LOCUS       NC_014376.1            23460 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_014376.1 [Clostridium] saccharolyticum WM1, complete sequence.
ACCESSION   NC_014376
VERSION     NC_014376.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:47:57
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 326199
            Orig. end    :: 349659
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23460
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[336199:339659]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13460
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..23460
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23460
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(1726..2877)
                     /locus_tag="ctg1_305"
                     /transl_table=11
                     /translation="MSNSALQIDLNTSVSIGPGSNVLFDSIVYLSGNIGYDPSTGNILI
                     LEAGRYIIHWWLATQSSSSTNGSAFAISSSQGDFIIGNSPIKTGEVYGVGIIEVTDPPV
                     TFSLVNISTSTIYFSQNVPLKGTLVVLENAENGAIGPTGPTGPIGPAGPTGPTGAAGVT
                     GPTGPSGTTGPTGDTGPIGPTGPTGATGPSGTTGPTGPTGAAGPTGPTGATGPTGATGP
                     MGSTGPTGAIGPTGPTGPTGPIGPTGPTGPTGITGDTGPTGPTGPIGITGDTGPTGPTG
                     PIGITGDTGPTGPIGLTGDTGPTGPTGPIGLTGDTGPTGPIGLTGDTGPTGPIGLTGDT
                     GPTGPTGLTGDTGPTGPTGLTGDTGPTGPTGDTGPTGPTGPVI"
     CDS             3291..3668
                     /locus_tag="ctg1_306"
                     /transl_table=11
                     /translation="MNIRVIAVDNSEELLIKLTRILKEIDGVELCGSFHEAITAMQYVR
                     ENPVDLVFSDVVMPDISGITLAAKLYEHPDPPEVVLLSGIPGFSLEAWKIRAFGFIIKP
                     YTKMQIVKMIDQYIMEKNRVV"
     CDS             3668..3766
                     /locus_tag="ctg1_307"
                     /transl_table=11
                     /translation="MQRKTAYGSIYSNNDTGFYQKGFLRFFRAKAL"
     CDS             3897..5957
                     /locus_tag="ctg1_308"
                     /transl_table=11
                     /translation="MKEKFKIKGQLRMYMQWPLYLSALLIAANTVIGAASTKAGIIMAA
                     FTLLYIGIAVWLYTYRRRLLMGGLVEFSAEYSWMQKQLLTDLELPYGMADENGRILWGN
                     TAFSEVLGEEKPLKTSRKNIMAFFPEITKEVLKLNEGTAVVHVARNGRMYRIRLKAVKM
                     KDSPEVIVSSIGAEAAGQMLVAVYLFDETEILTYKQMVDDQKMVAGLIYLDNYDEALES
                     VEEVRRSLLTALIDRKITKYITNMNGIVKKLEKDKYFIAIKQSYITELKENRFSILEEV
                     KTVNIGNEMAVTLSIGLGMNGESYYRNYDFARIAIDMALGRGGDQAVIKDGERIQYFGG
                     KAQQVEKTTRVKARVKAHALRELMETKDRLMIMGHRLTDIDAFGAAVGIYRIATAMDKK
                     AHIIINEVTTSVRPMLDRFVGNPDYPDDLFLTGAKAAELADANTLLVVVDVNRPSITDA
                     PELLRLIKTIVVLDHHRQSSEIIDNAVLSYVEPYASSSCEMVAEVLQYIADGIKIKSPE
                     ADALYAGIVIDTNNFTNQTGVRTFEAAAFLRRNGADVVRVRKMFRDNLDDYKAKAEAIR
                     DAEIFEGCFAISVCSSEGIGSPTVIGAQAANELLDIAGIKASIVITDYNHTVYISARSI
                     DEVNVQVMMEKLGGGGHRTIAGAQLAEVSIEEAKIRVKAVIKEMLEKGDIS"
     CDS             5957..6403
                     /locus_tag="ctg1_309"
                     /transl_table=11
                     /translation="MEVVLLEDVKALGKKGQIVKVNDGYARNFILPKKLGIEATAKNLN
                     DLKLQKANEARLAEEQLEAAKALGAQLSEGSVTLSMRAGEGGRAFGSVSGKEISIAIKN
                     QLGYDIDKKKLILSEPLKTFGSHEVPVKLHKDVTAKIIVKVVES"
     CDS             6415..7749
                     /locus_tag="ctg1_310"
                     /transl_table=11
                     /translation="MDDALIKRVLPHSIEAEQSVIGSMLMDRDAIITASEIVTAGDFYQ
                     HQYGIMFEAMLELFNENLPVDLVTLQNRLKEKDVPPEVSSLEFVRDIITTVPTSANIKS
                     YANIVRNKAVLRRLIKANEEIANTCYAGKEPLETILAVTEKTIFDLLQNRNSGDFVPIR
                     QVAMNVLEKIEEASKNQGTVTGIPTGFIDLDYKTSGLQPSDFILIAARPSMGKTAFVLN
                     LVDHIAVKKGLPAMVFSLEMSKEQLVNRMLAMESNVDSQKLRTGTLSDSDWDAVVEGIG
                     VIGNSKLIIDDTPGISIGELRSKCRKMKLEYGLSVVIIDYLQLMSGSGKSGDNRQQEIS
                     EISRSLKGLARELNAPVIALSQLSRACETRQDHRPMLSDLRESGAIEQDADVVMFLYRD
                     DYYNKDTDMPNIAEVIIAKQRNGPIGTVNLVWRPEYTKFANMAKQ"
     CDS             8088..8747
                     /locus_tag="ctg1_311"
                     /transl_table=11
                     /translation="MAEIHYLISDASRKVDVESHVLRYWEDELELKIPRNEMGHRYYTE
                     AHIRLFKQIKDLKEKGYQLKAIKTALDKVIEDGRDPVIPDELLEGQVAQELKDSAISGT
                     EDGAGLEVHNTAPISIAQEKMEQFQEIMNHIIGRALEVNNEQLSQDVSSLVNDKVIKEM
                     EYLMNLKEEKEEERFKQLDELMRSYQKDNKGRAEAAASRIPFFNRKKKFGRNGKKL"
     CDS             complement(8850..9563)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C26"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_312"
                     /sec_met_domain="Peptidase_C26 (E-value: 4.6e-64, bitscore:
                     214.1, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKPLIGLTPAHDTENGDIKTRPTYVRALKAAGAIPVVMPLDASE
                     EDLKQLSQDLDGFLFTGGPDVHPFLFGEETQAHCGNVSPARDQMEITLLPMIMELKKPV
                     LGICRGIQVLNIALGGNIWQDIPSQVTREFPLAHTQPFHYDMPCHTVSLTKGSLLAQIS
                     GSSSIKVNSMHHQAVKDVAEGLIASAYSPDHLIEAVEMPGYPFFIGVQWHPEYLWEKNE
                     EAFRLFQTFVNACKE"
     CDS             complement(9741..9911)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_9"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1020:4Fe-4S binding domain (Score: 37.5; E-value:
                     4.2e-12)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_313"
                     /sec_met_domain="Fer4_9 (E-value: 2.7e-10, bitscore: 38.2,
                     seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.3e-07, bitscore: 29.1,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 8e-07, bitscore: 26.8,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5e-05, bitscore: 21.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARVISDACVSCGSCEAECPVSAISQGDSQFVIDADTCIDCGACE
                     GVCPTGAISEA"
     CDS             complement(10001..10774)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 84.2;
                     E-value: 3.4e-26)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_314"
                     /sec_met_domain="Radical_SAM (E-value: 2.1e-31, bitscore:
                     107.5, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGYIHSIESFGTVDGPGVRMVIFLQGCPMRCQYCHNPDTWKMAG
                     GTPMTAEELLKQFESSRNFYRGGGITATGGEPLMQLDFVTELFEAAKKKDIHTCLDTSG
                     VMFHRNGPDYLNKIDRLLEHTDLVMLDIKHMDDPKHKVLTGQSNENILDFARYLSQKEI
                     PVWIRHVVVPQITDQTPDLYRLGRFIGELKNVKALDVLPYHDMGKVKYESLGMDYPLKD
                     TPPMSKEGAIAAKKIILSGIRDVRTGVPDRYCSQF"
     CDS             complement(10798..11043)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_315"
                     /sec_met_domain="Gly_radical (E-value: 1.1e-26, bitscore:
                     91.4, seeds: 99, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANISESQINNLVNLLDGYVEEGGHHLNVNVFTRDTLIDAQKHPE
                     NYPQLTVRVSGYAVNFIKLTKEQQDEVISRTFHNNM"
     CDS             complement(11072..11341)
                     /locus_tag="ctg1_316"
                     /transl_table=11
                     /translation="MADPKEKQIEDIVSMLDQFMAGNGGHMNIRVSEDGIVSTDKTMAK
                     SVTTMNSTDCSDGNSACRVPTLFEAMDTEEEDPESNRLFMEDTF"
     CDS             complement(11400..13460)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_317"
                     /sec_met_domain="Gly_radical (E-value: 3.1e-12, bitscore:
                     45.0, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 3.8e-277, bitscore:
                     918.5, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTEWRAFTGGVWEREINVRDFIQKNYTPYDGDDSFLAGPTTATN
                     ELWAQVMDLSRQEREAGGVLDMDTKIISTIVSHGPGYLNKDKETIVGFQTDKPFKRSLQ
                     PYGGIRMAEKACADNGYTIDPEVREFFTIHRKTHNAGVFDAYTQEMRDCRSNHIITGLP
                     DAYGRGRIIGDYRRVALYGIDRLIEDKEEQKATTRTIMYSDVIREREELSEQIRALKEL
                     KKLGSLYGFDLSKPAANAKEAIQWMYFAYLAAVKEQNGAAMSLGRTSTFIDVYAQRDLE
                     EGTFTEEDIQEFVDHFIMKLRLVKFARTPEYNELFSGDPTWVTESIGGVGIDGRHLVTK
                     TSFRYLHTLKNLGTAPEPNLTVLWSTKLPANFKRFCAKTSIESSSIQYENDDLMRVTHG
                     DDYAIACCVSSMRVGKEMQFFGARANLAKCLLYAINGGIDEVTKKQVGPKYRPITSEYL
                     NYEEVMDAYKDMMKWLARVYVNTLNIIHYMHDKYSYERIQMALHDKKVIRWFATGIAGL
                     SVVADSLSAIKYAKVKTVRDENGIVTDYIVEGDFPKYGNNDDRVDQIANELVHTFMNYV
                     KGNHTYRGGIPTTSILTITSNVVYGKNTGATPDGRKKGEAFAPGANPMHHRDTHGAVAS
                     LASVAKLPFRDAQDGISNTFSIVPGALGKEDQIFTGDLEVDLELALNEDQV"
     CDS             13713..13913
                     /locus_tag="ctg1_318"
                     /transl_table=11
                     /translation="MQIQKDMLIGALLEMDENIAPMLMRAGMHCLGCPASQGESLEEAC
                     QVHGIDCDVLVSQINEVLADR"
     CDS             complement(14126..15448)
                     /locus_tag="ctg1_319"
                     /transl_table=11
                     /translation="MVKITFMGAGSTIFARNVLGDCMCTPVLSDAQIALYDIDPVRLAD
                     SELILNAINKNVNQGRADIKTYLGVENRKKALSGATFVVNAIQVGGYDPCTIIDFEIPK
                     KYGLRQTIADTLGIGGIMRGLRTIPVMEDFARDMEEVCPDAYFLNYTNPMAILTGYMQR
                     YTSIKTIGLCHSVQVCSETLLKELDMEDKLEGRTELIAGINHMAWLLKLHDKAGNDLYP
                     MIRQKALEKNQMEKHKDMVRLEYISHLGYYCTESSEHNAEYNPLFIKSGYPDMIDEFQI
                     PLDEYPRRCIKQINEWEAEKNSILNHGEITHTRSREYASYIMEAILTNKPYKIGASVLN
                     QGLIHNLPADACVEVPCLVDGSGITPCHVGRIPTQLAAMNMTNINPQLLTIEAAHTRDR
                     KTIYQAAMLDPHTAAELSLKDIRSMVDELIEAHGDYMKMYR"
     CDS             15566..16363
                     /locus_tag="ctg1_320"
                     /transl_table=11
                     /translation="MNQSARGLTIYYCGREQCASGHFFGPAIRKHYLMHVVLGGKGLYR
                     AGGMEYALKEGDAFLIKPQEVTYYQADKDEPWEYAWAAFAGTEAERLLSDYRQDENGYV
                     YHFSHGEEWRTSIVQLADAFQRGGHNMDEMAGYLYLLFSRFPMQDREGGEYEKSYLSRA
                     EGYIRHNYSYPIQIGDVANYVGIDRTYLYRLFMKYKSISPKQYLTAYRIMEAKRLLEET
                     GLSITEAGLSCGFHDASVFCKSFLKTEGESPLQYRKKIRKEIR"
     CDS             16743..17321
                     /locus_tag="ctg1_321"
                     /transl_table=11
                     /translation="MVLHSLEDTEHSVIKIINGHHTGRTEGMPITDLALQMLEEIEKDG
                     EKSYISYFTKNKKEEPLKSSTIVVRGEERRIIGLLCINFYLNTGFAQILNSYIPQISTH
                     SLVKTETFANNLDELIFGKVQEVRNAVMEDDGILPSLKNKEIINSLHQQGVFTLKDAVV
                     KVADYLGISKNTVYMHIRNAGVNTEKKNE"
     CDS             17523..18737
                     /locus_tag="ctg1_322"
                     /transl_table=11
                     /translation="MEESKKSKKGLGLVPRLIIAIIIGILIGKYCPSFVTSILITASDL
                     FKQFLMFIIPLMVVAFVTMGIADLSQGAGKLLAFTAAVSYASTLLAGSAAYAVASTFFP
                     SFVNEEVVAKVASASDKAISGYFSLTITPLLETTAAVALAFVLGVCISTMRGKEIGDAL
                     YNVIKEFAEIITKVLGRVIIPLLPLYICGTFAKMTYQGTTFAIMSVLWKVFLIVILLHL
                     IYLLAAFGLAGILTKRNPVTMLKNQVPGYLTAIGTQSSAATIPVNIKCAESNGISEEIR
                     NFVIPLCANIHMAGSMITITCCVTATLLIYGMSHGFLTLFPFICVLGIALVASPGAPGG
                     SIFTATPFFPIVGIPAVGDIASLLQAMYIAQDSFGTACNVSGDNAISALVDMYYHKYIK
                     KDNLG"
     CDS             18765..19433
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SDH_beta"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_323"
                     /sec_met_domain="SDH_beta (E-value: 1.5e-12, bitscore:
                     46.2, seeds: 368, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSISIFDVIGPNMVGPSSSHTAGAVAIALLVKKMFNGPIKKVEF
                     VLYGSFAKTYKGHGTDRALLGGILGFETYDLRIKNSFQLADECGLMYSFCVDEKETEVH
                     PNTVEIHVTGENAGTMSVRGVSLGGGKVKIIRINGIDVDFTGEYSTLVIRHLDYPGMVA
                     YIATSLSERNVNIAFMRLFRERKGATAYSVVESDEEIPQELLEKLREHPKVEDVMLIQV
                     "
     CDS             19443..20321
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SDH_alpha"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_324"
                     /sec_met_domain="SDH_alpha (E-value: 1.9e-73, bitscore:
                     245.3, seeds: 645, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFISGNELLKLCEENQCRISEVMREREASEFGASSQETISRMKE
                     AYRIMKESCHKPLDEPVVSIGGLIGGESAKVRDRRRSGKSICGSMLSKAITYSLAVLEV
                     NASMGLIVAAPTAGSSGVLPGLLLALEEEFSLGSDQIIDGLFTASAVGYLFMRNATVAG
                     AQAGCQAEVGAASAMAAAAATEIMGGTPQQCMDAASSALVNLLGLVCDPVAGLVEYPCQ
                     NRNVLGAANALVCAEMALSGVKQFIPFDQMLDTMMAVGRSIPFELRETSLGGCAITEAA
                     CGRACEIFQSK"
     CDS             20470..20919
                     /locus_tag="ctg1_325"
                     /transl_table=11
                     /translation="MNEHREIGKYISILQRLNNMYFANQLSFYQIGCGQQFFLLQIYKN
                     PGMSLHELASFGHYDKATATRAVKKLEEEGYVLTEMAKEDKRLRRIYVTDKAAAVVEKT
                     LESVAEWADIILKGFTKEERDAAEQMLIRMAYNASHHIMEQKGKE"
     CDS             20928..22316
                     /locus_tag="ctg1_326"
                     /transl_table=11
                     /translation="MEQNKMKQGENPLGYKPVGHLLLQFALPAIIAMLVNSIYNIVDQI
                     FIGQGIGYLGNAATTIAFPIVTIILAISTLLGAGGSAYAAIKLGEKNEKEADKTLGTVF
                     AVTLAASVVVMAVAFPLMTPMLKVFGATENTMGYARQYTSVILMGTPFNMLSVVLSNMA
                     RTDGNPSLSMYAILVGAVLNTILDPVYIFVFHWGVTGAAIATITSQIISAVVLVHYFIF
                     KGKHMRLHRKGLSIDGKICRLALPLGISSGITQVASTILQVVMNNSLVYYGNQTDIGGD
                     VALSAMGVVNKIGMILISICIGIGIGSQPILGFNKGANQPKRMRRTFLLAAGAATAVSI
                     TGWLACQIFPGQILSLFGTKDVLFTQFAIRCLKIYMLGIFSAGFQVVTTSYFQSTGQPL
                     KASVLSMLRQLLLLIPLILTLPLTFGLEGILYAGPAADITSMIIVSQFVLYEMRKLNRF
                     CKDT"
     CDS             22386..23276
                     /locus_tag="ctg1_327"
                     /transl_table=11
                     /translation="MSMKTEMARIFAGLNKSDRKMALELEHPARGTAALDQERFTKRVR
                     VKAWNVDGFPAFTINGSYTKAAHVLMLPGGAYTLEPSGRYREMAEHFAIEKQVRVTIPL
                     CPLAPEYTALDAHRYLVRVYSFLAAEYPEDEFFLFGDFSGGGLALSLLQELRDTGNLPM
                     PVRTAVVSPWLDIALSNPKIKIVKKSDPILPVEALKEAGVRYRGPLEPDHPFVSPLYGN
                     WDHLGQILVFSGTEEILTPDCELLAEMAGKLQGTEIIYRKGARMIHDWILIPCKETDAT
                     LDLIFAFFLEEALGF"
ORIGIN
        1 tttctatact tttaatgaaa agagcattga ccttagagat aagcgtactg ttgatagttt
       61 tgtaagtgat attcgtgctc ctgaaagcgg agtagcacct attaaaagca tttgtgaatc
      121 agaagtcttt agtgaacagt atttgccgat tgacctgcct gctttttcag gagttttata
      181 tacatggaga catagaaaaa atgatgacct tgaacaatgg ccggtaggtg tcaggatata
      241 cattaacaac tatagcttat ataggtatct agataaagaa aatgattggc tcaccctttc
      301 agaagtaagc caaaatgtta aagctactaa ctacaaatta aaaaacacat atgggtattt
      361 agatttaact aattacaatg aacataacca tgaattaaaa atatccaagg aacgaaatga
      421 tttcgtagat tcaatggctc aaagaaaatt catacatatt atgcgtgacg ttattgtggg
      481 aattttttca aggattgata tagcagttaa aaacccacct attcaatcaa ttaatctaag
      541 atataataat gtaacagtga aagttggaga accatttaat ttagcaaatg cagttatttg
      601 taataacatc ggactggatg atattgattt ggatttcgat gagtctcaaa tctctataac
      661 cgaagattgg atggtttcaa ctgatcgagc tggctcttat aatattaaat taaattttga
      721 tagtaaatca cacacattca caattcatta taaaaatgta attcctgaat ttgatttaca
      781 aaaaaacatg attacgatat ataaaggtaa ctcagtaaac ctaagagatt tcattgtggc
      841 ctcaagttgt aaggatgtta ctcctaacag catagatata cagtcgcagg gtaaagatac
      901 gattataaaa aatgatgtat tcgacaagaa taattcagtt ggtcaacata ttgtatttta
      961 tcgctatgag gattttcagc gtacattgtc aattactgtt aaagaaatag aacgtcaacc
     1021 tggtgctggt gcaaaatctc ctagaataga tattttattt ccaaagcttg atgatttacg
     1081 agcacattca tttaaactac ctgaattagt cgatgctata tcatcttatt atgtacaagc
     1141 accaaccctt tgtatggcgg caattcggat attaattgaa tcatctgcta aagaattttt
     1201 tgaacatctt gtagatgaag aggtaattga tagttttccg agtttggtta ataggatatt
     1261 gaatattcgc gattgccatc ctaaaagtcc agattatata aaatatatta gtacgcaaag
     1321 cccaagattc attgaggaat atcagcgtat atccactgaa taccagcttc tcttatctaa
     1381 agatgtaaaa acaaacataa acgctcacct taaagaaata gatcttgaca tgtttgtaca
     1441 caatccatca attgttgcaa ctgacacaac ggtatatagg tctatgcaaa tatttgcccc
     1501 tttgttgaat tatatttttg aagttttatt gctcgatctt tcataactat aaataaaatg
     1561 tattttagat ataacttcgg gccaacttgg ctcgaagtta tatctctata tacaaaaata
     1621 ccgcccatct tgtccaatta ggcagtatcc tgtgtaatgt gatagctcat attttatttt
     1681 ggtattccct tatcccgcat agaataaggt tttttgcagt tttccttaaa tcacgggtcc
     1741 tgtaggtcca gtcggcccgg tatcaccggt cggtccggtc ggtccagtat cgccagtaag
     1801 tccggtaggt ccggtcggcc cggtatcacc ggtaagaccg gtaggtccgg taggcccagt
     1861 atcaccggta agcccgatag gtccggtagg tccggtatca ccggtaagac cgataggccc
     1921 ggtagggccg gtatcaccgg taagtccgat gggtccagta ggtccggtcg gcccagtatc
     1981 accggtaagc ccgataggtc cggtaggtcc ggtatcaccg gtaattccga taggtccagt
     2041 cggtccggtc ggcccggtat caccagttat tccgatgggt ccagtcggtc cggtcggccc
     2101 ggtatcaccg gtaattccgg tcggcccagt cggcccggtg ggtccgatag gcccggtagg
     2161 tccagtcggc ccagtcggcc ctatggcccc agtaggtcca gtagaaccca taggacccgt
     2221 agcaccagta ggcccagtgg caccggtagg cccagtaggc ccagcagcac ctgtcggccc
     2281 agtgggccca gtggtaccgg aaggtcctgt agcaccggtg gggccagtag gtccgatagg
     2341 ccccgtgtca ccagtaggcc ctgtagtacc ggaaggccca gtgggccctg taacaccggc
     2401 tgccccggtc ggtccagtag gtccggcagg accgataggc ccagtaggtc cggtaggtcc
     2461 gatggctccg ttttcagcat tttctaaaac aaccagagtc cctttcagcg gaacattctg
     2521 agaaaaatat atagttgatg tactgatatt cacaagtgaa aaggtaaccg gtggatccgt
     2581 tacttcaata attccaactc catatacctc acctgttttt attggagaat tgcctattat
     2641 aaaatctccc tgtgatgaag atatagcaaa agcagaccca tttgtagatg atgaagactg
     2701 tgtggctaac caccagtgga taatatatct tccggcttca agaataagga tattaccggt
     2761 ggatggatca taaccgatgt ttcctgaaag atatacgatt gaatcgaaga ggacatttga
     2821 tccgggtcca attgatacag atgtatttag gtctatttgt agtgcggaat tgctcattgt
     2881 atttcctccc catacttttc taaatcaaaa aactacagtg cacaaacatg cctgttatat
     2941 attttatgcg gtagacaagg tttaggaaac tgttcgtgct tttcatgcat ttacagaact
     3001 tattcccaaa tttccatttt tccaggcaat taataagagc aagtcaaaat attaaaagga
     3061 aatggaataa gatggatgga aacaggatat gaataaattt gttcctaaga aagaaaaaca
     3121 aatgaagaaa acttttaacc ggaggtcagt taatctgatg attattttgt agttgcgatg
     3181 aatcgattaa tcatggttta ttgatgtccc ccgttgaaac aatatgcatt tttaagtata
     3241 atagtttcat tacacttaat gaaaaaagta aaaggaacca gggaggcatt atgaacatca
     3301 gggtcatagc agtggacaac tcggaggaat tattaataaa actgactcga atattaaagg
     3361 aaatagatgg agttgagctt tgcggcagct ttcatgaagc cataacagcc atgcaatatg
     3421 tgagagaaaa tcctgttgat ttggtatttt cggatgtagt catgccggac atcagcggaa
     3481 ttactcttgc agcaaagctg tatgagcatc cggatccgcc ggaggtggtg ctgctttccg
     3541 gaatacccgg tttttcgctg gaggcatgga agatccgggc ctttggtttt attataaaac
     3601 cctatacaaa aatgcagatc gttaaaatga ttgatcaata tataatggaa aaaaacagag
     3661 tggtttaatg cagagaaaga cagcttacgg cagcatttac agcaataacg atacaggttt
     3721 ttaccaaaag gggtttttgc gttttttccg tgcaaaagcc ctttaaaatt tgtttcaaaa
     3781 ctacggaaag ccttgtattt ccttagtttt tgtattttaa tggacgaacc cagatgacta
     3841 tgatataata ttaagatagt gaaaaagaga accctttttt ccataaggag aaagaaatga
     3901 aagaaaagtt caaaataaag ggacagctaa ggatgtatat gcagtggccg ctttacctga
     3961 gtgcattgct gattgccgcc aatacggtga tcggtgcagc cagtacaaag gcaggcatca
     4021 tcatggcggc ttttacactt ctgtatattg gcatagcagt ctggctttat acttacagaa
     4081 ggagacttct gatgggcggc cttgtggaat tttctgcgga atattcctgg atgcagaagc
     4141 agctccttac cgatctggaa ttgccatatg gaatggcgga tgagaacgga agaattctct
     4201 gggggaatac ggcgttttca gaagttttgg gggaagaaaa gcctctgaag acttcaagaa
     4261 agaacattat ggcctttttt ccggagataa ccaaggaggt gctaaagcta aatgaaggca
     4321 cggctgttgt tcatgtggca cgcaatggaa ggatgtaccg gattcgctta aaggctgtca
     4381 agatgaagga ttcgccggaa gtcattgtct catccatagg tgcagaggct gccgggcaga
     4441 tgcttgtggc agtttatctt tttgatgaaa cggaaatcct cacctataag cagatggtgg
     4501 atgatcagaa aatggtggcc ggtcttatat atcttgataa ctatgatgag gcgctggaaa
     4561 gtgtggagga ggtacgccga tctctgctaa ctgccctcat tgaccgtaaa atcaccaagt
     4621 acattaccaa catgaacgga atcgttaaga agctggaaaa ggataaatat tttattgcca
     4681 ttaaacagtc ctatatcaca gagcttaagg agaaccgttt ttccattctg gaagaagtga
     4741 aaaccgtcaa tatcggcaat gagatggcag ttacccttag cattggtcta ggtatgaacg
     4801 gagaaagcta ttaccggaat tacgatttcg caagaattgc cattgatatg gctcttggac
     4861 ggggcggtga ccaggcggtg atcaaggatg gagaacggat ccagtatttc ggaggcaagg
     4921 cccagcaggt agaaaagacc acccgtgtaa aggcccgtgt aaaggctcac gccctcaggg
     4981 aactgatgga aacgaaggac cggctgatga tcatgggaca ccgtttaacg gatattgatg
     5041 cctttggtgc agcagttgga atttaccgta ttgcaacggc tatggataaa aaggcacata
     5101 ttattattaa tgaggtgacg acctcggtcc gccctatgct ggaccgtttt gtgggaaatc
     5161 cggattaccc ggatgattta ttcctgaccg gagccaaggc ggcggagctg gcagatgcca
     5221 acaccctttt ggtggtggta gatgtaaacc gtcccagcat taccgatgca ccggagcttt
     5281 tgcgtcttat aaagacgatt gtggttctgg atcatcacag acaaagcagt gagatcattg
     5341 ataatgcggt tctttcatat gtagagccct atgcctcatc ctcctgcgag atggtagcag
     5401 aggtactgca atacattgca gatggaatta agatcaagtc gccggaagcg gatgccctgt
     5461 atgcgggaat cgttattgat accaataatt ttaccaatca gacaggtgtc aggacctttg
     5521 aagcggctgc ctttctgaga agaaacggag cagatgtggt ccgggtacgg aagatgttcc
     5581 gggataacct ggatgactac aaagcaaaag cggaagccat tcgggatgcg gagatttttg
     5641 agggctgctt tgccatcagc gtatgttcct cagaaggaat cggaagccct acggtcatag
     5701 gtgcccaggc agccaatgag ctgcttgaca tagccgggat caaggcatcc attgtaataa
     5761 cagattacaa tcataccgtt tatattagtg cccgctccat tgatgaagta aatgtacagg
     5821 ttatgatgga aaagctggga ggcggcgggc accgtaccat agcaggtgca cagctggcag
     5881 aggtcagcat tgaagaagcc aaaatccgcg taaaagcggt tattaaagag atgttagaga
     5941 agggagacat atcataatgg aagttgtgtt attagaagac gtaaaggcat taggcaagaa
     6001 gggacagatc gttaaggtaa acgatggata tgcaagaaat ttcattctcc cgaaaaaact
     6061 tgggattgag gcaaccgcta aaaatttaaa tgatttaaag cttcaaaagg ccaatgaagc
     6121 caggcttgcg gaagaacagc tggaggctgc taaggcgctg ggggcccagc tttcagaagg
     6181 atctgtcaca ctctccatgc gtgcgggaga gggcggaaga gcctttggtt cggtatctgg
     6241 aaaggagatc tccattgcca ttaagaacca gttgggatat gatattgata aaaagaagct
     6301 gattctttca gaacccctta agacctttgg ttcccatgag gttccggtga agcttcataa
     6361 ggatgtaact gcgaaaataa ttgttaaggt agtagaaagc taggaggcac ggatatggat
     6421 gatgccctga tcaaacgggt actccctcac agcattgagg cagagcaatc cgtcatcggt
     6481 tccatgctga tggaccggga tgcaatcatc acggcttccg agatcgttac agcaggagat
     6541 ttttaccagc accagtatgg catcatgttt gaggctatgc tggagctttt taatgagaat
     6601 ttaccggtgg atctggttac tcttcagaac cggttaaagg aaaaggatgt ccctccggag
     6661 gtttccagcc tggaatttgt cagggatatt atcactacag taccgacatc cgccaatata
     6721 aaatcttatg ctaatattgt acggaacaag gcggttctaa gacggcttat taaggctaat
     6781 gaagaaatag ccaatacctg ttacgcagga aaagaaccgt tggaaaccat tctggctgtt
     6841 acggaaaaga caatatttga tttgcttcag aaccgaaact ccggagattt cgtccccatc
     6901 cgccaggttg ccatgaacgt tctggagaag attgaagagg cctccaaaaa ccagggaacc
     6961 gtgacaggaa ttcctacagg ctttattgac ctggattata agacctctgg tttgcagcct
     7021 tccgatttta ttcttattgc tgcccggcct tccatgggaa agacagcttt cgtactgaat
     7081 ctggtagacc atattgcagt aaaaaaaggt ttgcccgcca tggtattcag ccttgagatg
     7141 tcaaaggaac agctggtaaa ccgtatgctg gccatggaat ccaatgtgga ttcccagaaa
     7201 ctcagaaccg gaaccttatc cgattccgac tgggatgctg tggtagaggg aatcggagtt
     7261 attggaaact ctaagcttat aatcgacgat actccaggaa tttccatcgg agagctgcgt
     7321 tccaaatgcc gtaagatgaa gctggaatac ggtcttagcg tagtcattat cgactacctt
     7381 cagttgatga gcggaagcgg aaaaagcggc gataaccgcc agcaggagat ttcagagatt
     7441 tccagatcct taaaaggtct tgcaagagaa ctgaacgctc ctgtaattgc cttatcccag
     7501 ttaagccgcg cctgcgaaac aagacaagac caccgcccta tgctttccga tttacgagaa
     7561 tccggagcga ttgagcagga tgctgacgta gttatgttct tgtatcgtga tgattattat
     7621 aataaggata cagatatgcc gaatattgcg gaagttatta ttgctaaaca gagaaatggc
     7681 cctatcggaa cagtaaatct ggtctggagg ccagagtata cgaagtttgc aaacatggcc
     7741 aagcaatgag cagaatagaa acagagggcc cccttgcccg ggaaaaacaa attcatttgc
     7801 ttatcccggg caagggggcc ctctgtttct atggggcgaa tgccccccat ctgggagaat
     7861 ggattctttg cgtatccatt ctcccagatg gcccagcgta ccagaaaaaa gcaaaccaat
     7921 caagagtatg ccccacctcc catcctccat ttcttttccc cattaaaaaa atttctcaat
     7981 tcccttcaaa aattttccaa ttcccattca taatcccttc gaatccagca tatgatataa
     8041 atagtaaggt tatgaaaact taacgaacca aaggagagga tatagctatg gctgagatac
     8101 attacttaat atcggatgca tcgaggaagg tcgatgtgga gtctcatgtc cttagatact
     8161 gggaggacga gctggagttg aaaattccca gaaatgagat ggggcaccgg tattacactg
     8221 aagcacacat ccgtttgttc aagcagatca aagacttaaa ggaaaaggga tatcagttaa
     8281 aagccattaa gactgcgctt gataaggtga ttgaggacgg cagggatcct gtcataccag
     8341 atgaattatt agagggacag gtagctcagg aattaaagga cagtgcaata tctggtacag
     8401 aggacggggc aggcctggag gtacataaca cggcaccgat ttccattgca caggaaaaga
     8461 tggagcagtt tcaggagatc atgaaccata tcattggacg tgccttagaa gtgaataatg
     8521 agcagttaag ccaggatgta agcagtctgg tcaatgacaa ggtcattaag gaaatggaat
     8581 atttaatgaa tttaaaagaa gaaaaggaag aggagcggtt taagcagttg gacgagctta
     8641 tgcgttcgta tcaaaaagat aacaaagggc gtgcggaagc ggctgcttcc agaatcccgt
     8701 tttttaaccg taaaaagaag tttgggcgaa atggaaaaaa gttatagaac cacactactt
     8761 tcagataatc agggctgtca agcaggctca ggcaaggaaa tccgcagttg ccgctggaag
     8821 tgggagctgc ggatttttta tcaaacaagt cactctttac aagcatttac aaacgtctga
     8881 aacagtcgaa acgcttcttc attcttttcc cacaaatatt ccggatgcca ttggaccccg
     8941 atgaaaaagg gatagcctgg catttccacg gcctcaatca agtgatccgg agaataagca
     9001 gatgcaatca gtccctcagc cacatccttg actgcctgat gatgcatgct gttgaccttt
     9061 atcgaggagc tccctgatat ctgggcaaga aggctgccct ttgttaaaga gaccgtatgg
     9121 catggcatgt cgtaatgaaa gggctgggta tgggcaagag gaaattcccg tgtcacctgg
     9181 gaggggatat cctgccagat gtttcctcct aaagcgatat ttaaaacctg gatcccccgg
     9241 cagattccaa gtacaggctt cttaagttcc atgatcatag gaagcagggt gatctccatc
     9301 tgatccctgg caggagatac attgccgcag tgtgcctgtg tttcttctcc aaaaagaaag
     9361 gggtgaacat cgggaccgcc tgtgaacaaa aacccatcca gatcctggga aagctgcttt
     9421 aaatcttctt ctgaggcatc taagggcatt acgaccggga ttgctcccgc tgcttttaat
     9481 gcccgtacgt aagtaggacg tgtcttaata tccccgttct ccgtatcatg ggcgggggtc
     9541 aggccaatca gtggtttttt catattagaa atgtcctttc ctggttaaag gttgaaagaa
     9601 gcctatcctt ccacctttag gttacgaatc aacgggatat gcctgcatat ccgtttgatt
     9661 tattcgtatg caggtataga gaacgtgatg atagaacaaa atgcctcttc cttagggaag
     9721 aggcatttat gtatccataa ttatgcttca gaaatagctc ctgttggaca gacaccttcg
     9781 caagcaccac aatcgataca ggtatcagca tcaataacaa actgagaatc accctggcta
     9841 atagcgctta ctgggcactc agcttcacag cttccgcagc taacgcaagc gtcactaata
     9901 acacgtgcca tgacaaatta cctccttata atttatagat ttttctatat tttatactat
     9961 taataggaaa tattcaagta gtaaatgata caattcttgt ttaaaattgg gagcaatacc
    10021 ggtcgggaac tcctgtgcgg acatccctga ttccgcttaa gatgatcttc ttggcagcga
    10081 tagctccttc ttttgacatt ggaggagtat cctttaaggg atagtccatg ccaaggcttt
    10141 catatttcac ctttcccatg tcgtgatagg gcaggacatc cagggccttt acattcttaa
    10201 gctctccgat aaagcgccca agcctgtata aatcaggggt ctggtctgtg atctggggca
    10261 ccaccacatg gcggatccat accgggattt ctttctggct taaataccgg gcaaagtcca
    10321 gaatgttttc attggactga ccggttagga ctttatgctt tgggtcatcc atatgcttga
    10381 tgtccagcat gacaagatcc gtatgttcca gaagccggtc tattttattc agataatccg
    10441 gaccattcct gtggaacatg acgcctgaag tatccagaca ggtatggatg tctttctttt
    10501 ttgcagcttc aaaaagctcg gtcacaaaat caagctgcat aaggggttcc ccaccggtgg
    10561 ccgttatgcc gccgccccgg tagaaattcc gggacgactc aaactgcttt aacagttcct
    10621 ccgcagtcat tggcgtgcct cctgccattt tccaggtgtc tggattgtgg cagtactggc
    10681 agcgcatggg gcagccctgc aaaaaaatca ccatacgtac gcctggcccg tcaacagtgc
    10741 cgaagctttc aatggaatgg atatatcctg tcatatagat cgccttcttt gctgttatta
    10801 catattgtta tggaatgtac gggatattac ttcatcctgc tgttcctttg tcaatttgat
    10861 aaaattcacc gcatatccgg atacccgtac ggtaagctgg gggtaattct ccggatgctt
    10921 ctgggcatct attagagtat cgcgggtgaa tacattgaca tttaggtggt gtccgccttc
    10981 ctccacatag ccatccaata aatttacaag gttattgatt tgggattcgc tgatatttgc
    11041 cataatataa acctcctttt gtgcttaagt gctaaaaagt gtcttccata aacagccggt
    11101 tgctttccgg atcttcctct tccgtgtcca ttgcctcaaa cagggtgggg actctgcagg
    11161 cagaatttcc gtctgagcaa tccgtggaat tcatggtggt tactgatttt gccattgttt
    11221 tatccgtact tacaataccg tcttccgata cccggatgtt catgtgaccc ccgttaccgg
    11281 ccataaactg atccagcatg gatacgatat cctcaatttg cttttccttt gggtctgcca
    11341 taacagccac tccttattaa aataccgccg gatgatgcgg tcatgattgg gtagttcttt
    11401 taaacctgat cttcgttaag agccagctct aaatccacct ctaagtctcc tgtaaagatc
    11461 tggtcttctt ttcctaaggc acctggaacg atggagaagg tattggagat accatcctgg
    11521 gcatccctga aaggaagctt tgccaccgaa gccagggaag caaccgcacc atgggtgtcc
    11581 cggtgatgca tggggtttgc acctggtgca aatgcttctc cttttttacg tccgtcagga
    11641 gttgctcccg tatttttacc ataaaccaca ttggaggtaa ttgtcaagat ggaggtggta
    11701 gggattcctc cgcggtaggt gtggttccct tttacataat tcatgaaggt gtgaaccagt
    11761 tcatttgcaa tctggtctac ccggtcatca ttattgccgt attttgggaa atccccctcc
    11821 acgatgtaat cggtcacgat tccgttttca tcccgaacgg tttttacctt ggcatacttg
    11881 atggctgata aagaatcggc aactacggat agtcctgcga ttccggtggc gaaccagcgg
    11941 atcacctttt tatcgtgaag tgccatctga atgcgctcat agctgtattt gtcatgcata
    12001 tagtggataa tgttcaatgt gtttacataa acccttgcaa gccacttcat catgtcctta
    12061 taggcgtcca tcacttcctc ataattcagg tattcagagg tgatggggcg gtatttgggg
    12121 cctacctgct ttttggtgac ctcgtcaatg ccaccgttaa tggcgtataa cagacatttt
    12181 gccagattgg cccttgcgcc aaagaactgc atttcctttc ccaccctcat ggaagatacg
    12241 cagcaggcga tggcataatc atctccgtgg gttactctca ttaagtcatc gttttcatat
    12301 tgaatggaag aagactcaat ggaggttttg gcgcagaatc gtttaaagtt tgccggcagc
    12361 tttgtggacc agagaacagt caggtttggt tccggagcag ttcccaggtt tttaagggta
    12421 tgaaggtagc ggaaggaggt ttttgtcacc agatggcgtc cgtcaatacc aactcctccg
    12481 atggattctg tcacccaggt aggatcgccg gagaacagct cattgtattc tggtgtgcgg
    12541 gcgaatttga ccaggcggag cttcatgata aagtggtcca cgaactcctg gatgtcttcc
    12601 tcagtaaagg tcccttcctc taaatctctt tgtgcgtaaa catctatgaa ggtggaggtg
    12661 cggcccaggg acatggcagc tccgttctgc tccttaaccg cggcaagata ggcgaaatac
    12721 atccactgga tggcttcctt tgcattggca gccggtttgg aaagatcaaa gccatagagg
    12781 cttcccagtt ttttcagttc cttaagggca cggatctgtt cagaaagctc ctccctttcc
    12841 cggattacat cagagtacat gatggtgcgg gtggttgcct tctgctcctc cttgtcctca
    12901 atcaggcggt cgatgccgta aagggccact cggcggtaat ctccgatgat tcgtccacgg
    12961 ccataagcgt cgggaaggcc tgtgatgatg tggttggaac ggcagtcccg catttcctgg
    13021 gtataagcgt caaaaacacc ggcattgtgt gtctttctgt gaatcgtaaa aaattccctg
    13081 acttcaggat caatggtgta gccattatcc gcacaggctt tttccgccat gcggatgccg
    13141 ccgtaaggct gcaaggaacg cttaaatggc ttatcggtct gaaaacctac aatagtctct
    13201 ttgtctttat ttaaatatcc cgggccgtgg gatacgatgg tggaaatgat ctttgtatcc
    13261 atatccagca cgcctccggc ttcccgttcc tgtcgggata agtccatgac ctgcgcccaa
    13321 agttcgtttg tcgctgtggt cggcccggcc aggaaagaat catcgccgtc ataaggagtg
    13381 taatttttct gtataaagtc cctgacgttg atttcccgtt cccaaacacc gcccgtgaaa
    13441 gctctccatt ctgttctcat agtattgtac ctccgtaata tcttcatgta taagcgtgaa
    13501 ttataaatga gtgccggcaa agattataat tcctacaatc tttgtatgaa tacattatat
    13561 atgaatactg tatacaatgt caagatgcat tcatgagaaa aattcattta taagacgccg
    13621 gaacgaaaaa aaggaattta gttcttgcta atcacatgga aaagtattat attagaaaga
    13681 cagtaagtac aatttttaag gaggaacaca agatgcagat ccagaaggat atgttaatag
    13741 gcgcactgct tgagatggac gagaacattg cacctatgtt aatgcgcgca ggtatgcatt
    13801 gcctcggctg cccggcatct cagggtgagt ccctggagga agcctgccag gttcatggaa
    13861 tagactgtga tgttctggtt tcccagatta acgaagtgtt ggcagacaga tagaatatgt
    13921 tacaggaggc agtccttaag gaccagcctc ctgttttttt gggggcaacg agccgggcgg
    13981 acatggctgc aggttcctct gcgactgcag cgatagccat aagaaatcgg ggagcgggtt
    14041 tcttatggct gccgcttatc ctctctgtaa tgcatggggc tgacgccgaa ttcctgcttg
    14101 aagatttttg aaaaggttag atcaattaac ggtacatttt catgtaatcg ccgtgggctt
    14161 ctatgagttc gtccaccatg gaacggatat cctttaaact aagctcggca gcagtatgtg
    14221 gatccagcat ggcagcctgg tatatggttt ttctgtctct ggtatgggct gcttctatgg
    14281 tgagaagctg gggattgatg ttggtcatat tcatggctgc cagctgggta gggatacggc
    14341 ctacatggca gggggtgatc ccgcttccat caacaagaca ggggacttcc acacaggcat
    14401 cggcaggaag attatggatc agaccttggt ttaatacact tgcgccgatc ttgtatggct
    14461 tgttggtcag gatggcttcc ataatgtagg aggcgtattc acgggagcgg gtatgggtga
    14521 tctccccatg atttaatata gagttttttt ccgcttccca ttcgttgatc tgcttgatgc
    14581 agcgtctggg atactcatcc agagggatct ggaattcatc gatcatatcc ggatatccgg
    14641 attttataaa caatggattg tattccgcat tatgttcact ggattccgta caataatagc
    14701 ccaaatggct gatgtactcc aaacggacca tatctttatg cttttccatc tgatttttct
    14761 caagggcctt ctggcggatc atagggtaga ggtcattacc cgccttgtca tgaagcttta
    14821 agagccaggc catatggttg attcctgcaa tcagctcggt cctaccctcc agcttatcct
    14881 ccatgtcaag ctcctttaat agagtttctg agcatacctg aacgctgtgg cataagccaa
    14941 tggttttaat ggacgtatag cgctgcatgt agccggttaa gattgccatg ggattggtat
    15001 aatttaagaa atatgcatca ggacaaactt cttccatgtc tctggcaaaa tcctccataa
    15061 caggaatggt ccttaatccc ctcatgatgc cgccgatccc aagggtatcc gcgatggtct
    15121 gccttaagcc atacttttta gggatctcaa agtcaatgat ggtacaggga tcatatccgc
    15181 ctacctggat ggcgttcacg acaaaggtgg cgccggacag tgcctttttc cggttttcca
    15241 ctcccagata agtttttatg tcagcccgcc cctgattcac atttttgttg attgcattaa
    15301 gaatcagctc tgaatcagca agccggaccg ggtcaatgtc gtatagggcg atctgagcat
    15361 cagaaagtac cggtgtgcac atgcagtcgc ccagtacatt tctggcaaat atcgtgcttc
    15421 cagcgcccat aaaagttatt tttaccatgt ttcttcctcc ttgttttcct tgtctgtctt
    15481 atgaggatat tgtataattg cagcaggaaa aaagatagga tgtttgtttc atgaatttgt
    15541 cgttttgttg tatggaggga gtattatgaa tcaatcggca agaggattga ccatttatta
    15601 ctgcggccgt gagcagtgtg catccgggca ttttttcgga cctgcaatcc ggaaacatta
    15661 tctgatgcat gtggtacttg gggggaaagg cctctaccgg gcagggggca tggaatatgc
    15721 gttaaaggaa ggagatgcat ttttaataaa gccccaggag gttacttatt atcaggcgga
    15781 taaggacgag ccatgggaat atgcctgggc ggcttttgcc ggcacggaag cagagcggct
    15841 tttatccgat taccgccagg atgaaaacgg gtatgtatac catttttctc acggagagga
    15901 atggcgtact tctatcgttc agctggcaga tgccttccag agggggggac acaatatgga
    15961 tgaaatggcg ggataccttt atctattgtt ttcccggttt cccatgcagg acagggaagg
    16021 gggagaatac gaaaaaagct atttgtcccg tgcagagggg tatatccgcc ataattacag
    16081 ttaccccatt cagatcggag atgttgcaaa ctatgtgggc attgaccgga cctatttgta
    16141 caggcttttt atgaaataca aaagcatctc ccccaagcag tatctgacgg cctaccggat
    16201 catggaggca aagcgtttgc tggaggaaac agggctgagt atcacggaag ccggtttatc
    16261 ctgcggtttt catgatgctt cggtattctg caaaagtttt ctaaagaccg agggggaatc
    16321 ccctctccag tatcggaaaa agatacggaa agagattcgg taaatataac aaaataccat
    16381 gtacctaccg ggacaattat caggtcctga atccggtcaa tgccggttgg ctcaggctga
    16441 ggctccaggg cttttgtgag gatattaaac aggaataaga aaaatagtcc ggtcaggcat
    16501 tgactggact attttaatgt aataaattac attatctttc aggaaccttt catttttatt
    16561 gaaaaaaatt ttacagcatg ttataattcc taaaaataat gcattattcc tcaaaaactg
    16621 agcatagggg atgattaaat gaaggattat aatgtgcact taacactgat tgacagaatt
    16681 atcttggatt cctataagat catgatggaa gggctggcgg attacctggg ggaggctatg
    16741 agatggtact tcacagtctg gaagatacgg aacattccgt cattaagatc attaacggac
    16801 accacacagg acgtacggaa ggaatgccga ttacggacct ggctcttcag atgctggaag
    16861 aaattgaaaa agatggtgaa aagagctaca tttcctattt taccaagaac aaaaaagaag
    16921 agccattaaa atcctccacc attgtggtac ggggggagga acgaaggatc atcggacttt
    16981 tatgtatcaa tttttatttg aatacaggtt ttgcccagat cctgaacagc tatattcctc
    17041 aaatatccac tcattccctg gttaaaactg aaacttttgc aaataatctg gatgaactga
    17101 ttttcggcaa agtccaagag gttcggaatg cggtaatgga agatgacggg atacttccgt
    17161 ctcttaaaaa taaggaaatt attaattccc tgcaccaaca gggggttttt accctgaaag
    17221 atgcggtggt aaaggtagct gattatctgg ggatttctaa aaataccgta tatatgcaca
    17281 ttcggaatgc gggagtaaat acagaaaaga agaatgaata aacattaata cagtagaact
    17341 tgttggctaa gaaaaatcct gcagcttttt gtgcaatatt acaaagaaac tgcgggattt
    17401 ttgtttgact attagaaaaa tataatgaca ttgcattctg tattacttta tgataaaata
    17461 aattacatca aataaattat ttagataaaa tttatttcat tcaacgaaag gaaggtattg
    17521 atatggagga aagtaaaaag agtaagaaag gactgggatt ggtaccaaga ctgattattg
    17581 caattatcat tggtattttg attggaaagt actgtcccag ctttgtaact tcaatattga
    17641 ttaccgcatc ggatttgttt aaacagtttt taatgtttat catccctctt atggtcgtag
    17701 cttttgttac catgggaatt gcggacttat ctcagggagc cggaaagctg ctggcattta
    17761 ccgcagcggt ttcctatgca tccacacttt tggcaggaag tgctgcttat gcagttgcca
    17821 gtacgttctt tccgtctttt gtaaatgaag aggtagttgc aaaggttgca tctgcaagtg
    17881 ataaggccat cagcggatat ttttctctga ccatcacacc gctccttgaa acgactgcag
    17941 cggttgcgct ggcctttgtt ctgggcgtat gcatcagcac catgcggggc aaagagatcg
    18001 gagatgccct gtacaatgtg atcaaagagt ttgccgaaat tattacaaag gtgctgggac
    18061 gtgtgattat tccgcttctt cctttgtata tctgcggaac gtttgccaag atgacctatc
    18121 agggtactac ttttgcgatt atgtccgtgc tttggaaggt atttctgatt gttatactgc
    18181 ttcatttaat ctatctgctt gctgcttttg gtcttgcagg tatattgacc aaacggaatc
    18241 cagtcaccat gctgaagaac caggtgcccg gctacttaac tgcaatcggc acccagtctt
    18301 ccgcagctac cattccggtt aatatcaaat gtgcggaaag caatggcatt tcagaagaaa
    18361 tccgtaattt cgttattccg ctgtgcgcga acattcatat ggccggttct atgatcacca
    18421 ttacctgctg tgtgactgca acccttctta tttacggtat gtctcatggc ttccttaccc
    18481 tgtttccgtt tatctgtgta ttgggaatcg ccctggttgc gtctccggga gctccgggtg
    18541 gctccatctt tacggcgact cctttcttcc cgattgtagg gataccggca gtaggagata
    18601 ttgccagcct tcttcaggca atgtatatag cccaggacag ctttggaacc gcttgcaacg
    18661 tatcgggaga taatgccatc agtgcactgg ttgatatgta ctaccacaaa tatattaaaa
    18721 aggacaatct aggttaaggt gactgggaaa ggagaagacc gtctatgccg tctatcagta
    18781 tttttgatgt aatcggtccc aatatggtgg ggccatccag ttcccatacc gcgggtgctg
    18841 tggcaatagc tcttctggtt aaaaaaatgt tcaacgggcc gatcaaaaag gtagaatttg
    18901 tattgtatgg ctcttttgca aaaacctata aaggtcatgg taccgaccgg gcgcttcttg
    18961 gcggcatcct gggttttgag acttatgact taagaataaa aaattccttt cagctggcgg
    19021 atgaatgcgg actgatgtat tccttctgcg tggatgaaaa agaaacagag gtacatccaa
    19081 atacggtcga gatccatgtg actggagaaa atgctggtac catgtcggtc cgcggcgttt
    19141 cattaggtgg cggtaaagtg aaaatcatca ggatcaacgg cattgatgta gactttacgg
    19201 gagaatattc cacactggtc atccgccact tggactatcc gggcatggta gcctatattg
    19261 ccaccagttt aagtgagcga aatgtcaata tcgcgttcat gcgtttgttc cgggaacgga
    19321 aaggggcgac cgcttactca gtggtagaat ctgatgagga gattccccag gaattgctgg
    19381 aaaagctgcg ggaacatccg aaagtagaag atgttatgct tattcaggtc taggaggctt
    19441 ttatggattt tatatcagga aatgaattgc tgaaattatg tgaggaaaat caatgccgga
    19501 tctcagaagt gatgagggaa cgtgaagcca gtgagttcgg cgccagttcc caagagacca
    19561 tcagccggat gaaggaagct taccggatta tgaaagaatc ctgccataag cctttagatg
    19621 aacctgtggt atccattggc ggactgatcg ggggtgaatc tgcaaaggta cgggacagaa
    19681 ggagatcagg aaaatccata tgcggaagca tgctgtccaa ggcgattacc tattcgctgg
    19741 ctgttttgga ggtgaatgct tccatgggac tgattgtggc ggcgcctacg gccggaagct
    19801 ccggagtgct gcccgggctg ctccttgccc tggaagaaga attttccctg ggtagtgacc
    19861 agatcataga tggtcttttt acggcaagtg cggttggtta tctgtttatg aggaatgcta
    19921 ccgttgccgg agcgcaggcc ggatgtcagg cagaagtcgg tgctgcttcc gcaatggcag
    19981 cggcagctgc gacggaaatt atgggcggaa cgccgcagca gtgcatggac gcagcttctt
    20041 ctgccttggt aaatctttta ggtctggtct gcgacccggt agccggcctg gtggaatatc
    20101 cctgccagaa ccgcaatgtt ttaggtgctg ccaatgcact ggtatgtgca gaaatggcat
    20161 tatcaggagt caaacagttt ataccctttg accagatgct ggacaccatg atggcggtgg
    20221 ggcggtctat tccgtttgaa ttaagggaaa cttcccttgg cggctgtgcg attactgaag
    20281 ctgcctgcgg aagggcctgt gagatatttc aatcaaagta aattaattgt gaaaggcagc
    20341 gccggtttat ggaaaccggt gctgcttttc attgtttgaa aaaaatagtt gcgagtgcaa
    20401 ccattttgtg atatgctgat tatcacccga aaaagtgtaa ttcgaccata cggcttggag
    20461 gtaaaacgca tgaacgagca cagggaaatc gggaagtata tctcgattct ccaaagactg
    20521 aacaatatgt actttgcaaa tcaattatcc ttttatcaga taggctgtgg acaacagttt
    20581 tttttattgc agatttataa aaatccgggc atgagccttc atgagctggc ttcttttggc
    20641 cattacgata aagcgactgc caccagggcg gtgaagaagc tggaagaaga ggggtatgtt
    20701 ctgactgaga tggcaaaaga ggacaagcgc cttcgaagaa tttacgttac ggataaggcg
    20761 gcggctgttg tggagaagac attggagagt gtggctgaat gggcggatat tatattgaag
    20821 ggatttacca aggaggaacg tgatgcagcg gagcaaatgc tcatccgcat ggcatacaat
    20881 gccagccatc acattatgga acagaaagga aaggaataga accttatatg gaacaaaaca
    20941 agatgaaaca gggggagaat cccctgggat ataagccagt gggacatttg ctgctgcagt
    21001 ttgcacttcc ggcaattatc gccatgctgg taaattcgat ttacaacatt gttgaccaga
    21061 tttttatcgg acaggggatc ggatatctgg gaaatgcggc taccaccatt gcattcccca
    21121 tcgtcaccat cattttggcc atatccaccc tgctgggagc cggcggaagc gcctatgcgg
    21181 ccattaagct gggggaaaag aatgagaagg aggcggacaa gacccttgga accgtattcg
    21241 cggtgaccct ggcagccagt gttgtggtta tggcagtggc ttttccgctt atgaccccca
    21301 tgttaaaggt ctttggagcc acggaaaata ccatgggata tgccaggcag tacacttccg
    21361 tcatactgat gggcactccc tttaacatgc tttctgtggt cttaagcaat atggccagaa
    21421 ccgacgggaa tccgtcctta tccatgtacg ccattttggt gggtgctgtt ttaaatacca
    21481 ttcttgatcc tgtttatatc tttgtatttc actggggtgt gaccggggca gccattgcca
    21541 ccatcacctc tcagatcatt tccgcagtgg tgctggtgca ttattttata tttaaaggaa
    21601 aacatatgcg ccttcataga aaaggattat ccattgatgg gaagatctgc cgtttggcac
    21661 tgccacttgg aatatccagc ggtatcaccc aggtagcttc tactatatta caggttgtca
    21721 tgaacaattc tctggtgtac tatggaaacc agactgatat tggcggcgat gtggccttaa
    21781 gtgccatggg cgttgtaaat aaaataggta tgatccttat ttccatctgc attgggatcg
    21841 gtattggatc tcagcccata ctagggttta acaagggggc aaaccagcca aaacgtatga
    21901 gaaggacatt tcttttggcg gccggggcgg caacagcagt ttcaattaca ggctggcttg
    21961 cctgtcagat attcccggga cagattctta gtttatttgg gactaaggat gtattgttta
    22021 cccagtttgc catccgctgt ttaaagattt atatgctggg aatcttttct gcaggcttcc
    22081 aggttgtgac caccagctat ttccagtcca cgggacagcc cctaaaggct tccgttttgt
    22141 ccatgctgcg ccagctattg ttattgattc ctctgattct tactcttcct ttgacctttg
    22201 gtctggaagg aatcctgtat gcagggcctg cggcggatat cacctcaatg atcattgtca
    22261 gccagtttgt attgtatgaa atgagaaaat taaaccgttt ttgcaaagat acataatttg
    22321 aatgatacag cagggctaag gccaggctgt atcctgtaaa tacagggaaa ggagaaatgg
    22381 aaaccatgag catgaaaacg gagatggcaa ggattttcgc cggacttaat aaatcggaca
    22441 gaaaaatggc tcttgaactg gagcaccccg ccaggggaac agcagctttg gaccaggaac
    22501 gatttacaaa aagggtgcgt gtgaaagcct ggaacgtgga tggctttcct gctttcacca
    22561 tcaatggaag ctatacgaag gcggcccatg tccttatgct tccgggcggg gcctataccc
    22621 tggagccgtc aggacgttac agagaaatgg cggagcattt tgccatagag aaacaggtga
    22681 gggtgaccat acctctatgt cctctggctc cggaatatac ggccttagat gcccaccgtt
    22741 atctggtaag ggtttacagc tttcttgctg cagagtatcc ggaggatgag tttttcttgt
    22801 ttggggactt ttccggcggc ggcctggctc tgtcattatt acaagagctg cgggacacgg
    22861 ggaacctgcc tatgccggtg agaactgccg tagtttcacc ttggctagat atcgctctca
    22921 gcaatccaaa aataaagatc gtgaaaaaat cagacccgat ccttcccgtg gaagcgctga
    22981 aagaggccgg cgttcgttac cgggggcctc tggagccgga tcatcccttt gtttctcccc
    23041 tctatgggaa ttgggatcat ctgggacaga tcctggtatt ttccgggaca gaagagatcc
    23101 ttacgccgga ttgtgagctt ttggcggaga tggcagggaa gctgcaggga acggaaatca
    23161 tatacagaaa aggggccaga atgatccatg actggatatt gatcccctgt aaagaaaccg
    23221 atgccacttt ggatttgatt tttgcatttt ttttagaaga agctttggga ttttaaaatg
    23281 aggttcggtc ctgtttcagg gccgaacctc atttttaatt tgtgatgaag tactatgaac
    23341 aaaggaacgg attaaagttt tgcaagagat tgaagggcat ggccttcaat cagcacctcg
    23401 taatgttcct tgtagtacgc ttcagaggcg tagtcctgat gaatcttgga accatactct
//
