atcatctaag
    18841 tcctcgtcct tctcaatgga acaggaaacg catcctatcg ccaggggctg ctcaccaaaa
    18901 ttcttctcaa gattctgcaa gagaacccgt tggacgatct ctgcggcctg atcggcattg
    18961 gtttccggca ggagaagggc aaattcacgc tttgtgcaac gacaggcatg atccacatag
    19021 gaacggatag aagactttaa aatcaagcca atctcggcaa gttgttcctt ctccacatcc
    19081 tgcaaataga gcatggccag atgcatggga cgtttttgcc gctgggcacg ttcgagttca
    19141 cgggagagat ggacaaagaa ggcgttacca tcctcaagcc ccgtggcctc atcaaaatca
    19201 gctatgagcg agagtctgta gcgcagagca gattcccgcc tggcccgctc aattttaagc
    19261 tccagctctc ttgccataac cggctcagca acaaaatcca gggcacctcc ctcaacggca
    19321 gccacataga cattctcctc gtccgccccc accagaatga ggccaatgct acgccttacc
    19381 tccctcatgg caataagcgc ctcctcctct gctcctgcgg gcagatgatc caccaaaagg
    19441 agatcaaccc ttctactacg ggtcgcaacc aatgcctcgg catagtcaac ggcagtaatc
    19501 accctatagc catatccacg gacgagctcc tccaagtttt tccccagcag ctcttcctcc
    19561 accaccaaga gcagcacaaa tgacgctttg ccaatcatat aaggctcctt aattcatttt
    19621 aaagtcttct ctgtgccaag gagagagctt ccctacttct tcttcctcgg atcatctcct
    19681 gtttcaaaca tctcaaagag atcataaaag aggcgggtta cagcactgta gtgagtggca
    19741 gagcctgagc tggcataggc cttagtcaac tccatggcct taacaaaact ctcctgactc
    19801 tccgcatcat ctctcttctt aagtgctgcc acgagttttt ctccgacctt ctgctccata
    19861 acgactccca aacctttttg ttttttcagg ccactatttt atgaagagag ttgccagcca
    19921 tcaaagcggg ccgcaatgcc cgagagctct gcctgccgat agagcgcctg aaagaccccc
    19981 tccatcctcg ccagatgttc tgtcgaaatt atccctgccc gcttcagaac aatgatctgc
    20041 cagtcatgcc gggcggcata gcgcccgcac aggaccctac cctcctcgtc ggaggcggca
    20101 aagacaatca tatttaccag accagccttc cacctctgag cctcaaggct ctcagcaccc
    20161 gggcaaacct catactgata ccagatggca gagagattct ctccacaatt ttttcccgcc
    20221 tgcatataac ctccacctct atgataaaat catatcataa gacaagatct ctgttttaca
    20281 taaataaaaa tttagagcgc aggacgcaaa gaggcagcag aaaggggttc cctctccgtg
    20341 aaaaaagaga gggagggggg aaaaagccta gagaagggtc ttggcccgaa caccaataag
    20401 ctctgcggct atactaacgg agatctcctc gggggtctga gcaccgatgg tcagaccgat
    20461 gggagagtgg caacgatcaa tattcgcctg agaaacgcca tcggccaaca gggcgtcgta
    20521 gatggcattt cgtttcttct tactgccaat cataccgata tagcgagcat cggtcttcag
    20581 ggcatctccc agaacagtca gatcatggac atgcccacgg gtaacaatga tgatataggc
    20641 atcttcaggg atggagagat cggtacagca atcctcaaag ctagcgagga cacgcacctc
    20701 atcaacggtg gggaagcgtt ctacattggc aaaatcatct cgatcatcaa ggaccaccgt
    20761 gcgaaagcca agcatggctc ctacccgggc agtaaagagg gagacatgac cggcaccaaa
    20821 gatatagagc ggagccggcg ggataaaggg ttcggcaaag cagagctccg tttcggactt
    20881 actaaaacat ggactctcct tctccatggc ctgtccggcc agggcagagt agtccccaag
    20941 catcacctca tgtcctacgg agcaaagaga atcccccttg gaaaaggtgg tagagagaac
    21001 cgctctctca ccccggcgca gcaggccatc caactcccga taggccaggg cgcagggacc
    21061 ggtggactca atggtctcca ggaggaccga gagattacca ccacagatca tatctgagtt
    21121 agcggccatc tcctggtcca tatcggtaaa ggtaagttct gctcgaccat ccttacaatc
    21181 ctcaagcatt cggcgggcat cacgacaggc gatggcctcc acgataccac cgccgatggt
    21241 accaatggca gtgtgctggg ctcggacaac catcttcgcc cccgaggaac gcggggtaga
    21301 gccggagctc tctaaaacag tggcaagtac acagggttca ccctgctcaa taagttcaca
    21361 cagggaacgg acaaaggcct tcatagatta tctctcctca tctatctgta gacagcgttt
    21421 ggccaaaccg ggaacagccg gcctgccgtc gttttttatc tcaatactta tttgcaagga
    21481 acctaactca atggcccgga aaatagtagg tatctttttc agggcaactc ttatggcaga
    21541 ctcaaggcta ccccctcttc cacaggccag gattcccaag cgaccgggag caagcgatgc
    21601 actaaaatcc gccagaccag caacggagta gagagcctcg ttcaactcat ctattgtcag
    21661 taaaggcgaa gaatcttggg gcaaacgacg aatccaggga tcaaggcggc gactggtact
    21721 gccacagggg caggtgtcag ccagaatacg acccagatct ccgctccgat aacgaatcag
    21781 gggcatgccc catcgctgca gggtggtcag caccaattcg ccaaatttac cgtcgggcaa
    21841 gggctggcct gtctctggat cggtgatctc taaaaatata tcggcctccc gcaggtgcat
    21901 acccgaatgg ggggcacact ggacggcacc gccaagaccg gtttcaatca tgccccagtg
    21961 ccgataggct cggcagcccc agattctctc gatattatgg acaacggcgg tggagggggc
    22021 atcccagcag aggaggaccg aggcaatttg gccatgccca agaccacgcc tggcccactc
    22081 acaggcaagc agattaagat gggcggcagg cccaatgaca caatccgcat ccacctggag
    22141 gaggtggtcg acggctgctg ccacctcatc caccattcca tgggagacga tgtgcacccc
    22201 gcgtcgttca agtccctcaa cgagaagacg acccaccccg cccggacggg ctgtgggcat
    22261 aaggagaaag gcggtctgcc cggccgcaac cagatgagcc atgcccgcat caaagtagtc
    22321 caccgttgcc tgcagatcac tctccgtata gaagatgcgc ttaggggcac cggtggtccc
    22381 ggaactctgc acggtcaccg cccgggcaat ctcatcctga gagacacaga gaaactgctc
    22441 cgggccagcc cgaaggtcat cggccgtaac ccggggtagg gccgagaatg cctgaaggct
    22501 atcaagactt tccagctcaa ggccggcaaa atggcggcga taaaaggggc tcttctcccg
    22561 ggcatgcagg atcgtcttct gcagatattt cagctgccag gcactcatct cctctgccgt
    22621 gggcgcgctg ctctcctccg acatacccat acgcctgagg agaagtcgat caagatggga
    22681 tagggccatt gcattttcct cgatacaggg tctcgccatc cattgaggtc aggttatagg
    22741 cgcaaaaggg aatgaggcga ccgtctggag agaccacatg gatacagcac ccccgcagcc
    22801 tctcaaaatc aagggtccag gcatcctgaa aggccatggc cgaaatggcc aggctatggc
    22861 tggcggcccg actgataaat cttcccaaat catcctctag cgccccggcc atgggtaaac
    22921 tctgcttgac tccggcccac tgccgcttaa caaaggattt agccttatcg gccccctctc
    22981 tggctggcct gggagcacag tcacacttgc ctccggcgga gagctttgtc agcccaccct
    23041 cctcggtgac catatagttg ccattaaagg aacagtgaga gtgttcacag cccggaggtt
    23101 gaaaatccgc agcatgaaca gcaccaccgc tctggacctc aagcaggtcc atcagctccg
    23161 gcagggtgat acgctcttca tccccgggcg cctgcggata tctgccaaaa tagctgaccg
    23221 gctgaaaatg aaccccccgc acatggggag agttctgcac agccagatca aggattgccc
    23281 ccaaattatg atcattcaag cccggcacca ccacgggtac cagaacaata ccaattccgg
    23341 cctgagagag ggcctcaata gctgccctct tttctgccat gaggggacga cctcgcagac
    23401 tgctatagat ggcatcttcg gtgccatcaa actgaagaaa gacggaatca aggcccgcct
    23461 cggccagcct ctgagcataa ccctcttcac gggcaatacg cagaccattg gtattgagct
    23521 gaataaaggg aaagcccctc tttttagcca gggcaatgag ctccgccaga tcatcacgca
    23581 tggtgggctc accaccagag agctgaatat tacaaaagcc cgaagcaagc tccacccgct
    23641 ccagcagttg agaaatttct gcctgactgg gatcgggagc agccttcttg ccagaggagg
    23701 caaaacagac gggacaaccc agatcacagc gccaggtcac ctcaagaaga gcagtgcagg
    23761 tgtgctgacc atgagcggca cagaggccac agtcataggg acagcccctg tccaccgcag
    23821 taaaaggggt cttaggctgg gaaggaatct tggtccggga ccactcctta aaggaagtac
    23881 cggctcgcca aactaccgtt ttaaaagcac catgctcagg acactccttc aacagatagg
    23941 tattgccctc aatagtttca tggtgagcgg ggatagcctt caagcaaacg ggacagacac
    24001 ttctagcgat ggagttcata aaagttcacg cccctctgtc ggatcacagc cattatcaag
    24061 caagatctcc cggacccggc catgggcatc agctaacagg gagccacaga gagaggtatt
    24121 catctgcggc gtactaccat caagaatatc a
//
