LOCUS       NZ_CP043554.1          20861 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP043554.1 Vibrio cholerae strain RFB16 chromosome 1, complete
            sequence.
ACCESSION   NZ_CP043554
VERSION     NZ_CP043554.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:44:55
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 198157
            Orig. end    :: 219018
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..774)
                     /locus_tag="ctg1_165"
                     /transl_table=11
                     /translation="MRRPVVMGNWKLNGSKAMVTDLLNGLNAELEGVAGVDVVVAPPAM
                     YLDLAERLIKEGGNKLILGAQNTDTHNSGAYTGDMSPAMLKDFGASHIIIGHSERRDYH
                     KESDEFVAKKFAFLKENGLTPVFCIGETEAQNEAGETEAVCARQINAVIDAYGVEALNG
                     AIIAYEPIWAIGTGKAATADDAQRIHASIRALIAAKDAAVAEQVIIQYGGSVKPENAAS
                     YFAQPDIDGALVGGASLDAKGFAAIAKAAAEAKKA"
     protocluster    1..20861
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[206868:209435]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      8712..11278
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..20861
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..20861
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             1018..1368
                     /locus_tag="ctg1_166"
                     /transl_table=11
                     /translation="MPNLVMEYSNSVDERINVQGLLEDLHRAAIDSGLFEISSVKSRAL
                     RCHHWLIGDEGDSVDFIHLSFELLAGRSPEQKRELSRKLMEILAAKASHVRSLTINIRD
                     MDTDCFQKVINR"
     CDS             1388..1828
                     /locus_tag="ctg1_167"
                     /transl_table=11
                     /translation="MSLQTLLFSFQGRIGRQAFWLWNICYYAMIAGFAMGSNLLFPDVA
                     HLILPVFLLVVLVPDLAITAKRWHDRDKSSWWLLLNVPLVIGRMTIPAGELAVNTQPGM
                     LETLISFVALLCGAWILVECGFLSGTDGSNRFGPDPKWIKKS"
     CDS             complement(1957..2316)
                     /locus_tag="ctg1_168"
                     /transl_table=11
                     /translation="MTPPHSPEPCNQVLPPFDELVALAKHHPDAFDQFKKEMCEEMILS
                     ASHAMQQRLWAQQSHIDRVVGQCKNPVHANVTLMRELSQQMVRFRNALEGDLQQETVAD
                     VVPFRPRMVQDDGWR"
     CDS             complement(2455..3072)
                     /locus_tag="ctg1_169"
                     /transl_table=11
                     /translation="MKTVDRILHTIKREGTVTAKQLAEDLGITTMGARQHLQSLEEEGV
                     LAFHDVKVKVGRPTRHWSLTAKGHNQFADRHGELTIQVIDAVEHIFGKEGLAKVAAERE
                     AQTFAAYHNALVGCHSLQEKLEALVTLREQEGYMAELESTADGFILIENHCPICKAATR
                     CPSLCQSELNVFRRLLGEECHIERREHIVAGERRCTYFIAAR"
     CDS             3432..3722
                     /locus_tag="ctg1_170"
                     /transl_table=11
                     /translation="MNIRPLHDRVIVERQEVESKSAGGIVLTGSAAEKSTRGKVLAVGK
                     GRILENGSVQPLDVKVGDTVIFAESYGTKTEKIDGKEVLILAEHDILAIVE"
     CDS             3776..5410
                     /locus_tag="ctg1_171"
                     /transl_table=11
                     /translation="MAAKDVRFGNDARVKMLEGVNILADAVKVTLGPKGRNVVLDKSFG
                     APTITKDGVSVAREIELEDKFQNMGAQMVKEVASQANDAAGDGTTTATVLAQAIVNEGL
                     KAVAAGMNPMDLKRGIDKAVIAAVEELKALSVPCADTKAIAQVGTISANSDSSVGNIIA
                     EAMEKVGRDGVITVEEGQALQDELDVVEGMQFDRGYLSPYFINNQESGSVELDNPFILL
                     VDKKISNIRELLPVLEGVAKASRPLLIVAEDVEGEALATLVVNNMRGIVKVAAVKAPGF
                     GDRRKAMLQDIAILTGGVVISEEIGLELEKATLEDLGQAKRVSITKENSTIIDGAGDQA
                     AIQGRVAQIRQQIEEATSDYDKEKLQERVAKLAGGVAVIKVGAATEVEMKEKKDRVEDA
                     LHATRAAVEEGVVAGGGVALIRAASKLSSLVGDNEEQNVGIRVALRAMEAPLRQIVKNA
                     GDEESVVANNVRAGEGNYGYNAATGVYGDMIEMGILDPTKVTRSALQFAASVAGLMITT
                     EAMISELPKKDAPAMPDMGMGGMGGMM"
     CDS             5621..6181
                     /locus_tag="ctg1_172"
                     /transl_table=11
                     /translation="MNKPFALMALTAAMAAPAALASTPVMFSSIDNFNTPDANQVAGVR
                     LSALHGKVNEVKGVDFSILGLSETDKTTGVNFGLFFGASKVNQEMTGASLGLLNWNTGN
                     TYGANLGFVNLTHDVKGANLSFVNYSEGNTLVDLGAANFSNTSTVQFGLFNKTEKIEGV
                     QIGLINCADNGFFKCFPIINFAK"
     CDS             complement(6218..7240)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_173"
                     /sec_met_domain="Radical_SAM (E-value: 5.7e-12, bitscore:
                     43.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPHIITRKVISVEQNWLQQLANAISDPLQLLQQLEIDPSPWQDGF
                     EARKLFAQRVPQSFVDRMQKGNPADPLLRQVLPLSAEFEIHPGYSHDPLDEQNNTVPGL
                     LHKYKNRCLLIVKGGCAINCRYCFRRHFPYEDNKGSKAIWQQSLDYIAQNPQLNEVILS
                     GGDPLMAKDHELAWLMERIAAIPHIKRLRIHSRLPVVIPARITDELVELFAQTRLQVLL
                     VTHINHANEINLELKQQMARLRAVNVTLLNQGVLLKGVNDTVDAQVALSETLFDAGILP
                     YYLHVLDKVQGAAHFYVSDDKARQIMAGLIEQVSGYLVPKLTREIGGRPSKTPLDLHLE
                     "
     CDS             7273..7839
                     /locus_tag="ctg1_174"
                     /transl_table=11
                     /translation="MATVSTNEFKGGLKIMLDNEPCVILENEYVKPGKGQAFNRVRIRK
                     LLTGKVLEKTFKSGDTAEVADVVDIDLDYLYNDGEFYHFMNNSTFEQLAADAKAVGENA
                     KWLVENNTCMLTLWNGNPIAVTPPNFVELEVTETDPGVKGDTQGTGGKPATLSTGAVVR
                     VPLFVQIGEVIKVDTRSAEYVGRVK"
     CDS             complement(7953..8315)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fumarate_red_D"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_175"
                     /sec_met_domain="Fumarate_red_D (E-value: 2.3e-46,
                     bitscore: 153.9, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VINTNPKRSDEPVWWSLFGAGGTWFAMITPITVLVLGILAPLGVI
                     DAEALSYERVSSFATSIIGALFIIGTLALPMWHAMHRVHHGMHDLKFHTGVAGKIACYG
                     FATIISALAVVFIFMI"
     CDS             complement(8326..8709)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fumarate_red_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_176"
                     /sec_met_domain="Fumarate_red_C (E-value: 2.7e-49,
                     bitscore: 163.8, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNRKPYVREMKRTWWKDHPFYRFYMGREATVLPLILFTLFLTVG
                     LGSLVKGPEAWQTWLDFMANPLVIAINLVALAGSLFHAQTFFSMMPQVVPIRLGGKLVD
                     KKIIVLAQWAAVAFISLIVLIVV"
     CDS             complement(8712..9470)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 113.8; E-value: 1.2e-35)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_177"
                     /sec_met_domain="Fer2_3 (E-value: 5.1e-34, bitscore: 113.8,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 9.7e-12, bitscore: 42.5,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00029, bitscore: 18.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAQRIQKVDILRYDPANDAEPHMQRFEVPFDETMSVLDAIGYVK
                     DHLDKDLSYRWSCRMAICGSCGIMVNGVPKLACKSFLRDYPEGVKIEPLANFPIEKDLI
                     VDMTPFIERLEAIKPYIIGNDRKPEDGTNLQTPEQMARYKQFAGCINCGLCYAACPQFG
                     LNPEFLGPAALTLAHRYNLDSRDNGKAERMKLINGDNGAWGCTFVGYCSEVCPKHVDPA
                     AAVNQGKVESSLDFVIAMLNPDGSPKKVEA"
     CDS             complement(9470..11278)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 375.7; E-value:
                     1.1e-114)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_178"
                     /sec_met_domain="FAD_binding_2 (E-value: 4.4e-113,
                     bitscore: 375.7, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 4e-39, bitscore:
                     130.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VQILTTDIAVIGAGGAGLRTAIAAAEANPHLEVALISKVYPMRSH
                     TVAAEGGSAAVIKDEDSLDNHFNDTVGGGDWLCEQDVVEYFVANATREMIQMEQWGCPW
                     SRKENGEVNVRRFGGMKVERTWFAADKTGFHMLHTLFQTSMKYPQIKRLDEYFVVDLLV
                     DEGEIQGLIAIHMSEGELVTIKAKSVVLATGGAGRVYHCNTNGGIVTGDGMAMAFRHGV
                     PLRDMEFVQYHPTGLPGTGILMTEGCRGEGGIIVNKHGYRYLQDYGMGPETPVGQPKNK
                     YMELGPRDKVSQAFWHEQQKGNTIKHPLGDVVLLDLRHLGEEYLQERLPFICELAKAYV
                     NVDPAKEPIPIRPTVHYTMGGIETNGECETRIKGLFAVGECASVGLHGANRLGSNSLAE
                     FVVFGRVAGEKAVERAAEFKGWNEKAIAAQVKAVEDRIAALMQQEGDENWATIRTEMGH
                     TMEAGCGIYRQEDLMQETIDKLAELKERYKRISIKDKGKVFNTDLLYAIEVGYGLDVAE
                     AMVHSAILRKESRGAHQRLDEGCTERDDVQFLKHSLAFYQEGQTPKIDYSPVKITKSQP
                     KARLYGEAAEKAAAAEAAGKSVEEQK"
     CDS             11587..12561
                     /locus_tag="ctg1_179"
                     /transl_table=11
                     /translation="MTNSDWMPTASISQLKQRATLLRQIREFFAERNVLEVETPAMSHA
                     TVTDIHLHTFKTEFVGPGYAKGSALHLMTSPEFHMKRLLAAGSGCIYQLGKAFRNEENG
                     RYHNPEFTMLEWYRIGFDHHALMDEMDALLQLVLRCGSAERMTYQEAFLNVLGVCPIEG
                     EMRELKQVAATLGLSDIAEPEEDRDTLLQLLFSIGIEPKIGQITPAFVYDFPASQAALA
                     KINPADPRVADRFEVYFKGIELANGFHELDNPAEQLARFKADNAKRLEMGLTEQPIDYH
                     LIAALEAGLPECAGVALGIDRLIMLALGEDHIDKVTAFPFPRA"
     CDS             12691..13125
                     /locus_tag="ctg1_180"
                     /transl_table=11
                     /translation="MQEYIEFFQQNMILSLAWIGILVALIASIYKSATAAYQEVTATQA
                     TLLINRENGIVVDIRSKDEFKQGHITDAIHILPSDIKAGNLAGLESHKSNPIIVVCKTG
                     QTARESADLLTKAGFEKVNLLKNGLIAWNEANLPLVRGKR"
     CDS             13292..13756
                     /locus_tag="ctg1_181"
                     /transl_table=11
                     /translation="MAEAAQAPQQQFAIQRIYLKDVSFEAPSSPVMFQKEWNPDVKLDL
                     DTQSRELGQGVYEVVLRLTVTVKNAEETAFLCEVQQAGIFSAEQMEAGQLAHCLGAFCP
                     NILFPYARETISSLVVKGTFPQLNLAPVNFDALFMNYLQQQAQEGATANA"
     CDS             13946..14980
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_Gly3P_dh_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_182"
                     /sec_met_domain="NAD_Gly3P_dh_N (E-value: 5.8e-47,
                     bitscore: 156.8, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSETQNHNSYGKPVEMTVIGAGSYGTSLAISLARNGANIVLWGHD
                     AEHMARLDADRANHEFLPGIAFPDTLIVETDLQKAVQASRDLLVVVPSHVFGIVLKSLQ
                     PHLRADSRICWATKGLEPETGRLLQDVAHDVLGDSYPLAVLSGPTFAKELAMGMPTAIS
                     VASPDAQFVCDLQEKIHCSKTFRVYANSDFIGMQLGGAVKNVIAIGAGMSDGIGFGANA
                     RTALITRGLAEMSRLGAALGAQPETFMGMAGLGDLVLTCTDNQSRNRRFGLALGQGKDV
                     DTAQTDIGQVVEGYRNTKEVWMLAKRMGVEMPIVEQIYQVLYQGKDARLAAQDLLARDK
                     KMER"
     CDS             15053..15874
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Hexapep"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_183"
                     /sec_met_domain="Hexapep (E-value: 2.5e-10, bitscore: 37.0,
                     seeds: 216, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQCAHTKVWQTIVAEAREQAEQEPMLASFYHATIIKHDSLKAAL
                     SYILANRLNTASMPAMAVREVIEEAFAADPSISEAAACDICATVNRDPAVSMYSMPLLY
                     LKGYHALQGYRVANWLWRQGRKALATYFQNQISVACQVDIHPAARIGRGIMLDHATGIV
                     IGETAVVEDDVSILQDVTLGGTGKECGDRHPKIREGVMIGAGAKILGNIEVGEGAKIGS
                     GSVVLQAVPPHTTVAGVPARIVGRPQSDKPSLDMDQQFNGRSQTFIGGDGI"
     CDS             complement(15990..16529)
                     /locus_tag="ctg1_184"
                     /transl_table=11
                     /translation="MSLPHVILTVLSTRDATGYDITKEFSASIGYFWKASHQQVYRELN
                     KMGEQGLVTCVLEPQEGKPDRKVYSITQAGRSALGEWFDQPTAHPTVRDEFSAKLMACS
                     VQSAEPYRLQLAELVEESRKLVAHYQEIEAAYYANPAVLDKQQRLERLTLRRNLLVRQA
                     WIQWADEVLAELNAMA"
     CDS             complement(16888..19518)
                     /locus_tag="ctg1_185"
                     /transl_table=11
                     /translation="MNEKYAALKSNVSMLGRLLGQTIQAADGDVILAKVETIRKLSKSA
                     RAGNQADRELLIEEIKNLPNHQLTPVARAFNQFLNLTNIAEQYHTISRHCESHVNELDA
                     IGSLFAKLAQKSVSKFDTAQAIRDLNIELVLTAHPTEITRRTMINKLVKINECLSKLEL
                     SDLSPKERHKTERRLEQLIAQSWHSDVIRQQRPTPLDEAKWGFAVVENSLWHAVPEFLR
                     ELDEQVKSYLGEGLPIDARPVHFSSWMGGDRDGNPFVTHTITREVLLLSRWKAADLYLT
                     DINELVSELSMTKCNEAVRALAGEEHEPYRAILKPVRSLLQETIEILDAKLNGQKLAVK
                     APLQTADQLWEPLYACYQSLHECGMGVIADGSLLDTLRRIKAFGVHLVRLDVRQESSRH
                     AEVISELTRHLGIGDYNQWSEQDKIAFLTTELNSKRPLLPRDWQPSPQVKEVLDTCKII
                     AAQSKDAFGAYVISMARTASDVLAVHLLLQEAGCPYRMDVCPLFETLDDLNNAESVIRQ
                     LMNIDLYRGFIQNHQMVMIGYSDSAKDAGVMAAGWAQYRAMEALVKVGEEAGIELTLFH
                     GRGGTIGRGGAPAHAALLSQPPKSLKGGLRVTEQGEMIRFKLGLPEVAVNSFNMYASAI
                     LEANLLPPPEPKNEWRALMDILSEISCNAYRKVVRGEPDFVPYFRQATPELELGKLPLG
                     SRPAKRNPTGGVESLRAIPWIFSWSQNRLILPAWLGAGEAIQIAINEGHQALLEEMCRE
                     WPFFSTRLGMLEMVYTKCSVSIARHYDERLVEPTLRPLGEKLRAQLQQDIKVVLNVENN
                     ENLMQSDPWGQESIRLRNIYIEPLNMLQAELLYRTRQSELPAPELEEALMVTIAGIAAG
                     MRNTG"
     CDS             complement(19725..20861)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M20"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_186"
                     /sec_met_domain="Peptidase_M20 (E-value: 1.2e-32, bitscore:
                     110.6, seeds: 360, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLPSFLEVYEGLISTSSISSTDARWDEGNEQVIAKLADWLSALG
                     FSIQIEQVAPNKQNLIAKLGSGEGGLLLAGHSDTVPFDEGRWNYNPHALTQANNRFYGL
                     GTADMKGFFAFIYEAVKNVDWSKQTKPLYVLATCDEETTMLGARHFTENAPFKPDYCII
                     GEPTSLVPIRAHKGHVANAIRVTGKSGHSSNPALGVNAIEIMHEVLFALMQLRDRLIKE
                     YHHPGFEIPTPTLNLGHIHGGDSPNRICGCCELHYDVRPLPGISLDGLDNLMRDALREV
                     QQKWPGRIELVPLHDPIPGYECAHDHPFIHGISEICEQEAQTVNYCTEAPFLQQICPTL
                     VLGPGSIDQAHQPDEFLAFEFIDPTVRVLSRAMQKYCF"
ORIGIN
        1 ttacgctttt ttcgcttctg ctgcggcttt ggcgatcgcg gcaaagcctt tcgcatccag
       61 tgatgcaccg ccaaccagcg caccatcgat gtctggttgt gcaaagtaag acgctgcgtt
      121 ttctggtttt acagaaccgc cgtactggat gatcacttgc tcagccactg cagcatcttt
      181 cgcagcgatc agtgcacgga ttgacgcgtg gatacgctgt gcatcatctg ctgtcgcggc
      241 tttacccgta ccgattgccc agattggttc gtaagcgatg atcgcgccgt tcagtgcttc
      301 aacgccgtaa gcatcgatca ctgcgttgat ttggcgagca cataccgctt ctgtttcgcc
      361 cgcttcgttt tgcgcttcag tttcaccgat acagaagact ggcgttaggc cgttttcttt
      421 caggaacgca aatttcttag cgacgaactc atctgattct ttgtggtaat cacgacgctc
      481 agagtgaccg atgatgatgt gcgaagcacc gaaatctttc agcatcgcag gagacatatc
      541 acctgtgtac gcaccactgt tgtgagtatc ggtgttttgt gcacccagga tcagcttgtt
      601 gccgccttct ttgatcaggc gctcagccag atccaaatac attgctggtg gcgcaacgac
      661 aacatcaaca cctgcaacac cttcaagttc tgcattcaaa ccgtttagca ggtcagtgac
      721 catagctttg ctgccattca gtttccagtt acccatcaca acaggacgac gcataggaat
      781 atctccatat ctaatcaatg taaaaaataa actcgcagga ctatagcaga ataaattcgt
      841 cagatcatga ctcgtatcat gtctttatgg gatctcatcg acgcgacaaa tcagcaatcg
      901 agtgatctga gtgacagatt attcggtagt ggctcggttt tttaggttga acttgttatt
      961 actatccctc tctctaggac agaacgattt ttatccaccg ttagcaagga aaaccgaatg
     1021 ccaaacttag tcatggaata ctcaaactca gtcgatgaac gcatcaatgt gcaaggattg
     1081 ctggaagatt tacatcgagc cgcgattgat tcaggactgt ttgaaataag ttcggtaaaa
     1141 tctcgcgcgc tgcgctgcca ccattggttg attggggatg aaggcgacag cgttgatttt
     1201 attcacctca gttttgagtt gctggcagga cgcagtcctg agcaaaagcg agagttatcg
     1261 cgtaagctga tggagattct ggcggcgaaa gccagccatg tgcgcagttt gaccattaat
     1321 attcgagata tggatacaga ctgctttcaa aaagtcatca atcgatgacc ttgtttaggt
     1381 aaaagtcatg tcgttacaaa cactgttgtt ttcttttcag gggcgtattg gtcgccaagc
     1441 tttctggctg tggaatattt gctactacgc catgattgcc ggctttgcaa tgggatcgaa
     1501 tctgctattt cccgatgttg cgcacctgat cttgccggtt tttctgctag tagtcctagt
     1561 gccagatttg gcgattactg ctaagcgttg gcatgatcgt gacaaatcca gctggtggtt
     1621 gctactcaat gtgccgcttg tgattggccg catgacgatt ccggcaggag aattggccgt
     1681 gaatacccaa cccgggatgc tggaaacact tatctcgttt gtggcgttac tgtgtggtgc
     1741 atggattttg gtggagtgcg gatttctttc tggcacggat ggcagtaacc gttttggccc
     1801 cgatccgaag tggatcaaaa aaagctagtc tagcaataag cggtatcaaa tgcgtaagag
     1861 aggaggtttc tctcctctct ttattgtcat ccctaaacca ccgcttttag cggtggtgat
     1921 tgtttcttgc cacttttgcc atctcggctg agagcgttat cgccagccgt cgtcttgaac
     1981 cattctcggg cgaaacggca ccacatccgc gacggtttct tgctgcaaat cgccctccaa
     2041 tgcattgcga aaacgcacca tttgttggct cagttcacgc attaaagtta cgttggcgtg
     2101 tacggggttt ttacattgac ccactacgcg atcaatatgg ctctgctgtg cccaaagcct
     2161 ttgctgcatg gcgtgcgagg cagagaggat catctcttcg cacatctcct tcttaaactg
     2221 atcaaaagca tcaggatggt gctttgcgag ggcgaccaac tcatcaaagg gtggtagcac
     2281 ctgattacag ggttcgggtg agtgtggggg cgtcatgtgg caatcctccg cctttggcta
     2341 aactgatgct tttgtcaaca atactagctt aagcgatttt tgcgcagttc ggcggaacga
     2401 atatcgccct tcttataaat aagacgaaaa gggcgaaaaa cagcatgaga gagattatcg
     2461 cgcggcaata aagtaggtgc agcgacgctc tccggcgaca atgtgttcgc ggcgttcgat
     2521 atggcattct tcgcccaata aacggcgaaa aacattcaat tcggattggc acaggctggg
     2581 acagcgggtg gctgctttgc aaatcgggca gtggttttca atcaaaataa agccgtcggc
     2641 cgtcgactct aactcggcca tatagccttc ttgttcacgc agggtaacca aagcttcgag
     2701 tttttcttgt agagagtggc accccactaa ggcgttgtga taggcagcaa aggtttgggc
     2761 ttcccgttcc gccgccacct tggcgagtcc ttctttacca aaaatatgct cgaccgcatc
     2821 aatcacttga atggtcagct caccatgacg atcggcaaac tgattgtgtc ctttcgcggt
     2881 taaagaccaa tggcgagtcg gacgaccgac cttgactttc acatcatgaa aggccagcac
     2941 accttcttct tccagacttt gtaaatgctg acgagcgccc atggtcgtga tacctaggtc
     3001 ttcagccaac tgtttggcgg ttactgtgcc ttcacgtttg atcgtgtgaa gaatgcggtc
     3061 aaccgttttc atcgtctctt attttcctaa caaggtgtgg tttctaagcg gagccattgt
     3121 gcctgtcacc attcattttg ggtgttgctg gatcggtgcc tctttatact gccgttatta
     3181 tggaatgcga atttaataaa gcaaactatt tactatacct aaggactcgc tagcgggttg
     3241 cccttgatca ccagcaggat cgaaagcgcc accctgccca gagcgatttg ctgtttgaaa
     3301 atgttaaatt aatcacgttt ttttacgctt gcccccttgg gatatgctgc aagttccccc
     3361 acatatgtga cacatgctga tgatcagcgt tttatcaacc atacggaaaa ttaaatcagg
     3421 agagacgacc gatgaatatt cgtccattac atgaccgagt gatcgttgaa cgccaagaag
     3481 ttgaatcaaa atctgctggt ggaattgttc taactggttc tgcggcggaa aaatcaacgc
     3541 gcggtaaagt gttggctgtt ggtaaaggcc gcattctaga gaacggttca gttcaacctt
     3601 tggacgtgaa agtaggcgac accgtgatct tcgcagaaag ctacggcaca aaaacagaaa
     3661 agatcgatgg caaagaagtg ctgatcttgg ctgaacatga cattttggca atcgttgaat
     3721 aattgattct gaatcccaac gaaatcaata actgaattta gaaaggaaat gaaaaatggc
     3781 tgctaaagac gtacgttttg gtaatgacgc tcgtgtaaaa atgctagaag gcgtaaacat
     3841 tctggccgat gcggtaaaag tgaccttagg tcctaaaggc cgtaacgtag ttctcgacaa
     3901 atctttcggt gcaccaacca ttactaaaga tggtgtatca gttgcgcgtg aaattgaact
     3961 ggaagacaaa ttccagaaca tgggcgcaca aatggtcaaa gaagtcgctt ctcaagccaa
     4021 cgacgcggcg ggtgacggta caaccacagc gaccgtactg gctcaagcga ttgtgaacga
     4081 aggcctaaaa gcggttgctg ctggcatgaa cccaatggat ctgaagcgcg gtatcgataa
     4141 agcggttatc gctgcggtag aagagttgaa agcactgtct gtaccttgtg ccgatactaa
     4201 agcgattgcc caagtaggta ctatctctgc gaactcagac tctagcgtgg gcaacatcat
     4261 tgctgaagcg atggaaaaag tgggtcgcga tggcgtgatc accgttgaag aaggccaagc
     4321 gctgcaagac gagctggatg tggttgaagg tatgcagttt gaccgtggtt acctgtcacc
     4381 atacttcatc aacaaccaag aatcaggcag tgtagaactg gataacccat tcatcctgct
     4441 ggtggataag aaaatctcta acatccgcga actgctgcca gtactggaag gcgtagcgaa
     4501 agcctctcgt ccactgctga tcgtggctga agatgtggaa ggcgaagcgc tggcgactct
     4561 ggttgtcaac aacatgcgcg gcatcgtgaa agtggcagcg gttaaagctc ctggctttgg
     4621 cgatcgtcgt aaagcgatgc tgcaagatat cgcgatcttg actggcggtg ttgtgatctc
     4681 tgaagagatc ggtctggagc tggaaaaagc gactctggaa gacctaggcc aagcgaaacg
     4741 cgtttctatc accaaagaaa actcaaccat catcgatggt gctggcgatc aagctgcgat
     4801 ccaaggtcgt gttgcgcaga tccgtcaaca aatcgaagaa gccacttctg actacgacaa
     4861 agagaaactg caagagcgcg tagcaaaact ggctggcggc gttgcagtaa tcaaagtggg
     4921 cgcagcaacc gaagtggaaa tgaaagagaa gaaagatcgc gtagaagacg cgctgcacgc
     4981 gactcgcgca gcggtagaag aaggcgttgt tgcgggtggt ggtgtagccc tgatccgcgc
     5041 agcttctaaa ctctcttctc tggtgggtga caacgaagag caaaacgtgg gtatccgtgt
     5101 cgcactacgt gcgatggaag cgccactgcg tcaaatcgtg aaaaacgcgg gtgacgaaga
     5161 atcagtggtt gccaacaatg ttcgtgcagg cgaaggtaac tacggttaca acgcggcaac
     5221 gggcgtgtac ggtgacatga tcgaaatggg tattttggat ccaaccaaag taacccgttc
     5281 tgctctgcaa ttcgcagcgt ctgttgcggg tctgatgatc accactgaag cgatgatctc
     5341 tgagctgccg aagaaagatg caccagcaat gccagacatg ggcatgggtg gcatgggcgg
     5401 catgatgtaa tcatccccct tagcaggaaa agccggagcc caagctccgg tttttttatg
     5461 ccgtggttat gctaaagcat ggttaagatt ggtcagcatg accaagaaca tgaccataaa
     5521 ctgcgcggaa aaatgacaca atattcacat taccttatgc aagatatgga taatgttgcc
     5581 tagttttccc ccttatccat cctgattgga ggttattttt atgaacaagc cgtttgcttt
     5641 gatggcgctt actgcagcga tggctgcacc agccgcattg gcttcaacac ccgttatgtt
     5701 ctcttctatc gataatttca acacgccaga tgcgaaccaa gttgcgggtg tacgtttgtc
     5761 ggcactgcac ggtaaagtga atgaagtcaa aggggttgat ttctcgattc ttggcctgtc
     5821 tgaaaccgac aaaaccacag gtgtgaactt tggcttattc ttcggtgcaa gcaaagtgaa
     5881 ccaagagatg acgggtgcat ctttgggtct tttgaactgg aacacgggta atacttacgg
     5941 tgcgaactta ggttttgtga acctgactca tgatgtgaaa ggcgcgaact tgagctttgt
     6001 gaactactca gaaggtaaca ctctcgttga cttaggtgcg gccaacttct cgaacacttc
     6061 aacagtgcag tttggcctat tcaacaaaac ggaaaaaatc gaaggcgtgc agattggttt
     6121 gatcaactgt gcggacaacg gcttctttaa gtgtttccca atcattaact ttgcgaagta
     6181 atgatgcaaa aagcgttgcc taggcaacgc tttttcttta ttcaagatgc agatcaagcg
     6241 gtgtcttgct gggcctgcca ccgatttctc gagttaattt cggtaccaga tagcctgaca
     6301 cctgctcaat caagcctgcc ataatctgcc ttgctttatc atcactgacg taaaaatgcg
     6361 ccgcgccttg caccttatcc aacacatgca agtaataagg cagaatgcct gcatcaaaca
     6421 aggtttcgct gagcgccact tgtgcgtcaa ccgtgtcatt gacccctttg agcaacacac
     6481 cttgattgag taaggtgaca ttgacggctc gcaaacgggc catctgctgt ttaagctcaa
     6541 gattgatctc attggcgtgg ttgatgtgtg tcaccagcag tacttgcaag cgggtttgcg
     6601 cgaacagttc aaccaattca tcggtgatgc gcgcggggat caccacgggt aatcgcgagt
     6661 gaatgcgtaa ccgtttgatg tgcggaattg ctgcgatacg ctccatcagc catgcaagct
     6721 catgatcttt ggccattaaa ggatcgccac cggagagaat cacttcgttg agctgtggat
     6781 tttgcgcaat gtaatcgagg ctttgttgcc aaatcgcttt actgcctttg ttatcttcat
     6841 agggaaaatg acggcgaaag caataacggc agttgatggc gcaaccgcct ttgacgatca
     6901 acaagcagcg atttttatac ttgtgcagca agccgggcac ggtgttgttt tgttcatcca
     6961 gtgggtcatg tgagtagccg ggatgaatct caaactcggc actcagcggt aaaacttgcc
     7021 gtaaaagtgg atcggcagga ttgccttttt gcatgcgatc gacaaaactt tgcggcaccc
     7081 gctgcgcaaa cagtttgcgc gcttcaaatc cgtcttgcca tggcgaagga tcgatctcaa
     7141 gttgctgcaa taattgcaga ggatcggaga tcgcgtttgc cagctgttgc aaccagtttt
     7201 gctcaacaga aatgactttt cgggttatga tgtgcggcat tgattttaac tcgaagatag
     7261 taagaggaaa aaatggctac tgttagcacg aatgaattta aaggcggtct caaaattatg
     7321 cttgataacg agccttgtgt cattctcgaa aacgagtatg taaaaccagg taaaggtcag
     7381 gcattcaacc gcgtgagaat ccgtaagctg cttactggta aagttctgga aaaaactttt
     7441 aaatcgggtg acacagcgga agttgctgat gttgtcgata tcgatctgga ttacctgtac
     7501 aacgatggcg aattctacca cttcatgaac aacagcacct tcgaacagct tgctgcagat
     7561 gcaaaagcgg ttggcgagaa tgcgaaatgg ttggtagaaa acaacacttg tatgctgacg
     7621 ctgtggaatg gtaacccaat cgcggtcact ccaccaaact tcgttgagct agaggtgact
     7681 gaaacggatc caggcgtgaa aggtgacact caaggtactg gcggcaaacc agcgactctg
     7741 tctaccggcg ctgtcgttcg tgtacctctc ttcgtacaga ttggcgaagt gatcaaagtg
     7801 gacactcgct ctgcagaata cgttggccgt gtgaagtaat cacctcggtc acaagaaaaa
     7861 accaaccttg cggttggttt ttttatgcgt gtagttttag ccttgcaatc aaaaagctgg
     7921 cctgttgtca gccagctttt tgatgtttca tgttagatca tgaagataaa cacgaccgcc
     7981 agtgcggaga tgatggttgc aaagccgtag caagcgattt tccctgccac accggtgtgg
     8041 aatttcaaat catgcatccc gtggtgaaca cggtgcatgg catgccacat tggcagagct
     8101 aaggtgccga tgatgaacag tgcaccaatg atgctggttg caaagctaga cactcgctca
     8161 tagctcagtg cttcggcatc aatcactccc agtggcgcaa gaatgcccag taccagaacg
     8221 gtaatcgggg tgatcatggc aaaccaagtg ccaccagcac caaacaggct ccaccatacg
     8281 ggttcgtctg aacgttttgg gttggtatta atcacaataa gctccttaca ccacaataag
     8341 aacaatcagt gagataaagg ccacggccgc ccactgtgct agcacgatga tctttttatc
     8401 aaccagtttg ccgcctaaac gaataggcac gacttgtggc atcatgctga agaaggtttg
     8461 cgcatggaat aagcttcccg ccagcgccac taggttgatc gcaatgacga gtgggttagc
     8521 cataaagtcc aaccaggttt gccatgcttc aggccctttc accaaagaac ctaaaccaac
     8581 ggtgaggaac agggtaaaca ggatcaatgg cagaaccgtc gcttcacgtc ccatgtagaa
     8641 gcggtagaaa ggatgatcct tccaccaagt gcgtttcatt tcacgaacat aaggtttacg
     8701 gttactcatc cttaggcctc cactttcttc ggtgaaccat ctgggttcaa catcgcgatc
     8761 acgaagtcta atgaggactc cactttgcct tggtttacgg ctgccgctgg gtcaacgtgt
     8821 tttggacaca cttcagagca gtaacccacg aaggtacaac cccaagcgcc attatcaccg
     8881 ttaataagct tcatacgctc ggctttaccg ttgtcacggc tatcgaggtt gtagcggtgc
     8941 gccagagtga gtgccgcagg gcctaagaac tcagggttta gaccaaactg tggacaagct
     9001 gcataacaca aaccacagtt gatacaacca gcaaactgct tgtagcgtgc catttgctct
     9061 ggggtctgca ggttagtgcc gtcttcaggc ttacgatcgt tacctatgat gtatggtttg
     9121 atcgcttcca aacgctcgat gaacggcgtc atatccacga tcaggtcttt ctcgatgggg
     9181 aagttggcca gtggctcgat ctttacgcct tctgggtaat cacgtaagaa gctcttacat
     9241 gccagttttg gtacaccatt gaccatgatg ccgcaagagc cacaaatcgc catacggcat
     9301 gaccagcggt aagaaagatc tttatctaag tgatctttca catagccaat cgcatccagt
     9361 accgacatag tttcatcaaa cggaacttcg aagcgttgca tgtgtggctc tgcatcgttg
     9421 gctgggtcgt agcgcagaat gtccactttt tgaatacgtt gtgctgacat tatttttgct
     9481 cctctacgct ttttccggcc gcttcagctg cggcagcttt ttcggctgct tcaccgtaca
     9541 gacgcgcttt tggctgcgac ttggtgattt tcactgggct gtaatcgatc ttcggtgttt
     9601 gaccttcttg atagaatgcc aaagagtgtt tgaggaattg cacgtcatca cgctcggtgc
     9661 aaccttcatc aagacgttgg tgtgcgccgc gcgattcttt acgcagaata gcggagtgaa
     9721 ccatggcttc tgccacgtct agaccgtaac ctacttcaat cgcgtatagc aggtcagtgt
     9781 tgaacacttt gcctttgtct ttgatgctga tgcgcttgta acgctctttc aactcggcca
     9841 gtttgtcgat ggtttcttgc atcagatctt cctgacggta gataccacaa cccgcttcca
     9901 tggtgtgacc catttctgta cggatggttg cccaattttc atcgccttct tgctgcatca
     9961 gtgctgcgat gcgatcttca accgctttga cttgtgcggc gatggctttt tcattccagc
    10021 ctttaaactc tgcagcgcgc tcaaccgctt tttcaccagc aacgcggcca aagactacga
    10081 attccgctag cgagttagaa cctaaacggt tcgcaccatg cagaccaaca gaagcacatt
    10141 cacccacggc gaacaggcct ttaatgcggg tttcacattc gccattggtt tcgataccac
    10201 ccatggtgta gtgcacggtt ggacgaattg gaatcggctc ttttgctggg tcaacgttca
    10261 catacgcttt ggccagttca cagataaatg gcagacgttc ttgcaggtat tcttcaccta
    10321 agtggcgcag gtcaagcagt accacatcac ccagtgggtg tttgatggtg ttgccttttt
    10381 gctgctcatg ccagaaggct tgagaaactt tgtcacgcgg acccagttcc atgtatttgt
    10441 tctttggttg acccactgga gtttcagggc ccataccgta gtcttgcagg taacggtagc
    10501 catgtttgtt gacgataata ccgccttcac cacgacaacc ttcggtcatc agaatacccg
    10561 tgcctggtag gcctgttggg tggtattgaa cgaattccat atcacgtaga ggaacaccgt
    10621 gacggaaagc catcgccata ccatcaccag tcacgatgcc gccgttagta ttgcagtggt
    10681 aaacgcgacc cgcaccgcca gtggctagaa caaccgactt agctttaatg gtgaccagct
    10741 cgccttccga catatgaatc gcaatcaaac cttggatttc accttcatca accagcaaat
    10801 ccaccacaaa gtactcatcc aatcgcttga tttgtgggta cttcattgaa gtttggaaca
    10861 gggtgtgcag catgtggaag ccggttttat cggcagcaaa ccatgtgcgc tcaactttca
    10921 tgccgccgaa gcgacgtacg ttgacttcac cattctcttt acggctccaa ggacaacccc
    10981 attgctccat ctggatcatt tcgcgggttg cattggcaac aaagtattca acaacatcct
    11041 gttcacatag ccagtcacca ccgccaacgg tatcgttgaa gtggttatct agactatctt
    11101 catccttgat aactgctgcg gagccaccct cggctgcgac tgtgtgagaa cgcattggat
    11161 aaactttaga aatcagagca acttctaaat gagggtttgc ttctgccgct gcaatagcag
    11221 tacgaagacc agcgccacca gcgccgatga ctgcgatatc tgtggtgaga atttgcacag
    11281 ttatcctcca gtgtgattat tttattttat ggactgagtt cgtttcagta cctagagttt
    11341 tcaaagtatt gatttggaag ttactgagat ggaactcact gactcaacac ctgaccaccc
    11401 attaagtggt aggggtagtg taggagagct tgaagaatga aaaattgatt ctgttgggct
    11461 tttgcttcgg tattgcaaac ttaagcatac tatttgccct atatgtgact ggtgtcacaa
    11521 ttgagtttgg ctttttgttc tgaaagagta caattcgtta tctctgtttc ttgtgatgag
    11581 ccactgatga ctaattccga ttggatgccg accgcatcaa taagccaatt aaaacaacgc
    11641 gcgaccttgt tgcgtcagat tcgtgaattt tttgctgagc gcaatgtgct ggaagtcgaa
    11701 acgccagcca tgagccacgc cacggtgacg gatatccatc tgcacacgtt taaaacggaa
    11761 tttgtcgggc cggggtatgc caagggcagc gcgctgcatt tgatgaccag ccctgaattt
    11821 catatgaagc gtttgttggc cgcgggcagt ggttgtattt accagctggg taaagctttt
    11881 cgtaacgaag aaaatggccg ttaccacaat ccagaattca ccatgttgga atggtatcgg
    11941 attggttttg atcaccatgc tttaatggat gagatggacg ctttattgca attggtgctg
    12001 cgttgcggca gtgccgagcg aatgacttac caagaagcgt ttttgaatgt gcttggcgtt
    12061 tgcccaatcg aaggggagat gcgtgagtta aagcaagtgg ctgcaacgct gggtttaagt
    12121 gatatcgcag agcctgaaga ggatcgtgac accttattac aactgctgtt tagcattggg
    12181 attgagccta aaattggcca aatcacacca gcatttgtgt atgattttcc ggcttcacaa
    12241 gcggcgctgg ccaaaattaa tccggcggat ccgcgcgtgg ctgatcgctt cgaagtctat
    12301 tttaaaggga ttgagctcgc gaacggcttc catgaattgg ataaccctgc cgagcagtta
    12361 gcccgtttta aagcagataa tgccaagcgt ttagagatgg gattgacaga gcaaccgatt
    12421 gattaccatc tgattgcggc gctggaggcc ggtttgccag aatgtgctgg ggtggctttg
    12481 ggtattgatc gtctgatcat gttggcgctt ggcgaggatc atattgataa ggtcactgcc
    12541 tttccgttcc ctcgagcctg atcggattct cagtttgcaa catattcacc ctgttcaggc
    12601 ccagttttaa cgaggtaagc gctcgcgtca tgctgccaac ctcgttatac tccttgtctg
    12661 atttgaatcc ccattgcaag agcacaggat atgcaagagt acattgagtt ttttcagcaa
    12721 aatatgatcc tttcactggc ttggatcggt attttggtcg cgttaatcgc cagcatctac
    12781 aaatcggcca ccgcggctta tcaagaagtc acggccaccc aagccactct gttgattaac
    12841 cgtgaaaacg gcatcgtggt cgacatccgt agtaaagatg aattcaaaca aggccacatt
    12901 accgacgcaa ttcacatttt gccgtcagac atcaaggcgg gtaacttggc tggccttgaa
    12961 agccataaat cgaaccccat tattgtggta tgcaaaacag gtcaaaccgc acgtgaaagt
    13021 gcagatttac tgaccaaagc cggttttgag aaggtcaatc ttcttaaaaa tggcttgatt
    13081 gcttggaatg aagctaacct gcctttggta cgcggtaaac gctaaatcct tagagcaccc
    13141 cgtcggcgct ggtgaaaaga tcagcgcttg acgctcagag ttgtgatatc taccacgtaa
    13201 tggcttgccc acctagtgat cgcacacact ctcagttagt ctcaggacac attgaccttt
    13261 gaaccgaatt atctgaatta aggatgaaat catggctgaa gcagcacaag ccccacaaca
    13321 acagtttgct atccaacgta tctatctaaa agatgtctct tttgaagcgc caagctcacc
    13381 agtgatgttc caaaaagagt ggaacccaga tgtcaaactg gatctcgaca cgcaaagccg
    13441 tgaactgggc caaggcgttt acgaagtggt actgcgcctg acagtgactg tgaaaaacgc
    13501 agaagagacc gcattcctgt gtgaagtaca acaagcgggt atcttcagtg cagagcagat
    13561 ggaagcaggc caattggccc attgcttggg tgctttctgc ccgaacatcc tgttcccata
    13621 cgcacgtgaa accatttcaa gcctagtggt gaaaggtact ttcccacaac tgaaccttgc
    13681 tccagttaac tttgacgcgc tgttcatgaa ctacctgcaa cagcaagctc aagaaggcgc
    13741 aacggcgaac gcataattcg cgcgattgag ttttcagtaa gaataaaatg cacagcgcca
    13801 ccgcgatgtg cattttttgt ttatcactcg agtattggtt tttgcactct ttatctgaga
    13861 cagccttggc gaagaaggtg cagactgcaa tagcctatgt ttgggtatag aatagagcac
    13921 aacttcgtta tcgataggcg gaacaatgag cgaaacacag aaccacaata gctacggaaa
    13981 acctgttgaa atgaccgtga taggtgcggg ctcctacggt acctcactgg cgatctcttt
    14041 ggcgcgcaat ggcgcaaata tcgtcctgtg gggacatgat gcagagcata tggcgcgcct
    14101 tgacgctgac cgcgctaacc atgaattttt gcccggaatt gcttttcctg acactctgat
    14161 tgtggaaact gacttgcaaa aagcggtgca agcgagccgt gatctgctgg tggtagtgcc
    14221 tagccatgtg tttggtatcg tgttgaaaag tttgcagcca cacctgcgtg cggatagccg
    14281 catttgttgg gcaaccaagg ggctagagcc tgagactgga cggctactcc aagatgtcgc
    14341 ccatgatgta cttggtgata gctaccccct tgcggtgctt tctggtccta cttttgccaa
    14401 agagctggcg atggggatgc caaccgcgat ttcagtggct tcgccggatg cgcaatttgt
    14461 atgtgacctg caagagaaaa ttcactgcag caaaactttc cgtgtgtacg ccaacagtga
    14521 ctttatcggt atgcagcttg gcggcgcggt aaaaaacgtg attgcgattg gtgcggggat
    14581 gtccgatggt attggctttg gcgcgaatgc gcgaaccgct cttatcactc gtggcttggc
    14641 ggaaatgagc cgcttaggcg ccgctttagg cgcgcagccg gaaaccttta tgggtatggc
    14701 aggattaggt gatttagtgc tgacttgtac tgacaaccaa tcgcgtaacc gccgttttgg
    14761 tttggcacta ggtcaaggta aagatgtgga taccgcgcaa accgatatcg gccaagtggt
    14821 tgaagggtat cgcaacacca aagaagtgtg gatgctagcg aaacgcatgg gcgttgagat
    14881 gccgatagtt gaacaaattt accaagtatt gtatcaagga aaagatgcgc gactcgccgc
    14941 tcaggatttg ctggcacgag ataagaagat ggagcgttaa tccgcagcgc aagagatgga
    15001 attgaatcga tagggtatag cttgccctat cttgattagg actgagtaag taatgaaaca
    15061 gtgcgcacac accaaggttt ggcaaactat tgtcgctgaa gctcgcgagc aagccgagca
    15121 agagccgatg ctcgccagtt tttaccatgc caccattatt aagcatgaca gtttaaaagc
    15181 ggccttgagc tatattctgg ccaaccgttt gaacactgcc tccatgcctg cgatggcagt
    15241 acgagaagtg attgaagaag cgtttgctgc cgatccgagt atctcagaag cggcggcgtg
    15301 tgatatttgc gcgacagtca accgcgatcc tgccgtctct atgtactcaa tgccgctact
    15361 ttacctaaaa ggctatcacg ctttacaagg ctatcgggtg gctaactggt tatggcgaca
    15421 agggcgtaag gcgctcgcga cctattttca aaatcagata tctgtagcat gtcaggtgga
    15481 tattcaccct gctgcgcgta ttggtcgcgg catcatgctc gatcacgcga cgggaattgt
    15541 gattggtgaa accgccgtag tagaagatga tgtatcgatt ttgcaggacg tcacgcttgg
    15601 cggtacaggt aaagagtgcg gcgatcgtca cccgaaaatt cgggaagggg tgatgattgg
    15661 tgcgggcgcg aaaatcttag gcaacatcga agttggagaa ggggcgaaaa ttggctcggg
    15721 atcggtcgtg ttacaagctg taccgcccca taccacagtc gctggagtac ctgctcgtat
    15781 tgtggggcgg ccacaatcgg ataagccttc tttggatatg gatcagcagt ttaatggtcg
    15841 ttcacagacg tttatcggcg gtgatggtat ctagaggctc tctctatctc agctctcacg
    15901 gtatttaagt gctcattccg cgcttgagca aaaaataaaa aggatgatgg tgacatcatc
    15961 cttttttaca tcggcaggtt tggcttggct tatgccatcg cgttcaattc tgccaacact
    16021 tcgtccgccc attgaatcca tgcttggcga accagtaaat tacgacgtag cgttaaacgc
    16081 tctaaacgtt gctgcttgtc taacacggct gggttagcgt aataagcggc ttcgatttcc
    16141 tgatagtgag cgaccagttt acgcgattct tcaaccagtt cagccagttg cagacggtaa
    16201 ggttctgccg attgtactga acaagccatc aatttcgcac taaactcatc acgcacggtt
    16261 gggtgtgcgg ttggttgatc aaaccactca cctaaagcgc tgcggccagc ttgggttata
    16321 gaataaacct tgcgatctgg tttgccttcc tgtggttcca gaacacaagt cactaaaccc
    16381 tgttccccca ttttattgag ttcacgatat acctgctgat ggctggcttt ccagaagtag
    16441 ccaatgctag cagaaaactc tttggttata tcgtacccgg ttgcatcgcg tgtgctaaga
    16501 acagtaagga taacgtgtgg taatgacatg tcttcaatcc aaaaattaag tcaacataaa
    16561 cttctatcta aacggttgtt gtgcttctaa tggcacgcat atcaacgcat ttaaatacct
    16621 gcagcgcaaa attcggctgc ttatgtcacc ttataaagcc ggttatcacc tagagtggcg
    16681 tatgtctttg catactttaa ctgtgagatt gctttacatt acttatcaca gagggaacgt
    16741 agtatatcta aataataagc ataaagtgga atacaaatat gctgattagt cgaaaaactg
    16801 acattattct caataatgca aaaatgtaaa acaaaaggcc acaaagttgt gaccttttag
    16861 ttttttatac tgacatttag cgatttgtta accagtattg cgcattcccg ccgcaattcc
    16921 cgcaatggtc accatcaagg cttcttccag ttctggagca ggaagttctg attgacgggt
    16981 gcgatacagc agttctgctt gcagcatatt gagtggttca atatagatgt tacgcagacg
    17041 aatcgactct tgtccccaag gatcgctttg catcaggttc tcgttgttct caacgttcag
    17101 cacaacttta atgtcttgct gtaattgagc acgcaatttt tcacccaatg gacgcaaagt
    17161 cggttcaaca agtcgctcat cataatgacg cgcgatgctt acactgcatt tggtgtacac
    17221 catttccagc atgccaaggc gagttgagaa gaatggccat tcgcggcaca tctcttcaag
    17281 tagcgcttgg tgtccttcat taatggcaat ttggatcgct tcacccgcac ctaaccaagc
    17341 aggaagaatg agacgattct ggctccatga gaagatccat ggaatggctc gcaggctctc
    17401 gactccacca gtaggattac gtttggcggg tctggaaccc aatggcagct tgccgagttc
    17461 taattctggt gtggcttgac ggaagtaagg aacaaagtct ggttcaccac gcacgacttt
    17521 tcggtaagca ttacatgaaa tttccgacag aatatccatc agcgcacgcc attcattttt
    17581 aggctctggt ggggggagca agttggcttc caaaatagcg ctggcgtaca tgttaaagct
    17641 gttgaccgcc acttctggta gacccagttt aaagcggatc atttcgcctt gttcggttac
    17701 acgcagaccg cccttcaaac tcttcggtgg ctgagaaagc agtgccgcgt gtgcaggagc
    17761 accgccgcga ccaattgtgc cgccgcgacc atggaataga gtgagttcga tccccgcttc
    17821 ttcgcccact ttcactagcg cttccatcgc tcggtattgc gcccagcctg ccgccatcac
    17881 ccccgcatct ttggcggaat cggaataacc aatcatcacc atttggtggt tctgaataaa
    17941 gccgcgatac agatcaatgt tcatcagttg acggatcacc gattctgcat tgttcaagtc
    18001 atctaaggtt tcaaacagcg ggcaaacatc catacgataa gggcatcccg cttcttgcag
    18061 tagcaggtgc acggcgagga catccgatgc agtacgtgcc atcgaaatca catacgcacc
    18121 aaacgcatct ttggactgcg cagcgatgat cttacaggta tccaacacct ctttgacttg
    18181 aggcgacggt tgccaatcac gtggtagcag tgggcgtttc gagttcagct ctgtggtcag
    18241 gaaagcgatt ttatcttgct cgctccactg attgtaatcg ccgatgccga gatggcgggt
    18301 cagttccgag atcacttctg catggcgtga gctctcttga cgaacatcga ggcgaaccag
    18361 atgcacgcca aaggctttaa tgcggcgcag ggtatcgagc aaggaaccat ctgcgattac
    18421 gcccatgcca cactcatgca gtgattggta acacgcgtag agcggttccc acaattgatc
    18481 tgcggtttgc aaaggggctt ttactgccag tttttggccg ttgagttttg catcaagaat
    18541 ttcaatcgtc tcttgcagca agcttcgtac tggcttgagg atggcgcgat aaggttcgtg
    18601 ctcttcgcca gctaaagcgc gtacggcttc attacacttg gtcatcgaaa gttcgctgac
    18661 cagttcattg atatcggtga gatacaaatc agctgctttc cagcgtgaca gtaacagcac
    18721 ttcgcgagtg atagtgtggg tcacaaaggg gttaccatcg cgatctccac ccatccaaga
    18781 tgagaaatgc acagggcgtg catcaatcgg taaaccttca cctaggtaag atttcacctg
    18841 ttcatctaac tcacgcaaaa actcagggac ggcgtgccac aatgagtttt ctacgactgc
    18901 gaacccccat ttggcttcat ctaatggcgt tggccgctgc tgacgaatca catctgaatg
    18961 ccaactttgg gcaattaatt gctcaaggcg gcgctcggtt ttatggcgct ctttcggaga
    19021 gaggtcgctg agctcaagtt tggatagaca ctcgttgatt ttgaccagtt tgttgatcat
    19081 ggtgcgacga gtgatctcag tcgggtgagc ggtcaatacc agctcaatgt tgagatcgcg
    19141 aatggcttgc gccgtatcga atttactgac cgacttctgc gccagtttag caaacaggct
    19201 accaatcgca tccaactcat tcacgtggct ttcacagtgg cgtgagatgg tgtgatactg
    19261 ctcggcaata ttggtcaggt tcaggaattg gttaaaggca cgagccacgg gagtcagttg
    19321 gtggttagga agatttttga tctcttcgat cagcagctcg cggtctgctt ggttgcccgc
    19381 tcgggcagat ttggaaagtt ttcggatggt ttccactttc gctaaaataa cgtcaccatc
    19441 ggcggcttga attgtctggc cgagtagtcg tcctaacatg cttacgttac ttttgagcgc
    19501 agcgtatttt tcgttcattg tcatcctgcc ttgaaaaaaa attacatcca atgtgagttc
    19561 agttaattac acaatcttga ctattttgtc cagtggactt gcggataaga ctaagattcc
    19621 atttattgtc atccgcattg gtgcagagat tgtttaacta aaaacaccaa attattgaaa
    19681 atttcttaca aaaaagccct gaggttgaac tcagggcgat caatttagaa acaatatttc
    19741 tgcatggctc gtgatagcac gcgtaccgtt gggtcaataa attcaaacgc caaaaactca
    19801 tccggttgat gagcttgatc gatcgagcct gggcctagta ctaaggtcgg gcagatttgc
    19861 tgcaagaagg gcgcttcggt gcagtagttt acggtctgtg cttcttgctc acagatttcg
    19921 ctaatgccat gaataaacgg gtgatcatga gcgcactcat aaccggggat cgggtcatgc
    19981 agcgggacga gttcaatgcg ccccggccac ttttgctgta cctcacgtag agcgtcacgc
    20041 atcaggttat ctaaaccatc taagctaatg cctggcagag ggcgaacgtc ataatgcagt
    20101 tcgcagcaac cacaaattcg gtttgggcta tcgccaccat gaatgtgacc aaggttcagc
    20161 gttggagtcg gaatttcaaa tcccggatgg tgatattctt taattaagcg atcgcgcagc
    20221 tgcatgagag caaacagcac ttcgtgcatg atctcaatcg cattgacccc cagcgctgga
    20281 ttggatgaat ggccagattt accggtcacg cgaatggcat tcgccacatg gcctttgtgc
    20341 gcccggatcg gcaccaagct ggtgggttca ccgatgatgc agtaatccgg tttaaatggg
    20401 gcgttttcgg taaagtggcg tgcaccgagc atggtggttt cttcatcgca cgttgcgagt
    20461 acatacaacg gcttggtttg tttgctccaa tcgacatttt tcaccgcttc ataaataaag
    20521 gcgaagaaac ctttcatatc cgcggttcct aatccataga agcgattatt ggcttgcgtg
    20581 agcgcatgcg ggttgtaatt ccaacggccc tcatcaaacg gcacagtatc actgtgtcct
    20641 gctaataata agccgccttc accgctaccg agcttggcaa tcaagttctg cttattcggt
    20701 gcgacttgct caatttgaat cgaaaaaccg agcgcgctga gccaatcggc taattttgcg
    20761 atcacctgct cattaccttc atcccagcgc gcatcagtcg aactgattga agaggttgaa
    20821 atcaggcctt catagacctc aaggaaactg ggtaacggca t
//
