LOCUS       NZ_GL882602.1          15103 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_GL882602.1 Bacteroides fluxus YIT 12057 Scfld0, whole genome
            shotgun sequence.
ACCESSION   NZ_GL882602
VERSION     NZ_GL882602.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-14 00:49:27
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 4838
            Orig. end    :: 19941
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15103
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[14838:19434]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14596
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..15103
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15103
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             778..1863
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GCV_T"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GCV_T_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_5"
                     /sec_met_domain="GCV_T (E-value: 3.6e-96, bitscore: 311.7,
                     seeds: 72, tool: rule-based-clusters)"
                     /sec_met_domain="GCV_T_C (E-value: 3.4e-25, bitscore: 78.2,
                     seeds: 348, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTTPFTEKHISLGAKMHEFAGYNMPIEYSGIIDEHLTVCQGVGV
                     FDVSHMGEFWVKGPKALDFLQKVTSNNVAALTPGKVQYTCFPNEDGGIVDDLLVYHYEP
                     EKYLLVVNASNIEKDWNWCVSHNTEGAELENASDRMAQLAVQGPKAILALQKLTSIDLS
                     ALPYYTFTHGEFAGEKDVIISNTGYTGAGGFELYFYPEVAMKIWDAVFEAGAEFGIKPI
                     GLGARDTLRLEMGFCLYGNDLDDTTSPIEAGLGWITKFVDGKNFTNRPMLEKQKTEGTI
                     RKLVGFEMVDRGIPRHGYELYSADGTAIGSVTSGTMSPVRKIGIGMGYVKPEFSKPGTE
                     ICIDMRGRKLKAVVVKPPFRK"
     CDS             complement(1984..3504)
                     /locus_tag="ctg1_6"
                     /transl_table=11
                     /translation="MKRLVTLFILTTLVIAAGFAKPRQKDLSGSIAIKGELTREYKKVP
                     AGTPVIIRRVVKTNQTTNNSGIYYAVEINGLQESVPLEEMDVVSLSTPETDREFWQQVY
                     LKRHLYEYFHNRGYKHKLRQEIDEECTDYLDKLNEIAYQDDYITSYVQSVFAKLNATTI
                     DPNRGESLNVRVIQSAEPDAFMLPNGSMLISTGLICTLDSEDELAAIIANELSHYVLDH
                     QVDNIYRAERRAKRAAFWGTVFAATAEAALDIAYWDDDRNAYAISFVADIAHITALLSM
                     PTIDRLGMKYKIGQEVTSDRLARELLTFKGYNPDGLASALEKILGYYNQHQRKEDINRY
                     GSIENLSKRLDKIGKAETQSNRPYLRNTCDVVTFNAAMNFANKRYKEAAQLIRKNISNG
                     FATDNDYIILVKAEMALSNSEEVNNRCLSLLDKAQEMAGENPNLDIYKQRVLLLMRMNK
                     QAKAADTLKEYLTLLTRYQEQGVEGEEKEWTNKEIGWANQMLERVSRI"
     CDS             complement(3658..3909)
                     /locus_tag="ctg1_7"
                     /transl_table=11
                     /translation="MKKGIHPENYRPVVFKDMSNGDVFLSRSTCNTKETIEFEGETYPL
                     VKLEISSTSHPFYTGKSKLVDTAGRVDKFMSRYGNRKK"
     CDS             complement(3924..4028)
                     /locus_tag="ctg1_8"
                     /transl_table=11
                     /translation="MKHFFYFREMHYLCALKKKTITLFNTKIVTEIIN"
     CDS             4090..5103
                     /locus_tag="ctg1_9"
                     /transl_table=11
                     /translation="MKKLFILFSFWLCIATLGAQNTERELYSVAFYNLENLFDTIHDAG
                     KNDYEFLPDGSYHWTAKKYEAKLQNLSRVLGALSKELVPEGPAFIGVAEVENRNVLVDL
                     VKQPAISKYEFVHYEGPDKRGIDCALLYDPDQFRVTASKLVLSTPFEGDTVHLTRGFLI
                     VDGELAGERVCVIVNHWPSRGAKTPVRVHAARQVKALKDSLMCQDKKLKLIVMGDMNDD
                     PMDESMKELGARKYIKEVKKGEFYNPWWETLEDKGVGTLLYRGKWNLFDQIVISKPLLK
                     AKRGLRYDHNEVFIRDYLIQQDGKYKGSPLRTHGGRTWLNGYSDHLPTILYLKKRN"
     CDS             5349..6350
                     /locus_tag="ctg1_10"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTKEMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCAHPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYEENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSAEHHT
                     YTDPEEVIDFATRTGCDSLAISIGTSHGAYKFTPEQCTVDPVTGHMVPPPLAFEVLDAV
                     MEKLPGFPIVLHGSSSVPQEEVETINKYGGALKAAIGIPEEWLRQAAKSAVCKINIDSD
                     SRLAMTAAIRKTFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGSDNKLA"
     CDS             complement(6524..8374)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_11"
                     /sec_met_domain="Alpha-amylase (E-value: 7.2e-63, bitscore:
                     203.3, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIFSILGAIMLSLSTYAAMNVNKIDPPFWYTGMQNPELQLMVY
                     GEGIGNASVSVNYPGVSLSSTVKLESNNYLLVYLKLDKNVKPGKMTLTFTEGKKKLVKE
                     YELKARAMKGCEHKGFDASDALYLLMPDRFANGNPDNDQIAGMAEYKVDRNDPNARHGG
                     DLAGIGQHLDYFSDLGVTALWFTPVLENNMTGGSYHGYATTDYYKVDPRFGTNEEYKQL
                     IEKSHARGIKIVMDMIFNHCGVEHVWIKDMPSKDWFNNPDHEKNFVQTSFKLTPHIDPY
                     TSQYDFDQMNDGWFVTAMPDLNQKNPHVYRYLVQNSFWWIEYANIDGIRMDTYPYADYD
                     AMSNWMKELNEEYPNYNTVGETWVVEPAYTAWWQKDSKLSAPKNSNLKTVMDFSFFDKI
                     NTAKTEQTETWFKGLDRVYNSFVYDFLYPNPASVLAFIENHDTDRFLGEGDNLPMLKQA
                     STLLLTTRRIPQLYYGTEIMMNGVKSKSDGYVRKDFPGGWPGDKETALTAEGRNKIQND
                     CYNFYKTILNWRKGNDVIAKGSMTQFMVQNGVYAYARQYEGKTVFVMLNGTDSETTVPL
                     KFYKEILKDSKSGKDVLSGKLISFGEELKMSPRESLVIEL"
     CDS             complement(8495..9823)
                     /locus_tag="ctg1_12"
                     /transl_table=11
                     /translation="MRKLIISLCLSACCSLLAAQNTNPIQEAMANYDYETALSLIEQEI
                     PTVPLLFQKGKALKGLGDNGKALLVFQEIAMQDSLNPRAYIEAAECCKSLAKYWEALTY
                     YQNALKLNPDNKYVRLQYISMLMSMKRYNESLQESNALAEKDSSAFVLHLRAESMGHVY
                     DNTQIMQVIEAYQDIQRRYPEDYLSAAKLGNIYVAGGQFEDAIETTEKYRAIDSTNILV
                     NRVNAQAYCLDKNYTKAIQRYEQLLQEKDSSFQTCFYAGISYYAIEDFYPAHDLLERAL
                     KDDGTNINVLYYLGRACSKTSWKKEGVMHLENAVKIAMPSDSIMTRLYVGLADCYKMAN
                     MHKEQANAILEQYKEYDRNKHKLLYDAAFIYYYRLKNISKAEQCLEAYLNTRPKEKQEQ
                     EVDGDGIPIIGENNRYNAAETWLNDIRKKRKEEKFFKGEIEKE"
     CDS             complement(10001..11161)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_13"
                     /sec_met_domain="OAD_beta (E-value: 4.1e-153, bitscore:
                     499.6, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEFITFLGNNLADFWTYTGFANATAGHVVMLLVGLFFIYLAVAK
                     EFEPMLLIPIGFGMLIGNIPFNMEAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLVGAAAQFGIFGAYMTALAIGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRLLTSKNERLIRMKPPRVVSHTEKVMFP
                     IIGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDTITILLGLTVGAS
                     TQASEFLSTDSLWIFGLGAFSFVVATASGVIFVKIFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             complement(11163..11603)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 65.5; E-value:
                     1e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_14"
                     /sec_met_domain="Biotin_lipoyl (E-value: 2.9e-21, bitscore:
                     65.5, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNVYKVAIGDIEDNIAHVEVNGTSYKVEMEKKPKAE
                     PIKPVVRPVASSAPAAAPAATVNRPAAASAGKSGVKSPLPGVILDIKVNVGDSVKKGQL
                     IVILEAMKMENSINADRDGKITAINVNKGDSVLEGTDLVIIE"
     CDS             complement(11628..12560)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_15"
                     /sec_met_domain="OAD_gamma (E-value: 1.8e-16, bitscore:
                     50.9, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLMLVLGFCSSCGDRKSNTKLLLNEVLIDNQSNFQ
                     DDYGVHSAWIEIFNRSYGSADLAGCYLKFSSQPGDTLSYFIPKGDVLTLVKPRQHALFW
                     ADGEPNRGTFHTNFKLDTSNANWIGLYDSGKKLLDQIVVPAGTLKANQSYARISDAADQ
                     WEVKGQSSDKYVTPSTNNKTIDSNAKMEKFEEHDSAGIGMAISAMSVVFCGLILLYISF
                     KVVGKISVNLSKRNAMRAKGITDKQEAKEKQLGQAPGEVFAAIAMAMHEFQSDVHDVED
                     TVLTITRVKRSYSPWSSKIYTLRETPHKK"
     CDS             complement(12575..14128)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_16"
                     /sec_met_domain="CT_Btheta (E-value: 7.2e-291, bitscore:
                     955.0, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIDRRAAARLGGGEKAIAKQHEKGKYTARERIAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYIFAQDFTVSAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAQTEEEGLALIRKLLGYIPQNNLEEAPYVDCTDPIDRLEDSLNEIIPDNPN
                     KPYDMYEVIGAIVDNGEFLEIQKDYSKNIIIGFARFNGQSVGIVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKDQENPAQFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRIIRALQQLQTKKLSNPAKKHGNIPL
                     "
     CDS             complement(14183..14596)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_17"
                     /sec_met_domain="Glyoxalase_4 (E-value: 2.9e-26, bitscore:
                     82.2, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGDVKIELLEPTSPESTIAKFIEKNNGNGGMHHLAFAVEDGVANALATVEAQGIRL
                     IDKAPRKGAEGLNIAFLHPKSTLGVLTELCEKP"
     CDS             complement(14777..14974)
                     /locus_tag="ctg1_18"
                     /transl_table=11
                     /translation="MIIIKLIQVFVTKPEQISVLANHLPSLAYTVAVTPQMPMNREMQD
                     KSDGVTAKYEKTPCSAEFNF"
ORIGIN
        1 tcaagcatgg caaaatccgc gtaggattta atccggatga agaaatcggt ctgggggctc
       61 ataagttcga tgtagaacgg tttggctgtg actgggctta taccatggat ggcggtgagg
      121 tcggtgaact tgaatttgag aatttcaatg cagcttccgc caaaattacc tttaaggggc
      181 gcaatgtgca tccgggttac gccaagcata agatgataaa ttccatgcgt gtagccaatc
      241 gttttatttc tatgttgccc agtcatgaaa ctccggaaca taccgaaggg tatgagggct
      301 tctatcattt gatcagtatc aacggtgagg tagagcagac tgctgtttcc tatattatcc
      361 gtgaccacga ccgtgcccgt tttgaaagcc gcaagaaaga aatggagcat cttgtcagaa
      421 agattaatac tgaatatggt gagggaactg ccactcttga acttcgggat caatactaca
      481 atatgcgtga gcagattgag ccggtgatgc atattatcga cactgcgttt gctgcaatga
      541 aagctgccgg tgttgaacct catgtaaagg ctatccgtgg tggtacggac ggtgcacagc
      601 tttcttttaa aggcctgcct tgtcccaata tctttgccgg ggggctgaac ttccacgggc
      661 gttatgagtt tgtgcccatc cagagcatgg agaaggctat gaacgtcatc gtgaaaattg
      721 cggaacttgt tgcttgtaaa taacatctaa tttataattc ataatttaaa atctaccatg
      781 aaaaccactc cgtttacaga aaaacatatc tcgctgggtg ccaaaatgca tgaatttgcg
      841 ggatataata tgcctattga atattctggc atcattgatg aacatctgac cgtttgccaa
      901 ggcgtcggtg tctttgacgt gtcacacatg ggcgagtttt gggtaaaggg tccgaaggct
      961 ttggactttt tgcagaaagt gacttccaat aatgttgccg cccttactcc gggcaaggtg
     1021 caatatactt gtttccccaa cgaggacggt ggtattgtgg atgaccttct ggtgtatcat
     1081 tatgaaccgg aaaaatatct ccttgtggtg aacgcttcca atattgagaa ggattggaat
     1141 tggtgtgttt cccacaatac ggagggtgcc gagctggaga atgcttccga ccgtatggca
     1201 cagcttgccg tgcaaggtcc aaaagccatt cttgctttgc agaaactgac ttctattgac
     1261 ctctctgcgc ttccttatta tacatttact catggtgaat ttgccggaga aaaggatgtc
     1321 atcatctcga ataccggtta tacaggtgca gggggatttg aactttattt ctatccggaa
     1381 gtagccatga agatatggga tgctgtattc gaggctgggg cggagtttgg tatcaagccc
     1441 atcggcttgg gagcccgcga tacgcttcgt ctggaaatgg gattctgttt gtacggtaat
     1501 gacttggatg ataccacgtc gcctattgag gccggtttgg gatggattac caagtttgta
     1561 gatggcaaga attttacgaa ccgtccgatg cttgagaaac agaaaacgga agggacaatc
     1621 cgcaaactgg ttggttttga gatggtggac cgtggaattc cccgtcacgg ttatgaattg
     1681 tatagtgcag acggtacggc tattgggtcg gtgacttcag gtacgatgtc acctgtccgt
     1741 aaaataggaa tcggtatggg atatgtgaag ccggaattca gtaagccggg tacggaaatc
     1801 tgtatagata tgcgtgggcg caagttgaaa gctgtagtgg taaaaccacc cttccgcaag
     1861 taacctggtt cagtgctttg cgccaaaaat agaagagtga aagaatgaaa agaacatcat
     1921 atcacggatg taaccttttc attctttcac tcttttattt ttaagctcat gtcttgtgcg
     1981 actttatatc ctgcttaccc tttccaacat ctgattggcc cagccaatct ctttattggt
     2041 ccattctttt tcttctcctt ccaccccttg ttcttgatag cgggtaagta gggtgagata
     2101 ttcttttagg gtatcggcgg ctttagcttg cttgttcata cgcattagca acaggaccct
     2161 ttgcttgtag atgtctaaat taggattttc accggccatt tcctgagctt tatcaagcag
     2221 ggaaaggcat ctgttgttga cctcttcaga gttggatagt gccatttctg cctttaccag
     2281 tataatgtag tcattgtctg tggcaaatcc gttgcttatg ttcttgcgta tcaattgggc
     2341 agcttctttg taacgcttgt tggcaaagtt catggcagcg ttgaaagtga ccacatcgca
     2401 agtattcctc aaatagggac ggttgctttg agtttccgct ttgcctattt tgtctaggcg
     2461 ttttgacaga ttctctatgc ttccatatcg gttgatgtcc tctttacgtt gatgttggtt
     2521 atagtaaccg aggattttct ccaaagcaga tgccagtccg tcaggattat atcctttgaa
     2581 tgttaacagt tcgcgggcca gccggtctga tgttacttct tgcccgattt tgtatttcat
     2641 acccagtcgg tctatggtag gcatgcttaa taaggcagtg atgtgggcga tgtcggcaac
     2701 gaaactgatt gcataggcgt tcctgtcatc atcccaataa gcaatgtcaa gagccgcttc
     2761 ggctgtagct gcaaatacag ttccccagaa ggcggcacgt ttggcgcgtc gttcggcacg
     2821 ataaatatta tccacttggt ggtcaagtac atagtgggat agctcgtttg cgatgattgc
     2881 ggcaagctca tcttcggagt caagtgtaca aataagtccg gtgctgataa gcatggaacc
     2941 gtttggaagc atgaacgcat ccggttcggc ggattggatg acacgtacgt tgaggctctc
     3001 gccgcgatta gggtcaatag tggtagcgtt tagtttggcg aatacacttt gtacataaga
     3061 ggtgatgtaa tcatcttgat aggctatctc atttaactta tccaggtagt cggtacattc
     3121 ttcatcaatt tcttgacgta acttgtgttt ataaccacga ttgtggaagt attcataaag
     3181 atgccttttg agatatactt gttgccagaa ctcccggtcg gtttccgggg tggagagaga
     3241 gacgacatcc atttcttcta aaggaacact ttcctgcagg ccgttgattt cgacggcata
     3301 atagattccg ctgttattgg tggtctggtt cgtttttacc acgcggcgaa taatgacagg
     3361 agtacctgcc ggtacctttt tgtactctct ggttaactcg cctttgatgg cgatactgcc
     3421 gcttaaatct ttttgcctgg gtttggcaaa tcccgctgca atgacaagag ttgtcagaat
     3481 gaataaggtt accagtcgtt tcatatttat tggagtttat tattgtcatg ctacaaaaat
     3541 aggaaagagt ttcctttctt gcttgttttt tcccctattt gccaatagga aaaaccctat
     3601 aaaaaaaggg aatcttcata aaaaagattc ccttcctcca gtactttgaa tactgaatta
     3661 tttcttgcgg ttaccgtaac ggctcatgaa cttgtcaacg cggccggcag tgtcaaccaa
     3721 tttggactta ccggtataga acgggtgaga agtgctggag atttccaact ttaccaacgg
     3781 ataagtttca ccttcgaatt cgatagtctc ttttgtgttg caagtagaac gagacaagaa
     3841 tacatcaccg tttgacatat ctttaaatac taccgggcgg taattttcag gatgaatacc
     3901 ttttttcatt tcaatatttg tttttaattt attatttcgg ttactatttt ggtattaaat
     3961 agtgtaatgg tcttcttttt cagagcgcaa agataatgca tttctctgaa atagaaaaaa
     4021 tgtttcatga aaaaataggt ttatcccgtt ttatttctga tttttgcatg gaattaatct
     4081 ctttaattta tgaaaaaact atttattcta ttctctttct ggctctgcat tgcgactttg
     4141 ggggcacaga atacagaacg ggagctgtat agcgttgcgt tctacaatct ggaaaatttg
     4201 tttgatacca ttcatgatgc gggcaagaac gattatgaat ttctgcctga cggaagctat
     4261 cattggacag ccaagaaata tgaggccaag ttgcagaatc tctctagggt tttaggggcc
     4321 ttgtcaaagg aactggtacc cgagggaccg gcttttatag gggttgccga agtggaaaac
     4381 cgtaatgtat tggtcgatct ggtaaagcag cctgccatct ccaagtatga atttgtacat
     4441 tatgaaggcc cagacaaacg tggaattgat tgtgcattgc tttatgatcc ggaccaattt
     4501 cgagtaaccg cttctaagtt ggtactttct acgccttttg aaggagatac ggtacatctg
     4561 acccggggat ttctgatagt agatggtgag ttggcaggtg aacgtgtctg tgtgatagtc
     4621 aatcactggc cgtcacgtgg tgccaagacg ccggtacgtg tacatgccgc cagacaggtg
     4681 aaagccttga aagactcctt gatgtgtcag gacaaaaaac tgaagctgat agtcatggga
     4741 gacatgaatg atgaccccat ggatgaaagt atgaaagaat tgggggcacg caagtatatc
     4801 aaagaggtaa agaagggtga gttttataac ccatggtggg aaaccttgga agataaagga
     4861 gtgggaaccc ttctatatcg gggaaaatgg aacttatttg accagattgt tatttcaaag
     4921 cctttgctaa aggcaaagag gggattgcgg tatgaccata atgaggtctt tatacgtgat
     4981 tatcttattc agcaagatgg caaatataaa ggttctccat tgcgtacaca cggtgggcgg
     5041 acttggctga acggttatag tgaccatttg ccgacgattc tctatttgaa gaaaagaaac
     5101 tgatagctgc cgtagtatat tttttaacag gattataagt agataagtcc gcaagggact
     5161 cttccttttt attcgttttt tgtaacatag agattacaat cctctgttaa atgaagcgaa
     5221 cagctatgaa atagaatgta tttcggcggg tgatgcggat attttattcc tgtcgagcct
     5281 tttactttaa aggataatgc ttacttttgc gtagaatttt tattcactaa caataaactt
     5341 taaacaaaat ggtaaattac aaagatttag gattggtaaa cacgaaagaa atgtttgcta
     5401 aggccatcaa aggtggatat gctattccgg cattcaactt caacaatatg gaacagatgc
     5461 aggctatcat caaggctgca gttgaaacta aatctcctgt gattcttcag gtttctaaag
     5521 gtgcccgtca gtatgccaat gctactttgt tgcgttatat ggctcagggt gctgtagaat
     5581 atgctaaaga attaggctgc gctcatccgg aaatcgttct tcaccttgat catggagata
     5641 cttttgaaac ttgcaagtct tgcattgatt ccggtttctc ttcagtgatg attgacggtt
     5701 ctcaccttcc atacgaagaa aatgttgctt tgactaagaa agtggtagaa tatgctcacc
     5761 agttcgatgt aactgtagaa ggtgaacttg gtgtattggc cggtgtagaa gacgaagttt
     5821 ctgccgaaca ccacacttac actgatcctg aagaagtgat tgacttcgct actcgcacag
     5881 gttgcgattc tttggctatc tcaatcggta cttctcacgg tgcttacaag tttactccgg
     5941 aacaatgtac tgttgaccct gttacaggcc acatggttcc tcctcccttg gcattcgaag
     6001 tattggatgc agttatggag aaacttccgg gattccctat cgttcttcac ggctcatctt
     6061 cagtacctca ggaagaagtt gagactatca acaagtatgg tggtgctttg aaggctgcta
     6121 tcggtattcc cgaggaatgg ttgcgtcagg ctgccaagtc tgctgtttgc aagattaaca
     6181 ttgactcaga ctctcgtttg gctatgactg ctgctatccg taagacattt gcagaaaaac
     6241 cggctgaatt cgatccgcgt aaatacttgg gtccggctcg tgacaacatg gagaaattgt
     6301 acaagcataa aatcatcaat gtgctgggat cagacaataa gttggcttaa taagagttag
     6361 actctgatat ataaaaagag gtgtgtcaaa attcacacct ctttttttat gcacaagaag
     6421 gtgcatcgtg cattacgaca cacctccatt ttttgcggtt tacacagcta actgcgttgg
     6481 cttacacata taagtgtgta ggccgacgca gttagatgtg tttttatagt tcgataacca
     6541 gtgattctct gggagacatt ttcagctctt cgccgaatga gatcagcttt ccactaagaa
     6601 catcttttcc gctttttgaa tctttcagta tttccttgta aaatttcaaa ggcactgttg
     6661 tttcagagtc tgttccgttc agcatcacga atactgtttt gccttcgtat tggcgtgcat
     6721 aagcatatac gccattctgc accataaact gagtcatgct tcctttggca atgacatcgt
     6781 ttccttttcg ccagttcaat atggttttgt agaagttgta gcagtcattc tggattttgt
     6841 tgcgtccttc ggctgtaagg gcagtttctt tgtcgccggg ccagccgccg gggaagtctt
     6901 tgcggacata accgtcactt ttgcttttca caccgttcat catgatttct gttccgtagt
     6961 acagttgcgg aatgcggcgg gtagtaagca gcagggtaga ggcttgcttc agcatcggca
     7021 agttatctcc ttctcccaga aaacggtcgg tgtcatggtt ttcgatgaat gccaggacag
     7081 aggccgggtt gggataaagg aaatcatata caaaactatt atatacgcgg tccagacctt
     7141 taaaccaggt ttccgtttgc tcagtcttgg cagtgttgat tttgtcgaag aaactgaagt
     7201 ccattactgt tttcaggtta ctgttcttgg gagcagacag tttggagtct ttctgccacc
     7261 aggctgtata ggcaggctct actacccatg tttcacctac ggtgttgtag ttgggatact
     7321 cttcgttcag ttctttcatc cagttgctca tggcatcgta gtctgcataa gggtaggtat
     7381 ccatgcggat gccgtcgata ttggcatact cgatccacca gaagctgttt tgaaccaggt
     7441 agcggtaaac gtgcggattc ttttggttga gatccggcat ggcggttaca aaccaaccgt
     7501 cattcatctg gtcgaagtca tattgggagg tataaggatc aatgtgcgga gttagtttga
     7561 aagaagtctg gacaaagttt ttctcatggt cgggattatt gaaccaatct ttagaaggca
     7621 tatctttgat ccatacatgt tctacgccac aatggttgaa aatcatatcc attacaatct
     7681 tgataccgcg tgcatgggat ttttcaatca gttgtttgta ttcctcattg gtaccgaagc
     7741 ggggatccac cttgtaataa tcggtagtgg catatccgtg ataggaaccg ccggtcatgt
     7801 tgttttccaa taccggggta aaccaaaggg cggtaacacc gaggtcggaa aagtagtcga
     7861 ggtgttgtcc gatgccggct aagtcaccgc cgtgacgggc attgggatcg ttacgatcta
     7921 ctttgtattc agccattccg gcaatctggt cattgtcggg attgccattg gcaaagcggt
     7981 cgggcattaa cagatacagt gcgtcggatg cgtcaaaacc tttgtgctca caacctttca
     8041 tggcacgggc tttcaactca tattccttaa cgagtttttt cttgccttcg gtgaaggtta
     8101 aggtcatttt gcccggtttc acgtttttat ccagtttaag ataaaccagc agatagttgt
     8161 tactttccag tttgactgtg ctgcttaatg aaacgccggg gtaattgacc gatacggatg
     8221 cgttaccgat gccttcgcca tataccatta gttgaagttc aggattttgc attccggtgt
     8281 accagaaggg aggatcgatt ttgttcacat tcatcgctgc atacgtgcta agtgagagca
     8341 tgattgctcc tagaatagag aaaatttttt tcatgatagt aacttttcgg ttattttatg
     8401 tgtgctaatt taaaacaatt agcggagaaa caaaccgttt ccccgccgac tataccttat
     8461 tatattatgc aaacgttttc tgtaaccgga taaattattc tttttctatc tcgcctttga
     8521 agaatttttc ttcttttctt ttttttctga tatcgttcag ccatgtttcg gcggcgttat
     8581 acctgttgtt ttccccgatg atgggaatac cgtctccgtc cacttcttgt tcttgctttt
     8641 ctttggggcg ggtgttcagg taggcttcca gacattgttc ggctttggag atgttcttca
     8701 gacgataata gtagatgaaa gcggcatcat aaagtagctt atgtttgttc cggtcatatt
     8761 ctttgtattg ttccagaata gcatttgcct gctctttgtg catgtttgcc attttgtagc
     8821 aatccgctaa tcctacgtat aggcgtgtca tgatactgtc actgggcatg gctatcttaa
     8881 cagcattttc cagatgcatt acgccttcct ttttccatga ggtcttggag caggcacgtc
     8941 ccaggtaata gagtacgttg atattggtac cgtcatcctt gagcgctctt tccagcaagt
     9001 catgtgccgg gtaaaagtct tcgatggcat agtagctgat tcctgcataa aagcaggtct
     9061 ggaagctgct gtccttttcc tgcagcagtt gttcgtatct ctgtatggct tttgtatagt
     9121 ttttgtccag acagtaagcc tgtgcattga cccggttgac aaggatgttg gtggaatcga
     9181 tggcgcgata tttttcagtc gtttctatgg catcctcaaa ttggcctccg gcaacataga
     9241 tattacccag tttggcggct gacagatagt cttcagggta tcttctctgt atgtcctgat
     9301 aagcttctat tacctgcatg atttgggtat tgtcgtaaac gtgtcccata ctttcagccc
     9361 tgagatgcag cacgaaggca gaactgtctt tctcggccaa tgcattgctt tcttgcaggg
     9421 attcgttgta tctcttcatg ctcatcaaca tactgatgta ttgcaggcgt acatatttat
     9481 tgtccggatt cagctttaat gcattttggt agtaagttag tgcttcccag tatttggcaa
     9541 gagacttgca gcattcggca gcctcaatat aggcacgcgg gttgagtgag tcctgcattg
     9601 cgatttcttg aaataccagt aacgctttgc cgttgtctcc caagcctttt aaggcttttc
     9661 ccttttggaa cagcaaaggg acagtaggta tttcctgttc aataagtgac aatgcggttt
     9721 cgtagtcata attggccatt gcttcttgaa taggattggt gttttgtgct gccaataagg
     9781 aacaacaagc actgagacat aaggaaataa taagttttct cataccgtat tagcttttat
     9841 ttctcgttaa actgagtgca agttactaaa aataccgtgt ttacgaaaat atcgtaattt
     9901 attttggata gattaacaaa aaagcccctt catatggaag gggcttttac aactggttga
     9961 aaacctgttc agtcagttgt atgtaacata tacattatat ttacattaag aatcctaaca
    10021 ggataccggc tgctacagca gaaccgatta cgcctgccac attcggaccc atagcatgca
    10081 tcaataagta attggtagga tcgtattcca gacctactac ttgggagata cgtgcagaat
    10141 cgggcacggc agatacaccg gcattaccga tcagcggatt aatcttattg cctttcttca
    10201 ggaagagatt gaatatcttc acgaagatta caccggaagc agttgcgacg acgaatgaga
    10261 atgcgcccag accgaaaatc cataatgagt ctgtgctcag gaactcggat gcttgcgtgg
    10321 aagcacctac ggtcagaccc agcaggatgg tgattgtatc aatcagcgga ccgctggccg
    10381 tgttggccag acgacgggtt acaccgcttt ccttcaacag gttaccgaag aacagcatac
    10441 ccagcaaagg caggccggac ggaacgagga agcaagtgag caacagaccg ataatcggga
    10501 acatcacttt ttccgtatga gaaacaacgc gcggcggttt catgcggata aggcgttcgt
    10561 tcttgctggt aagcagacgc atgatgggcg gctgtattac cggtaccaac gccatgtagg
    10621 aataggcgga caccgcgatt gcacccatca ggttgggagc cagcttggac gaaaggaaga
    10681 tagccgtcgg gccgtctgca ccaccgatga tgccgatagc tccggcttgc atcggatcga
    10741 atccgatggc taaggctgtc atgtatgcgc cgaaaatacc gaattgcgcg gctgcgccga
    10801 ccagcatcag cttcgggttc gaaatcaggg cggagaaatc cgtcatggca ccgataccca
    10861 ggaatatgag tggcggatac caaccggaag ttaccccttg atacaggatg ttgagtacag
    10921 aaccttcttc gtagataccg actttcaatc cggcttccat attaaaaggt atattaccga
    10981 tcagcatacc gaaaccgata ggtatcagaa gcatcggctc aaattccttg gctacggcca
    11041 agtatatgaa aaacaaacct accagaagca ttaccacatg tcctgccgtt gcattggcaa
    11101 aacccgtata tgtccagaag tcggcaaggt tgtttcctaa aaatgtgatg aattctccca
    11161 tattattcaa taattacgag gtcagtacct tcgagaaccg agtctccttt gttcacattg
    11221 atggctgtaa tcttgccgtc tctgtcggca ttgatgctgt tctccatttt catggcttcc
    11281 aggattacga taagttgtcc cttcttcacg ctgtcgccta cgttcacctt gatgtcgagg
    11341 atgacgccgg gaagcgggga ttttacgccg gacttgccgg cagaagctgc tgccgggcgg
    11401 ttgactgtag cagcgggcgc agcagcaggt gcggaacttg ctaccgggcg tactaccggc
    11461 tttatcggtt cggcttttgg cttcttctcc atttcaacct tgtaggaagt accgttcact
    11521 tctacgtgag cgatgttgtc ttcaatatct ccgatggcaa ctttatatac gttgccgtta
    11581 attttatatt tatattcttt catcgtttta gctttattat gggtgactta ctttttgtgg
    11641 ggagtctcac gcagcgtata gatctttgaa ctccaaggag aataactgcg ttttacgcgg
    11701 gtaatggtaa gtacggtatc ttccacatcg tgtacgtcgc tctggaattc gtgcatagcc
    11761 attgcgatag cggcgaatac ctctccggga gcttgtccca gttgtttctc tttcgcttcc
    11821 tgtttgtcgg tgatgccttt ggctctcatg gcattgcgct tgctgaggtt gacggatatt
    11881 ttacctacaa ccttgaatga gatataaagc agtatcaatc cgcagaaaac aacgctcatg
    11941 gcagatattg ccatacctat acctgcgctg tcatgctcct cgaacttttc cattttggca
    12001 ttgctgtcga tagtcttgtt gttggtgctt ggagtcacgt atttgtcgct gctctgtccc
    12061 ttcacttccc attggtctgc agcgtcactg atacgcgcat acgactggtt agccttcagt
    12121 gtaccggcag gcactacaat ctggtcaagc aatttcttcc cggaatcgta caggccgatc
    12181 cagttggcat ttgaggtatc cagtttgaaa tttgtgtgga aagtaccacg gttaggctct
    12241 ccatccgccc agaacaaggc atgctgacgg ggttttacca aagtcagaac atcgcctttg
    12301 ggaataaaat aactgagagt atcacccggt tgactactga acttcagata gcaacctgca
    12361 aggtcggcac taccgtatga tctgttgaat atttcaatcc atgcgctatg tacaccgtag
    12421 tcatcctgaa agttgctttg attgtcaatc agcacctcat tcagtaataa cttagtattt
    12481 gatttccggt ctccacaaga agagcagaag cctagtacca gcatcaatga aaggaatatt
    12541 ccgattttag ttttattcat aaattcaagt tttattagag tggaatatta ccatgcttct
    12601 tagccggatt acttaatttc ttagtttgca actgttgcag ggcacggatg atgcggaaac
    12661 gtgtattacg cggttcgatc acgtcatcga tgtaaccgta tttagctgca ttataaggat
    12721 tggcaaacag cttggtgtat tcggcttcct tttcggcgag gaattgggcc ggattttcct
    12781 ggtccttggc ttcacgggca tacaatacct ctacggcacc tgcaccaccc attacggcga
    12841 tttcggcggt aggccatgca tagttcatgt caccacggag ttgtttacag ctcatcacaa
    12901 tgtgagaacc gccgtaagac ttgcgcaggg taatggttac tttgggcacg gtagcctcac
    12961 cgtaggcata cagcaatttg gcgccgtgca gaattacgcc attgtattcc tgtcctgtgc
    13021 ccggcaggaa tcccggtaca tctaccaatg atacgatagg aatgttgaaa gcatcgcaga
    13081 agcggacaaa gcgtgcgcct ttacgggagg cgttgctgtc aagtacacct gccagatatt
    13141 tcggctggtt ggcaacgata cctacggatt gtccgttgaa acgtgcgaaa ccgatgatga
    13201 tattcttgga ataatctttc tggatttcaa ggaattcacc gttgtcaaca atggctccga
    13261 tgacttcata catgtcatac ggcttgttgg gattgtcggg aatgatctcg ttcagagaat
    13321 cttccagacg gtcaatcggg tctgtacaat ctacgtaagg agcctcttcc agattgtttt
    13381 gcgggatgta tcccaaaagc ttgcggataa gagccaaacc ttcttcttct gtctgggcgg
    13441 taaaatgagt gacacccgat ttggtagagt gaacgcttgc gccacccagg ttttcctggc
    13501 tgacgtcttc gccggtcacg gtcttcacca ctttcgggcc ggtgaggaac atataggaag
    13561 taccttccat catcaaagtg aagtccgtca aagcgggaga ataaacggca ccgccggcac
    13621 aagggccgaa gattccggaa atctgcggaa taacacctga agcaaggata ttgcgttgga
    13681 aaatttcagc atatccggcc aaagcgttga tgccttcctg gatgcgggcg ccacccgagt
    13741 cattgatacc gatacaggga gcacccatct tcatggcttg atccatgatc ttgcaaatct
    13801 tcaatgacat ggtttcagac aaagaaccgg cagaaaccgt aaagtcttgt gcaaagatat
    13861 aaaccagacg accttcgata gtaccgcaac cggtcactac accgtcaccg ggatagtgtt
    13921 tcttttccat gccgaagttg gtacatctgt gttcaacgaa catgtccatt tcctcgaaac
    13981 tgccttcgtc gagcagcatg gcaatgcgct cgcgagctgt atatttacct ttctcgtgtt
    14041 gcttggcaat ggctttctca ccaccaccga ggcgtgcagc ggcgcggcgg tcgataagct
    14101 ctttaatttt ctcaagttga ttactcatct ttttggattt atgatttata atttatgatt
    14161 tatggcttgg gaatttggag atttatggtt tctcgcaaag ttctgtcaat acgccgagtg
    14221 ttgatttcgg atgaaggaat gcgatgttca acccttctgc acctttacgg ggagctttgt
    14281 cgataaggcg tatgccttgt gcttccaccg tggcaagggc attagctact ccgtcttcaa
    14341 cagcgaatgc taaatggtgc atacctccat tgccattgtt cttttcgatg aatttggcaa
    14401 tggtactttc gggagaagtc ggttccagca attcgatttt tacatcgcca accttcagaa
    14461 aagctgttct tactttctga tcctccactg tctcaatgtt gtagcatttc aaacctaaaa
    14521 cgttttcata atacggaagg gcttcttcaa tgctcttgac ggcaatgccc agatgttcaa
    14581 tgtgtgaaat cttcataact atattaatta atattggtat tgaatccttt tttcaagcat
    14641 aaagcagtac aaagaaagat atttcttcta aaataaagaa atttttcgtc aattaattgt
    14701 ttgataaatg tagcggaaaa gtgtttatcc tgtcagatag ggggaagtat gacattgtaa
    14761 acacggcttc tttcatttaa aagttgaatt cagcgctaca gggagttttt tcatattttg
    14821 ccgtcactcc gtcacttttg tcctgcatct ctctgttcat cggcatttgc ggagtgacgg
    14881 caaccgtgta ggcaagtgac ggcaaatggt ttgccagcac gcttatttgt tctggttttg
    14941 ttacaaatac ttgtatcaac tttatgataa tcatcttttt ccctgtttgt ttattttgcg
    15001 ttttccattg tgtggaaata acttttatta acgtcggttt tagcccaatt tggcacttta
    15061 ctattcaaaa atctcttgtc tgatgactga ttcttgcatc cgg
//
