LOCUS       c00024_NZ_SRYR..       24991 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_SRYR01000004.1 Clostridium sartagoforme strain NM50_B9-20
            NODE_4_length_250243_cov_397.304, whole genome shotgun sequence.
ACCESSION   NZ_SRYR01000004
VERSION     NZ_SRYR01000004
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:01:56
            Original ID  :: NZ_SRYR01000004.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 165971
            Orig. end    :: 190962
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24991
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[175971:180962]"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14991
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
     cand_cluster    1..24991
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /kind="single"
                     /product="acetate2butyrate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24991
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="acetate2butyrate"
                     /region_number="3"
                     /rules="(not (POR or POR_N or PFOR_II) and minimum(4,
                     [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF, ETF_alpha,
                     HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and minimum(1,
                     [EC1_2-faecali, ECH1_Enoyl_CoA_DH1, ECH1_Enoyl_CoA_DH2,
                     ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4, Thiolase_C]))"
                     /tool="gutsmash"
     CDS             87..2522
                     /locus_tag="ctg24_166"
                     /transl_table=11
                     /translation="LKDKYKISGMTCSACANRIEKGVSKMEGVKEANVNFATETLNVEY
                     DDLALKPLDIENKVEKLGYKVEKNIESHNYKIEGMTCTACASRVEKVTNKMPGVENAVV
                     NFATEKLSISFDADKVTFGEVKATVEKAGYKLIREEDNVNNEGKKVTEQSKLLKRLILS
                     LVFTVPLLIITMGHMVGMPLPEIIDPMMNPLNFAIIQLVLTLPVVLTGYKFYSIGYRNL
                     FKLSPNMDSLIAIGTSAAFIYSLYGTYKIYMGDAHFAMMLYYEASATILALITLGKYLE
                     AVSKGKTSQAIKKLMGLAPKTATIVRNGKEIVLPIDEVIVGDIVIVKPGEKLPVDGEVV
                     EGNTSVDEAMLTGESIPVEKNVGSKVIGASINKTGFIKYKATKVGKDTALSQIIKLVED
                     AQGSKAPIAKMADIISSYFVPIVIGLAIFASIAWLIAGETGTFSLTIFIAVLVIACPCA
                     LGLATPTAIMVGTGKGAEYGVLIKGGEALEVTHQIDTIVFDKTGTITEGKPVVTDIVTK
                     NISKDDLLVLAASSEKGSEHPLGEAIVKGAEEKNLTLKDISNFNAIPGHGIQVEIEGKT
                     ILLGNKKLMVGNSIEIGDLGDESDRLANEGKTPMYIAIDNKLEGIIAVADTVKSSSNEA
                     IENLHKMGIKVAMITGDNKKTADAIAKQVGIDIVLSEVLPEDKANEVKKLQEKGSKVAM
                     VGDGINDAPALAQADIGIAIGTGTDVAIESANIVLMKGDLRDVSTAIKLSKATIRNIKQ
                     NLFWAFGYNVLGIPVAMGLLHVFGGPLLNPMIAAAAMSLSSVSVLTNALRLRGFNPNK"
     CDS             2787..2996
                     /locus_tag="ctg24_167"
                     /transl_table=11
                     /translation="MKKKILIEGMSCNNCVAHVTEALNELDDSKNIEVNLNGKYALVET
                     NVKDDIITEKIEDMGYDVVKIENI"
     CDS             3193..4266
                     /locus_tag="ctg24_168"
                     /transl_table=11
                     /translation="MGTEKKRDFIINVIYILIVGAVLYITLKYALGWFLPFVIGFGIAF
                     ILKPLINLITKKLKIKRKVVAGLTVLVFYATVGALFTLLLFKLGLVMKDLFIKLPSIYL
                     NTIEPLIYELAAKVEDILVNLDPALLEAIKQAITSIADSLGSIISSVSSGAVSFITSTV
                     SVVPSFFIILIFSIISSFFFAMDYEKITSFVIRQFSPKGREIVLDIKEYIVGTLFKIIK
                     AYSILICITFIELSIGLSILRVESAISIALLIACVDILPVLGTGGIVIPWIFIELFKGN
                     TALAIGLTIVYVVITVIRNILEPKIVGEQIGLHPLIMLICMFVGVKFFGVLGLFVLPII
                     MIILKNLNDSGKIHIFK"
     CDS             4297..4725
                     /locus_tag="ctg24_169"
                     /transl_table=11
                     /translation="MEIEFYESGSIDNEKLLYAIVVSRYNGKWVFVRHKERSTWEIPAG
                     HREENEDINCTAKRELFEETGAKEYEITYICDYSLKIKENKSYASLFFAEIEKLGELPD
                     YEIGEVGFFDEIPKNLTYPNIQPKLHNKVKEEINKFVF"
     CDS             4777..5370
                     /locus_tag="ctg24_170"
                     /transl_table=11
                     /translation="MMMNTHKALAQGFINGLEDDKVFIISSGHFIWGNLKPDSASKYKF
                     KKHYFDESFDMIVKKIEFLSSLTLDDIYIRYSIGKFNQELGVVCHFLCDYFCVPHFQRW
                     EFKSPGAVKDHVLYENDLNKYAKLCTIRQDINTSLKSEDIRKYIENLQKEYDGNVSYEK
                     DLVYASHICNTVINLILDEVILNQKLKEHIALVI"
     CDS             5694..6053
                     /locus_tag="ctg24_171"
                     /transl_table=11
                     /translation="MGENKLESCNCTIIHKDVVERVKENLPEEEILYDLADLFKAFSDS
                     TRIKILHALFQEELCVCDLAALLEMTQSAISHQLRVLKSNKLVKFRRDGKVIYYSLADD
                     HIKHIFHEGFKHILE"
     CDS             6069..8312
                     /locus_tag="ctg24_172"
                     /transl_table=11
                     /translation="MSNKDIKLVLSGLTCANCANKIETRVNNLDGVKEANLNFTTSTLV
                     IEGDGSKEEDELIVKAKEIINKLEPEVKVYNKDEVKEPIRNTSSCADGRCAIDDGSHDK
                     DSHNHHSHGDSHEHSHEDGHDHSHGHDHSHNEPITLKENIPLILGVIIYAIAVVFRNES
                     LLNGVLFVVSYLLIGGKVLTTAIKNIFRGEIFDENFLMTVATLGAFFVGEYPEAVAVML
                     FYEVGELFQSYAVNRSRKSITSLMDIRADYANVIRNGVEEKVNPETVNIDEEIIVRPGE
                     RVPLDGIVIDGTSFVDTSALTGESVPREISINEEILAGCINTNGVLKVKVSKNFKESTV
                     SRILELVENASNKKAPTEKFITRFARVYTPIVVFLALALAIIPPLVIKDATFNEWIYRA
                     SIFLIVSCPCALVVSIPLGLFAGIGGASRRGILVKGGNYLEALKNVDSVVFDKTGTLTK
                     GVFKVTEINNVNIEKGELLKVAAIAESNSNHPIAQSIIKEYGKDVTSSEIKDYEEISGH
                     GIKTTIDGLEVLIGNYKLMEKFNIAYNKVDSIGTIVHVAISKEYKGNIVISDEIKETSK
                     EAISGLREIGVRQSVMLTGDNKVVADKVSDIIGLDKVYSELLPGDKVEKLEEIINNNKS
                     EGKVIFVGDGINDAPVLARADIGVAMGGIGSDAAIEAADVVLMKDDPKALVDAIKVARK
                     TNKVLWQNITLALVVKVLVLGLGALGMANMWEAVIADVGVTVLAVINSTRCLK"
     CDS             9163..9807
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CoA_binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg24_173"
                     /sec_met_domain="CoA_binding (E-value: 3.2e-23, bitscore:
                     76.1, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKKNISMAVIKRLPKYHRYLQELLKNDVDRISSKELGEKIGFT
                     ASQIRQDLNCFGDFGQQGYGYNVKDLYNQISLILGLNKEYKGIIIGAGNIGQAIANYSR
                     FSQVGLNIGAIFDANPKLIGMRIRDIEIEDIDLLKNYLRENIVDIGIICVPRINAQKVC
                     DVLVENGVTGIWNFAPVDLSVPENVTVENVHLSESLLTLIYLLHDKDESNL"
     CDS             10001..10783
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: EC1_2-faecali"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_174"
                     /sec_met_domain="EC1_2-faecali (E-value: 3.5e-89, bitscore:
                     292.2, seeds: 67, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELKNIILEKSEHLAIVTINRPKALNALNSETLKDLDVVLDDLEK
                     DNNIYCVILTGSGEKAFVAGADISEMKDLSEEEGRNFGLLGNKVFRRLEKLDKPVIAAI
                     SGFALGGGCELAMACDIRIASEKAKFAQPEAGLGITPGFGGTQRLPRLVGEGKAKELIY
                     TCATIKADEALSIGLVNKVVPLESLMDEAKAMASLIMANAPIAVKLCKDAINRGMQVDI
                     DKAVEIEAGDFGKCFATEDQKEGMTAFMERRAKNFSNK"
     CDS             10872..12011
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_175"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 4.4e-56, bitscore:
                     183.1, seeds: 49, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.3e-27, bitscore:
                     89.7, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1e-36, bitscore:
                     119.9, seeds: 796, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFQLTREQELVKQMVREFALNEVKPIAAEIDETERFPMENVEKM
                     AKLGMLGIPFSKEYGGAGGDTLSYIMAVEELSKVCGTTGVIVSAHTSLCASLIDQFGTK
                     DQKEKYLTDLATGKKLGAFGLTEPGAGTDAAGQQTVAVKDGDNYILNGSKIFITNGGVA
                     ETFIIFAMTDKSKGTRGISAFIVEKDFEGFSIGKKEEKLGIRASSTTELVMSNCIVPKE
                     NLIGQEGKGFGIAMKTLDGGRIGIAAQALGIAEGAFEEAVNYMKERKQFGRPLSAFQGL
                     QWMIADMDVKIEAAKHLVYKAAWLKDNKLPYSVEAARAKLYAAEVAMDVTTKAVQIFGG
                     YGYTKEYPVERMMRDAKITEIYEGTSEVQKMVISGSALR"
     CDS             12027..12806
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 177.9;
                     E-value: 5.9e-55)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_176"
                     /sec_met_domain="ETF (E-value: 2.1e-54, bitscore: 177.9,
                     seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIVVCLKQVPDTTAVKIDPKTGTLIRDGVPSIINPEDKHALEAA
                     LTIKDNNGGKVTVLSMGPPQAKNALREALCMGADEAILITDRAFAGADTLATSKALAGA
                     LKKLEYDIVFAGRQAIDGDTAQVGPEIAEHLDIPQVTYVQDVKVEEDGLLVNRALEDGY
                     ELIKVKAPVLLTAIKELNEPRYMNVQYIFDTANKEIQIWSADDIDVNKEELGLKGSPTK
                     VKKTMTKETKGAGEIINEVPQEAAKYVLAKLKEKHYI"
     CDS             12827..13834
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF_alpha"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 169.9;
                     E-value: 1.7e-52)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_177"
                     /sec_met_domain="ETF (E-value: 6.2e-52, bitscore: 169.9,
                     seeds: 129, tool: rule-based-clusters)"
                     /sec_met_domain="ETF_alpha (E-value: 7.8e-39, bitscore:
                     125.5, seeds: 511, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIADYKGVWVFAEQREGELQKVSLELLGEGKKIADKLGVKLTAL
                     LIGDNVKGLADTLGRHGADEVLVAENKGLKHYTTDGYTKVICDLANERKPGILFIGATF
                     IGRDLGPRVAARLSTGLTADCTVLDVDVEKADLLATRPAFGGNLMATIACPDHRPQMAT
                     VRPGVFSKLADEDRKFTVEEVAVELKDSDIRTKIVEIVKETKEIVDISEANFIVAGGRG
                     VGAKENFAILEELAEALGGTVAGSRAAVENGWIERDYQVGQTGKTVRPNIYIACGISGA
                     IQHVAGMQDSDLIIAINKDASAPIMQTADYAVVGDLLKVVPEMTAQLKAMKENE"
     CDS             14149..14991
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_178"
                     /sec_met_domain="HCDH (E-value: 5.7e-38, bitscore: 123.3,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH_N (E-value: 4.9e-70, bitscore: 228.9,
                     seeds: 60, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKIFVIGAGTMGAGIVQAFAQKGYEVIVRDIKDEFVERGINGIN
                     KGLTKLVAKGKITEEDKEAILGRISGTTELALAEDCDLVIEAAVENMEIKKSIFAELDG
                     ICKESTILASNTSSLSITEVASATKRPDKVIGMHFFNPAPVMKLVEVIRGIATSQETFD
                     AVKELSVAIGKEPVEVAEAPGFVVNRILIPMINEASFILQEGIASVEDIDTSMKYGANH
                     PMGPLALGDLIGLDVCLAIMDVLYNETGDSKYRASSLLRKYVRAGYLGRKTGRGFYTY"
     CDS             15554..16495
                     /locus_tag="ctg24_179"
                     /transl_table=11
                     /translation="MNFDKVSFEDNKVILEGLKNFDIKQILECGQCFRWDKISDTNYII
                     VAYGRVIEVLQEGDKATIYNSNEEDFNNIWINYFDLERDYDEIKTELAKDEILQKSVDF
                     GYGIRILNQDPFEMLISFIISARNSIPSIKKTVKKICEAWGERIEYKGVEYYTFPTAKA
                     IKEATLEDIQGTGASFRSKYIVDTIKKVNEAIEVKEDMENNPDKYSERPEILDFDLEYI
                     KSLNDDECHVALQKFMGVGAKVADCIMLFSMAKHSAFPVDVWIKRAMIYFYVAPDVSLN
                     KMRVFARDKFGAYSGMAQQYLFYYARENKIEV"
     CDS             17165..23839
                     /locus_tag="ctg24_180"
                     /transl_table=11
                     /translation="MKRKMIAAKLTALALTTVFASGLMIQSVSAYEISVGTNLATENII
                     SEQKANDYKVIGGVKDVIQSENKVTFEMTTGEKIRVSILENDVLRIYMDPKGEFQEDPT
                     PNSKDHIAKIIDKQESEYSNVTPVLEMGNTIKVSTEVIELRVDKATGKMELFNKKTNSL
                     VWKEAEPLKYKDTETIQTLEASEDEYFYGGGQQNGRFSHKGKVINIKNENNWVDGGVSS
                     PTPFYFSTKGYGVMRHTFKPGQYDFEATEEGKMTAKHDEKRFDAYYFIDEKPTDIINKF
                     TELTGKPILLPEYAFYLGHANAYARDWINDETGQESQTPKPGFDRQETLMVDAKKVVDE
                     HIDNDMPLGWFLPNDGYGAGYGRADTIDGNIALLKEFVDYTKSKGIQTGLWTQSDLKPT
                     GVGEVYLQRDIDKEVGEAGTNAVKTDVAWVGAGYSFALNAVRQAAEGIVNNSVDRARPF
                     IVSLDGWAGTQRYASIWSGDQYGGNWEYIRFHIPTYIGSGLSGQPNVGSDVDGIFGGNK
                     LIQTRDIQWKAFTPVEIDMDGWGSNPKKPYIFGEPYNSINRMYLKLKAEMMPYNYSIAN
                     EATNDGVPMVRAMMLEYPEAYTYGTNTEYQYMWGPNLLVAPIYQDTASDSAGNDIRNDI
                     YLPDEDQIWIDYFTGQQYRGGGVLNNFDAPMWKLPLFVKNGAIIPMANENNTPEDIDDS
                     QRKFEVYPSGDTSFEMYEDDGLTTDYYEGKSATTMITSSAPKTGKGKAVIKAGLLTGSY
                     EGIVTERSTEFTVNVSEKPTDLSLKVGNENVDLKEAASLEEFEKGTNLYFYDESPNLNK
                     YSTEGSEFADVDITTTPKIYVKVDKTDVTVNEVELTINDFINTQDISKNEVNKDLKAPK
                     NFEAPEDLITSSSIDLTWDKVKDAESYEIEIDGIIQRNITSTEYSHKGLDFDTEYSYRI
                     RSVNKDGYSEWSKELTARTDLDPYRNVPKDMTVKWTEGQYSSDVPANAVDGDDNSQFHS
                     KGNAIDVPFIIDMKKAYQIEKLELLFRNAGNGSVKRAEIYSSLDGVNYQKVFSNASDSG
                     NAAWTTDGQVKTIGFDAPIKARYFKIVTKESVGNFLTMREFRPYMVDGSKGQLVGDWNN
                     GGTIEEGDLTFLQNYTGLSSVDADWDYVSMADLNFNNVIDAYDISYVASQLEGGIVPTE
                     GGNVAGEIMLVPNKASISAGETFTVDVVGTGLSDVNAFSAEIPLDSSKYEFVKTEGAVS
                     TASMKNFSKIRLHSDNSQDLYTVFTNIGDNVRLNGTDTLATITLKAKSDINFDLALSDA
                     LVVDSNLNSKNAVANITNPEDPLPGDKDSVVKIGKESITVTGDESQLQTGMGLSRLIDG
                     TTSSDDSSRMDLKWVYSADQADKGKLPFEMTFTFKEAKKFNNFTIYNRTNADGKNNIAA
                     MKKVKAVGYLNGVATDLGEVSNITTAKTIFNLEGKSFDKIVITALESNKDMYTLAINEI
                     EFYEEKQQAPSSIEFLENAPTNLYVNKIAPIFAKVLPETANLNYKLTSDNEEVVKVIRV
                     DNGNSSTYYLRGVKPGTAKVTATTVDGKLSDLHEVTVLDGFDKSILIEAIEKGKSYSKN
                     SEIYTEETYSELLKAIENAEKVLESAKTESELSSAIISIRVAINGLKEREEPNLNVIDF
                     NKLEAIFATTEADSDFMENAVDGDENTIWHSGYQSKDKLPVSIVVKLDKPYNLNQVDYL
                     PRQNSRNGHVTEYIVETSLDNENWTEARRGTFKEASNGSGLENKGYNPIRFNTTKAQYV
                     RFTALKTLGDTRDKYASAAELKFYGQSEVDKSNLSAKISEAEALVEADYTAESFEAVKV
                     AIDGAKVILNDNLATQEQVDEAISILTDAIDNLVKKDDVEEVNKTVLAMAIEYVQNLKA
                     NGELEDVVPAVIKELEAALEEAKEVLANENATQAQVDVAEKRLINVIHMLEFKKGDKTK
                     LKELVEIIKVLDESKYTTSTWNALQVELEKADKVIADENAMEKEVAKTYESLNKAFAEL
                     ELVADNSKLAQLVAELEGKDLSKYTTGTVNKFKAELEYAKGILSNKDASQEEINEAYNK
                     LIKAYLDLRLIPDKSLLEDLISKAESIDLSKYTKESANKLSLALANSRSILNKEEVTQN
                     EIDESADELKSALEGLIASNGNGNGNNNGNNGGGNGNNNGNNGSGNGSNNGNNGSDNGN
                     GNGNGSGNNNSNGNGNNNSNNGGKLPSTGGTPAGAIALFGVLTSALGVSIFKKKK"
ORIGIN
        1 ataccacccc ctgggggtgg gggtaaaaag aatagaaatt atctttttat ataaaatata
       61 attatgatct aaaggagatg aatgctttga aagataaata taagataagc ggaatgacct
      121 gttctgcatg tgcaaataga atagaaaaag gtgtaagcaa gatggagggg gttaaagaag
      181 caaatgttaa ctttgcaact gaaactttaa atgtagagta tgatgattta gcgcttaagc
      241 cattagatat tgaaaataag gttgagaagc taggctataa ggtagaaaaa aatattgaat
      301 ctcataacta taagatagaa ggaatgacat gtactgcctg tgcaagtaga gtggaaaaag
      361 ttacaaataa aatgccaggt gttgagaatg ctgtagttaa ttttgcaaca gaaaagttat
      421 caataagctt tgatgcagat aaagtaactt ttggagaagt taaggctact gttgaaaaag
      481 ctggatataa gctaataaga gaagaagata atgttaataa tgaaggtaaa aaagttactg
      541 aacaaagtaa gttattaaaa agattaatat tatcattagt atttacagtt ccactactaa
      601 taataacaat gggccatatg gtaggtatgc cactgccaga aattatagat ccaatgatga
      661 atccattgaa ctttgctatt attcaattag tattaactct tcctgtagtt ttaacaggat
      721 ataagttcta ttctatagga tatagaaatt tattcaagtt aagtcctaat atggactctt
      781 taattgcaat aggaactagt gcagcattta tttatagcct ttatggaacg tataaaattt
      841 atatgggtga tgcacatttt gcaatgatgt tatattatga agcatcagca acaatactag
      901 cattaattac tttaggtaag tatttagaag ctgtttcaaa agggaagaca tctcaagcaa
      961 ttaaaaagct tatgggatta gctccaaaga ctgcgactat agttagaaat ggtaaggaaa
     1021 tagttcttcc aatagatgaa gttattgttg gagatatagt tattgttaaa ccaggtgaaa
     1081 aattaccagt tgatggtgaa gttgttgaag gaaatacatc agttgatgaa gctatgctta
     1141 caggggaaag tattcctgta gaaaagaatg tcggaagtaa agtaataggt gcaagtatta
     1201 ataaaacagg atttattaaa tataaggcaa ctaaggttgg taaagatact gcattatctc
     1261 aaattattaa gctagttgaa gatgctcaag gttcaaaagc tccaattgca aagatggctg
     1321 atataatatc atcatacttt gtaccaatag taattggtct tgctatattt gcaagtatag
     1381 cttggttaat agctggagaa actggaacat tttcattaac tatatttata gcagttttag
     1441 ttatagcatg tccatgcgca ttgggtcttg caacaccaac agctattatg gttggaacag
     1501 gaaaaggtgc tgagtatgga gtattaatta aaggtggaga agccttagaa gttactcatc
     1561 aaatagatac tattgtattt gataagacag gtacaattac agaaggtaaa ccagttgtaa
     1621 ctgatattgt tacaaagaat atatctaagg atgatttatt agtattagct gcaagtagtg
     1681 aaaaaggttc agagcatcca ttaggagaag ctatagtaaa gggtgcagaa gaaaagaatc
     1741 ttacattaaa agatatatct aactttaatg caattcctgg acatggaatt caagttgaga
     1801 tagaaggaaa aactatatta cttggtaata agaagttaat ggtgggaaat tctatagaaa
     1861 tcggagattt aggagatgaa tctgatagat tagctaatga aggtaagaca cctatgtata
     1921 ttgcaataga taataaatta gaaggaatta tagctgttgc agatacagtt aaatcaagta
     1981 gtaatgaagc aattgaaaat cttcacaaga tgggaataaa ggttgcaatg attactggag
     2041 ataataaaaa gacagctgat gcaattgcta agcaagttgg aatagatata gtattatctg
     2101 aagtattacc agaagataag gcaaatgaag tgaaaaagct tcaagaaaag ggtagtaagg
     2161 tggcaatggt tggagatgga atcaatgatg ctccagcatt agcacaagct gatattggga
     2221 ttgccatagg aacaggaaca gacgtagcta tagaatcagc taatatagtt cttatgaagg
     2281 gcgatttaag agatgtatct acagctatta aattaagtaa agcaactatt agaaatataa
     2341 aacaaaactt attttgggca tttggatata atgttttagg aataccagta gctatgggat
     2401 tattacatgt atttggtgga cctctattaa acccaatgat tgctgcagct gcaatgagtt
     2461 taagttcagt atcagtatta acaaatgcac taagattaag aggatttaat cctaataaat
     2521 aaatcaataa gtagtcttta acatattacg ctcggcctcc gtcgcaagct ccaagtcggc
     2581 ttacgcataa tatgttaaag actccttgaa taatttaatg gtgcagaagc aagtatgcta
     2641 aaggaagaaa ttcagacgag ctgaatttca atgattgtag ttgcatatat aaagaattgt
     2701 aatagataat tgtacgaata ttttatttat atttactaga atttatcatt atttaaaata
     2761 attaattagt taaggagaaa tgaaggatga aaaagaagat tttaattgaa ggaatgagtt
     2821 gtaataattg tgtagctcat gtgactgaag cattaaatga gttagatgat tcaaagaaca
     2881 tagaagtaaa tttaaatgga aaatatgcat tagttgaaac aaatgtgaaa gatgatatta
     2941 taacagaaaa gatcgaagat atgggatatg atgttgttaa aatagaaaat atttaagagg
     3001 aaataaaggc tgatattcat tagagtatca gcctttttaa gtggatatac tataggtatt
     3061 aatattttta agtattattt aagaaatgaa aatgtatttt aataaaattt aggtgtataa
     3121 tcaaataaaa accttaataa gttggaaagt tagaaacatt taaataattt attattatgt
     3181 aaggagagga atatggggac ggagaaaaag agggatttta taataaacgt aatttatata
     3241 ttaattgtag gtgctgtttt atatattaca ttaaaatatg cattaggatg gttcttacct
     3301 tttgtaattg gatttggtat agcatttatt cttaagcctt taattaattt aataactaaa
     3361 aaattaaaga ttaagaggaa ggttgtagct ggattaacag ttttagtttt ttatgccaca
     3421 gttggagctt tatttacact attactattt aagcttggat tagtcatgaa ggatttattt
     3481 ataaagctac caagtattta tttaaatact attgaacctt taatatatga gctggctgcc
     3541 aaggtagaag atattttagt taatttagat cctgcattac ttgaagctat taagcaagct
     3601 ataacatcaa tagctgattc tttagggtcc ataatttcaa gtgtatcttc aggagctgtt
     3661 tcatttataa cttcaacagt ttctgtagtt cctagtttct ttattatatt aattttctct
     3721 ataatttcat ctttcttctt tgctatggat tatgagaaaa tcacgagttt tgttataaga
     3781 caattttctc ctaagggaag agaaattgta ttagatatta aagaatatat agtaggaact
     3841 ttatttaaaa taataaaggc ctattcaata ttaatatgta taacatttat agaactatct
     3901 attggactat ctatacttag ggtagaaagt gcaatctcta ttgctttatt aattgcttgt
     3961 gtagatatac tgcctgtcct tggcacaggg gggatagtaa tcccttggat atttatagag
     4021 ctatttaaag gaaatacagc cttagcaatt ggattaacta tagtttatgt tgttattaca
     4081 gttattagaa acattcttga acctaaaata gttggtgaac aaataggatt gcatccatta
     4141 attatgttaa tttgtatgtt tgtcggagtg aagttttttg gagtcttagg attatttgtg
     4201 ttaccaataa taatgataat attaaagaat ttaaatgata gtgggaaaat acatattttt
     4261 aagtaatatg tatttagaga aatgttagga gcgagtatgg aaatagaatt ttatgaaagt
     4321 ggtagtattg ataatgaaaa attattatat gccatagtag tatctagata taatggtaag
     4381 tgggtttttg taaggcataa ggaaagaagt acttgggaaa taccagctgg ccatagagaa
     4441 gaaaatgaag atataaattg cacagctaaa agagaacttt ttgaagaaac aggagcaaaa
     4501 gaatatgaaa ttacatatat atgtgattat tctttaaaaa ttaaagaaaa taaaagttat
     4561 gcttcattat tctttgcaga aatagaaaag ctaggtgaat tgccggatta tgaaataggt
     4621 gaagttggat tttttgacga aattccaaaa aatcttactt atcctaatat tcaacctaag
     4681 cttcataata aggtaaaaga agaaataaat aagtttgtat tttaatatat atagtattat
     4741 tattaaaata taaagaacaa atggggtgag taagttatga tgatgaacac tcacaaagct
     4801 ttagcacaag gatttattaa tggacttgaa gatgataagg tatttattat tagtagtggt
     4861 cattttatat ggggaaattt aaaaccagat tcagcatcaa aatataaatt caaaaaacac
     4921 tattttgatg agagttttga tatgatagtt aagaagatag aatttttgtc ttcattaaca
     4981 ttagatgata tttatataag atattcaata ggaaagttta atcaggaatt aggagttgta
     5041 tgccactttt tatgtgatta cttctgtgta ccacattttc aaagatggga atttaaaagt
     5101 cctggtgctg taaaggatca tgtactatat gaaaatgacc taaataaata tgctaagctt
     5161 tgcacaataa gacaggatat taatactagt ttaaaatcag aagatataag aaaatatata
     5221 gaaaaccttc aaaaagaata tgatggtaat gtttcttatg agaaggacct agtatatgca
     5281 agtcatatat gcaatacagt aattaactta atattagatg aagtaatttt aaaccaaaag
     5341 ctaaaggaac atattgcttt agttatatag ttaaaaattg aaataaaata tataagatta
     5401 gaagctcaga atttctgggc ttcttttttt atatttatta tttatgggat atatggaaaa
     5461 gcgtatatct tagaaaaaag ctgagaaaat agtaagatta tagatctctc tttttttaat
     5521 aatattagta attttaaccc tagaatagtt tctatttaga tacaaaatat aagagtaaat
     5581 attaaatata tttaaggcaa aaatgttgac aaaaatatga aatctgcata taataaaaac
     5641 aaaggaacat atgagcagct gttcatatgt aaaaatgaat ggaggaagct gatatgggag
     5701 aaaataaatt agaaagctgt aattgtacta taattcataa ggatgtagtt gaaagagtga
     5761 aggaaaactt accagaagaa gaaattttat atgatttggc agaccttttt aaagctttta
     5821 gtgattctac aagaattaag attttacatg cactatttca agaagaatta tgtgtttgtg
     5881 atttagcagc tttactagaa atgactcaat ctgctatttc acatcaacta agagttttaa
     5941 aatcaaataa gcttgtaaag tttagaagag atgggaaagt aatatattat tctttagcag
     6001 atgatcatat taagcatatc ttccatgaag gctttaagca tatattagaa taaggaagtg
     6061 gtgagaaaat gagtaacaaa gatataaaat tagtattatc aggattaaca tgtgctaact
     6121 gtgctaataa aatagagaca agagttaata atttagatgg agtaaaggaa gctaatttaa
     6181 actttacaac ttctacctta gttattgaag gagatggaag taaggaagag gatgaattaa
     6241 tagttaaggc aaaagagata ataaataagc ttgagccaga agttaaggtt tataataaag
     6301 atgaagttaa ggaaccaatt agaaatactt cttcttgtgc tgatggaaga tgtgctatag
     6361 atgatggttc acatgataaa gatagtcata atcatcattc tcatggtgac tctcatgaac
     6421 attctcatga agatggacat gatcactcac atggtcacga tcattctcat aatgaaccta
     6481 ttactttaaa agaaaatata cctttaatat taggggtaat tatatatgca attgcagtag
     6541 tatttagaaa tgaatcttta ttaaatggag tattatttgt agtaagttac cttttaattg
     6601 gtggaaaagt attaactaca gcaattaaaa atatctttag aggagaaatc tttgatgaaa
     6661 acttcttaat gacagtagct actttaggag cattctttgt tggagaatat ccagaagctg
     6721 tagcagttat gttattctat gaagttggtg agctgttcca atcatatgca gttaatagat
     6781 caaggaaatc tataacttca cttatggata taagagctga ctatgcaaat gttataagaa
     6841 atggtgtaga agaaaaagta aatccagaaa cagttaatat agatgaagaa attattgtaa
     6901 gaccaggaga aagagttcct ttagatggta ttgtaataga tggaacaagc tttgtagata
     6961 cttcagcttt aactggtgaa tcagttccta gagaaatatc tataaatgaa gaaattttag
     7021 ctggatgtat taatactaat ggagttttaa aagttaaggt aagcaaaaac tttaaggaat
     7081 caacagtttc tagaatttta gaattagttg aaaatgcttc aaataaaaaa gctccaactg
     7141 aaaaattcat tacaaggttt gcaagagtat atactccaat agttgtattc ttagctttag
     7201 cacttgcaat aatacctcct ttagtgatta aggatgcaac atttaacgaa tggatatata
     7261 gagcatcaat attcttaatt gtatcttgtc catgtgcctt agtagtatct attcctcttg
     7321 gcttatttgc aggtataggt ggggcatcta gaagaggaat attagttaaa ggtggaaact
     7381 atttagaagc tttaaaaaat gtagattcag tagtatttga taaaacaggt actttaacta
     7441 agggtgtatt taaagtaaca gaaataaaca atgttaatat agaaaaagga gaattattaa
     7501 aggttgcagc aattgcagaa agtaattcaa atcatccaat cgctcaatca ataataaaag
     7561 aatatggtaa ggatgtaact tcttcagaaa ttaaagatta tgaagaaatt agtggacatg
     7621 gaattaagac tacaatagat ggattggaag tattaatagg taactacaag ttaatggaga
     7681 aattcaatat agcttataat aaggtagatt caataggtac tatagttcat gtagctataa
     7741 gcaaagaata taagggtaat atagtaatat ctgatgaaat taaagaaaca tcaaaggaag
     7801 ctattagtgg attaagagaa attggtgtta gacaatcagt aatgttaaca ggagataata
     7861 aggttgttgc agataaagtt tctgacatta ttggcttaga taaagtttat tcagaattat
     7921 taccaggaga taaggtagaa aaattagaag aaataattaa taataataaa tcagaaggaa
     7981 aagttatatt cgttggtgat ggtataaatg atgccccagt tctagcaaga gcagatatag
     8041 gtgttgctat gggtggtata ggctcagatg cagctattga agcagcagac gtagttttaa
     8101 tgaaagatga tccaaaggct ttagtagatg caataaaagt agcaagaaaa actaataaag
     8161 tattatggca aaatattaca ttagcattag tagttaaggt gttagtatta ggattaggtg
     8221 ccttaggaat ggctaatatg tgggaagcag taattgctga cgtaggagta actgtactag
     8281 cagtaataaa ctctacaaga tgtcttaaat aaaaaaacaa aaaaataaga agcttattga
     8341 caaatttcga tatttttcat ataattactt gagttgagaa caatcaggca atagggagca
     8401 tgctagattt tactttaatt acaagttagc ttgtactagt taagacttat gtataacgga
     8461 tctgctacgt tatacataag tctatttttt atttaattta tgcatcaata aatagtgtag
     8521 attttaatgt gaatataacg gcaaagataa attgacggct cgtaagacaa atgactgcaa
     8581 aaataagttc taaggctcgt aaaactacta agccaagagt tttggtaaaa ctcgcatacg
     8641 ctcagacaaa ccaacaactc taaggcttag tagtttttac ttcaccaaga acttctaatt
     8701 tttcgccata tgcttacttc accgtcaatt tatctttgct agtaattcag catttaaaat
     8761 attttaggct attacactaa tttttattga aattcagctt gcctgaattt cttccttcag
     8821 taggctttca tccacaaatt taaaaactcc tgctcaattt attactattt tataaatgat
     8881 attgtttatt gattagaatt attttaaaat agtaatatga gtatttaaat tagaagaaat
     8941 acagctttgt atataatagt ttgctagaaa tataatattt tcataaaaga aaaaacagaa
     9001 gtttgctaaa aatttaactt ttttatttga attttataaa aactttgtta aatagataac
     9061 ttggagtgtt ttaaaattgc atgaaaagtg gtaaactata ttataaaata gattaatttt
     9121 aatttaatat aatacaacaa gaaaattagg agaaaaatta ttatggataa gaaaaagaat
     9181 atttcaatgg ccgtaattaa gagattacct aaataccata gatatttaca agaattatta
     9241 aaaaatgatg tagatagaat ttcctcaaag gaattagggg aaaagatagg atttacggcg
     9301 tcacaaataa gacaagattt aaattgcttt ggagattttg gacaacaagg gtacggatat
     9361 aatgttaagg atctttataa tcaaattagc ttaatattag ggttaaacaa agagtataag
     9421 ggaattataa taggtgctgg taatataggg caagcaattg ctaattacag cagattttct
     9481 caagtaggtc ttaatatagg agcaatattt gatgcaaacc caaaacttat aggaatgaga
     9541 attagggata ttgaaatcga agatattgac ttattaaaaa attacttaag agaaaatata
     9601 gttgatattg gtataatctg tgtacctaga atcaatgctc aaaaggtatg tgatgtctta
     9661 gttgaaaatg gagttacagg aatatggaac tttgctcctg ttgacttatc agtgccagaa
     9721 aatgttacag tggaaaacgt acatttatca gagagtttat taacacttat atacttacta
     9781 catgataaag atgaaagtaa cttgtaaatt tatacatggg tttatttaga aatagttatt
     9841 gcaaaagaaa atttaagagt ttataataat aattgaagct tagcttcaat tattttttaa
     9901 ttttaattgt tacaatatta acaattgaaa ttaatttata ttcaaataat gttatttaaa
     9961 aaaattatat aattatgggt aaaaagggag gaactttaaa atggaattaa aaaatataat
    10021 tcttgaaaaa agtgaacact tagctattgt tactattaat agacctaagg cattaaatgc
    10081 attaaactca gagacattaa aagacttaga cgtagtgtta gatgatttag aaaaggataa
    10141 caatatatac tgtgttatat taactggttc tggagaaaaa gcttttgtag ctggagctga
    10201 tatatctgaa atgaaagact tatcggaaga agaaggaaga aactttggtc ttttaggaaa
    10261 taaagttttc agaagattag aaaaactaga caagcctgta atagctgcta tatctggatt
    10321 tgccctaggt ggtggttgtg agcttgcaat ggcttgtgat attagaatag cttctgaaaa
    10381 ggctaagttc gctcaaccag aagcaggtct tggaattaca ccaggctttg gtggaactca
    10441 aagattacct agattagtag gtgaaggtaa ggcgaaagaa cttatttaca cttgtgctac
    10501 tattaaggct gatgaagcat taagtattgg attagtaaat aaggtagttc ctttagaatc
    10561 attaatggat gaagcaaagg ctatggcaag tttaattatg gctaatgctc caatagcagt
    10621 taaactatgt aaggatgcaa taaatagggg aatgcaggtt gacatagata aggctgttga
    10681 aatagaagca ggagactttg gtaaatgttt tgcaacagaa gaccaaaaag aaggtatgac
    10741 tgcttttatg gaaagaagag ctaaaaattt ttcaaataaa tagtcagaaa aaatgaaata
    10801 tacaaaataa ttataatatt ataaagttta attatttcaa tttaagttgc aatatcaagg
    10861 aggtataatt aatgaatttc caattaacta gagaacaaga attagtaaag caaatggtta
    10921 gagaattcgc tttaaatgaa gttaaaccaa tagctgctga aattgatgaa acagaaagat
    10981 tccctatgga aaacgttgaa aagatggcta aactagggat gctaggaatt ccattttcaa
    11041 aagaatatgg tggagctggt ggagataccc tttcttatat aatggcagtt gaagagttat
    11101 ctaaagtatg tggaactaca ggagttatag tttcagctca tacttcacta tgtgcttctt
    11161 taatagatca atttggtact aaagatcaaa aggaaaagta tttaacagat ttagctactg
    11221 gtaaaaaact tggtgctttt ggattaactg aaccaggtgc tggtacagat gcagcaggac
    11281 aacaaactgt agcagttaaa gatggggaca attatatatt aaatggttca aagatattta
    11341 tcactaatgg gggagtagct gaaacattta ttatatttgc aatgactgat aaatctaagg
    11401 gaactagagg tatttcagca tttatagttg aaaaagactt tgaaggtttc tcaattggta
    11461 agaaagaaga aaagcttgga attagagcat cttcaactac tgagttagta atgagtaact
    11521 gcatcgttcc taaggaaaat ttaattggac aagaaggtaa gggatttgga atagctatga
    11581 aaactcttga tggaggaaga ataggtattg cagctcaagc attaggtatt gctgaaggtg
    11641 cttttgaaga agcagttaat tatatgaagg aaagaaaaca atttggaaga ccattatctg
    11701 cattccaagg attacaatgg atgatcgcag atatggatgt gaaaattgaa gcagctaaac
    11761 acttagtata taaagcagca tggcttaaag ataataagct tccatatagc gtagaagcag
    11821 caagagctaa gctttatgca gcagaagtag ctatggatgt aactacaaaa gctgttcaaa
    11881 tctttggtgg atatggatac actaaagaat atccagttga aagaatgatg agagatgcta
    11941 agataactga aatatatgaa ggaacatctg aagttcaaaa gatggttatt tcaggaagcg
    12001 ctttaagata aggggaggat ttataaatga atatagtagt ttgtttaaaa caagttccag
    12061 atacaacagc tgttaaaatt gatccaaaaa caggaacact tataagagat ggagttccat
    12121 caataataaa tccagaagat aagcatgcat tagaagctgc tttaacaata aaggataata
    12181 atggaggaaa ggttactgta ttaagcatgg ggcctcctca agctaaaaat gctttaagag
    12241 aagctttatg tatgggagct gatgaagcta tccttattac agatagagct tttgcaggag
    12301 ctgatacttt agcaacatct aaagcattag caggagcatt aaagaaatta gaatatgata
    12361 tagtattcgc tggaagacaa gctatcgatg gagatacagc tcaagttgga cctgaaatag
    12421 ctgaacactt agatatacct caagtaactt acgttcaaga tgtaaaggta gaagaagatg
    12481 gtttattagt aaatagagct ttagaagatg gatatgaatt aattaaagtt aaagctccag
    12541 ttcttttaac agcaattaaa gaattaaatg aaccaagata tatgaatgtt caatatatat
    12601 ttgacacagc taacaaagaa attcaaatct ggtcagcaga tgatatagat gtaaataaag
    12661 aagaacttgg acttaaaggc tctccaacta aggttaagaa aactatgact aaggaaacta
    12721 agggagctgg agaaataata aatgaagttc cacaagaagc tgcaaaatat gtattagcaa
    12781 aattaaaaga aaaacactac atctaagatt tgggaggtaa atgaagatga gtatagcaga
    12841 ttacaaaggc gtttgggtat ttgctgagca aagagaagga gaacttcaaa aagtttctct
    12901 agaactactt ggtgaaggta agaagattgc agataaatta ggggttaaat taacagcact
    12961 tttaatagga gataatgtaa aaggattagc agatacatta ggaagacatg gtgctgatga
    13021 agtattagta gcggaaaata aagggttaaa acattataca actgatggtt atacaaaggt
    13081 tatttgtgat ttagcaaatg agagaaagcc aggaatatta tttattggag caacatttat
    13141 aggaagagat ttaggtccaa gagttgcagc tagattatct acaggattaa cagctgactg
    13201 tacagtatta gatgttgatg ttgaaaaggc agatttactt gcaacaagac ctgcatttgg
    13261 tggtaactta atggcaacaa tcgcttgtcc agatcacaga ccacaaatgg caacagtaag
    13321 accaggagtt ttctcaaagc ttgctgatga agatagaaag ttcactgttg aagaagtagc
    13381 agttgaatta aaggattcag atataagaac taaaatagtt gaaatagtaa aagaaactaa
    13441 agaaatcgta gatataagtg aagctaattt catcgttgct ggtggtagag gagttggagc
    13501 taaagaaaac tttgctatct tagaagaatt agcagaagct ttaggtggaa ctgtagcagg
    13561 atcaagagct gctgttgaaa atggttggat agaaagagac tatcaagtag gccaaacagg
    13621 taagacagta agacctaaca tttatatagc ttgtggtatt tcaggagcta ttcaacacgt
    13681 tgcgggtatg caagattcag atcttataat agcaattaat aaggatgctt cagcgccaat
    13741 tatgcaaaca gctgattatg ctgtagttgg agacttatta aaagtagtac cagaaatgac
    13801 tgctcaatta aaagcaatga aagagaatga ataagtagaa gctaaaaaat gaaataatga
    13861 aaaattgatg attaaaatca aaagagttta ctaatttgaa atttatgata tggatgatga
    13921 aagaatgaat ttcacataat atggaatttg tgatataatt gaaatgtatt ttaaaaattc
    13981 tcataaaata aggattaaat aatttaatag ataatgtatt atggataatt gaggaaataa
    14041 atcagcagag ctgagttatg aaatagataa tttagccttt gtctaaatta ttaccttaat
    14101 tgttaattga taaatgttaa ctgttaatta aaagaaaggg tgtttaaaat ggaaaagatt
    14161 tttgttatag gtgctggaac tatgggtgct ggtatagttc aagcttttgc tcaaaaagga
    14221 tatgaggtta tagttaggga cataaaggat gaattcgtcg aaagaggaat taacggaatc
    14281 aataaaggat taactaagct cgtagctaaa ggaaaaatca ctgaagaaga taaggaagca
    14341 attcttggaa gaatatctgg aactacagag ttagctcttg ctgaagattg tgacttagtt
    14401 attgaagctg ctgtagaaaa tatggaaatc aagaaaagca tatttgctga attagatgga
    14461 atctgtaaag aatctactat tttagcttct aatacatcat ctttatctat cactgaagtt
    14521 gcttcagcaa caaagagacc agataaggtt ataggaatgc acttctttaa cccagctcca
    14581 gtaatgaagc tagttgaagt tataagagga atagctacat ctcaagaaac ttttgatgct
    14641 gtaaaagaat tatcagtagc aattggaaaa gagccagtag aagttgcaga agctcctgga
    14701 tttgtagtta acagaatact tattcctatg ataaatgaag caagtttcat acttcaagaa
    14761 ggaattgctt cagtagaaga tatagatact tcaatgaaat atggtgcaaa ccatccaatg
    14821 ggaccattag cattaggaga tcttatagga ttagatgtat gcttagctat tatggatgtt
    14881 ttatataacg aaactgggga tagcaagtat agagcaagca gtcttttaag aaaatacgtt
    14941 agagctggat atctaggtag aaagactgga agaggttttt acacttacta aaattaagat
    15001 atatattacc gaaaaaatcc cttgcttcct tatgagcaag ggatttttca attaacaatt
    15061 aacaatgggc aattaacaag taaggagaaa actcagctga gctgagattt ttaattaaaa
    15121 atgaagaaat taaagactta acgaatcaaa gaatgaagtg aaagatttga caagcttatt
    15181 aaggaaaact cagtggtatc tgagtttttt ttaattaaga atggagaaga ttaagagtga
    15241 aagaatgaag aaatgaagaa attagggggg aaagtgaggg gaggataatg aaacttggac
    15301 aatataaatt ttcaataaat aggagaatag gttgatttta atgggataac tatgaaataa
    15361 gaaaaagaat aataataact taggaaaaac atatagataa gctaagctgt taaatctaag
    15421 tgatttggaa caaatcacat caaaaactgc taattgttaa ctattaattg ttaattgtct
    15481 gagtccttgt ggtataatta aggaatagtt tgtttatttt aaggggataa ataaaataac
    15541 aagaggtgaa ataatgaatt ttgataaagt tagttttgaa gataataaag taattttaga
    15601 aggtctaaag aactttgata ttaagcaaat attagagtgc ggacaatgct ttagatggga
    15661 taagattagt gatacaaatt atataattgt agcttatgga agagtaatag aagtacttca
    15721 agagggggat aaggctacta tatataactc aaatgaagaa gattttaata atatatggat
    15781 aaattatttt gatttagaga gagattatga tgaaattaag actgaattag ctaaggatga
    15841 aatcttacaa aaaagtgtag attttggata tggaattagg attttaaatc aagatccttt
    15901 tgaaatgcta attagcttta taatatcagc tagaaatagt attccatcaa ttaagaagac
    15961 tgttaaaaag atatgtgaag catggggaga aagaatagaa tataaaggcg tggaatatta
    16021 cacatttcca acagcaaaag ctattaaaga agctacttta gaagatatcc aaggaacagg
    16081 agcatctttt agaagtaaat acatagtaga tactataaag aaggttaatg aagctataga
    16141 agttaaggaa gatatggaga ataatccaga taaatatagt gaaagacctg aaattttaga
    16201 tttcgattta gagtatatta agtctttaaa tgatgatgaa tgtcacgtag ctcttcaaaa
    16261 atttatggga gtaggagcta aggttgctga ttgtataatg ttattttcaa tggcaaagca
    16321 ctcagcattc ccagtagatg tatggataaa aagggcaatg atatatttct atgtagcacc
    16381 tgatgtatca ttaaataaga tgagagtctt tgctagggat aaatttggag catattctgg
    16441 aatggctcag caatatcttt tctactatgc tagggaaaat aagatagaag tttagattat
    16501 ttatcagcag aaaatagttg atatagtatt taaactggta agcatgtatt agtacaatta
    16561 caataaatga taaatgaata agaagtaata atataataat tagtaggcta ctgtatagta
    16621 ttagatacag tagcctattt ttattatgaa agaattagcg aaaattagta tatagacaaa
    16681 ataaatgata ataaaaagtt gttgacaaaa tatggaaata aaaattataa tgaagttaag
    16741 tggtaattac cattaagtgg tagatatcgt tatagttatt atttataggg gggattatat
    16801 ataaatttta ttataaacaa ctgataagaa tcgttgaata atcaagataa tgctatgtaa
    16861 gtaatataat tttaagttat atcaaaatta gaaagttaaa tcaacagtat aaagatttta
    16921 aattatatct aagacttgtc attaccaatt ttaaaatgat aggtaatata gcagttagta
    16981 atagtaaaat tcatattata aaattccaaa ttaaaagcat cataaaattc gtgtgaaaag
    17041 cccataggta tagaatcatg ctaatagtat ataacttatc ttaagttata gcatagttaa
    17101 gagaatgaga ataatatgtt aagcacacag cttaataaat tttagaaaat caatgggagg
    17161 aattatgaag agaaaaatga tagctgcaaa attaactgca cttgctttaa ctactgtttt
    17221 tgcatcaggt ctaatgattc aatcagtatc ggcttatgaa atttctgtag gaactaattt
    17281 agctacagaa aacataattt cagaacaaaa agcaaacgac tacaaagtca ttggtggagt
    17341 taaggatgtt atacaatcag agaataaagt cacttttgaa atgactactg gtgagaagat
    17401 aagagtatca attttggaaa atgatgtact tagaatatat atggatccta aaggggagtt
    17461 tcaagaagat ccaactccaa actcaaagga tcatatagct aaaattattg ataaacaaga
    17521 aagtgaatat agcaatgtta cgccagtatt agaaatgggt aatactataa aggtttccac
    17581 agaagttatt gagttaagag ttgataaagc aactggaaaa atggaattat tcaataagaa
    17641 aacaaatagc ttagtatgga aagaagcaga accattaaag tataaggata ctgagactat
    17701 ccaaacttta gaagcttctg aagatgaata tttctatggt ggtggacaac aaaacggacg
    17761 attctctcat aagggaaaag ttataaatat taaaaatgaa aataattggg ttgatggagg
    17821 agtttcaagt cctacaccat tttatttttc tactaagggt tatggggtaa tgcgtcatac
    17881 ctttaaacca ggacaatatg attttgaagc gactgaagaa ggaaagatga ctgcgaagca
    17941 tgatgaaaaa cgtttcgatg catattattt tatagatgaa aagccaacag atattattaa
    18001 taagtttact gagcttactg gtaagccaat attattacca gaatatgcat tttatctagg
    18061 acatgcaaat gcctatgctc gtgactggat taatgatgaa acaggtcaag aatctcaaac
    18121 tccaaagcca ggatttgatc gtcaagaaac attaatggta gatgctaaaa aagttgttga
    18181 tgagcatatt gataatgata tgccacttgg atggttttta cctaatgatg gatatggtgc
    18241 aggatatggt cgtgcagata caattgatgg taatatagca ctattaaaag agtttgttga
    18301 ctatacaaaa agtaaaggta ttcaaactgg actttggaca caaagtgact taaagccaac
    18361 aggggttgga gaagtttact tgcaacgtga tatagataaa gaagttggtg aagctggaac
    18421 aaatgcagtt aagacagatg ttgcatgggt aggagcagga tactcttttg cacttaatgc
    18481 tgtaagacaa gctgcagagg gcattgtaaa taattcagta gatagagcta gacctttcat
    18541 tgtatcttta gatggatggg ctggaactca acgttatgct agtatttggt caggagatca
    18601 atatggtggt aattgggagt atattcgttt ccatatacca acatatatag gatctggatt
    18661 atcaggacag cctaatgtag gttcagatgt agatggaata tttggtggaa ataaattaat
    18721 tcaaactagg gatattcaat ggaaagcatt tactccagtt gaaatagata tggatggttg
    18781 gggaagtaac cctaaaaagc catatatatt tggtgaacca tataactcaa ttaaccgtat
    18841 gtatttaaag ttaaaggcag aaatgatgcc atataactat agtattgcca atgaagctac
    18901 taatgacgga gtacctatgg tgcgtgcaat gatgttagag taccctgaag catatactta
    18961 tggaacaaac actgaatatc aatatatgtg gggaccgaac ttattagtag cacctatata
    19021 tcaagatact gcttcagatt cagcaggaaa tgatatacgt aatgatatat atcttccaga
    19081 tgaagatcaa atatggattg attactttac aggacaacaa tacagaggtg gtggagtatt
    19141 aaataacttt gatgcaccta tgtggaagct tcctttattc gttaagaatg gggctataat
    19201 tcctatggct aatgagaaca atactccaga agatatagat gattcacaaa gaaagtttga
    19261 agtatatcca agtggagata ctagttttga aatgtatgaa gatgatggat taacaacaga
    19321 ctattatgaa ggaaagtcag caacaacaat gataacttca tcagctccta agactggaaa
    19381 gggaaaagct gttattaaag ctggattatt aacaggaagt tatgaaggga ttgttacaga
    19441 aagatcaact gaattcacag taaatgtaag tgaaaaacca acagatttat cattaaaagt
    19501 tggaaatgaa aatgttgact taaaagaagc agcttcttta gaagaatttg aaaaaggaac
    19561 aaacttatat ttctatgatg aaagtccaaa tcttaataaa tattctacag aaggttcaga
    19621 atttgcagat gtggatataa ctacaactcc taagatttat gtaaaggtag acaaaacaga
    19681 tgtgacagtt aatgaagttg agttaactat taatgatttt ataaatactc aagatatttc
    19741 taaaaatgaa gtaaacaaag atttaaaagc tcctaagaac tttgaggctc cagaggattt
    19801 aataacttca agttcaatag atttaacttg ggacaaagta aaagatgcag aatcttatga
    19861 aattgaaata gatggaataa tacaaagaaa tattacatca acagaatata gtcataaagg
    19921 cctagatttt gatactgagt atagctatcg tattcgtagt gtaaataagg atggttattc
    19981 agagtggagt aaagaattaa ctgctagaac agacttagat ccatatagaa atgttcctaa
    20041 agacatgact gttaagtgga cagaaggtca atatagtagt gatgtaccag caaatgctgt
    20101 agatggagat gataactctc aattccactc aaagggaaat gcaattgatg taccatttat
    20161 aattgacatg aaaaaagctt atcaaattga aaaattagag ctactgttta gaaatgcagg
    20221 aaatggttct gtaaagcgtg ctgaaatata tagcagctta gatggtgtta attatcaaaa
    20281 ggtatttagt aatgcaagcg attctggaaa tgcagcttgg actactgatg gacaagtaaa
    20341 aactatagga tttgatgctc caattaaagc gcgttacttt aagattgtaa ctaaagaatc
    20401 agttggtaac ttcttgacta tgagagagtt tagaccatac atggtagatg gaagtaaggg
    20461 tcaacttgtt ggtgactgga acaatggtgg aacaattgaa gaaggagatt taacattcct
    20521 tcaaaattac actggattat catctgtaga tgcagattgg gattatgtat caatggctga
    20581 cttaaacttt aataatgtta ttgatgctta cgatataagt tatgtagcaa gccaattaga
    20641 aggtggtata gtaccaacag aaggtggaaa tgttgctgga gaaattatgc tagttccgaa
    20701 taaagcaagt atttcagcag gcgaaacatt tactgttgat gttgtaggta ctggattatc
    20761 agatgttaat gcctttagtg ctgagattcc tttagattca agtaagtatg aatttgtaaa
    20821 aacagaaggt gcagtctcaa cagcttctat gaagaacttc tcaaagatta gacttcatag
    20881 tgataattca caagatcttt atactgtatt cactaatatt ggtgataacg ttagacttaa
    20941 cggaacagat actcttgcaa caattacttt aaaagctaag agtgatatta attttgactt
    21001 agcattaagt gatgcattag tagttgatag taacttaaat tctaaaaatg cagttgctaa
    21061 tattactaat ccagaagatc cattaccagg agataaagat tcagtagtga agattggaaa
    21121 agaaagtatt actgtaactg gtgatgagtc acaattacaa acaggaatgg gattaagcag
    21181 attaatagat ggaactacaa gtagtgatga tagttctcgt atggatttaa aatgggtata
    21241 ttctgctgat caagcagata agggaaagct tccatttgaa atgacattta catttaagga
    21301 agctaagaag tttaataact ttacaatata caatagaact aatgctgatg gtaaaaataa
    21361 tattgcagca atgaaaaaag taaaagcagt tggatactta aatggtgttg caacagattt
    21421 aggtgaagta tctaatatta caactgcaaa gactatattc aatttagaag gtaaatcatt
    21481 tgataagatt gtaattacag ctttagaatc taataaggat atgtacactt tagcaataaa
    21541 tgaaatagaa ttctatgaag aaaagcaaca agcaccatca tcaatagaat ttttagaaaa
    21601 tgcaccaact aatctttatg ttaataagat agcacctata tttgcaaaag tattacctga
    21661 aactgcaaat ttaaattata aacttacttc agataatgaa gaggtagtaa aggttatacg
    21721 tgtagataat ggtaattcat ctacttatta tttaagaggg gttaagccgg gtacagcaaa
    21781 ggtaacagct acaacagttg atggaaaact tagcgatcta catgaagtta cagtacttga
    21841 tggatttgat aaatctatat taattgaagc tattgaaaag ggtaaatcat actcaaagaa
    21901 tagtgaaatt tatacagagg aaacttattc agaattacta aaggctatag aaaatgctga
    21961 aaaggtatta gaatcagcaa agacagaatc agaattaagt tctgccatta tatcaataag
    22021 ggtagctata aacggattaa aagaacgtga agaacctaat ttaaatgtaa ttgactttaa
    22081 taaattagaa gctatatttg ctacaactga agcagatagt gactttatgg aaaatgctgt
    22141 agatggtgat gaaaatacaa tatggcattc aggttatcaa agtaaagata agctaccagt
    22201 ttcaatagta gttaagctag ataagcctta taaccttaat caagttgatt atttaccaag
    22261 acaaaatagt agaaatggac atgtaactga atatattgtt gaaactagtt tagataatga
    22321 aaattggaca gaagctagaa gaggaacctt taaagaagca agtaatggtt caggacttga
    22381 aaataaagga tataatccaa tacgcttcaa tactactaaa gctcaatatg ttagatttac
    22441 tgcattaaaa actttaggcg atactcgtga taaatatgca agtgctgctg aacttaaatt
    22501 ctatggacaa tcagaagtag ataaatcaaa cttaagtgct aagattagtg aagcagaagc
    22561 attagttgaa gctgattaca cagcagaaag ctttgaagca gttaaggtag caattgatgg
    22621 cgctaaggta atattaaatg ataatttagc aactcaagaa caagttgatg aggcaattag
    22681 tattttaaca gatgcaattg ataatcttgt taagaaagat gatgttgaag aagttaataa
    22741 aacagtttta gcaatggcta tagaatatgt tcaaaactta aaggcaaatg gagaacttga
    22801 agatgttgtt ccagcagtaa ttaaagaact tgaagctgca ttagaagaag ctaaagaagt
    22861 tttagctaat gaaaatgcta cacaagctca agtagatgta gctgaaaaga gattaataaa
    22921 cgtaattcat atgctagagt tcaaaaaagg agataagaca aagcttaaag aacttgttga
    22981 aataattaaa gttttagatg aaagtaaata tacaacttca acttggaatg cattgcaagt
    23041 agagcttgaa aaagctgaca aagtaattgc agatgaaaat gcaatggaaa aagaagttgc
    23101 taaaacttat gaaagcttaa ataaggcatt cgctgaatta gaattagtag ctgataattc
    23161 taaacttgca caattagtag ctgaattaga aggtaaagat ttatctaagt atacaacagg
    23221 aactgttaat aagttcaagg cagaattaga atatgctaag ggaatcttaa gcaataagga
    23281 tgcaagtcaa gaagaaataa atgaagctta taataagtta ataaaagctt accttgattt
    23341 aagattaatc ccagataaat ctcttcttga agatttaata agcaaggctg aatcaataga
    23401 tttatctaaa tatactaagg aaagtgctaa taagctaagt ttagcattag ctaatagtag
    23461 atcaatctta aacaaagaag aggttactca aaatgaaata gatgaatcag cagatgaatt
    23521 gaaatcagct ttagaaggac taatagcaag taacggaaat ggcaacggta ataacaatgg
    23581 aaacaacggc ggcggaaatg gaaataataa cggaaataac ggaagtggaa atggaagcaa
    23641 caacggaaac aacggaagtg ataatggaaa cggcaacggc aacggtagtg gaaacaacaa
    23701 tagtaatggc aacggaaata acaacagcaa taatgggggc aagttaccaa gtactggagg
    23761 aacaccagca ggtgctatag cattatttgg agtattaact tcagcattag gagtttctat
    23821 atttaaaaag aaaaagtaaa taagtaaaac tataatttag tctgcaagga tttaatagga
    23881 cggatcaagt aagggaatag agccggtttc atcattaaat ctaagtaggc tattttttgt
    23941 gaaaaagtat aaatactatt ttaattagct tctaataata aataataata ttaatatcat
    24001 agaataagat tatagtattt aatagaaata gattaatata agcttcaaga atcacagatt
    24061 ttaataagta taagaggatt aataagtatc tgataaattt atataatgtt caatgcttac
    24121 tggaaattgc attagctaac ataaatattc taacgtgaca aatttatata atattaaata
    24181 attacctatg aatatatttc tactaagata gttagaataa aatataagtt tagtagtaaa
    24241 taaataaaaa aatagagaaa tttcagaaaa attcgatttt agcaatatat tatattggaa
    24301 aagttaatca atgattatat aattatattg tggattttta tatattgttt aatttttata
    24361 taaatgatta agtgaataat gtaacttaaa tatttttgct atgtaactta ctttatagcg
    24421 attttataaa aagtagaatt tttattacaa tgcatataca taaattatct acagtaatga
    24481 aaataataat ataaaatatc caataataaa aatttcaaga gtgtgtaggg ggaagaagaa
    24541 gtatgtttta tttaggaatt gacggtggtg gaactaaaac aagatattta ttagttgatg
    24601 aaaagcttaa caaagtagct gatgttgaag gttctactat tcatatccat caagtaggag
    24661 tggaagggat tcaaaagcaa ttaaatgaaa acattttaaa ggtttgtgag gaagctaaaa
    24721 tatcagtaaa agatatagcc tatactttta taggggtacc aggatatggt gaaagccttg
    24781 aagatatgaa taaaatagat gctgccataa aagaagttat ggtaacacct tactcaatag
    24841 ataatgactc agttaatggc tgggcaggtg gaactgcttg taagccggga gttaatatag
    24901 tagcaggtac tggaagtata gcttatggaa gaaatgcaga aggtaaactt gctagatgtg
    24961 gtggatttgg acctggaata ggtgatgatg g
//
