LOCUS       NC_021016.1            22113 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_021016.1 Anaerostipes hadrus, complete sequence.
ACCESSION   NC_021016
VERSION     NC_021016.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:34:32
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 952724
            Orig. end    :: 974837
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1080
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_941"
                     /sec_met_domain="GATase (E-value: 7.4e-46, bitscore: 153.8,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNAFLILEDGHVFEGKSFGAQKEVICEVVFNTSMTGYLEVLTDPS
                     YQGQGVVMTYPLIGNYGVCLEDIESEKPWHSAFIVREISRTSSNFRREEDLEDYLKEHD
                     IPGICGVDTRAITKILREHGCMGGMITTNPDFNLDEILPKLKEYTVTDAVKTVSRTEKE
                     HFDGDGFKVALLDLGTKNNIIRSLEKRGCDVTVYPADTTAEEILGDQPDGIMLSNGPGD
                     PKECVQIIKEIKKLYDSEVPIFAICLGHQLMALATGADTEKMRWGHRGGNHPVKDLKSG
                     RVYISSQNHGYVIKEETIDPDVAEVSFINVNDKTIEGLDYKNKNIRTVQFHPEACPGPQ
                     DTAYLFDEFMDRMKGAKNA"
     protocluster    1..22113
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[962660:965688]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      9937..12964
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..22113
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..22113
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Pyruvate2acetate-formate"
                     /region_number="5"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             1073..4273
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CPSase_L_D2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1060:ATP-grasp domain (Score: 41.6; E-value: 4.5e-13)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_942"
                     /sec_met_domain="CPSase_L_D2 (E-value: 2.6e-79, bitscore:
                     263.1, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKREDIKKVLVIGSGPIVIGQAAEFDYAGTQACRALQEEGVEVV
                     LVNSNPATIMTDKDIADKVYIEPLTASVIEKIIEKEKPDSILPTLGGQAALNLAMELVE
                     SGYLEKSGVKLIGTSPSTIKKAEDRLEFQQTMEKIGEPIAAGQVVKTVEDGVEFAKVIG
                     YPAVLRPAYTLGGSGGGIAHNQEELETILENGLRLSRVGEVLVERYIGGWKEVEYEVMR
                     DENGTCITICNMENIDPVGVHTGDSIVVAPSQTLGDKEYQMLRTSALNIITELDVHGGC
                     NVQYALNPDSFEYCVIEVNPRVSRSSALASKATGYPIAKVTAKIAIGYTLDEIENAVTK
                     KTYASFEPMLDYCVVKMPRLPFDKFIHAKRTLTTQMKATGEVMSIGTNFEGALMKAIRS
                     LEQHVDSLIFGDYDKLTDDELLKELEKIDDLRIYVIAEAIRRGFDYDTIFNITKIDRWF
                     LDKIAVLVEMEKKLAKADTLDKELLQEAKRLEFPDKVIGSLTGKTEREIKELRNEYNIH
                     AAYKMVDTCAAEFDAATPYYYSCYDGENEVKETSEKKKVMVLGSGPIRIGQGIEFDFCS
                     VHSVWALSKEGYETIIVNNNPETVSTDFDVADKLYFEPLTAEDVESIVDLEKPDGAVVQ
                     FGGQTAIKLTEALMKMGVPILGTSAENVDAAEDRELFDEILEECCIPRPKGTTVFTCEE
                     ALEVAHKLGYPVLVRPSYVLGGQGMQIAVSDEDITAFMEVINRYEQEHPILIDKYLVGK
                     EVEVDAVCDGTDILIPGIMEHVERAGIHSGDSISVYPSINLTDRIKRIIAEYTRKLAKS
                     LHVIGLINIQFIVADDEVYVIEVNPRSSRTVPYISKVTGIPIVALAAKVITGAKIRDLG
                     YEPGLQKESEYYAVKKPVFSFEKLRGAEISLGPEMKSTGECLGISKNFHEALYKAFLGA
                     GVNLPKYKKMILTVKDSDKIDAIDIGRRFEALGYEIFSTKSTCRVLNEAGVHAKQINKL
                     EEESPNLLDLILDDKIDLVIDTPSQGVGRSRDGFLIRRYAIETGVTCLTSLDTADALLT
                     SLETGNRDQLSVVDIAQI"
     CDS             4292..5623
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gln-synt_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_943"
                     /sec_met_domain="Gln-synt_C (E-value: 8.3e-132, bitscore:
                     436.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRYTKQDVIDLVRENDVEFIRLQFSDLFGTMKNVAITARQLEKA
                     LDNKCTFDGSSVDGFVRIEESDMYLYPDLDSFAIFPWNAGGNRVARLICDVYGQDGLPF
                     AGDPRNVLKRVMVECQKMGYKFNVGPECEFFLFHTDEEGRPTTVSHEKAGYFDVAPLDL
                     GESARRDMILNLEDMGFEIEASHHEVAPAQHEIDFKYDNALRTADNILTFKFIVKYIAK
                     RHGLYASFMPKPITGVDGSGMHLNMSLWKNGKNIFADSKNDLGISEEAFHFMAGVMEHA
                     NEMCLITNPLVNSYKRIVPGYEAPVDVSWSPSNRSPLIRVPAARGSGTRLEFRSPDSAA
                     NPYLALAVSLAAGLDGIKRKLTPGKGSMKNQYEMAEGEKQEAGINTLPRDMKEALEIFK
                     QSTYMKELLGDHIFNKYVEAKSAEWESYQKFVSQWEVDRYLYKI"
     CDS             5659..6213
                     /locus_tag="ctg1_944"
                     /transl_table=11
                     /translation="LVNVIVLFPKQEVARSIRNLLVRSGFEVTAVCATGAQVVQRMEGV
                     EEGLVVCGYKCSDMIYSELREYLSEEVKMLLIASRQYLDDCVYPNVIGLSMPLKGYELV
                     EKTREIVTEISEKQRRRKQRPKQRTREEVRLLEEVKELLMQNNQITESEAHAYIQQRSM
                     NSGVGLIEMAKMIKESLTYQN"
     CDS             6223..7437
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_945"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4.7e-32, bitscore:
                     109.0, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKINDNYLKLPGSYLFSTIAKKVNAYSEANPDKNIIRLGIGDVT
                     QPLAPAIIDSLHKAVDEMGHAETFHGYAPDLGYEFLRNAIAKNDYQDRGADIKADEIFV
                     SDGAKCDSGNIQEIFAQDNKIAVCDPVYPVYVDTNVMAGRAGTYDKATETWSDVIYMPC
                     TAENNFAPDFPSEVPDIIYLCFPNNPTGSTITKDQLQGWVDYANKNGCVIIYDAAYEAY
                     ISEDNVAHTIYECEGARTCAIELKSFSKNAGFTGVRLGYTVIPKDLKCGDTQLHALWAR
                     RHGTKYNGAPYIVQRAGEAVYSEAGKAQLKEQVGYYMNNAKVIFNGLQDAGYTVSGGVN
                     APYIWLKTPDNMTSWEFFDHLLEDANVVGTPGSGFGPSGEGYFRLTAFGNYENTVEAIE
                     RIKRM"
     CDS             7759..8472
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IMP_cyclohyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_946"
                     /sec_met_domain="IMP_cyclohyd (E-value: 1.1e-69, bitscore:
                     231.4, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLALAQELKENAYPGRGIVIGRSKDGKKAVTAYFIMGRSENSR
                     NRVFVEEGEGIRTQAFDPAKLEDPSLIIYAPVRVLGDETIVTNGDQTDTVYEGREKGLT
                     FEESLRSREFEPDGPNYTPRISGLMKIKDGTFHYAMSILKSNNGNPESCNRFTYTYENP
                     IAGEGRFIHTYMHNGNPLPSFEGEPKLVAIEEDIDDFTNTLWNSLNDDNKVSLFVRYID
                     IATGEYETRIVNKNK"
     CDS             8505..9683
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AICARFT_IMPCHas"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_947"
                     /sec_met_domain="AICARFT_IMPCHas (E-value: 1.1e-61,
                     bitscore: 206.3, seeds: 747, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKELELKYGCNPNQKPSRIYMADGSELPIEVLNGRPGYINFLDAF
                     NGWQLVRELKKATGLPAATSFKHVSPAGASVGRPMSDTLKKIYWVDDMGDLSPLACAYA
                     RARGADRMSSFGDFISLSDVCDADTARLIKREVSDGVIAPGYTDEALEILKAKKNGNYN
                     IIKIDENYTPAPLEHKQVFGVTFEQGRQELPIDDELLSNIVTENKEIPEEALIDMKISL
                     IVLKYTQSNSVCFVKDGQAIGIGAGQQSRVHCTRLAGQKADNWWLRQCPKVMNLPFKEK
                     IRRADRDNAIDLYIGDEYMDVLADGAWENIFTEKPEVFTKEEKREWLDKLTDVTLGSDA
                     FFPFFDNIERAHKSGVKYIAQPGGSVRDDAVIDCCNKYNMAMAFTGIRLFHH"
     CDS             9937..12189
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_948"
                     /sec_met_domain="Gly_radical (E-value: 4.4e-40, bitscore:
                     134.0, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 8.5e-266, bitscore:
                     880.6, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQFEEWEGFKGRIWKEEINTRDFIQENYTPYDGDESFLAGSTEA
                     TDKLWGILQGLQKEERKKGGVLDMDTDIVSSLTSHGPGYISEETKDLEQIVGLQTDKPL
                     KRAFMPYGGIKMAEESCRNYGYEPSERLHEIFTKYSKTHNTAVFDAYTPEMKKARHNKI
                     ITGLPDTYGRGRIVGDYRRVALYGIDYLLEEKENDFANCGCGVMTDDVIRLREEIAEQK
                     KALKGMKEMAKIYGFDISRPAKTAKEAIQWMYFGYLAAIKTQNGAAMSIGRVATFLDIY
                     IQRDLDKGIITEEEAQEMIDHLTMKFRMVKFARIPSYNQLFSGDPVWATLDLAGIGVDG
                     RSMVTKTDFRFLHTLENMGPSPEPNITVLYSSDLPENFKKYAADISIRTSSIQYENDDV
                     MKPVWGDDYAICCCVSATKTGKEMQFFGARANLAKCLLYAINGGVDCKSKQQVGPSYKP
                     ITAEYLDYDEVMEKYDVMMDWLVDLYVNTLNLIQYMHDKYYYEAAELALMDTELERTFA
                     TGIAGFSHAVDSLSAIKYAKVKAIRDEDGLVVDYEIEGDFPKYGNDDDRADDIAVWLLR
                     TFLAKIKKHHTYRNSEPTTSILTITSNVVYGKATGTMPDGRKAGEPLAPGANPSYGAEQ
                     NGLLASLNSVAKLPYEWALDGISNTQTINPDALGHEEGERINNLVNVMDGYFDQGAHHL
                     NVNVFGKEKLIDAMEHPEKEEYANFTIRVSGYAVKFIDLTREQQMDVISRTCHATM"
     CDS             12212..12964
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 78.2;
                     E-value: 2.4e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_949"
                     /sec_met_domain="Radical_SAM (E-value: 1.6e-26, bitscore:
                     91.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEKITGKIHSIETFGLVDGPGVRFIAFMQGCRMRCKYCHNPETW
                     QENCGEDWQAEALLKRALRYRMYWGSDGGITVSGGEPLLQIEFLIEFFKLAKQEGIHTA
                     LDTSANPYTKEEPFHSKWLELMKYTDLVILDLKEMDEEKHKKLTGCPNSNILAMAQEIS
                     DLGVDLWIRHVLVPDLTDDEKGLADLKHFIDGLKTVKRVEILPYHTLGLFKWEKLGIKY
                     PLEGVNPPSEEAVARAEKILGIEKVSQK"
     CDS             13287..13661
                     /locus_tag="ctg1_950"
                     /transl_table=11
                     /translation="MKLIELSEVEILIMKSIWKLGDGITVYEIIDYLDQVYDRKYTRST
                     VKTYITKLKKKGFVDTQVKGNYSYITAKITEEMYREEQMELMKDFWHDGSMKELVQTLT
                     HTISKEEKEELKDLINDLDD"
     CDS             13645..15045
                     /locus_tag="ctg1_951"
                     /transl_table=11
                     /translation="MIWMIKKIYIYVISMILLNGLVGSISYLCFRKIRQQLERKGLISM
                     CITVLRGAVLSFLMPIVIVLIYFIYYVYEEDYTMFALSPLVGWVFFVVGIIWTIGFLKA
                     IVKTIRIQTQMNQLRKRACVCSKSILDCKNQWKEEVGVRRNVEIKTVYGLAVPIICGFL
                     KPMILLPEREYNKEELKIICIHELIHCKHKDILWKQLCGLVRVIHWWNPLVKQLDMDVD
                     SWNETYCDLESTTIMKSKKRYFTTICEIGISPFAKGAYLCAALGEDKSQLKTRILRIKS
                     IENKNTRNVMAGTFLCIGLSFVVVAVIILSTIGYHKIYVETVWATEIEEDLPEEETEYT
                     MDLKEYTAKRIGTNLAVTKLKQNIKKGEEIDVVQPLNAKTRLETKELELKKGEKIDLTV
                     FSSQEIQREDKDFVAGIIDGTGKERYVMHAVDIIHDFYVKKDGKYKVFVENRYKKKIKI
                     GIAICVEK"
     CDS             15049..16173
                     /locus_tag="ctg1_952"
                     /transl_table=11
                     /translation="MRKYVVRFMVFYILSIGCLLGIIIYSYQNKIDRHNEQVEIEYPGV
                     WKLSDEYDNRNSSYMEFLHQKNSLSILKKVYKELEKAELYREYSRQILSYHEYFRGNEK
                     LASGSYNDKTEDGYLTNLTVLQMPEKMISEKKIEQHIEKGRCFTLKEYQRPLNQEIPLI
                     AGYDYQKVFHLNQKIKAGYLGTENCTFKIVGFLHKNTRLSSELNLDETLIMPTVSKMKT
                     MKQENEKILMSVKCSGYFCYKNEKEYRQISNLLKRIRRETGYRYVIPQMKWKSNNLLPM
                     TTEKALIFMSLNLLLEFIVVYKVLAVNTRKVKTLVYKTVALCTSGSIFANVFLRFLFPK
                     HIKIIQIYSSDFVAYMIIVFLLCAGMIGLKEKRT"
     CDS             16170..17069
                     /locus_tag="ctg1_953"
                     /transl_table=11
                     /translation="MMEKILLGSSYLAQAIVMATIAFAVISTIYYLRYNKKIICQPGWI
                     IKYIFLVYIATVGMVTRVLDITSWSYGGFTAWNIVPFVNESWKLMLLNTLMFLPMGLFV
                     PIFIKKIKWNYGKAIIVGTLISLMIEFVQVVFAGRIGDIDDIIFNTLGFLIGYILENLL
                     QKILLKKQLGFGTEALVLVMINGFLSIPFYEKTVSIGDMILDSLNLNSWSGNSGYILSY
                     NGIHYTMIPCIILAVISWAIAHRYPKDYGAKTAKIISIFMIVCFIGNFIQILSQDSIIP
                     MLAASIVCAVISRKTIRY"
     CDS             17132..17392
                     /locus_tag="ctg1_954"
                     /transl_table=11
                     /translation="MKKLSILLAGVCLTAALYGAGTIYGQNKTNTAKQSEDKVTTNKYQ
                     GVTIKDKAKGKVTKQQVKQLKKEHSGKDEGNIIIWEAEEAE"
     CDS             17406..17516
                     /locus_tag="ctg1_955"
                     /transl_table=11
                     /translation="MLIPDLIIQLITVVIGVALYAAIFKIVKNVIHKIIY"
     CDS             complement(17880..18971)
                     /locus_tag="ctg1_956"
                     /transl_table=11
                     /translation="MKLGIVGLPNVGKSTLFNSLTKAGAESANYPFCTIDPNVGIVTVP
                     DARVDYLAEKYHSKKVIPAAIEFVDIAGLVKGASKGEGLGNQFLANIREVDAIVHVVRC
                     FDDGNIVHVDGSVNPLRDIETINFELIFSDIEVLDRRIAKSTKGSRNDKSLAHEVEFLS
                     KVKAHLEDGKLAKTFEVDDEEDQEILNSCNLLTIKPVIFAANVNEDELAGEDNDYVKAV
                     REYAADVDAKVFVVCAQIEQEISELDDDEKKEFLEDLGLEESGLEKLISASYSLLGLIS
                     FLTSGEDETRAWTIKEGTKAPQAAGKIHTDFERGFICAEVVSFEDLKEYGTMQACKEKG
                     LVRQEGKEYVVKDGDIIVFRFNV"
     CDS             19157..20044
                     /locus_tag="ctg1_957"
                     /transl_table=11
                     /translation="MEHQIRFPHLGIVLKNVGDGINIGGFEIKYYGMIIATGFLLGLIV
                     SYYAAKHENKFDPELVFDYLITMIIPAIVGARLYYVIFSWDYYKNHLSEIIQIRNGGLA
                     IYGGVIAGAITLYIFCKKKHLSMLQFGDVAVKGLLVGQILGRWGNFFNREAFGSYTNSL
                     FAMQIPTNFFIEHGRIDEIVSNGLYDKATYVVSGNEAATFIQVHPTFLYESMWNLVLLL
                     LIIFFFTKRKKFDGELIAIYCIGYGIGRFLIEGLRTDSLMIGSTGIRVSQILALILAVF
                     GTAFIMYKRKKITK"
     CDS             20218..20655
                     /locus_tag="ctg1_958"
                     /transl_table=11
                     /translation="MSMFMGEFNHTIDAKGRLIIPSRFREELGQEFVMTKGLDGCLFVF
                     PQNEWESFQGKLKTLPLINKDARKFSRFFMAGAAPCEMDKQGRTLIPATLREFAQMKKE
                     VVLTGMADHIEIWSKEKWIENNSYEDMDDIAASMQELGLSI"
     CDS             20668..21606
                     /locus_tag="ctg1_959"
                     /transl_table=11
                     /translation="MEFKHISVLLDETIEELHIKPDGIYVDGTLGGGGHAYHVCQKLSE
                     KGRYIGIDQDADAIAASTKRLEPFKDKVTIVRDNYVNMPKVLHDLGIEHVDGILLDLGV
                     SSFQLDEKERGFTYREDVPLDMRMDQRQSLTARDIVNEYSEMELFHIIRDYGEEKFAKN
                     IAKHIVNKRKESPIETTGQLIEVIKGAIPMKVRAVGGHPAKKTFQAIRIECNRELDVLK
                     DSIDAMIDLLNPGGRLCIITFHSLEDRIVKRAFKKNENPCTCPPNFPVCVCGNVSKGKQ
                     LTRKPIIPGEEELEYNKRAKSSKLRVFERAE"
     CDS             21619..22113
                     /locus_tag="ctg1_960"
                     /transl_table=11
                     /translation="MDKTRQERYNMIYGNTARKIEDLAAEPVRRQPRKTRKARPRREHQ
                     VKESTRQNQKRAMSIDLAFIKVLVAGLCVIAVASFFYLSERTKVLNQKAALTDAKTQLN
                     TLQVENEDLNLEIEQSIRFDTVETAAKKYGMVKPDSKHTLRYESQDAEYIRQYGKIPKA
                     D"
ORIGIN
        1 atgaacgcat ttttgatatt ggaagacgga cacgtatttg agggaaaaag ttttggagcc
       61 caaaaagaag tgatctgtga agtcgtattt aatacttcca tgacaggtta tttagaagta
      121 ttaacagacc cttcctatca gggacaggga gtcgtaatga cttacccact gattggaaat
      181 tatggagtat gtctagagga catcgaatct gaaaaacctt ggcactcagc ctttatcgta
      241 agagaaatct caagaacttc aagcaacttc agaagagaag aagacttaga agattatctg
      301 aaagaacatg acattccagg tatttgtggt gttgacacaa gagctatcac aaagatctta
      361 agagaacatg gatgcatggg tggaatgatc accacaaatc ctgatttcaa tttagatgaa
      421 atccttccaa aattaaaaga atatacagta acagatgcag taaaaactgt ttccagaaca
      481 gaaaaagaac atttcgatgg agatggattt aaagttgcat tattagacct tggaacaaag
      541 aataatatta ttcgttcttt agaaaaacgt ggatgtgatg taacagttta tccagcagat
      601 acaacagcag aagaaatctt aggagatcag ccagacggta tcatgttatc aaacggacct
      661 ggagatccaa aagaatgtgt acagatcatc aaagagatca agaaattata tgacagcgag
      721 gtacctatct ttgcaatctg tttaggacat cagttgatgg cacttgcaac aggtgcagac
      781 acagaaaaaa tgcgttgggg acatcgtgga ggaaatcatc cggtgaaaga cttaaagagc
      841 ggaagagttt atatttcttc tcagaaccac ggatatgtga tcaaggaaga aacaattgat
      901 ccagatgttg cagaagtttc ctttattaat gtaaatgata aaacaatcga aggattagac
      961 tataaaaata aaaacattcg aacagttcag ttccatccag aagcatgccc tggaccacag
     1021 gatacagctt acttatttga tgaatttatg gatagaatga aaggagcaaa aaatgcctaa
     1081 gagagaagat ataaagaaag tacttgtaat cggatcagga ccgatcgtta ttggacaggc
     1141 agcagaattt gactatgcag gaacacaggc ttgtagagca cttcaggaag agggagtgga
     1201 agtagtctta gtaaactcaa accctgcaac gatcatgaca gataaagaca ttgcagataa
     1261 agtatatatc gagccattaa cagcttctgt catcgaaaag atcattgaaa aagaaaaacc
     1321 agacagcatc cttccaacac ttggtggaca ggcagcctta aatctggcca tggaactagt
     1381 agagagcgga taccttgaaa aatccggagt gaaattgatc ggtacatctc catctacgat
     1441 caaaaaagca gaagaccgtt tagaattcca gcagacaatg gaaaagatcg gggaaccgat
     1501 cgccgcagga caggttgtta aaacagtaga agatggtgtg gaattcgcta aagtgatcgg
     1561 atatccagca gtacttcgtc cagcatatac acttggagga agtggtggag gaatcgccca
     1621 taaccaggaa gaattagaga cgatccttga gaatggtctt cgtctaagtc gtgtaggtga
     1681 agtattagta gaacgttaca tcggtggatg gaaggaagtc gaatacgaag taatgcgtga
     1741 tgaaaatgga acatgtatta caatctgtaa catggaaaac atcgacccag ttggtgttca
     1801 tacaggagac agtatcgtag tagctccatc tcagacttta ggagataaag aataccagat
     1861 gcttcgtaca tctgcattaa acatcatcac agaattagat gttcatggtg gatgtaacgt
     1921 acagtacgca ttgaatccag acagctttga atactgcgtt attgaggtaa accctcgtgt
     1981 cagccgttct tcagccttag cttccaaagc aacaggatac ccaattgcga aagtaacagc
     2041 aaagatcgca atcggatata cattagatga gattgaaaat gcagtaacga agaaaacata
     2101 tgcaagtttt gagccaatgc ttgattactg tgttgttaaa atgcctagac ttccattcga
     2161 taagtttatt catgcaaaac gtactctgac aactcagatg aaagcaactg gagaagttat
     2221 gagtatcgga acaaacttcg aaggggcatt aatgaaagcg atccgttcct tagagcagca
     2281 tgtggacagt ttgatcttcg gtgattacga taaattaaca gacgatgagt tattaaaaga
     2341 acttgaaaag atcgatgatc ttcgtatcta tgtgatcgca gaagcgatcc gtcgtggatt
     2401 tgattacgat acgatcttta atattacaaa gatcgaccgt tggttcttag ataagattgc
     2461 agttttagtt gagatggaaa agaaattagc caaagctgat acattagaca aagaattatt
     2521 acaggaagca aaacgcttag aattcccaga caaggtgatc ggaagcttaa caggtaagac
     2581 agagcgtgag atcaaagaat taagaaatga atataatatc catgcagcat ataagatggt
     2641 agatacatgt gcagccgagt ttgatgcagc aacaccttac tactattctt gctatgatgg
     2701 tgagaacgaa gtgaaagaaa catccgaaaa gaaaaaagtc atggtacttg gttctggacc
     2761 gatccgtatc ggtcagggta tcgaatttga cttctgttct gtacacagcg tatgggcatt
     2821 aagtaaagaa ggatacgaga cgatcatcgt aaacaacaac cctgaaacag tttctacaga
     2881 ctttgacgtt gctgataaac tttacttcga gccattaaca gcagaagatg tagaaagtat
     2941 cgtagatctt gaaaaaccag atggtgcggt tgtacagttt ggtggacaga cagcgatcaa
     3001 attaacagaa gcactgatga agatgggagt accaatcctt ggaacaagtg ctgaaaatgt
     3061 cgatgcagcc gaagacagag aattattcga tgagatcttg gaagaatgct gtattccaag
     3121 accaaaagga acaacagtat ttacatgtga agaagcatta gaagttgctc ataaacttgg
     3181 atatccagtt cttgtaagac cttcttatgt acttggtgga cagggaatgc agattgctgt
     3241 atctgatgaa gatatcacgg cattcatgga agttatcaac cgttacgaac aggaacatcc
     3301 aattctgatc gataaatatc tggttggtaa agaagtcgaa gtcgatgctg tttgtgatgg
     3361 aacagatatc ctgatcccag gaatcatgga acatgtggaa cgtgctggaa tccattcagg
     3421 agacagtatt tccgtatatc catctatcaa tttaacagat agaattaaga gaatcattgc
     3481 agaatataca agaaaacttg caaaatcatt acatgttatc ggactgatca acattcagtt
     3541 tatcgtagca gatgatgaag tatatgttat cgaagtaaac ccaagatcca gccgtacagt
     3601 gccttacatc agtaaagtta caggtattcc gatcgtagcg ttagcagcga aagtgatcac
     3661 tggagctaag atcagagatc ttggatatga accaggactt cagaaagaat ctgaatacta
     3721 tgcagtgaag aaaccagtat tctcttttga aaaattaaga ggagcagaga tcagccttgg
     3781 gcctgaaatg aaatctacag gtgaatgtct tggaatttct aagaacttcc atgaagcgtt
     3841 atataaagca ttcttaggag ctggagtaaa tcttccaaaa tacaagaaga tgatcttaac
     3901 agtgaaagac tccgataaga tcgatgcgat tgatattgga cgcagatttg aagcattagg
     3961 atatgagatt ttctcaacaa agagcacttg cagagtctta aatgaagctg gagttcatgc
     4021 aaaacagatt aataaattag aagaagaatc tccaaacttg ctagatctca ttttagatga
     4081 taaaattgat ttagtcattg atacaccatc tcagggtgta ggtcgaagca gagatggatt
     4141 cctgatccgc cgttacgcga ttgaaacagg agtaacatgc cttacaagtc ttgatacggc
     4201 agatgctcta ctgactagtt tggaaacagg aaacagagat cagctcagcg tagttgatat
     4261 cgcacagatt taattaagaa ggagtgatgt tatgggtcga tacacaaaac aggatgtgat
     4321 agacctcgtc agagaaaatg atgtcgaatt tatcagacta caattttctg acttgttcgg
     4381 aacaatgaag aacgtcgcga tcaccgcaag acagcttgag aaagcgttgg ataataagtg
     4441 tacatttgat ggatctagtg tagatggatt tgtccgtatt gaagaatcag atatgtattt
     4501 atatccagat cttgacagct ttgcaatctt cccgtggaat gcgggaggaa accgcgtggc
     4561 aagattgatc tgtgatgtat acggacaaga tggacttcca tttgctggag atccaagaaa
     4621 tgtattaaaa cgagtgatgg ttgagtgcca gaaaatgggt tataaattta acgtcggtcc
     4681 ggaatgtgaa tttttcttat tccacacaga tgaagaaggc cgcccaacga cggtttctca
     4741 tgagaaagcc ggatattttg atgtagctcc gttagattta ggagaaagtg ccagaagaga
     4801 tatgatcttg aatcttgaag atatgggatt tgagatcgag gcatctcatc atgaagttgc
     4861 accagcacag catgagatcg actttaagta tgacaatgcc ttaagaacgg ccgataacat
     4921 cctcacattt aaattcatcg taaaatatat tgctaaaaga catggacttt atgcaagttt
     4981 tatgccaaaa ccgatcactg gagtggacgg ttcaggaatg catcttaaca tgtctttatg
     5041 gaagaatgga aagaatattt tcgctgattc taagaatgat cttggaatca gtgaggaggc
     5101 ttttcacttc atggctggag ttatggaaca tgcaaatgag atgtgcctga tcacaaatcc
     5161 actggtaaac tcttataaga gaatcgtgcc aggatatgag gcacctgtgg atgtttcatg
     5221 gtcaccatcg aatagaagtc cacttatcag agtaccagca gcccgtggaa gcggaacaag
     5281 gcttgaattt agaagccctg attctgctgc gaatccttac cttgcactgg cagtcagcct
     5341 tgcagcagga ttagatggga tcaagcgcaa attaacacca ggaaaaggtt ccatgaagaa
     5401 tcagtatgag atggctgagg gagaaaaaca agaagcaggg attaatacac tgccaagaga
     5461 catgaaagaa gctcttgaga ttttcaaaca aagcacttat atgaaagaac ttttaggaga
     5521 tcatattttt aacaagtatg ttgaagctaa gagtgctgaa tgggagtctt atcagaagtt
     5581 cgtatcacaa tgggaagtcg atcgttattt atacaagatc taatgattga tatatacatg
     5641 atacgggagg tgagaagctt ggtaaacgtc atcgttttat tcccgaaaca agaagtcgcc
     5701 agaagcatta ggaatcttct ggtaagaagt ggttttgaag tgaccgctgt atgtgcaacg
     5761 ggtgcacagg tagtccaacg tatggaaggt gttgaagaag gactagtcgt ctgcggatac
     5821 aaatgttccg atatgatcta cagtgaatta agagaatatc tttctgaaga ggtcaagatg
     5881 ttgctgatcg cttctcgcca atatttagat gactgcgtgt atccgaatgt cataggactt
     5941 tcgatgccgt taaaagggta tgaattagtc gagaaaacga gagagatcgt taccgaaatt
     6001 tctgagaagc aaagacgaag aaaacaacgt ccaaaacaac gtacgagaga agaagtccgt
     6061 cttctggaag aagtcaaaga attactgatg cagaataatc agattacaga gagtgaagcc
     6121 cacgcatata tacaacagag aagcatgaac agtggagtgg gtcttatcga aatggcaaag
     6181 atgattaaag aatcattaac atatcaaaac taggaggaat ttatgtttaa aattaacgac
     6241 aactacttga aactgcctgg aagttattta ttttctacaa ttgcgaaaaa agtaaatgca
     6301 tattccgagg caaaccctga caaaaatatt attcgtttag gaattggaga cgtaacacag
     6361 cctctggcac cagcgatcat tgactcttta cacaaagcag tagatgaaat gggacatgca
     6421 gaaacatttc acggatacgc accagacctt ggatatgaat ttttaagaaa tgcaatcgca
     6481 aagaatgatt atcaggatcg tggagcagat atcaaagcag atgaaatctt tgtaagtgat
     6541 ggagcaaaat gtgattctgg aaatattcag gaaatctttg cacaggataa caagattgcc
     6601 gtatgtgatc ctgtataccc agtatatgta gatacaaacg ttatggcagg aagagccgga
     6661 acatatgata aagcaacaga aacatggagc gatgttatct acatgccatg tacagcagag
     6721 aataacttcg caccagattt cccaagcgaa gtgccagata tcatttacct ttgcttccct
     6781 aacaatccaa ctggatcaac aatcacaaaa gaccagttac agggatgggt agactatgca
     6841 aacaaaaacg gatgcgtgat catttatgat gcagcatacg aagcatatat ctcagaagat
     6901 aacgttgcac atacaattta tgaatgtgaa ggtgcaagaa catgtgcgat cgaattaaag
     6961 agtttctcta agaatgcagg atttacagga gttcgtttag gatatactgt tatccctaaa
     7021 gatttaaaat gtggagatac acagttacat gcgttatggg caagacgtca cggaacaaaa
     7081 tataacggag ctccatacat cgtacagaga gctggagaag cagtttactc tgaagccgga
     7141 aaagctcagt taaaagaaca ggttggatac tacatgaaca atgcaaaagt aatctttaac
     7201 ggattacagg atgcaggata cacagtatct ggtggtgtta atgcgccata catctggtta
     7261 aagacaccag ataacatgac atcttgggaa ttcttcgatc atctgttaga agatgccaac
     7321 gtcgttggaa caccaggatc aggattcgga ccaagcggag aaggatactt ccgacttaca
     7381 gcgttcggta actatgagaa tacagtcgaa gctattgaac gaatcaagag aatgtaattt
     7441 ttgaatataa aataagaaaa aggatggaat gtcagggatt gatgttccat tcttttttgt
     7501 atgttaaaat aataaattat gcggaatttc tacctgtttt tttagacgaa aactaaaaaa
     7561 taagatataa tacattgtaa aataaaaaag cataactatg taaaaaatga tagaaataaa
     7621 ggacagtgtt acaaaaatat ataggaaacc tgccctttat tttataattg ttagtttttt
     7681 cttgtattca atccattttt tatatacaat agaagaaata aaaaaacaag attttcaaaa
     7741 gaaggagatt taagaccaat gaagaagtta gctcttgctc aggaattaaa ggaaaatgct
     7801 tacccaggac gaggaatcgt catcggaaga tccaaagatg ggaagaaagc ggtcactgca
     7861 tactttatca tgggacgcag tgagaatagt cgtaatcgtg tctttgtaga agaaggggaa
     7921 ggaatccgca cacaggcatt tgatcctgcc aaactagaag atccaagcct gatcatttat
     7981 gcaccagttc gtgttcttgg agacgagacg atcgttacga acggggatca gacagacaca
     8041 gtatatgaag gaagagaaaa gggacttacc tttgaagaat ctttaagaag tcgtgagttt
     8101 gaaccagacg gaccaaacta tacaccaaga atttctggtc tgatgaagat taaagatggg
     8161 acatttcact atgcaatgtc tattttaaag agtaacaatg gaaatccaga aagttgcaat
     8221 cgatttacat atacatatga aaatccaatc gcaggagaag gacgttttat ccacacatat
     8281 atgcataatg ggaatccact tccaagtttt gaaggagaac ctaaattagt agcgatcgaa
     8341 gaagatatcg atgacttcac aaatacactt tggaacagct taaacgatga caacaaagta
     8401 tctctgtttg tacgttatat tgatattgca acaggagaat atgagacaag aatcgtaaat
     8461 aagaacaaat aatcagtcga tcagcagatc aaaggagaag aaaaatgaag gaattagaat
     8521 taaagtacgg atgtaatcca aaccagaaac catcaagaat ctacatggca gatggaagtg
     8581 aacttccaat tgaagtatta aacggaagac cagggtacat caactttttg gatgcattta
     8641 atggatggca gctggtaaga gaattaaaga aagcaacagg acttcctgct gcaacttctt
     8701 tcaaacacgt atcacctgcg ggagcatctg taggacgtcc aatgtctgat accttaaaga
     8761 agatctactg ggtagatgat atgggagatt tatctccatt agcatgtgca tatgccagag
     8821 caagaggtgc agaccgtatg tcttcattcg gtgactttat ttctttatct gatgtatgtg
     8881 atgcagatac agcacgtctg atcaagagag aagtatctga cggagtgatc gcaccaggat
     8941 acacagatga agcactggaa atcttaaaag caaagaaaaa cggaaactat aacatcatca
     9001 agatcgatga gaactataca ccagcaccat tagagcataa acaggtattt ggtgttacat
     9061 ttgaacaggg aagacaggaa cttccgatcg atgatgaatt attatctaat atcgtgactg
     9121 agaacaaaga gattccagaa gaagcattga tcgatatgaa gatttctttg atcgtattaa
     9181 aatacacaca gtctaactct gtatgtttcg taaaagacgg acaggcgatc ggaatcggag
     9241 cagggcagca gtcacgtgtg cattgtacaa gacttgcagg acagaaggca gacaactggt
     9301 ggttaagaca gtgtccaaaa gttatgaacc tgccatttaa agaaaaaatc cgccgtgcag
     9361 acagagataa tgcgatcgat ctttacattg gagatgaata catggatgtt ttagcagacg
     9421 gagcatggga aaacatcttc actgagaagc cagaagtctt tacaaaagaa gaaaagagag
     9481 aatggttaga taagttaaca gatgttacat tgggatctga tgcattcttc ccattctttg
     9541 ataacattga gagagcacat aagagtggtg taaaatacat cgcacagcca ggtggatctg
     9601 taagagatga cgctgtcatt gactgctgta ataagtacaa catggcaatg gcatttacag
     9661 gaatcagatt attccatcac taaaaagttt ctttatatag tcattgaaca tgaaaaacag
     9721 tatatggtct gaagtataat tttttggacc atatactgtt tttgtatgca aaaaaatatg
     9781 aaaaacagga gttattattt atttaacgag aaagtttatc ggttaagtat attgtattca
     9841 attttatttt tgctataatg taattgagtt agatagaact aaccaaagga gtttttataa
     9901 taattttaat ccaaaagaaa tggaggagtt ttcaaaatga aacagtttga agaatgggaa
     9961 ggatttaaag gtagaatctg gaaggaagaa atcaatacaa gagatttcat ccaggaaaac
    10021 tacacacctt atgatggaga cgaaagcttc cttgcaggat ctacagaagc aacagataag
    10081 ctatggggta tcttacaggg acttcagaaa gaagaacgaa aaaaaggtgg agttcttgac
    10141 atggatacag atatcgtatc ttctttaact tctcatggac ctggttatat cagtgaagaa
    10201 acaaaagatt tggagcagat cgttggtctt cagacagaca aaccattaaa acgtgcattt
    10261 atgccatatg gtggtatcaa aatggcagaa gaatcttgtc gtaactatgg ttatgaacca
    10321 agcgaaagat tacatgaaat ctttacaaaa tattcaaaga ctcataacac agctgttttc
    10381 gatgcttaca caccagaaat gaaaaaagca agacataaca agatcatcac gggtcttcca
    10441 gatacttatg gacgtggtcg tattgtaggt gactaccgtc gtgttgcttt atacggaatc
    10501 gactacttat tagaagaaaa agaaaatgat tttgcaaact gtggatgcgg tgttatgaca
    10561 gatgatgtga tccgtcttcg tgaagagatt gcagaacaga aaaaagcatt aaaaggtatg
    10621 aaagaaatgg ctaagatcta tggatttgac atttcaagac cagcaaaaac tgcaaaagaa
    10681 gcaatccagt ggatgtactt tggatactta gcagcgatca aaactcagaa tggagctgcc
    10741 atgagtatcg gacgtgtcgc tacattcctt gatatctata tccagcgtga ccttgacaaa
    10801 ggaatcatca cagaagaaga agctcaggaa atgatcgatc atttaacaat gaaattcaga
    10861 atggtaaaat tcgcacgaat tccttcttac aaccagttat tctcaggaga tccagtatgg
    10921 gcaacacttg accttgctgg tatcggtgta gatggacgtt ccatggtcac aaagacagac
    10981 ttccgtttct tacatacatt agagaacatg ggaccatctc cagaaccaaa catcactgta
    11041 ttatattctt ctgatcttcc agaaaacttc aagaaatatg cagctgacat ctctattcgt
    11101 acaagttcta tccagtacga aaatgatgat gttatgaaac cagtatgggg agatgattat
    11161 gcgatctgct gctgtgtatc tgcaactaag actggaaaag aaatgcagtt cttcggagca
    11221 agagcaaacc ttgcaaaatg cttattatat gcgatcaacg gtggtgtgga ctgcaagtca
    11281 aaacagcagg taggaccttc ttacaaacca atcacagctg aatatttaga ctatgacgaa
    11341 gttatggaga aatatgatgt tatgatggac tggttagtag atctttatgt gaacacatta
    11401 aacttgatcc agtatatgca tgacaaatat tactatgaag cagcggaatt agcattaatg
    11461 gatacagaac ttgaaagaac atttgcaaca ggaatcgcag gattctctca tgcagttgac
    11521 tctttaagtg cgatcaaata tgcaaaagta aaagcgatcc gtgatgaaga tggattagtt
    11581 gtagattatg aaatcgaagg agacttccct aaatacggaa acgatgatga cagagctgat
    11641 gatatcgcag tatggctgtt aagaacattc ttagctaaga tcaaaaaaca tcacacatat
    11701 cgaaactctg agcctacaac atctatcctt acgatcacat ctaacgttgt atacggaaaa
    11761 gcaacaggaa caatgccaga tggtagaaaa gcaggagaac ctttagcacc aggagcaaac
    11821 ccaagttatg gagcagaaca gaatggatta ttagcatcct taaactctgt agctaaactt
    11881 ccatatgaat gggcattaga tggtatttct aatacacaga cgatcaaccc agatgcatta
    11941 ggacatgaag agggtgaaag aatcaataac cttgtaaatg ttatggatgg atactttgat
    12001 cagggagctc accacttaaa tgtaaacgta tttggtaaag aaaaactgat cgatgcgatg
    12061 gaacatcctg aaaaagaaga atatgcaaac tttacgatcc gtgtatctgg atatgcagtt
    12121 aagttcatcg acttaacaag agaacagcag atggacgtta tttccagaac atgccatgca
    12181 acaatgtaat ttaaattagt ggaatagaac tatgaatgaa aaaataaccg gaaaaatcca
    12241 ttccatcgag acttttggtc tcgtggatgg tcccggtgtg cggtttatcg ctttcatgca
    12301 aggctgccgg atgagatgca aatattgtca caatccggag acttggcagg aaaactgcgg
    12361 tgaagactgg caggcagaag ccctcttaaa gagggctttg cgttaccgca tgtactgggg
    12421 aagtgatgga ggaattacag tcagcggtgg agaacccctt ctacagatcg agttcttgat
    12481 cgaatttttt aaattggcaa aacaagaagg aatccatact gcacttgata cctctgctaa
    12541 tccatataca aaagaagaac catttcacag caaatggtta gaattaatga aatacactga
    12601 ccttgtcatt ctagacttaa aagaaatgga cgaggaaaaa cataagaaat tgacaggctg
    12661 tccaaacagt aatattttag caatggcaca ggaaatctca gacctcggag tagatctgtg
    12721 gatccgtcac gtgctagtgc cagatttaac agacgatgaa aaaggactag cagacttaaa
    12781 acatttcatc gatggactaa agacagttaa gagagtggaa atcttgccat accatacact
    12841 tggactcttt aaatgggaaa aattagggat aaaataccca ttagaaggcg taaatccgcc
    12901 aagcgaagaa gctgtagcaa gggcagaaaa gattcttggt attgagaaag tttctcaaaa
    12961 ataaaggtag acaaaacatc cgagatagga tattataata acagttagtt aagactaact
    13021 agcataaaac aaaaacaaaa cataacaaag ctagaaaatc tgaccagact tccttgggtc
    13081 ggatttttta tttggctttt ttaagcgtgt tgaatatgta tgagtcaata aaaatggata
    13141 tgcgaaggct gagaaaaaga caaaagtgaa aaatcaaaga tagtttttgt atacaaattc
    13201 gttataatta tcactaatct tgacaaagac aagcttgatt tatataatgg ttataataat
    13261 aaccagttca gatagaagga agaacaatga aattaataga attatcagaa gtagaaatac
    13321 ttatcatgaa aagtatttgg aaacttgggg atgggattac ggtatatgaa attattgatt
    13381 atctagatca agtatatgat aggaaatata caagaagcac agtaaagaca tatatcacaa
    13441 aattaaagaa aaaaggattt gtagatacac aagtgaaagg caattacagc tatatcacag
    13501 caaagatcac agaagaaatg tatcgtgaag aacagatgga attgatgaag gatttctggc
    13561 atgatgggtc gatgaaagaa ttggttcaga cgttaacaca cacaatatca aaagaagaga
    13621 aagaggaatt aaaggatttg atcaatgatt tggatgatta aaaaaatata tatttatgtc
    13681 atcagtatga tactgctgaa tggtttggtg ggaagtattt cgtatctttg ctttcgcaag
    13741 ataaggcaac aactagagcg aaaaggactg atcagtatgt gcattactgt tttaagagga
    13801 gcagttttat catttctgat gccaatcgta attgtattga tctatttcat ttattatgta
    13861 tatgaagaag attatacaat gtttgcactg tctccattgg taggatgggt attttttgtt
    13921 gtaggaatca tttggacgat tggattttta aaagccatag tgaaaacaat acgtattcag
    13981 acacaaatga atcaattacg aaagagggca tgtgtatgca gtaaatctat tttagattgt
    14041 aagaatcaat ggaaagaaga agtaggtgtt cgtagaaatg tcgaaattaa aaccgtatat
    14101 gggttggcag taccgattat ttgcggattt ctaaaaccga tgattttgct tccagaaaga
    14161 gaatataaca aagaagaatt aaagattata tgcatccatg agttgattca ctgtaagcac
    14221 aaagatattt tgtggaaaca gttatgcgga cttgtaaggg tcattcattg gtggaatcca
    14281 ttggtaaagc aattagatat ggatgtagac agctggaatg aaacatactg cgatttagaa
    14341 tcaaccacaa ttatgaaaag caaaaaaaga tattttacga cgatctgtga aatcgggata
    14401 tcaccatttg caaaaggtgc atatctgtgc gcagcattag gagaagacaa aagccaatta
    14461 aagacacgaa ttttgagaat taaatcaatt gaaaacaaaa acacaaggaa tgtaatggca
    14521 ggaacattcc tttgtatagg attatccttt gtggtcgttg cggtaattat tctaagcacg
    14581 atcggctatc ataaaattta tgtagagaca gtctgggcaa cggaaataga agaggatctt
    14641 cctgaagaag agacagaata tacaatggat ttgaaagaat atactgcaaa aaggatcggg
    14701 acaaacttag cagttacaaa gctaaaacaa aatatcaaaa aaggagaaga aatagatgta
    14761 gttcagccat taaacgcaaa aacaaggcta gaaacaaaag agctggaatt aaaaaaaggc
    14821 gagaaaattg atttgaccgt tttttcatct caagaaatac aaagagagga taaggatttt
    14881 gtagcaggaa ttatagatgg gacaggaaaa gaacgatatg tgatgcatgc ggtcgatatt
    14941 atacatgact tttatgtgaa aaaagatgga aaatataaag tattcgttga aaatcgttat
    15001 aaaaagaaaa taaaaatagg aatagcgatt tgtgtggaga aatgataaat gaggaaatat
    15061 gtagttcgtt ttatggtatt ttatatatta agcattgggt gtttactggg aattattata
    15121 tattcgtatc aaaataagat tgatcgtcat aatgaacaag tggagataga ataccctgga
    15181 gtatggaagt tatcagatga atatgataat agaaattcta gctatatgga attccttcat
    15241 cagaaaaact ctctcagtat tttaaaaaaa gtatataaag aattagaaaa agcagagtta
    15301 tacagagaat attccagaca gattctatct tatcatgaat attttcgtgg gaatgaaaaa
    15361 cttgcatctg gatcatataa tgacaaaacg gaagatggat atcttacaaa tttaactgta
    15421 cttcagatgc cagagaaaat gataagtgaa aagaagatag aacaacatat tgaaaaaggt
    15481 cgttgcttta ctttaaaaga gtatcaaaga cctttgaatc aagagattcc attaattgca
    15541 ggatatgatt atcaaaaagt tttccatttg aatcagaaaa ttaaggcagg atatttggga
    15601 actgaaaatt gtacgtttaa aattgttggg tttttacata agaatactag gttgtcatcg
    15661 gaattaaatc ttgatgaaac attgattatg ccaacagtaa gtaaaatgaa aacaatgaaa
    15721 caagagaatg aaaaaatatt aatgtcagta aaatgttcag gttatttttg ttataagaat
    15781 gagaaagagt atcgtcaaat aagtaatttg ctaaaaagaa tacgcaggga gacaggttat
    15841 cgttatgtga taccgcagat gaaatggaaa tcaaataatt tattaccaat gacaactgaa
    15901 aaagcattga tattcatgag tttaaatttg ctactagaat tcatcgttgt atataaagta
    15961 ctggctgtga atacaagaaa agtgaaaaca ttggtatata aaacagtagc cctatgtaca
    16021 agtgggagta tatttgcaaa tgtatttttg cggttcttgt ttcctaaaca cataaaaata
    16081 attcaaatat attcttctga ttttgtggct tatatgataa tagtattttt gttatgtgca
    16141 ggaatgattg gattaaagga gaaaagaaca tgatggagaa gattctgctt gggagtagtt
    16201 atctagctca agctattgtt atggcaacga ttgcatttgc agtcataagc acaatttact
    16261 atttacgata taataaaaag attatatgtc agccaggatg gatcataaaa tacatatttt
    16321 tggtttacat agcaaccgtt ggcatggtca cgagagtatt agacatcaca tcatggtcat
    16381 atggaggatt tacagcctgg aatattgtac catttgtgaa tgaaagctgg aaattgatgc
    16441 tgttaaatac attaatgttt ctgccaatgg gactttttgt tcctatattt ataaagaaaa
    16501 taaaatggaa ctatggaaaa gcaataattg tagggacatt gatatctttg atgatcgagt
    16561 ttgtacaagt tgtatttgca ggaagaattg gtgatattga tgatatcatt tttaatacat
    16621 taggatttct gatcgggtat atcctagaga acctgttgca aaaaattctt ttaaaaaagc
    16681 aattaggatt tggaacagag gcattggtac tggttatgat caatggattt ctaagtatcc
    16741 cattttatga gaagacggtg tcaattggag atatgatttt ggatagtttg aatctcaaca
    16801 gttggtcagg aaatagtgga tatatattgt catataacgg catccattac acaatgatcc
    16861 catgtataat actagcagtc atcagctggg ctatagcaca tagatatcca aaagactatg
    16921 gtgctaaaac agcgaaaata atcagtatat ttatgattgt ttgcttcatt ggaaatttta
    16981 ttcagatttt aagtcaagat agtattatac caatgcttgc tgcatccatt gtgtgtgcgg
    17041 taataagtcg aaaaactatt agatattagg gatttgatat tccatgaaaa atatgagata
    17101 ctatagtata aaacgttaag gagaataaga tatgaaaaaa ttatcaatac tacttgcagg
    17161 ggtatgctta acagctgcgt tatacggcgc aggtacaatc tatggacaaa acaaaaccaa
    17221 caccgcaaaa caaagcgaag acaaagtcac aacaaacaaa taccaaggcg taacgatcaa
    17281 agacaaagcc aaaggaaaag tgacaaagca acaagttaag cagttaaaaa aagaacattc
    17341 cggcaaagat gaaggaaaca tcatcatctg ggaagcagaa gaagccgaat agagggggcg
    17401 aagaaatgtt aataccagat ttaatcatac agctgattac agtagttatt ggagtggcac
    17461 tatatgcagc tatatttaaa atagtaaaaa atgtgattca taaaataata tattaaagca
    17521 gtcagtatca atgttggtaa agtgttaaga actaaccaat acattttatt attccatggt
    17581 tattgccaat aaacttcaga tatgtaagtg aaaattataa ttgcaatcaa aaaatagttg
    17641 ctggtgaaca acgattagca ttttatcatt atttttgatc gattcgcagc cgacatggtg
    17701 tattgtctga gcgatatgga agtcattttg gacttccata agcgagttat acaaggaatg
    17761 tcggcgaaca agcgatcggt caaaaatgat gaataaaatg cgtgttgttc accagcaact
    17821 attttttgat tgcaattata atttttactt acatattcaa agactatgtc aaagaaactc
    17881 tatacattaa agcggaacac aataatatcc ccatctttaa caacatattc tttcccttcc
    17941 tgacgtacaa gccctttctc cttacaagcc tgcatcgtac catactcctt caaatcttca
    18001 aaagaaacaa cttcagcaca gataaatcca cgctcaaagt ctgtatggat cttaccagca
    18061 gcctgaggag cttttgtacc ttctttgatc gtccaagcac gtgtctcgtc ttctccggaa
    18121 gttaagaaac tgatcagtcc aagaagagag tagctggcag agatcagttt ttcaagacca
    18181 gattcttcta atccaagatc ttctaagaat tctttcttct catcatcatc taattcagag
    18241 atttcctgtt caatctgagc acatacaacg aatactttcg catcaacgtc tgcagcatac
    18301 tcacggacag cttttacata atcattatct tctccagcaa gttcatcttc gttaacgttt
    18361 gcagcaaaga tcactggttt gatcgttaac aggttgcagg aatttaggat ttcctgatct
    18421 tcttcatcat cgacttcgaa tgtcttagca agctttccat cttccagatg agcttttacc
    18481 ttagataaga attcaacttc gtgagcaaga gatttatcat ttcttgatcc ttttgttgat
    18541 tttgcgatac gacggtctaa cacttcgata tcagagaaga tcagctcgaa gttgatcgtt
    18601 tcgatatcac gaagtgggtt tacagaaccg tcaacgtgaa cgatatttcc atcatcaaaa
    18661 caacgaacaa cgtgaacgat cgcatcgact tcacggatat ttgcaaggaa ctggtttcca
    18721 agaccttccc ctttggaagc tcctttcaca agacctgcga tatcaacgaa ttcgatcgct
    18781 gcagggatca ctttctttga atggtatttc tcagccagat aatcaacacg agcatctgga
    18841 actgttacga ttcccacatt agggtcgatc gtacagaatg gatagttagc ggattcagca
    18901 ccggcttttg ttaaagagtt aaataatgta ctctttccga cgtttggtaa tccaacgatt
    18961 cctaatttca taatctatta atttcctttc tcatgggtat ttcttaaaac agaccttgaa
    19021 aaaatatcca aggtcatact gtagatagtt taccataagc gacttgaaaa gaaaagagaa
    19081 atgggataag atatctttga tttgagtaac aaaacaaaga agagacaaaa cgaggcttta
    19141 gaaaggaaga aaagtgatgg aacatcaaat cagattccca catttaggga tcgtactgaa
    19201 aaatgtcggt gatggaatca atattggagg gtttgagatc aaatattatg gaatgatcat
    19261 tgcaacagga ttcttgcttg gattgatcgt ttcttattac gcagcaaaac atgaaaataa
    19321 atttgatccg gaattagtct ttgactatct gatcacgatg atcattccgg cgatcgtagg
    19381 agcaagactc tattatgtga tcttttcatg ggattattat aagaatcatt tgtcagagat
    19441 catacagatc agaaatggag gacttgcaat ttatggaggt gtgatcgcag gtgcaatcac
    19501 attatatatc ttctgcaaga agaaacattt atctatgctt cagtttggag atgtggcggt
    19561 aaaagggctg cttgtcggtc agattcttgg acgatggggc aatttcttta acagagaagc
    19621 gtttggatca tataccaaca gtttatttgc aatgcagatt ccgacaaatt tctttattga
    19681 acacggaagg attgatgaga tcgtatccaa tggattgtat gataaggcaa cttatgttgt
    19741 atctggaaat gaagcagcaa cctttattca ggtacatccg acattcttat atgaatctat
    19801 gtggaatctt gttttactac tgttgatcat tttctttttt acgaagagaa aaaaatttga
    19861 tggagaattg attgccattt attgtattgg ttatggaatc ggaagatttt tgattgaagg
    19921 attaaggacc gattccctga tgatcggatc tacaggaatc agggtatccc agatcttagc
    19981 actgatcctt gcagtatttg gaacggcatt tattatgtat aaaaggaaga aaataacgaa
    20041 ataagacaca aaaagaaggg aaataaaacc acttttaggg aatcccttct tttttgtgca
    20101 aaaaaacaag gatttctaag aaaaaactaa gatttgattg tggattattc cttgcaattt
    20161 ataagtctat cgtataaaat gaaatttata agtggtaaga agtggtggaa agtggtgatg
    20221 tccatgttta tgggggaatt taatcacacg attgatgcaa aaggcaggct gatcattcct
    20281 tcacgattcc gggaagaatt aggtcaggaa tttgtgatga caaagggatt ggatggatgc
    20341 ctgtttgtgt tcccacaaaa cgaatgggaa agttttcaag ggaagctaaa aactttgcca
    20401 cttattaata aagatgccag aaagttttcg agatttttca tggcaggggc agctccatgt
    20461 gagatggaca agcagggaag aaccttgatc ccagcgacac ttcgggaatt tgcccagatg
    20521 aagaaagaag ttgtattaac aggaatggct gaccacatcg aaatctggag taaggagaag
    20581 tggattgaga acaattctta tgaggatatg gatgatattg cagccagcat gcaggaatta
    20641 ggattaagca tataagttag gtggattatg gaatttaaac acatttccgt tttattagac
    20701 gaaacgatcg aagaactaca tattaaacca gacggaatct atgtggatgg gactctgggc
    20761 ggaggcggac atgcatatca tgtatgccag aaactatcag agaaaggaag atacatcggg
    20821 atcgaccagg atgcggatgc gattgctgca agcacgaagc ggttagaacc gtttaaggac
    20881 aaagtaacga tcgtgcgtga taattatgta aacatgccga aagtgttaca tgatcttgga
    20941 atcgaacatg ttgatggaat cttgttagat cttggggtat catcctttca gttagatgag
    21001 aaggaacgtg gatttactta cagagaagat gttccgcttg atatgagaat ggatcagaga
    21061 cagtcactga ctgcaagaga tattgtcaat gaatattccg agatggaact attccatata
    21121 atcagagact acggcgaaga gaaatttgca aagaacattg caaaacatat cgtgaataag
    21181 agaaaagaaa gtccgatcga aacgaccgga cagttaatag aagtcatcaa aggtgcgatc
    21241 ccgatgaaag tcagagccgt tggaggacat ccggcgaaga agacatttca ggcgatccgt
    21301 atcgaatgta acagagaatt agacgtattg aaagacagca ttgatgcgat gatcgatctt
    21361 ttaaatccag gtggaagatt atgtatcatt accttccatt ctttagaaga ccgtatcgtc
    21421 aaacgagctt ttaagaagaa tgagaatcct tgtacatgcc cgccaaactt cccagtatgt
    21481 gtatgtggca acgtatcgaa aggaaaacag ttaacaagaa aaccaatcat tccaggggaa
    21541 gaagaactag agtacaataa gagagcaaaa agttccaagc ttcgagtatt tgaaagggca
    21601 gaataaggga gagtatcaat ggacaaaacg agacaagaac gatataacat gatctatggc
    21661 aacacagcaa ggaagataga agatcttgct gcagagccag tgcgcagaca gccaaggaag
    21721 acaagaaagg caagaccaag aagagaacat caggtaaagg agtcaacaag acagaatcag
    21781 aagagagcga tgtcgattga tttggccttt atcaaggtat tagttgcggg actttgtgtg
    21841 atcgcagttg caagtttctt ttatctgtca gagcgtacga aagttttgaa tcaaaaagcg
    21901 gctcttacgg atgcaaagac acagttgaac acgctgcagg tagagaatga agatctgaat
    21961 cttgagattg aacagagtat tcgttttgat actgtagaaa ctgcggcaaa gaaatatgga
    22021 atggtgaaac cagattccaa acatactctt cgttatgaga gccaggatgc agaatacata
    22081 cgccagtacg ggaagatacc aaaagcagac taa
//
