LOCUS       NC_004337.2            24598 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_004337.2 Shigella flexneri 2a str. 301 chromosome, complete
            genome.
ACCESSION   NC_004337
VERSION     NC_004337.2
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-03-13 23:39:45
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 4086633
            Orig. end    :: 4111231
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24598
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[4096633:4101231]"
                     /cutoff="10000"
                     /detection_rule="(Molybdopterin and Form-deh_trans and not
                     (Nitr_red_bet_C or Nitr_red_alph_N) and minimum(3,
                     [Fer4_11, Fer4_4, Molybdop_Fe4S4, Molydop_binding,
                     Ni_hydr_CYTB]))"
                     /neighbourhood="10000"
                     /product="Formate_dehydrogenase"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14598
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Molybdopterin and Form-deh_trans and not
                     (Nitr_red_bet_C or Nitr_red_alph_N) and minimum(3,
                     [Fer4_11, Fer4_4, Molybdop_Fe4S4, Molydop_binding,
                     Ni_hydr_CYTB]))"
                     /neighbourhood="10000"
                     /product="Formate_dehydrogenase"
                     /protocluster_number="1"
     cand_cluster    1..24598
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Molybdopterin and Form-deh_trans and not
                     (Nitr_red_bet_C or Nitr_red_alph_N) and minimum(3,
                     [Fer4_11, Fer4_4, Molybdop_Fe4S4, Molydop_binding,
                     Ni_hydr_CYTB]))"
                     /kind="single"
                     /product="Formate_dehydrogenase"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24598
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Formate_dehydrogenase"
                     /region_number="19"
                     /rules="(Molybdopterin and Form-deh_trans and not
                     (Nitr_red_bet_C or Nitr_red_alph_N) and minimum(3,
                     [Fer4_11, Fer4_4, Molybdop_Fe4S4, Molydop_binding,
                     Ni_hydr_CYTB]))"
                     /tool="gutsmash"
     CDS             680..1465
                     /locus_tag="ctg1_4227"
                     /transl_table=11
                     /translation="MSLTELTGNPRHDQLLMLIAERGYMNIDELANLLDVSTQTVRRDI
                     RKLSEQGLITRHHGGAGRASSVVNTAFEQREVSQTEKKKAIAEAVADYIPDGSTIFITI
                     GTTVEHVARALLNHNHLRIITNSLRVAHILYHNPRFEVMVPGGTLRSHNSGIIGPSAAS
                     FVADFRADYLVTSVGAIESDGALMEFDVNEANVVKTMMAHARNILLVADHTKYHASAAV
                     EIGNVAQVTALFTDELPPAALKSRLQDSQIEIILPQEDA"
     CDS             1564..2163
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4228"
                     /sec_met_domain="HAD_2 (E-value: 2.5e-13, bitscore: 48.6,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLYIFDLGNVIVDIDFNRVLGAWSDLTRIPLASLKKSFHMGEAFH
                     QHERGEISDEAFAEALCHEMALPLSYEQFSHGWQAVFVALRPEVIAIMHKLREQGHRVV
                     VLSNTNRLHTTFWPEEYPEIRDAADHIYLSQDLGMRKPEARIYQHVLQAEGFSPSDTVF
                     FDDNADNIEGANQLGITSILVKDKTTIPDYFAKVLC"
     CDS             2157..3029
                     /locus_tag="ctg1_4229"
                     /transl_table=11
                     /translation="MLKTIQDKARHRTRPLWAWLKLLWQRIDEDNMTTLAGNLAYVSLL
                     SLVPLVAVVFALFAAFPMFSDVSIQLRHFIFANFLPATGDVIQRYIEQFVANSNKMTAV
                     GACGLIVTALLLMYSIDSALNTIWRSKRARPKIYSFAVYWMILTLGPLLAGASLAISSY
                     LLPLRWASDLNTVIDNVLRIFPLLLSWISFWLLYSIVPTIRVPNRDAIVGAFVAALLFE
                     AGKKGFALYITMFPSYQLIYGVLAVIPILFVWVYWTWCIVLLGAEITVTLGEYRKLKQA
                     AEQEEDDEP"
     CDS             3026..3463
                     /locus_tag="ctg1_4230"
                     /transl_table=11
                     /translation="MIALIQRVTRASVTVEGEVTGEIGAGLLVLLGVEKDDDEQKANRL
                     CERVLGYRIFSDAEGKMNLNVQQAGGSVLVVSQFTLAADTERGMRPSFSKGASPDRAEA
                     LYDYFVERCRQQEMNTQTGRFAADMQVSLVNDGPVTFWLQV"
     CDS             3508..4449
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4231"
                     /sec_met_domain="Acetyltransf_1 (E-value: 4.5e-14,
                     bitscore: 50.8, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYHLQVPQTEEELERYYHFRWEMLRKPLHQPKGSERDAWDAMAHH
                     QMVVDEQGNLVAVGRLYINADNEASIRFMVVHPDVQDKGLGTLMAMTLESVARQEGVKR
                     VTCSAREDAVEFFAKLGFVNQGEITTPTTTPIRHFLMIKPVATLDDILHRGDWCAQLQQ
                     AWYEHIPLSEKMGVRIQQYTGQKFITTMPETGNQNPHHTLFAGSLFSLATLTGWGLIWL
                     MLRERHLGGTIILADAHIRYSKPISGKPHAVADLGALSGDLDRLARGRKARVQMQVEIF
                     GDETPGAVFEGTYIVLPAKPFGPYEEGGNEEE"
     CDS             4865..5056
                     /locus_tag="ctg1_4232"
                     /transl_table=11
                     /translation="MVANINLIKQESYSVVNLEKQLMSNKSPKQTLLNQFSGNDSNLLI
                     VFYVQIMPDDLVMQLHRF"
     CDS             complement(4991..5494)
                     /locus_tag="ctg1_4233"
                     /transl_table=11
                     /translation="MSRQCTHYGRWPQHGFTSLKKLRPQSVTSRIQPGSDVIVCAEMDE
                     HWGYVGAKSRQRWLFYAYDRIRRTVVAHVFGERTLATLERLLSLLSAFEVVVWMTDGWP
                     LYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLVRKSLSFSKSVELHDKVIGHYLNI
                     KHYQ"
     CDS             5747..6085
                     /locus_tag="ctg1_4234"
                     /transl_table=11
                     /translation="LSSNNEYDLFKNRETSLWKRKVPESAALAMTGTVYKLFGNRLLNA
                     RNQLDKNLLEMAMQMVYGKDMVTKSGDILIDIQLNKDGSLQSKHYTLDVGEVINSYNID
                     PLCECFKY"
     CDS             6066..7388
                     /locus_tag="ctg1_4235"
                     /transl_table=11
                     /translation="VNASSINQTYLHDKNPGDVISLYGTLDNIPLVVKECTGKNHQINV
                     KAKLPQERSEKVEDMCERMKGGISMFNHTTKTADNIEHNLQLSFLVGSRPSITNKYSAK
                     DVGPDILALPVNVYHADFKIKINNAVEKASSIVLCAVQKNLHAARKVLSGIIGNVPKNN
                     KPKTIIFDLRFLSAIKQKVFLGSEKPLFVKHTAMMREACKELPQSVEYVPLACEAHSHR
                     SVALAKTVAAPIMATGVGLALMYATSSGPYYAQSLSGSPDIEMIKNRMAELFNQSDISV
                     RNKYSPAFDKWNELVDKLNHERNTVPFACLTTILATAINETLEGDTNVAVVMGCKSAKD
                     RTISIVLGNSMLQTLLEKRLADSGEIENLFDQQGYFSCDSLTPEELMMLKDLFDIRVLH
                     VSNKFNVGLQGNINTDVLQDSFFKNVDFIHEYNSYTVGMGV"
     CDS             7923..8285
                     /locus_tag="ctg1_4236"
                     /transl_table=11
                     /translation="MKQLQRSYYFWKTPRKNKMTCKNPHFFKCFSGVIFAHTLMSNICK
                     VVVMAMNTVFLHLSEEAIKRLNKLRGWRKVSRSAILREAVEQYLERQQFPVRKAKGGRQ
                     KGEVVGVDDQCKEHKE"
     CDS             8503..8745
                     /locus_tag="ctg1_4237"
                     /transl_table=11
                     /translation="MNSLAGIDMGRILLDLSNEVIKQLDDLEVQRNLPRADLLREAVDQ
                     YLINQSQTARTSVPGIWQGCEEDGVEYQRKLREEW"
     CDS             8745..8855
                     /locus_tag="ctg1_4238"
                     /transl_table=11
                     /translation="MGKNDVNQIADNVRVVHAGCGVNALSGLQSHANSIY"
     CDS             complement(9075..10004)
                     /locus_tag="ctg1_4239"
                     /transl_table=11
                     /translation="MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNLYNRRAERLRELA
                     ENNPLGDYLRFAALIAHAQKVVLYDHPLEMDLTARIKEASAQGKPPLDIHVLPRDKHWQ
                     KLLMALIAELKPEMSGPALAVIENLEKASTQELEDMASALFASDFSSVSSDKAPFIWAA
                     LSLYWAQMANLIPGKARAEYGEQRQYCPVCGSMPVSSMVQIGTTQGLRYLHCNLCETEW
                     HVVRVKCSNCEQSGKLHYWSLDDEQAAIKAESCDDCGTYLKILYQEKEPKVEAVADDLA
                     SLVLDARMEQEGYARSSINPFLFPGEGE"
     CDS             complement(10001..10636)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Ni_hydr_CYTB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4240"
                     /sec_met_domain="Ni_hydr_CYTB (E-value: 4.7e-23, bitscore:
                     79.8, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRRDTIVRYTAPERINHWITAFCFILAAVSGLGFLFPSFNWLMQ
                     IMGTPQLARILHPFVGVVMFASFIIMFFRYWHQNLINRDDIFWAKNIRKIVVNEEVGDT
                     GRYNFGQKCVFWAAIIFLVLLLVSGVIIWRPYFAPAFSIPVIRFALMLHSFAAVALIVV
                     IMVHIYAALWVKGTITAMVEGWVTSAWAKKHHPRWYREVRKTTEKKAE"
     CDS             complement(10633..11535)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Form-deh_trans"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Fer4_11"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Fer4_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 23.8; E-value:
                     1.7e-07)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4241"
                     /sec_met_domain="Fer4 (E-value: 2.7e-05, bitscore: 22.0,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_11 (E-value: 2.7e-25, bitscore: 86.5,
                     seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.012, bitscore: 14.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="Form-deh_trans (E-value: 1.5e-20,
                     bitscore: 70.9, seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAYQSQDIIRRSATNGLTPAPQARDFQEEVAKLIDVTTCIGCKAC
                     QVACSEWNDIRDTVGNNIGVYDNPNDLSAKSWTVMRFSEVEQNDKLEWLIRKDGCMHCS
                     DPGCLKACPAEGAIIQYANGIVDFQSEQCIGCGYCIAGCPFDIPRLNPEDNRVYKCTLC
                     VDRVVVGQEPACVKTCPTGAIHFGTKESMKTLASERVAELKTRGYDNAGLYDPAGVGGT
                     HVMYVLHHADKPNLYHGLPENPEISETVKFWKGIWKPLAAVGFAATFAASIFHYVGVGP
                     NRADEEENNLHEEKDEERK"
     CDS             complement(11548..13962)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Molybdopterin"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Molydop_binding"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4242"
                     /sec_met_domain="Molybdopterin (E-value: 4.6e-21, bitscore:
                     73.4, seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Molydop_binding (E-value: 1.7e-16,
                     bitscore: 58.4, seeds: 74, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNHWVDIKNANLVVVMGGNAAEAHPVGFRWAMEAKIHNGAKLIV
                     IDPRFTRTAAVADYYAPIRSGTDIAFLSGVLLYLLNNEKFNHEYTEAYTNASLIVREDY
                     GFEDGLFTGYDAEKRKYDKSSWTYELDENGFAKRDTTLQHPRCVWNLLKQHVSRYTPDV
                     VENICGTPKDAFLKVCEYIAETSAHDKTASFLYALGWTQHSVGAQNIRTMAMIQLLLGN
                     MGMAGGGVNALRGHSNIQGLTDLGLLSQSLPGYMTLPSEKQTDLQTYLTANTPKPLLEG
                     QVNYWGNYPKFFVSMMKAFFGDKATAENSWGFDWLPKWDKGYDVLQYFEMMKEGKVNGY
                     ICQGFNPVASFPNKNKVIGCLSKLKFLVTIDPLNTETSNFWQNHGELNEVDSSKIQTEV
                     FRLPSTCFAEENGSIVNSGRWLQWHWKGADAPGIALTDGEILSGIFLRLRKMYAEQGGA
                     NPDQVLNMTWNYAIPHEPKSEEVAMESNGKALADITDPATGAVIVKKGQQLSSFAQLRD
                     DGTTSCGCWIFAGSWTPEGNQMARRDNADPSGLGNTLGWAWAWPLNRRILYNRASADPQ
                     GNPWDPKRQLLKWDGTKWTGWDIPDYSAAPPGSGVGPFIMQQEGMGRLFALDKMAEGPF
                     PEHYEPFETPLGTNPLHPNVISNPAARIFKDDAEALGKADKFPYVGTTYRLTEHFHYWT
                     KHALLNAILQPEQFVEIGESLANKLGIAQGDTVKVSSNRGYIKAKAVVTKRIRTLKANG
                     KDIDTIGIPIHWGYEGVAKKGFIANTLTPFVGDANTQTPEFKSFLVNVEKV"
     CDS             complement(14011..14598)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Molybdop_Fe4S4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Formate_dehydrogenase: Molybdopterin"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4243"
                     /sec_met_domain="Molybdop_Fe4S4 (E-value: 1.1e-19,
                     bitscore: 68.3, seeds: 55, tool: rule-based-clusters)"
                     /sec_met_domain="Molybdopterin (E-value: 7.5e-07, bitscore:
                     26.6, seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQVSRRQFFKICAGGMAGTTAAALGFAPSVALAETRQYKLLRTRE
                     TRNTCTYCSVGCGLLMYSLGDGAKNAKASIFHIEGDPDHPVNRGALCPKGAGLVDFIHS
                     ESRLKFPEYRAPGSDKWQQISWEEAFDRIAKLMKEDRDANYIAQNAEGVTVNRWLSTGM
                     LCASASSNETGYLTQKFSRALGMLAVDNQARV"
     CDS             14792..15625
                     /locus_tag="ctg1_4244"
                     /transl_table=11
                     /translation="VKKTQRKEIENVTNITGVRQIELWRRDDLQHPRLDEVAEEVPVAL
                     VYNGISHVVMMASPKDLEYFALGFSLSEGIIESPRDIFGMDVVPSCNGLEVQIELSSRR
                     FMGLKERRRALAGRTGCGVCGVEQLNDIGKPVQPLPFTQTFDLNKLDDALRHLNDFQPV
                     GRLTGCTHAAAWMLPSGELVGGHEDVGRHVALDKLLGRRSQEGESWQQGAVLVSSRASY
                     EMVQKSAMCGVEILFAVSAATTLAVEVAERCNLTLVGFCKPGRATVYTHPQRLSN"
     CDS             complement(15697..16200)
                     /locus_tag="ctg1_4245"
                     /transl_table=11
                     /translation="MSRQCTHYGRWPQHGFTSLKKLRPQSVTSHIQPGSDVIVCAEMDE
                     HWGYVGAKSRQRWLFYAYDRIRRTVVAHVFGERTLATLERLLSLLSAFEVVVWMTDGWP
                     LYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSFSKSVELHDKVIGHYLNI
                     KHYQ"
     CDS             complement(16428..17078)
                     /locus_tag="ctg1_4246"
                     /transl_table=11
                     /translation="MLNERQLKIVDLLEQQPRTPGELAQQTGVSGRTILRDIDYLNFTL
                     NGKARIFASGSAGYQLEIFERRSFFQLLQKHDNDDRLLALLLLNTFTPRAQLASALNLP
                     ETWVAERLPQLKQRYERTCCLASRPGLGHFIDETEEKLVILLANLLRKDPFLIPLAGIT
                     RDNLQHLSTACDNQHRWPLIQGDYLSSLILAIYALRNQLTDEWPQYPVMLPTY"
     CDS             complement(17078..18148)
                     /locus_tag="ctg1_4247"
                     /transl_table=11
                     /translation="MNIELLQQLCEASAVSGDEQEVRDILINTLEPCVNEITFDGLGSF
                     VARKGNKGPKVAVVGHMDEVGFMVTHIDESGFLRFTTIGGWWNQSMLNHRVTIRTHKGV
                     KIPGVIGFVAPHALTEKQRQQPLSFDEMFIDIGANSRDEVEKRGVAMGDFISPEANFAC
                     WGEDKVVGKALDNRIGCAMMAELLQTVNNPEITLYGVGSVEEEVGLRGAQTSAEHIKPD
                     VVIVLDTAVAGDVPGIDNIKYPLKLGQGPGLMLFDKRYFPNQKLVAALKNCAAHNDLPL
                     QFSTMKTGATDGGRYNVMGGGRPVVALCLPTRYLHANSGMISKADYDALLTLIRGFLTT
                     LTAEKVNAFSQFRQVD"
     CDS             complement(18138..19589)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTS_EIIC"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4248"
                     /sec_met_domain="PTS_EIIC (E-value: 1.7e-28, bitscore:
                     97.7, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESSLRIVAITNCPAGIAHTYMVAEALEQKARSLGHTIKVETQGS
                     SGVENRLSSEEIAAADYVILATGRGLSGDDRARFAGKKVYEIAISLALKNIDQIFSELP
                     TNSQLFAADSGVKLGKQEVQSGSVMSHLMAGVSAALPFVIGGGILVALANMLVQFGLPY
                     TDMSKGAPSFTWVVESIGYLGFTFMIPIMGAYIASSIADKPAFAPAFLVCYLANDKALL
                     GTQSGAGFLGAVVLGLAIGYFVFWFRKVRLGKALQPLLGSMLIPFVTLLVFGVLTYYVI
                     GPVMSDLMGGLLHFLNTIPPSMKFAAAFLVGAMLAFDMGGPINKTAWFFCFSLLEKHIY
                     DWYAIVGVVALMPPVAAGLATFIAPKLFTRQEKEAASSAIVVGATVATEPAIPYALAAP
                     LPMITANTLAGGITGVLVIAFGIKRLAPGLGIFDPLIGLMSPVGSFYLVLAIGLALNIS
                     FIIVLKGLWLRRKAKAAQQELVHEH"
     CDS             complement(19600..20046)
                     /locus_tag="ctg1_4249"
                     /transl_table=11
                     /translation="MAALTASCIDLNIQGNGAYSVLKQLATIALQNGFITDSHQFLQTL
                     LLREKMHSTGFGSGVAVPHGKSACVKQPFVLFARKAQAIDWKASDGEDVNCWICLGVPQ
                     SGEEDQVKIIGTLCRKIIHQEFIHQLQQGDTDQVLALLNQTLSS"
     CDS             complement(20347..20661)
                     /locus_tag="ctg1_4250"
                     /transl_table=11
                     /translation="MIRKAFVMQVNPDAHEEYQRRHNPIWPELEAVLKSHGVHNYAIYL
                     DKARNLLFAMVEIESEERWNAVASTDVCQRWWKYMTDVMPANPDNSPVSSELQEVFYLP
                     "
     CDS             complement(20671..21312)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldolase_II"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4251"
                     /sec_met_domain="Aldolase_II (E-value: 1.4e-30, bitscore:
                     104.8, seeds: 389, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLLANTPFIVTGSGKFFRNVQLDPAANLGVVKVDSDGAGYHILW
                     GLTNEAVPTSELPAHFLSHCERIKATNGKDRVIMHCHATNLIALTYVLENDTAVFTRQL
                     WEGSTECLVVFPDGVGILPWMVPGTDEIGQATAQEMQKHSLVLWPFHGVFGSGPTLDEA
                     FGLIDTAEKSAQVLVKVYSMGGMKQTISREELIALGKRFGVTPLASALAL"
     CDS             complement(21737..22996)
                     /locus_tag="ctg1_4252"
                     /transl_table=11
                     /translation="MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDDV
                     SGFENPEGSLTGGIQATGNYPGKARNASELRADLEQAMRLIPGPKRLNLHAIYLESDTP
                     VSRDQIKPEHFKNWVEWAKANQLGLDFNPSCFSHPLSADGFTLSHPDDSIRQFWIDHCK
                     ASRRVSAYFGEQLGTPSVMNIWIPDGMKDITVDRLAPRQRLLAALDEVISEKLNPAHHI
                     DAVESKLFGIGAESYTVGSNEFYMGYATSRQTALCLDAGHFHPTEVISDKISAAMLYVP
                     QLLLHVSRPVRWDSDHVVLLDDETQAIASEIVRHDLFDRVHIGLDFFDASINRIAAWVI
                     GTRNMKKALLRALLEPTAELRKLEAAGDYTARLALLEEQKSLPRQAVWEMYCQHHDTPA
                     GSEWLESVRAYEKAILSQRG"
     CDS             complement(22993..24462)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4253"
                     /sec_met_domain="FGGY_C (E-value: 2e-25, bitscore: 87.8,
                     seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="FGGY_N (E-value: 3e-29, bitscore: 100.4,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTFRNCVAVDLGASSGRVMLARYERECRSLTLREIHRFNNGLHSQ
                     NGYVTWDVDSLESAIRLGLNKVCEEGIRIDSIGIDTWGVDFVLLDQQGQRVGLPVAYRD
                     SRTNGLMPQAQQQLGKRDIYQRSGIQFLPFNTLYQLRALTEQQPELIPHIAHALLMPDY
                     FSYRLTGKMNWEYTNATTTQLVNINSDDWDESLLAWSGANKAWFGRPTHPGNVIGHWIC
                     PQGNEIPVVAVASHDTASAVIASPLNGSRAAYLSSGTWSLMGFESQTPFTNDTALAANI
                     TNEGGAEGRYRVLKNIMGLWLLQRVLQERQINDLPALIAATQALPACRFIINPNDDRFI
                     NPDEMCSEIQAACRETAQPIPGSDAELARCIFDSLALLYADVLHELAQLRGEDFSQLHI
                     VGGGCQNTLLNQLCADACGIRVIAGPVEASTLGNIGIELMTLDELNNVDDFRQVVSTTA
                     NLTTFTPNPDSEIAHYVAQIHSTRQTKELCA"
ORIGIN
        1 caaacggtat aaccaggcga aatcttcgca atccgccatc atggtggata ccaaaggcga
       61 gcggataatc attaactacc ccagcccgga tctgctgcct gacgcagagt ggttggagga
      121 aattgatttc tctcagtggg atgttgtgct ggcagatgta cgctggcacg acggcgctaa
      181 aaaagccttc accctggccc gtcaggcggg tgtgatgacc gttctggacg gggacattac
      241 gccgcaggat atcagtgagc tggtggcatt aagcgatcac gcggcctttt cagaaccggg
      301 tctggcgcgc ttaacgggcg tgaaagagat ggccagtgcg ctaaaacagg cacaaacgct
      361 cacaaatggt catgtctatg tgacccaggg tagcgcaggc tgcgactggc tggaaaatgg
      421 tgggcgtcag catcaaccgg ccttcaaagt tgatgtggta gataccacag gtgcgggtga
      481 tgtttttcac ggcgctttgg cggtggcgct ggcaacaagt ggggatttag cggagtcagt
      541 ccgcttcgcc agcggtgtag cggcgttaaa atgcacacgt cccggtggac gagccgggat
      601 ccctgactgt gatcaaaccc gatctttttt gtcacttttt gtataaaatg ccagggtgat
      661 ggtttttcga ggaattttca tgagccttac cgaactaacc ggtaacccgc ggcacgacca
      721 actcctcatg ctgatcgccg agcgtgggta tatgaatatt gatgagctgg caaatctgct
      781 ggatgtctcc acgcagacgg tccgccggga tattcgtaaa ttaagcgagc aaggcctgat
      841 tacgcgccat cacggtggcg cgggtcgggc ttccagcgtc gttaatacgg cgttcgagca
      901 gcgtgaggtt tcgcaaaccg agaaaaaaaa agcgattgcc gaagcggtgg cagactatat
      961 tcctgatggt tcaacaatat ttatcaccat tggtacgact gttgagcatg ttgcccgggc
     1021 gttacttaac cataatcatt tgcggataat caccaacagc ctgcgtgtgg cgcatattct
     1081 ttaccacaac ccgcgctttg aagtgatggt gcccggcggt acgttgcgct ctcataatag
     1141 cgggatcatt ggcccttcag cggcgtcctt tgtggctgat tttcgtgctg attatctggt
     1201 aacaagcgtt ggggcgattg agagcgatgg cgcgttgatg gagtttgatg taaacgaagc
     1261 taacgtggtg aaaacgatga tggcgcacgc gagaaatatt ctgctggtcg ccgatcacac
     1321 taagtatcat gcttcggcgg cggttgaaat tggtaacgtg gcacaggtca ctgcgctctt
     1381 taccgacgag ctgccgcccg ctgcgctaaa atcacgctta caagacagcc aaattgaaat
     1441 cattcttccc caggaagacg cgtagatttt tgtgaccgtt aacctggctt cataccttgc
     1501 cacatagcca aacccatcct ttcccgctac agttaatttc ttgtggcgcg aaaggaggca
     1561 aaaatgctct atatctttga tttaggtaat gtgattgtcg atatcgactt taaccgtgtg
     1621 ctgggagcct ggagcgattt aacgcgtatt ccgctggcat cgcttaagaa gagttttcat
     1681 atgggggagg cgtttcatca gcatgagcgt ggggaaatta gcgacgaagc gttcgcagag
     1741 gcgctgtgtc atgagatggc tctaccgcta agctacgagc agttctctca cggctggcag
     1801 gcggtgtttg ttgcgctgcg cccggaagtg atcgccatca tgcataaact gcgtgagcag
     1861 gggcatcgcg tggtggtgct ttccaatacc aaccgcctgc ataccacctt ctggccggaa
     1921 gaatacccgg aaattcgtga tgctgctgac catatctatc tgtcgcaaga tctggggatg
     1981 cgcaaacctg aagcacgaat ttaccagcat gttttgcagg cggaaggttt ttcacccagc
     2041 gatacggtct ttttcgacga taacgccgat aatatagaag gagctaatca gctaggcatt
     2101 accagtattc tggtgaaaga taaaaccacc atcccggact atttcgcgaa ggtgttatgc
     2161 taaaaaccat tcaggacaaa gccaggcacc gtacccgtcc actatgggcc tggctaaaac
     2221 tactctggca acgtattgat gaggacaaca tgacaaccct ggcaggtaac cttgcctatg
     2281 tgtcgttgct ctcattagtg ccgctggttg ccgttgtttt tgcgcttttc gccgcttttc
     2341 ccatgttttc cgacgtcagc attcagttac gtcactttat ttttgccaac tttctgcctg
     2401 ctactggcga tgttattcag cggtatatcg aacaatttgt tgctaattcc aacaagatga
     2461 ccgccgttgg ggcgtgcggg ctgatcgtca ccgcgttatt gttgatgtac tccatcgata
     2521 gcgcgttgaa taccatctgg cgcagtaaac gagcgcgacc aaaaatttac tcgttcgccg
     2581 tgtactggat gattttaacg ctggggccgc tgctggcagg ggccagtctg gcgatcagtt
     2641 cctatttgct ccccctgcgc tgggcgagcg atctcaatac tgtcatcgac aacgtgctgc
     2701 gtatttttcc gttgctgttg tcgtggatct ccttctggtt gctgtacagc attgttccta
     2761 ccatccgcgt acctaaccgc gacgcgattg tcggcgcgtt tgtcgccgca ctcctgttcg
     2821 aagcaggaaa gaaaggtttc gcgctttata tcaccatgtt cccgtcatat cagctcattt
     2881 acggtgtgct ggcggtgatc cccattctct ttgtttgggt ctactggaca tggtgtatcg
     2941 tcttgcttgg cgcggaaatt actgtcactc tcggggaata ccgcaaacta aaacaagcag
     3001 ctgaacaaga agaagacgac gaaccatgat tgcattaatt caacgcgtaa cccgtgccag
     3061 cgtcaccgtg gagggagaag tgacgggcga aattggcgcg ggacttttgg tgttattggg
     3121 tgtcgaaaag gatgacgacg aacagaaagc aaaccgtctg tgcgagcgtg tgctcggcta
     3181 ccgcatcttt agcgatgccg aaggcaagat gaatctcaac gtgcaacagg cgggcggcag
     3241 tgtactggtg gtttcccagt ttaccctcgc cgcagatacc gaacggggga tgcgcccaag
     3301 tttctccaaa ggcgcatcac cggatcgcgc agaggcgtta tatgactatt tcgtcgaacg
     3361 ctgccgccag caagagatga acacgcaaac aggacgcttc gctgccgata tgcaggtatc
     3421 gctggtcaat gatggccccg tgacattctg gttgcaggta tgagccagct tccagggttg
     3481 tcacgggaaa caagagagag tatcgctatg tatcaccttc aggttccaca aacagaagaa
     3541 gagttagagc gttactatca ctttcgctgg gaaatgttgc gtaagcccct gcatcaacca
     3601 aaaggttcgg aacgcgacgc gtgggatgcg atggcgcatc accagatggt cgtcgacgag
     3661 cagggtaatc tggtggcggt aggccgattg tatattaatg ccgacaatga agcgtccatt
     3721 cgctttatgg tcgttcaccc ggacgtgcag gacaaagggt taggaacgct gatggcgatg
     3781 accctggagt cggtggcgcg tcaggaaggc gttaagcgcg tgacctgtag cgcccgtgaa
     3841 gacgcggtgg agtttttcgc caagctgggg tttgttaatc agggagaaat caccacgcca
     3901 accaccacgc cgattcgcca ttttttgatg attaagcccg tcgccactct ggatgatatt
     3961 ttgcatcgcg gcgactggtg cgcgcagctg caacaggcgt ggtacgaaca tatcccgctt
     4021 agtgaaaaaa tgggcgtgcg tattcaacaa tataccgggc aaaaatttat caccaccatg
     4081 ccggaaaccg gcaatcagaa tccgcaccat acgctgtttg ccgggagttt attctcgctg
     4141 gcgacgctca ccggttgggg gcttatctgg ctgatgctgc gtgaacgcca cctcggcgga
     4201 acgattattc tggcggatgc gcatatccgc tacagcaaac cgattagcgg taaaccccat
     4261 gcggtagccg accttggtgc cttaagcggc gatctcgacc gtctggcgcg cggacgaaaa
     4321 gcacgggtgc agatgcaggt cgaaatcttt ggcgacgaga cgccgggtgc agtgtttgaa
     4381 ggcacgtata tcgttctgcc cgcgaagcca tttggcccgt atgaagaggg cgggaacgaa
     4441 gaagagtagc ttatggagag gggcggtgct gcctctctca ttcattccgg tcatttacat
     4501 cagtccctga ctattccggt tatattgaat aagaacttta taaattttta ttcttcgttg
     4561 gcaccatacg tgtcttgcta catcactgtt caggagcatt taaatattat ttgtagagct
     4621 gagtggcaat tattgcagat aatgcttaac tcatcatatt agttcaggtt tgagcgattt
     4681 ttgatagtca aaaccccctc tggtgccata cttttttcat aaatattttt aaaatctata
     4741 gctcacaaat attatgcaaa gataatgggc tggcatacat tgtcagtatc attcatttac
     4801 tgctctgtat gttatgaatc attatgttgt atgtttgctc ttaaaccgtg ggaaggaggc
     4861 tataatggtt gccaatatta atctcattaa acaagaaagt tattctgttg ttaatttaga
     4921 aaaacaacta atgagtaata aatcaccgaa gcaaacgcta ttaaatcaat tttcaggtaa
     4981 tgactccaac ttactgatag tgttttatgt tcagataatg cccgatgacc ttgtcatgca
     5041 gctccaccga ttttgagaac gacagtgact tccgtaccag ccttgccaga tgttgtctca
     5101 gattcagatt atgtcgctca atgcgctgag tgtaacgctt gctgataacg tgcagctttc
     5161 ccttcaggcg tgattcatac agcggccagc catccgtcat ccataccacg acctcaaagg
     5221 ccgacagcag gctcagaaga cgctccagtg tggccagagt gcgttcaccg aagacgtgcg
     5281 ccacaaccgt cctccgtatc ctgtcatacg cgtaaaacag ccagcgctga cgtgatttag
     5341 caccgacgta gccccaatgt tcgtccattt cagcgcagac aatcacatca ctgcccggtt
     5401 gtatgcgcga ggttaccgac tgcggcctga gttttttaag tgacgtaaaa ccgtgttgag
     5461 gccaacgccc ataatgcgtg cactggcgcg acatccgacg ccattcatgg ccatatcaat
     5521 gattttctgg tgcgtaccgg gctgagaggc ggtgtaagtg aactgtagtt gccatgtttt
     5581 acggcaatga gagcagagat agcgcagatg tccggcagtg cttttgccgt tacgcaccac
     5641 gccttcagta gcggagcagg aaggacatct gatggaaatg gaagccacgc aagcacctta
     5701 aaatcaccat catacactaa atcagtaagt tggcagcatt accggtttgt cgagtaataa
     5761 tgaatatgac ctgtttaaaa atagagaaac ctcactgtgg aaacgcaaag taccagaaag
     5821 cgcagcgctg gcaatgacgg gaacagtata taaattattt ggtaatcgct tactcaacgc
     5881 ccgcaatcag ttagataaaa atctcctcga aatggctatg caaatggttt atggcaaaga
     5941 tatggtgaca aagtccgggg atatattgat tgatatacaa ttaaataagg atggcagtct
     6001 ccagagtaag cactacacac ttgatgtagg tgaagttata aacagttata atattgaccc
     6061 tctttgtgaa tgcttcaagt attaatcaaa cttacttaca tgataaaaat cctggtgacg
     6121 ttattagcct gtatggcact ttagataaca ttccccttgt agttaaggaa tgcacgggta
     6181 aaaatcatca aattaatgtt aaagccaaat tgccacaaga acgaagtgaa aaagttgagg
     6241 atatgtgtga aagaatgaaa ggtggcatct ctatgtttaa ccacaccaca aaaacagctg
     6301 ataatataga gcataatttg cagctaagtt ttctcgtggg ttcacgtccg tcgatcacca
     6361 ataaatactc agcaaaagat gtaggtccag atatacttgc attgcccgtc aacgtatatc
     6421 atgcggattt taaaattaaa atcaataatg cagtggagaa ggcttcatca attgtgttat
     6481 gtgctgtgca aaaaaatctc catgcagcaa ggaaggttct tagcgggata ataggaaatg
     6541 tgccaaaaaa taataaacca aaaacaatta tttttgattt gcgttttctt agtgcaatta
     6601 agcagaaagt ttttttgggc agtgaaaaac cgttgtttgt aaagcatacc gcaatgatga
     6661 gggaggcatg taaggaatta ccgcagtcag tggaatatgt tcctttagcc tgtgaagcgc
     6721 atagccatcg cagcgtcgcc cttgccaaaa ccgtggctgc gcccatcatg gcgacaggtg
     6781 tgggcttggc attaatgtat gcaacatcat caggaccgta ttatgcgcaa agtctttctg
     6841 gttcgccgga tatcgagatg ataaaaaatc gcatggctga attgtttaac cagtcggata
     6901 tttctgtgcg caacaaatat agcccggctt ttgataaatg gaatgaactg gtagataaat
     6961 taaatcacga aagaaataca gttccgtttg cgtgtttgac caccatttta gcgacggcga
     7021 taaatgaaac tcttgagggg gatacgaatg ttgccgttgt gatggggtgt aaatctgcga
     7081 aagatcgcac gatatccatt gtccttggca actcgatgtt gcaaacactc cttgaaaaac
     7141 gcctcgccga tagtggagaa atagaaaatc tttttgatca acagggatat tttagttgcg
     7201 attcattaac acccgaagaa ttaatgatgt taaaagacct ttttgatatt cgagttcttc
     7261 atgtctctaa caaattcaat gttggattgc aaggtaatat caacactgat gttttacaag
     7321 attcgttttt taaaaatgtc gatttcattc atgaatataa ctcgtatacc gtagggatgg
     7381 gagtctgacg agtaaaactc attaggatta tcagaattcg gacaatgcat tgcaaaaatg
     7441 acatacaaag agagatgtgt gcaggtactt agccgcgagg ggcatggcga agccatacag
     7501 aaagtaccag tattcagaac tccagtgaaa gcggcatagt ggccgcctgc tcaggagttt
     7561 tgctatgacc cgtaatcgtg ctgaacgtcg ccaccctatg atgcgattaa aaaaactcat
     7621 cgtcgcgctg atgattgacg tcaatgctat cggatgatgc cgggggtgtt ccggaaggaa
     7681 ttccttgttt cccgaactgt taccaacaaa attataacga tgagcaagta aagaccggtt
     7741 ggtggcagta ctgaccggtc tgtgatgaaa gattaatttc accttaaatc ctggtgctgt
     7801 taggatgctg acgtttttcg gctacaccat tcagattatg taaataaata tccctgaata
     7861 taatatattc atagcaccca taactcatcc tgggcgataa ctaaaccatt tttgagtaat
     7921 aaatgaaaca actgcaacgc tcttattatt tctggaaaac gcctcgcaaa aacaaaatga
     7981 catgcaaaaa tccgcatttt tttaaatgct tttccggcgt aattttcgca catacattaa
     8041 tgagtaatat atgtaaggtg gtggtaatgg cgatgaatac ggtttttctt catttatcag
     8101 aagaggcaat taaacggctg aacaagcttc ggggctggcg taaggtttca cgatctgcaa
     8161 ttttacgcga agcggttgag caatatctgg agcggcagca atttccggtg cgtaaagcaa
     8221 agggaggcag gcaaaagggg gaggtagttg gtgttgatga tcagtgtaag gagcataagg
     8281 aatgaaaaaa atttttcatt cttgaatata aaaaacagat gcccttattc tggtattaat
     8341 acaaggctgt tttacttgaa cttataataa ctgcaactgt tacatcgtat ctggaaaacg
     8401 cctcgcaaaa ataaaaaatg atgcgtaaat gagctttctt taaagattcg gcaagggtac
     8461 ttttctctcc atagattcaa aaatgatatt ggcgagatat ttatgaactc tctggcaggt
     8521 atagatatgg gcagaatttt actcgattta tcgaatgagg tgattaagca acttgatgat
     8581 ctcgaggtgc agcgtaatct tcctcgtgcg gacctattaa gggaagcggt agatcaatac
     8641 ctgataaatc aatcgcaaac agcaagaacc agtgttcctg gcatctggca agggtgtgag
     8701 gaagatggtg tcgaatatca gcgtaagctg cgcgaggaat ggtaatggga aaaaatgatg
     8761 tcaatcagat tgctgacaac gtgcgcgttg ttcatgccgg atgcggcgtg aacgccttat
     8821 ccggcctaca aagtcatgca aattcaatat attgaagttt attggtaggc ctgataagcg
     8881 cagcgcatca ggcaatcata cgcttgtcat cagtgacata cccataacct tatcgatgtg
     8941 ttggagggaa gaacgaggca aacagacaat tgcggcatga tcttgaatgg gtaacgcgga
     9001 atacgagaga tggtgtcgtc acaccctatg agctgtaatc cgggcgacct gcgccacccg
     9061 gaaaacgtca gagattactc tccttcaccc ggaaacagga acgggttaat ggaactacgg
     9121 gcgtagcctt cttgctccat tcgcgcgtcc agtaccagag aggcgaggtc atctgccacg
     9181 gcttcaactt tcggttcttt ttcctgataa agaatcttca ggtaagtgcc gcagtcatcg
     9241 cagctttcgg ctttaatcgc ggcctgttcg tcatccagcg accagtaatg cagtttgccg
     9301 ctctgctcgc agttgctgca ttttacgcgc actacgtgcc attcggtttc acacaggttg
     9361 cagtgcaggt aacgcagacc ctgagtggtg ccaatttgca ccatgctgga caccggcata
     9421 gagccacata ccgggcaata ttgacgttgt tcgccgtatt cagcgcgggc tttgccgggg
     9481 atcagattgg ccatctgcgc ccagtagagc gacagcgcag cccagataaa cggcgcttta
     9541 tcgctgctga cggacgagaa atcagaggca aacagcgcgc tggccatatc ttccagctcc
     9601 tgagtcgatg ccttctccag attctcaatc actgccagcg ccgggccgct catttcaggt
     9661 ttcagctcag caattagcgc catcagcagc ttttgccagt gcttatcacg cggcagaacg
     9721 tgaatatcca gcgggggctt gccctgtgcg ctggcttctt taatgcgcgc ggtcagatcc
     9781 atctccagcg gatggtcgta cagcaccact ttctgggcgt gggcgataag cgcagcaaag
     9841 cgcaggtaat cacccagcgg attattttct gccagctcgc gcagacgctc ggcgcggcgg
     9901 ttgtataaat tcttgagccg agggaacaat aacggcggaa tcatatccgc cgtacgtttc
     9961 tcgctcgaac ccagctcatc ttgcgggatt atgcgaatac tcattcagct ttcttttccg
    10021 ttgtcttgcg gacctcacgg taccagcgcg ggtgatgttt cttcgcccag gcgctggtaa
    10081 cccatccttc caccatggcg gtaatcgtgc ctttcaccca aagggcggcg tagatatgca
    10141 ccatgataac cacaattaac gccactgcgg caaatgaatg cagcattaac gcgaatcgga
    10201 tcaccgggat tgagaaagca ggcgcaaaat aaggacgcca gataatcacg ccgctcacca
    10261 gcagcagaac caggaaaata atcgccgccc agaaaacgca tttctgaccg aagttataac
    10321 gcccggtgtc acctacttcc tcgttgacga cgatcttacg aatattcttc gcccaaaaga
    10381 tatcatcccg attgattagg ttttgatgcc agtaacggaa aaacatgatg atgaacgagg
    10441 caaacataac cacgccgaca aacgggtgca gaattcgcgc cagctgcggt gtgcccatga
    10501 tttgcatcaa ccagttgaag gacgggaaca aaaagcccag cccgctcacc gccgccagga
    10561 tgaagcagaa ggcggtgatc cagtggttga tacgttccgg cgcggtgtag cgcacgatgg
    10621 tgtcacgtcg tttcatttgc gctcctcgtc tttctcttcg tgcagattat tctcttcctc
    10681 atccgcacgg ttcggaccga cacccacgta gtggaagata ctggccgcaa aggtagccgc
    10741 aaagccaaca gccgcgagcg gtttccagat gcctttccag aatttcacgg tttcgctgat
    10801 ttccgggttc tccggcaagc catgatacag atttggcttg tcagcatggt gcagcacgta
    10861 catgacgtgt gtaccaccga cgcctgccgg atcgtacaga cccgcattgt cgtaaccgcg
    10921 ggttttcagc tcagcaacgc gctcgctcgc cagcgttttc atcgactctt tcgtgccgaa
    10981 gtgaatcgcg cccgttgggc aggtcttcac gcaggctggt tcttgcccaa ccaccacgcg
    11041 gtcaacgcac agcgtacatt tgtagacgcg gttgtcttcc gggttgaggc gcggaatgtc
    11101 gaacggacag cccgcaatgc aataaccgca gccaatgcac tgctcggact ggaagtcgac
    11161 gataccgttg gcatactgaa taattgcacc ttccgccggg cacgctttca ggcagcctgg
    11221 atcggaacag tgcatacagc cgtctttgcg gatcagccat tccagtttgt cgttctgctc
    11281 cacttccgag aagcgcatta ccgtccacga tttggcgctt aaatcattgg ggttgtcgta
    11341 caccccaatg ttattgccga cggtatcgcg aatgtcgttc cactctgaac acgccacctg
    11401 acaggcttta cagccgatac aggtggtaac gtcgatgagt ttcgccactt cttcctggaa
    11461 gtcccgcgcc tgaggcgcgg gggtcagacc gttagtcgcg gaacgacgaa tgatatcttg
    11521 agattgataa gccatatgtc gtctccgtta caccttttcc acattcacaa ggaaggactt
    11581 aaactccggc gtctgcgtgt tcgcatcacc aacgaatggc gttaaagtat tggcaataaa
    11641 gcctttttta gctacgcctt catagcccca gtgaatcgga ataccgatgg tatcgatatc
    11701 tttgccgttc gctttcagcg tgcgaatacg tttggtcacc accgctttgg ctttgatata
    11761 gccacggttg gaggagactt tcacggtatc gccctgggca atgccaagtt tattcgccag
    11821 cgactccccg atttccacaa actgctctgg ctgcaaaatc gcgttcaaca gcgcgtgttt
    11881 ggtccagtag tggaagtgct cggtcagacg ataggtggtt ccgacatacg ggaacttatc
    11941 ggctttaccc aatgcttcgg cgtcgtcttt aaagatacgt gcagctgggt tcgagataac
    12001 gtttggatgc agcgggttag ttcccagcgg cgtttcaaac ggctcgtagt gttccgggaa
    12061 cggaccttcc gccatcttat cgagggcaaa cagacgcccc atgccttcct gctgcatgat
    12121 aaacggcccg acgccgctac ccggaggcgc tgcgctgtag tccggaatat cccagccggt
    12181 ccacttagtg ccgtcccatt tcagcaactg acgcttcgga tcccacgggt taccctgcgg
    12241 atctgcggag gcgcggttat acagaatgcg gcggttaagc ggccatgccc atgcccagcc
    12301 cagcgtgtta ccgaggccag acggatcggc gttatcacga cgcgccatct ggttgccttc
    12361 cggcgtccag ctaccggcga aaatccagca gccacaggag gttgtaccgt catcgcgcaa
    12421 ttgggcgaac gagctaagtt gttggccttt cttgacgata accgcaccgg ttgccggatc
    12481 ggtaatatcg gccagcgcct taccgttgct ctccatcgct acttcttccg acttcggctc
    12541 atgcggaatg gcgtagttcc aggtcatgtt cagcacctga tccgggttcg cgccaccctg
    12601 ttcggcatac atcttgcgca agcgcaggaa gataccggag aggatctcac cgtcagtcag
    12661 cgcaatcccc ggggcgtccg cacctttcca gtgccactgc aaccagcgac ctgagttaac
    12721 gattgaaccg ttctcttctg cgaagcaggt cgatggcaga cggaacactt cggtctggat
    12781 cttcgacgag tcaacttcgt tcagctcacc gtggttctgc cagaagttag aggtttcagt
    12841 gttcagtggg tcgatggtga cgaggaactt cagtttcgac agacaaccga tcactttgtt
    12901 tttgttcggg aatgaggcaa cagggttaaa gccctggcag atatagccat tgaccttgcc
    12961 ctctttcatc atctcgaagt attgcaggac gtcgtagcct ttatcccact tcggcaacca
    13021 gtcaaagccc cagctatttt ccgccgtcgc tttatcacca aagaaggcct tcatcataga
    13081 gacgaagaat ttcgggtagt tgccccagta gtttacctgg ccttccagca gcggttttgg
    13141 cgtgttggcg gtaaggtagg tttgcagatc ggtctgcttc tcgcttggca gcgtcatgta
    13201 acctggcaga ctctgcgaca gtagccccag gtccgtcagc ccctgaatat tggagtgacc
    13261 gcgcagggcg ttaacgccgc cgccggccat ccccatattg ccgagcagca gctggatcat
    13321 cgccatcgta cgaatgtttt gcgcaccaac ggagtgttgc gtccagccga gggcatacag
    13381 gaacgaggca gttttatcgt gagcactggt ttctgcgatg tattcgcaga ctttcaggaa
    13441 cgcgtctttt ggcgtaccac agatgttttc aaccacatct ggcgtgtagc gggaaacgtg
    13501 ctgtttcagc aagttccaca cgcagcgcgg atgttgcagc gtggtatcgc gtttggcgaa
    13561 gccgttttcg tccagttcat aagtccagga ggatttatcg tacttgcgtt tttccgcgtc
    13621 gtagccggtg aacaggccat cttcaaagcc gtaatcctca cgcacgatca ggctggcgtt
    13681 ggtataggct tcggtgtatt cgtggttgaa tttttcattg ttcagcaggt acagcaatac
    13741 gcctgacagg aaagcaatgt cagtaccgga acgaataggg gcatagtagt cagctaccgc
    13801 cgccgtacgc gtaaagcgag gatcgatcac aatcagcttc gcgccgttgt gaattttggc
    13861 ttccatcgcc cagcggaacc cgaccgggtg agcttcagcg gcgttaccgc ccatcaccac
    13921 gacgaggttg gcgttcttga tgtcgaccca gtggttggtc atcgcaccgc gaccaaatgt
    13981 tggagcaaga cttgctaccg ttggtccgtg tcagacacgc gcctggttgt cgaccgcgag
    14041 catacccagc gcgcgggaga atttttgcgt taaatagccg gtttcgttac tcgacgcgga
    14101 agcacacagc atcccggtgg agagccagcg gttaacagtc acgccttcgg cgttttgcgc
    14161 aatgtagtta gcatcgcggt cttctttcat cagtttggcg atgcgatcaa acgcctcttc
    14221 ccaactgatt tgctgccatt tatcagaacc tggcgcacgg tattccggaa acttcagacg
    14281 gctttcggag tggatgaaat ccaccaggcc agcgcctttc ggacaaagtg caccgcggtt
    14341 gaccgggtga tccggatcgc cttcgatatg gaagatagat gctttggcgt tttttgctcc
    14401 gtcaccgagg ctgtacatca acagcccaca gcctacggaa caataggtgc aggtattacg
    14461 ggtttcgcgg gtgcgcagca gtttatactg ccgggtttcc gcgagtgcta cgctgggtgc
    14521 aaaacccagt gccgctgccg tggtgcctgc cataccgcca gcgcagatct taaagaactg
    14581 ccttctgctg acctgcatgg attgctcctt gtttcgacat tgtcacgtcc catttacatt
    14641 cgcttgctgc gtgtgcaggg agtgggagtt atttttcttt gcggaagggg ccgcaaaggt
    14701 ccagaattgg ctcaatttcc ctccatctag gaagggtttg taacagaata ccataatgtt
    14761 ggtgtgtatg ttcttatctg gttaagagaa agtgaaaaaa acacagcgaa aagaaatcga
    14821 aaatgtgaca aatatcacag gtgttcgtca aattgagtta tggcggcgtg atgatttaca
    14881 acacccacgg ttagatgagg tcgcggaaga agttcccgtt gcgctggtct acaacggcat
    14941 ttcgcatgtg gtgatgatgg cgtcgcccaa agaccttgag tactttgcgc tcggtttttc
    15001 gctttccgag gggataatag aaagtccgcg cgatatcttc ggcatggatg tcgttccttc
    15061 ctgtaatggt cttgaagtac aaattgagct ttccagccgc cgctttatgg ggttgaagga
    15121 gcgccgccgg gcgctggcgg gacgtacggg ctgtggcgta tgcggcgtgg agcaacttaa
    15181 tgacatcgga aaaccggtgc agccgctacc gttcacccag acgtttgatc tcaacaaact
    15241 ggatgatgca ttacgtcatc tcaacgattt tcagccagtg gggcgactga ctggttgtac
    15301 tcacgccgct gcctggatgt tgccatctgg cgaactggtc ggcgggcatg aagacgtggg
    15361 tcgccatgtg gcgctggaca aactgttagg ccgccggtca caagaagggg aaagctggca
    15421 gcaaggtgcg gtactggttt ccagtcgtgc cagttatgaa atggtgcaaa agtcggcgat
    15481 gtgcggcgta gagattttgt ttgcggtgtc tgccgcgacc acgcttgctg tagaagtggc
    15541 tgagcgctgt aatctgacac tggtaggttt ttgtaaaccg ggtcgggcaa cggtttatac
    15601 ccatccgcag cgtttgagca attaattaaa ataagtcctg cgatatatat taaattgcag
    15661 gacttattca tttcgtgaat tggtaatgac tccaacttac tgatagtgtt ttatgttcag
    15721 ataatgcccg atgaccttgt catgcagctc caccgatttt gagaacgaca gtgacttccg
    15781 tcccagcctt gccagatgtt gtctcagatt cagattatgt cgctcaatgc gctgagtgta
    15841 acgcttgctg ataacgtgca gctttccctt caggcgtgat tcatacagcg gccagccatc
    15901 cgtcatccat accacgacct caaaggccga cagcaggctc agaagacgct ccagtgtggc
    15961 cagagtgcgt tcaccgaaga cgtgcgccac aaccgtcctc cgtatcctgt catacgcgta
    16021 aaacagccag cgctgacgtg atttagcacc gacgtagccc caatgttcgt ccatttcagc
    16081 gcagacaatc acatcactgc ccggttgtat gtgcgaggtt accgactgcg gcctgagttt
    16141 tttaagtgac gtaaaaccgt gttgaggcca acgcccataa tgcgtgcact ggcgcgacat
    16201 ccgacgccat tcatggccat atcaatgatt ttctggtgcg tatcgggctg agaggcggtg
    16261 taagtgaact gtagttgcca tgttttacgg caatgagagc agagatagcg ctgatgtccg
    16321 gcagtgcttt tgccgttacg caccacgcct tcagtagcgg agcaggaagg acatctgatg
    16381 gaaatggaag ccacgcaagc accttaaaat caccatcata cactaaatca gtaagttggc
    16441 agcattaccg gatattgcgg ccactcatcg gtcagttgat tacgcagggc gtaaatcgcc
    16501 agaatcaggc tggagagata atcaccctgt atgagcggcc agcggtgttg gttgtcgcag
    16561 gccgtggata aatgctgaag gttgtctcgt gttatgcccg ccagcggaat taaaaacgga
    16621 tctttgcgca gcaagttcgc cagcaagata acgagtttct cttctgtctc atcaatgaaa
    16681 tggcccaaac cagggcggct ggccaggcaa caagtgcgtt cataacgctg ttttaactgg
    16741 ggcagacgct ctgctaccca cgtttctggc aaattaagcg ccgaggcgag ttgcgcacgg
    16801 ggagtgaaag tattcagtaa taacagcgcc agcagccgat cgtcgttatc gtgcttttgc
    16861 agcaactgaa aaaagctgcg gcgctcgaag atttccagct gatagcccgc actgccactg
    16921 gcgaaaatgc gggctttgcc gttaagggta aagttgagat agtcaatatc acgcaggatg
    16981 gtcctgcctg aaacgccagt ctgttgcgcc agctcaccag gcgtgcgcgg ctgttgctcc
    17041 agcagatcga caatctttaa ctggcgttcg tttagcatta atccacctga cggaactggc
    17101 taaacgcgtt gactttctcc gcggttaagg tcgtcagaaa accccgtatc aacgtgagca
    17161 gagcatcgta atcggctttt gaaatcatgc cgctgttagc gtgcagatag cgggttggca
    17221 ggcacagcgc aacaaccgga cgcccgccgc ccatcacgtt gtagcgcccg ccatccgtcg
    17281 ctccggtttt catggtggaa aattgcagcg gtaaatcgtt atgtgcggca cagtttttta
    17341 acgctgctac cagtttctgg ttggggaagt agcgcttgtc aaacagcatc agccccggcc
    17401 cctggcccag tttcagcggg tatttaatgt tatcaatgcc cggaacatcg cctgcgacag
    17461 cggtatccag cacgatcact acatccggtt taatgtgttc cgccgaggtt tgtgccccgc
    17521 gtagcccaac ttcttcttcc acgctgccga cgccatacag cgtaatttcg ggattattca
    17581 ccgtctgcaa tagttcagcc atcattgcgc agccgatgcg gttatccagc gccttgccga
    17641 ccactttatc ttcgccccag caggcaaaat tggcttccgg gctaataaaa tcgcccatcg
    17701 ccacaccgcg tttttccacc tcatcgcgac tgtttgcgcc aatatcaatg aacatctcat
    17761 caaatgacag cggctgttgc ctttgctttt ccgttaacgc atgaggcgcg acgaaaccaa
    17821 tcacaccagg gattttcact cccttgtgtg tgcgtatggt tacccgatgg ttgagcatcg
    17881 actgattcca ccagccacca atggtggtga aacgcagaaa accgctctcg tcgatgtggg
    17941 tgaccataaa gccgacttca tccatatgcc cgacaacggc aacttttgga cctttatttc
    18001 ccttacgggc aacaaagctg cccagaccat caaaggtgat ttcattaacg caaggttcca
    18061 gcgtgtttat caggatgtcg cgaacttcct gttcatcgcc gctaacggcg ctggcttcgc
    18121 acaactgttg cagtaactca atgttcatgg acaagctcct gttgcgcggc tttcgctttg
    18181 cggcgtaacc acaatccttt caggacgata atgaatgaaa tgttcagcgc gaggccaatc
    18241 gccagcacca gataaaacga acctaccggc gacatcaggc cgatcagcgg gtcaaagata
    18301 cccaaaccag gtgccagacg tttgattccg aaagcgatca ccagcacgcc ggtaatgccg
    18361 cccgccagcg tattggcggt aatcatcggc aacggagctg ccagagcgta aggtatagcc
    18421 ggttcggttg cgactgtggc accgaccaca atggcactac tggcagcctc tttttcctgt
    18481 cgggtaaaca gtttgggcgc aatgaacgtc gcaagacccg ccgcaacggg cggcatcaac
    18541 gcgacaacgc cgacgatggc gtaccagtca taaatgtgtt tttccagcag tgagaagcag
    18601 aagaaccagg cggttttatt gatggggccg cccatatcga acgccagcat cgcaccgacc
    18661 agaaacgctg ccgcaaactt cattgatgga ggaatggtat tcaggaagtg gagcagcccg
    18721 cccatgaggt cggacatcac cggcccgata acgtagtaag tgagcacgcc gaaaaccagc
    18781 agagtaacga acgggatcag cattgaaccg agcagcggtt gtaatgcttt gccaaggcgc
    18841 actttgcgga accagaagac gaaatagcca atcgccagcc ccagcaccac cgcgccgagg
    18901 aatcccgcac ccgactgggt gccgagcagc gctttgtcgt tcgccagata gcaaaccaga
    18961 aacgccggag cgaaagccgg tttatcggca atcgacgagg caatataagc gcccatgatg
    19021 gggatcataa aggtgaagcc aaggtaaccg atggattcaa ctacccaggt aaacgacggc
    19081 gcgcctttcg acatatcggt atacggcaaa ccgaactgca ccagcatgtt ggcaagcgcc
    19141 accaggatac caccgccgat gacaaacggc agcgccgcag agacgcccgc catcaggtgg
    19201 ctcatcacgc tgccgctttg cacttcctgt ttgccaagct tcacgccgct atctgcggca
    19261 aaaagctgcg agtttgtcgg taattcgctg aaaatctggt cgatattttt caacgccagg
    19321 gagatggcaa tctcataaac tttcttcccg gcaaaccgcg cgcgatcatc accgctcagg
    19381 ccacgcccgg tagcaagaat gacgtaatcg gcagcggcaa tctcttcgct ggataagcgg
    19441 ttttcaacgc cactggaccc ttgagtttcc acttttatgg tatggccgag agaacgggct
    19501 ttctgttcca gggcttccgc caccatgtag gtgtgagcga tcccggcggg gcagttggtg
    19561 atcgcgacaa tacgtaagga tgactccatc gccacttcct tatgagctga gggtttgatt
    19621 taacaaggcc agcacctggt cggtatcgcc ctgttgcagt tgatgaataa attcctggtg
    19681 aataattttg cgacacagtg tgccgatgat tttgacctga tcctcttcgc cgctttgcgg
    19741 cacgccgagg cagatccagc aattgacgtc ttcgccatcg ctggctttcc agtcaatagc
    19801 ctgcgctttg cgggcgaata atacgaacgg ttgtttaacg caggcgcttt taccgtgcgg
    19861 cactgcgaca ccggaaccaa atccagtaga gtgcattttt tcgcgcagca gcagggtttg
    19921 caggaactgg tgtgagtcgg tgataaaacc gttttgtaac gctattgtcg ccaactgctt
    19981 cagaacggaa taagcgccat tgccctgaat attcaggtca atacagcttg cagtaagagc
    20041 tgccattaat cggactccat aaaatatatt ttaatcaatt gtaatggtgg agcgattaag
    20101 tgatgagagg cgatatgtcg gtaaacaatg acaatttgag acagagtgaa aggtcagatt
    20161 tgcggagtaa tgcacataat ggttatttaa ataaaccaca tgaatcatta atgggttatt
    20221 cattattttt gtgatttact cacaatgtat cagggaaata taacttaccg ggagatgtaa
    20281 tatgtttaat ttttcaaatc gaaatttaaa atattgtgcc ggaggcatct ccggcacatt
    20341 gggcaattac ggcaggtaaa acacttcttg cagctcgcta ctcaccgggc tgttatctgg
    20401 gttagcgggc ataacatcgg tcatatattt ccaccaacgt tggcaaacat cagtactggc
    20461 taccgcattc caccgttctt cagattcaat ctctaccatg gcaaacagca gattacgcgc
    20521 tttgtcgagg taaatggcgt agttatgcac accgtgagat ttcaacactg cttccagttc
    20581 cggccagatg ggattatgcc gacgctgata ctcttcgtgg gcgtcggggt ttacctgcat
    20641 gacaaaggct ttgcggatca tgtttgctcc ttacagcgcc agcgcactgg ctagtggtgt
    20701 aacgccgaag cgcttgccga gcgctatcaa ctcttcacgg ctgatggtct gtttcatgcc
    20761 gcccatcgaa taaaccttca ctaatacttg tgctgatttt tctgcggtgt cgattaaacc
    20821 aaaggcttca tccagcgtcg gtccggaacc gaacacaccg tggaagggcc acaacaccag
    20881 cgaatgtttt tgcatctctt gtgcggtcgc ctggccgatt tcgtccgtgc cgggcaccat
    20941 ccacggcaga atgccaacgc catccgggaa tactaccaga cattcggtgc tgccttccca
    21001 cagttggcga gtaaagaccg cggtgtcgtt ttccagtaca taggtgaggg cgatcaggtt
    21061 ggtggcgtgg cagtgcatga tcacccgatc tttaccgttg gtggctttaa tgcgctcgca
    21121 gtgggagaga aagtgagccg gaagttcaga agttggaacg gcttcgttgg ttaaccccca
    21181 gagaatatgg tagcccgcgc catcgctgtc gacttttacg acgcctaagt tagctgcagg
    21241 atcgagctgg acgttacgga agaatttgcc ggagccggtg acaataaacg gcgtatttgc
    21301 cagtaaaggc atgggttggc tgagcggaat atagcgcggt tgtgggtgga agttgtcgtg
    21361 ataaagcgcg atatcggcgt catccaggcg cagcgtcagg ttgccgccgt tgcgctcgtc
    21421 ccagcctttc agctaggcat cggtggtggc tttgatcatt ccctggacaa accaggactg
    21481 ggtaatgttt tgcatgttct gtgttcctgt aaattaggtt gccttgttta gacatggtgc
    21541 ggcttgttcc cctcacccta accctctccc cgtaggggcg aggggactgt ccggagcggt
    21601 gttcagctcc gttgccgcac gaggctatgt ttttctccct cgccctttca gggagagggc
    21661 cggggtgagg gtgacagccc gcatggacat tcgacccgta ggccggataa ggcgctcgtg
    21721 ccgcatccgg cagtgtttac ccacgctggc tcaaaatcgc tttctcataa gcccgcacgc
    21781 tctccagcca ttcgctacct gctggcgtat cgtgatgttg gcaatacatt tcccagaccg
    21841 cctgccgcgg caacgatttc tgctcttcca gcagtgccag acgcgcagtg taatcgcccg
    21901 ccgcttccag cttgcgcagc tcagcggtag gttccagcaa cgcacgcagc agggcttttt
    21961 tcatattgcg tgtaccaatg acccacgcgg caatgcggtt gatagaggca tcgaagaagt
    22021 caaggccgat atgcacccgg tcaaacagat cgtgacgcac aatctcactg gcaattgcct
    22081 gggtttcatc atccagcagc actacgtgat cgctgtccca gcgaaccgga cggctgacgt
    22141 gcagcagcaa ctgcggtaca tacagcatgg cggcggaaat cttgtcggaa atcacttcag
    22201 tcgggtggaa gtgcccggcg tccaggcaca gcgcagtctg gcggctggtg gcatacccca
    22261 tgtaaaactc attggagcca accgtgtagc tctctgcgcc aatgccaaac aatttgctct
    22321 caacggcgtc gatatggtgc gcagggttta gcttctcgct gatcacctca tccagtgctg
    22381 ccagcagacg ctgacgcggg gcgagacggt caacggtgat atctttcata ccatccggga
    22441 tccagatgtt catcaccgat ggtgtgccga gttgctcgcc aaaataggcc gaaacgcgac
    22501 ggctggcttt gcagtgatca atccagaact ggcgaatgct gtcgtcggga tgcgagagcg
    22561 taaagccatc ggcgcttagc ggatgcgaaa agcaggaggg gttaaaatcc agaccgagct
    22621 gattggcttt cgcccattca acccagtttt tgaagtgctc tggtttgatc tggtcgcgcg
    22681 agactggcgt atctgattcc agatagatgg catgtaaatt aagccgtttc ggccccggaa
    22741 tcagccgcat agcctgttcc agatcggcac gtagctcact ggcattacgc gctttgcccg
    22801 gataattgcc tgtggcctga atccccccgg tcagcgaacc ttccgggttt tcaaaaccgg
    22861 aaacatcatc gccctgccag cagtgcattg aaacgggtaa acgatcaagt tggcgcagcg
    22921 cctcctcgac atcaatcccc accgccgcga aacgctgttt cgccagctcc caggcctgtt
    22981 ccagttgagt ggtcatgcgc aaagctcctt tgtctgtcgt gtagagtgaa tctgcgccac
    23041 atagtgggca atttcactgt caggattagg ggtaaaggtg gtcagattcg cggtggtgct
    23101 gacgacctga cggaaatcat ccacattgtt gagttcatcc agcgtcatta actcgatgcc
    23161 gatattgccg agcgttgagg cttcaacagg cccggcgatc acccgaatac cgcaggcatc
    23221 ggcgcatagc tggttgagca gcgtgttctg gcagccgccg ccgacaatat gcagttgcga
    23281 gaaatcttca ccgcgcagct gcgccagctc atgcaacaca tcggcataca gcagcgccag
    23341 actgtcgaaa atacagcgcg ccagttcagc atcacttccc gggatcggtt gcgccgtttc
    23401 ccgacacgca gcctgaattt cgctgcacat ctcgtcagga ttaataaagc gatcgtcatt
    23461 gggattgatg atgaagcggc aggccggaag tgcctgtgtc gcggcgataa gcgccgggag
    23521 atcgttgatt tgccgttcct gaagcactcg ctgaagcagc cataagccca taatattttt
    23581 cagcacccga tagcgacctt ccgccccgcc ttcattggtg atgttggctg ccagcgccgt
    23641 gtcattggta aatggcgtct ggctttcgaa gcccatcaat gaccaggtgc cagaagagag
    23701 ataagcggcg cgtgaaccgt ttaacggcga ggcgataacc gcgctggcgg tatcatggct
    23761 ggcaacggcg accaccggaa tctcattacc ctgcgggcaa atccagtgcc caatgacatt
    23821 acccggatgc gtcgggcgac caaaccaggc tttgttggcc ccgctccacg ccagtagcga
    23881 ctcgtcccag tcgtcgctat tgatattgac cagttgtgtg gtggtggcat tggtatattc
    23941 ccagttcatc ttgccggtca ggcgataact gaagtaatcc ggcatcagca gagcgtgagc
    24001 aatgtgtgga ataagttcag gttgttgctc cgtcagcgca cgcaactgat aaagcgtatt
    24061 gaagggtaga aactggatgc cgctacgctg ataaatatcg cgtttgccga gttgctgttg
    24121 tgcctgcggc atcaggccat tggtgcggct atcgcgataa gcaacgggca ggcccacacg
    24181 ctgaccctgt tggtcgagca gcacaaagtc cacgccccag gtatcaatcc caatgctatc
    24241 gatacgaatc ccttcctcgc acaccttgtt taatccaagg cgaatggcac tttccaggct
    24301 atccacatcc caggtgacat aaccgttttg gctatgcagc ccattgttaa aacgatggat
    24361 ttcgcgcagc gtcaggctgc ggcattcacg ctcgtaacgc gccagcatca cgcgcccact
    24421 ggatgcgccg agatcgacgg cgacacaatt gcgaaaggtc ataatgtgat cctgctgaat
    24481 ttcattacga ccagtctaaa aagcgcctga attcgcgacc ttctcgttac tgacaggaaa
    24541 atgggccatt ggcaaccagg gaaagatgaa cgtgatgatg ttcacaattt gctgaatt
//
