LOCUS       c00022_NZ_FMWL..       12664 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_FMWL01000004.1 Acidaminobacter hydrogenoformans DSM 2784, whole
            genome shotgun sequence.
ACCESSION   NZ_FMWL01000004
VERSION     NZ_FMWL01000004
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:27:45
            Original ID  :: NZ_FMWL01000004.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 247538
            Orig. end    :: 260202
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12664
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[257538:259526]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..11988
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..12664
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12664
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             114..1226
                     /locus_tag="ctg22_226"
                     /transl_table=11
                     /translation="MAAEIAAVLAAVFEDLTSLTGGLGGFVGLFDPGGPGGPGGPGGWQ
                     IDLLLWLQSMRHPALTLFMGGVTMLGDDLFYVAVLGLMYWKAFLGIDEISGTNGRVYLN
                     GRGKSDGGFSRQDIMALMNLVVLSVLLNIVIKQVIAAPRPFEVVQALEGLWVFTAGSAS
                     FPSGHAQTAATFWVALLSSGKFFETGRQGGSWRPGRLGTSLLMVALISISRLYLGVHWP
                     QDVLAGAALGTILGFSGPVLSKNFNRWSLIPILALAATGIFVYQDDGAVQLICLLAGAV
                     FGHWKSSRGERSQRSVNSDRDPSVAALALTFAFGLVAIAGAYLATTWLLTLAVLPELLV
                     KAFATVETGLMVTWGVPSLLDFKRYPGRCG"
     CDS             1338..1811
                     /locus_tag="ctg22_227"
                     /transl_table=11
                     /translation="MKEIFFAGGCFWGVEEFFSRIEGVEDTEVGYANGHTEDPDYKQVC
                     TGNTGYAETCKIKYDPEVIGLEILLDKLFSVIDPTLIDRQGPDIGNQYRTGVYYVEESD
                     RPVIEAYFDKARSNYDLPIRTELEPLRNFYEAEEYHQDYLKKNPGGYCHIKLD"
     CDS             1934..2791
                     /locus_tag="ctg22_228"
                     /transl_table=11
                     /translation="METKQLQYFHVDAFTEVPFAGSPTGVILMDEALPDEVMQAIAAEL
                     NHSETAFVAKLPPEAARSQCAFYALRWFTPEVEVQLSGSATLAAAKVLQQELGENSPCI
                     VFKTLYGEIFTRMRDEDITITLPLDDYEPLDPSEQVLWYLGINNYQRAVYSRNLKKLII
                     EVDDELTLSRIKPDFNKLRGIDLDFELGGLSITCRSSNPLDYDFASRYFNPWIGVDEDT
                     ITGSIHTVLALYWSRELKKQHLVAVQASKRAGRLILDVTQGNVDITGCAYVAIEGQIRL
                     PIKE"
     CDS             complement(3046..4215)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 53.6; E-value: 5.6e-17)"
                     /gene_kind="transport"
                     /locus_tag="ctg22_229"
                     /sec_met_domain="MFS_1 (E-value: 2.1e-16, bitscore: 53.6,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKTNKKWMIATAFASIFGLAISTGIRGILVPNFIDSFGVTDGQIG
                     MLFTATTFFSVFAIYYGSQWGERVGLKKVILSAQVVSGLLFLAVSQVSGYTLFVIGYSM
                     IQFCISLLIISLNTMATVIQVRYPAILVNLVHFFFGLGLTFSQRAGGELVARGFDWVDL
                     FRMVGILYFLTAAMTFFMKEPNTILRAERVKLRTLPNKGYLALLAMGVGFYVASELQTA
                     NWIVYYLKTMYDFAEDRAGGVSAIFFGLFTIGRLLGGVIAEKLGYVRSVVVFTVSASVL
                     YVSGMLLGELGLYLIAGAGFFYSLVFPMVTIILARDFGQFRATAIALVSTAGNLMTLIT
                     SLLIGGMTDWIGIGTGYWVIPVSIVLSAASFMVAFGRQRTMGVRPAEKF"
     CDS             4538..4741
                     /locus_tag="ctg22_230"
                     /transl_table=11
                     /translation="MSAFKKPIEISRSERNNRDVTIHLFNLNILSHNQGPAFAELLKLA
                     VLTAFAYAVSKFVKGEPLFKNK"
     CDS             4757..5023
                     /locus_tag="ctg22_231"
                     /transl_table=11
                     /translation="MLVVRKNKYEELEQLRRKTNIIRLLEGILIGLAVGALLALFLTPW
                     DGQENRRYFKGQLGDLKDKCRGMWGKCCSEDEEYFEDEDVLED"
     CDS             5191..5760
                     /locus_tag="ctg22_232"
                     /transl_table=11
                     /translation="VPATVKYNHSIVIDRPRGKVLELMTETEHLPKWQRGLAKVETLEG
                     EPFTLSAKTRLVFDTGKKSLEMTETLVDMRLPDAYTAIYETEELWNRVTNMFSEVDGKT
                     LWTTENEFVFSGMMRYLGPRMKKSFIKRTEYEMARFKEFVETHDQPEPLESDLQPASQE
                     TLEPHEAFEPHEAFKSHEPLDTTQHE"
     CDS             5776..6600
                     /locus_tag="ctg22_233"
                     /transl_table=11
                     /translation="VELYKKSGQPLKVLNLLFFAGTLAVNALANILPFNGLTTGEVSDD
                     FRNLFTPAPITFSIWGLIYLLLGLFVLYQLGWTSAGKRGVSRVTADIGPLFIISSVANM
                     AWIYFWHYQELALTLLFMLVLLVSLIGIYLRLQDTKRERYGMMTVLVDLPFSIYLGWIS
                     VATIANFAAFFVSIEWNAFGLSPVLWTVTVMAVAVLLGVLAIYKNREYAYALVIVWAFV
                     GIYLQHRDYWAGQYPAIQYAAIGGAAVLVVFGLLTAFGFGQGRRSRKTSRRY"
     CDS             complement(6825..8546)
                     /locus_tag="ctg22_234"
                     /transl_table=11
                     /translation="MCGLNDGTTDRCSLRRRAGLILLLLITGISLFFSGCIRNQEAPNG
                     LSGTETSADSETDEQTVDGDERPSANAPLVSADPLQSKPVPDLAALPVIKSPEKFHALY
                     LNPIEVLTTQEEVPGTLWKSTVQISGLRDEIVQKAINEDLSRLYSALMEDYVPPYRGIY
                     QRIPPGTPPVTMNLNAFVAFNFENLLSVVIYCDKTYDIQSSDGEESTKPKMQEYASRVE
                     TRNYDLRTGRDVALAELFSDPPLAMEKVNSEVAKLLSAQQADEEPGFDMGMRWAPALTT
                     AFKGLTPDQKFYLQPTGITLVLDHHTPAFDTGFHPAHLSLSFAAFEGGLALRQRFASSP
                     GANIYRDTGPRDQQFVQSGTFSSEHLAAGDEGGFNPTVNTHLSYRYPTDLPAPLLTLAT
                     TAVEESRQFLKTLEFTGTLRPGEEPYCEISLDVIKVGPFTTLRHAVYTNAPVKDAASDE
                     GVRPAINDAFSLRKSLPQSHAQNPIFFTSFYADGRQITLEDCFQPGLDYDALLTDAYNK
                     QALQYGYPTVEKSQLANPMLSIGHTGLECYFPELGDYGYMNLPYEDLGSEHLTIFD"
     CDS             complement(8530..9606)
                     /locus_tag="ctg22_235"
                     /transl_table=11
                     /translation="MSGRSTKRRRNILLVETGISEAIPFRRITTIIITVLIILTALVFG
                     GCSREQEGAVDGGQTQAENGGENGGQTSSESGGDTEGNDGGQTSSELRPTFTPETYPRI
                     DGSTVTIPLSEAVAAELMDMSVEEARPYILHNKTHQAYVNLIEKKADLIFVTYPSAEEF
                     ALAKSSGVVLDIIPVVSEAFVFLVNAENSVAGLTPSELQKIYTGEITKWSEVGGANLDI
                     IPYQRPLNSGSQTGFLDMVMAGLTPMEPPMEQVIAEMGMLIDAVASFENGEGALGYSYY
                     YFVMDMWGAENIKLLEIDGVAPTPEAITAGTYPFTTAYYAVVRHDEPEDSPARQVVDWL
                     LSSGGQTLAEETGYVRIK"
     CDS             10001..11158
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_236"
                     /sec_met_domain="HGD-D (E-value: 5e-86, bitscore: 283.2,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQQNSLPEIFESFADARKQGFLAAKAVKDAGKNLIGYYCTYTPV
                     EVIMAAGAVPVGLCATSDETIPESEKVLPRNLCPLVKSSYGFAVTDKCPYFYFSDLIVG
                     ESTCDGKKKMYELLNEVKPTHVLQLPNENKSERSLDYFKEEVFTFKERLEKEFNITITN
                     EDLKKAIQLKNRQRETIKEFYNLMSLTPPPISGLDVHKALYGSEFKFDKEAQIQEMQAL
                     TKQIYETYRTQGSKIKPEAPRILITGCPIAGATEKIITAIEENGGVVVTYENCFGTKAV
                     EEMIDESLDPIEGIARKYLNTPCSVMSNNQDRLDKLSELIERFKADGVVDVVLQACHTY
                     NIEGFSVKRHVKEKHNLPYIALETDYASSDTGQLKTRLGAFIEML"
     CDS             11227..11988
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: FGGY_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_237"
                     /sec_met_domain="FGGY_C (E-value: 1.9e-07, bitscore: 24.9,
                     seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 1.8e-59, bitscore:
                     195.2, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHMGIDIGSVCAKGAAIRDGRMEKVMLPTGWNIKETASLLKMAL
                     LEKMDAEDSAVRGVVATGYGRVSIPYADKKVTEITCHARGAVHLNPATRTIIDIGGQDS
                     KLISIDADGRVQDFVMNDKCAAGTGRFLQVMAHVLEIEVDDLDQLATQGDPVTINAMCT
                     VFAESEIISLLAQGTEKGAIAAGILSSISQRVQHLSSRISVQDQLLFTGGVSNSGYLRQ
                     LLTSKLNFEVHHHPDAQFAGAIGAALLAQES"
     CDS             complement(12107..12664)
                     /locus_tag="ctg22_238"
                     /transl_table=11
                     /translation="RYLEGKLKLKMNAQKSKVVSVLAIKHFKFLGFCLGKNKKGVYIRA
                     HRESLAKAKRKLRQLTRRNQGRNVRMVMENVKSFIRGWLGYYYVADIKRTLMSWNEWLR
                     RRLRMYVWKQWKKPRTRIMNLKKLGIPEWQAYQWGNTRLGYWRIAGSAVLNRSITNEKL
                     ALAGYYDFPAQYEQLRLMHSSG"
ORIGIN
        1 agctcgaagc agctgtctaa gcgcggcggc aacctgatgg tggaggtcct gggagaccgc
       61 gtcaagctga tgggtaaggt tgtttcttat atggaaggca ctattacgat ttaatggcag
      121 cagagatagc tgctgttttg gcagccgttt ttgaggattt gacaagcctg actggtggtc
      181 tcggtggttt tgttggcctc tttgatcctg gaggtcctgg aggtcccggc ggccccggcg
      241 gctggcaaat cgatctgctg ctgtggcttc agtctatgcg tcatcctgct ctgacgcttt
      301 tcatgggcgg ggtgaccatg ctgggggacg acttgtttta tgtcgctgtt ctggggctga
      361 tgtactggaa ggcttttctg ggcatagatg agatcagtgg gacaaacggc cgtgtctact
      421 taaatgggcg tgggaaatct gacggcggtt ttagccgaca agacatcatg gcgctcatga
      481 acctggtggt gctttctgtg ctgctcaata ttgtcataaa gcaggttatc gcggcaccac
      541 ggccctttga agtcgtccag gcgcttgaag gtctttgggt gtttaccgcc ggcagcgcct
      601 cgtttccgag cggccatgcc cagacggcgg cgaccttttg ggtggcactg ctttccagtg
      661 gcaagttttt tgaaactgga agacagggcg gatcttggcg gcctgggcgt cttggcactt
      721 cactgctgat ggtggcgctg atcagcatct cccggcttta ccttggcgtt cactggcctc
      781 aggatgtcct ggcgggcgcg gctcttggga caattctcgg tttttcaggt ccagtgcttt
      841 caaaaaattt taaccgatgg tcactgatcc ccatcctcgc cctcgcagcc actggtatct
      901 tcgtctatca ggatgacggt gcggtacagc tgatctgtct gctggcgggc gcggtttttg
      961 gccactggaa aagcagcaga ggggaaaggt cccagcgtag tgtaaattca gaccgcgatc
     1021 cttcagttgc cgcactcgcc cttacttttg cctttggctt ggttgccata gcgggcgcct
     1081 atttggcaac aacctggctg ttgacactgg ctgttcttcc agagttgctt gtcaaggctt
     1141 ttgccactgt tgaaaccggt ctaatggtca cttggggtgt gccatcactt ttggatttta
     1201 agcgttatcc gggacgctgc gggtagtcgc ttcatttttt tagtactttg ggggtcagac
     1261 cccgtttgag aacccgtttg agaccccgat tgttttgcga tttttaccgc aagctcaatt
     1321 tagaggaggc aattttcatg aaagaaattt tctttgccgg cggctgtttt tggggcgtcg
     1381 aggaattttt ctcgcgaatt gaaggcgtcg aagataccga ggtcggctat gccaatggtc
     1441 acactgagga tcctgactat aaacaggtct gcaccggaaa cactggctat gcggaaacct
     1501 gcaaaatcaa atatgaccct gaagtgatcg ggcttgagat tttgctcgac aagctgttca
     1561 gcgttattga cccgaccctg atcgacaggc aggggccgga cattgggaat cagtaccgga
     1621 cgggggtcta ctatgtagag gaatcagacc gcccagtgat tgaagcttac tttgacaagg
     1681 cgcgttcaaa ctatgacctg ccaattcgca cagagcttga gcccctcagg aatttttacg
     1741 aggctgagga atatcaccag gactacttga aaaagaaccc cggtgggtat tgccacatta
     1801 agctggatta atttacaggg cttatggctg aagtcagtgt ggtaaatttc cacagtggtt
     1861 tgggcgtctc ctttttttga acctaagcct gataattggc ttctcctttt ttaaaagaac
     1921 ggagtgatct cccatggaaa caaagcagct ccaatacttt catgtcgatg cattcacgga
     1981 ggtcccgttc gctggcagcc caaccggtgt cattctcatg gatgaggcac tgcctgatga
     2041 ggtgatgcag gccatagccg cagagctcaa ccattccgaa accgcatttg tggcgaaact
     2101 gccgcctgaa gcggcccgca gtcagtgcgc tttttacgcc ctgcgctggt ttacgccaga
     2161 ggtagaggta cagctgtcag gctctgccac cctggccgct gcaaaggtac ttcagcaaga
     2221 gctcggtgaa aatagtccat gcatagtatt caagaccctt tatggagaga tttttaccag
     2281 gatgagggat gaggacatca ccataactct tccgcttgat gattatgaac ccttggaccc
     2341 ttcagagcaa gtgctctggt acctgggcat caacaattat cagcgggccg tttatagccg
     2401 taaccttaaa aagctgatta ttgaggtaga tgacgagctc accctttcca gaatcaagcc
     2461 cgacttcaac aagctccgcg gtattgacct ggactttgag ttaggaggcc taagcattac
     2521 ctgcaggagc agcaaccctt tggactacga ctttgcctca cggtatttca atccttggat
     2581 aggcgtagac gaggacacga tcacaggctc tatccacact gtactggccc tttattggtc
     2641 cagagagctt aaaaagcagc atctcgtggc tgtacaagcc tcaaagcgcg caggtcggct
     2701 gatcctggat gtcacacaag gcaatgtcga cataacgggt tgtgcctacg tcgccattga
     2761 aggacagatt cgcctgccaa ttaaggaatg aacggtgacg cgttcagcgc cggaaaatga
     2821 tctttcagca tcacaaaaca aaaagataaa cacgaagtaa aaagccccta agaaaaagct
     2881 tgccaagggt tcgaacctgc agcaaatgcc ttttcaaaga ggctttttta ttttgtccag
     2941 cgaagagaca gaactgagtg ggtctgaccc cctcgtttcg aaaaaagcag gtctgacccc
     3001 ctcggaactt tcacgcgggt ctgaccccca tgctgtcccc atacttcaaa acttctccgc
     3061 aggtctgacc cccatggttc tttgtcgccc aaaagccacc ataaaggaag ctgctgacag
     3121 tacgattgag accggaatca cccaatagcc ggttccaatc ccgatccagt ccgtcatacc
     3181 gccaatcaga agactggtga tgagagtcat caggttgcct gccgtggata ccagcgcgat
     3241 ggctgttgcc cgaaattgtc cgaaatcgcg ggcgaggatt atggtgacca tcgggaaaac
     3301 caaggaatag aagaagccgg ccccggcaat caggtacagg ccgagctcgc ctaacagcat
     3361 cccgctgacg tagagtaccg acgcgctcac cgtgaacacc acgacgctgc gcacgtatcc
     3421 cagcttctcc gcaatcacac ctcccaggag gcgccctatg gtaaacaggc caaaaaatat
     3481 cgcgctgacc ccgccggccc ggtcttccgc aaagtcgtac atggtcttga ggtaatagac
     3541 aatccagttg gcggtctgga gctctgaggc gacatagaag ccaacgccca tggccagcag
     3601 ggccaggtag cctttgtttg gaagggtgcg gagcttgact ctttctgccc gcaggatagt
     3661 gttgggttct ttcatgaaga aggtcatggc agcagtgaga aaatacagaa tacccaccat
     3721 gcggaacagg tccacccagt cgaaccccct ggcgacgagt tcgccaccgg cccgctggct
     3781 gaaggtgagg cccagtccaa agaagaagtg gaccaggttg accaggatgg caggataacg
     3841 cacctggatc acagtggcca tagtattcag ggaaatgatg agcagcgaga tgcaaaactg
     3901 gatcatgctg tagccaatga caaagagcgt atagccgctg acctgggaaa cggcgaggaa
     3961 gagcaggccg ctgacgacct gggctgacag gatgactttt ttaagtccga ccctttcgcc
     4021 ccactggctg ccgtagtaga tggcgaagac gctgaagaag gtcgtcgctg taaagagcat
     4081 gccaatctgt ccgtccgtga cgccaaagct gtctatgaag ttggggacca ggatgccccg
     4141 gatgcctgtc gaaattgcca ggccaaagat ggatgcgaaa gccgtggcaa tcatccattt
     4201 cttattggtt ttcaagtgcg tgtacctccg gcttggaatt ttgtgtgcta tggagatttt
     4261 ggtgcgggac tgtccccaac caaataatgg gaacgtttgg tgcgggactg tcccgcacca
     4321 aacatgagag gtctgacccc atcatgactc ctcatgttca tagtaagttg taaacaggat
     4381 gccgtcaaag acatttagcc ttttttttac gcactgactt taccaatgaa gattttttag
     4441 tattttccct gattttctac gattttctgc caatttcacg ctttcagtgt ttatttggaa
     4501 gggggataag ggtatctatg gtctgagagg tgattatatg agcgcgttta agaaacccat
     4561 tgaaatcagc aggagtgaaa ggaacaacag ggatgttacc attcatctgt ttaatctgaa
     4621 catccttagc cataatcagg ggccggcgtt tgctgagctt ctgaagcttg cagtgttgac
     4681 ggcattcgcc tatgcggtaa gcaaatttgt caaaggtgaa ccactgttta aaaataaata
     4741 aaagggagtg acgcaaatgc tagttgtcag aaagaataaa tatgaggaac ttgagcagtt
     4801 gagacgtaag acgaatatta tacgcttgct ggaaggtatt ttaattggat tggctgttgg
     4861 agcgctgctc gctttatttt tgacaccgtg ggacggtcag gaaaacaggc gatacttcaa
     4921 gggccagctg ggcgacctca aggataagtg tcgtggcatg tggggaaaat gctgtagcga
     4981 agatgaggaa tatttcgagg atgaggacgt gctggaggat tagtgggact attaacggga
     5041 ccaatcacgg gactattaac ttccaagtgc cgccaccgtc agattttgtg ataaaatata
     5101 atctgcagta taagtgaatt ttggcggcat gctctgccgc tgtctttttg tgggtggggg
     5161 accatcggca aaaaaataaa aaaggaaggg gtgcctgcca ccgtgaaata caatcattca
     5221 atcgtcattg accggcccag gggcaaggtt ctggagctca tgacggaaac ggagcacctg
     5281 ccaaagtggc agcggggtct ggccaaagtg gagaccttag agggggagcc cttcacgctg
     5341 agcgcgaaga cgcggctcgt cttcgacacg ggcaagaagt ctctggaaat gacggaaacc
     5401 ttggtcgata tgcgccttcc agatgcctac acggctattt acgaaactga ggagctctgg
     5461 aaccgagtca ccaacatgtt ttctgaggtc gacggaaaaa ctctttggac gactgaaaac
     5521 gaattcgtct tcagcggcat gatgcgctac cttggaccgc gcatgaaaaa gtcctttata
     5581 aagcgcaccg agtacgaaat ggccaggttt aaggaatttg tcgagaccca tgaccagccc
     5641 gagccgctgg aatccgactt gcagcctgcg tctcaagaga ctttggagcc acatgaagct
     5701 ttcgagccac atgaagcttt caagtctcac gaaccgctcg acacaactca acacgaataa
     5761 gattggggtg atgacgtgga gctatacaag aaatccgggc aaccgctgaa agttcttaat
     5821 ttgctttttt tcgcagggac tctggcggtg aacgccctcg cgaatatttt gccctttaac
     5881 gggttgacca cgggggaggt ttcggatgat ttcagaaacc tattcacgcc ggcgcccatc
     5941 acgttttcca tttgggggct catttatctg ctgttaggac ttttcgtcct ctatcagctg
     6001 gggtggacgt ctgcggggaa acggggcgtc tcccgggtta cggcggatat tgggccgctg
     6061 ttcatcatca gctccgtggc caacatggcc tggatctact tctggcatta tcaggagctg
     6121 gcgctgacgc tgctgttcat gctggtgttg ctggtttccc ttattggcat atacctcagg
     6181 ctgcaggata caaagcggga gcgctatggc atgatgactg tgctggtgga cctgccgttt
     6241 tctatttacc tggggtggat cagcgtcgcg accattgcca actttgcggc atttttcgtc
     6301 agtattgagt ggaacgcatt tggactgtca cccgtgcttt ggacggtgac cgtgatggcc
     6361 gtagccgtgc tgctgggcgt gctcgccatt tacaaaaacc gcgaatatgc ctatgcgctg
     6421 gtgatcgttt gggcttttgt gggaatctac ctccagcata gggattactg ggcagggcag
     6481 tatccagcga ttcagtatgc agctataggg ggggcggctg tactcgtggt gtttggactg
     6541 ctcacggcct ttggctttgg gcaggggcgg cggagccgta agacttcgcg ccggtattga
     6601 tttgagataa ttattaagtt caaaaatgtt tcaaggccgt cggcagagtg ttctgcttcg
     6661 acggccttgc tttttttgtt tagtggatgc gggggatggg gggcgaatga ccattgccaa
     6721 aaaaatattt taaggatttt gccgatggtc ccgctttcca caacttcgca ggtctgaccc
     6781 cctcggtatg ccataggaca tttatgcagg tctgaccccc tcggttaatc aaaaatcgtc
     6841 aaatgttcgc tgcccaaatc ctcataaggg aggttcatat agccgtaatc gccaagctca
     6901 gggaaataac actcaaggcc cgtgtgacct atggagagca tggggtttgc cagctggctt
     6961 ttttcgacgg tgggatagcc atactgaagc gcctgtttat tgtaggcgtc ggtgagaagg
     7021 gcgtcgtagt cgaggccggg ctggaagcaa tcttccaggg tgatctggcg accatcggca
     7081 taaaagctgg tgaaaaagat gggattctgg gcgtggcttt ggggcaatga ttttcggagt
     7141 gaaaaggcgt cgtttatagc aggtctgacc ccctcatcac tcgcagcatc cttcacgggc
     7201 gcattggtat aaacggcgtg gcgcagcgtg gtgaaggggc cgaccttgat gacgtccagg
     7261 gagatttcgc agtagggctc ctcgccaggc ctgagggtgc cggtaaattc gagggttttc
     7321 aagaactgcc gggactcctc tacagctgtc gttgccaagg tgagaagcgg ggcgggaagg
     7381 tcggtgggat agcggtaact caggtgggtg ttgacagttg gattgaaccc gccttcatca
     7441 ccagcagcga ggtgttcgct tgagaaggtg ccggactgga cgaactgctg gtcacggggg
     7501 ccggtgtcgc ggtagatgtt ggcgccggga ctgctggcaa agcgctggcg gagtgccaga
     7561 ccaccttcaa aagcagcgaa ggagaggctt agatgggcgg ggtggaagcc ggtgtcaaag
     7621 gcaggggtgt ggtggtcgag gacgagagtg atgcccgtgg gctggaggta gaacttctgg
     7681 tccggggtca gacccttgaa agcggtggtc agtgcagggg cccagcgcat gcccatgtca
     7741 aagccgggct cctcatccgc ttgctgggcg ctgaggagct ttgcaacctc gctgtttacc
     7801 ttttccatgg caagcggcgg gtccgaaaag agctctgcca gtgcgacatc ccggccagtg
     7861 cgcaggtcat agttgcgtgt ttcgacccgt gaggcgtatt cttgcatctt gggtttcgtg
     7921 ctttcttcac cgtcactgct ttgaatgtca taagtcttgt cgcagtatat gacaacggaa
     7981 agcaggtttt cgaaattaaa ggcgacaaag gcgttaaggt tcatagtgac agggggcgta
     8041 cccggcggaa tccgctgata gatgcccctg tagggcggga catagtcttc catcagggcg
     8101 ctgtataatc tgctgaggtc ctcgttgatg gctttttgga cgatttcgtc ccggaggccg
     8161 ctgatttgaa ccgtgctttt ccaaagggtg ccagggactt cctcttgggt ggtcaggact
     8221 tcaatggggt ttaaatataa ggcgtgaaac ttctccgggg atttaatgac agggagcgcg
     8281 gcgaggtccg ggacaggttt ggactggagg gggtcagcgc taacaagagg ggcgtttgcc
     8341 gatggtcgct catccccatc cactgtctgt tcatcagtct cagagtcagc tgaagtctca
     8401 gtgccggaca gcccgttggg tgcctcttga tttctgatgc agccgctgaa gaaaagggaa
     8461 atgccggtga tcaacaacag gaggatcagg cctgccctcc ggcggaggct acagcggtca
     8521 gttgtgccat catttaatcc gcacatagcc agtctcctcc gcgagggtct gacccccact
     8581 gctcaaaagc cagtccacca cttgtcgtgc cgggctgtcc tctggctcgt catgccgtac
     8641 cacagcatag taggcggttg taaaagggta ggtgcctgcc gtgatggcct caggcgtcgg
     8701 cgccacgcca tcgatctcaa gcagcttgat gttctccgca ccccacatat ccatgacgaa
     8761 ataatagtag gagtagccca gagccccctc accattttca aagctggcaa cagcatcgat
     8821 cagcatgccc atctcagcta tgacttgctc cataggcggt tccatggggg tcagacccgc
     8881 catgaccata tccaaaaatc ccgtctgact gccagagttc agcggacgct gataggggat
     8941 gatgtcgaga ttcgctccac ccacctcgct ccattttgtg atctctccgg tgtagatctt
     9001 ttgaagttct gagggggtca gacctgctac ggagttctcc gcattgacca gaaacacaaa
     9061 ggcttcactg accaccggaa taatatcgag aaccactccg gaagacttag ccaaggcaaa
     9121 ttcctctgcg gaagggtagg tgacgaaaat aaggtcggcc ttcttttcaa tcagattgac
     9181 gtaggcctga tgagttttgt tgtgaagtat ataaggacgc gcttcttcga cagacatgtc
     9241 catcagctca gcagcaacag cctcggagag tggaatcgtc accgtggagc cgtcgattcg
     9301 gggataggtt tcgggcgtga aggtggggcg aagttccgag gaggtctgac ccccatcatt
     9361 cccctcggta tcgccgccag attccgagga ggtctgaccc ccgttttcac ccccgttttc
     9421 cgcctgggtc tgacccccgt ccaccgcacc ctcctgttcc cgactgcagc cgccaaacac
     9481 taaggccgtc aagattatca aaacagtgat aataattgtc gtgattcggc gaaaagggat
     9541 ggcttcagaa attcctgttt caacaagcaa aatatttctg cgtcttttcg tagaacgacc
     9601 tgacatttca aacgcctcca tagtttctgc tcaagcaggg taagttgaac aaacaaattg
     9661 ttaaattctt atctaagaga tccaatttaa ctatactacc ttcagctgca aacgcaagac
     9721 ctttcagaac ccccttacca acccaaaagc cttgccgata gtcacccaac ccaccccgcc
     9781 gctatactgg aaacacccac catcatccta tttttttatt gatccccgtt atcaattgaa
     9841 tctttcaatt tcacgccttt cacacaacac ggtaaactgt tggtggctgc gccatatttc
     9901 aataattaaa aaatctctta gtcagcggtt tatcaaagac aataattaga acgtctcatc
     9961 cgtcaacaca aaaaactatc ccaacccagg aggtctcaca atgtcccaac aaaactcact
    10021 gccagaaatc ttcgaaagct ttgccgatgc tcgtaagcaa ggcttcctcg ccgccaaggc
    10081 cgtcaaagac gccggcaaaa atctgattgg ctattactgc acctacaccc ccgtcgaggt
    10141 catcatggcc gccggcgccg tccccgttgg cctctgcgcc accagcgacg aaaccattcc
    10201 agagtccgaa aaagtcctgc cgcgcaactt atgcccactc gtcaaatcca gctacggctt
    10261 cgccgtcacc gacaaatgcc cgtacttcta cttctctgac ctcatcgtag gcgaaagcac
    10321 ctgcgacggc aaaaagaaaa tgtatgagct gctgaacgaa gtcaaaccga cccacgtcct
    10381 tcagctcccc aatgaaaaca aatccgagag atctctggac tacttcaaag aagaagtgtt
    10441 tacattcaaa gaacgccttg aaaaagaatt caacattacc atcacaaacg aagatcttaa
    10501 gaaagccatt caacttaaaa accgccaaag agaaaccatt aaggaattct acaacctcat
    10561 gagcctcacg ccgccgccaa tcagcggact cgacgtccac aaagccctct atggttctga
    10621 attcaaattt gacaaagaag cacagattca ggagatgcag gcactcacaa agcaaattta
    10681 cgagacctac agaacgcagg gcagcaaaat aaaaccggag gccccaagga tcctcattac
    10741 cggctgccca attgccggcg ccaccgaaaa aatcatcact gccattgaag aaaacggcgg
    10801 tgttgttgtc acctatgaaa actgctttgg caccaaggcc gtcgaggaaa tgatcgatga
    10861 gtcacttgac cccattgaag gcattgcacg caaatacctg aacactccgt gttctgtcat
    10921 gtccaacaac caggaccgac tggacaaact cagcgagctc attgaacgct tcaaggcaga
    10981 cggcgttgtc gatgtggttc tccaggcctg ccacacctat aacatagaag gcttctccgt
    11041 gaagcgtcac gtcaaggaaa agcacaacct cccatacatc gcccttgaga ccgactatgc
    11101 ctcctcagac acaggccagt taaaaactcg ccttggcgct tttattgaga tgctctaatt
    11161 cggcaaacca ctcaaacaaa aatcaaaaaa tgaaaccacg acacatcccg gaaaggaaat
    11221 gacctcatga tccacatggg catagatatt gggtcggtgt gcgctaaggg cgccgccatc
    11281 cgtgatggac gcatggaaaa agttatgctg ccaacagggt ggaacatcaa agagaccgcg
    11341 tcccttctca agatggctct gcttgaaaaa atggatgcag aagacagcgc agttcgcggc
    11401 gtcgttgcca caggctatgg ccgcgtatcc atcccttacg cggacaagaa agtcaccgag
    11461 atcacctgcc atgccagggg cgccgtccac ctgaatccag cgactcgcac cattattgac
    11521 ataggcggac aagacagcaa actgatctcc atagatgccg atggtcgcgt ccaagacttt
    11581 gtcatgaacg acaaatgcgc tgccggcacc ggtcgatttc tccaggtcat ggcccacgtg
    11641 cttgaaatag aagtcgacga cctcgaccaa cttgccacac aaggagaccc tgtcaccatc
    11701 aacgccatgt gcaccgtctt cgctgagagt gaaatcatta gcttactggc ccaaggcaca
    11761 gaaaaaggcg cgattgccgc cggtatcctc agttccattt cccagcgcgt ccagcatctg
    11821 tccagccgca tttctgttca ggaccagctt ctcttcacag gcggcgtatc aaactcaggc
    11881 tacctaagac agctgctcac cagcaaactt aattttgaag tccaccatca ccccgacgcg
    11941 caatttgccg gtgccatagg tgcggccttg cttgcgcagg aatcataagg gacggttcct
    12001 tctgttcctt ccaatcaaaa gggaaatcca atcgagtagg aggctaccca ttagttgagt
    12061 agccgtcctc tcacaccacc gtacgtaccg ttcggtatac ggcggttcaa ccgcttgagt
    12121 gcattaagcg taattgctcg tactgagccg ggaagtcata atacccggcc agtgcgagct
    12181 tttcatttgt aatggaacga ttgagtacag cacttccggc aattcgccag tatcccagac
    12241 gggtattgcc ccactggtat gcctgccact ccggaatacc cagtttcttt agattcatga
    12301 tcctggttct tggcttcttc cattgtttcc agacgtacat ccgaagcctc cgtctcaacc
    12361 actcgttcca actcatcagc gtccgcttta tgtcggctac atagtaataa ccgagccatc
    12421 cacggatgaa gcttttaacg ttttccatga ccatgcgcac atttctgccc tgatttcggc
    12481 gggtcagttg cctcagtttc cgttttgcct tcgccaggga ttcccgatgg gcgcgtatat
    12541 agacgccttt cttgttcttc ccaaggcaaa agccaagaaa tttgaagtgt tttattgcca
    12601 acacactgac gaccttgctc ttttgggcat tcattttcag tttcagtttg ccctccagat
    12661 acct
//
