LOCUS       NZ_LN831027.1          24751 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_LN831027.1 Fusobacterium polymorphum strain NCTC10562 chromosome
            1, complete sequence.
ACCESSION   NZ_LN831027
VERSION     NZ_LN831027.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:41:54
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1021022
            Orig. end    :: 1045773
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24751
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[1031022:1035773]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [Aldedh, HAD, HAD_2, IDH, Ldh_1_C, Ldh_1_N,
                     Succ_CoA_lig]) and not (PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene or
                     Gly_radical or Gly_430_pcre or Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_lactate_related"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14751
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [Aldedh, HAD, HAD_2, IDH, Ldh_1_C, Ldh_1_N,
                     Succ_CoA_lig]) and not (PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene or
                     Gly_radical or Gly_430_pcre or Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_lactate_related"
                     /protocluster_number="1"
     cand_cluster    1..24751
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [Aldedh, HAD, HAD_2, IDH, Ldh_1_C, Ldh_1_N,
                     Succ_CoA_lig]) and not (PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene or
                     Gly_radical or Gly_430_pcre or Gly_8-9_TMA))"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="chemical_hybrid"
                     /product="OD_lactate_related"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="gutsmash"
     region          1..24751
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="OD_lactate_related"
                     /product="PFOR_II_pathway"
                     /region_number="4"
                     /rules="(minimum(1, [PFOR_II, POR, POR_N]) and minimum(2,
                     [Aldedh, HAD, HAD_2, IDH, Ldh_1_C, Ldh_1_N, Succ_CoA_lig])
                     and not (PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene or
                     Gly_radical or Gly_430_pcre or Gly_8-9_TMA))"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             710..3148
                     /locus_tag="ctg1_973"
                     /transl_table=11
                     /translation="MLDEELLKKYKAKPDKSIFEHNQDLKKQKDVLINLGYLNNKEKIE
                     LLSYAIDYHDSGKINFKFQKRIEENIKRLNGEKYNPKYLKFDKENEIEHNILSAFLINS
                     QDFNSEDEYLSVLYSVVFHHRYSDAISTINNQIFPNIEEILEDNLPKGVVTYEGDIPLE
                     LNFQDLNTVENIKLLGLLIKCDHSASGGYEIEYPNDFLEDALNNLLNEFKEKDKSADWN
                     NMQKFCKENSDKNIIAIADTGMGKTEGGFLWGGNNKIFFVLPLRTAINAMYKRFDEVII
                     KGENKEERVGLLHSNSLEYYLNNKKELVIDDKDEKEMDILEYNKRGKHLSLPITICTPD
                     QIFNFILKYKGYESKLATLSYSKIILDEMQMYDASLLAAVIFGITKIIEMGGKIAIVTA
                     TFPPIIEYFLNKYLMKDNKNVIKDLDKPEEIVEEPIFIKKKFTNNEKIRHNIVLIDDEI
                     GMEHILWQFKKNKKENKKSNKILVICNTIKKAQEIYLKLKEEDDLKDKINMLHSNFIRE
                     DREEKEKNILDFGKTEFDGEGIWISTSLVEASLDIDFDYLFTELQDLNSLFQRFGRCNR
                     KGKKSVDEANCFIYLKIEDKYLKEKGSKYGFIDKDIYENSKKGLENYCKVISKDEIENS
                     QDYSELLKNYSKKITEGDKIKLIEENLSFENLKESNFVDEFEKTYEKYQRILNSDENSQ
                     DDLKLRDIQSVTVIPYNIYEENKENIKELIKKIEDKNLSLEERQKAKTELLKKTLSIQY
                     YQLSKYISEILKGKADANKYKSESINKFEKITVMEADYDKELGFRAKDFKDGIPTYEFI
                     "
     protocluster    710..23567
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[1031022:1034598](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="2"
                     /tool="gutsmash"
     proto_core      10001..13576
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="2"
     CDS             3218..3712
                     /locus_tag="ctg1_974"
                     /transl_table=11
                     /translation="MDKDITGLMVYYYEVCKRKLWYFVNEIQLEENNSNVILGKLLEEN
                     TYTRDEKKINIDGIINIDFIRSKKILHEIKKSNSIEPASLLQVQYYLYYLEKKGLIGLK
                     GILDYPLLKQTVEVNLTDKDRENLDNIIIGIKEILRKESPPALEKNGICKKCAYFDLCF
                     V"
     CDS             3724..4716
                     /locus_tag="ctg1_975"
                     /transl_table=11
                     /translation="MKRSFFLYSNGTLKRKDNTITFINEKDEKRDIPIEMVDDFYVMSE
                     MNFNTKFINYISQFGIPIHFFNYYTFYTGSFYPREMNISGQLLVKQVEHYTNEQKRVEI
                     AREFIEGASFNIYRNLRYYNGRGKDLKFYMDQIEELRKHLKEVNNVEELMGYEGNIRKI
                     YYEAWNIIVNQEIDFEKRVKNPPDNMINSLISFINTLFYTKVLGEIYKTQLNPTVSYLH
                     QPSTRRFSLSLDISEVFKPLIVDRLIFSLLNKNQITEKSFVKDFEYLRLKEDVSKLIVQ
                     EFEDRLKQIITHKDLNRKISYQYLVRLECYKLIKHLLGEKKYKSFQMWW"
     CDS             4721..4999
                     /locus_tag="ctg1_976"
                     /transl_table=11
                     /translation="MYVVAVYDISLDEKGSHNWRKIFGICKRYLHHIQNSVFEGELSEV
                     DIQRLKYEVSKYIRDDLDSFIIFKSRNEKWMEKEMLGLQEDKTDNFL"
     CDS             7587..8591
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTA_PTB"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_977"
                     /sec_met_domain="PTA_PTB (E-value: 2e-120, bitscore: 399.0,
                     seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFLGQVRKKALQANRRIVLPETSDERVIRAAAQILKEGLAQIIL
                     VGNQETIMHSAKAYEVSLSGAKIVDPYNFERLNDYVNKLVELRSKKGMTAEEAKKILLN
                     DPNFFGAMLIKMGDADGMVSGSASPTANVLRAAIQVIGTQPGVKTVSSVFIMELSQFKD
                     LFGSILVFGDCSVIPFPTSEQLADIATSAAETAVKIAGINPRVALLTFSTKGSAKHECV
                     DRVIEAGRILRERKVPFRFDDELQADAALVKSVGEIKAPLSDVSGNANVLIFPTLSAGN
                     IGYKLVQRLAGANAYGPIIQGLNAPVNDLSRGCSVEDIVVLTAITSAQACIDC"
     CDS             8659..9855
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetate_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_978"
                     /sec_met_domain="Acetate_kinase (E-value: 2.5e-149,
                     bitscore: 494.3, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKILVINCGSSSLKYQLINPETEEVFAKGLCERIGIDGSKMEYEV
                     VAKDFEKKLETPMPSHKEALELVISHLTDKEIGVIASVDEVDAIGHRVVHGGEEFAQSV
                     LINDAVLKAIEANNDLAPLHNPANLMGIRTCMELMPGKKNVAVFDTAFHQTMKPEAFMY
                     PLPYEDYKELKVRKYGFHGTSHLYVSGIMREIMGNPEHSKIIVCHLGNGASITAVKDGK
                     SIDTSMGLTPLQGLMMGTRCGDIDPAAVLFVKNKRGLTDAQMDDRMNKKSGILGLFGKS
                     SDCRDMETAVKEGDERAILAESVSMHRLRSYIGAYAAVMGGVDAICFTGGIGENSSMTR
                     EKALEGLEFLGVELDKEINSVRKKGNVKLSKETSKVLVYKIPTNEELVIARDTFRLAK"
     CDS             10001..13576
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_lactate_related: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_lactate_related: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_lactate_related: POR_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_979"
                     /sec_met_domain="PFOR_II (E-value: 3.2e-16, bitscore: 56.7,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 2.7e-80, bitscore: 266.5,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 1.5e-31, bitscore: 106.9,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.8e-13, bitscore:
                     47.6, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.8e-10, bitscore: 38.1,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 2.4e-07, bitscore: 27.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.023, bitscore: 12.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 6.6e-21, bitscore: 71.0,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKKMQTMDGNQAAAYASYAFTEVAGIYPITPSSPMAEYTDEWAS
                     RGVKNIFGVPVKLVEMQSEGGAAGTVHGSLQAGALTTTYTASQGLLLKIPNMYKIAGEL
                     LPGVIHVSARSLSAQALSIFGDHQDIYAARQTGFAMFATNSVQEVMDLAGVAHLAALKS
                     RVPFLHFFDGFRTSHEIQKVEVMEYDDLKKLIDWKALEEFRKRALNPEHPVTRGTAQND
                     DIYFQTREVQNKFYDAVPDIVADYMKEISKITGREYKPFNYYGAPDAERIIIAMGSVCE
                     TAQEVIDYLVEKGEKVGLISVHLFRPFSAKYFFDVLPKTVKRISVLDRTKEPGSLGEPL
                     LLDIKALFYNKENAPLIVGGRYGLSSKDTTPAQILAVFENLKKDEPKDAFTVGIVDDVT
                     HTSLEVGPAIALADPSTKACLFYGLGADGTVGANKNSIKIIGDKTDLYAQGYFAYDSKK
                     SGGVTRSHLRFGKKPIRSTYLVSKPTFVACSVPAYLHQYDMTSGLKEGGKFLLNCVWSK
                     EEAIENIPNNVKRDLAVNKARLFIINATALAQEIGLGQRTNTIMQAAFFKLAEIIPFEE
                     AQQYMKDYAKKSYAKKGDEIVQLNYNAIDRGANDIVEIEVDPAWANLEVTPLNEPKETA
                     GCGGCCPTPSDFVKNIVKPINAIKGNDLPVSAFLGYEDGTFENGTSAFEKRGVAVDVPI
                     WDVDKCIQCNQCSYVCPHAAIRPFLINEDELKASPEPLATKKPVGKGLDGLAYRIQVSA
                     LDCVGCGSCAHVCPAPGKALVMRPIAESLEAHEDVKTDYLYNNVDYRSDLMPVDTVKGS
                     QFSKPLFEFHGACPGCGETPYIKLITQLYGDRMMVANATGCSSIYSGSAPSTPYTTNKN
                     GEGPSWGSSLFEDNAEYGFGMHVGVEALRSRIQHAMEENMDKVDEDIATLFKDWIANRQ
                     FSVRTREIRDILVPKLEALNTDFAKEILDLKQYLIKKSQWIIGGDGWAYDIGYGGLDHV
                     LASNEDINILVVDTEVYSNTGGQASKSTPTGAVAKFAAAGKPVKKKDLAAIAMSYGHIY
                     VAQVSMGANQQQALKAIKEAEAHQGPSIIIAYSPCINHGIKKGMSQAQTEMKLATECGY
                     WPIFRYNPSVEKLGKNPLQIDCKEPKWEKYEEYLTGEVRYQTLTKSNPEEAKILFEINK
                     RDAQKRWRQYKRMAALDYSEEKETE"
     CDS             13795..14751
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_lactate_related: Ldh_1_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_lactate_related: Ldh_1_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_980"
                     /sec_met_domain="Ldh_1_C (E-value: 7e-25, bitscore: 85.0,
                     seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Ldh_1_N (E-value: 3.6e-26, bitscore: 89.1,
                     seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLQTRKVGIVGVGHVGSHCALSMLLQGVSDEMVLMDIIPEKAKAH
                     AIDCMDTISFLPHRAIISDGGIQELSKMDVIVISVGSLTKNEQRLEELKGSLEAIKSFV
                     PDVVKAGFNGIFVTITNPVDIVTYFVRELSGFPKNKVIGTGTGLDSARLKRILSEVTNI
                     DSQVIQAYMLGEHGDTQVANFSSATIQGVPFLGYMKSHPEQFKGIELSVLEKQVVRTAW
                     DIISGKNCTEFGIGCTCSNLVKAIFHNERRVLPCSAYLDGEYGYSGFYTGVPAIIGSNG
                     IEEILELPLDERERKGFEAACAVMKKYIEIGKSYKIV"
     CDS             14772..15986
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 67.9; E-value: 2.5e-21)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_981"
                     /sec_met_domain="MFS_1 (E-value: 9.3e-20, bitscore: 67.9,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VQSKESNIKLLLLGRAVSLFGSTIYLIVLPLYILNTTKNLKTTGI
                     FFAAVNFPTIIVSIFIGTIIEKFNKKNIILICDFLTSMLYFVLFLYLKNFNSLSFLFLI
                     SLLINIVSKFFEIASKVLFSEINSPETLEKYNGLQSFMENTIIIVGPVIGTYLFVTFDF
                     NLILIIVSLGYFLSFLQELFIKYEKNLNLSIEKTNFLEDFKEGISYIGSNKIILNFFIL
                     VMFLNFFIANNDEIINPGILIRKYEISEKLFGFSATSYGAGSVFAGIFIYYNNKFKFLK
                     KLKLLFILNSSLMCLLGLLSIILFKYNHYIYFIIFIFFQFLIGMITTFVNVPLISSFQK
                     NVEIKYQSRFFSILSFFSGGLIPLGILYAGYLSSYIGADITYIINNLAIITIVCLVFKN
                     IERDC"
     CDS             complement(16022..17041)
                     /locus_tag="ctg1_982"
                     /transl_table=11
                     /translation="MIARTNEGKIDYKKIIIESGLYLVLFCMLIAIIIKEPTFLSIRNF
                     KNILTQSSVRTIIALGVAGLIVTQGTDLSAGRQVGLSAVISGTLLQSMTNVNKAFPTLG
                     EFSIFTTILIVVVVGIVIASINGIVVATLNVHPFIATMGTMTIVYGINSLYYDKAGAAP
                     ISGFVEKYSKFAQGYIQIGSYTIPYLIIYAAIATLIMWVLWNKTKFGKNVFAVGGNPEA
                     AKVSGVNVVLTLIGIYALSGAYYAFGGFLEAGRIGSATNNLGFMYEMDAIAACVIGGVS
                     FYGGVGRISGVITGVIILTIINYGLTYTGVSPYWQYIIKGIIIVTAVAFDSIKYAKKK"
     CDS             complement(17062..18564)
                     /locus_tag="ctg1_983"
                     /transl_table=11
                     /translation="MENLKYVLEMENISKEFPGVKALDNVQLKLKPGTVHALMGENGAG
                     KSTLMKCLFGIYEKNSGKILLDGVEVNFKSTKEALENGVSMVHQELNQVLQRNVLDNIW
                     LGRYPMKGFFVDEKKMYNDTINIFKDLDIKVDPRKKVAELPIAERQMIEIAKAVSYKSK
                     VIVMDEPTSSLTEKEVDHLFKIIKKLKESGVGIIYISHKMEEIKMISDEITILRDGKWI
                     STNDVSKISTEQIISMMVGRDLTERFPKKDNTAKEMMLEVKNLTALNQPSIQDVSFELY
                     KGEILGIAGLVGSKRTEIVETIFGMRPKEHGEIILNGKTVKNRNPEEAIKNGFALVTEE
                     RRSTGIFSMLDIAFNSVISNLDRYKNKFKLLKNKDIEKDTKWIVDSMRVKTPSYSTKIG
                     SLSGGNQQKVIIGRWLLTEPEVLMLDEPTRGIDVLAKYEIYQLMIDLAKKDKGIIMISS
                     EMPELLGVTDRILVMSNGRVAGIVKTSETNQEEIMELSAKYL"
     CDS             complement(18655..19680)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_984"
                     /sec_met_domain="Peripla_BP_1 (E-value: 3.2e-08, bitscore:
                     30.4, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKFGMLLGSIILASALVACGEKKEEAKTDAPAAEKLSIGLTAYK
                     FDDNFIALFRKAFEAEAAAKADTVEVTAIDSQNSVATEKEQIEAVLEKGVKAFAINLVD
                     ASAADGIINLLKEKNVPVVFYNRKPSDEAIASYDKLYYVGIDPNAQGIAQGELIEKLWK
                     ENPDLDLNKDGVIQYVMLTGEPGHPDAVARTKYSISTLNDHGIKTEELHQDTAMWDTAT
                     AKDKMDAWLSGPNGSKIEVVICNNDGMALGAIESMKAAGKVLPTFGVDALPEALVKIEA
                     GEMAGTVLNDAKGQASATFNMVVNLAQGKEPTEGTDLKLDNKIILIPSIGIDKSNVADF
                     K"
     CDS             complement(19877..20824)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ROK"
                     /gene_functions="other (smcogs) SMCOG1034:Repressor, ORF,
                     Kinase (Score: 236.5; E-value: 1.5e-72)"
                     /gene_kind="other"
                     /locus_tag="ctg1_985"
                     /sec_met_domain="ROK (E-value: 5.8e-71, bitscore: 236.5,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHYIGIDLGGTNTKIGIVDSEGNLINSKIIKTHSHQNVDKTLER
                     IWETAKKLILEKEIPLFSVVGIGIGIPGPVKNQSIVGFFANFDWERNLNLKEKMERLSG
                     IETRIENDANIIAQGEAIFGAAKGKKSSITIAIGTGIGGGIFYNGNLISGMSGVGGEIG
                     HMKVVKDGKTCGCGQNGCFEAYASANSLVKEAKERLKLNENNLLFKEINGNLDELEAKN
                     IFDTARKGDEFSKDLIEYESDYLALGIGNLLNIINPECIVISGGISLAGDEILLPVKEK
                     LKKYTMPPALENLEIKVGVLGNEAGIKGAVALFI"
     CDS             complement(20846..21988)
                     /locus_tag="ctg1_986"
                     /transl_table=11
                     /translation="LKKLFKILFYLIIIFIILMIATYLFMKTPAFGALPSGKSLEKVKA
                     SKNYVDGEFKNKESTELLTDTKKTPIKRLLEFAFEKDPEGTVPDFDLPSIKTDLKNLDP
                     SEDVMVWFGHSSLFIQISGKKVLVDPVFSKYASPVPFTNKAFKGTNVYDVDDLPEIDIL
                     LITHDHYDHLDYPTIKKLKNKVAKIIVPLGVDAHLLRWGYDEDKITTVDWDDEVVIDDN
                     LKIYALEARHFSGRSFFNRNQSLWVSYLIEEKINNKNYKLFLSGDGGYSGRFKEFKERF
                     GKIDLAAMESGQYNKEWSLIHSKPEDVLMASQDMEVENLLPIHNSKFKLSNHTWDDPLK
                     RLDELTKNTNIKLLTPIIGEKIYLHKENSFSKWWENIENK"
     CDS             complement(21999..22922)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_987"
                     /sec_met_domain="Pyr_redox_2 (E-value: 7.1e-30, bitscore:
                     101.3, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKIYDVVIVGAGPAGLTAGIYAGRGNLSTLILEKEGIGSMVMTH
                     QIDNYPGSHIGASGKEIYDTMKKQALDFGCEIKPATVLGFDPYEEIKVVKTDAGNFKTK
                     YIIIATGLGKIGAKKIKGENKFLGAGVSYCATCDGAFTKGRVVSLVGKGDELIEESLFL
                     TRYAKEVNVFLTSDDLDCNEELKEAILSKENVKITKKVKLLEIKGEEFVTGLDLEVDGN
                     KETVATDFVFLYLGTKNNLELYGEFVSLSETGYIITDETMKTRTDKMYAIGDIREKDVR
                     QIATATNDGVIATTFILKEILKSKKK"
     CDS             complement(22944..23567)
                     /locus_tag="ctg1_988"
                     /transl_table=11
                     /translation="LRVKCFHLGAYGTNCFLAYNENNIAYFFDCGGRNLDKVYDFISEH
                     NLNLKYIVLTHGHGDHIEGLNDLSSHYPEAKVYIGEEEKDFLYNSELSLSDRIFGEFFK
                     FKGEIHTVKEGDMVGDFKVIDTPGHTIGSKSFYYEKDKILISGDTLFRRSYGRYDLPTG
                     DLEMLCHSLEKLSKLPSDTVVYNGHTDNTTIGEEKLFLARVGIL"
     CDS             complement(23731..24525)
                     /locus_tag="ctg1_989"
                     /transl_table=11
                     /translation="MAEKTQKIGIFDSGLGGTTVLKEMIKSLPNEDYIYYGDNGNFPYG
                     SGKTKNELQKLTERILDFFVKNNCKLVIVACNTASTAAIDYLREKFSLPIIGIVEAGVK
                     IASKTTKNKNIAVISTKFTAESHGYKNKAKMLDSELNVKEIACIEFAQMIESGWDTFDN
                     RKELLNKYLSEIPKNTDTLVLGCTHYPLIRKDIEKNIKIKVVDPAVEIVERATQTLTTL
                     NLLNDKKEKGKVIFFVTGETYHFKPTAEKFLGKEIEIYRIPK"
ORIGIN
        1 aaaaagaaaa aagaagataa aaaatcagaa acttttaaac aactttcaga agaagaaaag
       61 aaaatcaagc ttgatgaaga aaaatacaag gaagatttta aaaaatttga atatgaaaac
      121 tatacaaaac catacagcta ttttcaaaac cttgttactt ctttaaaaag ctatgaagtt
      181 ttaaatgata tttttctaat tttacatata aaatctgatg aaaaaacttt aaaagatata
      241 gaagaaaata tttataactt gcaatcatta ggaagaagtg aagattttgt tgaagttgtt
      301 gaatgtaaaa taattgagtt acaagagttt tcaagaaata ttagagtttc aaaattttct
      361 atgtatttaa aaaataaaga tgtgagtgat aaaaaaataa ttcctttagc agttgatcaa
      421 gatcatcaag caggtggaac aaaatattac ttagataaaa attatagact tgaaaaaaac
      481 agaagaatat ttaaaaaagt tccagttgta tatagtaatt ttgtaggagc taaaaatagt
      541 agtgagaatg taaagctgga ttatttagaa atattgggtc aagacaaaaa acaagagatt
      601 ttggttaatt ttctttaatt aaattatatt attagctagg aaaaataaaa atttcctagc
      661 taattacctt ataaaagaat attattaaaa ttgaggagtg agatataaga tgttagatga
      721 ggaacttctt aaaaaatata aagcaaaacc cgataaaagt atttttgagc ataaccaaga
      781 tttaaaaaaa cagaaagatg ttttaataaa tttaggatat cttaataata aagaaaaaat
      841 agaactttta tcatatgcaa tagattacca cgatagtggg aaaattaatt tcaaatttca
      901 aaaaaggata gaagaaaata taaaaagact taatggagaa aaatataatc ctaaatattt
      961 aaaatttgat aaagaaaatg aaatagaaca taatattctt tcagcttttt taataaattc
     1021 acaagatttt aattcagaag atgaatattt atcagtactt tattcagttg tatttcatca
     1081 tagatattca gatgcaatta gtacaataaa taaccaaatt tttcctaata tagaggagat
     1141 tttagaagat aacttaccaa agggagtagt aacttatgaa ggggatatac cgttagaatt
     1201 gaatttccaa gatttaaata cagtagaaaa tataaaatta ttgggtttac ttataaaatg
     1261 tgaccattca gctagtggag gatatgaaat tgaatatcct aatgattttt tagaagatgc
     1321 tttaaataat ctgctgaatg aatttaaaga aaaagataaa tcagctgatt ggaataatat
     1381 gcaaaaattc tgtaaagaaa atagtgataa aaatataatt gcaatagcag atacaggaat
     1441 gggtaaaact gagggaggtt ttctttgggg aggaaataat aagatatttt ttgttcttcc
     1501 ccttagaact gctattaatg cgatgtataa aagatttgat gaagttataa taaaaggaga
     1561 aaataaagaa gaaagagtag gtttattgca ttcaaattct cttgaatatt atttgaataa
     1621 taaaaaagaa ctagtaattg atgataaaga tgagaaagaa atggatatct tagaatacaa
     1681 taaaagagga aaacatttat ctttacctat aactatctgt acaccagatc agatatttaa
     1741 ctttattcta aaatataaag gttatgaaag taaattagct actctttctt actcaaaaat
     1801 aattttagat gaaatgcaga tgtatgatgc aagtttgctt gcagctgtaa tttttggaat
     1861 tactaaaatt atagaaatgg gaggtaaaat tgctattgta actgctactt ttcctccaat
     1921 aattgaatat tttttgaata aatatttgat gaaagataat aaaaatgtaa taaaagactt
     1981 agataaacca gaagaaattg ttgaagaacc aatatttata aaaaagaaat ttactaataa
     2041 tgaaaaaata agacacaata tagttcttat tgatgatgaa attggaatgg agcatatttt
     2101 atggcaattt aaaaaaaata aaaaagagaa taaaaagtct aataaaattt tagttatctg
     2161 taacactata aaaaaagcac aagaaatcta tttaaaatta aaagaagaag atgatttgaa
     2221 agataaaatt aatatgttac attcaaactt tattcgtgag gatagagaag aaaaagaaaa
     2281 aaatatttta gattttggaa aaactgaatt tgatggtgaa ggaatttgga tatcaacttc
     2341 acttgttgaa gcctcactag atattgattt tgactattta tttacagagt tacaagattt
     2401 aaattcatta ttccaaaggt tcggaagatg taatcgtaaa ggcaaaaaat cagtagatga
     2461 agctaattgt tttatatatt taaaaattga agacaaatat ttaaaagaaa aggggtctaa
     2521 atatggtttc atagataagg atatttacga aaattcaaaa aaaggcttag aaaattattg
     2581 taaagtaata tcaaaagatg aaatagaaaa ttctcaagat tatagcgaat tacttaaaaa
     2641 ttattcaaaa aaaattacag aaggagataa aattaaatta atagaagaaa atttaagttt
     2701 tgaaaattta aaagaaagta attttgttga tgaatttgaa aaaacttatg aaaaatacca
     2761 aagaatttta aatagtgatg aaaattcaca agatgattta aaacttaggg atatccaaag
     2821 tgttactgta attccataca atatttatga ggaaaataaa gaaaatataa aggaacttat
     2881 aaaaaagata gaggataaaa atttaagttt agaagaaaga caaaaggcta aaactgagct
     2941 tttaaagaaa actctttcaa ttcaatatta tcaattaagt aaatatataa gtgaaatttt
     3001 aaaaggtaaa gctgatgcaa ataaatataa atcagaaagt attaataaat ttgaaaaaat
     3061 aactgttatg gaagcagatt atgataagga attaggtttc cgtgcaaaag attttaaaga
     3121 tggtattcca acttatgaat ttatttaatt aattcaaaat aattttaact acacaaaagt
     3181 ggaactttat caattaaact atggggagat agatactatg gataaggata taactggatt
     3241 gatggtttat tattatgaag tctgtaaaag aaagttatgg tattttgtaa atgaaattca
     3301 acttgaagaa aataattcaa atgttatttt aggaaaactt ttagaagaaa atacttatac
     3361 cagagatgag aagaaaatta atatagatgg gattataaat attgatttta ttcgctcaaa
     3421 aaagatattg cacgaaatta agaaaagtaa ttcaatagag ccagcttctt tgctacaagt
     3481 ccaatattat ttgtattatt tagagaaaaa aggattaatt ggattaaaag gaattttgga
     3541 ttatccatta ttgaagcaaa cagttgaagt taatttaaca gataaagaca gagaaaattt
     3601 agataatata ataataggaa taaaagaaat tttaaggaaa gaaagtcctc cagcattaga
     3661 gaaaaatggt atttgtaaaa aatgtgctta ttttgattta tgttttgtat aggagggctt
     3721 agtatgaaaa gaagtttctt tctttatagt aatggtacat tgaaaagaaa agataatact
     3781 ataacattta taaatgaaaa agatgaaaaa agagatattc ctattgaaat ggtagatgat
     3841 ttttatgtta tgtctgaaat gaattttaat actaaattta ttaactacat atcacaattt
     3901 ggtattccaa tacatttttt taattattat actttttaca caggaagttt ttatccaaga
     3961 gaaatgaata tttcaggaca acttttagta aaacaagttg aacattacac aaatgaacaa
     4021 aaaagagttg agatagctag ggaatttata gaaggtgctt catttaatat ctatcgtaat
     4081 ttaagatact ataatggtag aggaaaagat ttaaaattct atatggatca aatagaagaa
     4141 cttagaaagc atttaaaaga agttaataat gttgaagaat taatgggata tgaaggaaac
     4201 attagaaaaa tttattacga ggcttggaat attattgtaa atcaagaaat agattttgaa
     4261 aaaagagtta aaaatcctcc tgataatatg attaattctt taatctcatt tataaatact
     4321 cttttttata caaaggtatt aggagaaatt tataagacac aactaaatcc aacagttagt
     4381 tacttacatc aacctagtac aagaagattt tccctttcac ttgatatttc agaagtattt
     4441 aaaccactga tagttgatag attgattttt tcattattaa ataaaaatca aattacagag
     4501 aaaagttttg tgaaagattt tgaatattta agattaaaag aagatgtctc taaacttatt
     4561 gttcaagaat ttgaagatag attaaaacaa ataataactc ataaggactt aaatagaaaa
     4621 atatcttatc aatatttagt gagactagaa tgttacaaac tcattaaaca tttattaggt
     4681 gaaaagaaat ataaatcttt tcaaatgtgg tggtgataaa atgtatgtag ttgcagtgta
     4741 tgatatttca ttggatgaaa aaggtagtca taattggaga aaaatttttg gaatttgtaa
     4801 aagatatctt catcatattc aaaattctgt ctttgaagga gaattatcag aagttgatat
     4861 tcaaagatta aaatatgaag tttcaaaata tattagagat gatttagatt cttttataat
     4921 ttttaaatca agaaatgaaa aatggatgga aaaggaaatg ctaggtttac aagaagataa
     4981 aactgataat ttcttataaa atttattgtc tacctctcat aatgtaaaat tactggaaga
     5041 ttgacaaaag tcaaaaaagt ctttatttat aaataaattt aagaaaataa aaaaaattta
     5101 agaaattaaa tttttttatt ttttactaaa aaacttatat tgacaaaaag atattaaaaa
     5161 agtattatat gggagtagtt tttttaggta gctatttatg tatttctata ttagaattta
     5221 aataaggctt gaacacagat taactaagaa aattataaaa aatttatgta tttctatatt
     5281 agaatttaaa tggagagata gtattgacac attaggagtt gaggtaattt atgtatttct
     5341 atattagaat ttaaataaat ggtatttgta aagttgattt ctttatactc ttaatttatg
     5401 tatttctata ttagaattta aatcaacttt aaaaattatt ggatgtaagg agttgtattc
     5461 atttatgtat ttctatatta gaatttaaat tctaatgcta aactgttctt ttttaatgga
     5521 tttattcatt tatgtatttc tatattagaa tttaaatgat aaagctttaa ttttaacagc
     5581 aggagtagac atcatttatg tatttctata ttagaattta aatatagctg attgttgagc
     5641 aagtaactct ttttcttttc atttatgtat ttctatatta gaatttaaat actttcttgg
     5701 actcagttac aacaaactct attttaaatt tatgtatttc tatattagaa tttaaatttc
     5761 ttaaaaaata attcagtcaa aaaatttctt tttacattta tgtatttcta tattagaatt
     5821 taaattttta tatctttttt gcttacttgg attcttttct ttatttatgt atttctatat
     5881 tagaatttaa atctggtgat ggaataacta aaattgtagc ttttaagatt tatgtatttc
     5941 tatattagaa tttaaattaa ataaaaataa gcaacaagaa aattaaatct ttatttatgt
     6001 atttctatat tagaatttaa atacaattaa aaaaatgttt agactactgc aaagagaaag
     6061 atttatgtat ttctatatta gaatttaaat attgcagctg aggtagtgga taagtctata
     6121 tttaaattta tgtatttcta tattagaatt taaatgctct tattttttct tcttttgtca
     6181 tttctctcaa tttatgtatt tctatattag aatttaaatt tgctattaaa tatttctaag
     6241 cccttgcttt ttccatttat gtatttctat attagaattt aaataaatat acgcctaaac
     6301 tctccatttt tccacctttt atttatgtat ttctatatta gaatttaaat ggtttatata
     6361 atgtttcttc gactcttata ttttcaattt atgtatttct atattagaat ttaaatagct
     6421 tagaaagcga acttcatatt caactgattg gatttatgta tttctatatt agaatttaaa
     6481 tcttaattga tttactctct ctttttcatt gatttttaat ttatgtattt ctatattaga
     6541 atttaaatat aaatatatga attgggtgta tcaagatata gcaaatttat gtatttctat
     6601 attagaattt aaatgtaata atgtgttttg taatatcatc aaatgtagaa atttatgtat
     6661 ttctatatta gaatttaaat cccttataag tagcaaattc ttttgtaaaa ctttctattt
     6721 atgtatttct atattagaat ttaaataaga tagataaaat gttggaatta gtaactcaaa
     6781 gaatttatgt atttctatat tagaatttaa ataatggaac aatatcagga aggagagtaa
     6841 gtaaggaatt tatgtatttc tatattagaa tttaaatagt tctgttgcag cttttatctt
     6901 tgcataatca cttaatttat gtatttctat attagaattt aaatggaact gctgctttag
     6961 gtgttaaact tccttcataa atttatgtat ttctatatta gaatttaaat gttttatata
     7021 gtgagtttga gagagagttg actgaaattt atgtatttct atattagaat ttaaagtgaa
     7081 tttctttaaa atttaatgta taattcaagt atcaatttat gtatttctat attagaaaaa
     7141 aatacagaag aaagggattg aaaaataaag acttaatgct gttatataac aaaagaataa
     7201 ataaaaaatt aaaaggatta actctagttt tttatataag ttaatccttt ttaataagtt
     7261 aaattaaatt tattcaattt tttaagggga gtacattttt tattatgtta agtatagctt
     7321 tataaagtaa actaagaatt aagtattcat aaagtaacag aaaaattaaa aaaacgaaat
     7381 tcaactaaaa tattaatata atgaacacaa aaatttaaga tagaaaataa aaattatcaa
     7441 ttattaaatt aataaaattt tattaaaaat taagtgaatt tcacaataaa aatattgcat
     7501 ttaatcgtaa ttggtgttaa tatatactta ataaatttga aagataaatt taaagtttta
     7561 tctactaaaa atagggagtg attataatga gttttttagg gcaagttaga aaaaaagcct
     7621 tacaagcaaa cagaagaata gttttacctg aaacaagtga tgaaagagta attagagcag
     7681 ctgcacaaat attgaaagaa gggctggctc aaattattct tgtgggaaat caagaaacaa
     7741 taatgcatag tgcaaaggct tatgaagttt cattaagtgg agctaaaatt gttgatccat
     7801 ataattttga aagattgaat gactatgtta ataaactagt tgaactaaga tctaaaaaag
     7861 gaatgacagc agaagaagca aaaaaaatat tattaaatga tcctaatttt tttggagcta
     7921 tgttaataaa aatgggagat gctgatggaa tggtatctgg ttctgcatca ccaactgcaa
     7981 atgtattaag ggctgctata caagttatag gaactcaacc aggagtaaaa acagtttcat
     8041 ctgttttcat aatggaatta tctcaattta aagatttatt tggaagtatt ttagtatttg
     8101 gagattgttc agttatacct tttccaacat ctgaacaact agcagatatt gctacctcag
     8161 cagctgaaac agcagtaaaa atagctggaa taaatccaag agtagcattg ttgacattct
     8221 ctacaaaagg ttcagcaaaa catgaatgtg ttgatagagt aattgaagca ggaagaattt
     8281 taagagaaag aaaagttcca tttagatttg atgatgaatt acaagcagat gctgccttag
     8341 taaaatctgt tggagaaatt aaagctcctt tatcagatgt atcaggaaat gcaaatgtat
     8401 taatattccc tacattatct gctggaaata ttggatataa attagttcaa agattagcag
     8461 gagctaatgc ttacggacca attattcaag gattaaatgc accagtaaat gatttatcaa
     8521 gaggttgctc agttgaagat atagttgtat taacagctat tacatctgct caagcttgta
     8581 tagattgtta atattgatta gctataaact aaaataatta taataattat ataatacaac
     8641 agatggagga aaagataaat gaaaatacta gtaattaatt gtggaagctc ttcactaaaa
     8701 taccaattaa taaatccaga gactgaagaa gtttttgcaa aaggactttg tgaaagaatt
     8761 ggaatagatg gttctaagat ggaatacgaa gttgtagcaa aagattttga aaaaaaatta
     8821 gaaactccta tgccaagcca caaagaagca ttagaattag taatatctca tttaactgat
     8881 aaagaaatag gggttatagc ctctgttgat gaagttgatg caatagggca cagagtagta
     8941 catggaggag aagaatttgc acaatcagtt ttaataaatg atgcagtttt aaaagctatt
     9001 gaagcaaata atgatttagc acctttacat aatccagcaa acttaatggg aataagaact
     9061 tgtatggaac ttatgcctgg aaagaaaaat gttgctgtgt ttgatactgc tttccatcaa
     9121 actatgaaac cagaagcatt tatgtatcca ttaccatatg aagattacaa agaattaaaa
     9181 gttagaaaat atggtttcca tggaacatct cacttatatg tatctggaat tatgagagaa
     9241 attatgggaa atcctgaaca ttcaaaaata atagtttgtc acttaggaaa tggagcatca
     9301 ataactgctg ttaaggatgg gaaatcaatt gatacttcaa tggggttaac tcctctacaa
     9361 ggtttaatga tgggaacaag atgtggagat atagatccag cagctgtact atttgttaaa
     9421 aacaaaagag gacttacaga tgctcaaatg gatgatagaa tgaataaaaa atctggaatt
     9481 cttggattgt ttggaaaatc ttctgattgt agagatatgg aaactgcagt taaagaagga
     9541 gatgaaagag caatacttgc tgaaagtgtt tctatgcata gattaagatc atatataggg
     9601 gcttatgctg ctgttatggg tggagtagat gctatctgct ttacaggagg aataggagaa
     9661 aattcttcta tgactaggga aaaagcatta gaaggtttag aatttttagg agttgaatta
     9721 gataaagaga ttaactcagt tagaaaaaag ggaaatgtaa aattatctaa ggaaacttcg
     9781 aaagttttag tgtataaaat acctactaat gaagaattag taatagctag agatactttt
     9841 agactagcaa aataatagtt tatataatta aaaaaaatat aaataattaa taatattaaa
     9901 acacttatga ttttgatttc gataatcata aagttttata taaaatagtg aaatgataga
     9961 aattaaacaa gtaaaaaatt agaaattagg aggaaactat atggcaaaaa aaatgcaaac
    10021 tatggatgga aaccaagcag cagcttatgc atcttatgcc tttacagaag tggcaggaat
    10081 ttatcctata actccatctt caccaatggc agaatataca gatgaatggg catcaagagg
    10141 agttaaaaat atttttggtg ttccagtaaa attagttgaa atgcaatcag aaggaggagc
    10201 agcaggaact gttcatggat ctttacaagc aggagcatta acaactactt atactgcatc
    10261 acaaggatta cttttaaaaa ttcctaatat gtataaaata gctggagaat tattaccagg
    10321 agttatacat gtatctgcaa gatctttatc tgcacaagca ttatcaattt ttggtgacca
    10381 ccaagatatt tatgcagcaa gacaaacagg ttttgcaatg tttgctacaa actctgttca
    10441 agaagttatg gacttagcag gagtagctca cttagcagct ttaaaatcaa gagttccttt
    10501 cttacacttc tttgatggat ttagaacttc tcatgaaatt caaaaagttg aagtaatgga
    10561 atatgatgat ttaaagaaat taatagactg gaaagcttta gaagaattta gaaaaagagc
    10621 tttaaatcca gaacatccag taacaagagg tactgcacaa aatgatgata tttacttcca
    10681 aacaagagaa gtacaaaata aattctatga tgcagttcct gatatagttg cggactatat
    10741 gaaagaaatt tctaaaataa ctggtagaga atataaacca tttaactact atggtgctcc
    10801 agacgctgaa agaattataa ttgcaatggg atcagtttgt gaaacagcac aagaagttat
    10861 agattactta gtagaaaaag gagaaaaagt aggtttaata tctgtacact tatttagacc
    10921 tttctctgct aaatacttct ttgatgtttt accaaaaact gtaaaaagaa tttcagtttt
    10981 agatagaaca aaagaaccag gttcattagg agaaccatta ttacttgata ttaaagcatt
    11041 gttctataat aaagaaaatg caccacttat agttggtgga agatatggat tatcttcaaa
    11101 agatacaact ccagctcaaa ttttagctgt atttgaaaat ttaaagaaag atgaaccaaa
    11161 agatgctttc acagttggta tagttgatga tgttactcat acatcattag aagtagggcc
    11221 agcaatagca cttgctgacc catcaacaaa agcttgtcta ttctatggat taggagcaga
    11281 tggaacagtt ggagcaaata aaaactctat taaaatcata ggggataaaa ctgatttata
    11341 tgctcaagga tactttgcat atgactctaa aaaatcagga ggagttacta gatctcactt
    11401 aagatttggt aaaaaaccaa ttagatcaac ttatttagta tctaaaccaa catttgttgc
    11461 ttgttctgta ccagcatatt tacatcaata tgatatgact tctggactta aagaaggagg
    11521 aaaattctta cttaactgtg tatggtctaa agaggaagca atagaaaata ttcctaacaa
    11581 tgtaaaaaga gatttagcag taaataaagc gagattattt attataaatg ctactgctct
    11641 tgcacaagaa attggattag gacaaagaac aaatacaata atgcaagcag ctttcttcaa
    11701 attggcagaa attattccat ttgaagaagc tcaacaatat atgaaagatt atgctaaaaa
    11761 gtcttatgct aaaaaaggtg atgaaatagt tcaacttaac tataatgcaa tagatagagg
    11821 agcaaatgat atagttgaaa tagaagttga tccagcttgg gcaaatcttg aagtaactcc
    11881 attaaatgaa ccaaaagaaa cagctggttg tggtggatgt tgtcctactc caagtgactt
    11941 tgttaaaaat atagtaaaac ctataaatgc aataaaagga aatgatttac ctgtatcagc
    12001 attcttagga tatgaagatg gtacttttga aaatggtact tctgcttttg aaaagagagg
    12061 agttgcagtt gatgtaccta tatgggatgt agataaatgt atacaatgta accaatgttc
    12121 ttatgtttgt ccacatgctg caattagacc attcttgata aatgaagatg aattaaaagc
    12181 ttcaccagaa cctttggcta ctaaaaaacc agtaggaaaa ggattagatg gattagcata
    12241 tagaatacaa gtttctgctc ttgactgtgt tggttgtgga tcttgtgccc atgtttgtcc
    12301 agctcctgga aaagcattag taatgagacc aatagctgaa tcattagaag cacatgaaga
    12361 tgttaaaaca gattatctat ataataatgt agattataga agtgatttaa tgccagttga
    12421 tactgtaaaa ggttcacaat tttctaaacc attatttgaa ttccacggag catgccctgg
    12481 ttgtggagaa acaccttata ttaaattaat aactcaatta tatggagata gaatgatggt
    12541 tgccaatgct actggatgtt catcaattta ttcaggttct gcaccttcaa ctccatatac
    12601 aactaataaa aatggggaag gaccttcttg gggatcatct ctatttgaag ataatgctga
    12661 atatggattt ggtatgcatg taggagttga agctttaaga tctagaattc aacatgctat
    12721 ggaagaaaat atggataaag tagatgaaga tatagctact ctatttaaag attggatagc
    12781 aaatagacaa ttctctgtaa gaacaagaga aattagagat attcttgttc caaaactaga
    12841 agcattaaat acagattttg caaaagaaat attagattta aaacaatatc taattaagaa
    12901 atctcaatgg ataattggtg gagatggatg ggcttatgat attggttatg gtggacttga
    12961 ccatgttctt gcatctaatg aagatataaa tatattagta gtggatacag aagtttactc
    13021 taatacagga ggacaagcat caaaatctac acctactgga gcagttgcaa aatttgctgc
    13081 agcaggaaaa ccagttaaga aaaaagactt agcagcaata gcaatgtctt atggacatat
    13141 ttatgttgca caagtttcaa tgggggctaa ccaacaacaa gctttaaaag ctattaaaga
    13201 agctgaagct caccaaggac cttcaataat tattgcatac tcaccttgta tcaatcatgg
    13261 tatcaagaaa ggtatgtcac aagctcaaac tgaaatgaag cttgcaactg aatgtggata
    13321 ctggccaata ttcagatata atccatcagt tgaaaaatta ggtaaaaacc cattacaaat
    13381 agattgtaaa gaacctaaat gggaaaaata tgaagaatat ctaactggtg aagtaagata
    13441 ccaaactcta acaaaatcta atccagaaga agcaaaaatt ttatttgaaa taaataaaag
    13501 agatgctcaa aagagatgga gacaatataa gagaatggca gcactagatt atagtgaaga
    13561 aaaagaaact gaatagaatt aaataactat taaaaatgag agttgttatg aaattatttc
    13621 ataataactc ttttttctat aactgatctt agcttattta ggaatttata aaaataaata
    13681 atataaaata tatttaaaaa agaactatta tttataagta tttattgctt tataataatt
    13741 ctttttgtta taatataaat aataaaatac tttaaataga aaggagatta taatatgtta
    13801 caaacaagaa aagttggaat agttggagtt gggcatgttg gaagtcattg tgccttatct
    13861 atgttattac aaggtgtatc tgatgaaatg gttttaatgg atattattcc agaaaaagca
    13921 aaagctcatg caatagattg tatggatact ataagttttc ttcctcatag agctattatt
    13981 agtgatggag gaatacaaga gctttctaaa atggatgtca ttgtaatcag tgttggaagt
    14041 ttaacaaaaa atgaacaaag attggaagaa ttaaaaggct cattagaagc tataaaaagt
    14101 tttgtccctg atgttgtaaa agcaggattt aatggaattt ttgttacaat aactaatcca
    14161 gttgatatag taacttattt tgtaagagag ctttcaggtt tccctaaaaa taaagttatt
    14221 ggaacaggaa caggcttaga tagtgcaaga cttaaaagaa ttttaagtga agttacaaat
    14281 attgatagcc aagttattca agcatatatg ttaggagaac atggagacac tcaagttgct
    14341 aacttttcaa gtgctacaat acaaggagtt ccatttttag gttatatgaa aagtcatcca
    14401 gaacaattta aaggaataga actttctgtt ttagaaaaac aagtagttag aacagcttgg
    14461 gatattattt ctggaaaaaa ttgtacagag tttggaatag gttgtacttg ctctaattta
    14521 gtgaaagcaa tattccataa tgaaagaaga gtcctacctt gtagtgccta tttagatggt
    14581 gaatatggat attcaggttt ctatacagga gttccagcta ttattggaag taatggaata
    14641 gaagaaattt tagaacttcc tctagatgaa agagaaagaa aaggctttga agctgcttgt
    14701 gctgtaatga aaaaatatat tgaaattgga aaatcttata aaatagtata aaatatgtat
    14761 ggagggttaa agtgcagagt aaagaaagta atatcaaact gttgttatta ggtagagcag
    14821 tatccttatt tggaagtaca atatatttaa tagttttacc attatacata ttaaatacta
    14881 ctaaaaattt aaaaacgaca ggtattttct ttgcagcagt taattttcca acaattattg
    14941 tttccatttt tattggaaca ataattgaaa aatttaataa aaaaaatatt attttgatat
    15001 gtgatttttt aacttcaatg ttatattttg ttctattttt atatttaaaa aattttaatt
    15061 ctttaagttt tttattttta atttcattgc tcattaatat tgtttcaaaa ttttttgaga
    15121 tagcttctaa ggtattattt tcagaaatta atagccctga aacacttgaa aaatataatg
    15181 gtttacaaag ttttatggaa aatactatta taattgttgg accagttata ggtacttatt
    15241 tatttgttac atttgatttc aatttaattc tgataatagt ttctttggga tattttttat
    15301 cttttttaca agaactattt ataaaatatg aaaaaaatct taatttatca atagaaaaaa
    15361 ctaatttttt agaagatttt aaagaaggaa taagttatat aggaagtaat aaaattattt
    15421 taaatttctt tatattagta atgtttttaa atttttttat agcaaataat gatgagataa
    15481 ttaatcctgg aatattaatt agaaaatatg aaatatctga aaaattattt ggtttttcag
    15541 ctacttctta tggagcagga agtgtatttg caggaatttt tatttattat aataataaat
    15601 ttaaatttct aaaaaaacta aagctattat ttattttaaa tagttctcta atgtgtttat
    15661 taggtttact gtctataata ttatttaaat ataatcatta tatatatttt ataattttta
    15721 tattttttca atttctaatt ggaatgataa ctacctttgt aaatgttcca ttgatatctt
    15781 catttcaaaa aaatgttgag ataaaatatc aaagtcgttt tttctcaatt ttatcatttt
    15841 tttcaggagg tttaatccct ttggggattt tatatgcagg ctatttatca tcatatattg
    15901 gtgctgatat aacatatata atcaataatt tagctattat aactatagtt tgtttagtat
    15961 ttaaaaatat agaaagggat tgctaacaac ttaacaatcc ctttaaattt atttatatat
    16021 tttatttttt cttagcatat ttaatagagt caaatgcaac agcagtaaca attattatac
    16081 cttttataat atattgccag tatgggctaa cacctgtata agtaagtcca tagtttataa
    16141 ttgttaagat tataactcct gtgataactc ctgaaattct accaacacca ccatagaatg
    16201 aaactccacc aattacacag gcagcaatag catccatttc atacataaat cctaggttat
    16261 tagttgcaga tccaatacgt ccagcttcta agaaaccacc aaaagcatag taagctccag
    16321 atagagcgta aattcctata agagttaaaa caacatttac tcctgatact tttgcagctt
    16381 ctgggtttcc accaacagca aatacatttt taccaaattt tgttttgttc cataaaaccc
    16441 acataattaa agttgcaata gcagcatata taattaagta tggtattgta tatgaaccta
    16501 tttgtatata gccttgtgcg aatttactat atttttctac aaatccagaa attggagcag
    16561 cccctgcttt atcatagtaa agagaattta tcccatacac aatagtcatt gttcccatag
    16621 tagctatgaa tgggtgaaca tttagagttg ctacaactat accatttata cttgctataa
    16681 ctataccaac aactacaaca atcaatatag ttgtaaatat tgaaaattct cctaatgttg
    16741 ggaatgcttt atttacattt gtcattgatt gtaaaagtgt tccagatata acagcggaaa
    16801 gtccaacttg tctacctgct gataagtcag taccttgtgt tactataagt ccagcaacac
    16861 caagtgcaat aattgttctt acagatgatt gtgtaagaat atttttaaag tttcttatac
    16921 ttaaaaaagt aggttctttt attattattg caataagcat acaaaataat acaagataca
    16981 atccactttc tataataatt tttttataat ctatttttcc ttcatttgtt cttgcaatca
    17041 tttttattct ccttcttaat tttatagata tttagctgat agctccatta tttcttcttg
    17101 atttgtttca gatgttttaa caattcctgc aaccctacca ttactcataa caagtattct
    17161 atctgttact cctaaaagtt caggcatttc agaagaaatc attataattc ctttatcctt
    17221 tttagcaagg tctatcatta attgataaat ttcatatttt gctaaaacat caatacctct
    17281 agtaggttca tcaagcataa gaacttctgg ttcagttagt agccatcttc caataattac
    17341 tttttgttga tttccaccag aaagacttcc aattttggta gagtatgaag gagtttttac
    17401 tctcatacta tctactatcc atttagtatc tttctctata tctttatttt taagaagttt
    17461 aaatttattt ttatatctat ctaagttaga gataacagag ttaaatgcta tatccaacat
    17521 tgaaaatatt cctgtacttc tacgttcttc tgttactaag gcaaaaccat tttttatggc
    17581 ttcttctgga tttctatttt ttacagtttt accatttaaa ataatttcac catgttcttt
    17641 tggtctcatt ccaaaaatag tttcaactat ttctgttctt ttagaaccaa caagtccagc
    17701 tattcctaaa atttcacctt tataaagttc aaaacttaca tcttgtatag aaggttgatt
    17761 taaagctgtt agatttttaa cttctaacat catttcttta gctgtgttat cttttttagg
    17821 gaaacgttca gttaaatctc tacctaccat catacttata atttgttcag ttgaaatttt
    17881 tgaaacatcg ttagttgaga tccatttacc atctcttaaa atagtaattt catcagaaat
    17941 catttttatt tcttccattt tatgagaaat ataaataatt ccaactccac tttcttttaa
    18001 ttttttaatg attttaaata agtgatcaac ttctttttca gttagtgaag aagtaggctc
    18061 atccataact attacttttg acttatatga tactgcttta gctatttcta tcatttgtct
    18121 ttcagcaata ggtaattctg caactttttt tctaggatct accttaatat ctaaatcctt
    18181 aaagatatta atagtgtcat tatacatttt cttttcatct acaaaaaatc ccttcattgg
    18241 atatctacca agccaaatat tatcaagtac atttctttgt aaaacttgat ttaactcttg
    18301 gtgaaccata gaaactccat tttctaaggc ttcttttgta gatttaaaat taacttctac
    18361 tccatctaat aaaatctttc cactattctt ttcataaatt ccaaacaaac atttcattaa
    18421 tgtagatttt ccagctccat tttctcccat tagagcatgg acagttccag gttttagttt
    18481 taattgaaca ttatctagtg cttttactcc aggaaactct ttggaaatat tttccatttc
    18541 taatacatat tttagatttt ccataaatac cctattcctt ttcctttatt ttccattttt
    18601 taaaaaaagg agattgatgt acaatctcct ttaagattac tatacaatta attcttattt
    18661 gaagtctgca acattagatt tatctattcc aatgctagga attaatatta ttttattatc
    18721 taattttaaa tcagttcctt cagtaggttc ttttccttgt gctaaattaa ctaccatatt
    18781 gaatgttgca cttgcttgtc cttttgcatc gttaagaaca gttcctgcca tttcaccagc
    18841 ttctattttg actaatgctt ctggtaatgc gtcaacacca aatgtaggta aaacttttcc
    18901 agcagctttc attgattcaa tagctcctaa tgccattcca tcgttattac agataactac
    18961 ttctattttt gaaccattag gtcctgataa ccaagcatcc attttatctt ttgcagtagc
    19021 agtatcccac atagcagtat cttggtgtaa ttcttcagtt ttaattccat gatcatttaa
    19081 agtagagata gaatatttag ttcttgcaac tgcatctggg tgtccaggtt ctccagttaa
    19141 cattacatat tggataactc catctttatt taagtcaaga tcaggatttt ctttccataa
    19201 tttttcaatt aattcacctt gtgcaattcc ttgtgcatta gggtcaattc caacataata
    19261 taatttgtca taagaagcta ttgcttcatc agaaggtttt ctgttataaa atacaactgg
    19321 aacatttttt tcttttaata aattaataat tccatccgct gcagatgcat caactaagtt
    19381 tatagcaaaa gctttaactc ccttttcaag aactgcttct atttgttctt tttcagtagc
    19441 aacactgttt tgagagtcaa tagcagttac ttcaactgta tcagctttag ctgctgcttc
    19501 agcttcaaat gcttttctga ataaagctat aaagttatca tcaaatttat aagcagttaa
    19561 ccctattgat aatttttctg ctgcaggagc atcagtttta gcttcttcct ttttttctcc
    19621 gcaagcaact agtgcagatg ctagaataat tgaacccaat aacataccaa attttttcat
    19681 ataaataccc tcctaaataa tttaataaaa taatgatttt ttattgttgt tatatatttt
    19741 catatataac acaatatata atttttttta gtgttttgtc aatagatttt tattaaaaat
    19801 aaataaattt tccacaattt agaaaaaatg tatttttaca agacaaaaaa ttttagctat
    19861 ctaacttagt taatatctaa ataaaaagtg ccacagctcc ttttatacct gcttcattac
    19921 ctaaaacacc cacttttatt tctaaatttt caagtgcagg aggcatagta tattttttta
    19981 atttctcttt tactggaagt aaaatttcat ctcctgcaag agagatacct ccacttataa
    20041 ctatacattc aggattaatt atatttaaaa gatttcctat acccaaagct aagtaatcac
    20101 tttcatattc tattaaatct tttgaaaatt catcaccttt tctagcagta tcaaaaatat
    20161 tttttgcttc aagttcatct aaattcccat taatctcctt aaaaagtaaa ttattttcat
    20221 ttagttttaa tctttctttg gcttctttta caagagaatt agctgaggca taagcttcaa
    20281 aacatccatt ttgtccacaa ccacaggtct taccatcttt aacaactttc atatgcccaa
    20341 tttctccacc aactcctgac ataccagaaa taagatttcc attataaaaa ataccaccac
    20401 ctattcctgt tcctattgca atagttattg aagatttttt tccttttgca gctccaaaaa
    20461 tggcttcacc ttgtgcaatg atattagcat cattttctat tcttgtttct attccactta
    20521 atctttccat tttttctttt aaatttagat ttctttccca atcaaaattt gcaaagaacc
    20581 ctactatact ttgatttttt acaggtccag gaatgccgat acctattcct acaacagaaa
    20641 aaagtggaat ttctttttcc aatatcaatt tttttgcagt ttcccatatc ctttccaatg
    20701 tcttatcaac attttgatga gagtgagttt taataatttt gctatttatt aaatttccct
    20761 ctgaatcaac tattcctatt tttgtgttag ttccacctaa atcaatacca atataatgtt
    20821 tcatagcctc tcctcatata atgatttatt tattttctat gttttcccac catttagaga
    20881 aagaattttc cttatgtaag taaatttttt ctcctattat aggtgtaagt aattttatat
    20941 ttgtattttt tgttaattca tctaatctct ttaaaggatc atcccaagta tgattagata
    21001 atttaaattt actattatgt attggaagta agttttccac ttccatatct tgtgatgcca
    21061 ttagcacatc ttctggttta gaatgaatta aagaccattc tttattatat tgaccacttt
    21121 ccattgcagc aaggtcaatc tttccaaatc tttctttaaa ttctttaaat cttccactat
    21181 atccaccatc tccacttagg aataatttat agtttttatt attaattttt tcttctatta
    21241 aatatgaaac ccatagactt tgatttctat taaagaaact tcttcctgaa aaatgtcttg
    21301 cttctaaagc ataaattttt aaattatcat ctataacaac ttcatcatcc caatcaacag
    21361 ttgtaatttt atcttcatca tagccccatc tcaaaagatg tgcatctact cctaatggaa
    21421 ctattatttt agccacttta ttctttaatt ttttgatagt aggataatct aaatgatcat
    21481 aatgatcgtg agtaataagt aaaatatcta tttcaggtaa atcatctaca tcataaacat
    21541 ttgttccttt aaaagcctta ttagtaaatg gaacaggtga agcatattta gaaaaaacag
    21601 ggtcaaccaa gactttcttt ccagatattt gtataaaaag agaagaatgt ccaaaccata
    21661 ccattacatc ttcactaggg tctaagtttt ttaaatcagt tttaatactt ggtaggtcaa
    21721 aatctggaac tgttccttct ggatcttttt caaatgcaaa ttctaaaagt ctttttattg
    21781 gagttttttt agtatctgtt aataattctg tactttcttt atttttaaat tctccatcta
    21841 catagttttt agaggctttt actttctcta aactttttcc acttggtaag gcaccaaaag
    21901 cgggagtttt cataaataaa tatgtagcaa tcattaatat aataaatatt attattaggt
    21961 aaaataatat cttaaataac tttttcaaaa tttactcctt atttcttttt actttttaaa
    22021 atttctttta aaatgaatgt tgttgctata acgccatcat tagtagcagt agcaatttgt
    22081 cttacatctt tttctcttat atctccaata gcatacattt tgtcagttct tgttttcata
    22141 gtttcatcag ttattatgta acctgtttca cttaaactaa caaattctcc atataattca
    22201 agattatttt ttgtacctaa atataggaaa acaaaatctg ttgctactgt ttctttattt
    22261 ccatctactt ctaaatctaa tcctgttaca aattcttcac cttttatttc taaaagttta
    22321 actttctttg taattttaac attttctttt gataaaatag cttcttttaa ttcttcattg
    22381 caatctaagt catcagaagt taaaaaaaca ttaacttcct ttgcatatct agttaaaaat
    22441 agagattctt caataagttc atcccctttt ccaactaatg aaacgactct accttttgta
    22501 aaagctccat cacaagttgc acaatatgaa acacctgcac ccaagaactt gttttctcct
    22561 ttaatttttt tagcaccaat ttttcctaat ccagttgcta ttataatata ttttgttttg
    22621 aaatttcctg catctgtttt tacaactttt atttcttcat aaggatcaaa ccccaaaact
    22681 gttgcaggtt ttatttcaca accaaagtct aaggcttgct ttttcattgt gtcataaatt
    22741 tccttaccag aagctcctat atgagaacca ggatagttat ctatttgatg agtcattacc
    22801 atacttccta ttccttcttt ttctaagata agagttgaca aatttcctct ccctgcatat
    22861 attcccgctg ttagtccagc aggacctgca ccaactatta caacatcata tattttttcc
    22921 attgttacca tctccttaac tttttaaagt attccaactc ttgctaaaaa taatttttct
    22981 tctccaatag ttgtattatc tgtatgtcca ttatagacaa cagtgtcact tggtaatttt
    23041 gataattttt ctaaactatg acataacatt tctaaatcac cagtaggtaa gtcatatcta
    23101 ccataacttc ttctaaataa tgtatctcct gatattaaaa ttttatcttt ttcataataa
    23161 aaacttttag aaccgatagt atgtccagga gtatctataa ctttaaaatc tcctaccata
    23221 tcgccttctt ttactgtatg aatttctcct ttaaatttaa aaaattctcc aaaaattcta
    23281 tctgataagc taagttctga attatataaa aaatcttttt cctcttcacc aatatagact
    23341 tttgcttctg gatagtgaga agataaatca tttaaacctt caatgtgatc tccatgtcca
    23401 tgtgtcaata ctatatattt taaatttaaa ttatgctcac ttataaaatc ataaacttta
    23461 tctaaattac gtcctccaca atcaaaaaaa taagctatat tattttcatt ataagctaag
    23521 aaacaatttg ttccataagc tcccaaatga aagcatttta ccctcaatgt tcttctcctt
    23581 tcacgtattt atattaaacc taatacatta taacaaattg aactaaaata gtctacctta
    23641 gagatttata tttttaataa gaaattttaa atcatataaa aagagaattt ttttagaaat
    23701 ttctattcta aaaaaattct ccaaattatt ttattttggt attctataaa tttctatttc
    23761 tttccctaaa aatttttcag cagttggctt aaaatgatat gtttccccag taacaaaaaa
    23821 tatcactttt cctttttctt ttttatcatt taaaagatta agagtagtca aagtttgagt
    23881 agccctttca actatttcta ctgctggatc aactacttta atttttatat ttttttcaat
    23941 atcttttctt ataagtggat aatgagtaca acctaagact aaagtatcag tatttttagg
    24001 aatttctgat aaatatttat ttagaagttc ctttctattg tcaaaggtat cccaaccact
    24061 ttctatcatt tgtgcaaact caatacaagc aatttcttta acattcaact cactatcaag
    24121 cattttagct ttatttttat agccatgaga ttctgctgta aatttagttg agattacagc
    24181 aatattctta tttttagtag ttttacttgc tatcttcact cccgcttcta caattccaat
    24241 tataggtaat gaaaactttt ctcttaaata atcaatagca gcggttgaag cagtattaca
    24301 agctactatt actaatttac aattattttt cacaaaaaaa tctaaaattc tttcagttaa
    24361 tttttggagt tcatttttag tttttccaga accataagga aaatttccat tatctccata
    24421 atatatatag tcctcattag gaagagattt tatcatttct tttagtacag ttgttcctcc
    24481 taaaccagaa tcaaatatac ctattttttg agttttttct gccatttctt ttccttcttt
    24541 ttatagatta taataaatac tttttaataa tatcatattt tttttataat atcaattatt
    24601 ccagcttgaa taaatcaaat aactcttctt ttgtcaaact agaaaaactt cccttagaat
    24661 tttctacaaa aatatcactt aattctttct ttttattttg tagatttaaa attttttctt
    24721 ctattgtatt ttttataata aggctaaata c
//
