LOCUS       NZ_AP019773.1          22396 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_AP019773.1 Bartonella quintana strain MF1-1 chromosome, complete
            genome.
ACCESSION   NZ_AP019773
VERSION     NZ_AP019773.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:02:38
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1551059
            Orig. end    :: 1573455
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22396
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[1561059:1563455]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12396
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..22396
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..22396
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Putrescine2spermidine"
                     /region_number="4"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             123..755
                     /locus_tag="ctg1_1296"
                     /transl_table=11
                     /translation="MKTNHPEHIPITQIKKQLLSSLDKRALVLVGLMGAGKSVIGKRIA
                     TMLGLPFYDSDQEIEKAAQMTIIEFFKVYGESEFRALEQHVTLSLMKKSPLVLATGGGA
                     YINKDIRQVINKNGISIWLKADLDILMKRVSRHPTRPLLQTANPKETMKKLMEQRYPIY
                     AKANLTINSYKESRHTVAQNVIRSVQNYIYTEINDRNNQHANQDRHC"
     CDS             730..1863
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1297"
                     /sec_met_domain="Fe-ADH_2 (E-value: 1.4e-12, bitscore:
                     44.2, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTKTVTVKLDKHCYDIIIGPGLVAQAIWQIKHSLHKKDLHQTRF
                     ALVTDSNVASLHLDTLQAELTKNKIHTVPIIVEAGEQSKSFLTLQIVIDRILAARLERG
                     DCVIAFGGGVIGDLGGFAASIIRRGMNFIQMPTTLLAQIDSSVGGKTGINSRYGKNLIG
                     AFYQPQCVIADTCFLDTLPLREFRAGYAEIVKYGLISQPDFFEWLEKNWQKIFSNGPTR
                     TEAIVRSCQFKADIVARDEHETGERALLNLGHTFGHMLETATAYDSSRLIHGEAVAIGM
                     VLAHQFSAQLNLINPTLIQRVEAHLKAVGLPTQLKDIPGKLPEAETLMTLIAQDKKVSQ
                     NNLTFILTRGLGQSFIAKTVSPETVLAFLEQKLAEIR"
     CDS             1966..2226
                     /locus_tag="ctg1_1298"
                     /transl_table=11
                     /translation="LGTLRRNPQSESAQIRGKLHGRLYANPEPTLSSEEGVETERAAPK
                     GQKLKVKRQSRPQTACQAGDENRSGMNPGAAGSSPAVDTIV"
     CDS             2262..2657
                     /locus_tag="ctg1_1299"
                     /transl_table=11
                     /translation="MKKTLHILGFFSALNLSLFSLTNAFAGSLILEVPDNPEPTTQTIA
                     YQCDTGKSKKHVEAVYLNADNISLVDFKWKGDRVIAANVIADTGVKYAGAQYIWWKTNN
                     EVMLYDLAHDPEEKKPILCKDQSTLLF"
     CDS             2677..3069
                     /locus_tag="ctg1_1300"
                     /transl_table=11
                     /translation="MKKKPFTIRFFVILSLSLFGSINAFADSLIIEIPDNPELITQTSS
                     YQCDMETNKEHVEVTYLTAGNIALVDFKWKGKRIIGSNVIAASGAKYVGGPYIWWTKGN
                     EALLYDLVNDPKEEKPIRCVEEKSTE"
     CDS             complement(3105..3506)
                     /locus_tag="ctg1_1301"
                     /transl_table=11
                     /translation="MKDDVSLAVAIVITFFLILGSGLTLIGTIGLVRFSSFYERLHMLS
                     VAASWGVGSILISSFLYSMLVDHHFVFHEILLMLFLLLTAPVASMLLSQAAAYRHHSDD
                     QSEKPLALLLHQTEEKLPESEKTLCDESQ"
     CDS             complement(3503..3784)
                     /locus_tag="ctg1_1302"
                     /transl_table=11
                     /translation="MSMMILYWGLFFSQFFLSVAMILALFRLIRGPRAQDRIVGLDALY
                     ITAILLFLTFDIRSGTTIYFVAALIIGLLGPVSSIALAKFLMRGEVIE"
     CDS             complement(3781..4266)
                     /locus_tag="ctg1_1303"
                     /transl_table=11
                     /translation="MKYFCPFPFFGAAIVFMWLTLNGFNLGQLLLGIIIALFVGWMRQL
                     LEPEKITIRSWWAVFRLIFRVFIDSISSNVSVAWFVLTKRSREQQSGFIVVPLLLESRI
                     ALAVLVCILSATPGAVWIAYNRKNGELLLHVLNLKNRYNYQQLIKQRYEQLLLEIFS"
     CDS             complement(4263..5885)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Proton_antipo_M"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1304"
                     /sec_met_domain="Proton_antipo_M (E-value: 3.9e-30,
                     bitscore: 101.4, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIGVHHLLILPILLPLITGALLLFYDERRSKLKSLISLFSAGLL
                     VVIAVLLIIRTLKIAPALDVYRLGNWPSSFGIVLVLDRLSAMMLLLSSLLITAALVFAR
                     AHWYKAGPHFQSLMQFFMVGINGAFLTGDLFNLFVFFEVMLTASYGLALHGFGQSRVRA
                     GLHYVVVNLVASLLFLVGTALIYGVVGTLNMADLAIKIKHIAAEDIVLFEIGAAFLGIA
                     FLLKAGMWPLNFWLMPTYSAAVAPVGASFALLSKVGIYIILRLTLLWFGPESGYFSHFG
                     HAILFYGGLATLAFGFIGVLASQVLVRLAAYSVLVSSGTLLATIGIGNIALIAGALFYI
                     VSSTLALGAFFLLVELVERCQDIAANVLTVTMEVYGDDEDEEEDEVGTYFPVTLAILGA
                     CFGICAILIIGLPPFSGFFAKFMMFMAVLNHSKEDFSASLPVYHDWLFVFFVIMSGFAT
                     LIAMTRIGVRTFWVSLEGRVPRVQVIEFAPIAVLLSLCFLITIVAGPVSHYMYETAKTL
                     YEPQNYIGSVLDDFFLEKREMSR"
     CDS             complement(5885..6226)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Oxidored_q2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1305"
                     /sec_met_domain="Oxidored_q2 (E-value: 4.6e-28, bitscore:
                     93.3, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIVLSLGIGVLIGSGIWLVLRPRTFQVILGLSLISYGVNLFMFS
                     MSRPRSNAAPIVDPTTVINPANYVDPLPQALVLTAIVISFATTALFLVILLVSRGLTGS
                     DHVDGREVQ"
     CDS             complement(6226..9147)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Proton_antipo_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Proton_antipo_M"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1306"
                     /sec_met_domain="Proton_antipo_N (E-value: 4e-12, bitscore:
                     42.4, seeds: 433, tool: rule-based-clusters)"
                     /sec_met_domain="Proton_antipo_M (E-value: 7.1e-63,
                     bitscore: 208.8, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTWEAMLILLVLLPFAGSAVISFFRSTAKNNEAWFAGVIALFGL
                     LFTIMLYPAVHGNRVVRLDISWLPEWGSNLILRMDGLSWLFCLLITGIGLLVVVYARYY
                     MDPADSVPRFFAFFLAFMGSMTGIVLSGNLVFLVVFWELTSVFSFLLIGYWYHNASARD
                     GARMALTITGFGGFALFIGVLLIGYIVGSFDLDKVLQSGDMIRSNPLYGSVLICILLGG
                     LTKSAQFPFHFWLPNAMAAPTPVSSYLHSATMVKAGLFLLVRLWPVLSGTESWFWLVGF
                     SGLSTLLLGAYFSMFQQDLKGLLAYSTISHLGLITTLLSLDSPLACVAAIFHMANHATF
                     KASLFMAAGIIDHETGTRDMRKLTGLYRSMPITATLALVASAAMAGVPLLNGFLSKEMF
                     FAEAVEKHMESWLDWIAPYVATLASLFSVTYSVRFIHGVFLGPKPINLPKTPHEPPHFM
                     RLPMEFLVFICLAVGILPNFTIGPILDNAVVSVLGPMTIPYSLVVWHGFNTPLMMSFVA
                     LLGGGLLYAVGHRYFLSCDDGAPFFRHLKGPRIFERILVIISWKWARAVESALSTRCLQ
                     IQLHCIFFVCFAFVGLLLWWDGFISAGPLPLFPLDIPFLALWLVGGLCALLVAWQAKFH
                     RFASLMLLGGAGLMTCATFLWLSAPDLAITQLVVEVVTVVLLLLGLRWLPKRLHHPVPM
                     SVRFFVRLRRVRDFVIALVGGAGVAWLSFAVMTRPQGQTVSDFFLTHAYCSAGGRNVVN
                     VLLVDFRGFDTMGEIVVLGVVSLTVFALLRRFRPAPESIDAPFQQRVQKAFDMAQPGQN
                     VGDTILNYLAVPGVITEWLFSVIIVFSIYLFLRGHDLPGGGFVGGVTLAIGFILQYLAR
                     DIRWVENHLRVLPLRWMGFGLLLSVATGIGAWFFGYPFLTSFFQYTYLPLIGNVPMASA
                     FLFDFGVLSLVLGATVLILIALAHQSIRSYRIGKKPVSREKEN"
     CDS             complement(9344..9829)
                     /locus_tag="ctg1_1307"
                     /transl_table=11
                     /translation="MPIMKSSYYALIIALIGSVFTIVTNITDSAQKSDTEVKASHASPV
                     QENVAPLIFTGRRELNGFKGYRHYRRGYRKYSDDWWYPKTAFVAFPHLNTKHVPLKAIL
                     ASKKMLLISSSEKKEPWMLKQHVDSCRARYRSYNKNDNSYQPFHGPRKQCLSHFFKG"
     CDS             10001..11098
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1308"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 2.4e-09,
                     bitscore: 33.7, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTPYYLIDKSKLIRNMEIITRVREMSGAKILLALKCFATWSLF
                     DLMSEYMDGTTSSSLYELRLGREKFGKETHAYSVAWADDEIDEVCNYADKIIFNSIQQL
                     QRFSKTPKTIQRGLRLNPGISASNFDLANPSRPFSRLGETNQSAIKKILPLINGLMIHN
                     NCENADFNLFDKMLSHMEEQFAELFAAVDWISLGGGIHFTAENYPLETFAERLKHFSKT
                     YGVTIFLEPGEAAITKSTTLEVSVLDTLENEKKLAIVDSSTEAHMLDLLIYRENAKLEP
                     NQGPHEIMVCGKSCLAGDIFGTFRFPEPLKIGDRLSFQDAAGYTMVKKNWFNGLQMPAI
                     VVKESSGALIIQRQFSYNDYQKSLS"
     CDS             11158..12396
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1309"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 1.7e-25, bitscore:
                     86.9, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 4.5e-33,
                     bitscore: 110.6, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKNVLIIGAGGVAQVVTHKCAQNNDVLGEIHIASRTLKKCETIV
                     KSIKDKKAMKVEGILKSHPLNAMNVAETVQLIQKTKCEIVINVGSSFLNMSVLSACIET
                     KCAYIDTAIHEDALKICETPPWYGNYEWPRRQECRNAGITAILGAGFDPGVVNAYAALA
                     RDDYFDKITDIDIIDINAGNHGRWFATNFDPEINFREFTGQVWSWQNKKWTSNQMFEVS
                     REWDLPVVGKQKTYMTGHDEIHSLSKNLDVPNIRFWMGFSERYITVFTVLKNLGLLSEQ
                     PIKTAEGQEVVPLKVVKAVLPNPASLAPDYTGKTCIGDLIKGEKGGKPREVFIYNITDH
                     KQAFNETGAQGISYTAGVPAAAAALLIATGDWDVKTMVNIEELPPHPFLKYLDYMGLST
                     CIREQQEERKLQF"
     CDS             complement(13347..14753)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_dim"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1310"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.1e-71, bitscore:
                     236.8, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="Pyr_redox_dim (E-value: 5.7e-42, bitscore:
                     138.8, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYDVVVIGAGPGGYVAAIKAAQLGFKTAIIEKRMTLGGTCLNVG
                     CIPSKALLHTSEVFAETQHGFEKLGISISKPKLNLEQMMAHKKAVVTANTSGISFLMKK
                     NKIDTFFGTAKILSAGQIEVVARDGNKQTIATKNIVIATGSESSGIPGVNVKIDEKIIV
                     SSTGALALEKVPMRMIVVGAGVIGSELGSVWSRLGSKVTIIEYLNKVLGSMDGEVSRQF
                     QKLMEKQGIEYKTGTKVTDIMQSGSTAQVTFETIKGGASETLEADVVLIATGRFPYTEG
                     LGLVEAGVQLDERGFIAIDANWQTNIPGIYAIGDVVKGPMLAHKAEEEGVAVAEILAGQ
                     KGHVNFDVIPSVVYTQPEIASVGKTEEELKAAGIDYNVGKFLFTANGRARAMQKSDGFV
                     KILADKKTDRVLGGHILGFGASEMIHEIAVLMEFGGSSEDLGRCCHAHPTLSEAVREAA
                     LATFAKPLHI"
     CDS             complement(14786..16018)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) oxoacid_dh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: -0.6; E-value:
                     4.3)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1311"
                     /sec_met_domain="Biotin_lipoyl (E-value: 5.8e-20, bitscore:
                     67.3, seeds: 40, tool: rule-based-clusters)"
                     /sec_met_domain="oxoacid_dh (E-value: 1.4e-82, bitscore:
                     272.9, seeds: 75, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTGIRVPTLGESVTEATIGKWFKKLGEAVAVDEPLVELETDKVT
                     VEVPSPVMGKLTEIIAKEGDIVEVNAVLGFVESGAAGISQSFSPSATFIPEAPSELEQS
                     PSSSATPSGTMPPAPSAAKLMAENNIAKSDISGSGKRGQILKEDVLGALAQGTKASTSV
                     ATLTASSSSAAPIQEMREERVRMTKLRQTIARRLKDAQNTAAMLTTFNEVDMSAVMDLR
                     KRYKDLFEKKHGVKLGFMGFFTKAVCHALKEFPTVNAEIDGTDIVYKNYVNAGIAVGTD
                     KGLVVPVVRDADQMSLAEIEKEISRLGRLARDGKLAVSDMQGGTFTITNGGVYGSLMST
                     PILNAPQSGILGMHAIKERAMVVGGQIIICPMMYLALSYDHRIVDGQEAVTFLVRVKES
                     LEDPERLVLDL"
     CDS             complement(16050..19049)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) E1_dh"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transket_pyr"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1312"
                     /sec_met_domain="E1_dh (E-value: 6.2e-62, bitscore: 205.5,
                     seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="Transket_pyr (E-value: 2.8e-67, bitscore:
                     222.2, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARQDEINSLFAQTSFLYGGNANYIDQLYAEYEKNPSSVDSQWRA
                     FFETLQDNKEDVLKNAQGATWRREHWPLKESGELVSALDGDWFALEKHLSGKLKEKIAT
                     GVTQKGKTSSKQDIIQATRDSVHALMMIHAFRARGHLHARLDPLQLAEKLEDYKELSPE
                     AYGFTSADYERSIFIDNVLGLEYATIPQMLEILNRTYCSTIGVEYMHISDPAQKAWLQE
                     RIEGPDNRISFTPKEKKAILNKLIEAEGFEQFLDIKYKGTKRFGIDGGEALIPALEQII
                     KYGSTLGVQEVVLGMAHRGRLNVLSQVLAKPHQAIFHEFKGGSYKPDDVEGSGDVKYHL
                     GTSADLEFDGKKLHLSLLANPSHLEIVNPVVIGKTRAKQDQLVGTARTEVISLSERAKV
                     LPLLIHGDAAFAGQGVIQETFGLSGLKGYRVAGSIHVIVNNQIGFTTDPRFSRSSPYPS
                     DVAKMIDAPIFHVNGDDPEAVVFIAKIATEFRQIFHKPVVIDMFCYRRYGHNEGDEPSF
                     TQPLMYKAIRNHKTTLQLYGDQLVKEGVISLEEIEQQKKLWRDKLEAEFEASTSYKPSK
                     ADWLDGSWTGLKASSNTEEQYFGTTGVALKTLKEIGQKLVEIPPNFHVHKTIQRFLSNR
                     AKVFETGEGVDWATAEALAFGSLCLEGASVRLSGEDVERGTFSQRHSVLYDQENEARYI
                     PLNNLQKGQGIYEVVNSMLSEEAVLGFEYGYSLAEPHGLTLWEAQFGDFSNGAQVIFDQ
                     FISSAERKWLRMSGLVCLLPHGFEGQGPEHSSARLERFLQLCAEDNMQVANCTTPANYF
                     HILRRQIKRDFRKPLILMTPKSLLRHKRAVSFLNEMGPETRFHRLLLDGAELLKNSVVK
                     LQKDNKIRRIVLCTGKVYYDLYEEREKRGINDVYLLRIEQLYPFPAKALVDVLSRFLQA
                     EIVWCQEEPKNMGAWSFIEPYLEWVLTHINAQYSRARYVGRPASASPATGLMVKHLEQL
                     SAFLEDALSS"
     CDS             complement(19209..20111)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Ligase_CoA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CoA_binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1313"
                     /sec_met_domain="Ligase_CoA (E-value: 9.8e-21, bitscore:
                     70.5, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="CoA_binding (E-value: 1.4e-24, bitscore:
                     83.0, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSILIHQNTKVLVQGLTGKTGTFHTEQALAYYGTKMVGGVHPKKG
                     GEVWEGSRGESLPIFASVAEGKERTGADASVIYVPPSGAADAIIEAIEAEIGLIVCITE
                     GIPVMDMVKVKVKLEQSKSRLIGPNCPGILTPHACKIGIMPGSIFRKGSVGVVSRSGTL
                     TYEAVFQTSQEGLGQTTAIGIGGDPVKGTEFIDVLELFLADDETESIVMIGEIGGSAEE
                     EAAQFLKDEAKKGRKKPIVGFIAGRTAPPGRTMGHAGAVISGGKGGAEDKIAAMESAGI
                     HVSPSPSQIGKTLMVLLRG"
     CDS             complement(20115..21311)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Ligase_CoA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1314"
                     /sec_met_domain="Ligase_CoA (E-value: 3.5e-28, bitscore:
                     94.7, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIHEYQAKRLLHEYGAPIANGVAVYSVEQAEKWAKKLPGPLYVV
                     KSQIHAGGRGKGKFKELDLDSKGGVRLAKSVEEVVANVKEMLGKTLVTKQTGPEGKQVN
                     RLYIEDGADIERELYLSLLVDRAVGRVAFVVSMEGGMDIETVAEETPEKILTLPVDPVQ
                     GVTSADCKRLCDALELHDNGRKDGEKLFPILYKAFCEKDMSLLEINPLIVMKDGHLRVL
                     DAKVSFDNNALFRHPDILELRDLSEEDPKEIEASKHDLAYVALEGTIGCMVNGAGLAMA
                     TMDIIKLYGAEPANFLDVGGGASKEKVTAAFKIITADPNVKGILVNIFGGIMRCDVIAE
                     GVVAAVREVGLKVPLVVRLEGTNIEQGKAIISDSGLNVVSASDLDDAAQKIIAAVRGA"
     CDS             complement(21407..22369)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Ldh_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Ldh_1_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1315"
                     /sec_met_domain="Ldh_1_C (E-value: 1.4e-33, bitscore:
                     112.5, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Ldh_1_N (E-value: 3.2e-40, bitscore:
                     133.8, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARKKIALIGSGMIGGTLAHMIGLKELGDVVLFDIEEGMPQGKAL
                     DIAESSPVDGFDVSLTGANVYEAIEGADVVIVTAGVARKPGMSRDDLLGINLKVMEQVG
                     VGIKKYASSAFVICITNPLDAMVWALQKFSGLPKQKVVGMAGVLDSARFRYFLSKEFKV
                     SVKDVTAFVLGGHGDSMVPLVRYSTVGGISLPDLVKMGWTTQEKIDQIIQRVRNGGAEI
                     VGLLKTGSAFYAPAASAISMAEAYLKDIKRVVPVAAYLSGEYGVKDTYVGVPVVLGAGG
                     VERVIEIDLDKKERSAFEQSVNAVKKLCEACIAIAPCLK"
ORIGIN
        1 atcaaaaatc tagtcaatgt tggcataaga taatactatc caaaaatact ctatcactta
       61 atcatgcctt ataaagatta acaggaattg actttaaggc ggataaatgc cgaaataaag
      121 tcatgaaaac taatcatccc gaacatatcc cgataacaca aataaaaaag cagcttttat
      181 cgtctcttga taaacgagca cttgtacttg ttggtcttat gggtgcaggc aaatcagtaa
      241 tcggaaaacg cattgctacc atgctcggtt tgcccttcta cgattctgac caggaaattg
      301 aaaaagctgc acaaatgaca atcattgaat tttttaaagt ttatggtgaa tcagaattcc
      361 gtgctcttga acagcatgtt actctaagcc tcatgaaaaa aagtcctctt gttttagcaa
      421 caggtggcgg tgcctacata aataaagata tccgacaagt cattaataaa aatggtatat
      481 ctatatggct caaagcagat cttgatattc tcatgaaacg tgtttcgcga cacccaacgc
      541 gaccactcct tcaaacagca aaccctaaag aaaccatgaa aaaactcatg gaacaacgct
      601 accctatcta tgcaaaagca aacttaacaa ttaacagtta taaggaaagc cgccatactg
      661 tagcacaaaa tgttatacgg tctgtacaga actacatcta tacagaaatt aacgatagga
      721 ataaccagca tgcaaaccaa gaccgtcact gttaaactgg acaagcactg ttacgacatc
      781 atcattggtc caggtctggt cgcacaagct atttggcaga ttaagcattc gcttcacaaa
      841 aaagatcttc atcaaacgcg ttttgcactt gttacagata gcaatgttgc atctctccac
      901 ttagatacat tacaagcaga attaacaaaa aataaaatcc atactgttcc aattattgtc
      961 gaagcaggcg agcaatcaaa atcattttta actctgcaaa tcgtcattga tagaattctc
     1021 gctgcgcgtt tagaaagagg cgactgcgtc attgcttttg gtggtggtgt cattggcgac
     1081 ctaggagggt ttgccgcaag tattatacgc cgtggaatga acttcattca aatgcccaca
     1141 acgcttctcg cacaaattga ctcttctgtt gggggaaaaa cgggaatcaa tagccgatat
     1201 ggtaaaaatc ttattggcgc tttttatcaa ccgcaatgcg ttattgctga cacgtgtttc
     1261 cttgatacac taccattacg tgaatttcgc gctggctacg cggaaatagt caaatacggt
     1321 cttattagcc agcctgattt ttttgagtgg ctcgaaaaaa attggcaaaa aattttttcg
     1381 aatggcccaa cacgaacgga agccattgtc cgctcatgtc agtttaaagc tgacattgta
     1441 gcacgcgacg aacacgaaac aggagaacgt gcattattaa accttggtca tacatttgga
     1501 cacatgcttg aaacagcaac tgcttacgac tcaagccgtt taatccacgg cgaagctgta
     1561 gcaattggga tggttctagc acaccaattc tctgctcaac taaatttaat aaaccccacc
     1621 ctcatacaac gcgttgaagc acacctcaaa gcagtgggat tgcctacgca gctaaaagat
     1681 atcccaggga agctccccga ggctgaaaca ttgatgactc tcattgcgca agataaaaaa
     1741 gtttcgcaaa acaatttgac cttcatctta acgcgcggcc ttggtcaatc atttattgca
     1801 aaaactgttt caccagaaac agttttggct tttctggaac aaaaattggc ggaaattcgt
     1861 taattcatat tgaatataat tgattcgttt ttatacttct attacaagga ttaatgatga
     1921 tgtctgcgta gctcagtagg atagagcaca ggattcctaa agaaattggg cactttaagg
     1981 agaaatcctc aaagtgaatc tgctcaaatt cggggaaagc ttcatgggag actatatgcc
     2041 aatcccgagc caaccctctc ttcagaggaa ggtgtagaga ctgaacgggc agcacctaaa
     2101 ggacaaaagc tcaaggtgaa gagacagtcc agaccacaaa cagcctgtca agctggcgat
     2161 gaaaatcgaa gtggtatgaa tcctggggcc gcaggttcga gtcctgccgt agacaccatc
     2221 gtataagtca aattattctt tctgcacagt aaggaagtat tatgaaaaaa actttacaca
     2281 ttttaggatt tttctccgct ttaaacctat cactcttcag cttaaccaat gccttcgctg
     2341 gttctttaat ccttgaagta ccagacaatc cagaaccaac aacacagacc attgcttatc
     2401 agtgcgatac tggaaaaagt aaaaagcatg ttgaagcagt ctatcttaat gctgataata
     2461 tttcgttggt tgatttcaaa tggaaaggtg atcgcgtcat tgccgctaat gtcattgctg
     2521 acacgggagt aaaatatgca ggggcccaat acatctggtg gaaaaccaat aacgaagtca
     2581 tgctttatga tcttgctcat gacccagaag aaaaaaaacc tatcctctgt aaagatcaat
     2641 caacattatt attctgaata acatttagaa agtattatga aaaaaaaacc ttttactata
     2701 cgatttttcg tcattttaag tctatcactc ttcggttcaa tcaatgcctt tgctgattct
     2761 ttaatcattg agataccaga taatccagag ctgataactc agacaagttc ttatcaatgt
     2821 gatatggaaa caaacaaaga gcatgttgaa gtaacctatc tcactgccgg caacattgcg
     2881 ttagttgatt tcaaatggaa aggaaagcgc atcataggtt ccaatgtcat tgctgcttct
     2941 ggagcaaaat atgtgggagg tccatatatt tggtggacaa aaggaaacga agccttactt
     3001 tatgatctcg ttaatgatcc aaaagaagaa aagcccatcc gctgtgtaga agaaaaaagc
     3061 acggagtaaa atagagctgt tgcatttcaa aaactgcgtt ggctttattg gctttcatca
     3121 cataatgttt tttctgattc gggaagcttt tcttctgtct gatgtaataa aagagccagc
     3181 ggcttttctg actgatcgtc tgagtggtgt cgataagccg ctgcctgtga gagcaacatg
     3241 gaagcgaccg gtgctgttag gagcaaaaaa agcatcagca atatttcatg aaaaacaaaa
     3301 tgatgatcca caagcattga gtaaagaaac gaagaaatga gaatgctgcc aacgccccag
     3361 cttgcagcca ctgaaagcat atgcaaacgc tcataaaaac tggaaaaacg cactaaacct
     3421 atcgttccta tcagtgtcaa tccagatccc aatattaaga aaaaagtgat aacaatagcg
     3481 actgcaagcg atacatcatc cttcattcaa taacttctcc acgcattaag aacttcgcca
     3541 aagcgatact tgaaacagga cctaaaagcc caataatgag agccgctaca aaataaatag
     3601 ttgttcctga gcgaatatcg aatgtaagaa acaaaagaat agcggttata taaagagcat
     3661 ccaaaccaac gatccgatcc tgcgcccgtg gaccacgaat caaccgaaac agtgcaagga
     3721 tcatcgccac acttaaaaaa aactgcgaaa agaaaagccc ccaataaagg atcatcatgc
     3781 tcatgagaaa atctccaaaa gcagttgctc ataccgttgt ttgatcaact gttggtaatt
     3841 atatctattt tttaaattca agacatgaag caaaagttca ccattttttc tattataggc
     3901 aatccaaaca gctccaggag ttgctgaaag tatacaaact aaaacagcca aagcaatgcg
     3961 actttcaagc aaaagaggga ccacaataaa acccgactgc tgttctcgag atctttttgt
     4021 taaaacaaac caagctactg aaacatttga ggatatagaa tctataaata ctcgaaaaat
     4081 gagacgaaaa accgcccacc aacttctaat agtgatcttt tccggttcaa gaagctgcct
     4141 catccaacca acaaacaaag caattataat gcctaaaagc aattgaccca aattaaaacc
     4201 atttaaagtc agccacataa aaacaattgc cgcaccgaaa aaagggaaag gacaaaaata
     4261 tttcatcgac tcatttccct cttttcgaga aaaaaatcat ctaaaacgct cccaatgtaa
     4321 ttctgaggtt catacaaagt cttagcagtt tcatacatat aatgactaac aggaccggct
     4381 acaattgtta taagaaaaca caaagaaagg agaacagcaa taggcgcaaa ttctatcact
     4441 tgtacacggg gaaccctccc ttcgagagaa acccaaaaag ttcgaacacc tattcgtgtc
     4501 atagcaatca aagttgcaaa accagacatg atgacaaaaa aaacaaaaag ccaatcatgg
     4561 taaaccggta gagaagcaga aaagtcctct ttactatgat ttaaaaccgc catgaacatc
     4621 ataaatttag caaaaaaacc agaaaaaggc ggcaacccaa taatcaaaat ggcacaaata
     4681 ccaaaacaag ccccgagaat cgccaaggtt actggaaaat aggtaccaac ttcatcttct
     4741 tcctcatctt catcatcgcc atacacttcc attgtaacag tcaaaacatt ggcagctata
     4801 tcttgacagc gttcaactaa ctccaccaga agaaaaaaag cgccgagtgc taaagttgaa
     4861 gaaacaatat aaaaaagtgc acctgctata agtgctatat tgccaattcc gattgttgct
     4921 aacaatgtac cagaagatac aagaacgcta taagccgcta aacgcaccaa gacctgactt
     4981 gccaatactc caataaaacc aaaagccaga gtggcaagtc caccataaaa caaaatcgca
     5041 tgaccaaaat ggctaaaata tccactttca ggaccaaacc atagcagtgt taaacgtaaa
     5101 atgatataaa tacccacctt gcttaaaagt gcaaaagaag ctccaacggg cgctactgct
     5161 gcactgtaag tcggcatcaa ccaaaaatta agcggccaca tacctgcttt gagcaaaaag
     5221 gcaattccca aaaatgcagc acctatttcg aataaaacaa tatcctcagc agctatatgc
     5281 tttattttga tagctaaatc ggccatatta agagtgccca caactccata aatgagtgct
     5341 gtaccaacta aaaaaagtaa cgaagcaaca agattaacca caacataatg caaccctgca
     5401 cgcacacgtg actgaccaaa accatgcaaa gcaagcccat aagaagctgt taacataact
     5461 tcaaaaaaca caaataaatt gaacaagtca cctgttaaaa aagcaccatt tatccccacc
     5521 atgaaaaatt gcatcagtga ctgaaaatga ggaccagctt tgtaccaatg agctcgcgca
     5581 aaaaccaacg cagcagtgat taacaagctg gaaagcaaaa gcatcatagc gcttaaacga
     5641 tcaagaacca aaacaattcc gaaggaagag ggccaatttc caagccgata aacatccaaa
     5701 gctggtgcta ttttaagagt acgaataatc aataaaacag caataacaac caacaatcca
     5761 gcagaaaaaa ggcttattaa tgatttaagt tttgaacggc gttcatcata gaaaagaaga
     5821 agtgctccag taattagtgg caaaaggata ggcaaaataa ggagatgatg taccccaatt
     5881 ttcatcactg aacctcacgt ccatcaacgt gatctgaacc cgttaaaccg cgtgaaacca
     5941 gaaggataac caaaaacaaa gctgtcgttg caaaactaat cacaattgcg gttaaaacca
     6001 aggcctgtgg gagaggatcg acataattag ctggattgat aacagtagta ggatcaacaa
     6061 ttggcgcagc attactgcgc ggtctactca ttgaaaacat gaaaagattg acaccatagg
     6121 agattaaaga caaaccaaga atgacctgaa aagttcgtgg acgtaaaaca agccaaatgc
     6181 ctgatccgat aagaacaccg atgcctaaag aaagaacaat ttccattaat tctccttctc
     6241 tctcgaaaca ggttttttac cgattcggta actacgaatc gactgatgtg ccagcgcaat
     6301 taaaatgaga acagttgctc ccaacacaag agaaagcaca ccaaaatcaa acaaaaaagc
     6361 agatgccatt ggaacatttc caattaacgg aagatacgta tattgaaaaa aggacgttaa
     6421 aaaaggatac ccaaaaaacc aagcccctat tcccgttgct acggacaaca ataagccaaa
     6481 gcccatccag cgcaaaggca aaacccttaa atggttttct acccaacgaa tatcacgtgc
     6541 aagatattgt aaaataaagc ctatcgctaa agtcacacca ccaacaaatc cgcctcctgg
     6601 gagatcatgc cctcgcaaga ataaataaat agaaaaaaca ataataactg aaaagagcca
     6661 ctccgtaata acaccaggaa cagctagata attcaatatt gtatccccca cattctgacc
     6721 aggctgtgcc atatcaaaag ctttctgaac acgttgctga aaaggcgcat caatactttc
     6781 aggagcagga cgaaaccgtc gcaaaagagc aaaaacagtg agagaaacaa cacccaaaac
     6841 cacaatttcc cccatagtat caaaaccacg gaaatcaacc aacaaaacat ttacaacatt
     6901 gcgaccacca gcactgcagt aagcatgagt cagaaaaaaa tcagaaactg tctgaccttg
     6961 agggcgtgtc atcactgcaa aagaaagcca tgctacacca gcacctccca caagtgctat
     7021 gacgaaatca cggacacgac gtaagcgaac aaaaaaacga acggacattg gaacaggatg
     7081 atgcaaacgt ttaggcaacc accgcaaacc aagcaataat aagacaactg tcacaacttc
     7141 aaccaccagt tgtgttatcg ctaaatcagg tgcagaaagc cataaaaaag tcgcacaagt
     7201 catcaaacca gctcccccta acaacatgag tgatgcaaaa cgatgaaact ttgcttgcca
     7261 agcaactaaa agcgcacata atccgccaac caaccaaaga gcgagaaaag gaatatcaag
     7321 aggaaaaagt ggtaatggcc ccgctgaaat gaaaccatcc caccaaagta aaagaccaac
     7381 aaatgcaaaa cacacaaaaa aaatacagtg caactgtatc tgcaaacagc gtgttgacaa
     7441 agcagattcc actgcacgtg cccatttcca agaaataatc acgagaatgc gttcaaaaat
     7501 acgtggccct ttcaaatgac gaaaaaaagg ggctccatca tcacaggata aaaaataacg
     7561 atgtccgaca gcatagagta atccgcctcc taataaagca acaaagctca tcattaatgg
     7621 agtattaaac ccatgccaaa caaccaaact ataagggatt gtcatcggtc ctaaaacaga
     7681 tacgactgca ttatctaaaa tgggccctat tgtgaaatta ggcaaaatac caaccgccaa
     7741 acaaataaac accaaaaatt ccattggtaa acgcataaaa tgtggtggtt catgtggagt
     7801 tttgggtaag ttgataggtt ttggtcctaa aaaaacacca tgaataaagc gtacagaata
     7861 ggtgacacta aataggctag caagcgttgc cacataaggt gcaatccaat cgagccatga
     7921 ttccatatgt ttttcaacag cttcagcaaa gaacatttct tttgataaaa aaccattcag
     7981 caaaggaact ccggccatag ctgcactcgc caccaaagcg agagttgctg taataggcat
     8041 agagcgataa agacctgtca gcttacgcat atcacgtgtc cccgtttcgt gatcaataat
     8101 gccagctgcc ataaataaag aagctttaaa agtagcatga ttggccatat gaaagatcgc
     8161 cgcaacacat gcaagtggac tatcaagact taaaagcgtt gtaatcaatc caagatgact
     8221 aatggttgag taagcaagca gaccttttag atcttgctga aacatagaaa aataagcgcc
     8281 aagcagcagt gtagagagtc ctgaaaaacc aaccagccaa aaccaggatt ctgtcccgga
     8341 taatactggc cataaacgaa caagcaaaaa caaccctgct tttaccattg tcgccgaatg
     8401 caaataagat gatacaggtg ttggagcagc catcgcatta ggcaaccaaa aatgaaacgg
     8461 aaactgtgcg ctttttgtta atcctcccaa taaaatacaa ataaggacag aaccataaag
     8521 aggatttgac cggatcatat ctccagactg caatacctta tccaaatcaa aactgccaac
     8581 gatataccca atcaataaaa ccccaataaa aagggcaaaa ccaccaaaac ctgtgattgt
     8641 taaagccata cgtgcaccat cacgcgcgct tgcattatgg taccaatagc caatcaacaa
     8701 aaaagaaaaa acactggtga gttcccagaa aactaccaaa aaaacgagat tacccgacaa
     8761 gactattcct gtcattgaac ccataaaagc taaaaaaaag gcaaaaaatc gcggtacgga
     8821 atccgccgga tccatgtaat aacgcgcata gacgacaaca agcaacccaa ttcctgtaat
     8881 gagcaagcaa aaaagccacg acaaaccatc catacgaaga atcaaattac tcccccattc
     8941 tggaagccaa gaaatatcta aacgcaccac acggtttccg tgaactgctg gataaagcat
     9001 tattgtaaaa agaagcccga acagtgcaat aaccccagca aaccacgctt cattattttt
     9061 tgctgtcgaa cgaaaaaagc taataacagc acttccagcg aagggaagca aaaccagcaa
     9121 tatcaacatt gcttcccatg ttgtcattct ttaagctccg tcttggcttt aacattttgt
     9181 tgatgacaaa atgaaaattt acatttttat caccccattt tgcccttaca ataataagat
     9241 ttaataaacc ttaaaaatat ttaaaatttt tacaaaacaa ccattggatg aaaaactgct
     9301 caacacacaa aatgtcttaa aaaattttca tctttaacat tttctatccc ttaaaaaagt
     9361 gagaaagaca ctgcttacga ggtccatgaa aaggctgata gctattatca tttttattgt
     9421 aagaacgata acgcgcacga caagaatcaa catgttgttt gagcatccat ggctcttttt
     9481 tctctgaaga agaaatcaaa agcatttttt tcgaagctaa tattgctttt aatggcacat
     9541 gctttgtatt tagatgtgga aatgcaacga atgccgtttt aggataccac caatcgtcac
     9601 tatatttacg ataaccgcgt cgataatgac gatagccttt gaaaccgtta agttccctgc
     9661 gccctgtaaa aattaaagga gccacatttt cttgaactgg agatgcgtga gatgccttaa
     9721 cttcagtatc gcttttttgc gcagaatcag tgatattggt tactattgta aaaacacttc
     9781 cgatgagtgc aataatcaaa gcataatacg aactcttcat tataggcata acacaaatct
     9841 cacaaaaaac gaaccaaaat tagattccag acaatctctc tatcactaaa cgatacgcag
     9901 attctctttt atgcttcttt ttcacttgag acattctgct actccatgta ctaaacgttg
     9961 atctcaagaa taagatcctt caaaaatgaa tggataaaca atgattagaa ctccctatta
    10021 tcttatcgat aaatctaaac tcataaggaa tatggaaatc atcactcgcg taagagaaat
    10081 gtcaggagca aaaattttgc tggctttgaa atgctttgct acgtggagtc ttttcgattt
    10141 aatgtccgag tatatggatg gaacaacatc atcatcgctg tatgaactgc gtttaggaag
    10201 agaaaaattt ggtaaagaaa ctcatgctta ttcagttgcc tgggcagatg atgaaattga
    10261 tgaagtttgt aattatgccg ataaaattat ctttaattcc atccaacagc ttcaacgttt
    10321 ttctaaaaca ccaaaaacta ttcaacgggg tttaaggtta aatccaggaa tcagtgcatc
    10381 aaactttgat cttgcaaacc cctctcgccc ttttagccgc ttaggcgaaa ctaaccaaag
    10441 cgctattaaa aaaattttgc ctctcatcaa tggcttaatg atccacaata actgtgaaaa
    10501 tgctgatttt aatcttttcg acaaaatgct tagtcatatg gaagaacaat tcgcagaact
    10561 ctttgctgcg gttgactgga taagtcttgg aggtggaatc cattttacgg ctgaaaatta
    10621 tcctctagaa acttttgcag aacgcctaaa acacttttca aaaacctatg gagtcaccat
    10681 ttttctagaa ccaggagaag ctgctattac caaaagcacg acactagaag taagtgtact
    10741 tgacacattg gagaatgaaa aaaaactcgc tatcgttgat agctcaacag aagcccatat
    10801 gcttgatctt ttaatttatc gtgaaaacgc caaactagaa cccaatcaag gtccccatga
    10861 aattatggtt tgcggaaaat cttgtcttgc tggtgatatt tttggaacat ttcggttccc
    10921 tgaacccctt aaaataggtg atagattatc ttttcaagat gctgcaggct atacaatggt
    10981 caaaaagaac tggtttaatg gccttcaaat gcctgccatt gtcgttaaag aatctagcgg
    11041 agctctaata attcaacgcc aatttagcta taatgattac caaaaaagcc tttcataacg
    11101 caaatcatat acaaaaaaac catcatgcgg caatattaag aaggagataa ccccaaaatg
    11161 aagaaaaatg ttcttattat tggtgccgga ggtgttgcac aagttgttac gcataaatgc
    11221 gcacaaaaca acgatgttct cggtgaaatt catatcgctt cacgaacact taaaaaatgt
    11281 gaaacaattg ttaaatccat taaagacaaa aaagcgatga aagtagaagg cattcttaaa
    11341 agccatccac tcaatgcaat gaatgttgca gaaactgtac aactcattca aaaaaccaaa
    11401 tgcgaaattg ttatcaatgt tggctcctct tttcttaata tgtctgttct ctcagcttgt
    11461 atcgaaacta aatgtgctta tatcgatacc gcaattcatg aagacgcttt gaaaatttgt
    11521 gaaacacctc cctggtatgg caattatgaa tggccgcgac gtcaagaatg tagaaatgct
    11581 ggcataacag ccattttagg tgcaggcttt gatcctggtg ttgttaatgc ttatgcagcg
    11641 ttagcgcgtg atgattattt cgacaaaatc accgatattg atattattga tattaatgcc
    11701 ggaaaccatg ggcgttggtt tgctacaaat tttgatccgg aaattaactt tcgcgaattt
    11761 acaggacagg tatggtcatg gcaaaataaa aaatggactt ctaatcaaat gtttgaagtc
    11821 agccgtgaat gggatctccc cgttgttgga aaacaaaaaa cctatatgac ggggcatgat
    11881 gagattcatt cattatctaa aaatcttgat gttccaaata ttcgattctg gatgggattt
    11941 agtgaacgtt acataaccgt ttttaccgtt ttgaaaaatc ttggactctt atcagaacaa
    12001 ccaattaaaa cagcagaggg tcaagaagtc gtccctttaa aagtcgtaaa agccgtcttg
    12061 ccgaatccag cttctttagc gccagactat acaggaaaaa cctgcattgg agatcttatt
    12121 aaaggcgaaa aaggtggaaa accaagagaa gtttttattt ataatataac tgatcacaaa
    12181 caagccttca atgaaaccgg tgcacaaggt atttcctata cagctggtgt accagcagct
    12241 gctgctgctc ttcttattgc cactggcgat tgggatgtta aaaccatggt aaacatagaa
    12301 gaattaccac cgcatccctt cctcaaatat ctcgattata tgggactttc tacctgcata
    12361 agagagcaac aagaagagag aaaattacag ttttaaattt atttttatat aagaagaaag
    12421 atacagaaaa ccgctcctaa aaaagagcgg ttttttaaaa atatacaatg tatcaatcca
    12481 ccaaaaataa aaggcacctt ttacgcttct tcaaaaagca tcataaaact ccctaaaaaa
    12541 gtttgtccag attctatgtt ttattcttct aagtcggaag acgattaaaa cagagaccaa
    12601 gaacctcata aaaaagaggt tttttatcaa atcgttagaa taaacatctg aatagcattt
    12661 tttgtgaaga tattcattca tgacgcagta ttttcttagt cgagtggaag gaaagaatag
    12721 agatacagtc ctgctttccc atctcttcac gcctctgtag ccttcaacag caataactta
    12781 tgtattttca aaacactcaa caagctgaga ggcttggtaa tatcactcga attccctgga
    12841 gtgagaagga aatataaaaa ttaactcaag gcacccatta cagcatgacg cttcattgtt
    12901 aaatcttggc ttttttacca acgtttcctt ctcatgttga ccttatctat aagcctgcaa
    12961 cataattata cagataggaa tgaacctgga taaaggagac attgattctc acgaattgat
    13021 agtccttgac aagctcttcc aaaattggat gccacccccc cttttttctg atacaagaat
    13081 catagcgttt atcagttagt tctagggact tgtttaaaga ataaggagaa gaagctcttg
    13141 ccatttaaaa taaaatgaac agcttgaaaa aacaacgggt aaggttttca gtcctcacgt
    13201 gtatcccaga aacttattct ccataaattt taaatccttt ggcaacacct ggattaatgt
    13261 aagagctctt cctggtaaca tacctgttct taacaaacgg aacgttacca gttttattct
    13321 caaatcttaa cgaagatgcc cataacctaa atatgaagcg gtttagcaaa tgtcgccaaa
    13381 gctgcttctc gcactgcttc tgataaagta gggtgcgcat ggcaacaacg ccctagatct
    13441 tctgatgaac caccaaattc catcaaaact gcaatttcat ggatcatttc actagcacca
    13501 aacccaagaa tgtgtccgcc caaaacccga tctgtctttt tatcagcaag gattttaaca
    13561 aacccatcac ttttttgcat cgcgcgtgca cgaccattgg ctgtgaaaag aaactttcca
    13621 acattataat caattccagc agctttcagt tcttcttctg tcttgcctac actagcaatt
    13681 tctggctgtg tataaacaac actaggaatg acatcaaaat taacatgtcc tttttgacct
    13741 gccaaaattt ctgccacagc aacgccttct tcctctgcct tatgcgctaa cattggtcct
    13801 ttaacgacat caccgatcgc ataaattcct ggaatatttg tctgccaatt tgcatcgatt
    13861 gcaataaagc cacgttcatc caactgaaca ccagcctcta ctaagccaag cccctccgta
    13921 tacgggaagc gcccagtagc aatgagcaca acatcagcct ctaaagtttc tgatgcacca
    13981 cctttgatgg tttcaaaggt tacctgagcg gttgaaccag attgcataat atctgttacc
    14041 tttgtaccag tcttatattc aattccctgt ttttccatta atttctgaaa ttgccgtgaa
    14101 acttcaccat ccattgatcc taaaacttta ttaagatatt caataatggt aaccttagaa
    14161 cctaagcggc tccaaactga accaagctct gaaccaatga caccagcgcc aaccacaatc
    14221 atacgcattg gtactttttc aagcgcaagg gctcctgtag aagacacaat aatcttttca
    14281 tcaattttaa cattcacacc tggaatgccc gaactctctg aaccagtagc aataacaata
    14341 ttttttgtcg cgatcgtttg tttgttacca tctcttgcaa caacttcaat ctgacctgcg
    14401 cttaaaattt tagctgtacc aaaaaaagtg tcaattttat tctttttcat caaaaaagaa
    14461 atgccacttg tatttgctgt tacaacagct ttcttatgcg ccatcatttg ctcaagatta
    14521 agcttaggtt ttgaaataga aataccaagc ttttcaaaac catgttgcgt ttcggcaaac
    14581 acttctgaag tgtgcaataa cgctttagaa ggaatacagc caacattaag acacgtaccg
    14641 cctaatgtca tgcgcttttc aataatcgct gttttaaagc ccaattgcgc tgctttgatt
    14701 gccgctacat aaccacctgg acctgccccg attacaacca catcataaga catccgtttt
    14761 ccctttcatc ctgaaaactg tacttttaca aatcaagaac aaggcgttcc ggatcttcta
    14821 aactttcctt aacacgcaca aggaaagtca cagcctcttg tccatctaca atacggtgat
    14881 cgtaagaaag cgccagatac atcatggggc aaattataat ttgcccccca acaaccattg
    14941 ctcgttcttt aatcgcatgc attcccaaga taccagactg tggtgcattc aaaatcggtg
    15001 tcgacattaa cgacccataa acaccgccat tggtaatcgt aaaagttcca ccttgcatat
    15061 cagaaaccgc taattttcca tcacgagcga gacgacctag acggctaatc tctttttcaa
    15121 tctcggcaag tgacatctga tctgcatcac gaaccactgg aacgacaagt cctttatctg
    15181 ttccaacagc aatgccagcg ttgacatagt ttttgtaaac aatatctgtt ccatcaattt
    15241 ccgcattaac agtaggaaat tcttttaatg catggcaaac agctttggta aaaaatccca
    15301 taaagccaag tttaacacca tgtttctttt caaaaagatc cttataacgc ttgcgcaaat
    15361 ccattaccgc agacatatca acttcattaa atgtagttaa cattgccgct gtattttgtg
    15421 catctttaag gcggcgagca attgtttgac gcaattttgt catacgaacc cgctcctcac
    15481 gcatttcctg aataggcgca gccgaagagc tggatgcggt aagagtggca acagaggtag
    15541 atgcttttgt tccttgtgct aaggcaccaa gaacatcttc cttgagaatt tgtccacgtt
    15601 ttccagaacc tgaaatatcg ctttttgcaa tattattttc agccatcaat ttcgctgccg
    15661 aaggggcagg aggcattgta ccgcttggcg ttgcactgct cgaaggagac tgctccaatt
    15721 cagatggtgc ttctggaata aatgtagcag aaggtgaaaa tgattgggaa ataccagctg
    15781 ctccagattc aacaaatcct aaaacagcat tcacttcaac tatatcacct tcctttgcaa
    15841 tgatctcagt taattttccc ataacaggtg aaggaacctc aacggttacc ttatcagttt
    15901 ctaattcaac caagggttca tctacagcta cagcttcgcc aagcttttta aaccacttac
    15961 caattgtcgc ttcggtaact gattcaccca aagtaggaac acggattcca gtagtcataa
    16021 tatttttcca tacatcagag taattaaatt taagaactta acgcatcttc aagaaatgcg
    16081 gaaagttgtt caagatgttt caccatcaac ccagtggccg gtgatgcact cgcaggacgc
    16141 ccaacataac gagcacgtga atattgggca ttaatatgcg tcaaaaccca ttccaaataa
    16201 ggttcaataa acgaccatgc ccccatgttt tttggctctt cttggcacca aacaatctct
    16261 gcctgtaaga agcgagacaa tacatccacc aaagctttcg caggaaaagg ataaagttgc
    16321 tcaatacgca acaaataaac atcattaatt cccctctttt cacgctcttc ataaaggtcg
    16381 taataaacct tacccgtaca aagaacaatg cggcgaattt tgttgtcttt ttgcaattta
    16441 actacagagt ttttaagaag ttccgcacca tcaagcaata aacgatgaaa acgtgtctct
    16501 ggtcccattt cattgaggaa agaaacagcc cgtttatgac gtaaaagcga cttcggtgtc
    16561 atcaaaatta aaggtttacg aaaatcacgt ttaatctgtc gacgcaaaat atgaaaataa
    16621 tttgcaggcg ttgtacaatt cgcaacctgc atattgtctt ccgcacaaag ttgaaggaaa
    16681 cgttccaaac gtgccgaaga atgctccggt ccttgccctt caaaaccatg aggtaataaa
    16741 cacacaagac cagacatacg gagccactta cgctctgcag aagaaataaa ttggtcaaaa
    16801 ataacctgtg caccattaga gaaatcacca aactgcgctt cccaaagtgt taatccgtgc
    16861 ggttcagcaa gagaatatcc atattcaaaa ccaaggacag cttcttcaga aagcatagaa
    16921 ttgacaactt cataaattcc ctgtcccttt tgcaaattat tcaaagggat ataacgtgcc
    16981 tcattttctt gatcataaag aactgaatga cgttgcgaaa aggttccacg ttcaacatcc
    17041 tcaccggaaa gacgaactga tgctccctct aagcaaagcg aaccaaaagc taaagcttca
    17101 gccgttgccc aatcaacgcc ttcaccggtt tcaaaaacct tagcacgatt acttaaaaaa
    17161 cgctgaatag ttttatgaac atgaaaattg ggaggaatct cgacaagttt ctgaccaatt
    17221 tcctttaaag tcttcaatgc cacaccagtc gttccaaagt attgctcttc agtattactg
    17281 gaagctttaa gccccgtcca actcccatca agccaatcag ctttactggg tttataagag
    17341 gtactcgctt caaactcagc ctcaagctta tcacgccaca gctttttttg ctgctcaatc
    17401 tcttctaaag aaatcacgcc ttcttttacc aactggtcac cataaagctg aagagtcgtt
    17461 ttgtgattac ggatcgcctt atacataagc ggttgtgtaa aagaaggttc atcgccttca
    17521 ttatgtccat aacggcgata acaaaacata tcaatcacca ccggtttatg aaaaatttga
    17581 cgaaattccg ttgctatttt tgcaataaaa acaacagctt caggatcatc accattcaca
    17641 tgaaaaatgg gcgcatcgat catttttgcc acatccgatg gataaggtga agagcgcgaa
    17701 aaacggggat cggttgtaaa tccaatttga ttattgacaa taacatgaat agagccggca
    17761 acccggtaac cttttaaacc tgaaagacca aaagtttctt gaatcacacc ttgacctgca
    17821 aaagcagcat caccatgaat gagcagaggt aaaacttttg cgcgctcgct caatgaaata
    17881 acctcagtac gcgcggtgcc aacaagctga tcttgtttag cacgtgtttt tccaataaca
    17941 accggattaa caatctcaag gtgagatgga ttagctaaca acgataaatg aagttttttt
    18001 ccatcaaact caagatcagc tgaagttcct aagtgatatt ttacatcacc ggatccctct
    18061 acatcatcag gcttataaga ccctcctttg aattcatgaa aaatagcctg atgtggctta
    18121 gcgagaactt gtgaaaggac atttaaacga ccacgatgag ccattcctaa aacaacttcc
    18181 tgcacaccca aagtactccc atacttaata atttgttcaa gagcaggaat cagtgcttca
    18241 ccaccatcaa tgccaaaccg ctttgttcct ttatatttta tatctaaaaa ctgttcaaac
    18301 ccttccgcct caatcagctt gttaaggata gctttctttt ctttcggtgt gaaagaaatt
    18361 cgattatctg gtccttcaat acgttcttga agccatgctt tttgagcagg atcagaaata
    18421 tgcatatact ccacaccaat tgttgaacaa taagtgcgat taagaatttc aagcatctgc
    18481 ggaatagttg catattccaa ccctaaaaca ttatcaataa aaatggaacg ctcataatca
    18541 gcagaggtaa aaccgtaagc ttctggagag agttctttgt aatcttccag cttttctgcc
    18601 aattgaagag gatcgagccg tgcatgaaga tgcccacgtg ctcgaaaagc atgaatcatc
    18661 atgagggcat gaacagaatc acgtgttgct tggataatat cttgtttact agaagtcttt
    18721 cccttttgtg taacaccagt ggctattttt tcctttaatt taccgctaag atgtttttca
    18781 agagcaaacc aatcaccatc gagagcagaa accaactctc cactttcctt taacggccag
    18841 tgttcacgtc gccatgtcgc gccttgagca tttttgagaa catcttcttt gttatcttgc
    18901 agagtttcaa aaaaagcacg ccactgtgaa tctacactag agggattttt ttcatattcg
    18961 gcataaagtt gatctatata attggcattt ccaccataaa gaaatgacgt ttgtgcaaaa
    19021 agactgttta tttcgtcttg ccttgccata tacttctccg gaacatttat tccgtctcct
    19081 tatatatcct ctcgaccttt aagtgcttaa aaagcaaatg cagatcggaa aattcaaaaa
    19141 agttccactt tttatatcca atgttccacc tggataagga tatatcctta tccagataaa
    19201 attttctctt atcctctcaa aagcaccatc aaggttttac ctatctgtga tggtgaagga
    19261 gagacgtgaa tgcctgccga ttccattgca gcgattttat cttcggcccc acctttacca
    19321 ccagaaataa cggcaccagc atgacccatt gtacgtcccg gaggagctgt acgaccagca
    19381 ataaaaccga ctataggctt tttacgacct ttttttgctt catctttaag aaactgtgcc
    19441 gcttcttctt cagcagagcc accaatttca ccgatcatga caatagattc ggtttcatca
    19501 tcagccaaaa acagttctaa cacatcaata aattcagtac ccttaacagg atcgccacca
    19561 ataccgatag cggttgtctg ccccaagccc tcctgactgg tttgaaacac ggcttcataa
    19621 gttaaggttc ctgaccgtga aacaacccca acagatcctt ttctaaaaat agaaccaggc
    19681 ataataccga ttttacacgc atgtggcgtg agaataccag gacagttcgg accaattaag
    19741 cgcgattttg attgctctaa tttaacctta accttaacca tatccataac cggtatacct
    19801 tctgtaatac agacaattaa accgatttcc gcttcaatgg cttctattat ggcatctgcg
    19861 gcccctgaag gaggaacata aataacggaa gcatcagctc ctgtcctttc tttcccttcc
    19921 gcaacactgg caaaaatagg aagagattcg cctcttgatc cttcccatac ttcacctcct
    19981 tttttgggat ggacgcctcc aaccattttt gtaccataat aagccagtgc ctgttctgtg
    20041 tgaaaagtcc ctgttttccc tgtaagtcct tgaaccagaa cttttgtatt ctgatgaata
    20101 agaatagaca tggcttaagc tcctctcact gctgcaatga ttttctgagc agcatcgtct
    20161 aaatcactag cagaaacaac attcaaacca ctgtcactta taatcgcttt accctgttca
    20221 atgttcgtac cttcaaggcg aacaaccaaa ggaaccttta aaccaacttc tctcacagca
    20281 gcaacaacac cttcagcaat gacatcgcaa cgcataatac caccaaaaat attgaccaaa
    20341 atgcctttaa catttggatc agcagtaata atcttaaaag cagctgttac tttctctttt
    20401 gaagcaccgc caccaacatc aagaaaattc gcaggctcag ctccatagag cttgataata
    20461 tccattgttg ccatcgcgag acctgcacca tttaccatgc aaccaattgt accctcaaga
    20521 gcaacataag caagatcatg ctttgatgct tcaatctctt ttgggtcttc ttctgaaaga
    20581 tcacgcaatt ctaaaatgtc tggatgacgg aacaaagcat tattgtcaaa agaaactttc
    20641 gcatcaagaa cacgcaaatg accatctttc atcacaataa gtggattaat ttcaaggaga
    20701 ctcatatctt tttcacaaaa cgccttatag agaattggaa aaagtttttc accatctttc
    20761 cttccgttat cgtgcaattc caatgcatca caaagccttt tacaatcagc agaagtaact
    20821 ccttgaacag gatcaacagg cagagttaat attttctctg gtgtctcctc agcaactgtt
    20881 tcaatatcca ttcccccttc catcgaaaca acgaaagcca ctcgaccaac cgcacgatca
    20941 accaaaagtg aaagataaag ctcccgttcg atatcagcac catcctcaat ataaagacga
    21001 ttgacctgct taccctctgg accagtttgt ttagttacca aagttttacc aagcatttct
    21061 tttacatttg caacaacttc ttcaaccgat tttgcaagcc gaacaccacc ctttgaatca
    21121 agatcaagtt ctttaaactt tcctttacca cgaccaccag cgtgaatctg acttttaact
    21181 acataaagtg gcccaggcaa tttttttgcc catttttcag cttgctctac agaataaaca
    21241 gcgacaccat ttgcaattgg tgctccatac tcatgaagca gacgtttagc ctgatactca
    21301 tggatattca ttcacttgtc cttttctttt acggatcact taattgatcc tcaaatcgtc
    21361 ataacatttt aaatattctg ttttcatgaa cagaatctcg tttaatctat ttgagacaag
    21421 gtgcaatagc gatacaagct tcacaaagtt tttttaccgc atttactgat tgctcaaaag
    21481 cacttctttc ctttttatca agatcgattt caatgacccg ctcaacgccg cccgcaccaa
    21541 ggacaacagg aacaccaaca tatgtgtctt tgacaccata ttcacctgaa agataggctg
    21601 caacaggaac aacacgctta atatccttca aataagcttc agccatagaa atagcagagg
    21661 ctgcaggtgc ataaaaagca gaaccagttt ttaacaaacc gacaatttcc gcaccaccat
    21721 tacggacacg ttggataatt tgatcaatct tttcttgtgt cgtccagccc attttcacaa
    21781 gatcgggcaa agaaatacca ccaactgttg aataacgcac caaaggcacc attgaatcgc
    21841 cgtgtcctcc taaaacaaac gctgtcacgt ctttaacaga gaccttaaat tccttagata
    21901 agaaataacg aaaacgtgcc gaatcaagaa caccagccat accaactact ttttgtttgg
    21961 gaagacctga aaatttttgc aatgcccata ccattgcatc aagagggttc gtaatacaaa
    22021 taacgaatgc tgaagatgcg tattttttaa tcccaacacc aacttgttcc atcactttca
    22081 aattaatgcc cagaagatca tcacggctca taccaggttt tcgtgcaacg cctgccgtta
    22141 caatcacaac atcagcacct tcaattgcct cataaacatt agcacctgtt aaactcacat
    22201 caaaaccatc aactggtgaa gattcggcaa tatcaagagc cttaccttgt ggcatgcctt
    22261 cttcaatatc aaataagaca acatcaccaa gttctttaag ccctatcata tgtgctaacg
    22321 tacccccaat catacccgaa ccaatgagag ctattttctt tcgtgccatt ttactttttt
    22381 cctaacgtta gataat
//
