LOCUS       c00011_NZ_CYZX..       15871 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CYZX01000011.1 Clostridium disporicum strain 2789STDY5834856,
            whole genome shotgun sequence.
ACCESSION   NZ_CYZX01000011
VERSION     NZ_CYZX01000011
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:29:23
            Original ID  :: NZ_CYZX01000011.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 126403
            Orig. end    :: 142274
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15871
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[136403:140669](-)"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(10001..14266)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..15871
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15871
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             402..935
                     /locus_tag="ctg11_134"
                     /transl_table=11
                     /translation="MYENSAELAENKLLVLYVIKSLKHPISNTQLTEIILENNFINYFT
                     LQQYITELLSSEFLKYIEKNDKKLLTITTKGEKVLSFFTQRISPIKRDIIDNYISSVID
                     NIKKELTIYSDYTIENSDSFIVNLKALEDEMLLIDLKVSVPTKSQAKALCSKWKDNPSD
                     IYTRIMQSLFSDED"
     CDS             complement(932..1807)
                     /locus_tag="ctg11_135"
                     /transl_table=11
                     /translation="VNSILVCNTGADSLSRIILNDLHLEKITFNLGEKPIGPNGIEVYD
                     DGFITTNSYSDSISFFDKKYLKEIKNAKIGPSPNDLIVYKKKVYTICGESNSVVVYDIL
                     EDKALYEIATGSWPYSVEADIEKGIAFIANFESNDITVINMDNNNVIKKIDANEYPTKV
                     LLSKDKEFLYVCESYLGHDKSGFLDVISAKTLKSIKRITVGSSPMDVIEGEENIYVSNF
                     TDGTISVINKGNMILQESIYVGGMPKGMITHENKIFVSDYLKGKIYVIENNKINKVIAI
                     ESEPNAMTLF"
     CDS             1976..2221
                     /locus_tag="ctg11_136"
                     /transl_table=11
                     /translation="MYIYKTSGVCSTEIHIDVKDDKIENVNFVRGCAGNLLGISSLVKG
                     MNVNDAIDKLQGIQCGSKGTSCPDQLAKALLSMKNA"
     CDS             complement(2263..2880)
                     /locus_tag="ctg11_137"
                     /transl_table=11
                     /translation="MKNGLKYITYIIVIACIIFLFKPKILKAVGWSYKDIYNVNIKTEE
                     IESMYKDLDIQYLRYEWAEELDIDNEPTILVYHHTAIKNISPEDIDKLHKNKGWKGIGY
                     HYYIRKDGTIYKGREDEAEGSHVKGYNKKSIGVCLEGNFEEEYLTDEQIEALKKLSIYI
                     CLKYNIKDILPHKELGNTLCPGKNFPLEEIKNDIIKELKSIK"
     CDS             complement(3048..3758)
                     /locus_tag="ctg11_138"
                     /transl_table=11
                     /translation="MSKHLHIMAKEGSIAETVLLPGDPLRAKFIAENFLEDVVCYNEVR
                     GMYGYTGTYKGKRVSVQGTGMGLPSHSIYVNELIQFYGAKRLIRIGSAGSCNDNVNVRD
                     IVLAQSASTNSGINKRRFNGLDYAPSANFQLLYEAYNIAKAKNANVKVGNVLSSDLFYD
                     DTNHFSLKTWAEYGVLAVEMETAELYTLAAKYGVEALSILTISDHIFKGEETSPEERQN
                     TFTDMMEIALELIK"
     CDS             complement(3832..5142)
                     /locus_tag="ctg11_139"
                     /transl_table=11
                     /translation="MNYNEAMKYITEVGNFGSNYGLERTFRLLELLGNPQDNLKLIHVA
                     GTNGKGSTTAMITKMLNGLGYKVGMYTSPFLEEFEERIQINGENIPKDVLAELVTYIKP
                     YIDKVEEEGYGHPTEFEMITVLMLLYFEREKIDFGVVEVGLGGRLDSTNVIIPIVSVIT
                     SISFDHTNLLGNNLREIAGEKCGIIKRNIPTIVFPQQEEVMDVVIKKCEKENSKLYIVN
                     FNDAELLDIVKGDKPFQKVKIKGEKEYILELPLLGEHQIYNLALAIKVMEVVEKQGFIH
                     LNNKAIENSVREVMWKGRLEVLSNNPLIVIDGAHNIQGITTLKNNIQKYFNYKDVYLIL
                     GILADKDVEMMVKEITPLAKKVYAVTPHSIRAELAQDLRDEIIKYNENCKAYEDYEEAF
                     NNALKDAKENDLIIASGSLYMIGDMRKLITRNYINKK"
     CDS             complement(5291..5506)
                     /locus_tag="ctg11_140"
                     /transl_table=11
                     /translation="MAQRITDTIKDSSGEITHYILDSGEKLEKADGVNRAKNGEIEGVI
                     IAHSRKGEEYLRTKPDGNEGNNLSSL"
     CDS             complement(5550..6869)
                     /locus_tag="ctg11_141"
                     /transl_table=11
                     /translation="MDLVKDDVKKLFLKYFFPTVGAALVTSIYILFDTIFIGQGVGGDG
                     LAALNIVLPIYSLVFGVGYLIGVGGSTVLGIERGRGHNDKAIDIFSLSVYISIASAALF
                     LVVGKFFMDDIALMLGATDITISLIEEYMKIVALGFVPFTIGSTLQGFVRIDKNPKLAM
                     IATITGGLINIILDYIFVFPLNMGMYGAGLATVLSYTISMGILLTHFLSKKNTLRLNYR
                     CFRYKYLSRIISNGIPSFFIEMSTGVIIYLFNFQLLKFIGETGVTAYSIISNTAIIFIS
                     ISNGICQTIQPIVSVNIGAKKYKRSMEFRKIAFYVAIIFGLTATILGFLFPEELIKVFV
                     TPTEEIKQIAVVAIRMYFTAFIIMGANMVLAGYFQAIEMPKVAIIISSLRGLIVVGILI
                     FVLPCFLGVSGIWLSVPITELITFIVAIYISNRTFKEKYV"
     CDS             complement(6927..9569)
                     /locus_tag="ctg11_142"
                     /transl_table=11
                     /translation="MEEKKNLSTTYNPKEFEERIYKTWEEKKYFTPVVDKTKKPFTIMM
                     PPPNITGKLHLGHALDNTMQDMLIRFKRMQGYCTLWLPGTDHASIATEVKVENELLKEG
                     KVKKEMGREAFLEEVWKWAEEYKGTIRGQLKKLGVSCDFTREAFTMDENLNKAVRTVFV
                     KLYNDGLIYQGNRITNWCPKCTTALSDAEIVYEEKEGSFWHINYPLSDGSGYLEIATTR
                     PETLLGDTAVAVNPNDERFKHLIGKTLKLPLTDREIPIIGDDYVDIEFGTGAVKITPAH
                     DPNDFQVGQRHNLPQIRVMDDHGVINELGGKYQGLDRYEARKQMIKDLDEQGLLVKIKP
                     HTHNVGTHDRCGTVVEPIISQQWYVKMESLAKPAIEVVKEGKTKIVPERFEKIYFNWME
                     NIQDWCISRQLWWGHRIPVFYCNDCGHMMVEVDAPTKCSKCSSENLRQDEDVLDTWFSS
                     ALWPFSTLGWPEKTPDLDYFYPGNVLVTGYDIIFFWVARMIFSGLYNMDKTPFDTVLMH
                     GIIRDANGIKMSKSLGNGVDPLEVIEEFGADALRFMLVTGSSPGNDIRYIPEKVESARN
                     FANKIWNASRFVMMNLDTELMNKYADCTEYSLADKWILSRMNTVVKEVTENLEKYELGI
                     ANQKVYDFMWTEFCDWYIELVKPVFFSDNEKAKGVAYNVLYTVLTTGLQLLHPAMPYIT
                     EEIYTTLTNGESIAISNWPECNESLVDAKAVKDMDYIIESIKGLRNLRAEMNVPPSRKA
                     KVICYISNEAKDAFTAGIPYIEKLGSASEVEFIADKALVPENAVSLVVKGGELFMPLLD
                     LVDKDKELERLGKEKTKLEGEITRIEKKLSNQGFVAKAPEAVVEGEKAKMAKYQEMLDA
                     VLVRIEAFK"
     CDS             complement(10001..14266)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_143"
                     /sec_met_domain="HGD-D (E-value: 2.4e-53, bitscore: 175.2,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 1.2e-34, bitscore:
                     113.2, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYRIGIDVGSTTVKLVVLDNKNEIIYSKYQRHFSDIRISIVDLVK
                     NAYEALGNIDCSIVVTGSGGLSVSKWLNLDFIQEVIACSKTVEVMIPETDVVIELGGED
                     AKITYFNGGLEQRMNGSCAGGTGAFIDQMAVLLNTDAQGLNEYAKSFKVIYPIASRCGV
                     FAKTDIQPLINQGAHKEDIAASIFQAVVNQTISGLACGKPIRGNVAFLGGPLNFLSELR
                     NRFVETLRLTKEQTITPENAELFVAIGAALLSDENKQVSLKDLVESFKGILAIKESDVK
                     RLTPLFRDEEEYRVFKERHNKAIVKRGDLLSYKGKAYLGIDAGSTTTKVALINDKNELI
                     YSFYEGNDGDPLKKVIKILNDMYKIIPKDVEIVNSTVTGYGEDLIKAALHIDIGEIETM
                     AHYKAASYFLPEVNFILDIGGQDMKSMGIKNGTIDSILLNEACSSGCGSFIEGFAKSLG
                     MDVKEFAKEGLFSKAPVDLGSRCTVFMNSRVKQAQKEGAEVSDISAGLSYSVIKNALFK
                     VIKMRNENDMGDKIIVQGGTFYNDAVLRSFEIISGKEVIRPDIAGIMGAFGCAIIAKER
                     YIEGRKSSILSSEEIKKFQIETDFSRCGRCGNNCLLTINKFSNGEEFISGNRCEKALGI
                     IKNKNEEIPNLYKYKYKRIFSYKPLPIKEAKRGVIGIPRVLNIYENYPFWFTMLTNLGF
                     RVILSDASSKKIYELGIETIPSESACYPAKISHGHIMNLINRGIKTIFYPCIPYEKKEF
                     KDATNHYNCPIVTSYPEVIRTNIDELKERNVKIIEPFLSLDNYKVLAKRIVEEFKDYNI
                     SLDETKEAIKKAAVERLECKRDIEKKGEEVLEYLKVNNKKGIVLCGRPYHIDPEINHGI
                     PEIITSYGMAVLTEDSISHLGKLDDPLRVVDQWMYHSRLYRAASFISKNPYLEIIQLNS
                     FGCGLDAVTTDQVSDLIISKGKIYTALKIDEGNNLGAARIRIRSLYAAIKERERLNYKP
                     IEEKIEYKPPIFVKEMRKKHTILSPQMSPIHFDLLEKAVKECGYNVEVLPAMDVKSIDE
                     GLKYVNNDACYPSIIVVGQIINALKSGKYDVNNTSVLITQTGGGCRATNYIGFLKMALK
                     DAGFENVPVISLNALGMGEQPGFKITLKFISRAIMALVYGDLFMRVLYRTRPYEKNKGD
                     AERLYEFWNEKVKENLENGNRGIFNKNIKEIIKDFDNLELNDIKKPRVGVVGEILVKYH
                     PTANNDIVNILENEGAEAVVPDLLDFFMYCAYDSGYKAEYLGKSKISKNIGNIVISYLE
                     SYRKVMIEELAKSKRFDSPKHIAELAKLAQPILSIGNQTGEGWFLTGEMIELIKSGVNN
                     IACVQPFACLPNHVTGKGMIKILRERYPNSNIVAIDYDPGASNVNQVNRIKLMLSVAKK
                     NLECDRVSNKEIVDNILTK"
     CDS             complement(14382..14549)
                     /locus_tag="ctg11_144"
                     /transl_table=11
                     /translation="MDNNKNRMKDRSKSKNELRKIDPTGNSEVGIENGEKIGAHAHNKK
                     SYKTYEWMND"
     CDS             complement(14581..14841)
                     /locus_tag="ctg11_145"
                     /transl_table=11
                     /translation="MDKYDYVFKWLKSATKPERHIDEMEAFAKKHPIIFMKFHKDSSKI
                     VNNDINDEKYIKAKEELTKLFDENEEDFRPVFNAIKSKFNY"
     CDS             complement(14860..14991)
                     /locus_tag="ctg11_146"
                     /transl_table=11
                     /translation="MGNQMKKTKKQKKNISHNPQVESVKACFGEPKAKPYDPTDFKI"
     CDS             15204..15758
                     /locus_tag="ctg11_147"
                     /transl_table=11
                     /translation="MNNLYPISKENFKKLINIRFNNISDGLDNFSNGILECNDKLLSFT
                     EKENRFLKFFKDTLLLNSGHIIIDFYLKNLNGEEILHLLEALDHNNKIILLQELKNLKD
                     DSVYFTLDNNNLMDFITILNTRALFFCTIYLNTFPFTIWGNYDLKFPVFFSDINTLNIY
                     KNLAEKNGLSINSINIKRGCL"
ORIGIN
        1 ctttattccc ttctggataa ataatccact tgcccattac aaaaaatgtc gcttttacat
       61 tatatttatt tagtacatct aatatgtcat acagatattc attttcagcc caattaacat
      121 caaaggttaa tgccacttgc tttttatctg tattcacttt aaaaataggc ttcttatcaa
      181 gattaccatt aactaacata gattttgctc ctataataga tgtaaccata gttccaataa
      241 tcaaaaatat agctattata atctttcttt ttctaaacat atcactcctc ctttgtccat
      301 aataatttat attctttatt tataatatta atgcctatat tattccacaa ttctaaattt
      361 atgttataat aaaatagacc cttatataat ggaggtttag tatgtacgaa aattcagcag
      421 aattagcaga aaataaatta ttagttttat atgttataaa atcattaaag catccaatat
      481 caaatactca gttaactgaa ataattttag aaaataattt tattaattat tttactttac
      541 agcaatatat aactgagcta ttatcttctg agtttctaaa atatatagaa aaaaatgata
      601 aaaagctttt aacgattact actaaaggtg aaaaggtgct ttcgttcttc acgcaacgaa
      661 tttcaccaat aaaaagagat ataattgata attatatctc ctcagtaatt gataatataa
      721 aaaaggaatt aactatttat agcgattata ctatagaaaa tagcgattct tttattgtta
      781 atcttaaagc tctcgaagat gagatgctat taatcgactt gaaggtgtct gttccaacaa
      841 aatctcaagc taaagcatta tgcagcaaat ggaaagataa tccttcagat atttatacta
      901 gaattatgca aagtttattt tctgatgaag attaaaacaa agtcatggca ttgggttcag
      961 actcgattgc tatgacttta tttattttgt tattttctat aacatatatc tttcctttta
     1021 agtaatctga aacaaatatt ttattttcat gagtaatcat tcctttaggc attcctccaa
     1081 catatatact ttcttgaaga atcatgttgc ccttatttat tacgcttatt gttccatcag
     1141 taaaatttga tacatatatg ttttcctccc cctctataac atccataggg gaactaccta
     1201 cagtaattct ctttatactt tttaatgttt tagctgaaat cacatctaaa aaaccacttt
     1261 tatcatgacc taagtaactt tcacatacat acaaaaattc tttatcttta gataacaata
     1321 cctttgtagg atactcatta gcatctatct tttttataac attattatta tccatattaa
     1381 taactgtaat atcattactt tcaaaatttg ctatgaatgc tattcctttt tcaatatcag
     1441 cttctacgct ataaggccag cttcctgtag caatttcata taatgcttta tcctctagaa
     1501 tatcatatac tactactgaa tttgattccc cacaaatagt ataaactttc tttttatata
     1561 ctattaaatc attaggcgat ggtcctattt ttgcattttt tatctcttta agatattttt
     1621 tatcaaaaaa tgatattgag tcactgtaac tattagtagt tataaaccca tcatcataga
     1681 cctcgattcc attaggtcct ataggtttct cacctaaatt aaatgttatc ttttctaaat
     1741 gcaaatcatt taaaataatt cttgaaaggg aatctgctcc tgtgttacaa actaatatag
     1801 agttcaccct tatttcacct cctttaggtt gaaacctctt gtacttttaa tatatgcatc
     1861 tttataaaac ttggcacatt ttttcaatat tacataattt tattttgatt ctttcttttt
     1921 attgtataag gatttataat attattgtta ttacttatta tggggaggca tttaaatgta
     1981 tatttacaag acttctggtg tttgttcaac agaaatacat attgatgtaa aagatgataa
     2041 aattgaaaat gttaatttcg taagaggttg tgctggaaat ttacttggta tttcttcact
     2101 agttaaaggt atgaatgtta acgatgcaat tgataaatta caaggaattc aatgtggttc
     2161 taaaggaact tcttgccctg atcaattagc taaagcttta ttatcaatga aaaatgctta
     2221 atatacaaaa agagttgctt taaaacgact cttttttctt tattacttaa tacttttaag
     2281 ctcttttata atatcatttt taatttcttc taatggaaaa ttctttcctg gacaaagagt
     2341 atttcctaac tctttatgag gaagaatatc ctttatatta tattttaaac atatatatat
     2401 tgaaagcttc tttaacgctt ctatttgttc atctgttaaa tactcttctt cgaagtttcc
     2461 ctctaagcaa acacctatag atttcttatt atatcctttc acatgagatc cttcagcctc
     2521 atcctctctt cccttgtaaa tagttccatc tttccttata taataatgat atccaattcc
     2581 cttccaacct ttatttttat gtaatttatc tatatcttct ggagatatgt tctttattgc
     2641 tgtatgatga taaaccaata ttgtaggttc attatcaata tctaattctt ctgcccattc
     2701 atatcttaaa tactgtatat ctaaatcctt atacatactc tcaatttctt ctgttttaat
     2761 attaacattg tatatatctt tatagctcca tccaacagct tttaaaattt taggtttaaa
     2821 taaaaatatt atacaagcaa tcactattat atatgttata tattttaatc catttttcat
     2881 aaaaacacct cttcatatta tatctattat aattttcaca tgaagagaac cgttatattt
     2941 taaccaataa aataatcttt tctagtacaa tcacctaaat taattacttt tattttataa
     3001 tttgtaaata aaaaaagaaa agattaaaaa tcttttcctt taaaatacta ttttattaat
     3061 tctaaagcaa tttccatcat atctgtgaaa gtattttgtc tttcttctgg tgaagtttct
     3121 tctcctttaa aaatatgatc tgaaattgtt agtatagata gagcttctac tccatatttt
     3181 gcagcaagtg tataaagctc tgcagtttcc atttcaactg ctaatacacc atattctgcc
     3241 caagtcttta atgaaaaatg atttgtatca tcataaaata aatcacttga taaaacattt
     3301 cctaccttta catttgcatt ctttgctttt gctatattat aagcttcata taataattga
     3361 aaattagcac ttggtgcata atctaaacca ttaaatcttc ttttgttaat tccagaattt
     3421 gttgatgcac tttgagcaag tactatatct cttacattca cattatcgtt acaagatcca
     3481 gctgaaccta ttcttattaa tctcttagca ccataaaatt gtattaattc atttacataa
     3541 atagaatgtg aaggtaatcc cattcctgta ccttgaactg atactctttt acctttatat
     3601 gttcctgtat aaccatacat tcctctaact tcattataac aaactacatc ttctaaaaaa
     3661 ttttcagcta taaatttcgc tcttaaagga tctcctggta gcaatactgt ttctgctata
     3721 gaaccttctt tagccataat atgtaaatgt tttgacatat ttattcctcc taacaactca
     3781 tgtattatac atagtatatt acatactaat ataatagtaa atacaggctt tttatttttt
     3841 attaatataa tttctagtaa ttaattttcg catatcacca atcatataca atgatccact
     3901 tgcaattatt aaatcatttt cttttgcatc ttttaaagca ttattaaatg cttcttcata
     3961 atcttcatat gctttacaat tttcattata ctttataatt tcatctctta agtcttgagc
     4021 taattcagct cttatagagt gtggagttac agcataaacc tttttagcta atggtgtaat
     4081 ctctttaacc atcatctcta catctttatc ggctaaaata cctaaaatca aatatacatc
     4141 tttataattg aagtattttt gtatattatt ttttaaagta gttattcctt gaatattatg
     4201 tgctccatca ataactatta agggattatt acttaatact tctaatcttc ccttccacat
     4261 tacttctctt acactattct caatcgcttt attatttaaa tgtataaatc cttgtttctc
     4321 tacaacttcc ataaccttta tagccaaagc taagttatat atttgatgct ctcctaataa
     4381 aggtaattct aatatatact ctttttcgcc ttttatcttt actttttgaa atggtttatc
     4441 acctttaaca atatctaata attcggcatc attaaaatta actatatata actttgaatt
     4501 ttctttttcg catttcttaa taactacatc cataacttct tcctgttgag gaaatactat
     4561 agtaggaata tttcttttta ttattccaca tttttctcca gcaatttctc ttagattatt
     4621 tcctaataaa ttagtatgat caaagctaat agatgtaatt actgatacta tagggataat
     4681 tacattagtt gaatctaatc ttccgcctaa tccaacttca actactccaa aatctatctt
     4741 ctctctttca aaataaagaa gcattaaaac agtaatcatt tcaaattcag ttgggtgccc
     4801 atatccttcc tcttcaacct tatctatata gggcttaata taagtcacca gttccgctaa
     4861 aacatcttta ggaatatttt ctccatttat ttgaattctc tcttcaaact cttccagaaa
     4921 aggtgaagta tacataccaa ctttatatcc taatccattt agcatttttg ttatcattgc
     4981 tgtggtagac cctttaccat tagtgcctgc aacatgtatt aatttcaaat tatcttgtgg
     5041 atttcctaaa agttctaata atctaaaagt tctctctagt ccataattcg acccaaaatt
     5101 tccaacttca gttatgtatt tcattgcttc attataattc atctttttac ctctttgctt
     5161 taaaatctaa tgtatattta ctcccattat ttagacataa ttataaataa aaacttttaa
     5221 aatatcaaat tttacacaat aaaaagatac cattaaaata ttaatggtat ctatgattaa
     5281 tatctatatt ttataatgaa gataggttat ttccttcatt tccatctggc ttagttctta
     5341 ggtactcctc accttttctt gaatgagcaa ttataactcc ttcaatctcg ccattttttg
     5401 ctctattaac accatctgct ttttcaagct tttctccact atctaatata taatgagtta
     5461 tttctccact actatctttt atagtgtctg taattctttg tgccataaaa catcacctct
     5521 tagtaatatt ttaagctagt acagatattt tatacgtatt tttctttaaa agttctatta
     5581 cttatatata tagctacaat gaaagtaatt aattctgtta tcggtacact aagccatatt
     5641 ccacttactc ctaaaaaaca tggtaataca aatattaata ttcctacaac tattaaccca
     5701 cgtaatgatg aaataattat tgctactttt ggcatctcta tagcttgaaa gtatccagct
     5761 aataccatgt tcgctcccat tattataaat gctgtaaagt acattctaat ggcaacaact
     5821 gcaatttgtt ttatctcttc agttggagtt acaaatactt taatcaattc ttctgggaat
     5881 aaaaacccta aaatagtagc cgttaatcca aatataatag caacatagaa tgctatcttt
     5941 ctaaactcca tagatctttt atatttttta gctcctatat ttacactcac tataggctgt
     6001 attgtctgac aaattccatt acttatagaa ataaaaatta tagctgtgtt agatattatg
     6061 ctatatgctg ttacgccagt ctctcctata aatttcaata gttgaaaatt aaataagtat
     6121 attattactc ctgtagacat ttctataaag aaacttggaa ttccattgct aattattcta
     6181 gataaatatt tatatctaaa gcatctataa tttagtctca aagtattttt tttagataaa
     6241 aaatgtgtta acaatatccc catacttata gtatatgaaa gaactgttgc aagtcctgca
     6301 ccatacattc ccatattcag aggaaataca aatatataat ctaatataat atttattaat
     6361 ccaccagtaa ttgtagctat catagcaagc tttggattct tatctattct cacaaatcct
     6421 tgaagtgtag accctattgt aaaaggaaca aaacctaaag caactatttt catatattct
     6481 tctatcaaac taatagttat atcagtagct cctagcatta gggctatatc atccataaaa
     6541 aatttaccca caactagaaa aagtgctgct gaagctatag atatatatac tgataaacta
     6601 aatatatcta tggccttatc attatgcccc cttcctcttt ctattcctaa aacagtagaa
     6661 ccacctactc ctattaaata tccaactcca aagactaaag agtatattgg taacactata
     6721 ttcaaagctg caagtccgtc accacctact ccttgtccaa taaaaatcgt atcaaataga
     6781 atatatatag atgtaactaa tgcagctcct accgttggaa agaaatattt taaaaataat
     6841 ttttttacat catcctttac taaatccatg attcccccta attttctata taaaagactg
     6901 ccccttacga gacagtctca atactactat ttaaatgctt caattcttac taaaactgca
     6961 tcaagcattt cttgatactt agccatctta gctttttcac cttcaactac tgcttcagga
     7021 gcttttgcaa caaatccttg attagaaagt ttcttttcta ttctagttat ttcaccttct
     7081 aatttagtct tttctttgcc taatctttca agttccttat ccttatctac taagtcaaga
     7141 agtggcataa ataactctcc acctttaact actaaagata ctgcattttc tggaacaaga
     7201 gctttatcag ctataaattc tacttctgaa gctgaaccta atttttcaat atatggtata
     7261 cctgctgtga atgcgtcctt agcttcatta gaaatatagc aaataacctt agcctttctt
     7321 gatggtggta cattcatttc agctcttaag tttcttaatc ccttaataga ttctatgata
     7381 taatccatat cttttactgc ttttgcatct actaaacttt cattacattc aggccaatta
     7441 gatattgcta tagattcacc attagttaaa gtagtatata tctcttcagt tatatatggc
     7501 attgctgggt gtaataattg taaacctgta gttaatacag tatacaatac gttgtaagct
     7561 actccctttg ctttttcatt atcactaaag aatactggtt ttacaagttc tatataccaa
     7621 tcacagaatt cagtccacat gaaatcataa accttttggt ttgctatacc aagttcatat
     7681 ttttctaagt tttctgtaac ttctttaact acagtattca ttcttgaaag aatccactta
     7741 tcagctaagc tgtattctgt acaatcagca tatttattca ttaattcagt atcaaggttc
     7801 atcataacaa atcttgatgc attccaaatt ttattagcaa agtttcttgc tgattcaact
     7861 ttttctggaa tatatcttat atcatttcct ggtgaacttc ctgttactaa cataaatctt
     7921 aaagcatctg ctccaaattc ctcaattact tctagtgggt caacaccatt tcctaaagat
     7981 ttactcattt ttataccatt cgcatctctt ataataccgt gcattaacac tgtatcaaat
     8041 ggagtcttat ccatgttgta taatcctgag aatatcattc tagcaaccca gaagaatatt
     8101 atatcatagc cagtaactaa tacatttcct ggatagaagt aatctaaatc tggtgtcttt
     8161 tcaggccaac ctaatgttga gaaaggccat aatgcagatg agaaccaagt atctaataca
     8221 tcttcatctt gtcttaagtt ttctgatgaa cattttgaac atttagttgg tgcatcaact
     8281 tctaccatca tatgtccgca atcgttacag tagaatacag gtattctgtg tccccaccat
     8341 aattgtcttg aaatacacca gtcttgaata ttttccatcc agttgaagta tattttttca
     8401 aatctttctg gaacaatttt agtttttcct tctttaacaa cttctatagc tggttttgct
     8461 aaagattcca tctttacata ccattgttga gatattatcg gttcaacaac agttccacat
     8521 ctatcatgtg taccaacatt atgagtgtga ggttttatct taactaaaag tccttgctca
     8581 tctaagtctt taatcatttg ttttctagct tcatatctat ctaaaccttg atattttcca
     8641 cctaattcat taattactcc gtggtcatcc ataactctaa tttgtggtaa gttatgtctt
     8701 tgcccaactt ggaagtcgtt tggatcatgg gctggagtta tcttaactgc accagttcca
     8761 aactcaatat caacataatc atctccgatt attggaattt ctctatctgt tagaggtaat
     8821 tttaaagtct taccaataag atgtttaaat ctttcatcat ttggattaac agcaactgca
     8881 gtatctccaa gtaatgtttc tggtcttgtc gtagctattt ctaagtatcc agaaccatca
     8941 gataaaggat aatttatatg ccagaagcta ccttcttttt cttcataaac tatttctgca
     9001 tcagataaag cagttgtaca ttttggacac cagtttgtta ttctgtttcc ttgatatatt
     9061 aatccatcat tatataactt aacgaaaact gttctaacag ctttatttag attctcatcc
     9121 atagtaaatg cttctctagt aaagtcacaa gaaacaccta atttcttaag ctgtcctcta
     9181 atagttccct tatactcttc agcccatttc caaacttctt ctaagaaagc ttctcttccc
     9241 atttcctttt taactttacc ttcttttaaa agttcatttt caacctttac ttctgtagct
     9301 atagaagcat ggtctgttcc tggaagccat aatgtgcagt atccttgcat tctcttaaat
     9361 cttataagca tatcttgcat agtattgtct aatgcatgcc ctaagtgaag cttaccagtt
     9421 atatttggtg gtggcatcat tattgtgaat ggctttttag ttttatcaac gacaggagtg
     9481 aaatatttct tttcttccca tgttttatag attctttctt caaattcttt tggattatac
     9541 gttgtagata aattcttttt ctcttccata aataaaacct cctgaataag tttcttatat
     9601 atttaaagtt cttatataaa gactacttta taaagactac tttacaaaaa ttaactttac
     9661 ataaaaataa aaaagagcct tagtccaaaa aaggacgaag actcgcggta ccacctttat
     9721 tcctgagtga cactctaaat tttaatttag ataatggaac ttacatctac taaatatgaa
     9781 tagatatttc ctttttaaat ctcaggctct taatttaata acgactagat tagccgtctt
     9841 aacttactat aatttcagct aagaaactca aaagctacct tcagaatatt tcatatagaa
     9901 ggcttacagc caaggccctc ctctcttaat acttcctatt cttactcctc tttttcacag
     9961 tttttatata ttaattttac tttatactat gatatttttt ttattttgtc aatatattat
    10021 ctacaatttc tttattacta actctatcac attctaaatt tttctttgca actgataaca
    10081 ttaattttat cctattaact tgattgacgt tagatgctcc tggatcataa tctattgcta
    10141 caatattaga attcggatat cgttctctta gtatctttat catccctttt cctgtcacat
    10201 ggttaggtaa gcatgcaaaa ggttgtacac aagctatatt attaactccg ctttttataa
    10261 gctctatcat ttccccagtt aaaaaccaac cttcaccagt ctgatttcct atagataaaa
    10321 ttggctgtgc caatttagct aattcagcta tatgctttgg tgaatcaaac cttttacttt
    10381 ttgcaagttc ttctatcata acttttctgt aactctctaa atagcttata actatattcc
    10441 ctatattctt acttatttta ctctttccta gatactcagc tttatatcct gaatcatatg
    10501 cgcaatacat aaagaaatct aacaaatcgg gaacaacagc ttctgctcct tcattttcta
    10561 gaatattaac tatatcatta ttagccgttg gatgatattt tactaatatt tcacctacta
    10621 cacctactct tggcttttta atatcattta attctaaatt atcaaaatct tttattattt
    10681 cttttatatt tttattaaag atacctctat taccattttc aagattttct tttacttttt
    10741 cattccagaa ttcatacaat ctctcagcat cacctttatt tttctcataa ggtcttgttc
    10801 tgtataaaac tctcataaat aaatctccat aaactaaagc cattatagct ctacttataa
    10861 atttaagtgt tattttaaaa ccaggttgtt cacccatacc taacgcatta agtgaaatta
    10921 caggaacatt ttcaaatcct gcatctttaa gagccatctt taaaaaccca atataatttg
    10981 tagctctaca gcctccccct gtttgagtta ttaatactga agtattattt acatcatact
    11041 ttcctgactt taaagcattt atgatttgac caactactat tattgatgga taacaagcat
    11101 cattatttac atacttcaac ccttcatcaa tagatttaac atccatcgct ggtaatactt
    11161 ctacattata tccacattct ttcactgctt tttctaataa atcaaaatgt ataggcgaca
    11221 tttgaggtga taatatagta tgtttctttc tcatttcctt tacaaatata ggtggtttat
    11281 attctatttt ctcttctatc ggtttataat ttaatctttc cctttccttt atagcagcat
    11341 atagagatct aattcttatc ctagctgcac ctaaattatt tccttcatct atttttaaag
    11401 ctgtatatat ttttcctttt gaaataatca aatctgatac ctgatctgtt gttactgcat
    11461 ctaagccaca tccaaatgaa tttaattgta ttatttctaa atatggattc ttagatataa
    11521 atgatgctgc tctataaagt ctcgaatgat acatccattg atctacaact cttaaaggat
    11581 catctagttt gcccaagtga gatatactat cttctgttaa tactgccata ccataagatg
    11641 taattatttc tggtataccg tgatttattt caggatcaat atgatatggt cttccacata
    11701 aaactatccc ttttttgtta tttaccttta aatattctaa aacctcttct ccttttttct
    11761 ctatatctct tttacattct aatctctcaa ctgcagcttt ttttattgcc tccttagtct
    11821 catctaaaga tatgttataa tctttaaatt cttcaacaat tcttttagct aaaactttat
    11881 aattgtccaa agataaaaat ggttctataa tcttaacatt tctctctttt aattcatcaa
    11941 tatttgttcg tataacctct ggataagatg ttactatagg acaattataa tgattagtcg
    12001 catctttaaa ttcctttttt tcataaggaa tacaaggata gaaaatcgtc tttattcctc
    12061 tattgataag gttcattata tgtccatgac ttatcttagc aggataacaa gctgactctg
    12121 atggtatagt ttctatacct aactcatata tctttttgct agaagcatct gaaagtatta
    12181 ctctaaaccc taaatttgtt aacatagtaa accaaaatgg ataattttca taaatattta
    12241 gcactctcgg aataccaata acaccccttt tagcttcctt tattggtaat ggtttataac
    12301 taaatattct cttgtattta tacttatata gattgggaat ttcttcattt ttatttttaa
    12361 ttataccaag tgctttttca cacctattac ctgaaataaa ttcttctcca tttgaaaatt
    12421 tatttattgt tagtaaacaa ttattcccgc atctaccaca tcttgaaaaa tcagtttcta
    12481 tctgaaattt cttaatttct tcactagata gaatacttga ttttcttcct tctatatatc
    12541 tctcctttgc aattatcgca catccaaaag ctcccattat gcctgctatg tctggtctaa
    12601 taacctcttt acctgaaata atctcaaaac ttctaagcac tgcatcatta taaaaagttc
    12661 caccttgaac tattatttta tctcccatat cattttcatt tctcattttt ataactttaa
    12721 atagagcatt ttttattaca gagtaggaca atcctgctga tatatctgaa acttcagccc
    12781 cttctttttg agcttgtttt actcttgagt tcataaacac tgtacatctt gatcccaaat
    12841 caactggtgc tttcgaaaat aatccttctt ttgcaaattc tttaacatcc atgccaagag
    12901 acttagcaaa accttcaata aatgaaccac agcctgaaga gcaagcttcg tttaaaagaa
    12961 tactatctat agtcccattt tttatcccca tagatttcat atcttgtcca cctatatcta
    13021 gaataaaatt tacttccggt aagaaataac tagcagcttt atagtgagcc atagtttcaa
    13081 tttcacctat atctatatgt aaagctgctt ttattagatc ctctccataa ccagtaaccg
    13141 tagaattaac aatctcaacg tcttttggaa ttattttata catatcattt aaaattttaa
    13201 ttactttttt taatggatct ccgtcattac cttcataaaa agaatatatt agctcattct
    13261 tatcatttat taatgcaact ttggtagtag ttgatccagc atcaatacct aaataagctt
    13321 tccctttata acttaataag tcgcctcttt ttacaatagc tttattatgc ctttctttaa
    13381 acactctata ttcttcttca tctctaaata aaggtgtcaa tcttttaaca tcactttctt
    13441 taattgctaa aatccctttg aaactctcaa ctaaatcttt caaagaaact tgtttatttt
    13501 catcacttaa taatgcggct cctatagcta caaacaattc tgcattttca ggagtaatag
    13561 tttgttcttt agttagtctt aacgtttcta caaatctatt tctaagttca gatagaaagt
    13621 ttagtggccc tcccaaaaat gccacatttc ctcttatagg ctttccacaa gctaatccac
    13681 taattgtttg attcacaaca gcctgaaaaa ttgatgcagc aatatcttct ttatgtgcgc
    13741 cttgatttat aagtggttga atatctgttt tagcaaatac accacatcta gatgcaattg
    13801 gataaattac tttaaaagat tttgcatatt catttaatcc ttgagcatct gtattcaata
    13861 aaacagccat ctgatctata aatgcaccag taccaccagc acaacttcca ttcattcttt
    13921 gttctaagcc accattaaaa tacgttatct ttgcatcttc tccaccaagc tctataacta
    13981 catctgtttc aggaatcatg acttcaactg tcttagagca ggcaataacc tcttgtataa
    14041 aatctaaatt aagccattta gaaactgata accctcctga tccagtaaca acaattgaac
    14101 aatcaatatt tcctaaagct tcgtatgcat ttttaactaa atccactata cttattctta
    14161 tatctgaaaa atgtctttga tatttactat aaataatttc atttttatta tctaaaacaa
    14221 ccaactttac tgttgtagat cctacatcaa ttcctattct atacataatt ctacctctct
    14281 tcctatcaat tatttatata tctgaaatat acgttacata tattaataat attattatta
    14341 taaaaaaaga tgacatactt aattgtatgt catcactaaa tttaatcatt catccattca
    14401 taagttttat aactcttttt attatgtgca tgagcaccta ttttttctcc attttcaatc
    14461 cctacttctg aattacctgt aggatcaatt tttctaagtt cattttttga tttagatcta
    14521 tctttcattc tatttttatt attatccata aacatacctc ataaaataat tttttattta
    14581 ttaataatta aacttgcttt taatcgcatt aaatacaggt ctaaaatctt cttcattttc
    14641 atcaaataat ttagttaatt cttctttagc tttaatatac ttttcatcat taatatcatt
    14701 attaactatt ttagatgaat ctttgtggaa tttcataaat attatcggat gtttttttgc
    14761 aaaagcttcc atctcatcta tatgacgttc gggcttagtt gcacttttta accatttaaa
    14821 aacataatca tatttatcca tattcacact tccttttatt tatattttaa agtcagtcgg
    14881 atcatatggt ttagcttttg gttcaccaaa acatgctttt acgctctcca cttgtggatt
    14941 atgacttata tttttctttt gttttttagt ttttttcatt tgatttccca tgtaaatatc
    15001 acctcatcta tatcttgtac atcttctctt ttcttatcct attagaaaat ttccatttgt
    15061 tttataatat tcataaagat gatgcttctc tcattacttc catgttataa aattctataa
    15121 tcatcttatt ttttaactct actgtattgc taaatatcat cttatctgac tataataaac
    15181 ttattaatta tatggaggta ataatgaata atttatatcc gatatctaaa gaaaatttta
    15241 aaaaacttat aaacattcga tttaataata taagtgatgg tttagataat ttcagcaatg
    15301 gaatattaga atgcaatgat aaattacttt cttttacaga gaaagaaaat agatttttaa
    15361 aattttttaa agatacttta ttattaaact ctggtcatat tattatagac ttctacctta
    15421 aaaatcttaa tggtgaagaa atattacatt tactagaagc ccttgatcat aataataaaa
    15481 taattttact acaagaacta aaaaatctta aagatgattc tgtttacttt actctagaca
    15541 ataataattt aatggacttt ataacaattt taaatactcg tgcattattt ttctgcacaa
    15601 tatatttaaa tacttttcct tttacaattt ggggaaatta cgatttaaaa tttcctgttt
    15661 tcttttccga tattaacact ttaaatattt ataaaaattt agctgaaaaa aatggccttt
    15721 caataaattc aataaacata aaaaggggct gtctctgaaa tgatttttaa aatcatttca
    15781 gtagacggtc tttttatttt ttattcatat atttatatga aattatttct aaatgaacaa
    15841 gttttttgac acgacaaata ggaggttata a
//
