LOCUS       c00002_NZ_JACI..       14188 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JACICA010000002.1 Alloprevotella rava strain DSM 22548
            Ga0373290_02, whole genome shotgun sequence.
ACCESSION   c00002_NZ_JACI..
VERSION     c00002_NZ_JACI..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:51:35
            Original ID  :: NZ_JACICA010000002.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 389859
            Orig. end    :: 404047
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14188
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[399859:402996]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13137
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..14188
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14188
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             578..835
                     /locus_tag="ctg2_317"
                     /transl_table=11
                     /translation="MEKKHVFAFDRTNFILLAIGMAIVILGMILMSGKGSDATHFNPDI
                     FSAMRIKVAPVVCLFGYLFMIVGIIRRPRDKEDNATSVEK"
     CDS             892..1737
                     /locus_tag="ctg2_318"
                     /transl_table=11
                     /translation="MNWFEAIVLSIVEGLTEFLPVSSTGHMIITEGLLHMESTPFVKAF
                     TVIIQFGAILSVVCLYWRRFFNPPVEAGKNTSWWGRIWPFYLKLIVGVLPAVVVGLKLG
                     DFIDENLGSVNTVAAMLIIGGVFMLYCDKLFNKGSEQTPLTYKRALMVGLYQCIAALLP
                     GTSRSMATIVGGMQQKLTRKAAAEFSFFLAVPTMFGATCKKVYDLLKDGTGDALLQGNH
                     LTLLLTGNIIAFLVAILAIKFFLNYVTKYGFKAFGWYRIIVGLLIFGMALCGYPLTMAD
                     "
     CDS             1807..2592
                     /locus_tag="ctg2_319"
                     /transl_table=11
                     /translation="LNFFDGKILAFDKPYRATSFSEVGHLRWLLTKRMTGHKIRVGHAG
                     TLDPLATGTLIICTGRATRIIESLQTHTKEYIAEVRLGETTASYDLEHPVDQTYPTEHI
                     TEAMVREVLHSLEGDIMQIPPAYSACKINGDRAYQLARNGEEVPLKAKSVRVEEIELLE
                     MRLPDYLKIRVVCGKGTYIRSIGRDIGERLGSGAHLLSLRRTRVGDIRVEDCWKMEDFE
                     RWLESQTLETEPPSGPIPSEFPFLTPANCLGEEPLTTLG"
     CDS             2676..3740
                     /locus_tag="ctg2_320"
                     /transl_table=11
                     /translation="MKLSQFKFDLPQEQIAPDPNPHRDDCRMMVLHRQTGEIEHKQFGD
                     ILSYFQPHDLFVFNDTKVFPARLYGRKEKTGARIEVFLLRELNHEQHFWDVLVDPARKI
                     RIGNKLYFGEAEDIVAEVIDNTTSRGRTLRFLYEGEHEDFKRSLYALGEAPIPRFTGHV
                     STPENRESDIENFQCIFARHEGAVTAPTAGMHFSKILMKKMEIQDINTAYLTLHCGLGN
                     FRSTDVEDLTKHKMESEEMIVGAECCAAVNKAKEEGRHILAVGTTVQRALEVCVGPDRR
                     IREFEGHTNKFIFPPYDFLVADSMVVNFHLPESTMVMLTTAFGGYEQTMAAYEEAIKEG
                     YMFGPFGDAMLIVD"
     CDS             3774..4685
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_321"
                     /sec_met_domain="Acetyltransf_1 (E-value: 4.4e-12,
                     bitscore: 40.7, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTVYIGLGSNLGNRRENLERAVTLLEQRVGTLLRLSAFWETAPV
                     GFESEHPFLNAAAAFCTSLSPAELLPLTQQIEREMGRTQKSLKGVYHDRIIDIDLLCSD
                     GESVHTAELQLPHPHLSERRFVLEPLAEIAPELWIDGKGYVSDLLDKLNGHNIRPLTPA
                     DTPLFEQFNALFPQLSKQVRPLTAEEIIALLQRPDTWVYVAFTPEGRLVGTITLCLAAS
                     PTGTKGWAEDLVVDTSVRGAGFGKALILRSAREAFRHGADSVNFTSRPSRTAANNLYVS
                     LGFEQRETNVYRCKQYDSLKLH"
     CDS             4696..5277
                     /locus_tag="ctg2_322"
                     /transl_table=11
                     /translation="MPHTSKQSTLFIKNMVCRRCIMAVENILQRNAIEVQSVSLGEVVL
                     STPISPEMREKLKAEFEAVGFELIGDRRSQLIENIKRETMTYARAEDGLSHLRLSDFLQ
                     ERLHLDYHYLSDLFSAVEGQTLEKFFIAHRIERVKELLVYNELPLSDIAVRLGYSSTAY
                     LSTQFKKQTGLTPTRFKQLTSQRRCALDEL"
     CDS             5305..6183
                     /locus_tag="ctg2_323"
                     /transl_table=11
                     /translation="MKNLLYKFGFGCVWLFSCLPLGLLYVLSDLLFFLVRYVVRYRLGV
                     VRRNVARSFPEKTPAERNRIINGFYHYFCDYIFETLKLYSMSVSEIRRRMVFTNIPEVE
                     ALLHDHDFVFIYLGHYGNWEWVSSLGVWFSESIYPCQLYKPIRNHFLDQLFLKLRRHFR
                     SHNIDKNLVLREILRLKSEGKKVVCGFISDQSPKPVDIHEWVDFLHQDTPCFTGAERIG
                     KKLNAAFVYLDVERKSRGHYEATFELMSSTPREIPDWQLTADFMQRLETTIRRQPEIWL
                     WSHKRWKHQRS"
     CDS             6325..6594
                     /locus_tag="ctg2_324"
                     /transl_table=11
                     /translation="MYLDSAKKQEIFGKYGKSNSDTGSCESQIALFSYRIAHLTEHVKA
                     NRKDHSTERALVMLVGKRRRLLNYLKDRDIERYRAIIKALGLRK"
     CDS             6677..7345
                     /locus_tag="ctg2_325"
                     /transl_table=11
                     /translation="MENSQLIEALRLCPLFKGFSSQEMDELLSQIHYKLVDYSPKDIYV
                     LAGMPCRHADIVVSGQMTARMVGLSGKFVEVDHRGPGSLMAPALIFVPNSEMPVSVETE
                     EPTRIFRMTPAELKRLIDSNERIRTNFILVLSQINYFLTQKMRVLALFSVREKVVSLLK
                     QIASKQQSEVITLTRSRQQIADSFGIQKFSLLRVLATLEEEGAIRVEGKTIRIVDRSKL
                     "
     CDS             7517..9166
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Prismane"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_326"
                     /sec_met_domain="Prismane (E-value: 1e-168, bitscore:
                     556.5, seeds: 159, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESQMFCYQCQETVKGTGCTLRGVCGKLPQTSTYMDLLIAVARGV
                     GSIDHLLRTAGVTTEQAVGDFIVDALFATISCANFDDESIMAKVDTGLLLKQQLIGLAE
                     QNGVELPNWAEVTWTGSRKDYYAEGLRQTILRIPNEDIRSMKEIVVLGLKGIAAYYEHA
                     SRLGHRDNSLIAFMSEALYDITNPDATADALYTLVLRVGEYGVPAMALLDKANTAAYGN
                     PEISRVNIGVGNRPGILITGHDLRDLKELLEQTEGTGIDVYTHGEMLPGNYYPELKKYK
                     HLVGNYGNAWWRQKEEFSTFNGPIVFTTNCIVPPLPNANYKDRVFTTNSTGYPGWKHIL
                     PDANGHKDFSEVIEMAKQCQAPTEIEHGEIVGGFAHAQVFALADKIVEAVKSGAIRKFF
                     VMSGCDGRMKNRNYYTEFAEALPKDCVILTSGCAKYKYNKLNLGDINGIPRVLDAGQCN
                     DSYSWALVALKLKEIFGAADINDLPIVFNIAWYEQKAVIVLLSLLYLGVRNIHVGPTLP
                     AFMSENVRKILIEKFGLGTISTVDEDLQKFLA"
     CDS             complement(9129..9581)
                     /locus_tag="ctg2_327"
                     /transl_table=11
                     /translation="MRLLAIRARILLTCFSAFRNDSSVLYFKSPKKLRFPTKMEIFSFI
                     LFVRTIRASANFLIAPTDTISPSADSFIVAMRERLRQSQQKMARWILRHSRKKESKKFV
                     DIFSPRIFAKEANGHEKGISPLLTYIRIGRGEIEIRLRTSGDLHRR"
     CDS             9860..9949
                     /locus_tag="ctg2_328"
                     /transl_table=11
                     /translation="MCNFAVPLEALYLVSDTFVIEPCSGMTLV"
     CDS             10001..12247
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_329"
                     /sec_met_domain="Gly_radical (E-value: 7e-38, bitscore:
                     123.8, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 1.2e-257, bitscore:
                     850.5, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNEWRGFAEGQWTSEVDLRDFIQKNYTPYNGAEDFLAGPTEATD
                     KLWGMLKELQKQERAKDGVLDMETEVVSSLTAYPPSYIGEGTKELEKVVGLQTDKPLKR
                     AFMPYGGIKMAEQACTTYGYQPSQQLHDIFTKYVKTHNDGVFDAYTTEMRRVRHNHILT
                     GLPDSYGRGRIVGDYRRVALYGIDFLVAEKRADLENMGDRDMIDEVVRLREEVSMQIRA
                     LNGLKEMAAEYGFDISRPAANGREAVQWLYFGYLGAIKTQNGAAMSVGRISTFLDIYFE
                     RDFKEGTLTESDAQELIDHLVMKFRMVKFARIPSYNQLFSGDPVWATLEVAGMGMDGRS
                     MVTKNDFRFLHTLENMGPSPEPNLTVLYSSRLPQGFKHYAAKISVVTSSIQYENDDVMR
                     PVWGDDYSICCCVSATQTGKEMQFFGARANLAKCLLYAINGGVDTKSREQCGPAYRPIT
                     SDVITYEEFMPRFEDMMEWLAGVYVKTLNLIHYMHDKYFYEAAEMALIDTNVRRTFATG
                     IAGFSHVVDSICAIKYAKVTAVRDEEGFAIEYKTEGDYPRYGNDDERADEIAVWLLKTF
                     MKKIRKFHTYRNSEATTSILTITSNVVYGKYTGAMPDGRAAGTPLAPGANPSYGAEKNG
                     LLASLNSVAKLPYEYALDGISNTQTINPGALGQNDEERSNTLVGVMDGYFDRGAHHLNV
                     NVFGVDKLRDAMEHPEKEEYANFTIRVSGYAVKFIDLTREQQLDVIARHAHENL"
     CDS             12412..13137
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 81.7;
                     E-value: 2e-25)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_330"
                     /sec_met_domain="Radical_SAM (E-value: 4.3e-34, bitscore:
                     112.7, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGHIHSTESFGSVDGPGIRFIIFFQGCGMRCRYCQNPDTWEVGQ
                     GQEMTAEELLAKAERYRSYWGKDGGITVSGGEPLLQIDFLTELFQKAKERGIHTCIDTC
                     GQPFTRREPFFSKFQKLMDYTDLLLLDIKHINSLEHQKLTRHPNENILDCARYLSEIGK
                     PIWVRHVLVPGITDNDDYLTELRHFLRPLQNIQRIDVLPYHSLGLFKWKQRNIPYTLEG
                     VPSPTAERIENARRILTQD"
     CDS             complement(13303..13449)
                     /locus_tag="ctg2_331"
                     /transl_table=11
                     /translation="MQLIIFSDPLYKKFGDIFGSSSEDINNGFFTLLKGEKTSVKFLKS
                     FTE"
     CDS             complement(13819..14001)
                     /locus_tag="ctg2_332"
                     /transl_table=11
                     /translation="MRIETLFSQLTDQFLVIRNYAKITNGLFDRIISKISALTVLQYVN
                     FINNKPIGRIKYALN"
ORIGIN
        1 ccgagtttga tgtgtatttg aaagcagaat acgccaactt ggacagccta aaacgttttg
       61 tgcccatctt gaagcaacgc gctggcgtgg ccgatgtggt gtatcccatc gaggagatgc
      121 gcagtcttga caagacgatt ccaacggtga gccttgtttt gctcgtgctg gccgtactct
      181 tagcgtttgt ttcctttgcg cttatcaaca acacgatacg catgagcatc tatgcccgcc
      241 gcttcaccat tcacacgatg aagcttgtgg gagctcgctg gagtttcatc cgccgtccct
      301 ttatgtggaa agcctttgcg ataggtctga tttcatccct tattgccagt gggcttatcg
      361 gcgtgggcat atatctgctg tggatgcagg atctctacat tggtagtctg attacgccaa
      421 tcattgtagg ctctacgata ggcactatct ttgtgagcgg cttggtaatg accttggcgt
      481 gtgcctacat ttgcgtgaat cgctatctgc gtatgagtga agggcaaatg tatctcaaat
      541 aaattttcgg aaaaatcaaa aaaacatatt tccaacaatg gaaaagaaac acgtatttgc
      601 gtttgatcgc accaatttca ttctgttagc catcggtatg gctatcgtta tcttgggcat
      661 gatactcatg tctggaaaag gctctgatgc cacacatttc aatcccgata ttttcagcgc
      721 aatgcgcatc aaggtagctc ccgttgtttg cctcttcggc tatctcttta tgattgtggg
      781 catcatccgc cgtccacgcg acaaggagga taatgctact tcagtggaga agtaaacacg
      841 ttaggagcta tcattatgtt cgacatatct ctacttacag cttcggccga tatgaattgg
      901 ttcgaagcta ttgtgcttag tattgttgag ggtttgacgg agtttttgcc cgtttcctca
      961 acaggccaca tgattatcac ggaggggctc ttacatatgg agagcacacc gtttgttaaa
     1021 gcctttaccg ttattattca gtttggcgca atcttgagcg tcgtatgcct ctattggcgc
     1081 cgcttcttca acccgcccgt tgaagcaggg aaaaacacct cttggtgggg gagaatctgg
     1141 ccgttctatt tgaaactcat cgtgggcgta cttcccgcag ttgtcgtggg gctcaaattg
     1201 ggcgatttca tcgatgaaaa tctcggtagt gtaaataccg ttgcggcgat gctcatcatt
     1261 ggcggtgtgt ttatgcttta ttgcgacaaa cttttcaata aaggtagcga acaaacgccg
     1321 ctcacctata agcgcgcctt gatggtgggt ctctatcagt gtatcgccgc gttgctacct
     1381 ggcacctctc gttcgatggc gaccatcgtg ggcggtatgc aacagaagtt gacgcgcaaa
     1441 gcagccgccg aattttcgtt cttcctcgcc gttccaacga tgtttggagc aacgtgtaag
     1501 aaagtttacg acctcctgaa agacggaact ggcgatgctc tcctgcaggg taatcatctc
     1561 acgctcttgc tgacgggtaa tatcatcgcc ttccttgttg ctattctggc cattaagttc
     1621 ttcctcaact atgtgacgaa gtacggtttc aaagccttcg gttggtatcg catcattgtg
     1681 ggattgctta tcttcggaat ggctctctgc ggctatccgc ttacgatggc cgattagaga
     1741 atagcctctt cggagcattt ctcaaaagta tattagcaca ttattattcc ttattatatt
     1801 tctgccttga acttcttcga cggaaaaatt ttagctttcg acaagcctta cagagccacc
     1861 tctttcagtg aggtggggca tcttcgctgg ttgctgacta agcgcatgac aggacataaa
     1921 atccgcgtgg gtcatgctgg tacgctcgat cccttagcca ctggtacact cattatttgt
     1981 accggtagag ccacgcgaat catcgagtcg ttgcaaactc ataccaaaga atacattgct
     2041 gaggtgcgtt tgggggaaac aacggccagc tacgatctgg aacatcccgt ggatcagacc
     2101 tatcccacag aacacatcac cgaagctatg gtgcgcgaag tgctgcatag tctcgagggc
     2161 gatattatgc aaattccccc cgcttattct gcttgtaaaa tcaatggaga tcgtgcctat
     2221 caactggcac gtaatggcga ggaagtgcct ctgaaagcca agtccgtccg tgtggaagaa
     2281 atagagcttt tagaaatgcg cctgcccgat tatctgaaaa tccgcgttgt ttgtgggaaa
     2341 ggcacttaca tccgttctat cggtcgcgac atcggcgagc gtctcggtag cggtgcacac
     2401 ctgctctcgc tgcgccgtac tcgtgtgggc gacatccgcg tggaagattg ctggaagatg
     2461 gaagacttcg agcgttggtt ggagagtcag actctcgaaa ccgagccgcc atcaggccca
     2521 ataccttccg aatttccttt ccttacgccc gccaattgtc tgggcgagga acccctcacc
     2581 actttaggtt aaaaacacac tcacaataat agaaataaaa ctcctgtccg taaccatgaa
     2641 gaagcgagca ggagaaaaac ataaacagaa aagatatgaa actctctcaa ttcaagttcg
     2701 acctccctca agagcagata gctccggatc cgaaccctca tcgcgacgat tgccgtatga
     2761 tggtgctcca ccgccaaacg ggagaaattg aacacaagca gttcggcgac attttgagct
     2821 actttcagcc ccacgacctt tttgttttca acgacacaaa ggtgtttccc gcccgcctct
     2881 atggacgtaa ggaaaaaaca ggagctcgca tcgaagtgtt tctgcttcgc gaattgaacc
     2941 atgagcaaca cttctgggac gtacttgtag atccagcgcg caaaatccgt atcggcaaca
     3001 aactctattt tggcgaagct gaggacatcg tggccgaagt tatcgacaac actaccagcc
     3061 gcggccgtac gcttcgtttc ctctacgagg gggaacacga agatttcaag cgttccctct
     3121 acgctctcgg cgaagctccc attcctcgtt tcactgggca cgttagcacc cccgagaatc
     3181 gagagtcgga catcgaaaac ttccagtgca tctttgctcg tcatgagggc gcggtgactg
     3241 cacctactgc cggtatgcac ttctccaaaa ttctgatgaa gaagatggag atacaagata
     3301 tcaacacggc ttaccttacg ctccattgcg gacttggcaa tttccgttcc acagacgttg
     3361 aagatttgac caaacacaag atggaaagcg aagagatgat agtgggcgcg gaatgctgcg
     3421 ccgctgtcaa taaagcaaag gaagagggac gccatatttt ggctgtcgga acaacggtac
     3481 aacgcgcttt ggaagtatgt gtggggccag accgccgcat ccgcgagttt gagggacata
     3541 ccaataagtt tatcttccca ccttatgact tccttgttgc cgactctatg gttgtcaatt
     3601 tccatttgcc cgaatccaca atggtcatgc tgactacggc gttcggcggc tacgaacaaa
     3661 cgatggcagc ctatgaggaa gccatcaaag aaggctacat gtttggtcct ttcggcgatg
     3721 caatgctgat tgtagactaa aagcagagca ccgcgtaaga catccacgag gctatgagta
     3781 ctgtctatat aggtctgggt tctaatctcg gcaaccgtcg ggagaacttg gagcgcgctg
     3841 tgacactctt agagcaacgg gtgggcacat tgctacgcct ttctgctttc tgggaaactg
     3901 ctcctgtagg ctttgaatca gaacatccgt ttctcaacgc tgcagctgcg ttctgcacct
     3961 cgctctctcc cgccgagtta ttgccactta cgcaacaaat tgagcgcgag atgggacgaa
     4021 cgcagaaaag cctcaaaggt gtgtatcacg accgtattat tgacatcgat cttctttgtt
     4081 ctgatggcga atccgtgcat acggcggagc tgcaactccc tcatcctcat ctctccgagc
     4141 ggcgttttgt tttagaacct ttggctgaaa tcgctcccga actttggatt gatggaaagg
     4201 ggtatgtgtc ggacttgctc gataagctga atggtcacaa catccgtcca ctcacgcctg
     4261 ccgatactcc tctcttcgaa cagttcaatg ccttgtttcc ccaactatcg aaacaagtgc
     4321 gccccctcac tgccgaagaa atcatagctc ttttgcaacg tcccgacaca tgggtttatg
     4381 tagcctttac tcccgagggg cggcttgttg gaactatcac gctctgctta gccgcatccc
     4441 ccacaggcac aaaaggctgg gcggaggatt tggtagtaga cacctccgtg cgcggagctg
     4501 gctttggcaa agctctcatc ctgcgctctg ctcgcgaagc ctttcgtcat ggcgcggact
     4561 cggtcaattt cacctcgcgt ccttcgcgca ctgcggcaaa taatctctac gttagtttgg
     4621 gtttcgaaca gcgcgaaaca aatgtgtatc gttgcaagca atatgatagt ctgaagctgc
     4681 actaaatccc tccctatgcc tcacacctcc aagcaaagca cgcttttcat aaagaatatg
     4741 gtctgccgcc gctgcatcat ggctgtcgaa aacatcttgc agcgcaacgc cattgaggtg
     4801 caatccgtca gcttgggcga agtggtgctt tccaccccca tctcgcctga gatgcgagag
     4861 aaattaaaag cagagtttga ggcggtaggt tttgaactta tcggcgaccg ccgttcgcag
     4921 ctcatcgaga acatcaagcg ggaaacgatg acttatgcgc gagcagaaga cggtctttcc
     4981 caccttcggc tctctgattt tctgcaagaa cgcctacatc tcgactatca ttacctctcc
     5041 gatctctttt ctgctgtaga agggcaaacg ttggagaaat ttttcattgc ccatcgcatc
     5101 gaacgcgtca aggaacttct tgtctacaac gaactcccac tttccgacat tgccgtgcgc
     5161 ctcggctatt cctctacagc ttatctgagc acacagttca agaaacaaac aggacttacg
     5221 cccacgcgtt tcaagcaact cacgtcgcag cgccgctgtg cactcgatga gctttagccc
     5281 tcttttctca atccgcatca tgttatgaag aatcttctct ataagtttgg ttttggttgc
     5341 gtatggcttt tttcatgcct acctttaggg ctgctctacg ttctctccga cctcttattt
     5401 tttctcgttc gctatgtggt gcgctaccgc cttggcgtgg tgcgccgcaa tgttgcacgc
     5461 tcctttcccg agaagacgcc agcggagaga aaccgcatca tcaacggttt ctaccattat
     5521 ttctgcgact atatttttga aacgctcaag ctctattcca tgtctgtgag cgagatacgc
     5581 cggcgcatgg ttttcaccaa tattcccgag gtggaagccc tcctccacga ccacgacttt
     5641 gtcttcattt atctcggcca ttatggcaac tgggaatggg tttcttccct cggtgtctgg
     5701 tttagtgaaa gcatttatcc gtgccaactt tacaaaccca tccgtaatca cttcctcgac
     5761 caactctttc tgaagctccg ccgccatttc cgttctcaca acattgataa gaacctcgtt
     5821 ctgcgcgaga ttctccgcct caaatcggaa gggaaaaagg tggtttgtgg ctttatctcc
     5881 gatcagagtc ccaagcccgt cgacatccac gaatgggtag attttctcca tcaggacacg
     5941 ccctgcttca caggtgcgga gcgaattggc aaaaaactca atgccgcttt cgtctacctt
     6001 gatgtagagc ggaaaagtcg cggtcactat gaagccacct ttgaactgat gagcagcacc
     6061 cctcgcgaaa ttcccgattg gcagctcacg gccgatttca tgcaacgctt agaaaccact
     6121 atccgccgcc aacccgaaat ttggctttgg agccacaagc gttggaagca ccaacgctca
     6181 taaatcatac ttttgagcag catagagata agaaaatcaa ttatttcgcc gtatttttct
     6241 tgttgctcca ataattttat ctaactttgc acccgctttc ctcggagagc accattataa
     6301 tatcatttaa tttcattaca aactatgtac ttagattctg ctaagaaaca agagatcttt
     6361 ggcaagtacg gaaagtctaa ctctgatact ggttcctgcg agagccagat tgcattgttt
     6421 tcataccgta ttgcccactt gacggaacat gtgaaggcca accgtaaaga tcatagtact
     6481 gaacgtgccc tcgttatgtt ggttggtaag cgtcgccgcc tcctcaatta tttgaaggat
     6541 cgcgacatcg agcgctaccg tgccattatc aaggctctcg gtcttcgcaa gtaattccga
     6601 tttcttgcac aaaagctttg aaacgtcact ccttgcgagc ggcgtttctt ttttttatcc
     6661 tattgttcaa tgcgatatgg aaaattctca actcattgag gctcttcgcc tctgtccttt
     6721 gttcaaaggg ttctccagtc aggaaatgga tgaacttctt tctcagattc attacaagct
     6781 ggtggactat tcaccaaagg atatatatgt gctggccggt atgccttgtc gccatgctga
     6841 catcgttgtc agcggacaga tgacagcccg catggtagga ctttcgggaa agtttgttga
     6901 agtggaccat cgaggaccag gtagtttgat ggctcctgct ctcatctttg tacccaatag
     6961 tgagatgccc gttagtgtgg aaaccgaaga acctacgcgc atttttcgta tgacgcctgc
     7021 cgaactcaaa cgtctcatcg acagcaacga gcgcatccgc accaatttca tcctcgttct
     7081 gtcacaaatc aattatttcc ttactcagaa gatgcgcgtg ctggcacttt tcagcgtgcg
     7141 cgaaaaagtg gtttctttgc tcaagcagat tgccagcaaa cagcagtcgg aggtcatcac
     7201 cctcacgcgc tctcgtcagc agattgccga ctcctttggc atacagaagt tctccctcct
     7261 ccgcgtctta gccacgctcg aagaggaagg agccatacgc gtagagggaa aaaccatccg
     7321 catcgtggac cgcagcaaac tctgatttgt ccgcctctta agtggcttat cgggcgtaag
     7381 ctggtgagcc atcaccttat ctcagtacta aaaaaactaa aattctacac gcagataaca
     7441 tttgttacca ttgcccggat gagggttccg tatttttgcg cccattaacg cataactatt
     7501 taaattattc tgaagtatgg aatctcaaat gttttgttat cagtgtcaag aaaccgtgaa
     7561 aggtacaggc tgtacgcttc gcggcgtgtg tggtaaactc ccacagacct ctacttatat
     7621 ggacctcctc attgccgttg ctcgcggtgt gggttctatc gatcatttgc tccgcactgc
     7681 tggcgtaacc actgagcagg ccgtgggcga tttcatcgtc gacgcgcttt ttgccactat
     7741 cagctgtgcc aatttcgatg atgaaagtat catggcaaag gtcgatacag gccttctcct
     7801 caagcaacaa ctcatcggct tggctgaaca aaacggtgtg gaactcccca actgggctga
     7861 agttacatgg actggtagcc gcaaggacta ttatgctgag ggactccgtc agaccattct
     7921 gcgcataccc aatgaggata tccgttctat gaaagaaatc gtagtgctcg gcctcaaagg
     7981 aatagcagcc tattatgaac acgcttcccg cttgggacat cgcgacaata gccttatcgc
     8041 atttatgagc gaagctcttt acgacatcac caaccccgat gccacggccg atgcgctcta
     8101 tacgctcgtg cttcgcgtgg gcgaatatgg tgttcctgct atggcgttgc tcgacaaggc
     8161 caacaccgct gcgtatggta atcccgaaat ctctcgtgtc aatatcggag tgggcaaccg
     8221 tcctggtatt ctcatcacgg ggcatgacct gcgcgacctc aaagaactcc tcgagcaaac
     8281 tgaagggacg ggcattgatg tctacaccca tggcgaaatg ctccctggca attactatcc
     8341 agaactcaag aaatataagc acctcgtggg taattatggc aacgcatggt ggcgtcaaaa
     8401 agaagaattc agtacgttca atggcccgat agtatttact accaactgca ttgtaccgcc
     8461 actgcccaac gccaattata aggatcgtgt tttcactacc aattccaccg gttatcctgg
     8521 ttggaaacac atcttgcccg atgctaacgg ccacaaggac ttctccgagg ttatcgagat
     8581 ggccaagcag tgccaagcac ctacggagat agagcacggc gagattgtag gtggttttgc
     8641 ccacgcccaa gtgttcgcct tggccgataa aatcgtggaa gctgtcaaga gtggtgctat
     8701 ccgcaaattc tttgtgatga gcggttgcga cggacgtatg aaaaaccgca actactacac
     8761 cgaatttgcc gaagcactcc ccaaagattg cgtgattctc accagcggct gtgccaagta
     8821 taaatacaac aagctcaacc ttggcgatat caacggtatt cctcgcgtgc tcgatgcagg
     8881 ccagtgtaac gactcctact cttgggcact ggtagctctc aaactgaaag agatttttgg
     8941 agcggccgat atcaacgacc tccccattgt gttcaacatc gcttggtatg agcagaaagc
     9001 tgtcatcgtg ttgctctcgc ttctctacct cggagtgcgc aacatccatg taggtccaac
     9061 gctccccgcc ttcatgtcgg agaatgtgcg taagattctc atcgagaagt ttggtttggg
     9121 caccatctct accgtcgatg aagatctcca gaagttctta gcctgatttc tatctcccct
     9181 ctgccaatcc taatataggt taacagaggg gagattcctt tttcgtgccc attcgcctct
     9241 ttcgcgaata ttcgtgggct aaaaatatca acgaatttct tactttcctt cttccgagaa
     9301 tgcctcaaaa tccatcgcgc catcttctgc tgagactggc gaagcctctc gcgcatcgct
     9361 acaataaagc tgtcggccga cgggcttatt gtgtcggttg gcgcaataag gaagttggcg
     9421 gatgccctta ttgtacggac gaagaggatg aagctaaaaa tctccatttt tgttggaaat
     9481 ctcagttttt taggactttt gaagtataga actgagctgt cattgcgaaa agcggagaag
     9541 caggtaagta gaatccgcgc gcggatggct aaaaggcgca ttttctcgcg caaaaagaaa
     9601 accgctcgat gtcaagtaat cgggcggttt tttatgcgta tttggggaat cgttctctcc
     9661 ctctcgctct ttatcgtctc ctacccacaa cgggggatac tgaatgcacc aataataaag
     9721 aatggttttg ctatcctaca aattgcaatt tgcaagtatc atttacagtg agcgcactac
     9781 cgcaaaaggg ttaaaatgaa tcagaacata ggaatgataa gctttattcc agataaaaat
     9841 agcacaaaag gtcctattaa tgtgtaattt tgcagtgccc ttggaagcgc tctaccttgt
     9901 gtcggataca tttgtgatcg agccatgcag cggcatgaca cttgtttaga gagctgggca
     9961 aaagcgaaaa catattacat aacccataac gacaacaatt atgagaaatg aatggagagg
    10021 ttttgctgaa ggacaatgga cttcagaagt agacctaaga gactttatcc agaaaaacta
    10081 cactccctat aacggtgcag aggacttcct tgctggccca acagaggcta ccgataagct
    10141 ttggggtatg ctcaaagaac tgcaaaagca ggagcgcgct aaagacggtg tactcgacat
    10201 ggaaaccgag gtggtttctt ctctcacggc ctatccccct tcttacattg gcgaaggcac
    10261 gaaggaactg gagaaagttg tgggcttgca aaccgacaag ccgctcaagc gtgctttcat
    10321 gccctacggt ggtatcaaaa tggccgagca ggcttgcacc acttacggct atcagccttc
    10381 tcaacaactc cacgatattt tcaccaaata tgtgaagaca cataacgatg gcgtgtttga
    10441 tgcttacacc acggagatgc gccgcgttcg ccacaatcat attcttacgg gtctgcccga
    10501 ctcttatggt cgtggccgca tcgtgggcga ctatcgccgc gtggctctct atggtatcga
    10561 cttcctggtg gctgaaaaaa gagccgactt ggaaaacatg ggcgaccgcg atatgatcga
    10621 cgaggtagtg cgtctgcgcg aggaagtatc tatgcagatt cgcgccctca atggtctcaa
    10681 ggaaatggcc gctgagtatg gtttcgacat ctcccgcccc gctgctaacg gccgcgaggc
    10741 agtgcagtgg ctctacttcg gctatctcgg tgccatcaag acacagaacg gtgctgctat
    10801 gtcagtgggc cgtatttcta cgttcctcga catctatttt gagcgcgact tcaaggaagg
    10861 cacgctgacg gagtccgatg ctcaggagct catcgaccac cttgtgatga agttccgcat
    10921 ggtgaagttc gcccgcattc cttcctacaa ccagctcttc agtggcgacc ccgtttgggc
    10981 tacgcttgag gtagcaggta tgggcatgga cggccgctcc atggtgacga agaacgactt
    11041 ccgtttcctc cacacgctgg agaacatggg tccttctccc gagcccaacc tcacggtgct
    11101 ctattcttca cgcctgccac agggtttcaa gcactatgct gctaagattt ctgtagtaac
    11161 cagttctatc cagtatgaga acgacgacgt gatgcgtcct gtttggggcg acgactacag
    11221 catctgctgc tgcgtgagtg ccactcaaac tggtaaggaa atgcagttct tcggcgcgcg
    11281 tgccaacttg gccaagtgtc ttctctatgc tatcaacggc ggtgtagaca ccaagagccg
    11341 cgagcagtgc ggtccagctt accgccccat cacgagcgac gtgattacct acgaagagtt
    11401 catgcctcgc tttgaagata tgatggaatg gttggcaggt gtttatgtga agacgctgaa
    11461 cctcatccat tacatgcacg ataagtattt ctacgaggct gctgagatgg cactcatcga
    11521 taccaacgtg cgccgaacct tcgcaacggg tatcgctggc tttagccacg tagtcgattc
    11581 tatctgtgct atcaaatatg ccaaggtaac ggctgtccgc gatgaggaag gcttcgctat
    11641 cgaatataag accgagggcg actatcctcg ctatggcaac gacgacgaac gtgctgacga
    11701 aatcgctgtt tggttgctca agacattcat gaagaagatt cgcaaattcc atacttaccg
    11761 taactcagag gctacaacga gcatcctgac cattacttct aacgtggttt acggtaaata
    11821 tactggtgca atgcctgatg gccgcgctgc cggcacgccg ttggctccag gtgccaaccc
    11881 ctcttacggt gcagaaaaga atggtttgct cgcttctctc aactctgtgg caaaactgcc
    11941 ttatgagtat gccctcgatg gtatttctaa cacgcagacc atcaatccgg gtgcactggg
    12001 acagaatgat gaggaacgct ccaacacgct ggttggcgta atggacggtt atttcgaccg
    12061 cggtgcgcac cacctcaacg tgaatgtctt tggtgtcgac aaactgcgcg atgctatgga
    12121 gcatcccgag aaggaagaat atgccaactt caccatccgt gtgagcggat atgcagtgaa
    12181 gttcatcgac ctcactcgcg agcagcagct cgacgttatt gcgcgccacg cacacgagaa
    12241 tttgtaaact aacagaaaag ggaaagtccc ttccatctcc ctcatgagag ggggtgtcca
    12301 gaacctcttg tttgagcctc caactgatcg gatagatcgg atgagttcga agcaaaactg
    12361 gacactcctc ttgatacgag agaggtggag ggggcttggc tttatcatta tatgacaggt
    12421 catattcatt ctacggaatc tttcggctcg gttgacggac caggcatccg tttcatcatt
    12481 ttttttcaag gttgtggtat gcgctgccgc tattgccaga atcccgacac gtgggaagtt
    12541 ggacaggggc aggagatgac cgccgaagag ctcctcgcca aagccgaacg ctatcgctcc
    12601 tattggggga aagatggcgg catcaccgta agcggtggag aaccgctgct ccaaatcgac
    12661 ttcctgacgg agcttttcca aaaggcgaag gagcgcggca tacacacctg tatcgacacc
    12721 tgcggacaac cgttcacccg gcgagagcct ttcttcagca aattccagaa gctgatggac
    12781 tatactgact tgctcttgct cgacatcaaa catatcaatt cactggagca tcagaaactc
    12841 acgcgccatc ccaatgagaa tatcttggat tgtgcgcgct atctctccga gattggaaaa
    12901 cccatctggg tgcgtcatgt ccttgtgccg ggtattaccg acaacgacga ttacctcacg
    12961 gagcttcgcc acttcctgcg cccgctccaa aacatccagc gcatcgatgt gttaccctat
    13021 cattcgctgg gacttttcaa atggaagcaa cgcaacatcc cctataccct cgagggcgtg
    13081 ccatcgccca cagcagagcg tatagaaaac gcgcgccgca tcctcacgca ggattgataa
    13141 gaaagtataa gctgttcgcc acattgccga acagcccatt tagctctatc cgcaacaccg
    13201 ttcaaccaag tgttgcggat ttttactgcc tcacccctcc atcttgccgc atcttccgcg
    13261 ttgacagctc ccactaaaaa tgcgaatagc tcttaaaatt tttcattcag tgaagctttt
    13321 cagaaacttc actgaagttt tctctccctt tagtaatgta aaaaaaccgt tgtttatatc
    13381 ctcactggag cttccaaaga tgtccccaaa ctttttatag aggggatctg aaaatataat
    13441 cagctgcatc gtccgtatcc ttattgcctt ctccgctcgc ccttattgca tttggagatg
    13501 caataaggct ctccgcttgc acccttattc tgtccgctca cgcccttatt gcgtttggga
    13561 atcccacaag gttctctgct tacgcgctta ttatacccac tccccctccc aagagtttat
    13621 tttttcgttg tcacgcccat aagcttctgt ctatcagcat cttccatcct gcgtgacaac
    13681 gtgacaacaa aaaaacgagt tttttcttgg tggaggagag acggagaatg ctctctctac
    13741 gctttcagtg agacacttgt tgctacctaa tgaaagccat tatatgtatt ttttgcttta
    13801 ttaaacccat tggcggaatt aatttagcgc atacttaatt ctgccgatag gcttgttatt
    13861 gatgaaattt acatattgta gcacggtaag tgcgctgatt ttgctaatga ttctgtcaaa
    13921 cagaccgttt gttatcttag catagtttct tatgactaaa aactggtctg taagttgtga
    13981 aaacagcgtt tcgattctca ttcttgcctt gacaaatgga atgaatgtag gcttccaatc
    14041 cttctgatta acccgatacg gacattcaag tcttatatgt gccgtttcaa ataaccccaa
    14101 ttcgggataa gcagttcttc tttttcctca aaagaagttt caataaaagc ccaaaaagag
    14161 gattattttt cgtatatttg ttgttgat
//
