LOCUS       NC_017168.1            21763 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_017168.1 Yersinia pestis A1122, complete sequence.
ACCESSION   NC_017168
VERSION     NC_017168.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:55:30
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1938259
            Orig. end    :: 1960022
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21763
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[1948259:1950022]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..11763
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..21763
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..21763
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Putrescine2spermidine"
                     /region_number="8"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             759..2288
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) oxoacid_dh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 75.1; E-value:
                     9.5e-24)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1696"
                     /sec_met_domain="Biotin_lipoyl (E-value: 3e-22, bitscore:
                     76.1, seeds: 40, tool: rule-based-clusters)"
                     /sec_met_domain="oxoacid_dh (E-value: 5.3e-81, bitscore:
                     269.4, seeds: 75, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIEINVPDIGADEVEVTEIMVKVGDTVEAEQSLITVEGDKASME
                     VPSPQAGVVKEIKIAVGDKVATGSLIMVFDATGAAAAPVKAEEKPAAPAQVAAPAASAA
                     KNVEVPDIGDDEVEVTEVMVKVGDKVDAEQSLITVEGDKASMEVPAPFAGIVKEIKIST
                     GDKVKTGSLIMVFEVEGAAPAPAAAPAAKAESKGEFAENDAYVHATPVIRRLAREFGVN
                     LAKVKGTGRKGRILREDIQAYVKDAVKRAEAAPAAAGGGLPGILPWPKVDFSKFGEIEE
                     VELGRIQKISGANLSRNWVMIPHVTQFDEADITEVEAFRKQQNIEAEKKKQDLKITPLV
                     FLMKAAAKALEEFPRFNSSISEDGQKLTLKKYINIGVAVDTPNGLVVPVFRDVNKKGIV
                     ELSRELSVISKKARDGKLTASDMQGGCFTISSLGGIGGTAFTPIVNAPEVAILGVSKSS
                     MKPVWNGKEFAPRLMLPLSLSFDHRVIDGAAGARFAAYIATIMADIRRLVM"
     CDS             2594..4018
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_dim"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1697"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.5e-62, bitscore:
                     209.4, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="Pyr_redox_dim (E-value: 4.4e-36, bitscore:
                     121.4, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTEIKTQVVVLGAGPAGYSAAFRCADLGLETILVERYSTLGGVC
                     LNVGCIPSKALLHVAKVIEEAKALAEHGIVFGEPKTDIDKVRVWKDKVINQLTGGLAGM
                     AKGRKVKVVTGFGKFTGANTLVVDGENGPTTINFDNAIIAAGSRPIQLPFIPHEDSRIW
                     DSTDALALRTVPERLLVMGGGIIGLEMGTVYHALGSKIDVVEMLDQVIPAADKDVVKVF
                     TKRISKQFNLMLETKVTAVEAKEDGIYVTMEGKKAPAEPQRYDAVLVAIGRVPNGKLLD
                     AGQAGVEVDDRGFIHVDKQLRTNVPHIFAIGDIVGQPMLAHKGVHEGHVAAEVIAGMKH
                     YFDPKVIPSIAYTEPEVAWVGLTEKEAKEKGISYETSTFPWAASGRAIASDCADGMTKL
                     IFDKETHRIIGGAIVGTNGGELLGEIGLAIEMGCDAEDIALTIHAHPTLHESVGLAAEI
                     YEGSITDLPNPKAKKK"
     CDS             4261..4719
                     /locus_tag="ctg1_1698"
                     /transl_table=11
                     /translation="MRDEKSLAHTRWNCKYHIVFAPKYRRQVFYREKRRAIGSILRKLC
                     EWKNVNILEAECCVDHIHMLLEIPPKMSVSGFMGYLKGKSSLMLYEQFGDLKFKYRNRE
                     FWCRGYYVDTVGKNTARIQEYIKHQLEEDKMGEQLSIPYPGSPFTGRK"
     CDS             5289..7886
                     /locus_tag="ctg1_1699"
                     /transl_table=11
                     /translation="VLEEYRKHVAERAAEGIVPKPLDASQMAALVESLKNPPAGEEEFL
                     LDLLTNRVPPGVDEAAYVKAGFLAAIAKGEAHSPLITAEKAIELLGTMQGGYNIHPLID
                     ALDNEQLAPIAAKALSHTLLMFDNFYDVEDKAKAGNPYAKQIIQSWADAEWYLSRPALA
                     EKLTVTVFKVTGETNTDDLSPAPDAWSRPDIPLHALAMLKNAREGIHPDQPGSVGPIKQ
                     IEELNKKGFPLAYVGDVVGTGSSRKSATNSVLWFMGDDIPYVPNKRGGGVVLGSKIAPI
                     FFNTMEDAGALPIEVDVAKLNMGDVIDIFPYQGEVRRHDTGEVLATFELKTDVLLDEVR
                     AGGRIPLIVGRGLTTKARESLGLPVSDVFRVPKPVAKSNKGFSLAQKMVGRACGVAGVR
                     PGEYCEPKMTSVGSQDTTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPKPVDVTTHH
                     TLPDFIMNRGGVSLRPGDGIIHSWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAF
                     AAATGVMPLDMPESVLVRFKGEMQPGITLRDLVHAIPYYAIQEGLLTVEKKGKKNIFSG
                     RILEIEGLPELKVEQAFELADASAERSAAGCTIKLDKAPITEYLQSNVVLLKWMIAEGY
                     GDRRTLERRINGMESWLANPSLLEGDADAEYAAVIEIDLAEITQPILCAPNDPDDARLL
                     SDVANSKIDEVFIGSCMTNIGHFRAAGKLLDQHKGQLPTRLWVAPPTKMDAAQLTEEGY
                     YSVFGKSGARIEIPGCSLCMGNQARVADGATVVSTSTRNFPNRLGTGANVYLASAELAA
                     IASLLGRLPTPDEYQTYMAQVDKTAEDTYRYLNFDQLSQYTDKADGVIFQTAV"
     CDS             8185..8544
                     /locus_tag="ctg1_1700"
                     /transl_table=11
                     /translation="MDYEFLRDLTGQVLVKFSMGHEVIGHWLNEEIKGDLVKLDHIETA
                     ADGVRGSERQWQLPGHEYTLWLDGEEVMVRANQLDLDGDEMEEGMNYYDEESLCLCGLE
                     DFLLVLKGYRAFITQ"
     CDS             complement(8655..9563)
                     /locus_tag="ctg1_1701"
                     /transl_table=11
                     /translation="MNRLPTLYGIIAILLWSMSVALTRGLAEALGPFGAGSAIYSVSGI
                     LVWLVAGKPRVRGQHPAYLYGCGLLFVVYMVAFALAIGMANDRQQTLEIGLINYLWPSL
                     TLLLAVPLLKLRARWWLWPGAALALFGVIWVVSGGEGLDVKTLAVNISSNPLAYSLALI
                     AAFTWAGYSNLVRLYSQGPGALPLFLIACALCLWLMFFMWTPGKLHFTPRAIFELLLMG
                     ANTALAYQCWDRAYQCWDSAMKKGNATLVAALSYFTPLLSILIASVWLNTLPSAAFWPG
                     VAMVVAGSLLCWSASRNPLRT"
     CDS             complement(10001..10795)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: AdoMet_dc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1702"
                     /sec_met_domain="AdoMet_dc (E-value: 1.1e-29, bitscore:
                     100.8, seeds: 266, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LSKLKLHGFNNLTKSLSFCIYDICYAKTADDRDGYIAYIDEQYNA
                     NRLTEILSETCSIIGANILNIARQDYDPQGASVTILVSEEPVDPRDVDTSEHPGPLPSA
                     VVAHLDKSHICVHTYPESHPEAGLCTFRADIEVSTCGVISPLKALNYLIHQLESDIVTM
                     DYRVRGFTRDINGVKHFIDHKINSIQNFMSDDMKSLYHMMDVNVYQENIFHTKMMLKDF
                     DLKHYLFNAKPEELSAEEKEQITRLLYKEMQEIYYGRNVPEV"
     CDS             complement(10873..11763)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1703"
                     /sec_met_domain="Spermine_synth (E-value: 1.4e-67,
                     bitscore: 224.7, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 2.3e-18,
                     bitscore: 63.7, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQKELWYETLHANFGQYFSVENVLFREKTEHQDLVIFENPELGR
                     VMALDGVVQTTERDEFIYHEMMTHVPLLAHGQAKKVLIIGGGDGAMLREVSRHKNIEQI
                     TMVEIDAGVVEFCRQYLPNHSAGAYDDPRFKLVIDDGVNFVNQTTEKFDVIISDCTDPI
                     GPGESLFTSVFYEGCARSLNEGGIFVAQNGVCFLQQDEAVNSHNKLSHYFSDVSFYQAA
                     IPTYYGGIMTFAWATQNPALRQLDLATLQNRFAQAGLACRYYNPAIHVGSFALPQYLLD
                     ALTTIPKVIGVDSSE"
     CDS             complement(11880..12227)
                     /locus_tag="ctg1_1704"
                     /transl_table=11
                     /translation="MKRTTLVMLLLTLCGFSSASFALSESEAEDLADLTAVFVYLKNDC
                     GYQELPNNEIKRAIVYFAQQNRWDLHNYDSFNMKALGEDSYRDLRGIALPTPVKCKSLA
                     RDSLSLLAYAN"
     CDS             12544..14145
                     /locus_tag="ctg1_1705"
                     /transl_table=11
                     /translation="MHRRDFLKLTAALGAATSLPLWSRAALAADFSPLPIPPLLQPDAN
                     GKINLNIQTGSVVWLPSTATQTWGYNGNLLGPAIRLQRGKAVTIDITNALPEATTVHWH
                     GLEIPGEVDGGPQALIQPGAKRQVTFAVEQPAATCWFHPHTHSKTGHQVAMGLGGLVLI
                     DDSDSETLPLPKQWGVDDIPVILQDKLLDKHGQVDYQLDVMTAAVGWFGDRMLTNGVPY
                     PQQITPRGWVRLRLLNGCNARSLNLALSDGRPMYVIASDGGLLAEPVVVRELPILMGER
                     FEVLVDTRDGQSLDLVTLPVTQMGMTLAPFDQPLPVLRIQPSLAIGSQVLPESLVVIPE
                     LADVTGVQERWFQLMMDPKLDMLGMQALVARYGMKAMAGMNMNHGDMGAMDHGNRPDMS
                     QGKMKGMDHGTMNGAPAFNFSHANRINGKAFSMTEPAFDAKQGKYEKWTISGEGDMMLH
                     PFHVHGTQFRILTENGKPPAEHRRGWKDIVRVEGARSEILVRFNYLAPASTPYMAHCHL
                     LEHEDTGMMLGFTVSA"
     CDS             14365..14901
                     /locus_tag="ctg1_1706"
                     /transl_table=11
                     /translation="VRHTVEVMISEQEVKTRIAELGRQISEHYRDSGSDMVLVGLLRGS
                     FMFMADLCRAIDVSHEVDFMTASSYGNGMSTTRDVKILKDLDEDIRGKDVLIVEDIIDS
                     GNTLSKVREILQLRGPKSLAICTLLDKPERREVHVPVEWVGFTIPDEFVVGYGIDYAQR
                     YRHLPYVGKVVTLDE"
     CDS             complement(15055..15930)
                     /locus_tag="ctg1_1707"
                     /transl_table=11
                     /translation="MGLLVVLRTHDVFNPPHMRDVTGNIKNQTGTEKILRRQYRVITET
                     TVPISKSESLPYIILSQPEHYRLFTLMKEIEKLIANNRTWSNTICKDDPGFFEHLAQSQ
                     KPRFLWIGCSDSRVPAEQLTGLKSGELFVHRNVANLVIHTDLNCLSVVQYAIDVLQVEH
                     IIICGHLGCGGVEAAIKGEEMGLIDNWLLHIRDLWYKHSSLLGELPQEERSNVLCQINV
                     VEQVYNLGHSTIVRSAWKRGQKAMIHGWVYGIENGLLRDLEVSATSLGSLEMVYRKAMA
                     ELLQNNKEDH"
     CDS             15953..16879
                     /locus_tag="ctg1_1708"
                     /transl_table=11
                     /translation="MTYALEITQLTKTYMGGVQALRGIDLHVEAGDFYALLGPNGAGKS
                     TTIGIISSLVNKTSGKVQVFGYDIDNDIVNAKRQLGLVPQEFNFNPFETVLQIVITQAG
                     YYGVTRRDALARAEKYLSQLDLWSKRDERAIRLSGGMKRRLMIARALMHEPKLLILDEP
                     TAGVDIELRRSMWGFLKELNAQGTTIILTTHYLEEAEMLCRNIGIIQNGELVENTTMKQ
                     LLSKLESETFIFDLGAKSPLPKLEGYGYRLTDTSTLEVDVKREQGLNSLFSQLNVQGVQ
                     VQSMRNKANRLEELFVTLVNGHEGEKA"
     CDS             16876..17646
                     /locus_tag="ctg1_1709"
                     /transl_table=11
                     /translation="MTRLYWIALQSIWIKEITRFARIWIQTLVPPVITMSLYFVIFGNL
                     IGARIGDMGGFDYMQFIVPGLIMMAVITNAYSNVAASFYGAKFQRSIEELLVAPVPTHI
                     VIIGYVGGGVARGICVGILVTIISLFFVPLHVHSWSMIALTLILTAILFSLGGLLNAVF
                     AKTFDDISLVPTFVLTPLTYLGGVFYSLSLLPPFWQAVSKLNPIVYMISGFRYGFLGIT
                     DVSLAYTIGVLVVFIAVFYAWAWYLIERGTGLRT"
     CDS             17853..19166
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_deac_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1710"
                     /sec_met_domain="Polysacc_deac_1 (E-value: 4.1e-19,
                     bitscore: 66.6, seeds: 80, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWHKNRIAIGMLLSIVMWVIMIPTTQADLLPNVEVTPPKYMMTER
                     DSEVYSLVGEHVIPVGEIKEGQLIQVTPVIAEYYEFKFGNGTGFIDKDDLREINKAQKN
                     NDMLGDLNKPLPNQNILTMREAKVYLAADVRSEQFAVLAENLRYPIVGKLKDRLSNTWY
                     QVNIGDRLGYVSSADAEIDNGIPILTYHHMLKNEENKRFLNTSTTTSDVAFSNQMAYLK
                     QAGYDTISLYQLEGYLNNKINLPAKVVVLTFDDGLKSVSRYAYPILKENGFRATAFIIS
                     SRIKRHPQKWNPDSLQFMSIAELKGIQDVFDIQSHTHFLHRTDNRHHPILLSRSYHNII
                     FDFERSRRALAQFNPHVIFLSYPFGGFNQTAVNAAKNAGFHLAVTTMQGKVKPGDNPYT
                     LKRLYILRTDSIPTMAERIANQPGPVAVKPAPAVIEMD"
     CDS             complement(19315..19695)
                     /locus_tag="ctg1_1711"
                     /transl_table=11
                     /translation="MIRTMLQGKLHRVKVTQADLHYEGSCAIDQDFLEAAGILEYEAID
                     IYNVDNGQRFSTYAIAAERGSRIISVNGAAARCACVGDKLIICSYVQMSYAAARLHHPK
                     VAYFEGENQLQRKAKAVPVQVA"
     CDS             complement(20106..20960)
                     /locus_tag="ctg1_1712"
                     /transl_table=11
                     /translation="MLIIETLPLLRQQIRRWRQEGKRIALVPTMGNLHEGHMTLVDEAK
                     TRADVVVVTIFVNPLQFERPDDLAHYPRTLQEDCEKLTRHGADLVFAPAAADIYPAGLE
                     KQTYVDVPALSTILEGASRPGHFRGVSTIVSKLFNLIQPDVACFGEKDYQQLALIRKMV
                     ADMGYDINIVGVPTVRAKDGLALSSRNGYLTEEERQIAPQLSKIMWALAEKMALGERQI
                     DALLEEAAAQLLRVGFTPDELFIRDAETLQPLTVDSQQAVILMAAWLGKARLIDNQLVD
                     LRH"
ORIGIN
        1 acatgaagat ggtcatagcc atattcagtc actgactatc ccgaactgta tctcttacga
       61 tccggcctat gcttacgaag tcgccgtcat tatgcatgac ggtctggagc gtatgtacgg
      121 cgaagcgcag gaaaacgttt attactacct gactacgctt aacgaaaact atcacatgcc
      181 agcgatgcca cagggcgcag aagaaggtat ccgtaaaggt atctataaac tggaaactgt
      241 tgaaggtagc aaaggcaaag tgcagctgat gagctctggt gcaatcttgc gtcacgttcg
      301 cgaagcggct cagattctgg ctaaagatta cggcgtaggt tctgatgtgt acagtgtgac
      361 ctccttcact gaactggccc gtgacggtca ggattgtgag cgttggaaca tgctgcaccc
      421 gacagaaaca ccacgtgttc cttatgtggc tcaggtgatg aatgatgccc ctgcggttgc
      481 gtctactgac tacatgaagt tgtttgctga acaaattcgt aactttattc ctgccagcga
      541 gttccgtgta ctgggcactg acggtttcgg ccgttctgac agccgtgaga acctgcgtca
      601 ccacttcgaa gttgattctt cttatgttgt ggttgcggct ctgggtgaat tggcgaaacg
      661 cggtgacatc gacaccagtg tagttgctga agcaattact aagtttggta tcgacgctga
      721 taaagttaac ccgcgtctgg cataagaggt agagaataat gtctatagaa attaatgtac
      781 cagacatcgg tgcagatgaa gtggaagtca ccgaaattat ggtgaaagtg ggcgataccg
      841 ttgaagcgga acagtcgcta atcaccgttg aaggcgataa agcttccatg gaagttcctt
      901 cacctcaggc gggcgtggtt aaagagatca aaattgcggt tggcgataaa gtggctaccg
      961 gttctctgat catggtcttc gacgctacgg gtgccgctgc ggcaccggtt aaagcagaag
     1021 aaaaaccggc ggcgcctgct caggtagcgg ctccggcagc ctctgcggcg aaaaatgttg
     1081 aagtgccaga tatcggtgat gacgaagttg aagtgactga agtgatggtg aaagtgggcg
     1141 ataaagttga cgccgaacaa tcactgatta cggttgaagg cgacaaagcg tcgatggaag
     1201 tgcccgcacc gtttgctggt atcgtgaaag aaatcaaaat cagtaccggc gacaaagtga
     1261 aaaccggctc tctgattatg gtcttcgaag ttgaaggtgc agcgccagcg ccagccgccg
     1321 cacctgccgc caaagcagaa agcaaaggcg agtttgccga gaatgacgct tacgtgcatg
     1381 ccacgccggt tatccgtcgt ctggcgcgtg agttcggtgt gaacctggcg aaggtgaaag
     1441 ggacaggccg taagggccgt atcctgcgcg aagacattca agcttacgtg aaagatgccg
     1501 tgaaacgtgc cgaagctgca ccagcagcgg ctggcggcgg cctgccgggc atattgcctt
     1561 ggccaaaagt tgatttcagt aaatttggtg aaatcgaaga agtcgaattg ggccgtatcc
     1621 agaaaatttc tggtgcgaac ctgagccgta actgggtcat gatcccacat gtgacgcaat
     1681 tcgatgaagc ggatatcact gaagttgaag ccttccgtaa gcaacagaac atcgaagctg
     1741 agaagaaaaa acaagacctg aaaatcaccc cgctggtgtt cctgatgaag gccgccgcta
     1801 aagcactgga agaattccca cgctttaaca gctccatttc cgaagatggt cagaaactga
     1861 cgctgaagaa atacatcaat atcggtgtgg cggttgatac gcctaacggc ttggtagttc
     1921 cagtattccg tgacgtcaac aaaaagggta ttgtcgagtt gtctcgtgag ctatctgtca
     1981 tctccaagaa agcacgtgat ggcaagctga cagcatctga catgcaaggc ggctgtttca
     2041 ctatctccag tctgggcggt atcggcggta cggcatttac gccaatcgtc aatgcgccag
     2101 aagtggctat cttgggtgta tcaaaatcat ccatgaaacc tgtctggaat ggtaaagagt
     2161 ttgctccacg cctgatgtta ccgctgtctc tgtccttcga tcaccgtgtg attgatggtg
     2221 ccgcgggtgc acgcttcgcc gcgtatatcg ctaccattat ggcggatatt cgccgtctgg
     2281 tgatgtaatc gccaaggccg gcttcgtgcc ggccttgttg tggttactgc tcttgttatt
     2341 ggtgatcttg ttattactga tcaccaatag agaaaagaca cttataaacc ggctttgtca
     2401 ggctgttaca ttagtcgaca aggttgttga gacactggtc acgcgatgcg gcttttcagt
     2461 ttattaacaa ttctgtaaac tgcccgcgag tcagttcccg gtataagagc gtcccggtgg
     2521 atgagggcgt tatgaaattg attcgcctaa aaaatgatgt cagacccgcc ggacaaacaa
     2581 ttaagaggtc atgatgagta ctgaaattaa aactcaggtc gtggtacttg gggcaggtcc
     2641 agcagggtac tctgctgctt ttcgttgtgc ggatttaggg ttagaaacca ttctggttga
     2701 acgttactcc actctggggg gggtttgcct gaatgtgggt tgtatccctt ccaaggcact
     2761 gttacacgtt gccaaagtga tcgaagaagc caaagcgctg gctgaacatg gtatcgtttt
     2821 tggcgagcct aaaactgata ttgataaagt ccgtgtctgg aaagataaag ttatcaatca
     2881 gttgaccggt ggtttggcag gtatggctaa aggccgtaaa gtcaaagtag tgactggttt
     2941 tggtaaattt accggtgcga acaccttagt ggttgatggt gagaatggtc caacaaccat
     3001 taacttcgat aacgctatta tcgcggcggg ttctcgccca attcaactgc cattcattcc
     3061 tcatgaagac tcacgtattt gggattcaac tgacgcactg gcattgagaa cggttcctga
     3121 gcgcttgttg gtgatgggcg gtggtatcat tggtctggaa atggggaccg tttaccacgc
     3181 actgggttct aagattgacg tggtcgaaat gcttgatcag gtgatccccg cagcagataa
     3241 agacgtggtg aaagtcttta ccaagcggat cagcaagcag ttcaatctga tgctggaaac
     3301 caaagtgaca gcggtagaag ccaaagaaga cggtatctat gtcacgatgg aaggcaaaaa
     3361 agcgccagca gagccacaac gctatgatgc ggtgttggtt gcgattggcc gcgtgcctaa
     3421 cggtaagttg ctggatgcgg gtcaggcggg tgttgaagtt gatgatcgtg gctttatcca
     3481 cgttgataag caactgcgca ccaatgtgcc acacattttt gctatcggtg acatcgtggg
     3541 tcagccaatg ctggcgcata aaggtgtcca cgaaggccat gttgccgctg aagttatcgc
     3601 aggcatgaag cactatttcg atccgaaagt tattccatcg attgcgtaca ctgaaccaga
     3661 agtcgcatgg gttggtttga ccgaaaaaga agcaaaagag aaaggcatca gctacgaaac
     3721 ctccaccttc ccgtgggcgg catcgggccg tgctatcgct tctgattgcg cagatggtat
     3781 gactaaactg attttcgaca aagaaactca ccgtatcatt ggtggtgcga ttgtcggtac
     3841 taacggtggc gaactgttag gtgaaatcgg tctggccatt gagatgggtt gtgatgcaga
     3901 agatatcgca ttgaccattc atgctcaccc aacattgcat gaatcagtgg gcctggcggc
     3961 ggaaatctac gaaggtagca ttactgacct gcctaacccg aaagcgaaaa agaaataatt
     4021 ttttgttgat gctgcattta cagatgtgaa tgtacagagg taaatgtaca gcaataaata
     4081 aaagtgaaac ggtccctaca taggggccgt tttttttgtg cccagaaaac ccccagctag
     4141 gctgggggtt cagtaaagct ttcagctttg ggtcagttat aaaaacccct tttgatttgt
     4201 taaaacagtt tgcggtctgg caactgcaaa tgttcaacaa gaaatcaaaa gggggtccca
     4261 atgagggatg aaaagagctt agcgcacacc cgatggaact gtaaatatca tatagttttt
     4321 gcgccgaagt accgaaggca ggtgttctac agggaaaaac gcagagcgat tggcagtatt
     4381 ttaagaaaac tgtgcgaatg gaaaaacgtg aatatcctgg aagcagaatg ctgtgtggat
     4441 cacatccata tgcttctgga gatcccgccc aagatgagtg tctcgggatt tatggggtac
     4501 ctgaagggaa agagcagtct gatgctttat gagcagtttg gcgatttgaa gttcaaatac
     4561 cgtaacaggg agttttggtg tcgagggtat tacgttgata cggtagggaa aaacacggcc
     4621 aggatacaag aatacataaa gcaccaattg gaagaggata aaatgggtga gcaactctcg
     4681 atcccgtatc ccggtagccc gtttacgggc cgtaagtaat ccatagatgc aaatgtcaga
     4741 tcgcgatgcg cctgttaggg cgcggctggt aacagagcct tataggcgca tatgaaaaac
     4801 ctccggctat gccggaggat atttatttta gcctatacgc ggtagttaag tgtagcgact
     4861 cagagagatg gtatcctctc attggttatg gttattatga gatgccggtt ttaccgataa
     4921 accttgccaa caacaggcca agtgagagcg attatcaata cctcaggtga ttacactgca
     4981 ctcaacgatt cagcaaaaat ttaatgttgc ttttatgtga acgaattaac actgagttta
     5041 aatactggta tgctggcggg gcgaaactgg acgtcttacc ctacattgac tacatcagtg
     5101 ctgatggctg gtagcaatat acctaataga ttttaaggtg caggaaggca gcaagcgaga
     5161 gaggcttaat gagcttatac cagtaagtga tttgggtgat tgaacgcagc caacgcacat
     5221 gcagcttgaa gtcacttggg tatagatagc cgggtaaaat aaatgacaat aagagcgagg
     5281 agaaagtcgt gctagaagaa taccgtaagc acgtagccga gcgtgctgca gagggtatcg
     5341 tccccaagcc attagatgcg tcacaaatgg cagcgctggt tgaatcatta aaaaatccgc
     5401 ctgcgggcga agaagaattc ctattagacc tgctgactaa ccgtgttcca cctggtgttg
     5461 atgaagccgc ttacgttaaa gccggttttc tggctgctat cgccaaaggc gaagcccact
     5521 ccccactgat caccgcagag aaagcgattg agctgcttgg caccatgcaa ggcggttata
     5581 atatccaccc gctaattgat gcattggata atgagcaact ggcacctatc gcggcgaaag
     5641 cgttatccca cacgttgctg atgttcgata acttctacga cgtagaagat aaagccaaag
     5701 ctggcaatcc gtatgcaaaa caaatcatac aatcttgggc tgatgcggaa tggtatctat
     5761 cccgtccggc gttggcagaa aaactcaccg taaccgtatt taaagtgacg ggtgaaacca
     5821 acaccgatga tttatctcct gcccctgatg cgtggtcgcg cccggatatt ccattacatg
     5881 cgttggcaat gctgaagaac gcccgtgaag ggattcatcc agatcagccg gggagcgttg
     5941 gcccgataaa acagatcgaa gaactgaata aaaaaggttt tccactggct tatgtcggcg
     6001 atgttgtggg taccggttcc tcccgtaaat cggcgactaa ctccgtatta tggtttatgg
     6061 gtgacgacat tccttacgtg ccgaataagc gcggtggtgg tgtggttctg ggcagtaaaa
     6121 ttgccccaat cttctttaac accatggaag atgccggtgc gctgccaatc gaagtggatg
     6181 ttgccaaact gaatatgggc gacgtgatcg atatcttccc gtatcagggc gaagttcgtc
     6241 gccacgatac cggtgaagta ttagccacct ttgaattgaa aactgatgtg ctgttggatg
     6301 aagtccgtgc cggtggacgt attccgctga tcgttggtcg tggcttgacc accaaagccc
     6361 gcgagtcact gggcctgcct gtcagcgatg tgttccgtgt gccaaagccg gtagccaaaa
     6421 gtaacaaagg tttctcactg gcgcagaaaa tggttggccg tgcttgtggc gtcgcaggtg
     6481 tgcgccctgg tgaatactgc gaacctaaaa tgacgtcggt cggctcacag gatactaccg
     6541 ggccgatgac tcgcgatgag ctgaaagact tggcttgtct gggcttctct gccgatttag
     6601 tgatgcagtc attctgtcat actgcagcgt atcctaagcc agtagatgtg acgacccacc
     6661 acacattacc cgatttcatc atgaaccgtg gcggcgtgtc gctacgtccg ggcgatggca
     6721 tcattcactc ttggcttaac cgcatgctgt taccggacac tgtcggtacc ggcggtgact
     6781 cccatacccg tttccctatt gggatctcct tcccggcggg ttctggttta gtggcctttg
     6841 cggcagcgac cggcgtcatg ccattggata tgcctgaatc tgtattggta cgctttaaag
     6901 gtgaaatgca accggggatc accttgcgtg atctggttca tgctatccct tactatgcga
     6961 tccaagaagg cttgctgacg gttgagaaga aaggtaagaa aaacatcttc tcaggccgga
     7021 ttctggaaat tgaaggtcta ccagagctga aagtcgaaca agctttcgag ttggcagatg
     7081 cctctgctga acgttctgca gctggttgta ccatcaagct ggataaagcg ccgattaccg
     7141 aatacctgca atccaacgtt gttttgctga agtggatgat tgcagaaggc tacggtgatc
     7201 gtcgcacact agagcgccgt atcaatggga tggaaagctg gctggcgaac ccgagtctgc
     7261 tggaaggcga tgccgatgct gaatacgcag cggtgattga aatcgatctg gctgagatca
     7321 cacagcctat tttgtgtgca ccaaacgatc cggatgatgc tcgcttgttg tctgatgtgg
     7381 ctaacagcaa aatcgacgaa gtctttatcg gttcctgtat gaccaacatt ggccacttcc
     7441 gtgccgccgg taagttactg gatcagcata aaggccaact gcccacccgc ctgtgggtgg
     7501 caccaccgac caagatggat gcagcacagc tgacagaaga gggctattac agcgtctttg
     7561 gtaagagcgg tgctcgtatt gaaatccccg gctgttcact gtgcatgggt aaccaggcgc
     7621 gggttgctga cggtgcgacg gtggtatcca cctcaacccg taacttcccg aaccgtttag
     7681 ggaccggggc gaatgtgtat ctggcatcgg ctgagttggc ggcgatagcg tctctgcttg
     7741 ggcgcttacc aacgcctgat gagtatcaga cttacatggc tcaggttgat aagaccgccg
     7801 aggatactta tcgttatctg aactttgatc agttaagcca atatacggat aaagctgacg
     7861 gtgtgatctt ccaaaccgcg gtgtaaggcg tagtcccctt tgtcagtgac gttgggtatc
     7921 tattcgcatc agctaaaacg gggggccatt ggcctcccgt ttctatttta aaaacggtgc
     7981 tgtatttttg ctattcggca attatgtttt agctatctgc cattattttt ttaactatta
     8041 gcattacgtt ttaacgatca cagcatgttt taacgatcgc attatgttgt aatgctcacg
     8101 atacttgtaa gcggtgtgag cttgcgccaa gccaggttgg caataatgtt tacactaata
     8161 gaaagagcat taggaggacc tgctatggat tatgaattct tgcgtgattt aaccgggcaa
     8221 gtactcgtta aattctccat ggggcatgaa gtgatcggcc attggctgaa tgaagagatc
     8281 aaaggtgatt tggtaaaact ggatcacatt gaaacggcgg ctgacggtgt cagagggagc
     8341 gagcgccagt ggcaactccc aggccatgaa tatacgttgt ggctggatgg tgaagaagtg
     8401 atggtgcgtg ccaatcaatt agatctcgac ggcgatgaga tggaagaagg catgaattat
     8461 tacgatgaag aaagcctctg tctatgcggt ttagaggact ttttgctggt gttgaaaggc
     8521 tatcgggctt ttattacaca ataatatcta cccaaataac gtggtgttgc aggtaggcag
     8581 taagagagtg gccccgatgg gcttagataa gtaagtgatt cgggtaagcg gacaccacta
     8641 acaaccctac ggcttcaagt acgaagggga tttcggctgg ctgaccagca tagcaacgaa
     8701 cctgctacaa ccatggcaac gccaggccag aaagccgcag aaggcaaggt attgagccac
     8761 acgctggcga tcaatattga taacaatggc gtgaaatagg atagggccgc gaccagtgtg
     8821 gcgttgcctt ttttcattgc gctatcccag cattggtagg ccctatccca gcattggtag
     8881 gccagtgcgg tattcgcgcc catgagtaac aattcaaata tggctcgtgg ggtaaagtgc
     8941 aatttgcccg gagtccacat aaagaacatc aaccacaggc acagggcgca ggcgattaaa
     9001 aacagtggca gcgcccctgg cccttggcta tataaccgta ctaagttgga gtagcccgcc
     9061 caggtgaatg ctgcaatcag cgccaggctg tacgccagcg ggttgctgct gatatttacg
     9121 gcgagcgttt taacgtccag cccttcacca ccactgacca cccaaataac accaaataga
     9181 gcgagagccg cccccggcca taaccaccaa cgggcgcgga gtttcagcaa cggtaccgcc
     9241 aatagcagcg ttaggctcgg ccataggtaa ttgattaagc ctatctccag tgtttgctgg
     9301 cgatcattag ccataccgat tgccagagcg aaggccacca tatacaccac aaacagtaaa
     9361 ccgcagccat acagataagc gggatgctgc ccacgtactc taggcttacc tgccactagc
     9421 cataccagaa tcccactgac actgtagata gccgatccgg caccgaatgg ccccagtgct
     9481 tcggccagcc cacgtgttaa ggcgacactc atgctccaca gtaaaatcgc aataatgcca
     9541 tacagggttg ggaggcggtt cattaggggg catcttcctt gtgcaatgct aaagggggga
     9601 agaatatcat cttcttatac ttgtcatact tcaagttgca ggggttatgt attcaatacg
     9661 ttgataaccc atcaaaagca actctcgcgt tcaataaaag tgccgatgat cctatcgtgc
     9721 atttctggtg attttgaata cccaagcgta ccacagccag tgctggtatt tgttgttgcc
     9781 agcaaacgac cacatctcaa catattgaat atttgacctg atgtgttagg gacgctggtg
     9841 cagaatgtca aacaggactg gctgaattgt atcgagagaa tggagtatac caaccctgaa
     9901 cgggtaatta cgacgagccg tttttaggtg atcgcctgaa cgatcacctt taattccgta
     9961 tcagttatac agaattattt agagcctagg ctgtaatgca tcacacttcc ggcacattgc
    10021 ggccatagta gatttcctgc atttctttgt ataacaggcg ggtaatctgt tccttttctt
    10081 ctgcgcttag ctcttccggc ttggcgttaa acagataatg ctttaaatcg aaatctttca
    10141 gcatcatctt ggtatggaag atattttcct gataaacatt cacatccatc atgtgataaa
    10201 gcgacttcat gtcatcggac ataaaatttt gaatggaatt gattttgtga tcgataaaat
    10261 gttttacccc attgatatct cgggtgaaac cccgtacccg gtaatccatg gtcacgatat
    10321 cggattcgag ctgatggatc aggtaattca gggccttcag cggagaaatc accccacagg
    10381 tagagacctc gatatcggca cggaaagtac ataaccccgc ttcagggtgg ctttctggat
    10441 aagtatgcac acagatatgg ctcttatcca ggtgggccac cacggcgctt ggcaatggac
    10501 cgggatgttc agaggtatca acatcgcgcg gatcaacggg ctcttcactg accaaaatgg
    10561 tgacgctggc accttgtgga tcgtaatcct gacgagcaat atttaaaata ttggcaccga
    10621 tgatcgagca ggtttcgctc aagatctcgg tcaagcgatt ggcattgtac tgttcgtcaa
    10681 tgtaggcgat atagccatcg cggtcgtctg cggtcttggc ataacaaata tcgtaaatac
    10741 aaaaactcag gcttttggtc aggttgttga agccgtgcag tttaagcttg gacaatttag
    10801 ttcacctcct tacaaatgaa tactcaacat ttatcccttt tttactcggc actactgcgt
    10861 tgctagcggc tcttattcac ttgaatcgac gccaatgact ttgggtatcg tcgttaaggc
    10921 atctagcaaa tactgtggta aagcaaagct gccgacatga atcgctgggt tatagtagcg
    10981 gcaggccaag ccagcttggg caaagcggtt ttgcaaggtg gcgagatcca actggcgcag
    11041 agccgggttc tgtgtcgccc aggcaaaggt cataataccg ccgtaatacg ttggaattgc
    11101 ggcctgataa aaactaacgt cactgaaata gtggctaagt ttgttatggc tattgacggc
    11161 ttcatcctgt tgtaggaaac agacgccgtt ttgtgcaacg aagatccccc cctcattcag
    11221 gctacgggcg catccctcat aaaatacaga ggtaaacagg ctttcgccag gaccgatagg
    11281 atcggtacag tcagaaatga tgacatcgaa tttttcagtg gtctgattaa cgaaattcac
    11341 accatcgtcg atgactagct tgaaacgagg atcgtcatac gcccccgcgc tatgattagg
    11401 caaatactgg cggcaaaatt ctacgacccc ggcgtcaatt tccaccatgg taatctgctc
    11461 aatattcttg tggcggctga cttctcgcag cattgcgcca tcgccaccgc cgatgatcag
    11521 cacttttttt gcttgcccgt gggccagcaa aggaacgtgt gtcatcattt cgtggtagat
    11581 aaactcatca cgctctgtcg tttgcaccac accatctaat gccattacgc ggcccaactc
    11641 tgggttttca aaaatcacca ggtcctgatg ctcggttttt tcgcggaaca atacattctc
    11701 aacagaaaag tactggccga agttggcatg taatgtttca taccatagtt ctttctgtga
    11761 catgttcggg gcttctcctt cgcagtaaca gccatgaaaa atggggggca atatcatagc
    11821 caactctgcc tgaggttgca cggtcaaatt tcaggcaaaa ggcgttaaag gtgggatggt
    11881 caattagcgt aggctaataa actcaaagag tcacgggcta gagacttaca ttttacaggg
    11941 gtaggaaggg cgataccacg tagatcgcga tagctgtctt cacctaatgc cttcatatta
    12001 aagctatcgt aattgtggag atcccaacga ttttgctgcg caaagtagac aatggctcgc
    12061 ttaatttcgt tgttagggag ctcctgataa ccacaatcat tttttagata aacgaaaaca
    12121 gcggtcagat cggcaagatc ttcagcttca gattcactta atgcaaagct ggcagatgag
    12181 aatccgcaca gagtaagcag cagcatgact aacgttgttc ttttcatagc aaaaataggt
    12241 ttatttattg ttcacagacg ttaccacaca gtgatgtcac aaactaaatt ttattgtatt
    12301 gagcgaaagc atagtgtgag tgattgcttc ttgaccttcc cctaagagga gggtttaagc
    12361 tcgtataccg tgttttttat gtgtcaacgg aatgcgtcaa cggacgactt gtgtgtcaat
    12421 gggcgacgtg tataccaaca gacggttttt atatccatat atccatgtgc tatgcaggta
    12481 tttacctacg gtcagcattt acccatgatc agcatttact tatcatcaag aagggagacg
    12541 accatgcatc gccgtgattt tcttaagtta acggccgctc ttggagctgc cacatcactg
    12601 cctttatgga gccgagcggc attggccgca gatttttccc cgttacccat tccccctctg
    12661 ctccaaccgg atgccaacgg taaaattaat ctgaatattc agacggggag tgtggtctgg
    12721 ttaccttcca ctgcgacgca aacctggggc tataacggta atttattggg tccagcgatt
    12781 cgtttgcagc ggggtaaagc ggtaaccatt gatatcacta atgctttacc ggaagcgacc
    12841 acagtacatt ggcatggttt ggagatcccc ggcgaggttg atggtggccc acaggcgttg
    12901 attcagccag gggcaaagcg tcaggttacc ttcgcggtgg agcaacccgc cgcaacgtgt
    12961 tggttccatc cgcacactca cagtaaaacg ggtcaccaag tggcgatggg gttaggcggg
    13021 ttagtcctga ttgatgacag cgacagtgag acgctgccgt tgccaaaaca gtggggcgtg
    13081 gacgatattc ccgtaatttt gcaggataag ttactcgata aacatgggca ggttgactat
    13141 cagcttgatg tgatgaccgc cgcagtcggc tggtttggtg accggatgct gactaacggc
    13201 gttccttatc cgcaacaaat tacgccacgt ggctgggtgc gattacggct acttaatggc
    13261 tgtaatgccc gttcgctgaa tctggcgctt agcgatggcc ggccaatgta tgtgattgcc
    13321 agcgacggcg gattattagc cgaacccgtt gtggtgcgtg agttaccgat attgatgggc
    13381 gaacgtttcg aagtgctggt ggatacccgc gatggtcagt ctctcgattt ggtcaccctg
    13441 cccgttacgc agatgggcat gaccttggcc ccgtttgatc agccgctgcc cgtgctacgg
    13501 atccaaccct cactggcgat cggcagtcag gttttgcccg agtctctcgt ggtgatcccg
    13561 gaattagccg atgtcactgg tgtgcaggag cgctggttcc aactgatgat ggatccaaag
    13621 ctcgatatgc tggggatgca ggccttagtg gcgcgttatg gcatgaaagc catggccggt
    13681 atgaatatga atcatggtga catgggggcg atggaccatg gcaatagacc agatatgagc
    13741 cagggcaaaa tgaaaggcat ggatcatggc acaatgaacg gtgcgccagc ctttaatttc
    13801 agtcacgcga ataggattaa cggtaaagct ttctcgatga ccgaacccgc gtttgacgcg
    13861 aagcagggca aatatgagaa atggaccatt tcaggtgaag gcgacatgat gctacatcca
    13921 ttccatgttc acggcacaca gttccgtatt ttaacggaga acggcaaacc gccagcagag
    13981 catcgccggg gatggaaaga catagtacgt gttgaaggcg cacgcagtga aatattggtg
    14041 cgctttaatt atctcgcccc tgcgagtacg ccttatatgg ctcactgcca cttattggaa
    14101 catgaagata ctggcatgat gctgggcttt accgtcagcg cctgagccac accccggtcg
    14161 gttgaccggg gtgtttttta taaaaccgcc atcaatgcat cccactgcgc atttttgtta
    14221 tactttgtct cccctaagct ggcagagcca ctggatgcct cctgatgtgt gttaagctat
    14281 gggcatcaat ctgtatcatt gaggccatcg gtatcggttt cccattgata taaaagttca
    14341 ttcatttaaa taggtatgtt ggctgtgagg cacactgtag aagtcatgat ttccgaacag
    14401 gaagtaaaaa cccgtatcgc cgaattaggc cgccaaatct ctgaacatta ccgcgacagt
    14461 ggcagtgata tggtgctggt ggggttactc cgtggctcat ttatgtttat ggctgattta
    14521 tgccgtgcca ttgatgtttc tcatgaagtc gattttatga cggcctccag ctacggcaac
    14581 ggtatgagca ccacccgcga tgtgaagatc ctgaaagatc tggatgaaga tatccgtggt
    14641 aaagatgtgc tgattgttga agatattatt gattccggta atacgctgag caaagtacgt
    14701 gaaattctgc aattgcgtgg cccaaaatca ctggctatct gtacgctgtt ggataaacct
    14761 gagcgccgtg aagtgcacgt tccggttgag tgggtgggtt tcaccattcc cgatgagttt
    14821 gttgtaggct acgggatcga ttatgcgcag cggtacaggc atcttccgta tgtaggtaag
    14881 gttgtcactt tagacgagtg atcgggctac tgcgcgttgc catgttgagt ttacgcagtg
    14941 ctcagagtcc tcacgtactg catgtacgct ccggttcttg cgcgctggga cgcttaattt
    15001 agcggaaggg ttttgtggga gagggcgcgt tttaacgtac cctcccagag cgacttaatg
    15061 gtcttcttta ttgttttgta ataactcagc cattgctttg cgatacacca tttccaggct
    15121 accaaggctg gtggctgaga cttctaaatc acgcagcagg ccattttcaa taccatatac
    15181 ccagccgtgg atcatggctt tttgcccgcg cttccaggct gaacgcacaa tggttgaatg
    15241 accaaggtta tacacttgct ctaccacgtt tatctgacac aacacattac tgcgttcttc
    15301 ttgtggcagt tcacccaaca atgaactgtg tttataccaa aggtcccgaa tgtgcagtaa
    15361 ccagttatcg ataagcccca tctcttcgcc tttgatggcc gcttcaacac caccacagcc
    15421 aaggtggcca cagataataa tgtgttctac ctgaagaaca tcaatagcgt attggacgac
    15481 cgataggcag ttaagatcgg tatggataac cagattggca acgttacggt gaacaaataa
    15541 ctcgcctgat ttcaatccag ttaactgctc tgcgggaacg cgactgtctg aacaaccaat
    15601 ccataagaag cgcggtttct gagattgtgc caagtgctca aaaaaaccgg gatcatcttt
    15661 acaaatggta tttgaccaag ttcgattgtt cgcgatgagc ttttctattt ctttcatcaa
    15721 tgtaaatagc ctgtagtgtt cgggttgcga tagaataata tacggcaagg attccgattt
    15781 tgaaatcgga acagtagttt cggtaataac gcgatattgt ctgcgtaata tcttctcggt
    15841 gcctgtttga ttttttatgt tacccgtaac gtccctcatg tggggagggt taaatacgtc
    15901 atgggtacgc aggaccacca agagccccat tgaataaggt tcctttttac ttatgacata
    15961 tgcactggaa ataacgcagt tgaccaaaac ctatatgggt ggcgttcagg cactgcgtgg
    16021 tatcgatctg cacgtagagg caggcgactt ttatgctctg ctcgggccga atggggcggg
    16081 gaaatccact accatcggta ttattagttc attagtgaat aaaacatccg gcaaggttca
    16141 ggtttttggc tacgatatcg ataacgatat tgtgaatgct aaacgtcagc tcgggttagt
    16201 gcctcaggaa tttaatttca acccgtttga gacggtgtta cagatagtga ttacccaggc
    16261 cgggtactac ggtgtgaccc ggcgagacgc gttagcgcgg gcagagaaat atctcagtca
    16321 gttagattta tggagcaaac gtgatgagcg tgcgatccgt ttatcgggtg gcatgaaacg
    16381 ccgtttgatg attgcacggg cgctgatgca tgaacctaaa ttactgattt tagatgaacc
    16441 tacggcgggt gtagatattg aattgcgtcg ctccatgtgg gggttcttga aagagctgaa
    16501 tgcgcagggc acgacgatta ttctgacgac gcactatctg gaagaagcgg aaatgctgtg
    16561 ccgcaacatt ggcattatcc aaaatgggga attggtggaa aataccacca tgaaacagct
    16621 actgagtaag ctggaatcag aaacttttat ttttgatctt ggggcgaaaa gcccactgcc
    16681 taaattggaa ggttatggat accgtctgac ggatacctcg acgttggaag tggatgttaa
    16741 gcgtgaacag ggcctgaata gtttattcag ccaactgaac gtacaggggg ttcaggtaca
    16801 aagtatgcgt aacaaggcca accgtctgga agagctgttt gtcactttgg ttaatggcca
    16861 cgagggagag aaagcatgac ccgcctgtat tggatagcct tgcagagtat ttggatcaaa
    16921 gagattacgc ggttcgcacg tatttggatt caaaccttgg tgccacctgt gattacgatg
    16981 tctctctatt ttgttatttt cggcaaccta attggtgccc ggattggcga tatggggggc
    17041 tttgattaca tgcagtttat cgtccctggc ttgattatga tggcggtgat cactaacgcc
    17101 tattctaacg tggcggcatc gttctatggg gcgaagtttc agcgcagtat cgaagagttg
    17161 ctggtagccc ctgtgcctac gcatattgtt attatcggtt atgtcggtgg tggggtggcg
    17221 cgcggcattt gtgtcggcat tctggtgacg attatctcgt tattcttcgt gccactgcat
    17281 gtccattcgt ggtcaatgat tgccttgacg ctgatactaa cggccatcct attctccctg
    17341 ggaggattgt tgaatgcagt ctttgccaag acatttgatg acatcagttt ggtgccgact
    17401 tttgtgctga cgccattgac ctatctggga ggggtatttt attcgttatc attattgcca
    17461 cctttctggc aggcagtctc gaagcttaac cctatcgtct atatgatcag cggtttccgt
    17521 tatgggttcc tcggtattac tgatgtctca ctggcctaca ccattggcgt tttagtggtg
    17581 tttatcgcgg tattctatgc gtgggcgtgg tatttgattg agcgtggaac cgggttacgt
    17641 acctaatcta ttcccttccc tttgtccttg gcgctacagc ggcgctcgtt tgctgacttg
    17701 ctgtaacacc aagggctttg caatgtgggt atataaataa atcgtgctgt tacctgataa
    17761 cccctttttc aaccccaagt ctctcgtgat atgctggcgc acactatttc cctttttcca
    17821 ttcagcgccg actgcgcata agtagaacaa acatgtggca taaaaacaga atagctattg
    17881 ggatgctact cagcattgtc atgtgggtaa taatgatacc gacaacccag gctgacctct
    17941 tgccaaatgt ggaggtcaca ccaccaaaat atatgatgac cgaacgcgat agcgaagttt
    18001 attcgttggt tggtgaacat gttattcccg tcggagaaat caaagaaggc cagttgattc
    18061 aggtgacgcc agttattgct gaatactatg agtttaagtt tggcaacggt accggtttta
    18121 ttgataaaga tgatttacgt gagattaata aagcacaaaa aaacaacgac atgttgggcg
    18181 atttaaataa gcccctaccg aatcaaaata tactgacgat gcgtgaggct aaggtttatt
    18241 tggctgcgga tgtgcgcagt gaacaatttg ctgttctggc cgagaactta cgttatccca
    18301 ttgttggaaa attgaaagat cgtttaagca atacttggta tcaggtcaat attggtgatc
    18361 gcttggggta tgtcagtagc gcagacgctg aaatagacaa cggtattccg atcctgactt
    18421 accatcacat gttgaagaac gaagaaaata aacgcttcct gaacacctca accaccacat
    18481 ctgatgtggc gttcagtaat caaatggctt acctcaaaca ggcgggctat gacactattt
    18541 ctctgtatca gctcgaaggc tatctgaata acaagattaa tctgcctgcg aaagttgtag
    18601 tgctgacatt tgatgatggt ttgaagtcag tgagtcgcta tgcttatcct attctgaaag
    18661 agaatggttt ccgcgccacg gcgtttatta tctcttcgcg tattaaacgg catccacaaa
    18721 aatggaatcc agattcatta cagtttatga gtattgctga actgaaagga attcaagatg
    18781 tgtttgatat acagtctcat acgcattttt tacaccgcac cgataataga caccatccca
    18841 tattattgag tcgctcttat cacaatatca tttttgattt tgaacgctca cgtcgggcat
    18901 tagcgcagtt caatccgcat gtgatttttc tgtcatatcc cttcgggggt tttaatcaaa
    18961 cagcggtcaa tgcggcgaag aatgccggtt ttcatttggc ggtgaccacg atgcaaggca
    19021 aggtcaagcc aggcgataat ccatataccc tgaaacggct ctatattctc cgtactgact
    19081 caataccgac catggcggag cgcatcgcca atcaacccgg cccggttgcg gtaaaaccgg
    19141 cacccgcagt gattgaaatg gattaacgat gttatggcat aagacgttta tggcataaaa
    19201 aggaagggtg ttttatttaa gcgcccgagg ttaatcgcat tattatggct atctagccag
    19261 tgatccgggg gagcgaacat cgctaacccc cgtagcttca ggtactgagg gggattaagc
    19321 gacctgaact ggcactgcct tagctttgcg ttgtagctga ttttcacctt caaaataagc
    19381 cactttaggg tggtgcaaac gggcagcagc atatgacatc tgtacataag aacagataat
    19441 gagcttatca ccgacacaag cgcagcgtgc tgcggcacca ttcacggaga taatccgcga
    19501 accacgctca gcagcaatcg cataggttga aaaacgctga ccgttatcaa cgttataaat
    19561 atcaatagct tcgtattcca gaataccggc ggcttccaga aaatcctgat cgatggcgca
    19621 ggagccttca tagtgcaaat ccgcttgagt gactttgacc cggtgcagtt tgccttgcaa
    19681 catagtgcgt atcataactc ttacctttga ccctgattaa atctcttacc agaccctata
    19741 atctactgat tcagggagcg gctcaatcat aaaaatagac ccagatagat ttcgcgctaa
    19801 gcgtcctgcg gcctaagact ttctgcaaaa aatgcccact cagttttgcc gattttatac
    19861 cacttgtcta tgattgatgc cctatctgta aattttcctt gttgcctctt catttcatta
    19921 cgtccacttc cacggtatcc gcgtctctca ctcaccaaaa ccgttgctca tcggcggtca
    19981 cgggttccga gcgaacccgt tatgggggaa tgctgttgat agtgactttt accttggcgt
    20041 tcctggttga ttttgggcca actcgcggct tgaggggaat gagcaaccgc ctgatcggta
    20101 aaatatcagt ggcgcaaatc aaccagttgg ttatcaatca gacgagcttt acccaaccag
    20161 gcggccatca aaatcaccgc ttgctggcta tcgacagtca gtggctgtaa ggtctcggca
    20221 tcgcggataa acaattcatc gggcgtaaag cctacacgga gtagctgcgc tgccgcctct
    20281 tccaacagtg cgtcaatctg ccgttcgcct aaggccattt tctctgccag cgcccacatg
    20341 atcttactga gctgtggcgc aatctgacgt tcttcttccg tcagatagcc gttacgggaa
    20401 ctcagcgcca aaccatcttt cgcgcgcacc gttggtaccc caacaatgtt gatgtcataa
    20461 cccatatccg ccaccatttt gcggatcaag gcgagctgct ggtaatcttt ttcgccgaaa
    20521 caggcgacat ctggctggat cagattaaac agcttgctga cgatggttga aacaccgcgg
    20581 aaatgaccag ggcggctggc cccttctaaa atggtcgata gggcaggaac atcaacatac
    20641 gtttgctttt ccagccccgc agggtagata tcggctgcgg ccggtgcgaa caccagatct
    20701 gcaccgtggc gggtcagttt ctcgcaatct tcctgtaagg tgcgcgggta atgggctaag
    20761 tcatctggcc gttcaaattg cagcggatta acaaaaatag tcaccacgac cacgtcagcg
    20821 cgggtttttg cttcatccac cagcgtcata tgcccttcgt gcaggttacc catggtgggt
    20881 actaaggcaa ttcgtttgcc ttcctgacgc caacggcgga tctgttgacg tagcaatggc
    20941 aatgtctcaa taatcagcat tccctttctc ctgttttagg aacgatctat tttaggagga
    21001 tcctattttg aaaactccct attttagaag aaatattagt ggctcagtta ctggaatgta
    21061 tgctcttcag caggataaat ccccccctca acttcttcaa tatagagctt aatggcggca
    21121 cgaatatcgc ccgcactgtg tgctaaaaag tttttactga attttggcgt atgacccccg
    21181 gtaataccga gtgcatcatg cataaccaaa atctgaccgt cagtgacatt ccccgcacca
    21241 ataccaataa ccggtatggt taactcttcg gtcacccgct gtgccagttc taccggcacg
    21301 cattccagta ccaacagttg agcccctgcc tgttccaggg caatagcatc ttgcaacagt
    21361 tgattggccg ccacttcttc acgaccctgt actttatagc cgccgaaaat attcaccgat
    21421 tgtggcgtga gccccagatg cccacaaacc ggcaccgcgc gctctgccaa catgcgaatg
    21481 gtatcgcaca gccagctccc accttccagt ttgaccatat tggctccggc ccgcattagc
    21541 tctgccgcgt gggtaaaggc cagttctggc gtggcataac tcatgaatgg catatcggcc
    21601 aataacaggc aatgaggcgc accacggcgc actgcacggg tatggtaggc catatcggca
    21661 acggtcactg gcagcgtgga atcgaaccct tgtaacgtca taccgagcga atcccccacc
    21721 aatagcacct gaataccctg ttcggcaaat aactgggcaa aac
//
