LOCUS       NC_015318.1            23955 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_015318.1 Hippea maritima DSM 10411, complete sequence.
ACCESSION   NC_015318
VERSION     NC_015318.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:50:34
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1496453
            Orig. end    :: 1520408
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     cand_cluster    1..23955
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /detection_rules="(Fer4_7 and TPP_enzyme_C and POR and
                     POR_N and PFOR_II and not (EKR or Fer4_16))"
                     /kind="neighbouring"
                     /product="Putrescine2spermidine"
                     /product="porA"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="gutsmash"
     region          1..23955
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="Putrescine2spermidine"
                     /product="porA"
                     /region_number="6"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /rules="(Fer4_7 and TPP_enzyme_C and POR and POR_N and
                     PFOR_II and not (EKR or Fer4_16))"
                     /tool="gutsmash"
     protocluster    1..20861
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[1506453:1507314](-)"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(10001..10861)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..20861
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     CDS             complement(767..2056)
                     /locus_tag="ctg1_1531"
                     /transl_table=11
                     /translation="LEFGLDEIIAVLKPKSISLDRDYTIKGFSIDSRAIKEGEVFVGIK
                     GERFDGTDFAPEAVKKSKTFAIVEKKVDCPHIIVNNALGALKRLATYKLKKSGAISVAI
                     VGSVGKTTTKELVADFLSCRYSVCRSLENENNIIGVCKTLLRVEDEDFCVVEVGINNPG
                     EMEEIAAFFEPDNVLFLNVTSTHIGNFENIDAIFKEKSKIINKSSRLVYNADDEILKEA
                     FEGKENSFGFCFFGDCEFRAENNNNVKVEDITLKKPFGLNPYTVLSGFVAAFVFGGFKD
                     ETCFNDKLKAFKPVGYRMRPEILEDKLFILDCYNANVNSMMHAIDELAKLKGRKLAILG
                     DMLELGSFSERFHRDVGLYLNGKDIDLLAVGGDAFFIFDAFNGKKYYCKTKPEAVELLK
                     DKLTDYDIFLLKASRGMRFEDIFTRLKGSQ"
     protocluster    942..23955
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[1507394:1510408]"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="2"
                     /tool="gutsmash"
     proto_core      10942..13955
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="2"
     cand_cluster    942..23955
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(Fer4_7 and TPP_enzyme_C and POR and
                     POR_N and PFOR_II and not (EKR or Fer4_16))"
                     /kind="single"
                     /product="porA"
                     /protoclusters="2"
                     /tool="gutsmash"
     CDS             complement(2041..3420)
                     /locus_tag="ctg1_1532"
                     /transl_table=11
                     /translation="MECLKRIEEFRPVDMVYDSREVSEGFVFFAIKGTKVDANRFVPNI
                     LAKFKRVLVVSENGFDDERCIKVDDVRKCMGLAADHFFNHPSKKLKVVGITGTNGKTTT
                     TYLLRSIFDNSEIIGTTGWTLKDERFKLNNTTPESLDLHRILNRMAMANSEYCFTEVSS
                     HALSFNRIEGVDFALKVFTNISQDHLDFYDNLENYAKTKLSFFERLKPKVVNADDSYGR
                     MLIDAATISYGFSDFAFIKPIVYEYSLDGIKAKLNVARRTISITSPLIGDYNLYNIMAA
                     LGVALFFGVDFARIEEGIAKSKGAPGRLEFFQKDGAYAVVDYAHTDDAMRNVLEALNKI
                     KKGRIITVFGAGGDRDRTKRPKMGSIAESLSDVVVVTSDNPRSEEPLAIIDDILEGISD
                     RDRVIVEPDRFEAIKKALGMAEKGDLVTILGKGHEDYQILKDKTIHFDDREVVRRLWNL
                     D"
     CDS             complement(3553..5247)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 382.1; E-value:
                     8.9e-117)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1533"
                     /sec_met_domain="AMP-binding (E-value: 2.5e-115, bitscore:
                     382.1, seeds: 145, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding_C (E-value: 4.7e-21, bitscore:
                     72.3, seeds: 272, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSYAFEGSTTKFIAKTIGDMLDENAEKYANNDCIVSLHQNIRMT
                     YKEFKQEVDRLAKGLLALGIKKGDKVAIWSTNNVEWVLTQFATAKIGAVLVTINPAYRT
                     NELEYALKQSEVNTLILIESFKTSDYIHMFYEVAPFARGAIPGQIHSNKLPHLRNVVCI
                     SDTKHTGMFKWKDVLSMASRVDDSELRDRQKSLDFDDAINIQYTSGTTGFPKAATLSHF
                     NIINNGFFVGQAMKFTDKDRLCVPVPFYHCFGMVMSNLTCTTHGATIVLPSEYFNAEAT
                     LEAVEKEKCTALHGVPTMFIAELEHPRFKEFDLTSLRTGIMAGSPCPVEVMKRVNKEMH
                     MEQVEIAYGQTEASPVITQTLADDTLEHRTETVGRPLPYIEVKIVNPETGEILPVGEQG
                     ELCARGYNVMKYYYNNPQATKEAIDEDGWLHTGDLATMDEDGYFKITGRIKDMIIRGGQ
                     NIYPREIEEFLYTHPKVADVQVIGVPDKKYGEEVCAWVRLKEGETATEEEIKEYCQGKI
                     AHYKIPRYIKFTDSFPMTVTGKIRKVEMREISIKELGLEEVAKIKTA"
     CDS             complement(5257..6933)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 284.2; E-value:
                     4.8e-87)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1534"
                     /sec_met_domain="AMP-binding (E-value: 1.3e-85, bitscore:
                     284.2, seeds: 145, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding_C (E-value: 1.1e-24, bitscore:
                     84.0, seeds: 272, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHNMLNYEEEVKNFKIDVPEYYNFAFDVVDKWAEDRTKLALVWA
                     DTPGKNIKKYSFWDISVMSNKFANVLLKLGIKKGDNVFVMVPRIVEWYAVMLGLNKVGA
                     VALPAPNILMPEDIRYRIRKGDVKMAIASASNASKVEAACNNGDCPTLDVKMIIDGDLE
                     GWLSFENQMDMASDKLSRDDVEPTKSTDPLLIYFTSGTTKYPKMVMHDQAYALAHIVTA
                     KYWHDLKPTDLHWTISDTGWGKAVWGKLYGQWQIGSAVFMHNAGSHFDAKITLKLLTTQ
                     GITSFCAPPTVYRMLIQEDLSQYDFSSLRHCTSAGEPINPEVIKAWKNATGTLIYDGYG
                     QTETVLIVANYPCMPIKYGSMGKPVPGYDVRIVDDDGNDMPVGEPGHIAVKIKPNHPIG
                     VAKEYYKDEAATAEAFRDDFYYTGDRAYMDADGYFWFYGRADDVIKSSGYRIGPFEVES
                     ALQEHPAVAESAVVGSPDPIRGTIVKAFIILAKGYEPSDELIKDIQDFVKNKTAPYKYP
                     REIEFVKELPKTISGKIKRAVLRRMEIEKKLGKKGTNGSFV"
     CDS             complement(7055..8410)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1535"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.4e-27, bitscore:
                     92.7, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGNPDKKFSNFFNGVKPSGLRLAQTVFEKRAQKELKEGKRPIEA
                     VNVAIGSVSLKTHPKLLERFLNPTNEELINGIWRYGETPGTQKANEVFIKIIRAFLPDG
                     VNPKLYSIIQDGGSGAMRTAILGLCGDAGKDDRPLLVMNPTYTNYKAVADELGRRIVAV
                     ERALDRSGNFNHVAVEKIEEAVKKYKPGALLIIPYDNPSGQLMRQKTINEYVRICLEND
                     MFIISDEAYRGLYYTDDEPPSVWRVTNKDVPGVEEAGIRISIESLSKTFNSCGLRMGAL
                     VTDNEAFRDRASAANTTYLCPSIIDQHIVEGLYDESYEDIRGWVASLRDYYKDLLEHMY
                     DEFKKRMPKAIVSKPEASIYMVLDLREMVDDSFEAEDFVMYCAREGEVEIDGKRYTLLV
                     SPMWGFYNVIEGRNPGHTQVRIACVEPEDKMRIVPELFSRLFEEYLSKRDKR"
     CDS             8720..9952
                     /locus_tag="ctg1_1536"
                     /transl_table=11
                     /translation="MKKRLISLVAAAALVGGIATVSAPVSAQAGTVAVKGDTQVQMYGF
                     IRYIAGWTNKMETNTSEFLNMPYKDYSGQDDPSSNDTKFMSSTYQTRLGLNFKNEDANL
                     TGKIEAHFYDGSFGIRKAYIQHNFDNFYLRIGRDYGLELDGGSFSTAFEAPVGMNGASR
                     NPQIKAGTSFDLGGAKLDAGLALEDVSYTNVSGVNNASISRKVMPGVAAKLALSFETGF
                     GAPARIYAYGMITPLKIKYLDTTGKYTEKSKTPVIFGTGLKLPVSMVTLNVNYVYGKGA
                     TKFAGLNEDTNNNIITPYSYYYDGSSLNTNRFDAFNIEAKIKPMPCVAVAGGYDYAKFK
                     HSYGLTTAGNKDQKPYVSTYFANVAIQTTKYTQLTLEWRHVEDKYFQTDTNGDDVKVKG
                     NQYFMRYTYSF"
     CDS             complement(10001..10861)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1537"
                     /sec_met_domain="Spermine_synth (E-value: 7.8e-54,
                     bitscore: 178.6, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 7.6e-16,
                     bitscore: 54.5, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAYFPEFWFTEKYTGTCGFTFKIKRVLSTEQSPLQRLDILETYDF
                     GRVMLLDGLVMFTERDEFVYHEMIAHLPLFAASDPKDVLIIGGGDGGTAREVSKHIYLN
                     SITNVEIDEVVVKNSKKYTPFVGCGFDNEKVNLIIGDGIEFVKDKKGLYNVVIIDSTDP
                     FGPAEGLFNSEFYGNVRDALRDGGIVVAQAENTYYDKRWMMRSVNNMKKAFGKNNVAIY
                     QAAIPTYPSGTWVFAIGWKSGEHPRDRFDEERFNKLNLKLKYYNPEIHKAAFALPSYVE
                     EILKG"
     CDS             complement(10942..11514)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1538"
                     /sec_met_domain="POR (E-value: 3.6e-33, bitscore: 111.8,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAFHYELRFGGVGGQGSLTAGTILAHAAVFRTKYYATQVPTYTSQ
                     VRGGAAKADIIISDEPITFPESTNVDFFLSTHQKAYDAYKGDLKEDAYVLVDSGLVVVP
                     DDDAKKYKVYEYPLVRTAKYEIGNVVTMNILAVGICLGLTEVLPIDAVRDTVKEEVPPA
                     FIDMNMKAFDMGLEVGRKFKAEGPTKK"
     CDS             complement(11530..12477)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1539"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.4e-35, bitscore:
                     117.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVDYTKYLRMEKMPLYWCPGCGDGIVLKCYLEAIDELGWKKDDC
                     AMVSGIGCAARVTGYVDFHTLHTIHGRAIAVASGIKMSHPDKHVFVFGGDGDLVHIGGN
                     HLVHACRRNIDITVVLINNWIYGMTGGQHSCTTPPGAKASTAPRGTFEPTIDVCKMAIG
                     AGAGYVARGFAGDPTRLTKLIKEGLAYKGFSLIEVFSPCPINFGRRNKLGDPAKLMDYM
                     KGFLVSSAKAKKMSEEELKGKFVMGVLHKDESKPELTESYKALVEKAQASDEYWAKYVK
                     GSVTDADKYKITREELKGLYPYDVETPLKEWKKL"
     CDS             complement(12477..13673)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1540"
                     /sec_met_domain="PFOR_II (E-value: 3.1e-23, bitscore: 78.8,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 3.7e-63, bitscore: 210.1,
                     seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRIGFMDANAAIAEAAVVAGLGFYAGYPITPSSEVPERLSKIMP
                     ERGVPFMMMEDEIASINACVGAAASGVKAMTCTSGPGLSLKQEAFGMACMFEVPLVVVD
                     VMRGGPSTGLPTRPSQGDIMQARWGTHGDHPVIAIAPANAQEAVFETIRAFNLAEKFRQ
                     PVYILTDGSLSHLHTKVYIPDPEEVEIVDRQAPDVEPDEYYPYDYNYEIPPLAPWWTKD
                     GKSYRYHMSSLIHDKTGFPTVVPKYVQWLLNRMHSKITNHLDEILKYEYYKMDDAETCI
                     IAFGSTAEAARVAIDEARKEGIKVGMFRPLTVWPSPEQQIKDIAGKVKNIIVPEMNLGQ
                     YILEVQRIVGDAANVYGISQATGTLIRPSQILEKIKNPEKKVEIVMTDEEIRRFGGGE"
     CDS             complement(13683..13955)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1541"
                     /sec_met_domain="Fer4_7 (E-value: 4.2e-10, bitscore: 36.8,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 3.3e-06, bitscore: 23.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 1.9e-06, bitscore: 24.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.4e-05, bitscore: 22.1,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEKRMPVEINEKLCKGCGLCVNVCPKNVLEMVEDLHVWMGTIAK
                     VARPEDCIRCKMCENICPDFAITVADIGVELEFADSKGNTVTKSK"
     CDS             complement(14012..16249)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IDH"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1542"
                     /sec_met_domain="IDH (E-value: 0.0, bitscore: 1272.6,
                     seeds: 182, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATGKPTIVWTKTDEAPYLASFSLLPIVKGFVKHADVDVEVRDIS
                     LAGRILATFPEYLKEDQRINDDLAYLGELVNKPEANIIKLPNISASVVQLKEAIKELQE
                     KGYNVPDYPEEPKDEKEKEIKERYAKVLGSAVNPVLRQGNSDRRLPTSVKEFAKKYPDS
                     MGLPLKPWPEDSKTHVAHMDGGDFYEHEKSFTTDREMDIEIQFVDENGNAQTMKKLHLL
                     KGEVFDGTFMSVKKLREFFDQQIKDAKEKGVLLSLHLKATMMKVSDPPIFGHMVEIYFK
                     DVFEKYKELFKELGVNPNNGLRDLYARIQKLPEDQRKQIEADIEKVYEKNPELAMVDSR
                     KGITNLHAPNLIIIDASMPPMIRDGGKMWNKNDELQDTKAVIPDRCYATMYKEVVEDCK
                     KNGQFDRTTMGDVSNVGLMAMKAEEYGSHDKTFLAPSNGTVRVVDENGNVLIEHNVEKG
                     DIWRGCQAKDEAIRDWVGLAVRRARATGYPAVFWLDENRAHDAELIKKVKEYLKDYDTE
                     GLDIRIMRPVDAMRFSLERIRKGLNTISVTGNALRDYLTDLFPILEVGTSAKMLSIVPL
                     LAGGGLFETGAGGSAPKHAQQLIEEGHLRWDSLGEFGAIFASLEHIAERYGNKKAKVMS
                     DAADKAMTKVLENQKWPGRKVHQLDTRGNHFYFAMYWAEALAEQSEDEELKKIFEPIAK
                     EMKENEEKIINDFDVVQGKPSEIDGYYWPDEEKVEKIMRCSETLNSIVSKL"
     CDS             16441..17067
                     /locus_tag="ctg1_1543"
                     /transl_table=11
                     /translation="LINPNIFLMVIPFLVAVVFHEVSHGYVAYKLGDNTAKFAGRLTLN
                     PVAHIDIFGTIVLPAILIIAHSPILFGWAKPVPVNFFNLKKPKRDSAIVAAAGPTTNIL
                     LAVLFAIIYRISLFLPASFIQQPLMITCLYGVQLNLIFAFFNLIPILPLDGGRILAAFL
                     PPKWAYNFSKLEPYGIYIVIALLFLGIFDFIFTFFVLPLSSILLS"
     CDS             17077..18093
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1544"
                     /sec_met_domain="Radical_SAM (E-value: 3.3e-21, bitscore:
                     73.1, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEAYLYSRLEDNKVQCNLCSFRCKLADGKTGICGVRKNEGGTLY
                     STVYARAVAKAIDPIEKKPLFHFLPSTKSFSIATVGCNFNCLNCQNADISQYPKENAGA
                     VVGDVYPPEKVVEDAISAGCKSIAYTYTEPTIFFEYAIDTAKLAKEKGLKNIFITNGYM
                     TKETIDMMDGLIDAANVDLKAFNDAFYMQICGGARLKPVLESIEYMKSKGIWVEVTTLV
                     IPTANDDPAEAMQIAEHIYNIDPSIPWHISRFYPAYKFSDVMPTPPEVIKNFRQIGLSI
                     GLKYVYTGNMLGDEGEHTYCPNCGELLIARYGYEILSYAIKDGKCPKCGTKIDVVES"
     CDS             18095..18610
                     /locus_tag="ctg1_1545"
                     /transl_table=11
                     /translation="VRLLFAEEEIEKRIEKLAKLLDEKLRSKQEKTVMLYIEKGGKPFF
                     EKLTQKMKTNPIKDSIRVKSYAGDRSTGKIEWIKKPSVDLKGKHCIIVDDILDTGKTIK
                     EVKNYMLSQGATGCEICVAVNKHERREEDIEPDYYLFDLDKGFIIGFGMDYNEKYRELP
                     AIYLMGES"
     CDS             18631..19623
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiI"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1546"
                     /sec_met_domain="ThiI (E-value: 3.3e-09, bitscore: 33.3,
                     seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNLNKKCVALYSGGLDSLLAILIVKSLGVEVYPLFVQTPFYNKE
                     IDKLKEQLNKSGLALETARDDKAYIEMLLNPRFGYGKNLNPCIDCKAFFYKKAKEYADK
                     IGASFIITGEVLGQRPMSQRSYTVLRTIEKHAGLIDLVLRPLSAKCLKETIMEKEGIVD
                     RDKLYCIQGRTRKAQFELAKTFGIEEFESPAGGCLLTDTQFSARLKEMLDKKDELNSPV
                     AIELLKIGRHFRVDGFKFIVSRNAEETKFLTDNFSDLPQIRCLNSPGGVGVFLKEPHIE
                     TIITAAAILKRYSKKAQNLIFKGSREFIIDVKPMSDERLNSYRVGGDNA"
     CDS             19616..20680
                     /locus_tag="ctg1_1547"
                     /transl_table=11
                     /translation="MLKEKLEELEEKYKYIETQLSDPNVVGDLDRYKSLSSEIKKLTPI
                     VEKAKEYRNILRQIEENEELLEDEELKELAKEELKHLKERLPELEQEIKLLLLPKDEAD
                     DRDVILEIRAGTGGEEAALFAADLFRMYSRYAENKGFKVEVLSKSLSDTGGIKEIIAEI
                     KGKGAYHLFKHESGTHRVQRIPITESQGRIHTSAATVAVLPEAENVDVEIKPEDLRIDV
                     FRASGHGGQHVNTTDSAVRITHLPTGMVVSCQDEKSQLKNKEKALKILKSRLYDFYRRK
                     KDEERAKERKSQIGSGDRSERIRTYNFPQGRVTDHRINLTLYKLDSIMEGDLDELIEAL
                     IVDEQARKLKESGM"
     CDS             20688..21779
                     /locus_tag="ctg1_1548"
                     /transl_table=11
                     /translation="MGFKCGIVGLPNVGKSTTFNALSRGNAESSNFPFCTIEPNVGIAE
                     VKDERLYKLAELVNPKKITPAVVEFVDIAGLVKGASEGAGLGNRFLSHIRDVQVIVHVV
                     RCFEDEDIVHSVGEVDPKRDIEIIDTELMLADLQTIENRENKTLKIAKSGDKKAKAELE
                     ILERFKNLLESGKPIRSESLKAEEVDLVNELRLLSAKPVIYVANVSEDSLDGNEYSETV
                     KQIANKENAPVIVLSSKVEEELSRLSEQERKEFMEMLGLKESGLDRLAKVGYQMLGLIT
                     FFTAGPKEVRGWTIKKGTTAKEAAGVIHSDIERGFIRAEIIKYEDYIAAGGEKQAKEKG
                     LMHLEGKDYIMEDGDVVYFRFNV"
     CDS             21776..22690
                     /locus_tag="ctg1_1549"
                     /transl_table=11
                     /translation="MRVIRDIYAECDIEATAIALGNFDGIHRGHQALINETVKLSKKLN
                     LTPAVFTFHPHPKKVIEHIDEPFLIQRFKEKTKIIESFGIDIVVCAHFTQAFAEMEPYN
                     FVKDILIDRMHARAICVGHDYTFGKKALGTTKTLRELSNSLGFELIVIPPFKINGTIVS
                     STRIREFLRTGQIGLANEFLGRNYTISGIVKEGEGRGSSLGFPTANIYPTNEILLTNGV
                     YAAYVYIDSKKYAAAVNVGVNPTFKGTQKHIEAFIFDFNGDLYRKRITIEFIDFIRPER
                     KFKRIDDLISQIKQDIKQIKTIL"
ORIGIN
        1 agccaagcaa agaaccggct aaagcggcaa gtaatacact tatttcacct gaaccaacaa
       61 catgcggtag gtgaagatag taagcaaaaa tagcattacc cgttgcatag gcaaaaacag
      121 tcaaagaaaa tatggttgtt aaggatggtc ccgtggccaa cccgtcaagg ccatcggtta
      181 aattaacggc gtttgagctg cctactatca caaaaacagc cacagccaga taaaaataac
      241 ctaaatcaaa gactccgtgt tttataaaag gtaagtaaaa acaacctgca caccccgtta
      301 atatctgctc aaccctgaat atcatgaacg ccacaacaag cgctacaatc gtttgcaaaa
      361 aaaacttggt tttggccttt agaccattgt ttttccctct ttttatcttc agaaaatcat
      421 ccaaaaagcc tataagcata aacaaaaaac tacccaaaag aacaatccaa gcaagcggtg
      481 aatcaaatcg tatccacatc aaagctgaaa caaaaaagcc gctccaaata ataagccctc
      541 ccacagtggg agtaccgctt ttctgtttgt gtgtttgtgg ctcatagccc ttaaaactat
      601 cctcaaactg catgctttta agtttaggta taaggatttt gccaaaccat aaagataaac
      661 caagcgctgt aagtgatgcc ataatcatcc taaaggttat gtagtgaaaa acattgaatg
      721 gtgaaaaaat atgagttagt ttttgataaa atatataata gaacatctac tggcttcctt
      781 ttaatcttgt gaatatatcc tcaaatctca tgccccttga tgccttaagt agaaatatat
      841 cataatcagt aagtttatcc tttaaaagct caacagcctc tggtttagtt ttgcagtaat
      901 acttcttgcc attaaaagca tcaaagataa aaaatgcatc ccctccaacg gccaacaggt
      961 ctatatcctt tccatttaaa tacaaaccaa catccctgtg aaatctttct gaaaaactac
     1021 caagctcaag catgtctcct aatatagcca acttccttcc ttttagttta gcaagctcat
     1081 ctatagcatg catcatggag ttaacattgg cattatagca atccagaata aacagcttgt
     1141 cttcaagtat ctcgggcctc attctatatc caacaggctt aaacgccttt agcttatcat
     1201 taaagcaagt ctcatcctta aaaccaccga aaacaaaagc ggcaacaaaa ccggacaaaa
     1261 ccgtataagg atttaaacca aagggctttt ttagtgttat atcttcaact tttacattat
     1321 tgttgttttc tgccctaaat tcacagtctc caaaaaagca aaaaccaaat gaattttctt
     1381 taccctcgaa ggcttctttt aatatttcat cgtctgcatt atacacaagc cttgagcttt
     1441 tatttatgat tttggatttc tccttaaaaa tagcatcaat attttcgaag ttccctatat
     1501 gcgtcgaggt tacatttaaa aacaagacgt tgtccggctc aaagaaagcc gctatctctt
     1561 ccatttctcc tggattgttt atacccactt caacaacaca gaaatcctca tcctcaaccc
     1621 ttaaaagggt tttacataca cctattatgt tgttttcatt ctctaaactt ctacatacgc
     1681 tatatctgca agacagaaag tccgctacaa gttctttggt tgtcgtctta cctacagaac
     1741 caacaatcgc aacagaaata gctccggatt tttttagctt atacgttgcg agtctcttta
     1801 aggcacctaa agcattatta acaattatgt gcggacaatc cactttcttt tccactatgg
     1861 caaatgtttt actcttcttt acagcctcag gcgcaaaatc tgtaccatca aacctctcgc
     1921 cctttatacc aacaaaaacc tctccctctt ttatggcgcg cgaatctatg gaaaaacctt
     1981 ttattgtgta atctctatcc aaagagatgc tttttggctt taaaacagct attatctcat
     2041 ctaatccaaa ttccaaagcc ttctcaccac ttccctgtcg tcaaaatgaa tcgttttatc
     2101 ctttaaaatc tgataatcct catggccctt acccaaaatc gtaaccagat cgcctttttc
     2161 agccataccc aaagccttct ttatagcctc aaacctatca ggctcaacaa taaccctgtc
     2221 cctatcgcta attccctcca aaatatcatc aattatagct aaaggctcct cacttcttgg
     2281 attatcgctt gtaacaacaa caacatcact taaactttct gctatagaac ccatctttgg
     2341 cctttttgtt ctatccctat caccgcccgc accaaagact gttataatcc tgcccttctt
     2401 tattttattc aaagcctcta aaacattcct catagcatcg tctgtatgtg cataatcaac
     2461 aacagcataa gcaccgtctt tttggaaaaa ctcaagccta ccaggcgcac ctttgctttt
     2521 tgctatcccc tcctcaatcc ttgcaaaatc cacaccaaag aataatgcaa cgcctaaagc
     2581 agccattatg ttatacagat tgtaatcacc tataagtggt gaggttatgc taatagtccg
     2641 tcttgccaca ttgagctttg cctttatgcc atcaagcgaa tactcataaa caataggctt
     2701 tataaaagca aaatcggaaa aaccataact aattgttgca gcatcgataa gcatcctgcc
     2761 ataactatca tcggcgttta caaccttagg ctttagcctc tcgaagaagg aaagcttcgt
     2821 ttttgcatag ttttcaagat tatcgtaaaa gtccagatgg tcttgagata tattggtaaa
     2881 tacctttaat gcaaaatcaa caccctcaat tctattaaag cttaaggcat gagaagaaac
     2941 ctcagtaaag caatactcgc tattagccat agccatcctg ttgagtattc tgtgcaaatc
     3001 caacgattca ggcgttgtgt tgtttagctt aaacctctca tcctttaaag tccagccggt
     3061 tgtgccaata atctcgctgt tatcaaatat gcttctaagc aggtatgtcg tggtggtttt
     3121 accgtttgtc cctgttatac ccacaacctt aagttttttt gaagggtggt tgaaaaagtg
     3181 atcagcagca agccccatgc actttctaac atcatcaacc tttatacatc tctcatcatc
     3241 aaacccattc tcacttacaa ccaaaaccct cttaaattta gccaaaatat tcggtacaaa
     3301 cctatttgca tcaacctttg taccctttat cgcaaaaaat acaaaaccct cactgacctc
     3361 gcgggagtca tagaccatat caactggcct aaactcttct attcttttca agcactccat
     3421 agctaaaaac cctaaaatct tattgaccac aaaggtcgct tttaaaatcc tacattttta
     3481 atcttttgtc aagacaataa aaaaagccgg cctaaagccg gctaaaaagt atttacttaa
     3541 tctctgttca atctaagctg tctttatctt tgctacttcc tcaagtccaa gctctttgat
     3601 agaaatttct ctcatctcaa cttttctaat cttgcctgta acggtcatcg ggaatgaatc
     3661 ggtaaatttg atataccttg gaatcttgta atgagctatc ttaccctggc agtactcttt
     3721 aatttcctct tcagttgcag tctcaccctc tttgagtcta acccaggcac agacctcctc
     3781 gccatatttc ttatctggca ctccaataac ctgaacatca gcaacctttg gatgggtata
     3841 gagaaactcc tcaatctcgc gtggatagat attctgcccg cccctgatta tcatatcttt
     3901 aattctacct gtaatcttaa aatagccatc ctcatccatg gttgctaaat caccggtgtg
     3961 caaccatcca tcctcatcaa tagcctcttt ggttgcctga gggttattat agtaatactt
     4021 cataacatta tacccccttg cacacagctc tccctgttca cctaccggca aaatttcacc
     4081 cgtttctgga tttactattt taacctcaat atacggtaga ggtcttccta cggtttccgt
     4141 tctatgctca agcgtatcat cggccaatgt ttgggttata acagggcttg cctctgtctg
     4201 gccgtatgct atctcaacct gttccatatg catctctttg tttaccctct tcataacctc
     4261 aacagggcag ggagatccgg ccattatacc ggttcttaga cttgtcaggt caaactcttt
     4321 gaagcgcgga tgctcaagct cagctataaa cattgtagga actccatgta gtgctgtgca
     4381 tttttccttt tcaacagcct caagcgtggc ctcagcattg aagtattcac ttggcaaaac
     4441 tatcgtagca ccgtgagtag tgcaggttag attactcata accataccaa aacagtgata
     4501 aaatggcaca ggcacacaca atctatcctt gtcggtaaac ttcatagctt ggccaacaaa
     4561 aaagccattg tttataatat taaaatggct caatgttgca gcctttggaa aaccggtagt
     4621 acctgatgta tattgaatat ttatagcatc gtcaaaatca aggctcttct gcctatctct
     4681 aagctcacta tcatcaaccc ttgatgccat agataaaacg tctttccatt taaacatgcc
     4741 ggtatgttta gtatcgctta tgcatacaac atttcttaga tgtggcagtt tatttgagtg
     4801 aatctgaccc ggtattgcac cccttgcaaa cggggcaacc tcataaaaca tatggatata
     4861 atcagatgtt ttaaagctct ctatcaaaat taacgtattg acctctgact gttttaaggc
     4921 atactcaagc tcgtttgttc tgtatgctgg gtttatcgta accaaaactg cccctatctt
     4981 tgctgtggca aattgcgtta aaacccactc cacgttattt gttgaccaga tagccacctt
     5041 atcgcctttt tttataccca aagccagaag gccctttgca agcctatcaa cctcttgttt
     5101 aaactcctta taagtcattc taatattttg atgtaaacta acaatacagt cattgtttgc
     5161 atatttttcg gcattctcat ccaacatatc gcctatcgtt ttggcgataa atttggttgt
     5221 tgagccttca aatgcataac ttaacatggc accctcctaa acaaacgagc cgtttgtgcc
     5281 ttttttacct aatttcttct caatctccat ccttcttaaa accgcccttt taatcttgcc
     5341 gcttatggtt ttgggtagtt ctttgacaaa ctctatctct ctcggatact tataaggtgc
     5401 agttttattc ttaacaaaat cctgaatatc cttaatcagc tcatctgagg gttcataacc
     5461 cttagcaagt atgataaacg ccttcacaat tgttcccctg atagggtctg ggctcccaac
     5521 aacagcactt tctgccacag ccggatgctc ctgaagcgca ctttcaacct caaacgggcc
     5581 aatcctgtat cccgatgatt tgattacatc atcggctcta ccataaaacc agaaataacc
     5641 atctgcatcc atgtaagccc tatcgccggt gtagtaaaaa tcgtccctaa aagcttcagc
     5701 cgtagcagct tcatctttgt aatactcctt tgcaacacct attggatgat tgggctttat
     5761 cttaacagct atatgaccgg gctcacccac cggcatatca ttaccgtcat catcaacaat
     5821 ccttacatcg taacccggaa caggcttgcc catagagcca tactttatcg gcatacaagg
     5881 ataatttgca acaattaaaa cagtctcagt ctggccgtag ccgtcataaa tcaacgtgcc
     5941 cgttgcgttt ttccatgcct ttataacctc agggtttata ggctcacctg ccgaggtgca
     6001 atgcctcaga gatgaaaagt catattgact caaatcctcc tgaatcaaca tcctataaac
     6061 cgtgggcggt gcgcagaatg aggttatacc ttgggtagtt aaaagcttaa gtgtaatctt
     6121 ggcatcaaaa tgtgagccgg cattatgcat aaacacggca gagcctatct gccattgacc
     6181 gtaaagttta ccccaaactg ccttacccca acctgtatca gaaatcgtcc aatgcaaatc
     6241 tgtaggtttc aaatcgtgcc aatatttggc agtaacgata tgagccaaag catatgcctg
     6301 atcatgcatt accatctttg ggtatttcgt tgtgccgctt gtgaagtata ttagaagtgg
     6361 gtctgtagac tttgtaggct caacatcatc ccttgatagt ttatcagagg ccatatccat
     6421 ctgattctca aaagacaacc acccctcaag gtcgccgtct ataatcattt tgacatcaag
     6481 cgtagggcaa tctccattgt tacaggcagc ctcaaccttt gatgcattgg atgcgctggc
     6541 tattgccatc ttaacatcac ctttccttat cctgtagcgt atatcttcag gcatcaggat
     6601 attgggggca ggtagtgcaa cagcacccac cttattcaaa ccaagcatca ccgcatacca
     6661 ctcaacaata cggggaacca taacaaatac attatcgccc tttttgatgc ccagcttaag
     6721 caaaacattg gcaaatttat ttgacataac agatatatcc caaaaggaat atttctttat
     6781 atttttaccc ggcgtatctg cccaaaccaa tgcaagtttt gttctatctt cagcccactt
     6841 gtcaacaaca tcaaaagcaa aattataata ctccggcaca tcaattttaa aattcttaac
     6901 ctcttcctca taatttaaca tgttatgctt catcttaaaa aacccccctc tcctctttta
     6961 aagccattta ttaccaaaaa catatcaaaa agtcaatatg atttacaaac taatttatct
     7021 gtctttttta atttttaagg tatatattac aaaattatct tttgtctctc ttggataaat
     7081 actcctcaaa caacctcgag aaaagctcag gcacgattct cattttatcc tcaggctcaa
     7141 cacatgctat tctaacctgc gtatggcccg gattcctacc ctctataaca ttgtaaaagc
     7201 cccacatcgg gctaacaagc aaggtgtatc gcttaccatc tatctcaacc tcaccctccc
     7261 ttgcacaata cataacaaaa tcctctgcct caaaactatc atccaccatc tctctcaagt
     7321 ctaaaaccat ataaatagaa gcctcaggtt ttgagacaat ggctttgggc attctctttt
     7381 taaactcatc atacatatgc tcaagcaaat ctttataata atccctcagg gaagccaccc
     7441 agccccttat atcctcataa ctttcatcat aaagaccttc aactatgtgt tggtcgatta
     7501 ttgaaggaca aagataggtt gtgttagccg cagaagccct atccctaaag gcttcattat
     7561 ccgtcaccaa agcacccatc ctcaaaccgc atgagttaaa tgtcttggat aagctctcta
     7621 tgcttatcct tatgcccgcc tcttcaaccc caggcacatc cttatttgtc actctccaca
     7681 cactcggagg ctcatcatct gtgtagtaaa gccccctata ggcctcatcg cttatgataa
     7741 acatatcatt ttcaagacag atcctgacat attcgtttat cgtcttctgc ctcatcaatt
     7801 ggcccgatgg gttgtcatac ggtataatca acaaagcacc tggtttatac tttttaacag
     7861 cttcttctat cttctcaaca gccacatggt taaagtttcc gctcctatct aaagccctct
     7921 caaccgctac aatcctcctg ccaagctcat cggcaacggc cttgtaattg gtgtatgtag
     7981 ggttcataac aagcagcggc ctatcgtctt tgcctgcatc gccgcataaa cccaaaatgg
     8041 ctgtcctcat ggcccctgag ccaccatcct ggataattga gtataatttt ggatttacac
     8101 catcaggcaa aaatgccctt attattttga taaacacctc attggctttt tgagttccag
     8161 gtgtttcacc gtatctccat atgccgttaa ttaactcttc attagttgga tttaaaaatc
     8221 tttcaagcag cttggggtgg gtttttaaag aaacactgcc tatggcaaca ttaacggcct
     8281 ctataggcct tttaccttcc ttcaactcct tttgtgccct cttttcaaac acagtttggg
     8341 caagccttaa cccggatggt tttacaccgt taaaaaaatt tgaaaacttt ttatcagggt
     8401 ttcctaacat tatatattac ctccccctct ttgtataagt ggatgaattt tatacataac
     8461 aaaaaagctg tcaagagtaa attcttctta actcagaaac caattttaaa gaatttttta
     8521 gggttaaaaa attaaataat gttaaaattt attgttgact taccgaaaaa aatatataga
     8581 atgtgaattg tgaatttctt tttaaggggg tgggagctaa agaaaaagtc ggaaaaagac
     8641 ttgacaaacc agtaggttgg gcttattatg tgaaagtgat gcagaaaaat tttaaaaact
     8701 ttgttaggag gttttaaaca tgaagaaaag gttgatttca ttggtagcag cagcggcatt
     8761 ggtaggtggt atagctactg tttctgctcc tgtatccgca caggctggca cagttgctgt
     8821 aaagggtgat actcaggttc agatgtatgg attcatcagg tatatagctg gttggacaaa
     8881 caagatggaa acaaacacga gtgagttctt gaatatgccc tacaaggatt acagcggtca
     8941 agatgatcca tccagtaatg atacaaaatt tatgtccagc acataccaaa caagattagg
     9001 gttaaatttc aaaaatgaag atgcaaattt aacaggtaaa attgaagctc atttctacga
     9061 tggttctttt ggtataagga aagcttatat tcagcataat tttgataact tctatctacg
     9121 tattggaagg gattatggtc ttgagctaga cggaggatct ttttcaactg ctttcgaggc
     9181 tcctgtagga atgaacggag cttcaaggaa tccacagata aaggctggaa caagttttga
     9241 cctaggtgga gctaaacttg atgcaggttt agcccttgaa gatgtttctt acacaaatgt
     9301 aagtggtgta aataatgcta gcatcagtag aaaagtaatg cctggtgtag ctgcaaaact
     9361 agctttatct ttcgaaaccg gttttggtgc cccagcaagg atttatgctt acggtatgat
     9421 aactcctctt aagataaaat atcttgatac caccggtaaa tatacagaaa aaagtaaaac
     9481 acctgttatt tttggaacag gtttaaaact tcctgtatcc atggtcacac ttaatgttaa
     9541 ttatgtttat ggaaaaggtg ctacaaaatt tgctggctta aatgaagata caaacaataa
     9601 tataataaca ccttattctt attactatga tggtagcagc ttgaatacta acagatttga
     9661 tgcttttaat attgaagcta aaataaagcc tatgccttgt gtagccgttg caggtggtta
     9721 cgattatgca aaatttaaac attcttatgg gttaactaca gcaggcaata aagatcaaaa
     9781 accttatgta tctacatact ttgccaatgt tgccatacaa acaacaaaat acacacaatt
     9841 aactcttgag tggagacacg tagaagacaa atatttccag actgacacaa atggagatga
     9901 tgtaaaagtt aagggaaacc aatatttcat gcgctatacg tacagcttct aatcaaagca
     9961 aaaacaaatc ctaagcgggg ctaaagcccc gcctttttta ttaccctttt aaaatctcct
    10021 caacataact cggcaaagcg aatgctgctt tgtgaatttc agggttgtaa tactttagct
    10081 ttagattgag tttgttaaac ctctcctcat caaacctatc ccttggatgc tcacccgatt
    10141 tccaaccgat agcaaagacc catgtgcctg atggatatgt gggtatggct gcctgatata
    10201 tagccacatt attcttgcca aacgcttttt tcatattatt gactgacctc atcatccatc
    10261 gtttatcgta gtaggtattc tcagcctgag caacaactat accaccatcc ctcaaagcat
    10321 ccctgacatt gccatagaac tcagaattaa acaacccctc ggctggacca aacgggtcgg
    10381 ttgaatctat tatgacaaca ttgtaaagcc cctttttatc cttgacaaac tcaataccat
    10441 cgccaattat tagattaacc ttttcattat caaaaccaca cccaacaaac ggtgtgtatt
    10501 tcttgctatt tttaaccaca acctcatcta tctcaacatt ggttatgctg tttaggtata
    10561 tatgctttga aacctccctt gccgttccac catcgcctcc tccgattatc aaaacatctt
    10621 tagggtcaga agcggcaaac aaaggcaaat gcgctatcat ctcatgataa acaaactcat
    10681 ccctctctgt aaacatcacc agcccatcaa gcagcataac cctgccaaaa tcgtaagttt
    10741 ccaagatatc aagcctctga agagggcttt gctctgtgct taaaaccctt tttattttaa
    10801 atgtgaaacc acatgtgcct gtatattttt ctgtgaacca gaactctgga aaataagcca
    10861 tgtcatgctc ctcctttgtg caaaaaaata ggggttgtag cccacagact acaacccctg
    10921 aaagattaat ttaaagccaa attacttctt tgttgggccc tctgccttaa acttcctgcc
    10981 cacttctaag cccatatcaa aagccttcat gttcatatct ataaatgctg gcggaacctc
    11041 ttctttaact gtatccctaa ctgcatctat aggcaaaacc tcggtaagac ctaaacaaat
    11101 tcctacagcc aaaatgttca tagtaacaac attgcctatt tcatatttag ctgttctaac
    11161 taaaggatac tcataaactt tatacttttt agcatcatca tctggaacta caactaaacc
    11221 tgaatccact aaaacatagg catcttcctt taagtcgccc ttgtaggcat cataagcctt
    11281 ttgatgagtt gacaggaaga aatcaacatt ggttgattca gggaatgtta tgggctcatc
    11341 agaaataatg atatcagcct ttgctgcacc acccctaacc tgggatgtat atgtaggcac
    11401 ctgagtagcg taatatttgg ttctaaaaac ggctgcatgg gcaagaattg ttcctgctgt
    11461 taaggaaccc tgtccaccta ctcctccaaa tcttaattca taatgaaatg ccattttctt
    11521 acctcttcct taaagttttt tccattcttt taatggtgtt tcaacatcgt atggatacaa
    11581 tcctttcaac tcttcccttg ttatcttata tttatcggca tctgttacac tgccttttac
    11641 atattttgcc cagtattcat cgcttgcctg agccttctca accaacgcct tgtaagattc
    11701 tgtaagctct ggcttgctct catccttgtg caatacaccc atcacaaact tacccttaag
    11761 ctcttcttca ctcatcttct tagctttggc tgagcttaca aggaaacctt tcatataatc
    11821 catcaattta gcaggatcgc ccaatttgtt tcttcttcca aagttaattg gacatgggct
    11881 gaaaacctca atcaagctga aacccttata ggcaagacct tctttaataa gctttgtaag
    11941 tcttgttggg tctcctgcaa aaccccttgc aacatagcct gcaccggcac caattgccat
    12001 cttacaaaca tcgattgttg gctcaaatgt tccccttgga gctgtagatg cttttgcacc
    12061 tggaggtgtt gtacaggaat gctgaccacc agtcattccg tagatccagt tgttaatcaa
    12121 aacaactgta atatctatat tccttctgca tgcatgaact aaatggtttc cgcctatatg
    12181 aaccagatcg ccatcaccac cgaaaacgaa tacatgctta tccggatgag acatctttat
    12241 acctgatgca acagctatag cccttccatg aattgtgtgc aatgtgtgga agtcaacata
    12301 acctgtaacc cttgctgcac atccaatacc ggataccata gcacagtcat cttttttcca
    12361 acctaactca tcaatggctt caaggtagca ttttaaaacg ataccatcgc cgcaacctgg
    12421 acaccagtaa agcggcatct tttccattct taggtatttt gtgtaatcaa cagccattat
    12481 tcgcctcctc caaaccttct aatctcctca tcagtcataa caatctcgac cttcttctct
    12541 ggattcttga ttttttcaag aatctgagaa ggcctaataa gggttcctgt tgcctggcta
    12601 attccataaa cattagcagc atcaccaacg atcctttgaa cctcaagtat atactggccc
    12661 aaattcatct ctggaactat tatattctta acttttcctg caatatcttt tatctgttgt
    12721 tctggtgatg gccaaacggt tagaggtctg aacattccaa cctttatacc ttcttttctt
    12781 gcctcatcga ttgcaactct tgcagcctca gcagtggaac caaacgctat aatgcaggtt
    12841 tctgcatcgt ccatcttgta atactcatat ttcaatattt catcaagatg gtttgtaatc
    12901 ttgctatgca tcctgttcaa cagccactga acatactttg gaacaactgt tgggaatcca
    12961 gtcttatcat gaattaagct ggacatatga tatctgtagc tttttccgtc ctttgtccac
    13021 catggagcaa gaggtggaat ctcgtagtta taatcataag gataatactc atcaggttca
    13081 acatctggag cctgtctatc aacaatttca acctcttctg ggtctggaat gtaaaccttt
    13141 gtgtgcaagt gagacaatga accatctgtt aaaatataaa caggctgtct aaatttttca
    13201 gccaaattaa aagccctaat agtctcaaaa acagcttcct gtgcgttggc aggagcaata
    13261 gctattacag gatggtctcc gtgtgttccc catcttgcct gcattatatc gccctgagaa
    13321 ggccttgttg gcaatccagt tgaagggcct cccctcataa catcgacaac aacaagtgga
    13381 acctcaaaca tgcaagccat gccgaatgct tcttgcttta aggataaacc aggtccactt
    13441 gtacatgtca tagctttaac accacttgca gctgcgccaa cacaagcatt gatagaagca
    13501 atctcatctt ccatcatcat aaaaggcacg cccctttcgg gcattatctt tgatagtctt
    13561 tctggaactt cgctggaggg tgttatcgga taacccgcat aaaagcccaa tccagcaaca
    13621 acagccgcct cagctatggc agcgttagca tccataaatc caattcttcc cattgattcc
    13681 tcctacttac tttttgtaac cgtatttccc ttactatctg caaactcaag ttcaacaccg
    13741 atatcagcaa cagtaattgc aaaatctgga caaatattct cgcacatttt acatctaatg
    13801 caatcctcag gccttgctac ctttgctata gtacccatcc agacatgcaa atcctcaacc
    13861 atctctaaaa cattttttgg acaaacgtta acacacaaac cgcaaccctt acacaacttt
    13921 tcattaatct caaccggcat gcgtttttca gccatacaac ctctccttct ttaaagaatt
    13981 aagggggcac aaagccccct cacccatttt cttacagctt tgaaacaata gaatttagag
    14041 tttcactaca cctcattatc ttttcaacct tttcctcatc tggccagtaa tatccgtcga
    14101 tttcggaggg cttaccctga acaacatcaa aatcgtttat tatcttctct tcattttcct
    14161 tcatttcttt tgctataggc tcaaagattt tcttaagctc ttcatcctca ctctgctcag
    14221 ccaaagcctc agcccaatac atagcaaagt agaaatgatt gccccttgta tcaagctgat
    14281 gaacctttct acctggccat ttctgattct ctaacacctt tgtcatggcc ttatcggcag
    14341 catcagacat taccttggct ttcttgttgc catatctttc agctatatgc tcaagtgagg
    14401 caaaaatagc gccaaactca cccaaagaat cccatcttaa gtgtccttct tctattaact
    14461 gctgggcgtg ttttggggca gaaccaccag cacctgtctc aaacaaacca ccaccggcaa
    14521 gcagagggac gattgaaagc atcttggctg atgttccaac ttccaaaatc gggaagaggt
    14581 ctgttaaata atcccttaaa gcgttgcctg ttacagatat agtattgaga ccttttctga
    14641 ttctttcaag cgagaatctc atagcatcaa ctggcctcat aatcctaatg tccagaccct
    14701 ctgtatcata atccttaaga tactctttaa ctttttttat aagctcagca tcatgagccc
    14761 tattttcatc aagccagaaa acggcaggat aacctgttgc tcttgccctt cttacggcca
    14821 agccaaccca atctctgata gcctcatctt tagcctgaca acctctccag atatcacctt
    14881 tttcaacatt atgttcaatc aaaacattgc cattttcatc tacaacacgc acagttccat
    14941 tagatggagc taagaaggtt ttatcatgtg atccatactc ctcggccttc atagccatca
    15001 aaccaacatt ggaaacatcg cccattgtgg ttctgtcaaa ctgaccattc ttcttacaat
    15061 cctcaacgac ctctttatac atggtagcat aacatctatc aggaataacg gcctttgtat
    15121 cttgaagctc atcgttcttg ttccacattt taccgccatc tcttatcatt ggcggcatgg
    15181 aagcatcgat aataatgagg tttggagcat gaaggtttgt tattcctttt cttgaatcaa
    15241 ccatagcaag ctcaggattc ttttcatata ccttttctat atcagcttca atctgctttc
    15301 tctggtcttc tggtaatttt tgaattctgg cgtaaagatc tctaaggccg ttgtttggat
    15361 taacgcctaa ttctttaaac agttccttat acttctcaaa tacatctttg aagtatattt
    15421 caaccatatg tccaaagatt ggaggatcgg ataccttcat cattgtagct tttaaatgca
    15481 atgataaaag aacacccttc tctttggcgt cctttatttg ctgatcgaaa aactctctaa
    15541 gttttttaac gctcatgaag gttccgtcaa aaacctcacc ctttagtagg tgaagttttt
    15601 tcatagtttg agcattgccg ttctcatcga caaactgaat ctcaatatcc atttccctgt
    15661 ctgtcgtgaa ggacttttca tgctcataga aatcaccacc atccatatgg gcaacatggg
    15721 tttttgaatc ttctggccac ggctttagcg gcaaacccat tgaatctggg tatttttttg
    15781 caaactcttt aacagaagtt ggaagccttc tatctgagtt gccctgcctc aaaacagggt
    15841 taacagcgct tcccaaaacc ttcgcatatc tctcttttat ctctttttct ttctcatcct
    15901 ttggctcttc aggataatca ggaacgttgt agcctttctc ttgaagctct ttaatagctt
    15961 ccttaagctg aacaacgcta gcagagatgt ttggaagttt tatgatgttg gcttctggtt
    16021 tgttaaccaa ctcgcctaaa taggctaaat cgtcattgat cctctggtct tctttcaaat
    16081 actcaggaaa tgtagccaaa atccttcctg ccaaggagat atcccttact tcaacatcaa
    16141 catcggcatg cttgacgaag cctttaacta tgggtagtaa agaaaatgat gctaaataag
    16201 gcgcctcgtc agtcttcgtc catacaattg taggttttcc tgtagccatc cttccactcc
    16261 tttctataaa ttcttatttt tcactttata aatgcctcct tgcagacacc cctaaactct
    16321 gcgcaagata tacaccaatt atcaagttgt gtcaagaaat tattgatttt tcaaggcttt
    16381 aagcttgact tttttgctct cttattgcat tctttttgtg agtgaaagga gggggagaag
    16441 ttgataaatc ccaacatttt tttaatggtc ataccttttt tagtggctgt tgtttttcat
    16501 gaggtaagcc acggatatgt ggcatataaa ttgggtgata acacagccaa gtttgcaggc
    16561 aggctcacat tgaatccagt ggcacacata gacatattcg gcactattgt tctgcctgct
    16621 attttgataa tcgctcactc gcctattctt tttggttggg caaagccggt acccgtaaat
    16681 ttttttaacc taaaaaaacc caaaagagat tcggccatag ttgcagcagc aggacctaca
    16741 acaaatatac tacttgccgt attatttgct ataatctata ggattagcct gtttctccca
    16801 gcaagtttta tacaacaacc actcatgata acatgcctat acggtgtgca gttgaattta
    16861 atatttgcct tttttaacct tatacctata ctgccactcg atggcggcag gatattggct
    16921 gcattcttac caccaaaatg ggcttataac ttttcaaaac tcgagccata cggtatatat
    16981 atagtaatag ccttgctgtt tttgggtatt tttgatttta tctttacatt cttcgtttta
    17041 ccgctatcaa gcatactact gtcttaggag aaaaaaatga aagaagctta tctttattcg
    17101 agacttgagg ataataaggt tcaatgtaat ttatgttcat ttaggtgtaa gttagcagat
    17161 ggcaaaacgg gcatatgtgg tgtaagaaaa aatgaaggag gcacacttta ttctacagtt
    17221 tatgcgaggg ctgtagcaaa ggcgatagat ccgatagaaa aaaaaccatt attccacttt
    17281 ttaccatcta ctaaatcgtt ttcaatagca accgtggggt gcaattttaa ctgcctgaac
    17341 tgccagaatg cagacataag ccaatatccc aaagaaaacg caggtgctgt tgtgggtgat
    17401 gtttatccac ctgaaaaggt tgtagaagat gccatatctg caggttgtaa gtctatagca
    17461 tacacataca ctgaacccac cattttcttc gaatacgcca tagatacggc aaaattggca
    17521 aaagagaagg gactgaagaa catatttata acaaacggct atatgacaaa agaaacgata
    17581 gatatgatgg acggcttaat agatgctgcc aatgttgacc ttaaagcctt caatgatgca
    17641 ttctatatgc agatatgcgg tggagccaga ttaaagcctg ttcttgaaag catagaatat
    17701 atgaaatcca agggaatttg ggtagaggtt actacacttg ttataccaac agcaaatgat
    17761 gatccggccg aggcgatgca gatagccgag catatctaca acatagatcc atcaattccc
    17821 tggcatataa gcaggtttta tccggcttac aaattcagcg atgttatgcc gacccctcca
    17881 gaagttataa agaacttcag gcaaattggc ctatcaatag gcctaaagta tgtatatacg
    17941 ggcaacatgc tgggtgatga gggcgagcac acatactgtc caaattgcgg cgaacttctg
    18001 atagcaagat atggctatga aattctatcc tatgccataa aagatggtaa atgccccaaa
    18061 tgcgggacaa aaatagatgt ggtggagagt taaggtgagg ttgttgtttg cagaggaaga
    18121 gatagaaaaa agaatagaga aactcgcaaa gctattagat gaaaagctaa ggagtaaaca
    18181 agaaaaaacg gttatgcttt acatagaaaa aggcggcaag ccgttttttg agaagctcac
    18241 acagaagatg aaaacaaatc caatcaagga cagcatcaga gtaaaaagct acgcaggcga
    18301 tagatcaact ggaaaaatag agtggatcaa gaaaccctct gttgatttaa agggtaaaca
    18361 ctgcataatc gtggatgata tacttgacac gggcaaaacg ataaaagagg ttaaaaatta
    18421 tatgctatcc cagggtgcaa cgggttgtga gatatgcgta gcagtcaata aacacgaaag
    18481 acgagaggag gatatagagc ctgattacta tctgtttgat ttagacaaag gcttcatcat
    18541 cggctttgga atggattaca acgaaaaata cagggagtta cccgcaatat acctaatggg
    18601 tgaatcataa cagaactatc ctacagttat atgaaaaatt taaacaaaaa atgtgtcgca
    18661 ctatactcag gggggcttga cagcctactt gctatattga tagtaaaatc cttaggggtt
    18721 gaagtttatc cattattcgt tcagacaccc ttttacaata aagaaataga taaactaaaa
    18781 gaacaactaa ataagtctgg actggcattg gaaactgcaa gggatgataa ggcatatata
    18841 gagatgcttc taaacccacg ctttggttat ggtaaaaatc taaatccatg catagactgc
    18901 aaagccttct tttacaaaaa ggccaaagag tacgcggata aaatcggggc aagctttatc
    18961 ataacaggtg aggttttagg tcaaaggcct atgagtcaac gatcgtatac cgttcttcga
    19021 acaatagaaa agcatgcagg actaatagat ttagttttaa gaccgctctc tgcaaaatgc
    19081 ctcaaagaaa caatcatgga gaaggaaggc atagtggata gggataagct atactgcata
    19141 cagggcagga caagaaaggc gcaatttgag cttgctaaaa ccttcggtat tgaggagttt
    19201 gaaagtccag ccggtgggtg tttgctaact gatactcaat ttagtgcaag actaaaagag
    19261 atgctcgata aaaaggatga actgaacagt ccagtggcta ttgaactatt aaaaataggc
    19321 aggcacttca gggttgatgg atttaagttt atcgtatcga ggaatgcgga agaaacaaag
    19381 tttttgactg ataatttttc tgacctgcca cagataagat gtctgaacag cccaggtggc
    19441 gttggcgtat ttttaaaaga accccacata gagacaatca taaccgcagc tgcaatacta
    19501 aagagatatt caaagaaagc ccaaaacctg atatttaaag gctcaaggga gtttataata
    19561 gatgttaagc cgatgagcga tgagagactg aacagctata gagttggagg agataatgct
    19621 taaagaaaaa cttgaagaat tagaggaaaa atataaatac atagaaactc aactctcaga
    19681 tccaaatgtt gtaggcgatc tggataggta caaatcgctt agctcagaga taaaaaaact
    19741 tacacccatt gtagaaaaag ccaaagaata cagaaatatc ctaaggcaga ttgaggaaaa
    19801 tgaagagctt cttgaggatg aagagttaaa agaattggca aaagaagaat taaaacacct
    19861 aaaggaacgt ctacctgagc tcgaacaaga aataaaactc ctattgctcc ccaaagatga
    19921 ggccgacgat agggatgtaa tattggagat aagggcagga acaggtggcg aggaggctgc
    19981 tttatttgca gcagacctgt ttaggatgta ttcaagatat gcagagaaca agggcttcaa
    20041 ggttgaggtg ttaagcaaaa gcctatccga tacaggtggc ataaaggaga taatagccga
    20101 gataaaaggc aaaggagcct atcatctatt caaacacgaa agcggcacac atagggttca
    20161 aaggatacct ataacagaat cacagggcag aatccataca tcggctgcaa ccgtcgccgt
    20221 attgcccgag gcagagaatg ttgatgttga gataaagcca gaggatttga gaatagatgt
    20281 gtttagagcc agtggacacg gtggacaaca tgtaaacaca accgattcag ccgtaagaat
    20341 aacccacctt ccaaccggta tggtggttag ctgccaggat gagaaatctc aacttaaaaa
    20401 caaggaaaaa gcgctaaaga tactcaagtc aaggctttat gatttttaca ggcgtaaaaa
    20461 ggatgaagag agggccaaag agagaaaaag tcagataggc tcaggcgata gatctgaacg
    20521 cataagaaca tacaatttcc ctcaaggtag ggtaacagac cataggataa acctaacatt
    20581 atacaagctg gatagtataa tggagggaga tctggatgag ctaatagagg cattaatcgt
    20641 agatgaacag gcaagaaaac taaaagaaag cggaatgtga gggaaaaatg ggatttaaat
    20701 gcggaatagt gggtcttccc aatgtgggta aatccacaac attcaatgcc ttaagcaggg
    20761 gcaatgccga aagctccaat tttccattct gcacaattga accaaatgtg ggcatagccg
    20821 aggttaaaga tgaaagactg tataaacttg cagagttagt aaaccccaag aaaatcacac
    20881 ctgctgttgt ggagtttgtt gatattgcag ggcttgtgaa gggtgcaagc gaaggtgcag
    20941 gattgggcaa taggttttta agccacatca gggatgttca ggttatcgtg catgtggtta
    21001 ggtgttttga ggatgaagac atcgtgcatt cggttggcga ggttgacccc aaaagggata
    21061 tagaaattat cgacacagag cttatgcttg ccgatctgca aaccatagaa aacagggaaa
    21121 acaaaacact taaaatagca aaaagcggcg acaaaaaggc caaagccgag cttgagatac
    21181 tggagaggtt taaaaacctg cttgagagcg gaaaacctat aaggagtgaa agcctaaagg
    21241 cagaagaggt ggatttagta aacgagttaa ggcttctgag cgcaaaacct gtgatatatg
    21301 tggccaatgt atcggaggat agcttagatg gtaatgaata ctcagaaacc gttaaacaga
    21361 tagcaaacaa ggaaaatgca ccggtcatag tgctttcaag caaggttgag gaggagttat
    21421 ccagactgtc tgagcaggaa agaaaagagt ttatggagat gttaggctta aaagaatcag
    21481 gccttgatag gcttgcaaag gtaggctatc agatgctcgg tctaataaca ttcttcacag
    21541 ccggaccaaa agaggttcgt ggctggacga taaagaaagg aacaacggca aaagaagctg
    21601 caggtgtaat acattccgat atagaaagag gattcataag agctgagatc ataaaatacg
    21661 aagattacat agccgcaggg ggcgaaaagc aggccaaaga aaaaggctta atgcaccttg
    21721 agggcaagga ttatatcatg gaagatggcg atgtagttta tttcaggttt aatgtatgag
    21781 ggttataagg gacatatacg cagagtgcga tatagaagca acggctatag cgttaggaaa
    21841 cttcgatggc atccacaggg ggcatcaagc acttattaat gaaacggtca agctaagcaa
    21901 aaaactaaat ctaacacctg cagtattcac ttttcatccc cacccaaaaa aggtcataga
    21961 gcacatagat gaaccgttct taattcagag atttaaggag aaaacaaaaa tcatagagag
    22021 cttcggtata gatatagttg tttgtgccca ctttacgcaa gcatttgccg agatggagcc
    22081 gtataatttt gtaaaagaca tactcataga cagaatgcat gcaagggcaa tatgtgtggg
    22141 acacgattac acattcggca aaaaggctct tggaacaaca aaaacattaa gggagttatc
    22201 caacagtctt ggttttgaac ttatcgtaat acctccgttt aaaatcaacg gcacaatagt
    22261 aagctcaaca aggataaggg aatttttaag gacaggtcaa atcggattgg ccaatgagtt
    22321 tttgggcagg aattacacca tatccggtat cgtaaaagag ggcgaagggc gaggctcatc
    22381 gcttggtttt cccacggcaa acatctatcc aacaaacgag atactcctaa caaacggtgt
    22441 ttatgcagcc tatgtttaca tagactcaaa gaagtatgcg gctgctgtta atgtgggcgt
    22501 caatccaaca ttcaaaggca cacaaaagca catagaggcc tttatctttg attttaacgg
    22561 tgacttgtat cgaaaaagga taacaatcga gtttatagat tttataaggc cagagagaaa
    22621 attcaaaaga atagatgatc tgataagcca aataaaacag gatataaaac agataaaaac
    22681 aatcctttag gagaaggcga tggtttttga aagcttgggc gaatacatag aggctcttaa
    22741 gaaaaaaaag gagctgttga ttataaaaga tcaggttgac cctgtttatg agatgggata
    22801 catagcagat agactcataa aaagcggcgg tcctgcggtt ctgtttgaaa accccaaagg
    22861 cagcggcata cctgttgtaa tgaacctgtt tggcacaaga aaaagaaccg agtttgcctt
    22921 aaatgttgaa agccttgacg agttgggcag cagggttgag gagcttgtaa atgccgaggt
    22981 gccctataat ttctgggata agctaagaaa catagtaaaa cttaaggagt ttagcaaatt
    23041 tatacccaaa atcgtctcct atgccccatc gcaggagata atcatagaca acccagacct
    23101 aaccaaactg cccatcctaa agacatggcc gatggatggt gggcgtttta taaccctgcc
    23161 gcttgtattt acaaaaaatc ccaaaacagg caagcagaac tgcggcatgt atagaatgca
    23221 ggtgtttgat aaaaacacaa ccggtatgca ctggcatatc cacaaagatg gagcgcacca
    23281 ttataggtgg tataaagaga aaaaccagaa gatgccggtt tgtgttgcaa taggcgcaga
    23341 ccccataacc atatacacag caacggcacc actgcctgag gatatagacg agatgctgtt
    23401 tgccggtttc ctgcgcagaa agcccgtaaa actaaccaaa gccacgcttt cagatatact
    23461 tgttcctgcc gaggcagaga tcatacttga gggatatgtt gatcccaatg agcctttgca
    23521 catagaaggt ccatttggcg accacacggg gtattactcc ttagctgatt attaccctgt
    23581 attccacata gagcggataa caatgagaaa aaaccccata taccctgcaa ccatagtggg
    23641 caaaccgccg atggaggact gctttttggg taaggccaca gaaaggctgt ttttgccgat
    23701 aattaagaaa atattgccag aaatcgtcga tataaacctg cccgttgagg ggatctttca
    23761 caactttgcg tttgtctcca tcgataaaca gttcccaggc catgcattca aggtcataaa
    23821 cgccttatgg ggattgggca tgatgagtct aaccaagata atcgtgatat tcgacaaaca
    23881 tgtgaatgtc caggacatat cggaggttat ctggagattg ggcaataaca tagaccccaa
    23941 aagggatatc atatt
//
