LOCUS       NC_014376.1            23252 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_014376.1 [Clostridium] saccharolyticum WM1, complete sequence.
ACCESSION   NC_014376
VERSION     NC_014376.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:47:57
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 398490
            Orig. end    :: 421742
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23252
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[408490:411742]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13252
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..23252
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23252
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Putrescine2spermidine"
                     /region_number="2"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             1684..1881
                     /locus_tag="ctg1_370"
                     /transl_table=11
                     /translation="MRAYWGYGLQEVRRFVTRTVLERPAIESESLVWESNSQRAGSKVP
                     RDTRNLVGIRGDHPPRLNTT"
     CDS             4582..5070
                     /locus_tag="ctg1_371"
                     /transl_table=11
                     /translation="MKREQNVIRILMVCLGNICRSPMAEFVMKDIIEKKHLSNRFFVAS
                     AATSTEEIGNPVHRGTREKLKEHGITTEGKYAVQLSRKDYDKYDYLIGMEQRNVTNMLK
                     ILGGDPEEKVRRLMDFSVAPRDIADPWYTGDFDRTYDDIYEGCQALLAYILKKESIKN"
     CDS             5091..6161
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_372"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 7.1e-13, bitscore:
                     47.4, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPLNFMVVGSGWRSLFYARIAKAYPDSFNLTAFLCRTEEKAVQI
                     QKETGIKAVTSPEECLSEKPDFIVVAVNKDSIFQVTGEWARKGYPVLCETPAAMKLEDL
                     QELWRIHTQEGARIQVAEQYFKYPVFSAAIEVVKRGYLGEPYMVNLSAVHDYHGASLIR
                     QFLGTGFENMKLYGKKFLYPVVETDSRYGLVEDGRISERERVRMTFEFEGGKTAFYDFN
                     GIQYHSRIRSRHLNVQGARGELDDWTLRYAGKDNRSREFQIIKEPFETGNGIKQITMGQ
                     ELLYRNPFIDLGKANGLPQDETAIGTLMLGMRRFIEEGVEVYPLAEGLQDAYVRILMEQ
                     ALKSGQTVESKTQVWG"
     CDS             complement(6231..7304)
                     /locus_tag="ctg1_373"
                     /transl_table=11
                     /translation="LIYLPIEKLTEGMELARNIPGINPMLPFAVTGCKLSERMINRMKT
                     IGIQGAYICTALTEGIEPEDFVEPELKAKMLTSIRDVFDQSLKKFTFQSSRQVYAEIAK
                     VAESVVMNVLNKDKYLFQMIDIRDYDGYTYSHSLYVGILSVLLGKYIGLSISNLNDLAL
                     CGLLHDIGKTDIPIDITNKPGPLTSGEFEIMKQHPSLSYKKLGEHLVISQAVLQGVQTH
                     HEKFDGTGYPFGLSGKDIPLYARILAIADVYDALNSTRPYRKAWSPRRIFDYLTSCSNT
                     HFDPELLTAFLNCVSAYPIGTIVHLSDGSSAVVKDNTPGFSLRPIIRFISPHQKAGRDV
                     DLSCESFNLTIIDDDDI"
     CDS             7715..7987
                     /locus_tag="ctg1_374"
                     /transl_table=11
                     /translation="LKEYIEERAVAIANYIIDYHATVRQTAKKFGISKSTVHKDVTDRL
                     EHINPSLAARARVILDINKSERHIRGGLATKEKYQHRLQMCSKKN"
     CDS             8522..9994
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_375"
                     /sec_met_domain="OKR_DC_1_C (E-value: 8e-11, bitscore:
                     40.3, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 6.9e-122,
                     bitscore: 404.9, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKDQMRAPIYEALETFQKKRVVPFDVPGHKRGRGNPELARLLG
                     ERCVGLDVNSMKPLDNLCHPVSVIREAERLTAEAFGAADAFLMVGGTTSAVQSMILSVC
                     KAGDKIILPRNVHRSALNALVLCGAVPIYVNPEVNSMLGISLGMEIGQVEKAIQENPDA
                     AAVFVNNPTYYGICSDIRSIVRVAHAHGMKVLADEAHGTHLYFGKGLPVSAMEAGADMA
                     AVSMHKSGGSLTQSSLLLLNKGVNGDYVRQIINLTQTTSASYLLLSSLDISRRNLALRG
                     EESFAKVVEMAEYARGEINSIGGYYAYGRDLINGTSIFDYDVTKLSVYTLGNGLAGIEV
                     YDLLRDEYDIQIEFGDICNLLAYISIGDRIQDIERLVGALADIERLYKKDRAGMLSGEY
                     IAPKVAVSPQKAFYSQKISVPVRESAGRISGEFVMCYPPGIPILAPGEMITEEIVEYII
                     YAREVGCSMQGTEDPAVERLMVLKEQIREGER"
     CDS             10001..10858
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_376"
                     /sec_met_domain="Spermine_synth (E-value: 1.5e-50,
                     bitscore: 169.2, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 8.3e-15,
                     bitscore: 52.4, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIWFSKFHTSNVKLSVRIDKQLFSGESEYQRIDVFESQEFGKFV
                     SLDGDIVFSEKDEFIYDEMVTHVPMAVHPNVRDVLIIGGGDGGVAKELLQYPLIRSIDV
                     VETDKLFVDVCRDIFPEVSCGLSDPRVKVYYDDGLRFLRNKKEAYDLIINDSTDPFGHT
                     EGLFTKEFYGSCYKALRSDGIMVYQHGSPFYDEDEAACRSMHRKVYRSFPISRVYQAHI
                     PTCPSGYWLFGFASKKYHPVNDFKPAAWNQLKIETWYYTTNLHTGAFMLPKYVEDLLEE
                     EEKE"
     CDS             10855..12123
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_377"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 1.1e-42, bitscore:
                     144.9, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 1.2e-30,
                     bitscore: 104.4, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRLLVIGCGGVASVAIHKCCQNSEVFTDICIASRTKEKCDALKD
                     KLAGTTKTRIETAKVDADHVDEVIALIKDYKPDAVLNVALPYQDLTIMDACLATGVDYI
                     DTANFEPENTDDPEWKAIYEKRCKELGFTALFDYSWQWDYKERFEKANITALLGTGFDP
                     GVTSVFSAYALKHYFDEIHTIDILDCNGGDHGYPFATNFNPEINLREVSSNGSYWEEGR
                     WIETEPMEIKSRYHFPQVGEKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSYLTHMK
                     CLENVGMLSTSPVMFNGQEIVPIQFLKALLPDPASLGPRTKGKTNIGCIFTGVKDGKEK
                     TIYIYNVCDHEECYKEVESQAISYTTGVPAMIGAMMVVTGQWKNPGVFNVEEFDPDPYM
                     EALNKWGLPWVVCEDPETVTVWR"
     CDS             12131..13252
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_378"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 1e-12, bitscore:
                     46.1, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIEDLKTPCYVIDEGRLEKNLDILKKVKESTGCRILLAQKAFSC
                     FAEYPLIGRYLDGTTASGLYEARLGREEMGLETHVFAPAYKEEDFKELTEICDHIVFNS
                     FSQLEKYHNSLGGVKAGIRINPQCSTQEGHEIYDPCAPGSRLGVPLDHFKEEWLPWLSG
                     FHFHTLCEQNSDDLKKTLDAVEEKFGKYLSGLSWLNMGGGHHITREDYDIGLLETCIKR
                     IKEKYGLQVYLEPGEAVALNAGYLVTEVMDVVDNGIKTLILDASAACHMPDVLEMPYRP
                     PLKDSGKPGEKAFTYRLSSCTCLAGDVIGDYSFDRELKPGDKLYFMDMAIYSMVKNNTF
                     NGMPLPAIAIMDKEGDCHVIKRFGYEDFKNRLA"
     CDS             13282..14376
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAD_porph"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_379"
                     /sec_met_domain="PAD_porph (E-value: 2.8e-122, bitscore:
                     405.9, seeds: 436, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKLKSLPAKDGFYMPGEFEPHWGCIMIWPKRPGSWPFGAGKARK
                     AFARIAEAIADSEQVIMLAEEDVAENAREMLSGRIQIAVMESDDAWARDVGPTFVVNKD
                     RRVRGIDWQFNAWGGTFDGLYPDWKKDDLLAGRFCERFGYPVYDAGHFVLEGGSIHSDG
                     EGTLLVTESCLLSPGRNPSLTKLQIQEQLKCYLGAVKVIWLKAGIYQDETNEHVDNVCA
                     FVRPGEVVLAWTDDQHDPQYEMSLADLRILEKETDAAGRHFKIHKLPIPKKPVCITEEE
                     LTGLSFEPGEDEREAGERLAASYVNFYISNGGVVVPQFGDDHDSEAVRILGECFPERKI
                     YPVYARDIIVGGGNIHCITQQIPL"
     CDS             14432..15313
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CN_hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_380"
                     /sec_met_domain="CN_hydrolase (E-value: 4.4e-53, bitscore:
                     178.2, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRMITAAAVQMKCCDDVKKNIEHGERLVRQAAEEGANVILLPELF
                     ERPYFCQERRYDFYDYAKPAEENQAVKHFAGIAAELQVVLPISFYEQSGNTMFNSVAVL
                     DGDGTNLGVYRKTHIPDDHYYQEKFYFTPGDTGFRVFDTRYGKIGIGICWDQWFPETAR
                     CLALQGAELILYPTAIGSEPILECDSMEHWRRCMQGHSASNIIPVLAANRVGVESVIPC
                     MENGNQCSSLKFYGSSFITDHTGALVASMDREEEGVICASFDLDQLAADRRNWGLFRDR
                     RPGMYGDISKKA"
     CDS             15380..15811
                     /locus_tag="ctg1_381"
                     /transl_table=11
                     /translation="MKRLLSRKWMIFFGLAMWVLVVRTLSGCTFNGDNGDKVRDMELTV
                     VADADIPQELRQIIAEKQQSPFKLTYSDDKNLYIVVGYGKQASGGYSIAVNELYLTDNS
                     IVLDTELIGPEKGENTGTEPSYPFIVIQTEMSELPVVFQ"
     CDS             15983..16696
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Hexapep"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_382"
                     /sec_met_domain="Hexapep (E-value: 5.4e-09, bitscore: 33.4,
                     seeds: 216, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILKDIWLDVSAVKERDPAARSKLEVLLLYQGVHALIWHRFAHWF
                     YQHRMFFIARFISQLARFFTLIEIHPGAQMGHGILIDHGCGVVIGETTVVGDNCTIYQG
                     VTLGGVGLNKGKRHPTLGNNVTVGAGAKILGSFEVGDNCTIAANAVLLKPLESNVTAVG
                     IPARAVKIDGVPLPKKESNLVTMDHYCKMEERVRDMEETLLKLQKELSSYREKEGAIQT
                     EASPEERSEEEGNRE"
     CDS             16817..18388
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_383"
                     /sec_met_domain="LysM (E-value: 9.8e-12, bitscore: 42.8,
                     seeds: 155, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLELVKKNIHMNRWKGYATSQITLDDDFIVPDSMDDVDQMILSSG
                     EITIDSVKNQTERVVVRGKLDFMILYRGAEGGLQTLSGSINFEEPINVPGLEERDIVQL
                     AWELEDLNAGIINSRKLSVKAIVTLTVKVETSCDVNAAVDVDTGSASSDVPMVETLRRN
                     LDVVSVALRHKDTFRIKDTTTLSGNKPNIDHILWTEMKLRSVATRPMDGKMMLDGELLV
                     FVIYQGEGEGAPIQWIEESIPFSGELDVPDMTEDMVPVVTVHLIHKDIEAKPDSDGEMR
                     EMDADAVLELDMKLYREENMELLNDLYSTNRELTLQTGEACFDKILTKNMSKCKIVEKI
                     SLDQADRILQICHSEGAVKIDDTEIKEDGLHVEGVIEVRILYMTSDDSQPIQSAVEDIP
                     FHYLIEAPGINDKTICQLNPGLEQLSAVMMGGGTIEVKSTISLDLLALQPVCQQIITNA
                     SEAPMDLNSLQKLPGIVGYIVQPEDSLWKIAKKFHTTIDTIIATNGLTDKSVKPGDRLI
                     LVKELS"
     CDS             18674..18919
                     /locus_tag="ctg1_384"
                     /transl_table=11
                     /translation="MNYTYILKCADDTLYCGWTNHLEKRLSAHNQGKGAKYTKARRPVV
                     LAYWEEFSTKEEAMRREAAIKKLSRRDKLKLMGEIG"
     CDS             complement(18969..19616)
                     /locus_tag="ctg1_385"
                     /transl_table=11
                     /translation="MEFKIKDPVSAITHFIAMILALVAATPLLIKASSDGRLHLAALTV
                     FCISMVFLYAASTIYHTLDISPKINRLLKKIDHMMIFILIAGTYTPVCLIVLGDETGWG
                     LLALVWGIAVTGILIKACFIMCPKWFSSSLYIAMGWVCVLAFTKIIDALSPAGFLWLLA
                     GGIIYTLGGIIYALKLPVFNAKHKSFGSHEIFHLFVMGGSLCHYILMYHFVA"
     CDS             19821..20558
                     /locus_tag="ctg1_386"
                     /transl_table=11
                     /translation="MNQTIKELMERKSVRVYEERVIEPEKKAAILEAALQAPTAGNMTL
                     YSIIDVTDQKRKETLSITCDNQPFIAKAPLVLVFVADYHRWYELFCHYEDVVRKPGLGD
                     LMLACDDALIAAQNAVVAAESLGIGSCYIGDIMEQYETHRDLFGLPKYAVPAAMVVFGY
                     PTKQQAERKKPERLRPEAVVFENSYRRLDPEEFTRELKRIQGREEDFEHWVKAFCKRKW
                     NSDFSTEMSRSMEAMIESWKKEE"
     CDS             20540..21268
                     /locus_tag="ctg1_387"
                     /transl_table=11
                     /translation="MEERGVKEAMELNILYEDEEILVAEKPVGMESQSARSFEPDMVSE
                     VKKHINRLSPKQGEPYVGVIHRLDKPVGGVMVYAKTKDAAESLSRQVSMHQMEKIYYAV
                     VCGKPVENFGAYVDYLWKDGKNNCSKIVDKGIKGAKLAELSYQIVDERSIGNEVCSLAK
                     IILKTGRHHQIRVQMAGHGTPLWGDQKYNPLFQKGYRSGNVALFAYSLTFTHPVTKKRM
                     TFSVKPKGDIFETFLLPEMA"
     CDS             21369..22472
                     /locus_tag="ctg1_388"
                     /transl_table=11
                     /translation="MVKPSRKLKKTLLILGVTGAVYFSFRYLLPLVIPFLIAYVFALSL
                     RPSALWIERKTRFAIKGREISVPLAMIGGIEIILFMIVFGIILYVGGRKIFMEARLLLQ
                     NLPVILGEIDRWLMDNCSFAERFLKLPDGYMVEVVRDIISGGQVAIKGRIMPFLMVNSM
                     TIMKWMVQATVILIILLIATVLSLQEMDEIRERRDNSIFCFEYAMLGRRLTTVGSAWLK
                     TQGAIMLFTMVVCSIGLFLLGNPYFILFGIGIGLLDALPIFGTGTVFIPWALFSMINKN
                     WKYGTGLILIYVICYFLREIMEAKIMGGKVGLTPLETLASMYVGLQLFGLLGFILGPIG
                     LLIVEDIVEVYEVSYCHDGKKGADPEE"
ORIGIN
        1 tcgaagcaac gcgaagaacc ttaccaagtc ttgacatcgg aatgaccggt ccgtaacggg
       61 gccttccctt cggggcattc cagacaggtg gtgcatggtt gtcgtcagct cgtgtcgtga
      121 gatgttgggt taagtcccgc aacgagcgca acccttatcc ttagtagcca gcagttcggc
      181 tgggcactct ggggagactg ccagggataa cctggaggaa ggtggggatg acgtcaaatc
      241 atcatgcccc ttatgatttg ggctacacac gtgctacaat ggcgtaaaca aagggaagca
      301 aaggagcgat ctggagcaaa ccccaaaaat aacgtctcag ttcggattgt agtctgcaac
      361 tcgactacat gaagctggaa tcgctagtaa tcgcggatca gaatgccgcg gtgaatacgt
      421 tcccgggtct tgtacacacc gcccgtcaca ccatgggagt tggtaacgcc cgaagtcagt
      481 gacccaaccg taaggaggga gctgccgaag gcgggactga taactggggt gaagtcgtaa
      541 caaggtagcc gtatcggaag gtgcggctgg atcacctcct ttctaaggaa gaagaagtaa
      601 gggttttaga tactgttgag tctttggttt tcaaaggaag taaaaagaat aaagaaacac
      661 caagagaacc gtaatgtgga acctcgcgaa taattcgctc ggtcgcggct gcgccgctta
      721 tacaatgaat caaaaaactg cttatgaaag caagctttca acacagtttt ccgcttaatt
      781 gtgcacgcat tactagtgag acacgaaatt tctggtgccg atgcgcttag gggagacacc
      841 cgttcccatc ccgaacacga tggttaagac ttaagcggcc gatggtacta tgctggagac
      901 ggcatgggag agcaggtggg tgccagatta cataaaaaaa atcactcgaa ggagtgtttt
      961 atatagaacg gacacgttcc aatgggcgga gggaaaagcg aagcctgtgt taaagaatgt
     1021 gttaacctga ttcagcaggg cagtgctgtt ttatatagct ggtttttacc agtgattcgt
     1081 gagtttgagt tgatcgagct ttcgaatgac tgataaactt cagtcatagc ggtacggtta
     1141 cgaaggagca cttcgaaaag cgaagacttc tgattgcatc gcgcatgtac cttgaaaacc
     1201 acatattgaa atatatctag attagttttt atatgttaaa gtataaaaac aaaatcaaga
     1261 catccgaggt gttacatcta acgatgtaac caaacaaaac tcgttaaaat aaccgtaacg
     1321 tacggtgaaa taacaaacct aagaccagag atacaacgct atgtatctta gattagtaac
     1381 ccgcacccgc aggtgaacat cgaattggtt aagctaataa gagcgcaggg tggatgcctt
     1441 ggcactaaga gccgatgaaa gacgtgataa gctgcgaaaa gcttcgggga ggagcaaata
     1501 tcctttgatc cggagatgtc tgaatgggga aacccagctg agcaaacctc agctgtcgta
     1561 tggtgaatcc atagccatac gtcgggaacc cggggaactg aaacatctaa gtacccggag
     1621 gaaaagaaag aaaactcgat ttccaaagta gcggcgagcg aaatggaagg agcctaaacc
     1681 agtatgcgtg catactgggg ttatggactg caagaagtga gacgatttgt taccagaacg
     1741 gtcctggaaa gaccggccat agaaagtgaa agccttgtat gggaaagcaa tagtcagcga
     1801 gcaggatcca aagtaccacg agacacgaga aaccttgtgg gaattcgggg ggaccacccc
     1861 ccaaggctaa atactactta gtgaccgata gcgcatagta ctgtgaagga aaggtgaaaa
     1921 ggaccccggg aggggagtga aagagaacct gaaaccctgt gtttacaagc tgtggaacca
     1981 cattttaagt ggaaccgcgt actttttgta gaacggtccg gcgagttacc gttactggca
     2041 aggttaagca ctgaaggtgc ggagccgaag ggaaaccaag tcttaatagg gcgaatgagt
     2101 cagtaaaggt agacccgaaa ccgggtgatc tacccatgtc caggttgaag tttccgtaaa
     2161 aggaaatgga ggaccgaacg cacatccgtt gaaaagggtg gcgatgaggt gtgggtaggg
     2221 gagaaattcc aatcgaaccc ggagatagct ggttctcctc gaaatagctt tagggctagc
     2281 ctcgtattag tctgccggag gtagagcact gaatttccta gggggcgtca aagcttacca
     2341 aagaatatca aactccgaat gccggtcaga tgatgtacgg gagtcagact gcacgagata
     2401 agttgggcag tcaaaaggga aagagcccag accaccagct aaggtcccaa agtgcgtgtt
     2461 aagtggaaaa ggatgtggga tttcagagac aactaggatg ttggcttaga agcagccaca
     2521 cattcaaaga gtgcgtaata gctcactagt cgagaggtcc tgcgccgaaa atgtccgggg
     2581 ctaaaacacg acaccgaagc tgtggaatgt atgtaaatac attggtagag gagcattctt
     2641 aacgcacaga agcattaccg taaggagatg tggagtgtta agaagagaga atgccggaat
     2701 gagtagcgag atggaggtga gaatcctcca ggccgaatat ctaaggtttc cagagtaaag
     2761 ctgatctgct ctgggtaagt cggggcctaa ggcgaggtcg aaagacgtag tcgatggaca
     2821 acaggttgaa attcctgtac cgcatatcat cagaactgtg gggacacaga accgaggaag
     2881 aacccgggaa tgaaaagacc ggggcaagca ttttactggc cagaatggaa aatccatctg
     2941 gcaacaggaa ggtgtgacgc gtaccgaaca caagtaggga agtcttcgta ggggctgtca
     3001 agaaaagccg ctattgtgtg atatgtgccc gtaccgtaaa ccgacacagg tggatgagga
     3061 gagaatccta aggccggcgg gagaagcatt gttaaggaac tcggcaaaat gaccccgtaa
     3121 cttcgggata aggggtgcct gagaaatcag gccgcagaga ataggctcaa gcaactgttt
     3181 agcaaaaaca caggtctatg caaaaccgaa aggtgaggta tatgggctga cgcctgcccg
     3241 gtgctggaag gttacgagga ggggttagcg gaaacgcgaa gctctgaatt taagccccag
     3301 taaacggcgg ccgtaactat aacggtccta aggtagcgaa attccttgtc gggtaagttc
     3361 cgacccgcac gaaaggcgta atgatttgag cgctgtctcg acaatgcacc cggtgaaatt
     3421 gaagtaccag tgaagatgct ggttacctgc gccaggacgg aaagacccca tggagcttta
     3481 ctccagcttg atactgggat tcggtactgc atgtacagga taggtgggag gcatagaagc
     3541 aaggacgcca gtctttgcgg agccgatgtt gggataccac ccttgcggta ttgggtttct
     3601 aacctgcagc catgacctgg ctgggggaca atgtcaggcg gggagtttga ctggggcggt
     3661 cgcctccgaa agggtatcgg aggcgctcaa aggttccctc agaatggacg gaaaccattc
     3721 gaagagtgca aaggcataag ggagcttgac tgcgacaccg acgggtggag caggtaggaa
     3781 actaggactt agtgatccgg tggtataaag tgggattgcc atcgctcaac ggataaaagc
     3841 taccctgggg ataacaggct tatcactccc aagagttcac atcgacggag tggtttggca
     3901 cctcgatgtc ggctcatcgc atcctggggc tgtagtaggt cccaagggtt gggctgttcg
     3961 cccattaaag cggtacgcga gctgggttca gaacgtcgtg agacagttcg gtccctatcc
     4021 ggcgtgggcg taggatattt gagaggagct gtccttagta cgagaggacc gggatggact
     4081 gacctctggt gtatctgttg gtgatcaaca ccatggcaga gtagccaagt cgggaaggga
     4141 taaacgctga aggcatctaa gcgtgaagcc cccctcaaga tgagatatcc catcgcaaga
     4201 gtaagacccc ttgaagacga cgaggtagat agggcagagg tggaagcatg gcaacatgtg
     4261 gagctgactg tcactaatag gtcgagggct taaccaggtt ggtttaggta agaggaaaga
     4321 acggatgaaa acagatatgt aacaatgtgt ggttttgagg gtatatgcag taaactatta
     4381 tgcataacac agaattttaa tgcgtaaatc cagatatggg tttgcgcttt tttcatatat
     4441 ataaaagctt cttatatgtg aggactccat tgctttgaaa agcattttaa ggtaaatgaa
     4501 gagagagaat taataatttt tacagagctt cagaataaat gcaggaaagt aaactatgaa
     4561 agaatttagg agatgtttgg aatgaagaga gagcagaatg ttattcggat actcatggtc
     4621 tgccttggca atatatgcag atctcccatg gcggaatttg tcatgaagga tataatagaa
     4681 aagaagcact taagcaatcg cttttttgtt gcatcagcgg ctactagcac ggaggagatc
     4741 gggaatccgg tgcatcgtgg gacaagagaa aagcttaagg aacatggaat taccactgag
     4801 ggtaaatatg cagtacagtt atccaggaag gattatgata aatatgatta tctcattggc
     4861 atggaacaga ggaatgtgac aaatatgctt aagatcctgg gtggggaccc ggaagaaaag
     4921 gtcagacggc tgatggattt ttccgttgct ccaagagata ttgcggatcc atggtacaca
     4981 ggggactttg accgtaccta tgatgatatt tatgaaggct gccaggcgct tctggcgtac
     5041 attctgaaga aggaatcgat aaaaaattaa agatagcagg aggatcttat atgaaaccgc
     5101 ttaattttat ggtagtaggc tcaggatgga gatccctgtt ttatgccagg atcgccaaag
     5161 cctatccgga tagttttaac ctgacggcat ttctttgccg gacagaagaa aaggccgtac
     5221 agatccaaaa ggaaaccgga atcaaggcgg taacaagccc agaggagtgt ctgtcagaga
     5281 aaccggattt cattgttgtg gctgtaaata aagattctat ctttcaggtg acaggggaat
     5341 gggcacggaa gggatatcct gtgctttgcg agactccggc ggccatgaaa ttggaagatc
     5401 tgcaggaact ttggcgcatt catacccagg aaggtgcaag aatccaggtt gcagagcagt
     5461 attttaagta tccggtcttt tctgcggcca ttgaggttgt aaagcgggga tatcttggag
     5521 aaccctatat ggtcaatctg tcggctgttc atgattacca tggagccagc ctgatcaggc
     5581 agtttttggg aaccggcttt gagaacatga aactatatgg aaagaaattt ctgtatcctg
     5641 tggtggaaac ggattccaga tatggacttg tggaagacgg cagaataagt gagagagaac
     5701 gggtcaggat gacgtttgaa tttgaaggag gaaaaaccgc tttttacgat tttaacggca
     5761 ttcaatacca ttccaggatc agaagccggc atttaaatgt tcagggagcc agaggggagc
     5821 tggatgactg gacgctgcgt tatgcaggaa aagacaaccg gtccagggag tttcagatca
     5881 taaaagaacc ttttgaaaca ggaaatggaa ttaagcaaat cactatgggg caggaactgc
     5941 tttaccgaaa cccgtttatt gatctgggaa aagccaatgg gcttcctcag gatgaaacgg
     6001 ctattggaac tcttatgctt gggatgcggc ggtttattga agaaggcgtg gaggtttatc
     6061 ctttggcaga gggattgcag gatgcctatg taaggatcct aatggagcag gcacttaaaa
     6121 gtggacagac agtagaatcg aaaacacagg tttggggatg aaagaaaagg agcaggcttt
     6181 ttccataagg ttaaaaaagc ccgctccttt ctgctttcaa aaaagaactt tcatatatca
     6241 tcatcgtcaa taatcgtaag attaaaggat tcacaggata agtcaacatc cctgcccgcc
     6301 ttctgatgag ggctgataaa gcggatgatg ggacggagag aaaatcccgg tgtgttatct
     6361 ttgacaaccg ctgagcttcc gtcactgaga tgaacaatgg taccgatggg ataggccgaa
     6421 acacaattca ggaaggcagt cagcagctcc gggtcaaaat gggtgttgga gcagctggtg
     6481 agataatcaa aaattcgtct gggagaccat gctttccggt acggtctggt ggaattgaga
     6541 gcgtcatata cgtctgcaat ggccaggatc cgggcataaa gaggaatatc cttacctgaa
     6601 aggccaaaag gatatccggt tccgtcaaat ttttcatgat gggtttggac tccctgtaaa
     6661 accgcctgtg aaatcaccaa gtgctcaccc agctttttat aggagagact tgggtgctgc
     6721 ttcatgattt caaattcacc gctggttaag gggcccggtt tattggtaat atcaatcggt
     6781 atatccgttt ttccgatgtc atgaagaaga ccacaaagtg ccaggtcatt taaattggaa
     6841 atggaaagtc caatatattt ccccaataga acgcttaaaa tgcctacata aaggctgtgg
     6901 gaataagtat aaccgtcata atccctgata tcaatcatct gaaagagata cttgtcctta
     6961 ttcaggacgt tcataacaac ggattcggcc actttggcaa tttctgcata cacctgtctg
     7021 ctggactgaa aagtaaattt ttttaagctt tggtcaaaga catcgcggat gcttgtgagc
     7081 attttggcct ttaattccgg ctccacaaaa tcttcgggct caatgccttc cgtaagcgct
     7141 gtgcagatat aagctccttg aattccgatt gttttcatgc ggttgatcat acgttcgctt
     7201 aatttgcagc cggtaactgc aaaaggaagc attgggttta ttcccgggat gtttcgggct
     7261 aattccatac cttcagtcaa tttctcaata ggaagataaa tcaattcttt cacctcaaca
     7321 gaccaaaacg cagtctcttc tttctgttcc tcaatttcct ttttatgctg tccgtaaatt
     7381 cctttttatg ttaaagttgg aaatatatac acaatgacac attaaattat agttggaatt
     7441 aacaaatgcg tcaatggaaa tttacatttt agacactcat atggcagaga aaaatctggg
     7501 gaaatttcgt gcaaaatact cattatatct tttatatcca ttaaaatttg agttgactca
     7561 gtcagggtca tagggtagtt ttaaagcaga agatcaaaga aggggaatct tatgattgaa
     7621 ataattctac caaaaaaaaa ctgtggggat aaccattcat acttgctgct cctcctgcat
     7681 aagtatgtaa aaacgtccta gcagggggat tttcttgaag gaatatattg aagaacgcgc
     7741 ggttgcgatc gccaactaca tcatagacta tcatgcgacc gtgaggcaga ccgcgaagaa
     7801 gtttgggata tccaaatcta cggtacataa agatgtgacg gaccgactgg agcacatcaa
     7861 tccgtccctg gcagcccggg ccagggtgat cctggacatt aacaaatccg agcgccatat
     7921 acggggcggc ctggcaacca aagaaaaata ccagcaccgt cttcagatgt gcagcaaaaa
     7981 gaattagcat aacaaaggag tgaaaacagc ttctgacggg actggaatca gattcccatc
     8041 agaagctgtt tttgaactgg aaaaaatttt agttgacatg aagcctaaaa atgtgttatt
     8101 ctttaccccg gtatgaagag acattatcgt tttcatgcaa atattgacca cttcgtagaa
     8161 gttaagccca gacggacagg cgggtcaggt gccgagcgtg ggaaaccaca ttattgattg
     8221 agttaaaagc tcaaatttta taagttgatt actttataat ccgtgcaata gcacatcact
     8281 tgtgaaacga tcaataatag cagggacaac atatttgcta tgtagactcg aaaacgataa
     8341 ttatcatgaa taaaaagggc agaatgctct tattggaaat acggttcatg aaattacagg
     8401 caggtgatgg cagatcacct gcctttttgc tgtgaaaaaa catgcgccca tcaggcgccg
     8461 ctttggcttc agtgacaaaa gagggagtgt tattcccgtg acaaggaaag gtaaagtcca
     8521 tatgaataaa aaagatcaga tgagggcgcc tatttatgaa gctcttgaaa cattccaaaa
     8581 aaaaagggtg gttccttttg acgtgccggg ccataaaagg ggaagaggaa atccagagct
     8641 tgccaggctt ttgggggagc ggtgtgtggg acttgatgta aattccatga aaccccttga
     8701 taatttatgc catcctgttt ccgtgatccg ggaagcggaa cggctgacag cggaggcttt
     8761 tggggcagca gatgcattct taatggtggg agggaccaca tcggcggttc agagcatgat
     8821 cctgtccgta tgcaaggcgg gagataagat catcctgcca agaaatgtcc acagaagtgc
     8881 cttaaatgcc ctggtattat gcggagcggt tccgatttat gtaaatccgg aagtgaacag
     8941 catgctgggc atctcccttg gcatggagat cggtcaggtg gaaaaggcga tccaggaaaa
     9001 tcctgacgca gcggcagtat ttgtcaacaa tcctacctat tacggtattt gctctgatat
     9061 tcgttccatt gtccgggtgg ctcatgccca tgggatgaag gtccttgcgg acgaagctca
     9121 tgggactcat ctttatttcg gaaaaggcct tccggtttcc gctatggaag caggggccga
     9181 tatggcggcg gtatccatgc ataagtcagg aggaagctta acacaaagct ccctgctcct
     9241 gttaaacaaa ggggtgaatg gagattatgt acgccagatc ataaatttga cccagaccac
     9301 cagcgcctct tacctgcttt tgtcaagcct tgatatatcc agaaggaatc tggctctgcg
     9361 gggagaagag tcctttgcaa aggtagtgga aatggcggag tacgccagag gagagatcaa
     9421 ttccatcggc gggtactatg cctatggaag ggacttgatc aatgggacca gtatttttga
     9481 ttatgatgta acaaagctat ccgtctatac cctggggaat ggactggctg gtattgaggt
     9541 ttatgatctc cttcgggatg aatatgatat tcagatcgaa ttcggagata tctgcaatct
     9601 ccttgcctat atctccatcg gtgacaggat ccaggatata gaacgcctgg tgggggccct
     9661 ggcggatatt gaacgccttt ataagaaaga cagagcagga atgctgtcgg gagaatacat
     9721 tgctcccaaa gtggcagtat ccccccaaaa ggccttttat tcacaaaaaa tatccgttcc
     9781 cgtaagggaa tccgcaggaa ggatcagcgg ggagtttgtc atgtgctatc ctcccggaat
     9841 tccgattctg gcaccggggg agatgattac agaagagatc gtggagtaca tcatttatgc
     9901 cagggaagtg ggatgctcca tgcagggaac cgaagacccg gctgtggaac ggctgatggt
     9961 attaaaggag cagatcaggg aaggggagag gtaggaacaa atggagatat ggttttcgaa
    10021 atttcacacc tccaatgtaa agctttccgt gcggatcgac aaacagcttt tttccggtga
    10081 aagtgagtac cagaggatcg acgtgtttga atcccaggaa tttgggaagt ttgtatcatt
    10141 agatggagat attgtttttt ctgaaaagga tgaatttatt tacgatgaaa tggttactca
    10201 tgtacctatg gcagttcatc ccaatgtaag agatgtgctg atcatcggag gcggcgacgg
    10261 aggggtggca aaggagcttc tgcagtatcc cctgatccgg tctattgatg tggttgagac
    10321 ggataagctg tttgtggatg tttgcaggga tatttttccg gaggtatcct gcggcctttc
    10381 tgacccccgg gtcaaggtct attacgatga cgggctccgt ttcttaagaa acaagaaaga
    10441 agcgtatgat ctgatcatca atgactccac ggaccccttc ggacatacgg aagggctgtt
    10501 taccaaggag ttctacggca gctgctataa ggcgctgcga agcgacggca tcatggttta
    10561 tcagcatgga agtccgtttt atgatgagga tgaggcagcc tgcaggagta tgcaccggaa
    10621 ggtataccga tccttcccca tcagccgtgt ttatcaggcc catattccta cctgcccgtc
    10681 aggctactgg ctgtttgggt tcgcatcaaa aaaatatcat cccgtcaatg actttaagcc
    10741 agcagcatgg aatcagttaa aaattgaaac atggtactat acaaccaatc ttcatacggg
    10801 cgctttcatg ctgcctaaat atgtggaaga tttactggaa gaggaggaaa aagaatgagc
    10861 agattattag ttatcgggtg cggcggggtt gcttcagtag caatccacaa atgctgtcag
    10921 aacagtgagg tgtttacgga catctgtatc gcaagcagga caaaggaaaa atgtgatgcc
    10981 ttaaaggata agcttgcagg aacaacaaaa accaggatcg agacggcgaa agtggatgcg
    11041 gatcatgtgg atgaggtcat tgccctcata aaggattata agccggatgc agtgttaaac
    11101 gtggcacttc cctatcagga tttaaccatc atggatgcat gtctggcaac aggggtggat
    11161 tatattgata ccgctaattt tgagcctgag aataccgatg atccggaatg gaaggcgatc
    11221 tatgagaagc gctgcaagga gcttgggttt accgcccttt ttgattattc ctggcagtgg
    11281 gattataagg agcgttttga aaaggccaat atcaccgccc tccttggaac cggattcgat
    11341 ccgggggtta ccagtgtttt ttccgcctat gccttaaagc attattttga tgagatccat
    11401 accatcgata ttctggactg caacggaggg gatcatggat atccctttgc caccaacttc
    11461 aatccggaaa tcaacttaag agaagtgtct tccaatggtt cttattggga ggagggccgc
    11521 tggattgaga cagagcctat ggagattaaa tccagatatc atttccctca agtaggggaa
    11581 aaggatatgt acctgcttca ccacgaggag atcgaatccc tggcaaagaa cattcctgga
    11641 gtaaagagga tccgtttctt catgaccttt ggacaaagct acttgaccca tatgaaatgt
    11701 ctggaaaacg taggtatgct ttctacctct cctgtgatgt ttaacgggca ggagatcgtg
    11761 cccattcagt ttttaaaggc cctgctccct gatccggcat ctcttggccc aaggaccaag
    11821 ggaaagacca acatcggctg catcttcacg ggagtaaagg atgggaagga aaagaccatt
    11881 tacatctaca acgtatgcga ccatgaggaa tgctacaaag aggtggagtc ccaggccatt
    11941 tcttatacca ccggggttcc ggccatgatc ggggccatga tggtggtaac cggccagtgg
    12001 aagaatccgg gcgtattcaa tgtagaagag tttgatccgg atccctacat ggaagcttta
    12061 aacaaatggg gacttccctg ggtagtatgc gaggacccgg aaaccgttac ggtatggaga
    12121 tagaaaaaga atgaggattg aggatttaaa gactccctgc tatgtgattg atgagggaag
    12181 gctggaaaag aacctggata ttttaaagaa ggtaaaggaa agtaccggat gccggattct
    12241 tctggcccag aaggcatttt cctgctttgc agagtatcct ctcataggca gataccttga
    12301 cggaacgact gccagcggac tttacgaggc caggctggga cgggaggaga tgggacttga
    12361 aactcatgtt ttcgctccgg catataagga ggaggacttt aaggagctga cggaaatctg
    12421 cgatcatatt gtattcaact ccttttccca gcttgaaaag tatcataatt ctttgggcgg
    12481 ggtgaaggcc ggcatccgga tcaaccccca gtgctctacc caggaaggtc atgaaattta
    12541 tgatccctgt gctcccggtt caagacttgg tgttcccctt gatcatttta aggaggagtg
    12601 gcttccctgg ctttccgggt tccattttca caccttgtgt gaacagaact ccgatgattt
    12661 aaaaaagact ttggatgcgg tggaggaaaa gttcggaaag tatttatccg gactgtcctg
    12721 gctgaacatg ggcggaggac atcacattac cagagaggat tacgacatcg gactgctgga
    12781 gacctgtata aagaggataa aggaaaaata cggcctgcag gtttatctgg aaccgggaga
    12841 ggcggttgct ctcaatgcag gatatctggt gacagaggtc atggatgtgg tggataacgg
    12901 gataaagact ctgatccttg acgcttccgc agcctgtcat atgcctgatg ttctggaaat
    12961 gccgtatcgg ccccctttaa aggacagcgg aaagccggga gaaaaagctt ttacctaccg
    13021 gctttcctcc tgcacctgtc tggcaggaga tgtgatcggg gattattcct ttgacaggga
    13081 attaaagccg ggggataagc tgtattttat ggatatggcc atttattcca tggttaagaa
    13141 caacaccttt aacggaatgc cccttcctgc catagccatt atggataagg aaggggactg
    13201 ccatgttata aaaaggttcg gctatgagga ttttaagaac cggctggcct gactgcccgc
    13261 ttgttcatta ggagacaaac tatggagaaa ttaaaaagcc tcccggcaaa agacgggttt
    13321 tacatgcctg gagaatttga gccccattgg ggctgtatca tgatctggcc caaacggccc
    13381 ggctcctggc ccttcggggc cggaaaagca aggaaggcct ttgcaaggat cgcagaggcc
    13441 atagcagaca gcgagcaggt gattatgctg gcagaggaag atgtagcgga aaatgcaaga
    13501 gagatgcttt ccggcaggat tcagattgct gtcatggagt ccgatgatgc atgggcaagg
    13561 gatgtggggc ctacctttgt tgtgaataag gaccgcaggg taagggggat cgactggcaa
    13621 ttcaatgcct ggggcggaac ctttgacggg ctgtatccgg actggaagaa ggatgacctg
    13681 cttgcagggc gtttttgcga gcgatttgga tatccggtct atgatgcggg gcattttgtc
    13741 ctggaagggg gctctattca ttctgacgga gagggcacgc ttttggtgac ggaaagctgt
    13801 ttattaagcc cgggccggaa tccttctctt acaaagcttc agatccagga gcagttaaaa
    13861 tgttatctgg gagccgtgaa agtcatctgg ctgaaagcgg gcatctatca ggatgaaacc
    13921 aacgagcacg tggataatgt ctgcgctttt gtccggccgg gagaagtggt cttagcctgg
    13981 acagatgatc aacatgaccc tcagtatgaa atgtccctgg ccgatttaag gattcttgag
    14041 aaagaaacag atgcagcagg aagacatttt aagattcaca agctcccaat accgaaaaag
    14101 ccggtctgca taacagagga ggagcttacc ggcctgtcct ttgagcctgg agaggatgaa
    14161 agggaggctg gtgagcgtct ggccgccagt tatgtgaatt tttatatatc caacggcggg
    14221 gtggtagtac cccagtttgg tgatgatcac gattcagagg cggttcgtat cttaggggag
    14281 tgcttcccgg agagaaagat ctatccggtg tatgcaagag atatcattgt gggaggcggt
    14341 aatattcact gcatcacaca acaaattccg ttgtagttca gcgatgtctt tgtatcgtga
    14401 tctgtaacgc agataccgga aggagggttt catgagaatg ataacagcgg cagcagttca
    14461 gatgaaatgc tgcgatgacg ttaaaaaaaa tatagagcat ggggaaaggc tggtaaggca
    14521 ggcagcggag gaaggtgcca atgtgattct tcttccggag ctgtttgaac ggccgtattt
    14581 ttgtcaggaa cggcggtatg acttttatga ttatgcaaaa ccggcagagg agaaccaggc
    14641 ggtaaagcat tttgcaggaa ttgccgctga gcttcaagtg gtcctgccca tcagttttta
    14701 tgaacagtct ggaaatacca tgtttaactc ggtggcagtc cttgacgggg atgggacaaa
    14761 tcttggggta taccggaaaa cccacatccc ggatgaccat tattaccagg aaaaatttta
    14821 tttcactccc ggagatacgg gcttccgggt gtttgatacc agatacggga aaataggcat
    14881 aggaatctgc tgggaccaat ggtttcctga gactgcaaga tgcctggcct tacagggagc
    14941 ggagctgatt ttatatccta cggcgattgg gagcgagcct attctggaat gtgacagtat
    15001 ggagcactgg aggcgctgca tgcaggggca ttctgcttcc aatatcatcc cggttcttgc
    15061 agcaaaccgg gtaggagtag aatccgtgat tccatgcatg gaaaatggga atcaatgttc
    15121 ctctctgaaa ttttatggtt cctcctttat cacggaccat accggggctc tggtagcatc
    15181 tatggacagg gaggaggaag gcgttatatg cgcttccttt gaccttgacc agttggcggc
    15241 cgaccggaga aactggggac ttttccggga ccgcaggcca gggatgtatg gggatatcag
    15301 caaaaaggcg taaatttatt cataaaaccg gcactctccc catatatata gtaataatca
    15361 ataagttggg gagtgtgcta tgaagagact gttaagcaga aaatggatga tttttttcgg
    15421 cctggccatg tgggtattgg ttgtacgtac tttaagcggg tgcactttta acggggataa
    15481 tggggataaa gtacgggata tggaacttac cgtggtagct gacgcggata ttccgcagga
    15541 acttagacag atcattgcgg agaagcagca gtcgcctttt aagctgacct acagcgatga
    15601 taagaatcta tacatagtag ttggttatgg aaaacaggcc agcggaggtt acagcatcgc
    15661 agtaaatgaa ctgtatttga cggataattc cattgtcctg gacacggagc tgatcggacc
    15721 ggaaaagggg gaaaatacgg ggacagaacc ctcctatcca ttcatcgtca ttcaaacaga
    15781 gatgtcggag cttccggtgg tgttccagta ggaaataagg agaaaacagc cgttccgcag
    15841 atggcaaatg cgggacggct gtttttgcgg ggataatatg gattcctacc gtggaaaact
    15901 gtaaattccc cttttttctt aggctgtcat atgatatact acttcaaaca ggaataggca
    15961 gtaaggaaaa gaggaagatc atatgatatt aaaggatata tggcttgatg tgtcagcagt
    16021 aaaggagcgg gatccggcgg ccagaagcaa gctggaggtg cttttgctgt atcagggagt
    16081 ccatgcgctg atttggcatc gctttgccca ttggttttac cagcacagga tgttttttat
    16141 tgccaggttt atttcccagc tggctagatt ctttacactg atcgagatcc atcccggagc
    16201 tcagatggga cacgggattt taattgacca tggctgcgga gtggtcatcg gagagaccac
    16261 ggtggttgga gataactgta ccatttacca gggtgtaacc ttgggagggg taggacttaa
    16321 caagggaaaa cgtcatccca cccttgggaa taatgtaacc gtaggcgcag gggcaaagat
    16381 cttaggatcc tttgaggtgg gagataattg taccatagcg gccaatgctg tgcttttaaa
    16441 gcctttggag agcaatgtga cagcggtggg aatccccgcc cgtgcggtga agatagacgg
    16501 cgtccctctt ccaaagaagg agagcaatct ggtgacaatg gaccattact gcaagatgga
    16561 ggagcgggtc agggatatgg aagaaacgct tttaaagctt cagaaagagc tttcatcgta
    16621 cagggaaaag gaaggggcga tccagacgga ggcttctcct gaagaacggt ctgaggaaga
    16681 aggaaacagg gaatagaagc ttttgaagcc tatgtttttc ctgaagtagt ggaatgggaa
    16741 caaaaaaagt ataatgaaac atgcacctgc ataaactttc ttaaaggaat aaagaaggta
    16801 aggcaggtgc ttttttatgt tggagctggt gaagaaaaac atacatatga atcgctggaa
    16861 aggatatgct acgtctcaga ttactcttga cgatgatttc atcgtccctg acagtatgga
    16921 tgacgtggat cagatgattt taagttccgg tgaaattacc attgattctg ttaaaaacca
    16981 gacagagcgt gtggtggtcc ggggaaagct ggactttatg atcctctacc ggggagcgga
    17041 aggagggctt cagacccttt caggaagcat taactttgag gaacccatca atgtgcccgg
    17101 actggaggaa agggatatcg tccagctggc atgggagctt gaggatttga acgcagggat
    17161 cattaattcc aggaagctga gtgtaaaggc aatcgtaacg cttaccgtga aggtagaaac
    17221 ctcctgcgac gtaaacgctg ccgtagatgt ggacacggga agcgcttcct ccgatgtgcc
    17281 tatggtggaa actctccgcc gcaatctgga tgtggtttcc gtagcgctcc gccacaaaga
    17341 tacattccgg atcaaggata ccactacctt gtcaggaaac aagccaaaca ttgatcatat
    17401 tctgtggacc gagatgaagc tgagaagcgt agccaccagg cccatggatg gaaaaatgat
    17461 gcttgacggg gaactgctgg tttttgttat ttaccaggga gaaggggaag gagcccccat
    17521 ccagtggatt gaggaaagta ttccgttttc aggagaactg gatgtgccgg atatgactga
    17581 ggatatggtt cccgtggtga cggtacattt gatccataag gacatagaag caaagccgga
    17641 ttctgacggc gagatgcggg aaatggatgc agacgcggtt cttgaattgg atatgaagct
    17701 ttacagggaa gagaatatgg agctgcttaa tgatttatat tccaccaacc gggagctgac
    17761 gctgcagaca ggggaagcct gttttgataa gatcctgacg aagaacatga gcaagtgcaa
    17821 gatcgtggag aaaatcagcc tggatcaggc ggaccggatt cttcagatct gccacagtga
    17881 gggagcggtc aaaattgatg atacggagat caaggaggac ggacttcatg tggaaggtgt
    17941 gatagaggtg cggattcttt atatgacctc tgacgacagc cagcctatcc agtcggcggt
    18001 ggaggatatc cccttccatt acctcattga ggcaccgggg atcaatgata agaccatctg
    18061 tcagttaaat ccgggcttag agcagctaag cgctgttatg atgggcggag gaaccattga
    18121 agtgaagtcg acgatttccc ttgacttact ggctctccag ccggtttgcc agcaaatcat
    18181 taccaatgcg tcggaagctc ccatggattt aaacagcttg cagaaacttc ctggaattgt
    18241 gggatacatc gtacagccag aagattctct ttggaaaatt gcaaaaaaat tccataccac
    18301 catagatacc atcatagcca ccaatggttt gacagataaa tccgtaaaac cgggggatcg
    18361 tctgattctt gtaaaagaat tgtcttaaaa tggaatgcca ggcagaagga ttcacttttg
    18421 cctggcatat ttggtttaga ctttgaatga tttttttaaa aaagggtaag ataaagattg
    18481 ctattcacat atcagcttgc cctgttatat aatatactat agctaagcta tagcttcaac
    18541 catcgatggc gccaaaacgc atccagctgg tgctttagat agatgacagg ttaccctgga
    18601 cggtagtgac gtgattgcaa ggcgttatta ccgtttacat atcctgaatt accgataccg
    18661 gagaatgaag atcatgaatt acacctatat tttaaaatgt gcggatgata ctctgtactg
    18721 cggctggaca aaccatttgg agaaacgcct gtccgcccac aaccagggaa aaggagcaaa
    18781 atacacaaaa gcgcgcaggc ctgtggtttt agcctattgg gaagaatttt ccacgaagga
    18841 agaggctatg cgccgtgagg ctgcaataaa aaagctttcc aggagggaca agctaaagct
    18901 catgggggaa attggatgag aaaaaccgtc aggaccgcaa aagcagggga ctgacggttt
    18961 tacccgttct aggcaacaaa atggtacatc aggatataat ggcacaggct tcctcccatg
    19021 acaaagaggt gaaaaatctc gtgggagccg aagcttttgt gtttggcgtt gaaaacagga
    19081 agcttcaggg cataaatgat accgcccagg gtgtagatga tgcctccggc cagcagccag
    19141 aggaacccgg caggagaaag agcatctatg atctttgtaa atgccagaac acacacccag
    19201 cccatggcaa tgtaaagact ggaagaaaac catttggggc acatgataaa gcaggcttta
    19261 atcagaatcc ctgtaacagc gattccccat acaagagcca gcaggcccca gccggtctca
    19321 tctcccagaa cgatcaggca aaccggtgtg taggttcctg caatcaggat gaagatcatc
    19381 atgtgatcta ttttttttaa cagacggttt atcttgggag agatatcaag ggtatgatag
    19441 atggtgctgg ctgcataaag aaagaccatg ctgatgcaaa agaccgttaa tgcggccaga
    19501 tgtagccttc cgtcggatga agccttaata agcagcgggg ttgcggcaac gagtgccagt
    19561 atcatggcga tgaaatgagt gatggcactg accggatctt tgattttaaa ttccataaca
    19621 aacctccttg tagaaaatga taacctatga tgtagtaatt aatactatgt atcacatctt
    19681 tattcactat actcttttag ctaaaaaaat gcaactgttt tttacggtat aaagttcaaa
    19741 aaggggtttg ccagaattga aacaataaaa tataatgaat agaggaaggg aagaaaggga
    19801 aaggaaggta tgaccgccct atgaatcaga cgattaaaga acttatggaa agaaaatccg
    19861 tccgtgtata tgaggaacgg gtcattgaac cggagaaaaa ggcggctatt ttggaagcgg
    19921 cgttacaggc ccccactgcc gggaacatga ccttgtattc catcattgac gtgacggacc
    19981 agaagcggaa ggaaacctta tcaataacct gtgacaacca gccatttatt gcaaaagcgc
    20041 ctttggtgct tgtttttgtg gccgattatc ataggtggta cgagttgttc tgccattatg
    20101 aggatgtggt cagaaaacct ggcctgggag atcttatgct ggcctgtgat gatgcactga
    20161 tcgccgcaca gaatgcggtt gtggcagcag aatccctggg cataggctcc tgctacatcg
    20221 gggatattat ggagcagtat gagacacaca gagatttgtt cggccttcct aagtatgcag
    20281 ttccggctgc aatggtagtc tttggatacc ctacaaagca gcaggcggag aggaagaagc
    20341 cggaacggct taggcctgag gctgtggtgt ttgaaaattc ctaccgccgt ttagatcctg
    20401 aggaattcac ccgggaactt aagcgtattc agggcaggga agaggatttt gaacactggg
    20461 taaaggcatt ttgcaaacgc aaatggaatt ctgatttcag cactgaaatg agccggtcaa
    20521 tggaggccat gatagagtca tggaagaaag aggagtaaag gaagccatgg agctaaacat
    20581 attatacgag gatgaagaga tactggtggc ggaaaagccg gtgggaatgg aatcccaatc
    20641 agccagatcc tttgagccgg atatggtcag cgaggtaaag aaacatatca acagattatc
    20701 cccaaagcaa ggggagccat atgtgggagt tatccacagg ctggacaaac cggtgggggg
    20761 cgtcatggtt tatgctaaaa caaaagacgc tgcagagtct ttaagcaggc aggtttccat
    20821 gcatcagatg gagaaaatct attatgcagt ggtttgtgga aaacctgtgg aaaactttgg
    20881 agcatacgtg gattatttgt ggaaggacgg aaaaaataat tgttcaaaaa ttgtggataa
    20941 ggggataaaa ggtgcaaagc ttgcagaact atcctaccag attgtggatg aacggagcat
    21001 agggaatgag gtatgcagcc tggctaagat cattttaaaa accggccgcc atcatcagat
    21061 ccgggtgcag atggctggcc atggaacacc cctttgggga gaccaaaagt ataatcctct
    21121 ttttcagaag ggataccgca gcggtaatgt ggctttgttt gcttacagcc ttacctttac
    21181 ccatccggtt acgaagaaac ggatgacttt ttccgtaaaa ccaaagggag atatttttga
    21241 aacgttctta ttgccggaaa tggcataaag aaggaatttt ttactaaaga gatttcgcat
    21301 attttcattc cctacggctc ataatagtga ttgtacaaaa gaagtacaaa tcagaaacag
    21361 gtgagtccat ggtgaaaccg agcaggaaac tgaagaaaac attattaata ttgggagtta
    21421 caggggcagt gtatttcagt tttcgatatc tgctgcccct tgtgattccc tttttgattg
    21481 cctatgtatt tgccctctct cttcggcctt cggctctttg gattgagaga aagacccgtt
    21541 ttgccataaa ggggcgggag atttccgttc cccttgcaat gatcggaggg attgagatca
    21601 tccttttcat gatcgtcttt ggaattatcc tttacgtagg aggaagaaag atattcatgg
    21661 aagccaggct tctgcttcag aatcttccgg taatcctggg agaaatcgac cggtggctta
    21721 tggataactg ttcttttgcg gagcggtttt taaaactgcc tgacggatat atggtagagg
    21781 tggtaagaga tattatctca ggaggccagg ttgccataaa aggcagaatc atgccgtttc
    21841 tcatggtgaa ttccatgacc ataatgaaat ggatggttca ggcaacagtg atcctcatta
    21901 tattgctgat tgccacagtc ctttcccttc aggaaatgga tgagatacgg gaaaggcggg
    21961 ataattccat attctgcttt gaatatgcca tgcttgggag aagactgacc acggtgggaa
    22021 gtgcctggct taaaacacag ggagccatta tgctgtttac catggtggta tgttccatcg
    22081 ggctgtttct attgggaaac ccctatttta tccttttcgg aatcgggatc ggacttttgg
    22141 atgcccttcc catctttggc acagggaccg tattcattcc ctgggctctt ttttccatga
    22201 tcaataaaaa ctggaaatat ggaaccgggc tgattctcat ttatgttatc tgttattttt
    22261 taagggaaat tatggaagca aagatcatgg gaggcaaggt aggacttacg cccttggaaa
    22321 ccctggcttc catgtacgtt ggactgcagc tcttcggact tcttggattt atccttggtc
    22381 ccattggctt attgattgtg gaagatattg tggaagtata tgaggtttca tattgtcatg
    22441 acggaaaaaa gggagctgat ccggaggagt gatacaaaaa tttgttccgt cctgtgcagg
    22501 caagcgttga cctacttgac aaacatttgc aaataacgta aaatcaacca tacaatcttt
    22561 tttataatga agaaacaaga cgttgaagag gatcagtaag tgatgatgta ttccagagag
    22621 aaggccggat ggtggaaggc ctttatacct ctcatgaccc aacctccctc ggagtcccgc
    22681 agcaaactgc ggcgcagtcc tgcgttatgg gagataaagt gagtcatggc attctatggc
    22741 taaattgggt ggcaccgccg agctgttcgg tccctttcgt gggaacgaac ggctcttttt
    22801 gctttatcaa agtgtctgtc tgcaggaatc tcatgattcg ccaatattgc ggacaggaaa
    22861 atagaatgtc attatgtccc ggaagttggg cagaaaatag gagaggagaa ttagttatgg
    22921 ctaaggacaa gaaattagta gaagcgatca catccatgga tgtggatttc gctcagtggt
    22981 acacagatgt agtaaagaaa gcggaattaa tcgattattc cagtgtaaaa ggctgcatgg
    23041 ccattaagcc ggccggttat gccatctggg aaaatatcca gagcgagctt gacagaagat
    23101 ttaaagaagt aggggtggaa aatgtctaca tgcccatgtt tattccggag agcctccttc
    23161 aaaaggaaaa ggaccatgta gagggatttg ctcctgaagt ggcctgggtg actcatggag
    23221 gtttggagcc gctgcaggaa agactttgtg tc
//
