LOCUS       c00062_NZ_LUHG..       15262 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_LUHG01000046.1 Hydrotalea flava strain CCUG 51397
            60_A2_NODE_42_length_20157_cov_273.135_ID_83, whole genome shotgun
            sequence.
ACCESSION   NZ_LUHG01000046
VERSION     NZ_LUHG01000046
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:00:24
            Original ID  :: NZ_LUHG01000046.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 4895
            Orig. end    :: 20157
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15262
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[14895:18157]"
                     /cutoff="10000"
                     /detection_rule="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /neighbourhood="10000"
                     /product="fatty_acids-unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13262
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /neighbourhood="10000"
                     /product="fatty_acids-unassigned"
                     /protocluster_number="1"
     cand_cluster    1..15262
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /kind="single"
                     /product="fatty_acids-unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15262
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="fatty_acids-unassigned"
                     /region_number="1"
                     /rules="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /tool="gutsmash"
     CDS             complement(123..1202)
                     /locus_tag="ctg62_6"
                     /transl_table=11
                     /translation="LSGKRDSNPPPSVWETDALPDELFPLMLCNVQKKFIPYICSMQVS
                     DISIIFMGTPDFAVASLDALLQAGCNIVAVVTAPDKPAGRGMQLQQSAVKQYAVTHGLS
                     VLQPEKLKHPDFIATLQSLQPQLQVVVAFRMLPKVVWSLPAMGTINLHGSLLPQYRGAA
                     PINWAIINGEKETGVTTFKLQHAIDTGNILLQQSMPIFPEETAGELHDRMKIIGAQLLV
                     KTIQQLAEGTLKEQPQALLSNNETHTIKHAPKIFTETCQINWNHSAAAIQHLIHGLSPY
                     PGAFTFLKEKKLKIYRCKVEPNASNTIPGSIDTDGKTCLKIAAQDGWVVLTDLQLEGKK
                     RMDAATFLRGYHHLLQTNE"
     CDS             complement(1199..2485)
                     /locus_tag="ctg62_7"
                     /transl_table=11
                     /translation="MNRAAVQKIISIQSYLLLALCLLIFNSNFAQATVPILPGAYQTQT
                     YFKWLQHKNVALFANHTATIGDTHLADTLLKAGIHIVKAFGPEHGFRGKADDGKLIQDN
                     IDPITGIPIISLYGKKRKPTPDDLKNVDVIIIDIQDVGTRFYTFISSVQEMLEAAFENN
                     KSVILLDRPNPNGFYVDGPVLDTAYKSFVGMQPIPTVYGMTIGEYANMLIGEHWLSKEA
                     DSHFYQYYAQHGFSRYLPSFLIVRCKNYDHNSKYRLPIPPSPNLPDMASVYWYAGNCLF
                     EGTVLSEGRGTPHPFCYIGHPDLPKNLFAFTPTPGPGATNPKLNGKTCYGWNLYASEKE
                     VLATIHNQLPIQYILKAYALFPDKTHFFILPKQGNEKMNAFNRLAGSDQLMQQIQAGLT
                     EEEIRASWQPQLAAFKKIRKKYLLYKDFN"
     CDS             2728..3183
                     /locus_tag="ctg62_8"
                     /transl_table=11
                     /translation="MQQVKKGDTVKVHYHGKLEDGTTFDSSEGREPLEFEVGSGMVIAG
                     FDDGVTGMQIGEKKTIHIPADEAYGPVQEEMIMEFPRDRFPDDMTPEVGMQLNMSNGQG
                     QNFPVVIVDVKDTVVILDANHPLAGKDLVFDLELVAIAGGSPLIIMP"
     CDS             3326..4582
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M20"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg62_9"
                     /sec_met_domain="Peptidase_M20 (E-value: 1.4e-18, bitscore:
                     57.7, seeds: 360, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKDYSYSVVERFMRYVQIDTQSDPASTNFPSTEKQKQLAQLLAA
                     ELKQMGIDDAKMDEYGYVYGTILSNSPQKNIPVICFCAHMDTSSDCSGTNVKPILHQQY
                     KGTTIVLPDDDTQVLTVDNYPYLKEHIGKDIITASGNTLLGADDKAGVAIIMDAAQYLM
                     QHPEIKHGTIKILFTPDEEVGRGTEYVNLQYLGADYGYTLDGGEAGHLEVETFSADAVT
                     ITIYGVSAHPGYAKNKLVNALKLAGELLTVLPKGEWSPETTEKKQGFVHPVRMEGIAEK
                     ATIEFIIRDFETANLIKYEERLKHFVETVVGCHPGSSFEMVVKEQYRNMYEVLQHHLQV
                     IAYAEEAYQRTGLVVKKEPIRGGTDGSRLSFMGLPCPNLFTGMQGIHSKKEWVGVKDMK
                     LAVETLVHLSQIWEEKTLK"
     CDS             4591..5301
                     /locus_tag="ctg62_10"
                     /transl_table=11
                     /translation="MKLKTWIAVALTGILMSCQAQKNSNEALSPDTFQQQIQQPNVQIL
                     DVRTAEEFAGGHIEHALQADWLLPDQFQERVKSIDKDKPVYVYCLSGVRSAAAADWLRA
                     HQYKTVYHLAGGIQAWKQANKPLVGESNEPQITMEQYQQMIQQAGPVTLVDFGADWCPP
                     CRKMQPVLDALKTTYGPKLNIVKIDAGKQTDIMKQMNLPAIPVFIIYKNGQEVFRKNGI
                     VAQSDFDAAIKPLL"
     CDS             complement(5380..5664)
                     /locus_tag="ctg62_11"
                     /transl_table=11
                     /translation="MKRYQPLHTITLALVLIFAITGILSINGCAPTKAVAAKSGAQLWA
                     ENCQRCHNTPSPASFSAEQWETIGMHMQTRALITQAEREKIVEFLKSSR"
     CDS             complement(5676..6896)
                     /locus_tag="ctg62_12"
                     /transl_table=11
                     /translation="MKHKIYKLMGLIALAMGGTFPHLIAQTSGGLDSTVLDRLNALEQQ
                     ANYQKPGNDHFMVAGLTTFGFAASKSTNTLGGVSAISKTNSLADADHYEFSPMFLWRHG
                     KKFLLEFEPSFSNNGLGVNWADVSYFAAPNIIIRAGYLVLPFGTYAKREAAGWIDKLAT
                     DPMGIADMTPTDYGVEVEGGLPLGSMKLNYDVALSNGSQLLGNGTLTSGNIVDNNNNKT
                     ITARIGWLPFSNSSLEIGVSGMFGKVGDLGSPYQNATGNMYAFDLNYVKTFNPVLVNVK
                     AQYNIQNISNENYVNPNDSTQSYSFNNHTTAGFVQCSIRPTEANNFLKNFEIAGRYTSY
                     NLPGNSTFGANQHSIAVGLDYWLTWRTVVKATYETYTGNSTASKLLGAYNGTTNTNTFY
                     LQFSIQL"
     CDS             7670..8599
                     /locus_tag="ctg62_13"
                     /transl_table=11
                     /translation="METFISFWWLIVLLIILFTGMVSVTQGNITVLTMFGKYRRILRPG
                     LNFKIPVFEQIYKVISIQNRSVELEFQAVTVDQANVYFKSMLLYSVINAEEETIKKVAF
                     KFISDKDLMQALIRTVEGSIRAYVATKKQAEILLLRREIVEYVKAQIDHSLEEWGYHLQ
                     DLQINDITFDKAVMESMSKVVASNNLKAAAENEGQALLITKTKAAEAEGNAIKISAEAE
                     KEAARLRGQGVALFREEVAKGMSQAAEQMKQANLDTNVILFSMWTEAIKNFAEVSNGNV
                     IFLDGSPEGMDKNMQQIKAMLQMKTNKS"
     CDS             8760..9461
                     /locus_tag="ctg62_14"
                     /transl_table=11
                     /translation="MFHLLQVAATPIADTLHKAATAIPPVEEKISMWDMLQKGGFIMYP
                     LYFLLVLALFFFFERLIAIRKASKIEPNFMSIIRDNILTGNISAARSLAKNTPNPVAKM
                     IDKGLQRIGKPIDAIEKSMENVGKLEMYNMERNLSVLSLIAGIAPMFGFLGTIVGMVQL
                     FYGIASTGEYTLNTIAGGIYTKMVTSATGLIIGLMAYVAYNYLSTQIDKTANKMEVASA
                     EFIDILQEPTK"
     CDS             9579..9986
                     /locus_tag="ctg62_15"
                     /transl_table=11
                     /translation="MNIRQGIRKRHAEVHTGALNDILFILLLFFLIVSTLANPNVIKVA
                     NPKAKSDTKAKQTVVITVDKDQNIYIGQKLVPFDQLESQLQAFLAKETDKPSVVINGDS
                     TSHLGTAIKVMQVIKKLGATPVVAVDNNGVQ"
     CDS             complement(10001..10411)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg62_16"
                     /sec_met_domain="HBT (E-value: 1.1e-13, bitscore: 41.9,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATDEMNFHTRKWVKPEDLNPNHTLFGGRLLQWIDEEAVIYAIIQ
                     LENAKVVTKYISEINFVNAPKQGDIIEIGIIATEFGKTSITMRCEVRNKLTREQILTID
                     KLVFVNLGEDGKPKAHGKTQITYVKDRVVPKS"
     CDS             complement(10425..10820)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyoxalase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg62_17"
                     /sec_met_domain="Glyoxalase (E-value: 4e-16, bitscore:
                     49.8, seeds: 82, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQEIVQMALLVRDYDEAIAFYTQKLQFTLIEDTVLTEPKRWVVI
                     APPGSKGCRLLLAKAASEEQEKCIGKQSGGRVFLFLHTDNIQRDYTNLQQQNVNIIHAP
                     EVQPYGTILVFEDLYGNKWDLIQPITT"
     CDS             complement(10887..13262)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: HCDH_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: HCDH"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg62_18"
                     /sec_met_domain="ECH_1 (E-value: 9.4e-19, bitscore: 58.0,
                     seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH (E-value: 1.1e-16, bitscore: 51.7,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH_N (E-value: 3.6e-46, bitscore: 147.7,
                     seeds: 60, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRIIKKVVVLGSGIMGSRIACHFAGTGVEVLLLDMLSKDTGESN
                     NPTVRNKLVNDALQTALKSNPSPVFTPDVAKKITTGNFTDNMKDIATADWIIEVVVERL
                     DIKQQIFAEVEKFRRPGTLITSNTSGIPIHLMAAGRSDDFQQHFCGTHFFNPPRYLKLL
                     EIIPTAHTKQEVIDFLLQYGDLYLGKTTVLCKDTPAFIANRIGVFSIMSIFHIMEQQGL
                     SIDAIDALTGPVIGRPKSATFRTADVVGIDTLVKVAKGVAENCKEDEAKNIFQIPAWLE
                     KMVQDNRLGDKTGQGFFKKTKGAGGKEIQVINLQTFEYEARQKPKFAALEAAKPIEDLK
                     ERIKLLQQSPDTAGNFYRSFHYALFSYISYRVPEISDELYRIDDAMKAGFGWEIGAFET
                     WDLLGVAKTVHEMKLAGYQVAHWVEEMLAAGKTSFYALEKGKKKFYDVPIKAYRFMPGE
                     DSFIVLSNFTDGLIWKNSGCKLYDIGNDVAALEWSTKMNSIGSEVLEGIQQSITVAEDK
                     FKGLVIANPDPNFSAGANVGMIFMLAIEQEYEELDMAIRMFQNTMMRVRYSAVPVVAAP
                     HGLALGGGCELNLHADKVCAAAETYIGLVELGVGLIPGGGGTKEFVLRASDELHKDEPE
                     LNTLKERFLTIATAKVATSAFEAYKMGILRKDRDAILLNPDRRIAAAKKAVIDLYDAGY
                     TMPTQRKDITVLGRSALGALLVGINAMKRGGYVTDHDALVATKLAHVMCGGDLSAPTQV
                     SEQYLLDLEREAFLSLCGEKKTLERIQSVLKTGKPVRN"
     CDS             complement(13612..14646)
                     /locus_tag="ctg62_19"
                     /transl_table=11
                     /translation="MQAILFTHVYKHTRKKMLLLAVCIGLIVTAKATDSTYAEKLGFPK
                     GAKVVILHVDDAGMSYESNEGAILALTKGVATSTSVMMPCSWVPGFVQFLKEHPQIDAG
                     LHLTLTAEWKNYRWGPLSGKPATPGLVDQQGCLWPNVTDVVQHASAAEVATEINAQLQR
                     ALTMGFTPTHVDTHMGTLLATPAFAEQYIQLGIKNHIAVMLPGGHATLIALQMHASQQL
                     MAQMHFMGNLLWKAGLPVLDDLYNESYDWVNPTNTLQNDSLLQAYRTNRYIAAFDSLQP
                     GITMVIMHCTTTTPQFKYISDSGPTRRGDLLAMLDPRLRQYIQQKGIILTTWRELMERR
                     SRLP"
     CDS             14924..15262
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FAD_binding_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg62_20"
                     /sec_met_domain="FAD_binding_2 (E-value: 1.8e-09, bitscore:
                     27.5, seeds: 62, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGELQIKKEAKKYDAIIIGSGAGGGMAAYVLANAGLKVCLLEAGP
                     NYDPAINSDQLKNPWESPRRGASTKFRPFGDFDGCYWGWEIDGEPYTHANGTKWEWWRA
                     RMVGGRTNH"
ORIGIN
        1 aagtattggg ggcattaccc aatattaagg aagatgatgg tttattgttg cgtattagca
       61 atgcagctgc tgcagtattg ggtatggcag ataaacgatt tccggttacg gtgcaatatt
      121 agctactcat ttgtttgcaa caaatgatgg tatcctctta aaaaagtggc tgcatccatt
      181 ctttttttgc cttctaattg caaatcggtt aacactaccc atccatcttg tgctgctatc
      241 tttaagcatg ttttaccatc ggtatcaata ctaccgggaa ttgtatttga ggcgttgggc
      301 tctaccttgc atcggtatat ttttagtttc ttctctttta aaaaggtaaa tgcaccggga
      361 tagggtgaga ggccatgaat taaatgttgg atggctgctg cagaatgatt ccaattgatt
      421 tgacaagttt ccgtaaaaat tttaggtgca tgttttatgg tgtgtgtttc attattgcta
      481 agtaatgcct ggggctgttc tttcaacgtt ccttctgcta gttgttgtat ggtttttact
      541 aataattgag caccaataat tttcatacgg tcgtgtaact cgcctgctgt ttcttccggg
      601 aaaatgggca tggattgttg caataatata ttgccagtat caatagcatg ttgcaattta
      661 aaagtggtaa cacctgtttc tttttcccca tttataatag cccagttaat gggagctgct
      721 cctctgtatt gtggtaacaa tgatccgtgt aaattaatgg tacccattgc tggtaggctc
      781 caaaccactt tgggcaacat tctaaaagct accaccacct gcaactgtgg ttgaagcgat
      841 tgcaatgttg caataaaatc gggatgtttc aatttttctg gttgaagtac agataaacca
      901 tgcgtcaccg catattgttt tacggcactt tgttgtagct gcatccccct gccagcgggt
      961 ttatcgggtg cggtaactac tgctactata ttacaaccgg cctgtaataa tgcatcgagg
     1021 gaagcaactg caaaatcggg tgttcccata aatattatgc tgatatcaga aacttgcatg
     1081 ctgcaaatgt atgggatgaa tttcttttgt acattgcaaa gcattagcgg aaatagctca
     1141 tccggtagag catcagtttc ccaaactgaa ggtggcgggt tcgagtcccg ttttccgctc
     1201 aattaaaatc tttatacaaa aggtattttt ttctgatttt tttgaatgcg gctaactgtg
     1261 gctgccagct tgctcttatt tcctcttctg ttaatccggc ttgtatttgt tgcatcagtt
     1321 ggtctgaacc ggccaatcgg ttaaatgcat tcattttttc attaccctgt ttgggtaaaa
     1381 taaaaaaatg cgttttatca ggaaacaatg cataggcttt taaaatatac tggatgggta
     1441 attggttgtg tatggttgct aatacttcct tttccgatgc atacaaattc caaccataac
     1501 aggttttccc gtttagtttt gggttggtgg caccaggccc gggtgttggt gtaaatgcaa
     1561 acaggttttt aggtaaatcc gggtgcccga tataacaaaa tgggtgtggt gttcctctgc
     1621 cttcactcag aacagtaccc tcaaacaaac aattgcctgc ataccagtaa acactggcca
     1681 tgtctggtaa attgggcgat gggggaatgg gcagcctgta tttgctgttg tgatcataat
     1741 ttttacaacg tacaattaaa aaggaaggca gatacctgga aaagccatgc tgtgcatagt
     1801 attgataaaa atggctgtct gcttctttcg aaagccagtg ttctccaatc agcatgttag
     1861 catattcccc tatcgtcatg ccatacaccg ttggtatagg ttgcatgcct acaaaacttt
     1921 tatatgcagt atctaaaaca ggcccatcaa cataaaagcc gtttggattg ggcctgtcta
     1981 aaagtataac cgatttattg ttttcaaatg cggcttccag catctcctgt accgaagaaa
     2041 tgaaggtata aaatcgtgtt ccaacatcct gaatatcaat gataatcaca tcaacatttt
     2101 ttaagtcatc cggtgttggt tttcttttct tgccatatag cgaaataatg ggtatgcctg
     2161 taatggggtc tatattatct tgaattaatt taccatcatc tgcttttcct ctgaaaccat
     2221 gttcggggcc gaaagctttt acaatgtgta tgcctgcttt taataatgta tctgccaaat
     2281 gcgtatcacc aatcgtagcg gtatgattgg caaatagtgc cacatttttg tgttgcagcc
     2341 atttgaaata ggtctgagtt tgataagcac ccggcaatat aggaaccgtt gcttgtgcaa
     2401 aatttgaatt gaaaataagc aggcaaagtg ccaataaaag gtaggattga attgaaatta
     2461 ttttttgaac tgctgcacga ttcattgtta gatttaaatt atttagaata tatttttgca
     2521 tatggtctat tctttctttt gaatatggga gttgaaagtt aacgaaaaat aattgtctgt
     2581 tttagcagtt cggcgtattt tgcaggcgaa gccggttttc aattctttct gatagttgat
     2641 gttgaatgct tccgtagaag tttgcgatgc aaccacagtg gagaggtgaa ataggagcta
     2701 acttcttaaa caacaaaaaa gcaaacaatg caacaagtta aaaagggtga tactgtaaaa
     2761 gtacattatc acggaaagtt agaagatggt actaccttcg attcatctga aggccgtgaa
     2821 ccacttgagt ttgaagtagg cagtggtatg gtaattgccg gttttgatga tggcgtaacc
     2881 ggaatgcaaa ttggcgaaaa gaaaaccatc catattcctg ccgatgaagc ttatggacct
     2941 gtacaggaag aaatgattat ggaatttccc cgtgatcgtt ttcctgatga tatgacaccg
     3001 gaagtgggaa tgcaattaaa catgagcaat ggccaaggcc agaattttcc agtggtgatt
     3061 gttgatgtaa aagatacagt agttattctt gacgccaacc atcctttggc tggaaaagat
     3121 ttggtttttg atttggaatt ggttgcaatt gctggcggaa gcccattaat tatcatgcca
     3181 taacctatta ttgaattagt tgataagccc ggatatattg ttccgggttt tttatgcatg
     3241 aatcgttaag attatcttgc taaactgcgt atttaggcat actgcacaag aattgtatta
     3301 aattgccttt aaaatttttc gggatatgtt aaaagattat tcctattcag tagtagaaag
     3361 attcatgcgg tatgtgcaaa ttgatacaca aagtgatccc gctagcacta atttcccttc
     3421 cacagaaaaa caaaaacagt tagcacagtt gttggcagct gaattgaagc agatgggtat
     3481 tgacgatgca aaaatggatg aatatggtta tgtttatggt acaattctct ctaacagccc
     3541 acaaaaaaat atacctgtta tttgtttttg tgctcatatg gataccagtt ccgattgtag
     3601 tggtacaaat gttaaaccaa ttttgcatca gcaatacaaa ggcaccacaa ttgtgttacc
     3661 ggatgatgat acacaggtac taacagtcga taattatcca tacttaaaag aacatatcgg
     3721 aaaagatatt attactgcat ccggaaacac attattaggg gcagatgata aagcgggggt
     3781 tgctattatt atggatgcgg cacaatattt aatgcaacat cctgaaatta agcatggcac
     3841 tattaaaatt ctatttacac ccgatgaaga agtaggccgc ggtacagaat atgtaaactt
     3901 acaatattta ggagccgatt acggatatac attagatggt ggtgaagccg gccatttgga
     3961 agtagaaact tttagcgccg atgctgtaac gattaccatt tatggcgtta gtgcacatcc
     4021 gggctatgca aaaaataaat tggtaaatgc tttaaaactg gcaggtgagt tgttaaccgt
     4081 gttgccaaaa ggagaatgga gtcctgaaac tactgaaaaa aagcagggct ttgtgcatcc
     4141 tgttcgtatg gaagggattg cagaaaaagc cactatcgaa tttattattc gcgattttga
     4201 aacagcgaat cttataaagt atgaagaacg gctgaaacat tttgtagaaa cagtggttgg
     4261 atgccatcct ggttctagtt tcgaaatggt agtgaaggaa cagtatagaa atatgtatga
     4321 ggtattgcaa catcatctgc aggtaattgc ctatgccgaa gaggcttacc aacgtactgg
     4381 ccttgttgta aagaaagaac ctattagggg tggtacagat gggagccgtt tgagttttat
     4441 gggattaccc tgccctaatt tatttacggg tatgcagggt atacatagca aaaaagaatg
     4501 ggtaggggta aaagatatga agttggcagt tgaaacttta gtgcacctta gccagatttg
     4561 ggaggaaaaa actttaaaat agataaatat atgaaattga aaacatggat agcagtggct
     4621 ttaacaggca ttttaatgtc atgccaggca caaaaaaata gtaatgaagc gttaagtccg
     4681 gatacttttc aacaacaaat acaacaaccc aatgtgcaaa ttttagatgt tagaacagca
     4741 gaagaatttg caggtgggca tattgaacat gcattgcagg ccgactggct tttgccggat
     4801 caattccaag aaagagtaaa gagtattgat aaagataaac cggtatatgt atattgttta
     4861 tccggtgtta gaagtgcggc tgctgccgat tggttacgtg cccatcaata taaaacagta
     4921 taccacttag ccgggggtat tcaggcatgg aaacaagcca ataaacccct agtaggtgaa
     4981 tcgaatgaac cgcaaattac catggagcaa tatcagcaaa tgatacagca ggccggcccc
     5041 gttactctgg ttgattttgg cgccgactgg tgcccgccat gcagaaaaat gcagcctgta
     5101 ttagatgctt taaaaaccac ttatggtcca aagttgaata ttgtaaaaat tgatgccggc
     5161 aaacagactg atatcatgaa acaaatgaat ttacccgcta ttcccgtatt tattatttat
     5221 aaaaacggac aggaggtatt tagaaaaaat ggaatagttg cacaaagtga ttttgatgct
     5281 gctattaaac cgctattata attttaaaat taatggccaa tataaaagcc ggagatgtaa
     5341 agtaacactc cggctttttc aatcaagggt attgggtaat taacggctgc tttttaaaaa
     5401 ttctacaatt ttttcccttt ctgcctgtgt aattaatgct cttgtttgca tgtgcatacc
     5461 tatggtttcc cattgctctg ccgaaaacga tgcaggagat ggtgtgttat ggcagcgctg
     5521 gcaattttct gcccataact gtgcgcccga tttggctgca actgctttgg taggtgcaca
     5581 accattgata gataatatgc ctgttattgc aaaaataaga acgagtgcca gcgtaatagt
     5641 atggagtggt tgataacgtt tcatcttttt aaattttaaa gttgaataga gaattgcaga
     5701 taaaatgtat tggtattggt agtgccattg tatgcgccta ataatttact ggcagtactg
     5761 ttgccggtat aagtttcgta agtggctttt acaacagttc tccaggttaa ccaataatct
     5821 aatcctacag caattgaatg ctggttggca ccaaaagtag agttgccggg taaattataa
     5881 ctggtatacc tgcctgcaat ttcaaaattt tttagaaagt tattggcttc agtgggtcgg
     5941 atagaacatt gtacaaaccc ggctgtagta tgattgttga atgaataact ttgtgtactg
     6001 tcgtttggat tcacataatt ctcattacta atattttgta tgttgtactg agccttaaca
     6061 tttactaaaa cagggttgaa ggttttaaca tagtttaaat caaacgcata catattgcct
     6121 gttgcatttt ggtagggcga acccagatct cctactttac caaacatgcc cgatacccca
     6181 atttctaatg atgaattaga aaacggtaac cagccaattc ttgcagtaat ggttttatta
     6241 ttgttattat ctacaatatt gccactggtt aatgtaccat tacccaataa ctgactgcca
     6301 ttgcttaatg ctacatcata gttcagtttc atgctgccta aaggcaaccc tccttctact
     6361 tccacaccat aatcagtagg cgtcatatct gcaataccca tggggtcggt agctaatttg
     6421 tcaatccatc cggcagcttc tcttttggca taggtaccaa aaggcaatac caaatatcct
     6481 gctcttataa taatattggg tgccgcaaaa taagatacat ctgcccagtt aacacccaag
     6541 ccattattac taaacgaagg ctcaaattct aataaaaact tttttccatg gcgccataaa
     6601 aacatggggc taaattcgta atgatcagca tctgctaaac tgttcgtttt agaaatagcg
     6661 ctaacaccac ccaatgtatt ggtgcttttg ctggcagcaa atccaaaagt ggttaatcct
     6721 gctaccataa aatggtcatt gcccggtttc tgataattag cttgttgttc caatgcattc
     6781 aatctgtcta gaacggttga gtctaaccca ccgctggttt gggcaatcaa atggggaaat
     6841 gtaccaccca tagcaagggc tatcaatccc attaatttat aaattttatg tttcatttct
     6901 tagcgtttta aggtgataga attcatggtt atcttatctt ttagccagag aacggatgta
     6961 attcactaac atccaccgtt gcgtatcggt taatgcttgt ttataagagg gcataggtgt
     7021 atgtccttcc gacattttcc aatacaaagc accatctgtt tctttttgaa cggcagcaga
     7081 agtatggtct gcgggtttgg gttttaaggc cgcggcagct atgccatctc cttttccatt
     7141 attgccatga caagggccac agttagtgat gtataatttt tttgcttctt ttaaaaccga
     7201 tgtattccca gctaatggat tcttgagttg attggctgat gccggtgcat tccaggtact
     7261 ggtttgtgcc tgcgatatgg ctggaaataa cagtgctgca gatacgatgc agaaaactgt
     7321 aattatattt ttctttgtcc gttttgttga agcttgctgt ttcatgataa actgttttgt
     7381 ttccacaaag gtttgctatc tgctacccgg cgaatatgat atttgttagc tttttaaatt
     7441 ataaggaaat tttaatgtaa taggaagatt tgatttttcg ttttttctgc tgcttgtttt
     7501 ctaattgttt taaaacttta cagctttatg gtatcattat attttttgtg caatcgttcg
     7561 gcctgtcacc aaaaagcatg aatttgaata gaaatgttat ctggcaaaat atcttttttt
     7621 aaacaccggt tttttcaatt aaaaaaaatt atctttcaaa aaaatttcta tggaaacttt
     7681 tatttctttt tggtggttaa ttgtactgct catcattctt ttcaccggaa tggtttcagt
     7741 tacacagggt aatatcactg tgttaacaat gtttgggaaa tacagaagaa tcttaaggcc
     7801 gggattaaat tttaagattc ctgttttcga acagatatat aaagtgatta gtatacaaaa
     7861 tcgctctgtt gaactggagt ttcaagcagt tacggttgat caggccaatg tatatttcaa
     7921 gagtatgcta ctctactccg taattaatgc cgaggaagaa accattaaaa aagtagcatt
     7981 caaattcatt agtgataaag atttgatgca ggcgcttatc cgcactgttg aaggctctat
     8041 ccgcgcttat gtagctacaa aaaagcaggc cgaaatttta ttgctgcgca gagaaatagt
     8101 ggagtatgta aaagcgcaaa ttgatcattc gttagaagaa tggggctatc atttacaaga
     8161 cttgcaaatc aacgatatta cttttgataa agccgttatg gaaagtatga gtaaggtagt
     8221 ggccagcaac aatttaaaag cggctgccga aaatgaaggg caggcgttac tcattaccaa
     8281 aaccaaagcg gcagaagccg agggcaatgc cattaaaatt tctgcagagg ccgagaaaga
     8341 agctgctcgt ttaagagggc agggggttgc attatttagg gaagaagtag caaaaggaat
     8401 gagccaggcc gcagaacaaa tgaaacaagc caatttagat accaacgtta ttttattcag
     8461 tatgtggaca gaagccatta aaaactttgc tgaggtaagc aatggcaatg ttattttttt
     8521 agatggcagc cccgagggga tggataaaaa tatgcaacaa attaaagcca tgctgcaaat
     8581 gaagaccaat aagtcctaaa tgttgccatc accttatctg gcactgaact tgctgtaagc
     8641 tcaggttccc aaatgtgtaa aagctttgct aaaacgcaaa ggctgcacaa ttttatgcac
     8701 aagtatcctg ttaagtttgt ttagcattta ctttagtgtt accataaaaa attatcagca
     8761 tgtttcattt gcttcaggtt gctgcaacac ccattgcaga tacattacat aaagccgcta
     8821 cagccattcc tccggtagaa gaaaaaattt ctatgtggga tatgctgcag aaaggaggtt
     8881 ttatcatgta tcctttgtat tttctgttgg tgttggcgct atttttcttt tttgagcggc
     8941 tcattgccat tcgtaaagcc tctaaaattg aacccaattt tatgagtatt atacgtgata
     9001 atattcttac cggcaacatt agtgctgccc gtagtctggc aaaaaatacg cccaatccgg
     9061 tagccaaaat gatcgataaa ggtttacaac gcattggtaa acccatcgat gccattgaaa
     9121 aaagtatgga aaatgtaggt aaattagaaa tgtacaatat ggaacgcaac ttatctgttt
     9181 tgtcgctgat agcaggtatt gcccccatgt ttggattttt aggaaccatt gtaggaatgg
     9241 tacaattgtt ttatggtatt gcctcaaccg gagaatatac gctgaatacc attgccgggg
     9301 gtatttatac taaaatggta accagtgcta caggattaat tattggttta atggcttatg
     9361 tagcatacaa ttatttaagc acacaaatag ataaaaccgc caataaaatg gaagtggcca
     9421 gtgcagagtt tattgatata ttgcaggaac caaccaaata aaagttgaga atgattttgt
     9481 taccagctgc agaactttgg gcatcgcctg ttgcgtcgca cacggcaact gcagtaaagg
     9541 aatcagcttt ttaatcataa ataaccgttt ttatactcat gaacatacgc cagggaatca
     9601 gaaaacgaca tgcagaagtg cacaccggtg ctttaaacga tatattgttt attctgttac
     9661 tgtttttttt aattgtttct actttggcca atcccaatgt aataaaagta gccaacccca
     9721 aagcaaaaag cgataccaaa gccaaacaaa ctgttgtaat tacagtggat aaagatcaaa
     9781 atatctacat tggacaaaaa ttagtgccat ttgatcagtt agaatcacaa ttacaggcct
     9841 ttttagccaa agaaactgat aaaccttcgg tagtaattaa tggcgatagt acttcacatt
     9901 taggtactgc cataaaggta atgcaggtaa tcaaaaagtt aggcgctaca ccggttgtgg
     9961 cagttgataa taatggtgtt caatagatta tcaaagcgca tcaactttta ggtaccaccc
    10021 tgtcttttac ataagttatt tgcgttttgc catgtgcctt cggcttacca tcttctccta
    10081 agttcacaaa tactaattta tcaatcgtca atatttgttc acgggttaat ttattgcgta
    10141 cctcgcagcg catggtgata gaggttttgc caaattcggt tgcaataatg ccaatctcaa
    10201 taatatcgcc ttgtttaggt gcatttacaa aattaatttc tgaaatatac tttgtaacta
    10261 ctttcgcgtt ttctaattgt ataatggcat aaatcacggc ttcttcatca atccattgta
    10321 ataatctgcc gccaaacaaa gtatgattcg gatttaaatc ctccggtttt acccattttc
    10381 gggtatgaaa attcatttca tctgttgcca tatcgtatta attattatgt tgtaataggc
    10441 tgtatcaaat cccatttatt gccatataaa tcttcaaata ccaatatagt accgtaaggt
    10501 tgaacttccg gtgcgtgaat aatatttaca ttttgctgtt gtaaatttgt ataatcacgt
    10561 tgtatattat ccgtatgcaa aaataaaaat accctgccac cgctttgctt accaatacat
    10621 ttctcctgtt cctcactcgc agctttggct aataataacc tgcatccttt actgccgggt
    10681 ggcgctatca ccacccatct tttaggttct gttaaaactg tatcttctat taaagtaaac
    10741 tgtaattttt gggtataaaa ggcaatggct tcatcataat cacgtactag caaagccatt
    10801 tgtacgattt cctgtttcat ttctttctca tttaatcctg ctcatttatt ctaaatctcc
    10861 caatcatatt aaaaattgca tcaagcctaa ttacgaacgg gtttccctgt ttttaataca
    10921 ctttgtatac gctctaatgt tttcttttca ccacataaac ttaaaaatgc ttcgcgttct
    10981 aagtctaata aatattgttc agatacctgg gtgggggcac ttaaatcgcc accgcacatc
    11041 acatgtgcca atttggtggc taccagggca tcatgatcgg ttacataacc gccacgcttc
    11101 atggcattga tacctaccaa cagggcaccc aaagctgaac gacctaaaac ggtaatgtct
    11161 tttcgttggg taggcatggt atagccggca tcatataaat caatcactgc ttttttagca
    11221 gctgcaattc ttctgtcggg gtttaatagt atggcatctc tgtcttttct gagtatgccc
    11281 attttatagg cttcaaaagc actggtagct actttagcag ttgcaatggt taaaaaacgt
    11341 tcttttaaag tatttaattc cggttcatct ttgtgtagtt catctgaggc acgcaataca
    11401 aattctttgg tgccgccacc tccgggtatc aatccaacac ctaattcaac caacccaata
    11461 tatgtttcag ctgctgcaca cactttatca gcatgcaggt ttaattcgca gccgccacct
    11521 aaagccaatc catgcggtgc agctacaacc ggaacagcag aatacctaac ccgcatcatc
    11581 gtattttgaa acatacggat ggccatatcc aattcctcat attcctgttc aatagccaac
    11641 ataaaaatca ttcctacatt ggctcctgca ctgaaattgg ggtcggggtt agcaatcacc
    11701 aatcctttaa atttatcttc tgcaacggta atggattgct gtatgccttc taatacttcg
    11761 ctgccaatac tattcatttt ggtactccat tctaatgctg ccacatcatt gccaatatca
    11821 tataatttac agccactgtt tttccagata agtccgtcgg taaaattgct taacacaata
    11881 aaactatcct cacccggcat aaaacgatag gctttaatgg gtacatcata aaacttcttc
    11941 tttccttttt ccaaagcata gaaggatgtt ttacctgctg ccagcatttc ctcaacccaa
    12001 tgcgcaacct gatagccggc caatttcatt tcatgcactg ttttggctac tcccagtaaa
    12061 tcccatgttt caaaagcgcc tatttcccag ccaaagcctg ctttcattgc atcgtcaatc
    12121 cggtacagtt catctgaaat ttcaggaaca cgataagaga tatatgaaaa cagcgcataa
    12181 tgaaaacttc ggtaaaaatt ccctgctgta tcgggcgatt gctgcaacag tttaattcgt
    12241 tctttcagat cttctatggg tttggcggct tctaatgctg caaattttgg tttttgcctt
    12301 gcttcatatt caaatgtttg cagattaatg acctgtattt cttttcctcc ggcacctttt
    12361 gtttttttga aaaagccttg tccggtttta tcgcctaaac ggttgtcttg taccattttt
    12421 tcgagccagg ccggtatttg gaatatgttt tttgcttcat cttccttaca attttctgct
    12481 acacctttgg ctacttttac cagggtgtct atacccacta catccgcagt tctaaaggtg
    12541 gccgatttgg ggcgaccaat tacagggccg gttaatgcat ctattgcatc aatgcttaaa
    12601 ccttgctgtt ccatgatgtg gaaaatactc atgatgctga aaaccccaat gcgattggca
    12661 ataaatgcgg gagtatcttt acacaatacg gttgtttttc ctaaatacaa atctccatac
    12721 tgtaaaagaa aatcaatcac ctcttgtttg gtatgtgcag ttggaataat ttccagtaac
    12781 tttaaatagc ggggtggatt aaaaaaatgc gtaccgcaaa aatgttgttg aaaatcatcg
    12841 cttcttccgg ctgccattaa atgtatgggt atgcccgatg tgttagaagt gattaacgta
    12901 cccggccttc tgaacttctc tacttcagca aatatttgtt gttttatgtc taaccgttcc
    12961 acaactactt caataatcca atcggcagtg gcaatatctt tcatattatc ggtaaagttg
    13021 cctgttgtaa tttttttggc tacatctggt gtaaataccg gtgaggggtt actctttaat
    13081 gcagtttgta aagcatcatt taccaatttg tttcttacag tggggttgtt gctttcaccg
    13141 gtatctttac tcagcatatc taataacaat acttcaacac ctgttcctgc aaaatgacag
    13201 gcaatgcgtg aacccataat gccgcttcct aaaacaacaa cttttttaat aatacgtttc
    13261 atgtgtttgt atttattaat tttagtcata taaaatagta caaatcatca tactttggtg
    13321 cgtagtgatt gtattttgac tatttcctgt atatgtttta ccatttgcaa attgcctgca
    13381 aataccccgt gcaatttttt gttgctttga ttccatcttc accaggcaat tgcatgtttc
    13441 attcaaacca tttgccattt cagaaaaagt aaaatacctt ttcaaaaaaa tggataaaat
    13501 gatgtgatgt ttaatttttg aactgagcat caaagctaaa taaaaaatag ttagctatgc
    13561 aactaatttt agtgaaattc tatcgctttt agcaaagcat tagagcaggt gttatggtaa
    13621 acggcttctt ctttccatta attcacgcca ggtggttaaa ataatacctt tttgttgtat
    13681 gtattgtctt aaacggggat caagcatggc taataaatcg ccgcggcgtg tggggccgct
    13741 gtcagatata tatttgaatt gtggggtagt agtcgtgcaa tgcataatta ccatggtaat
    13801 gccgggttgc agactatcga atgcagctat ataacgattc gttctgtagg cttgcaaaag
    13861 gctatcgttt tgtaatgtat ttgttgggtt tacccaatca tagctttcat tgtacaaatc
    13921 atctaaaacg ggtaagccgg ctttccataa taaattaccc atgaaatgca tttgtgccat
    13981 taattgttgc gatgcatgca tttgcagggc aatcagggta gcgtgtccgc cgggcaacat
    14041 caccgcaata tggttcttta tacccaattg aatatattgt tctgcaaaag caggtgtggc
    14101 caataaggtg cccatgtgtg tatctacatg ggtgggtgta aagcccattg ttaaagctct
    14161 ttgcagttgt gcattgattt cagtagctac ttccgcggca ctggcatgct gtactacatc
    14221 ggtcacattg ggccataaac agccctgctg atctaccagt cccggtgtag caggtttgcc
    14281 gctgagcggt ccccaacgat aatttttcca ttcagcggtt aaggttaaat gcaacccggc
    14341 atctatctgt ggatgttctt ttaaaaattg tacaaatccg ggcacccatg agcagggcat
    14401 cattacactg gttgaagtgg ccaccccttt ggttaatgct aatatggcac cttcattcga
    14461 ttcatagctc atgccggcat catctacatg taatatcacc acttttgctc ctttgggaaa
    14521 tcctaatttt tcggcataag tactgtctgt tgcctttgct gtaacaatta aaccgatgca
    14581 tacggccaat agcaacattt tttttcgggt atgcttgtat acatgtgtga atagaatagc
    14641 ttgcatggtt gtttttattt ttttaatgat gcaattaagt taagtaagtt tcagattcct
    14701 gcactgtttt ttgcggtatt tatttctatt gcaaaatccg atgctattga aaaatggagt
    14761 gcattatact ttactatcaa attttgatac tttttttgct ggatgggtgc ccttttttaa
    14821 ttctgcttta atctgcaaaa taaaatgggt agctttttta agaattgcag caaaaatcat
    14881 tactttcaaa cacccgaatc aaacattaaa atcttaccat attatgggcg aattacaaat
    14941 taaaaaagaa gcaaaaaagt acgatgcaat tattattggc tccggtgccg gtggtggcat
    15001 ggcggcttat gtgctggcca atgcaggctt aaaagtatgt ttattagaag ccggacccaa
    15061 ttacgatccg gccattaatt ctgatcagtt gaaaaatcca tgggagtcac cccggcgtgg
    15121 cgccagcacc aagtttcgtc cttttggcga ttttgacggt tgttactggg gttgggaaat
    15181 agatggtgag ccctataccc atgctaatgg taccaaatgg gagtggtggc gtgccagaat
    15241 ggtaggtggc cgcaccaacc ac
//
