LOCUS       NZ_CP043554.1          22435 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP043554.1 Vibrio cholerae strain RFB16 chromosome 1, complete
            sequence.
ACCESSION   NZ_CP043554
VERSION     NZ_CP043554.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:44:55
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 772876
            Orig. end    :: 795311
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22435
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[782876:785311]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12435
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..22435
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..22435
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Fumarate2succinate"
                     /region_number="3"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             573..1013
                     /locus_tag="ctg1_685"
                     /transl_table=11
                     /translation="MQNVTRAFQFKHSLLIIVQVAALSLIWFFSDWLVNQFHLPLPANL
                     TGMLILLLLVMLKVVNVEWFRRGASWLLAEMLLFFVPAVVAVVNYQDLMRQEGIKIAVV
                     LVASTILVIASTAWVVDKMHRVELVLARRKRRQIALARSVEK"
     CDS             1019..1708
                     /locus_tag="ctg1_686"
                     /transl_table=11
                     /translation="MSTSLLSLFCFLLTLLFYYASKFLYRRKRSLLLMPLLLAPLLLVI
                     VVMMFHIPYQAYMADAHWLLWLLGPATVAFAVPVYDNRALLRQHWLSLSVGVLVSVLVA
                     ISSTVLLARWLNLPDLLQRSLAMRSITTPFAVEATKSIGGQSDLTALFVVLTGVIGMAV
                     GEIILTVLSIRSRLGKGASLGASAHGAGTAKAYQIGNSEGVVSSVVMMLAGMVTVVIAP
                     WIGRWFW"
     CDS             complement(1783..2310)
                     /locus_tag="ctg1_687"
                     /transl_table=11
                     /translation="MASVGIFFGSDTGNTEAIAKMIQKQLGKKLVHVQDIAKSSKEDIN
                     NFDLLLLGIPTWYYGEAQCDWDDFFPELEAIDFSTKLVAIFGCGDQEDYAEYFCDAMGT
                     VRDIIQAKGATIVGHWPTEGYEFEASKALVDENHFVGLCIDEDRQPELTEQRVTKWVNQ
                     VYEEMCLAELED"
     CDS             complement(2359..2580)
                     /locus_tag="ctg1_688"
                     /transl_table=11
                     /translation="MLYDYMNMLESVGLDLLFASIFFLIGMAIKDVLKQGNVPPFGRRI
                     VWLVLFLGCAGFVAKGIIQLTWEGSGLG"
     CDS             complement(2676..3449)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_689"
                     /sec_met_domain="Abhydrolase_1 (E-value: 8e-24, bitscore:
                     81.9, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSALLNYKREGSGETVVLIHGLFGSLDNLGLLARDLKNDHQVLSL
                     DLRNHGLSFHSDEHNYALMAQDVNQLLEHLNLTSVVVIGHSMGGKVAMKLADIAAEKVH
                     QLVVLDMSPVAYNQRRHDNVFAGLEAVLAQKPTSRSEVMAILAQHIEQEGVRQFLGKSL
                     MSEQNVMTWRFNVAALKAHYAEILGWDIIAKCRIPTLFIKGADSDYLTTQHQPMVQAQF
                     SQAKAHVIANTGHWLHAEKPAEVLRAIRKFIDVPV"
     CDS             3542..4075
                     /locus_tag="ctg1_690"
                     /transl_table=11
                     /translation="MKTIEVDEDLYRYIASQTLHIGESASDILRRLLNVDGELATAAPA
                     AEPKGIVVSKDAAFDTKIDGVKAMRSLLISDEFAGLKNAIDRFMLILSTLHRIDSASFS
                     EATMVKGRKRVYFADNEQTLLASGQTTKPKAIPNTPFWVITNNNTSRKQQMVEQVMVRM
                     GFPSDIIEKVTHSI"
     CDS             4184..5830
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PGM_PMM_IV"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PGM_PMM_I"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PGM_PMM_III"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PGM_PMM_II"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_691"
                     /sec_met_domain="PGM_PMM_IV (E-value: 3.5e-07, bitscore:
                     27.6, seeds: 63, tool: rule-based-clusters)"
                     /sec_met_domain="PGM_PMM_I (E-value: 3.7e-41, bitscore:
                     137.3, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="PGM_PMM_III (E-value: 3.8e-29, bitscore:
                     98.5, seeds: 437, tool: rule-based-clusters)"
                     /sec_met_domain="PGM_PMM_II (E-value: 7e-18, bitscore:
                     62.4, seeds: 62, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMHPRAGQKARQEDLHNIPALVANYYLLQPEAGNTAHKVEFGTS
                     GHRGTADKTTFNEHHILAIAQAVADVRREHGVTGPIFIGKDTHALSEPAFSSVLEVLIA
                     NGIEVIVQENNGYTPTPGISHAILTYNLKHTDKADGIVITPSHNPPQDGGIKYNPPHGG
                     PAEGELTQAIEDRANAYISQQLAGVKRMPIALAKQSELLKQVDLVKPYVDDLVNVIDMA
                     AIQKAKLKIGVDPLGGSGIDYWRQIGNAYQLDLTLVSEAIDPSFQFMSLDKDGVIRMDC
                     SSPYAMAGLLALKDEYDLAFGNDPDYDRHGIVTPKGLMNPNHFLAVCIDYLYRHRQGWA
                     GHVAVGKTLVSSAMIDKVVADLGRELCEVPVGFKWFVDGLYSGRFGFGGEESAGASFLR
                     QDGTPWSTDKDGIILCLLAAEITAVTGKNPQQYYDELAAKHGDSYYSRIQAVANGPQKN
                     VLKKLSPEMVSAQTLAGDAITARLTHAPGNGAAIGGLKVTTDYGWFAARPSGTEDIYKI
                     YCESFKGAEHLKQIESEAQQIVNQVFKDAGL"
     CDS             complement(5886..6653)
                     /locus_tag="ctg1_692"
                     /transl_table=11
                     /translation="MSKSGGDQMELKHLMDWVIRTPALFQAKAPLVSKAPFSKTTREQW
                     PDYQGNPRLGFLYQHLCAQLFTETPFYNAVSEEIQLINEGKTVGSLDFLAKNRKTEHYE
                     HWEVAVKFYLLHQGCWYGPNAEDRLDIKLDHMLNHQLPLSQHPLFIEQHPLWAGASQHL
                     LMQGRLYTNPFSDEPIPTDCLGYPLNTSQIQGYWCFQREQHLIDEPLYQLEKSDWLTGR
                     KADSELYTEHADGFVHCQSESGKFWFIVPNQWP"
     CDS             6718..7476
                     /locus_tag="ctg1_693"
                     /transl_table=11
                     /translation="MNNLQLEALLNETLSPQLIKDYCPNGLQVEGKAEVKRIVTGVTAS
                     LALIDAAIELKADALLVHHGYFWKNEPEAIRGMKGRRIRTLIQNDLNLYAYHLPLDIHP
                     QLGNNAQLAQRLGICVDGGLEGHPQSVAMFGHFLQPLTGQELAYRIGQVLNRTPLHIAP
                     DQADKLIETVGWCTGGGQDYIELAASRGLDAFISGEISERTTYSAREQSIHYFSAGHHA
                     TERYGIKALGEWLAENHGFDVTFIDIDNPV"
     CDS             complement(7528..8817)
                     /locus_tag="ctg1_694"
                     /transl_table=11
                     /translation="MADKKATLHIEGKAPIELPIMDGSLGPQVIDVRTLGSNGYFTFDP
                     GFLATASCESQITYIDGAKGILLHRGYPIDQLANNADYLEVCYILLYGEAPNRKQYEEF
                     KKIVTRHTMVHEQIASFFHGFRRDAHPMAVMCGVVGALAAFYHDSLDINNDTHREIAAY
                     RLLSKMPTLAAMCYKYSVGQPFIYPRNDLSYAENFLHMMFATPCEEYEVNPIVARAMDK
                     IFTLHADHEQNASTSTVRLAGSSGANPFACIAAGIASLWGPAHGGANEACLRMLEEIGS
                     VDKIPEYVRRAKDKDDPFRLMGFGHRVYKNYDPRATVMREACHEVLKELSIQDPLLDVA
                     MELERIALSDEYFIEKKLYPNVDFYSGIILKAIGIPVSMFTVIFAMSRTIGWIAHWNEM
                     HSDPDNRIGRPRQLYTGQKLRDFTPLHERS"
     CDS             9213..9605
                     /locus_tag="ctg1_695"
                     /transl_table=11
                     /translation="VSKPVKERKSRPVNLDLQTIRFPISAIASILHRVSGVITFVAVGI
                     LLWLLSLSLSSPVGFMEASNIVDSFFVKFVLWGILTALAYHIAGGIRHLLMDLGHFEEL
                     ESGAASAKVAFAATVVLSLLAGVLVW"
     CDS             9599..9943
                     /locus_tag="ctg1_696"
                     /transl_table=11
                     /translation="MVKHVSSFGRNGVHDYLLIRASAIILVLYTIYIVSFCAFTDISYV
                     AWTQFFGSTFTKVFTMLALVSVLIHGWIGLWQVLTDYIKCSKLRAGLQLVVIAVLLGYF
                     FSGLFVLWGA"
     CDS             10001..11710
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 371.8; E-value:
                     1.7e-113)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_697"
                     /sec_met_domain="FAD_binding_2 (E-value: 7e-112, bitscore:
                     371.8, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 3.5e-38,
                     bitscore: 127.7, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAALQISEQGLTCALLSKVFPTRSHTVSAQGGITVALGNSHKDD
                     WQWHMYDTVKGSDYIGDQNAIEYMCKNGPESVIELERMGLPFSRFENGTIYQRPFGGQS
                     KEFGGEQAARTAAAADRTGHALLHTLYQQNVKHKTTIFSEWYALDLVKNQDGAVLGCTA
                     ICMETGEICYFKAKATVLATGGAGRIYASTTNAHINTGDGVGMALRAGVPMQDMEMWQF
                     HPTGIAGAGVLVTEGCRGEGGYLLNKDGERFMERYAPNAKDLAGRDVVARSMMIEIREG
                     RGCDGPWGPHIKLKLDHLGRDVLESRLPGICELSRTFAHVDPVKEPIPVIPTCHYMMGG
                     VPTQVSGQAIKQDSHGKDVEVQGLFACGEIASVSVHGANRLGGNSLLDLVVFGRATGLH
                     LGETLRAQAEARPATASDIEASLARTMRWENSKGGEDPVVIRKDLQRCMQNNFSVFREG
                     KAMAEGLEELKVIRERLKNAHLADKSTEFNTQRIECLELDNLMETAFSTAVAANYRTES
                     RGAHARFDYPERDDENWLCHSIYNPETEQMSKREVNMTPVYRDPFPPKVRTY"
     CDS             11725..12435
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 101.1; E-value: 1.1e-31)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_698"
                     /sec_met_domain="Fer2_3 (E-value: 4.7e-30, bitscore: 101.1,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 3.6e-11, bitscore: 40.7,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.045, bitscore: 11.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLNFSLYRYNPDVDNKPYMKDYILEVEEGSDMMVLDALILLKEQ
                     DPSIAFRRSCREGVCGSDGLNMNGKNGLACITPLSALKGDKIVIRPLPGLPVVRDLIVD
                     MTQFYDNYAKVKPFLIADDALPPSRENLQSPEERAHLDGLYECIMCACCTTSCPSFWWN
                     PDKFIGPAGLLAAYRWLIDSRDTATDERLSNLDDAFSVFRCHGIMNCVSVCPKGLNPTK
                     AIGHIKSMLINRSV"
     CDS             12524..15334
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) E1_dh"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transket_pyr"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_699"
                     /sec_met_domain="E1_dh (E-value: 1e-50, bitscore: 169.7,
                     seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="Transket_pyr (E-value: 4.3e-67, bitscore:
                     222.5, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHNGVMKAWLESSHLAGANATYVEDLYELYLSDPDLVSEEWKRVF
                     DGLPAHPTNVVEQPHSRVRDYFRRLAQETKHYNVQVSDPEVDAKQVKVLQLINAYRFRG
                     HEAAKLDPLGLWNRPEVAELNPSFHNLTQEDMEETFNVGSFAIGKDTMKLKDIYQSLQK
                     IYCGSVGAEYMHITDTEQKRWIQQRLEPVVGTPVFSKEEKRTFLEELTAAEGLERYLGA
                     KFPGAKRFSLEGGDALVPMTKEMIRHAGASGMREVVIGMAHRGRLNMLVNVLGKKPQDL
                     FDEFAGKHGEGWGTGDVKYHQGFSADFATPGGDVHLALAFNPSHLEIVNPVVMGSVRAR
                     QDRLGDEDGSKVLPITIHGDSAIAGQGVVAETFNMSQARGFCVGGTVRIVVNNQVGFTT
                     SNPRDTRSTMYCTDIAKMVQAPIFHVNSDDPEAVAFVTRLALDYRNEFKRDVVIDLVCY
                     RRHGHNEADEPNATQPLMYQKIKKHPTPRKLYADVLTERGECDLETATQLVNEYRDALD
                     HGEVVVKEWRPMAMHSVDWSPYLGHDWHIPWNSEYAMERLQDLGRRVCQYPESHVLHSR
                     VEKIYQDRLSMISGEKMLDWGMAETLAYATLLDDGKRIRISGQDSGRGTFFHRHAVLHN
                     QNDASTYIPLSQIHAGQGPFEVFDSVLSEEAVLAFEYGYATAEPSGLTLWEAQFGDFAN
                     GAQVVIDQFISSGEQKWGRLCGLTMLLPHGYEGQGPEHSSARLERYLQLCAEQNMQVVV
                     PSTPAQVYHMIRRQVVRPMRRPLVVMSPKSLLRHPLCVSSMEDLAHGTFQPAIGEIDAL
                     NPSQVKRVVFCSGKVYYDLLEQRRANEQQDVAIVRIEQLYPFPLEEVQAAIANYTNVVD
                     YVWCQEEPQNQGAWYSSQHNFRAAIPAGADLKYAGRPASASPAVGYMSVHMKQQKALIE
                     DALTLA"
     CDS             15363..16577
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) oxoacid_dh"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_700"
                     /sec_met_domain="Biotin_lipoyl (E-value: 6.4e-20, bitscore:
                     68.0, seeds: 40, tool: rule-based-clusters)"
                     /sec_met_domain="oxoacid_dh (E-value: 3.9e-83, bitscore:
                     275.7, seeds: 75, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIEILVPDLPESVADATVATWHKKPGDMVARDEVIVEIETDKVV
                     LEVPAPDAGVLEAILEQEGATVLSKQLLARLKPGAVAGEPTQDTPDATEPSPDKRHKAS
                     LTEESNDALSPAVRRLLAEHNLEANQVKGSGVGGRITREDIEAHLAANKAKPAAKAEAS
                     VAALAPVVGRSEKRVPMTRLRKRIAERLLEAKNNTAMLTTFNEVNMKPIMDMRKQYQDV
                     FEKRHGIRLGFMSFYVKAVTEALKRYPEVNASIDGDDLVYHNYFDVSIAVSTPRGLVTP
                     VLKNCDTLSLAQIEKGIKELAEKGRDGKLTVDELTGGNFTITNGGVFGSLMSTPIINPP
                     QAAILGMHKIQDRAMVVDGKIEILPMMYLALSYDHRSIDGRESVGFLVTVKELLEDPAR
                     LLLDV"
     CDS             16745..17911
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Ligase_CoA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_701"
                     /sec_met_domain="Ligase_CoA (E-value: 3.1e-25, bitscore:
                     86.0, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLHEYQAKQLFAEFGLPVPEGYACDTPQEAFEAAGRISTAKKVV
                     KCQVHAGGRGKAGGVELHDTKEGVKAFAQKWLGKNLVTYQTDANGQPVSKILVEEASNI
                     ANELYLGAVVDRSTRRIVFMASTEGGVEIEKVAEETPELIHKAAIDPLVGPQAYQGREL
                     AFKLGLQGDQIKQFVKIFMGLGEMFAQYDLALLEINPLVITAEGNLLCLDGKINIDSNA
                     MYRQPKLRQMHDASQEDAREAHAAKWELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGG
                     KPANFLDVGGGATKERVAEAFKIILSDTNVKAVLVNIFGGIVRCDMIAEGIIGAVKEVG
                     VSVPVVVRLEGTNAELGRKVLAESGLDIIAAVSLTDAAQKVVAAAEGK"
     CDS             17911..18783
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Ligase_CoA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CoA_binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_702"
                     /sec_met_domain="Ligase_CoA (E-value: 4.5e-22, bitscore:
                     75.8, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="CoA_binding (E-value: 2.9e-32, bitscore:
                     108.5, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSILINKDTKVICQGFTGGQGTFHSEQAIAYGTQMVGGVSPGKGG
                     TTHLGLPVFNTVREAVEVTGATATVIYVPAPFCKDAILEAIDAGIKLIVTITEGIPTTD
                     MIDVKVKLEQTGVRMIGPNCPGVITPDECKIGIMPGHIHKKGKVGIVSRSGTLTYEAVK
                     QTTDEGFGQSTCVGIGGDPIPGSNFIDILKMFQEDPATEAIVMIGEIGGTAEEEAAAFI
                     KANVTKPVVSYIAGVTAPPGKRMGHAGAIISGGKGTAEEKFAALESAGVKTVKSLADIG
                     KALREVTGW"
     CDS             complement(18890..19672)
                     /locus_tag="ctg1_703"
                     /transl_table=11
                     /translation="MIELLLPSLLAGLGIAIIAGPLGSFVVWRRMAYFGDTLAHASLLG
                     LALGFLLDINLYLALLVCCLGMAAILVAMQKQKLIATDTLLGIMAHSALSLGMIAVSFL
                     DNVRIDLMSYLFGDLLAISPSDLTFIWFGVVTVSLIVYLLWQPLLSTSVNEELAFVEGT
                     NTDLMRLILMLLIGLVIAVGMKFVGALIMGSLLIIPAATARRLSRTPEAMAFWAIGLGV
                     LSVIGGLALSWHFDTPAGPSVVVSAAVLFVLTQFKRVA"
     CDS             complement(19665..20453)
                     /locus_tag="ctg1_704"
                     /transl_table=11
                     /translation="MAILIELQDICVDFEQRRVLDNIRLTLTKGNITTLIGPNGAGKST
                     LVKVILGLQSLSSGKIIRQSGIRIGYVPQKLKLNDTLPLTVNRFLKLAGRFSTQELSEA
                     LRLVGGEHLQSSDMHKLSGGETQRVLLARALLQRPDLLVLDEPAQGVDVQGQIDLYDLI
                     HTLRNRFGCAVLMVSHDLHLVMAKTDEVICLQHHVCCSGSPESIAKHPSYLAMFGHRSR
                     DTLAFYQHHHEHHHHDLSGLPVKGKASACSHHSHGHHKHD"
     CDS             20537..21421
                     /locus_tag="ctg1_705"
                     /transl_table=11
                     /translation="MLSRYFLLTVAALFAQSASAIEVLTSIKPIQMITYELMLGTGTPD
                     VLLPSGASPHDYALRPSDVKRIQQADLVIWFGQDLEPFMSKLLEGRTSALTLSQVPNLA
                     LREYGEEEQHEHDGHHHGHYDPHFWLGIGPVGQVASAITAKLIELDADQQQQYQDNLVR
                     FLANLAEQDNTIGEKLKPVTTVPYYVFHDAYGYFEQHFALNNLGHFTVSPERKPGAKTL
                     IAIKKTLNDQLAKCVFSEPQFEPAIIETVVRGTSAKIGVLDPLGSSIELKAGSYFAFLN
                     SLAESYYACLSQS"
ORIGIN
        1 ggatgctgat taggggaaag catggtcacc gccacatcaa tatcaccgtc taagatcgct
       61 tgttctatct tacgtccgcc atactccacc accgttaatt cgacgttagg gtacgtctga
      121 cgatattgac gaaataaccg tgcgtaaaca tgccccacca tgggcggaat gcctaaacgc
      181 aaatggccgc gctgcagttg gtttaaatcc gtgagttccg cgtccagttg ctgcatttgg
      241 gttaagatct gctgtgctct ttgatagaca atctctccgg cttcagtcag ccagaagcgt
      301 cgtccttcac gatgtagaag gggctgttct aactcctgct ccaaattacg gatcatctta
      361 ctgatggttg gctgagtcac aaacaggcgc tcagaggctt tggtaaaact ctgctggtta
      421 accagttcaa cgaagtagcg cagagcccgg atatccatgt gttacctctt gtatgcctaa
      481 atggcatgaa ttaaataaat ttaagtcatt ttatgctggt aatcacccgg aatacaatgt
      541 gacccagttc ccattttatc taggcaacct taatgcaaaa cgttacgcgt gcttttcagt
      601 ttaagcatag cctactgatt atcgttcaag tggcggcact ttcactgatt tggttttttt
      661 ccgattggtt ggtcaatcag tttcacctgc cgttacccgc caatttaacg ggaatgctga
      721 ttttgttgtt actggttatg ctcaaagtgg taaatgtcga gtggtttcgg cgtggggcga
      781 gctggttgct ggctgaaatg ttgctgtttt ttgttccggc tgtcgtggcg gtggtgaatt
      841 accaagactt aatgcgccaa gaggggatta aaattgctgt ggttttagtg gccagcacca
      901 tcttggtgat cgcatcgacg gcttgggtag tcgataaaat gcatcgagtt gagctggttt
      961 tagcgagacg taaacgtcgc cagatagcgc tggcgcgcag tgtggagaag tagaatatat
     1021 gtcgacttca ttactcagcc ttttctgttt tctgctcacg ttactgtttt actatgcgag
     1081 taaatttctt tatcgacgta aacgcagttt gttgctgatg ccgctgttac tcgcgccatt
     1141 gctgctcgtc atcgtggtga tgatgtttca tatcccttat caagcttaca tggccgatgc
     1201 ccattggcta ttgtggttac tgggcccagc aaccgtcgct tttgccgttc cggtttacga
     1261 taaccgggcg ttattgcgtc agcactggtt atccttatcc gttggtgtct tggtatcggt
     1321 gctggtggct atttcaagta cggtgttgtt ggcgcgttgg ctcaaccttc ctgacttgct
     1381 gcaacgcagc cttgctatgc gttctattac cacccctttt gcggtagaag cgacgaaatc
     1441 gattggtgga caaagtgatc taaccgcgct gtttgtggta ctgacagggg tcattggcat
     1501 ggctgttggt gagataatcc tcaccgtgct ttctattcgc tctcgcttag ggaaaggagc
     1561 aagtttaggg gcttcagctc atggtgctgg cacggctaaa gcctatcaaa tcggtaattc
     1621 agagggtgtg gtgtccagcg tagtgatgat gttggcgggc atggtaactg tggtgatcgc
     1681 tccttggatt ggacgctggt tttggtgata ggcagaaatt gaaactcccc ctaataaaaa
     1741 atcccctgct gggcagggga ttttttattt tgactctgca aattagtctt caagttcagc
     1801 gagacacatc tcttcataaa cttggttaac ccatttggtc acgcgttgct cagttagctc
     1861 tggctggcga tcttcatcga tacacagacc gacgaagtga ttttcatcca caagggcttt
     1921 agaagcttca aattcgtaac cttcggttgg ccagtggccg acaatggttg cgcctttcgc
     1981 ttgaatgatg tcacgtacgg tgcccatcgc atcgcagaag tactctgcgt aatcttcttg
     2041 gtcaccacaa ccaaaaatgg caacaagctt agttgaaaaa tcaatggctt ctagctcagg
     2101 gaaaaagtcg tcccagtcgc actgtgcttc accgtagtac caagtcggga tacccagcaa
     2161 cagcaggtcg aagttattga tgtcttcttt gctgcttttg gcaatatctt gtacgtgaac
     2221 cagtttttta ccgagttgtt tttgaatcat ctttgcaata gcttcggtgt tgccggtgtc
     2281 gctgccaaag aagataccta cacttgccat agaatcatta cctttagaat gttaaagagt
     2341 cgcgaagcct tgcggagctt aacctagtcc actgccttcc caagtcaatt gaattatgcc
     2401 tttggcgaca aagcctgcgc accctaaaaa gagaaccaac cacacaatac gacgcccgaa
     2461 agggggaaca ttaccttgtt tcaacacatc tttaatcgcc atgccaatca agaagaagat
     2521 tgaggcaaac agcagatcga gtcctacaga ctccaacatg ttcatgtagt cgtaaagcat
     2581 gatattcctt tatgccaaat tgcttgcgcg cactatacca ctgttatctg acaaagttaa
     2641 tgcgcgtagt gtttctcaat tcacacttga ttgccttaaa caggcacatc aataaattta
     2701 cggattgcac gtaaaacttc agcgggtttt tccgcgtgca gccagtgtcc cgtgtttgcg
     2761 atcacatgag ctttggcttg gctaaactgg gcttgcacca tgggctgatg ttgtgtggtc
     2821 agataatccg aatctgcccc tttaataaat aaggttggaa tccggcattt ggcgatgata
     2881 tcccagccta aaatctctgc ataatgtgct ttgagtgccg caacattgaa gcgccatgtc
     2941 atcacgttct gttccgacat taaagatttg ccgagaaatt gtctaacgcc ttcttgctca
     3001 atatgttgcg ctaaaattgc catcacttca ctgcgtgagg tgggcttttg cgctaacacc
     3061 gcttcgagtc cagcaaacac attgtcgtga cgccgttggt tatacgcgac aggtgacatg
     3121 tccagcacca ctaattgatg gactttttct gcggcaatat cggctaattt catggccact
     3181 tttccgccca tcgagtgacc gatcaccact accgaagtga ggttgaggtg ttcaagcaac
     3241 tggtttacgt cttgtgccat caacgcgtaa ttgtgctcat cactgtggaa ggatagcccg
     3301 tggttacgca gatccaagct cagtacttgg tgatcgtttt tcagatcgcg cgcaagcaag
     3361 ccaagattat ccaagctacc aaataagcca tggatcaaaa caacggtctc accgctgcct
     3421 tcacgtttgt agttaagaag tgctgacatt ttatcttatt agtgattggt ttaacgtaga
     3481 gtctcagtca agatctcgct ataatccccg aaagtttaaa catagagatt gtgaaaagcg
     3541 aatgaaaaca attgaggttg atgaggatct ataccgttac attgcgagtc agactttgca
     3601 tattggtgaa agtgcctccg atattttgcg tcgtcttctc aatgtagatg gtgaattagc
     3661 cactgctgcg cctgctgctg agccgaaagg gatagtcgta agcaaagatg ccgctttcga
     3721 taccaaaatt gatggtgtta aagcgatgcg ttcactgctg atttccgatg aatttgccgg
     3781 gctaaaaaat gcgatcgatc gcttcatgct gattctgtct actcttcatc gcatcgactc
     3841 tgcgagcttt tctgaagcga ctatggtcaa aggtcgcaag cgcgtttact ttgctgataa
     3901 cgaacagacg ttgcttgcca gcgggcaaac aaccaaacct aaggcgatcc caaatacgcc
     3961 gttttgggtg atcaccaaca acaacactag ccgcaagcaa cagatggttg aacaggtgat
     4021 ggtgcgcatg ggcttcccaa gcgacattat tgagaaagtt acccattcca tttgaatttt
     4081 gctgattaca gcccaaaatt ctgattcaag cctcataatg cgtagtgcta caccgctatt
     4141 atgaggtttt attttatgtg aaatttaaag aaaggatgtc actatggcta tgcaccctcg
     4201 tgctggacaa aaggcgcgac aagaggatct ccataatatc cctgcgctag ttgcaaatta
     4261 ctacctactc cagcctgaag ctggcaatac ggcgcataaa gttgaatttg gtacgtcggg
     4321 acaccgaggt acggccgata aaaccacctt taatgaacat catattcttg cgattgcgca
     4381 agcggtagcg gatgtgcgcc gtgagcatgg tgtgactggc ccaatcttta ttggcaaaga
     4441 tactcatgcg ctgtctgaac ctgcattcag tagtgttctg gaagtgttga ttgccaatgg
     4501 cattgaagtg attgtgcaag aaaacaacgg ctacactccc accccaggta tttcacacgc
     4561 cattttaacg tacaacctga agcatacaga taaagcggac ggtattgtaa ttaccccttc
     4621 gcacaacccg ccacaagatg gtggcatcaa atacaaccca ccacacggtg gtcctgcaga
     4681 aggtgagcta acccaagcga ttgaagatcg tgccaatgct tacatcagtc agcagcttgc
     4741 tggtgtaaaa cgcatgccga ttgcgttggc taaacaatcc gagttgctca agcaagtcga
     4801 tttggttaag ccttacgttg atgatctggt caatgtgatt gatatggcgg cgatccaaaa
     4861 ggccaagctc aaaatagggg tcgatcctct gggcggaagt ggcatagatt actggcgtca
     4921 aattggcaac gcttaccaac tcgatttaac gctggtcagc gaagccattg atccaagctt
     4981 ccaattcatg tcattagata aagatggcgt gatccgtatg gattgctctt ccccatatgc
     5041 catggcgggt ttgctggccc tgaaagatga atacgacttg gcttttggta acgatcctga
     5101 ctacgaccgt cacggcattg tgacccctaa aggcttgatg aatccgaacc acttcctcgc
     5161 ggtgtgcatt gattatctgt accgtcatcg tcaaggttgg gcgggtcatg ttgccgtcgg
     5221 taaaacgctg gtttccagtg cgatgattga taaagtggtt gccgatcttg gccgcgaact
     5281 gtgtgaagtt ccagtgggct tcaaatggtt tgttgatgga ctctactctg gtcgctttgg
     5341 ttttggcggt gaagagagtg cgggggcttc tttcctgcgt caagacggca cgccttggtc
     5401 taccgacaaa gacgggatca ttttgtgctt actggcagcg gaaattaccg ctgtgaccgg
     5461 caaaaatccg caacagtatt atgatgaatt ggcagctaaa cacggtgatt cttattacag
     5521 ccgtattcaa gccgtggcga atggtccaca gaagaatgtg ctaaagaaac tgtctcctga
     5581 aatggtgtcg gctcaaacgc tagcgggaga tgcaattacg gctcgcttga ctcatgctcc
     5641 gggtaatggc gcagccattg gcggcctcaa agtgactacg gattatggtt ggtttgcggc
     5701 tcgtccatct ggcacagaag atatctataa gatttattgt gagagcttca aaggagctga
     5761 gcacttaaaa caaattgaat ctgaagcgca gcagatcgta aaccaagtgt ttaaagacgc
     5821 aggtttatag tgtgatgaaa tgaatcaggg gcgatgagat cgcccctttt ttatgtctct
     5881 taacgctatg gccactggtt tggcacaata aaccagaatt tcccagattc agattggcaa
     5941 tgcacaaacc catctgcgtg ttctgtataa agttcagagt ctgctttccg tcccgtcaac
     6001 caatctgact tttcaagctg atataaaggt tcatcgatta agtgctgctc acgctggaaa
     6061 caccaatacc cttgaatctg gctagtattg agcgggtagc caaggcaatc ggtcgggatt
     6121 ggctcatcag aaaatggatt ggtataaaga cgaccctgca ttaataaatg ttgtgatgca
     6181 ccagcccaga gtggatgttg ttcaataaaa agcggatgtt gtgatagtgg cagttggtgg
     6241 ttgagcatat ggtcaagttt gatatccaaa cgatcttcgg cattggggcc gtaccaacat
     6301 ccttggtgga gcagataaaa tttgactgcc acttcccaat gttcataatg ttcagtttta
     6361 cggtttttag ctaaaaaatc caatgaaccg acggtttttc cttcattaat gagctgaatt
     6421 tcttctgaaa ccgcattgta aaatggcgtt tcggtgaata attgagcgca aagatgttga
     6481 tagagaaagc ctaatcgtgg attgccctga tagtctggcc actgttctcg tgttgttttg
     6541 ctaaatggcg ctttgctgac caaaggcgct ttggcttgaa atagggcagg ggtgcgaatc
     6601 acccaatcca ttaagtgttt taactccatc tgatcaccac cactttttga catatttcga
     6661 cattctagcc tgaaattgtt ataaccacgc cacctctgtt gctcaatgga ttacaagatg
     6721 aacaatttac agctagaagc gttgctaaat gagacattgt ccccacagtt aattaaagat
     6781 tattgtccta atggtttaca agtcgaaggt aaagcggaag tcaaacgaat tgtcaccggt
     6841 gtgaccgcga gtttagcgct gattgacgct gcgattgagc tcaaagccga tgcattattg
     6901 gtgcatcacg gttatttttg gaaaaatgaa cctgaggcca ttcgaggtat gaaaggtcgc
     6961 cggatacgta cgcttatcca aaatgatctt aatctgtatg cctaccatct gcctttggat
     7021 attcatccac agttgggcaa caatgctcag cttgcgcagc gactcgggat ttgcgttgat
     7081 ggtggattgg aagggcatcc tcaatcagtt gcaatgtttg ggcacttttt acaaccgtta
     7141 accgggcaag aattagctta tcggattggc caagtcctga atcgtacacc tttgcatatt
     7201 gctcccgatc aagccgataa gttgattgaa actgtcggtt ggtgtacggg tggtgggcaa
     7261 gactatattg aactcgcggc tagccggggt ttagatgcct ttatttctgg agaaatctcg
     7321 gagcgtacaa cctattcggc acgtgaacag tcgatccatt acttttccgc aggtcaccat
     7381 gctaccgagc gctacggaat taaagcacta ggggaatggc tcgcggaaaa tcacggcttt
     7441 gatgtgacct tcattgatat tgataatcca gtttagaaca ataaaaaaga gcgagaaaat
     7501 ctcgctcttt tgcttttgaa tcaatgatta actgcgttca tgcaaggggg tgaaatcgcg
     7561 cagtttttga cctgtgtaca actgacgtgg acgaccgata cggttgtccg gatcgctgtg
     7621 catttcattc cagtgagcaa tccaaccgat agtacgagac atcgcaaaga tcaccgtgaa
     7681 catagacaca ggaataccaa tggctttgag aatgatgcct gagtagaaat cgacgttagg
     7741 atagagtttc ttctcaataa agtactcatc agacagcgca atacgctcaa gttccatcgc
     7801 gacgtcgagc agtggatctt gaatgcttag ctctttcagc acttcatgac acgcttcacg
     7861 cattacagtg gcacgtggat cgtagttttt gtacactcgg tgaccaaagc ccattagacg
     7921 gaatgggtca tctttgtctt ttgcacgtct tacgtattca ggaatcttat caacagagcc
     7981 gatctcttca agcatacgta gacaagcttc gtttgcgcca ccatgtgcag ggccccaaag
     8041 agaagcgata cctgctgcga tacacgcaaa tgggttagca cccgatgaac ctgccagacg
     8101 tacagtcgat gtcgatgcgt tttgttcatg atccgcatgt agagtgaaaa tcttgtccat
     8161 ggcacgagcc acgataggat tcacttcata ctcctcacaa ggtgtggcaa acatcatgtg
     8221 caggaagttt tctgcatagc tcaaatcgtt acgtgggtag ataaacggtt gaccaactga
     8281 gtatttgtaa cacatcgcag ccaaggtcgg cattttggaa agcagacgat aagccgcaat
     8341 ttctcggtgg gtgtcgttat tgatatcgag tgaatcatga tagaaagcag ctaacgcacc
     8401 caccacacca cacatcacag ccatcgggtg agcatcacgg cggaaaccgt ggaaaaagct
     8461 cgcgatctgt tcatgaacca tagtgtgacg agtaacgatt ttcttgaact cttcatattg
     8521 cttacgatta ggggcttcac cgtaaagaag gatgtaacac acttccaagt aatcagcgtt
     8581 attggctaac tgatcgatag ggtagccgcg gtgcaacaga atgcccttag cgccatcgat
     8641 ataagtaatt tgagattcac aggatgcagt ggcaagaaaa cccgggtcaa aagtaaagta
     8701 accgtttgag cctaaagtac gaacgtcaat cacttgtgga ccaagcgatc catccataat
     8761 tggcaattcg attggcgctt taccttcgat gtgaagggtc gctttcttat ccgccataac
     8821 catctccttt gtttattatt taatccgtcc aggatgtttt gtgtgtgatt cttgtacgtc
     8881 cgatcttaat caaagtcaat tattctcctc tgatgtgtgc actcactttg attttttata
     8941 cgtataaagt taaaaatctg ttctgtgtag caaaaattgt tacagcaatt gtattagaat
     9001 gttgcagtcc gtatagtgac acagaaaatt ctgtgagaga ccttataaat tcaaggctag
     9061 aaagaaattt aacttataga ttttagactt gggtgtaaca tttaaactac aattaagtcg
     9121 ccgatttggc ggttgaaatg ttgaataaat gttaaattat gcgcattttc gaccagaatt
     9181 catccataac tataaatgct caatggagct gagtgagcaa gcccgtgaaa gaaagaaagt
     9241 caagacctgt taatttagat ttgcagacca ttcgctttcc gatctcagca atcgcatcca
     9301 tcctccaccg tgtgtcgggg gtgattacgt ttgttgcggt tgggattttg ctttggttgt
     9361 tatccctctc tctctcctca cctgtcggat ttatggaagc gagcaacatt gttgacagct
     9421 ttttcgtgaa attcgtgttg tggggaattc taactgctct ggcctaccac attgctggtg
     9481 ggattcgtca tttattgatg gatcttggtc actttgaaga gctggaatcc ggtgccgcga
     9541 gcgccaaagt agcttttgcc gctacggttg tattgtctct actggcgggg gttctggtat
     9601 ggtaaagcat gtctcttcat ttggtcgtaa tggtgttcac gattacttat tgatccgcgc
     9661 ttcagcgatc atcttagttt tgtacactat ttatatcgtg agtttttgcg cgttcacgga
     9721 catctcttat gtcgcgtgga ctcaattctt tggtagtacg ttcaccaaag tcttcacaat
     9781 gttggcatta gtttcagtat tgattcatgg ctggattggt ctatggcaag tactgacgga
     9841 ttacattaag tgctccaaat tgcgagcggg gctgcaactt gtggtcatcg ccgttctact
     9901 aggatacttc ttctctggcc tatttgtatt gtggggtgcc taagtgacta ttccagttcg
     9961 ttcttttgac gccgtagtaa tcggcgcagg tggtgcaggc atgcgtgctg cactacaaat
    10021 ttctgagcaa ggcctaactt gcgcactgct ttcaaaagtg tttccaactc gttctcatac
    10081 ggtatccgct caaggcggca ttaccgtggc tttgggtaac tcacataaag atgattggca
    10141 gtggcatatg tatgacacgg taaaaggttc cgactatatc ggcgaccaaa atgccatcga
    10201 atacatgtgt aaaaacggtc cggaatccgt gattgaactt gagcgcatgg ggttgccttt
    10261 ttctcgtttt gagaacggca cgatttatca acgtcctttt ggcggtcagt caaaagagtt
    10321 cggtggtgaa caagctgctc gtacggcagc agcagcagac cgtactggtc atgctctact
    10381 acacacgctt taccaacaaa acgttaaaca taaaaccacc attttctcgg aatggtatgc
    10441 gctggatctg gtgaaaaacc aagatggtgc tgtgctcggt tgtactgcaa tctgtatgga
    10501 aacaggcgaa atttgctact tcaaagccaa agcaacagtg cttgcgacag gcggtgcagg
    10561 tcgtatttac gcttcaacca ccaatgcaca cattaacacg ggcgatggtg tcggtatggc
    10621 tttgcgtgct ggcgtaccaa tgcaagatat ggaaatgtgg caattccacc caacgggtat
    10681 cgcgggtgct ggcgttctgg ttacagaagg ctgtcgtggc gaaggcggct atctgctgaa
    10741 taaagatggt gagcgtttca tggaacgtta tgcacctaac gctaaagatc tagcaggtcg
    10801 tgacgtggtt gcacgttcaa tgatgatcga aatccgtgaa ggtcgtggtt gtgacggtcc
    10861 ttggggtcca cacatcaaac tgaaactgga tcacttaggt cgtgatgtat tggaatctcg
    10921 cctaccgggt atctgtgaac tatcacgtac ctttgctcac gtggacccag tgaaagaacc
    10981 tattcctgtt atcccaacct gtcactacat gatgggtggt gtaccaacgc aagtgtctgg
    11041 tcaagcgatc aaacaagaca gccatggtaa agatgtcgaa gtccaaggct tgtttgcttg
    11101 tggtgaaatc gcttctgtat cggtacatgg tgccaaccgt ttaggtggca actcactgct
    11161 tgatctggtg gtatttggcc gcgcaacggg tctacatctt ggtgaaactc tgcgtgctca
    11221 agctgaggct cgccctgcga ctgcatcgga tatcgaagct tctctggctc gtactatgcg
    11281 ctgggaaaac agcaaaggtg gcgaagaccc agttgttatc cgtaaagatc tgcagcgctg
    11341 catgcaaaac aacttctcgg tattccgtga aggtaaggcg atggctgagg ggctggaaga
    11401 gctcaaagtc attcgcgaac gtttgaaaaa tgctcatctg gcggacaaat caaccgaatt
    11461 taacactcaa cgtattgagt gtttagagtt ggacaacctg atggaaacag cattttcgac
    11521 cgcagtagcg gcaaactacc gtactgaaag ccgtggtgca catgcgcgtt ttgactatcc
    11581 agagcgtgat gatgagaact ggttgtgcca ctcaatctac aatccggaaa cggaacagat
    11641 gagtaagcgt gaggtcaata tgactccggt ttaccgtgac ccgttcccgc ctaaagtgcg
    11701 tacatattaa gggaggtact caatatgaaa ctcaacttct ctttatatcg ctataatccg
    11761 gatgtcgata acaaacccta catgaaagac tacattcttg aggtagagga agggtctgac
    11821 atgatggtgt tggatgcttt gattctgctt aaagagcaag atccaagtat tgctttccgc
    11881 cgctcatgcc gtgaaggggt ttgtggctcg gacggtctga atatgaatgg taagaatggc
    11941 ttagcatgta tcacaccttt gtctgcgtta aaaggtgaca aaattgtgat tcgtccactg
    12001 ccaggattac ctgtggttcg tgacttgatt gtcgacatga ctcagtttta cgataactat
    12061 gcgaaagtta agcctttctt gattgcagat gatgcattac ccccttcaag agagaacttg
    12121 caatcccctg aagaacgggc gcatttggat ggtctgtacg agtgtattat gtgcgcttgc
    12181 tgtaccactt cctgcccttc attctggtgg aatccggata aatttatcgg acctgcaggt
    12241 ttgttggctg cttatcgttg gttgattgat agccgtgata ccgcgacaga tgaacgctta
    12301 tcgaatcttg atgatgcgtt tagcgttttt cgttgccacg gcatcatgaa ctgtgtcagt
    12361 gtttgtccga aaggattaaa cccaacgaaa gccattggac atattaagtc catgttgatc
    12421 aatcgttcag tttaaattga aaattgcagg ccttcgagcc tgccttttat agctcggcga
    12481 taagaccgca gcaaacgtga aaactactgg ttaagggaaa aaaatgcaca acggcgtgat
    12541 gaaggcatgg ctcgagtctt cacacttggc tggcgccaat gcaacttacg tagaagatct
    12601 ctacgaactg tatctaagtg atcccgatct ggtaagtgag gagtggaaac gtgtttttga
    12661 tgggttgcct gcgcacccaa cgaatgtggt tgaacaaccg cactcacgcg tccgtgacta
    12721 cttccgacga ctcgctcaag agactaagca ttacaatgtc caagttagtg atcctgaagt
    12781 cgatgcaaaa caagtaaaag tactgcagct aattaacgca taccgtttcc gcggtcatga
    12841 agctgccaag cttgaccctc tcggtttatg gaaccgccct gaagtggcgg agctgaatcc
    12901 ctcattccat aatttgaccc aagaagatat ggaagagacc ttcaacgtgg gctcctttgc
    12961 gattggcaaa gacacgatga agctgaaaga tatctatcaa tccctacaaa aaatctactg
    13021 tggctctgtc ggtgcagaat acatgcacat caccgacact gagcagaagc gttggattca
    13081 acagcgcctc gaaccagttg tgggtacccc tgtattcagt aaagaagaaa agcgtacttt
    13141 ccttgaagag ctgactgccg ctgaaggttt agagcgttat cttggtgcga aattccctgg
    13201 tgctaaacgt ttctctctcg aaggggggga tgccttagtt ccgatgacca aagagatgat
    13261 ccgtcacgcg ggtgctagtg gcatgcgtga agtggtgatt gggatggcgc accgcggtcg
    13321 cttgaacatg ctggtcaacg ttctgggtaa aaaaccacaa gatctgtttg atgagtttgc
    13381 cggtaaacat ggcgaaggct ggggcacagg tgatgtgaaa tatcaccaag gtttctccgc
    13441 tgactttgcg acaccgggcg gtgatgttca cttagcactg gctttcaacc catcgcatct
    13501 tgagattgtg aaccctgttg tgatgggttc agtgcgcgcg cgtcaagacc gcctaggtga
    13561 tgaagatggc agtaaagtgc tacctatcac tatccatggt gactctgcga ttgccggaca
    13621 aggtgtggtg gctgaaacct tcaacatgtc tcaagcgcgt ggtttctgcg tcggtggtac
    13681 agtacgtatc gtggtcaata accaagtggg cttcacgaca tcaaacccac gcgatactcg
    13741 ctcaaccatg tactgtaccg atattgccaa gatggttcag gcaccgattt tccacgtgaa
    13801 ttcagacgat cctgaagctg tagcttttgt cactcgtcta gcgcttgatt accgtaatga
    13861 attcaagcgc gatgtggtga ttgatctggt gtgttatcgc cgtcatggtc ataacgaagc
    13921 ggatgagcca aacgcaactc agccgttgat gtaccaaaaa atcaagaagc atccaacacc
    13981 tcgcaagctg tatgcagatg tgttaactga gcgtggtgag tgcgatctcg aaaccgcgac
    14041 tcaactggtg aatgaatatc gcgatgccct agatcacggt gaagtggtgg tcaaagaatg
    14101 gcgtccaatg gcgatgcact ctgtggactg gtcaccgtat ttaggtcacg actggcatat
    14161 tccttggaat agcgaatatg cgatggagcg attgcaagat cttggtcgtc gtgtttgcca
    14221 atatccggaa agccatgtgt tgcatagccg tgtagaaaaa atctaccaag atcgtctctc
    14281 tatgatctct ggcgagaaga tgctggattg gggtatggct gaaacgcttg cgtatgccac
    14341 attgcttgat gacggtaagc gcatccgtat ctcaggtcag gactctggtc gtggaacctt
    14401 cttccaccgt cacgctgttc tgcataacca aaacgatgcg agtacttata ttccactctc
    14461 acagatccat gctggccaag gcccgtttga agtctttgac tcagtattgt cagaagaggc
    14521 ggtattggca ttcgaatacg gctatgcgac tgcggagcct agcggtttga cgttgtggga
    14581 agcacagttt ggtgattttg ctaacggtgc gcaggtggtt attgaccagt ttatctcctc
    14641 tggtgaacag aagtgggggc gtctatgtgg cctgactatg ctgctgccac acggttatga
    14701 aggccaaggt cctgagcact cctctgcacg tttagagcgt tacttgcagc tgtgtgctga
    14761 gcaaaacatg caggtggttg ttccgtctac ccctgctcag gtttaccaca tgattcgtcg
    14821 tcaagtggtt cgcccaatgc gccgccctct ggtggtgatg tctcctaaat cgctgctgcg
    14881 tcatccactg tgtgtctcca gtatggaaga tcttgcccac ggtactttcc agccggcgat
    14941 tggtgaaatt gatgcgctga atccgtcgca agtaaaacgc gttgtgttct gttctggtaa
    15001 ggtttattac gatctccttg aacagcgccg agccaatgaa cagcaagacg tggcgattgt
    15061 tcgtatcgaa cagttgtacc cattccctct ggaagaagta caagcggcca ttgcaaatta
    15121 caccaatgtg gtggattacg tctggtgtca ggaagaaccg caaaaccaag gtgcttggta
    15181 tagtagccaa cataacttcc gcgctgcgat tccagcgggt gctgatctga aatacgcagg
    15241 tcgtcccgct tcggcatctc ctgcggtcgg ctatatgtcg gtgcacatga aacaacaaaa
    15301 agcgttgatt gaagacgctc tgaccctagc gtaagaacga gaagtataag gaagatacca
    15361 ttatgaccat tgaaattctg gttccagatt tgcctgaatc agttgcggat gccacggttg
    15421 cgacgtggca taaaaagccg ggtgacatgg ttgctcgcga tgaagtgatc gttgaaattg
    15481 aaactgacaa agtagtgctg gaggttccag cacccgatgc aggtgttctg gaagctattt
    15541 tggaacaaga aggtgcgaca gtgctttcta aacaactgct ggcacgtttg aagccaggcg
    15601 ctgtagcggg tgaaccaacc caagacactc cagatgctac tgagccatca ccagataaac
    15661 gccataaagc atcactaact gaagaaagca atgatgcgct aagccctgcg gttcgtcgcc
    15721 tgcttgctga acataacttg gaagcaaacc aagttaaagg ttctggtgtg ggtggtcgta
    15781 ttacccgcga agacatcgaa gctcacttag ccgcgaacaa agccaaacca gctgcgaaag
    15841 ctgaagcctc tgtcgcagca ctggctcctg tcgtcggccg cagtgaaaag cgcgtgccaa
    15901 tgacacgtct gcgtaagcgt atcgctgagc gtctgttgga agcgaaaaat aacacggcta
    15961 tgctgacgac atttaatgaa gtgaacatga aacctatcat ggacatgcgt aagcaatacc
    16021 aagatgtgtt cgaaaaacgt catggcatcc gtctgggctt tatgtcgttc tacgtgaaag
    16081 ccgtcactga agcgctgaag cgttacccag aagtgaacgc gtctatcgat ggtgatgatc
    16141 tggtttacca caactacttt gatgtgagca ttgccgtatc aaccccacgt ggtctggtta
    16201 ctccagtact gaaaaactgc gataccttga gtttggcgca aattgaaaaa ggcatcaaag
    16261 agctagcaga aaaaggtcgt gacggtaaat tgaccgtaga cgaactgact ggcggtaact
    16321 ttaccatcac caacggtggt gtgtttggtt cactgatgtc aacgcctatc attaacccgc
    16381 cacaagcggc gattctgggt atgcataaga tccaagaccg cgccatggtg gtggatggca
    16441 agattgaaat cctgccaatg atgtatctag cgctgtctta tgaccaccgt tcaatcgatg
    16501 gtcgtgagtc ggttggtttc ctagtgaccg ttaaagagtt gctagaagat ccagcccgtc
    16561 tgctgctcga tgtttaaact gtctattgct cagatttctg agtaatggag aaaagggtcg
    16621 gacatgctca acgtccgacc tggctttggc caaagattgg ctactcgctc aagagtgacc
    16681 ctacaaacgt aaagttcagc tcaatggact ctatggaaga acaataaaca aatggaacaa
    16741 cacaatgaat ttgcatgaat atcaagctaa acagctgttt gcagaattcg gtttgcctgt
    16801 accggaaggt tatgcttgtg atacgccaca agaagcgttt gaagctgcag gacgcatcag
    16861 cacagccaag aaagtcgtaa aatgccaagt tcacgccggt ggacgtggta aagcaggtgg
    16921 cgttgaactg catgacacta aagaaggcgt aaaagcgttt gcacaaaaat ggctaggtaa
    16981 gaacctagta acttatcaaa cggatgcaaa tggccaaccg gtttcaaaaa ttttggttga
    17041 agaagcatca aatatcgcta atgagcttta tcttggtgcg gtagttgacc gctctacacg
    17101 tcgtatcgtt ttcatggcat cgactgaagg tggcgtggaa attgagaaag tggcagaaga
    17161 aactccagaa ctgatccaca aagcggcaat tgatccactg gttggcccac aagcctacca
    17221 aggtcgtgaa ttggcgttca agctaggcct gcaaggtgat caaatcaaac agttcgtgaa
    17281 aatcttcatg ggcttgggtg aaatgtttgc tcaatatgat ctcgcactgc tggaaatcaa
    17341 cccgctggtg attactgcag aaggtaactt gctgtgcctt gatggcaaaa tcaacatcga
    17401 ctccaatgcg atgtaccgtc aacccaaact gcgtcaaatg cacgatgctt ctcaagaaga
    17461 tgcgcgcgaa gcacacgcag cgaaatggga gcttaactac gttgcgctgg atggtaacgt
    17521 aggctgtatg gttaacggtg ctggcctagc aatgggaacc atggacattg ttaacttgca
    17581 cggcggaaaa ccagcaaact tccttgacgt aggtggtggt gcgaccaaag agcgtgttgc
    17641 agaagccttc aaaatcatct tgtctgatac caatgtaaaa gccgtactgg tgaacatctt
    17701 tggtggcatt gtgcgctgcg acatgattgc agaaggcatt atcggtgcag tgaaggaagt
    17761 tggtgtaagc gttccagtgg ttgtgcgtct tgaaggtaca aacgcagaac ttggacgcaa
    17821 agtgctggca gaatcaggtc tagatattat tgcagctgta tctttgacag acgcagctca
    17881 aaaagtagtt gccgcggcgg agggcaaata atgtcgattc ttatcaataa agacactaaa
    17941 gtcatttgtc agggtttcac cggtggtcaa ggtactttcc actctgaaca ggcgattgct
    18001 tatggcacac aaatggttgg tggtgtatcg ccaggtaaag gcggtaccac gcatctaggt
    18061 ttgcctgtat ttaataccgt tcgtgaagcc gttgaagtga ctggcgcaac cgcaactgtt
    18121 atctacgtac cagcaccatt ttgtaaagat gcgattctgg aagcgatcga tgccggcatc
    18181 aagcttattg tgaccatcac tgaaggcatt cctaccactg acatgattga tgtcaaagtg
    18241 aaactggaac agactggcgt tcgtatgatt ggtcctaact gcccaggtgt gattacaccg
    18301 gatgagtgta agattggcat catgccagga cacattcata agaaaggtaa agtgggtatc
    18361 gtttctcgct cgggtacttt gacttatgaa gcggttaaac aaaccacaga cgaaggtttc
    18421 ggccagtcaa cctgtgtggg catcggtggc gatccaattc cggggtcaaa cttcatcgac
    18481 atcctgaaga tgttccaaga agatccagcg acagaagcga ttgtgatgat cggtgaaatc
    18541 ggcggtactg cagaagaaga agcagctgct ttcatcaaag ctaacgtcac aaaacctgtc
    18601 gtttcttata tcgcaggtgt aacggctcct ccgggcaaac gcatggggca tgctggtgcg
    18661 atcatctctg gtggtaaagg taccgcggaa gagaaatttg cagcacttga gtctgcgggc
    18721 gtgaagacag taaaaagtct tgccgatatt ggcaaagcgc tgcgtgaagt gactggttgg
    18781 taatctaccg cgattactta ttcagataat aagaaacccc gaacacagct tcggggtttc
    18841 tttttactaa atgccatttc tttttactaa aagctaatgt gatacagcgt taagcgaccc
    18901 gtttaaactg ggtgagtaca aacaataccg cagcagaaac caccaccgac ggacctgcag
    18961 gtgtgtcaaa gtgccaagat agcgccaacc caccgatcac acttaataca cccagtccaa
    19021 ttgcccaaaa cgccatggct tctggggtgc gtgaaagacg gcgagcagta gccgcgggga
    19081 tgattaacag cgagcccata atcaaagccc cgacaaattt catcccgacg gcaatcacca
    19141 aaccgataag tagcatcaag attaaacgca tcaggtcagt gttggttcct tcaacaaagg
    19201 ccaactcttc attcacgcta gtcgagagaa ggggttgcca gaggagatag acaatcaaac
    19261 tgacagtgac gacaccgaac cagataaagg taagatcgga tgggctaatc gcgagcaaat
    19321 caccaaacag atagctcatc aaatcgatgc ggacattatc aagaaagctc accgcaatca
    19381 taccgagcga tagcgcactg tgcgccataa tcccaagtag ggtatcggtc gcgatgagtt
    19441 tttgcttttg catcgccact aaaatggccg ccatccccaa acagcagacc aatagtgcca
    19501 gatacagatt gatgtcgagt aaaaaaccga gcgccagacc cagtagtgag gcgtgagcaa
    19561 gggtatcacc aaaataagcc attctgcgcc aaaccacgaa agatccgaga gggccagcaa
    19621 taatggcaat tccgaggcca gcaagaagag aaggtagaag aagttcaatc atgtttgtgg
    19681 tgaccatgtg aatgatgtga gcaagcactc gctttccctt tgaccggtaa gccagataaa
    19741 tcgtggtggt ggtgctcgtg gtggtgttga taaaaagcca gcgtgtctcg gcttcgatgg
    19801 ccaaacatcg ctaaataact cgggtgtttg gcgatgctct ccggcgagcc agagcaacag
    19861 acatggtgtt gtaagcagat cacttcgtcg gttttggcca tcaccaaatg taaatcgtga
    19921 gaaaccatca acacagcgca gccaaagcgg ttacgcaagg tgtggatcag gtcgtataag
    19981 tcaatttgtc cttgtacatc aaccccttga gcaggctcgt cgagcacaag caagtcgggt
    20041 ctttgtaata aagctctggc gagcaataca cgctgtgttt caccgccgga gagtttatgc
    20101 atatcactac tttgaagatg ctcacctccc actaggcgta aggcttccga tagctcttga
    20161 gtactaaaac ggccagccag ttttaaaaag cggttcaccg tcagcggtaa tgtgtcattg
    20221 agtttgagtt tttgcggaac atagccgata cgaattcccg attggcgaat gatttttcct
    20281 gaactcaatg attgtaatcc taaaatgact ttcactaagg ttgattttcc tgcaccgttg
    20341 gggccgataa gcgttgtaat attgcctttg gtgagagtta accggatatt gtcaagcaca
    20401 cgtctttgtt caaagtcgac gcatatgtct tgcaattcaa tcagaatagc catggaatag
    20461 aactcatttg caaaatggtt atgttataaa gtaacattca tgcccaataa aagccactaa
    20521 ctggagtttg gcgaccatgt tatcgagata ttttttactt actgtcgcag cactgtttgc
    20581 tcaatcagcc agcgcaatcg aagttctgac cagcatcaag ccgatacaga tgatcactta
    20641 cgagttgatg ctggggacgg ggactcccga tgtactttta ccttctggag catcgccgca
    20701 cgattatgcg ctacgccctt cagatgtaaa gcggattcaa caagcagatt tggttatttg
    20761 gtttggtcag gatcttgaac ccttcatgag taaactgttg gaaggccgta cgtcagcact
    20821 aacattaagc caagttccta atttagcact gcgagaatat ggcgaggagg agcagcatga
    20881 gcatgatggg catcatcacg ggcattatga tcctcatttc tggttaggga ttgggcctgt
    20941 aggacaagtt gcaagtgcaa ttacggcaaa actgattgag ctcgatgcgg atcagcagca
    21001 gcagtatcaa gataatcttg ttcgcttttt agcgaacctt gcagagcaag acaacacgat
    21061 aggtgaaaag ctcaaacctg tcacgaccgt accttattac gtttttcatg atgcttatgg
    21121 ttatttcgaa cagcactttg cattaaataa tctaggccac ttcacggtga gtcctgagcg
    21181 aaagccagga gctaagacac tgatcgcgat taaaaagacg ctgaatgatc aactcgccaa
    21241 gtgtgtattt tcagaaccgc aatttgagcc agcgattatc gaaaccgttg ttagaggcac
    21301 gtcggcgaaa attggtgtgc tcgatccact cggcagctca attgaactca aagcgggtag
    21361 ctatttcgcc ttcctaaata gtttggcgga gagttactac gcgtgtttgt ctcaatctta
    21421 agtcgaccaa tgtctctcac attgttctaa atgcggctta agccgcattt ttttgtatcc
    21481 aaaacctaaa aaagtggtct ttctaaacct ttcaaactgc atacccgcta ggtattcgtt
    21541 agaatgcatg agaatttgtg ctcctctagg ataccgaaac caataaagta cgaattcttg
    21601 aattgtcgct gacaggggaa ctcgtgtttc gcacattgtt gtatggctgc ttgctcaata
    21661 tcctgatccc atccttggta ttggcattag ataaatctat gtctattttc tatcctttgc
    21721 ccattcaaga gcaggggaaa gttattgttg cgcaaaatct ctacctcggt agtgatgggg
    21781 ggatttgggt acatgatgtt catggcaaag tgatgtactt tgatggacaa aacgtcttgc
    21841 ctcgtcgtgg ttctgttctg ccgcagttgt ccagtcatat tgtttatgcg aacagtgcat
    21901 tttgggcttt tgagcaacac gagttgttca gaacctatcc cgggggagaa agagagctga
    21961 tgttgagctt aactccggga acgcagatta ttcagatggg ggcctcaaat ggcatgatct
    22021 ggatggttga tggggaaaac ttctatagtt atgagatccg aagtggccgc gtcgaatccc
    22081 tctcgttaca tgaactttat cagctcaata gtgccagcaa ggtcgtgatt aacgatgcgc
    22141 agtttttagt ctcgaaatgg gctttagcga ctaatgttgg ggtgtattta tctgatgaac
    22201 aaggttttgc ccatgtaaaa aattctggca agcactttat ccaaaagctc tatttttccc
    22261 ataagcggcg agagctgtta gttgggtcta aacgtggcgc gttagtcatt gatattgaaa
    22321 ataaacgtcc accactggat agaattggtt cctcccatgt cctgtctatt gcggaaaccg
    22381 agaaagagta ctggatcggt acagaagatg ggctctttgt ttactctttt atcac
//
